F1000Research最新文献

{"title":"Case Report: <i>Hymenolepis diminuta</i> in an asymptomatic Ecuadorian child.","authors":"Zulbey Rivero de Rodriguez, Ader Ponce, Anthony Vera, Angela Bracho, Anita Murillo","doi":"10.12688/f1000research.155856.2","DOIUrl":"10.12688/f1000research.155856.2","url":null,"abstract":"<p><strong>Background: </strong>The cestode <i>Hymenolepis diminuta</i> is a cosmopolitan parasite, which in the adult stage is usually found in the small intestine of rats and accidentally in humans.</p><p><strong>Case report: </strong>We describe the finding of eggs of this parasite in an asymptomatic 3-year-old child. The child had extremely high IgE values of 1,376 IU/ml. After receiving treatment with Albendazole suspension 400mg/20mL, on the 10th day post-treatment, he showed no <i>H. diminuta</i> eggs in his fecal matter.</p><p><strong>Conclusions: </strong>Detailed morphological review of <i>Hymenolepis nana</i>-like eggs is recommended to distinguish them from <i>H. diminuta</i> eggs.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1119"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Through restful waters and deep commotion: A study on burnout and health impairment of Italian seafarers from the JD-R model perspective.","authors":"Francesco Buscema, Lorenzo Cena, Clarissa Cricenti, Margherita Zito, Lara Bertola, Lara Colombo","doi":"10.12688/f1000research.159198.1","DOIUrl":"10.12688/f1000research.159198.1","url":null,"abstract":"<p><strong>Background: </strong>The work experience of seafarers differs significantly from other land-based occupations due to several factors, particularly remoteness and the restricted work environment. This study seeks to examine the impact of burnout and health impairment in the maritime industry, using the Job Demand-Resources theory as a framework.</p><p><strong>Methods: </strong>To investigate these phenomena, an online questionnaire was sent to 629 Italian seafarers and we conducted analysis on a valid sample of 239 respondents (94.6% men, Mage = 39.44, SD = 12.8). We tested a mediated Structural Equation Model (SEM) aimed at predicting negative health outcomes.</p><p><strong>Results: </strong>The results show that burnout plays a mediating role between job demands (such as workload and cognitive strain) and health impairment (such as sleep quality and physical well-being) (Total Indirect Effect = 0.443, <i>p</i> < .0001) as well as between job resources (such as social support and transformational leadership) and health impairment (Total Indirect Effect = -0.249, <i>p</i> < .0001). Furthermore, the findings highlight the direct influence of occupational resources on seafarers' health.</p><p><strong>Conclusions: </strong>The discussion highlights the urgent need for more research in the field of organisational psychology in the maritime industry and the discrepancies between these findings, which are consistent with the existing maritime literature, and other studies that do not include seafarers in their sample groups.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"19"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11751612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Value of Applying Big Data Analytics in Health Supply Chain Management.","authors":"Dina Al Nuaimi, Niyi Awofeso","doi":"10.12688/f1000research.156525.4","DOIUrl":"10.12688/f1000research.156525.4","url":null,"abstract":"<p><p>This study aims to evaluate the impact of big data analytics (BDA) on the performance of healthcare supply chain management (HCSCMP) by examining both overall efficiency improvements and identifying critical success factors for effective implementation. Through a systematic literature review, the research investigates how BDA enhances real-time decision-making within healthcare supply chains (HCSCs) and identifies the key enablers required for successful BDA adoption. A comprehensive search strategy was employed to analyze 65 papers, resulting in the inclusion of 39 studies published between 2016 and 2023. The review revealed a preference for literature reviews and questionnaires as the primary research methods. The findings indicate that BDA significantly improves HCSCs' efficiency, particularly in real-time decision-making and operational management. However, successful BDA implementation depends on addressing critical enablers and overcoming associated challenges.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1237"},"PeriodicalIF":0.0,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining the effects of anxiety and education level on mental health: The role of spiritual intelligence as an intervening variable in post COVID-19 patients in Indonesia.","authors":"Anis Ansyori, Ahmad Yunus, Sentot Imam, Yuly Peristiowati","doi":"10.12688/f1000research.154599.3","DOIUrl":"10.12688/f1000research.154599.3","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic has profoundly affected global health systems and daily life, exacerbating vulnerabilities, particularly in Indonesia. This study investigates the impact of anxiety and education level on mental health, with spiritual intelligence as an intervening variable among post-COVID-19 patients in Indonesia.</p><p><strong>Methods: </strong>Utilizing a cross-sectional design, data were collected from 390 post-COVID-19 patients in Indonesia. Structured questionnaires assessed anxiety, education level, spiritual intelligence, and mental health. Structural Equation Modeling (SEM) was used to analyze the relationships among these variables.</p><p><strong>Results: </strong>The findings indicate that anxiety significantly affects both spiritual intelligence and mental health, with spiritual intelligence acting as a mediating factor. Additionally, higher educational attainment is positively associated with enhanced spiritual intelligence and improved mental health outcomes.</p><p><strong>Conclusions: </strong>The study underscores the importance of incorporating spiritual development practices into mental health interventions and educational programs to boost resilience and overall well-being in the post-pandemic era. While these findings are promising, the cross-sectional design limits causal inferences, and future research should consider longitudinal studies to examine these relationships over time. These practices can help mitigate the adverse effects of anxiety and educational disparities on mental health.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"916"},"PeriodicalIF":0.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11826076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological, Gross Morphological, And Histopathological Analysis Of Postmortem Cases Of Hanging - An Observational Study.","authors":"Alana Chacko, Chandni Gupta, Vikram Palimar, Deepak Nayak M","doi":"10.12688/f1000research.159606.2","DOIUrl":"10.12688/f1000research.159606.2","url":null,"abstract":"<p><strong>Background: </strong>Death due to hanging is commonly seen. Sometime the ligature mark will be very prominent and in some cases it might not. In those cases, the post-mortem examination with its gross morphological findings and histopathological analysis, becomes significantly important. Objective: The objective of this study was to identify the patterns of epidemiological, gross morphological, and histopathological features in hanging cases.</p><p><strong>Methods: </strong>The study was conducted on 46 cases of hanging and was carried out from February 2023 to June 2024. Their sociodemographic features were collected. Gross morphological analysis of the ligature mark and various measurements were taken. Later tissue from the ligature mark was sent for histopathological analysis. Statistical analysis was performed on the collected parameters.</p><p><strong>Results: </strong>Significant male preponderance was observed in hanging cases. The maximum number of cases of hanging were observed in the fourth decade of life. Daily wage workers were the most significantly affected population. Depression was cited as the cause of suicide in most cases. Carotid intimal tears and injuries to bony and cartilaginous structures were present in smaller numbers. Vital reaction was observed in all 46 cases. Classification of wound vitality showed a correlation to known time since injury.</p><p><strong>Conclusion: </strong>The results of the present study showed that socio-demographic factors play a significant role in the circumstances leading to suicidal deaths. Therefore, in reducing the burden of suicidal deaths, these factors must be addressed. To identify the cause of death as hanging analysis of various gross features and histopathology are very important and should be conducted carefully.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1556"},"PeriodicalIF":0.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cicada minimum age tree: Cryptic speciation and exponentially increasing base substitution rates in recent geologic time.","authors":"Soichi Osozawa, John Wakabayashi","doi":"10.12688/f1000research.76068.4","DOIUrl":"10.12688/f1000research.76068.4","url":null,"abstract":"<p><p>We developed a new time-calibrated phylogenetic tree incorporating primarily endemic Ryukyu Islands cicada data, along with some cryptic species, following the recent global cicada studies by Marshall <i>et al.</i> (2018), Łukasik <i>et al.</i> (2018), Simon <i>et al.</i> (2019), Price <i>et al.</i> (2019), and Hill <i>et al.</i> (2021). A total of 352 specimens were analyzed using BEAST v1.10.4 software with a relaxed clock model. Fossil calibrations dating as far back as the Triassic were adopted, largely following Johnson <i>et al.</i> (2018) and Moulds (2018), with a Quaternary geological event calibration based on Osozawa <i>et al.</i> (2012, 2021b), which was input into BEAST v1.10.4. In the COI tree, the crown age of Cicadoidea was estimated at 200.63 Ma. Tettigarctidae was found to be the oldest lineage, sister to all remaining cicadas. Derotettiginae, at 99.2 Ma, is the next oldest lineage, sister to all other monophyletic cicadas. The Tibicininae clade branched at 66.15 Ma, with the subfamilies Tettigomyiinae, Cicadettinae, and Cicadidae diverging at a crown age of 40.57 Ma. The Cicadinae clade consists of many tribe and genus-specific clades, with numerous cryptic species emerging due to vicariance and adaptive radiation. We estimated the base substitution rate as a function of age, and the results strongly indicate an exponential increase in substitution rates during recent geological time. This increase in cicada biodiversity, including the generation of cryptic species in the Ryukyu Islands and surrounding regions, may have been driven by the spread of C4 grasses and concurrent Quaternary climate changes.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"11 ","pages":"308"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incentives in prescribing, dispensing and pharmaceutical spending: A scientometric mapping.","authors":"Tocaruncho-Ariza L H, Riascos-Ochoa J, Jimenez-Barbosa W G","doi":"10.12688/f1000research.156306.1","DOIUrl":"10.12688/f1000research.156306.1","url":null,"abstract":"<p><strong>Introduction: </strong>Health systems worldwide are struggling to ensure the affordability of medicines. Prescription, dispensing, and pharmaceutical expenditures are key variables that highlight the need to understand how global scientific evidence is generated against factors (implicit and non-explicit) that influence these variables.</p><p><strong>Objectives: </strong>Explore and provide a detailed description of the characteristics of the global scientific production of Open Access articles related to the prescription, dispensing and pharmaceutical expenditure faced by health systems worldwide.</p><p><strong>Methods: </strong>A five-stage scientometric mapping was performed based on a systematic search of 8 databases. The five stages are: i) retrieval, ii) migration, iii) analysis, iv) visualization and v) interpretation.</p><p><strong>Results: </strong>A corpus of evidence from 103 systematic literature reviews was obtained, screened and sifted, visualizing the countries, authors, databases, journals, institutions and time periods that contributed most to evidence generation. Central research themes are identified and phenomena related to article publication are discussed.</p><p><strong>Conclusions: </strong>The analysis reveals a clear leadership of the United Kingdom and the United States in scientific production on prescribing, dispensing and pharmaceutical expenditure in health systems worldwide. This scientific production is mainly focused on financing policies, pharmaceutical incentives and interventions, and rational use of medicines. There is also evidence of the scarcity of scientific production in Latin American publications and authors, which could generate interest for future research.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1333"},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11826077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethiopia's Potato Seed System: Regulatory Challenges, Quality Assurance Issues, and Pathways for Improvement ─ A mini review.","authors":"Lemma Tessema, Ebrahim Seid","doi":"10.12688/f1000research.158093.1","DOIUrl":"10.12688/f1000research.158093.1","url":null,"abstract":"<p><strong>Background: </strong>Ethiopia's potato seed system is currently hindered by a disjointed regulatory framework, insufficient quality assurance processes, and a lack of collaboration among stakeholders, which collectively impede agricultural productivity and food security. The regulatory environment is characterized by inconsistent seed certification practices and a dependence on informal seed sources, negatively affecting the quality of potato seeds available to farmers. Although potatoes play a crucial role in global food security by providing high yields compared to other staple crops, the sector grapples with significant challenges due to bureaucratic inefficiencies, limited technical expertise, and the widespread presence of counterfeit seeds throughout the value chain.</p><p><strong>Methods: </strong>To tackle these challenges, this mini-review outlines potential improvements, stressing the necessity for a unified regulatory framework tailored to the unique issues of vegetatively propagated crops. For this reason, we have used different literature source from web of science, Pubmed, Google Scholar, ResearchGate and other scientific websites. We have documented the most relevant information focusing on potato seed system, regulatory frameworks, quality assurance bottlenecks and pathways for improvement across the seed value chain.</p><p><strong>Results: </strong>our paper highlights key recommendations that includes enhancing training for regulatory staff, investing in research for disease-resistant varieties, and bolstering public-private partnerships to encourage innovation and resource sharing. Furthermore, improving traceability in the seed supply chain is essential for maintaining seed quality and integrity.</p><p><strong>Conclusions: </strong>This review calls for a comprehensive strategy that fosters stakeholder engagement and promotes sustainable practices to rejuvenate Ethiopia's potato seed system, thereby supporting the livelihoods of millions of smallholder farmers and strengthening national food security through integrated seed sector development and capacity improvement of the seed regulatory body as well as smallholder farmers.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1348"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11782929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Advances in Biopesticide Research and Development with a Focus on Microbials.","authors":"Kahsay Tadesse Mawcha, Lawrence Malinga, Debbie Muir, Jing Ge, Dennis Ndolo","doi":"10.12688/f1000research.154392.2","DOIUrl":"10.12688/f1000research.154392.2","url":null,"abstract":"<p><p>Biopesticides are pest control products derived from natural sources such as microbes, macro-organisms (insects and pathogens), plant extracts, and certain minerals. Many biopesticides are considered environmentally safe and can complement or substitute conventional chemical pesticides. They can also be highly specific or broad spectrum with a unique mode of action controlling a wide range of pest species. Due to their target-specificity and low to no environmental residuality, biopesticides conform to the 3 pillars of Climate-Smart Agriculture, the Sustainable Development Goals, and, ultimately, the Paris Agreement. This review focuses largely on microbial biopesticides derived from fungi, bacteria, viruses, and nematodes. It discusses (i) the various microbial biopesticide formulations, (ii) the mode of microbial biopesticide action, (iii) the factors that affect the potential efficacy of biopesticides, (iv) challenges to the adoption of microbial biopesticides, and (v) the role of microbial biopesticides in Integrated Pest Management programs. Finally, advancements in application techniques, as well as future research directions and gaps, are highlighted.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1071"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Unmasking the Uncommon\": A case series of multi-drug resistant Elizabethkingia meningoseptica causing late-onset sepsis and meningitis in preterm neonates.","authors":"Prajnha U P, Anisha Maria Fernandes, Suchitra Shenoy M, Sinchana Bhat","doi":"10.12688/f1000research.158137.2","DOIUrl":"10.12688/f1000research.158137.2","url":null,"abstract":"<p><p><i>Elizabethkingia meningoseptica</i> is an uncommon nosocomial pathogen that causes meningitis, pneumonia, and sepsis in neonates and in immunocompromised individuals. It exhibits resistance to many commonly employed first-line antibiotics used to treat gram-negative pathogens. Herein, we present three cases of late-onset sepsis with multi-drug resistant (MDR) <i>Elizabethkingia meningoseptica</i> in high-risk neonates. Case 1 was a one-day-old preterm low-birth-weight infant who presented with respiratory distress syndrome and septic shock. The patient was intubated and administered empirical broad-spectrum antibiotics and antifungal agents. Blood culture grew <i>Candida krusei,</i> hence Amphotericin B was initiated. Repeat blood culture on day 27 showed gram-negative bacilli, identified as <i>Elizabethkingia meningoseptica</i> by MALDI-TOF <i>.</i> Antibiotic susceptibility testing (AST) revealed resistance to Piperacillin/Tazobactam, but sensitivity to Vancomycin, Levofloxacin, and Minocycline. IV Vancomycin was administered, which resulted in clinical improvement and negative blood culture results. Case 2 was an eleven-day-old preterm, low-birth-weight baby who presented with fever. Initial investigations revealed normal complete blood counts (CBC) parameters and elevated CRP levels. Blood and CSF cultures isolated <i>Elizabethkingia meningoseptica</i> with a similar AST pattern. Intravenous Ciprofloxacin was initiated with clinical improvement and negative follow-up blood cultures. Case 3 was a one-day-old preterm baby, appropriate-to-gestational age, presenting with respiratory distress syndrome. The infant was intubated and started on inotropic support and intravenous antibiotics. Blood cultures on day 4 showed <i>Elizabethkingia meningoseptica</i> and Vancomycin was started. Follow-up cultures on days 6 and 14 grew <i>Acinetobacter baumannii.</i> A combination of Levofloxacin and Colistin was added, and blood cultures were negative after seven days, with clinical improvement. <i>Elizabethkingia meningoseptica</i> is a significant cause of hospital-acquired infections, especially in Neonatal Intensive Care Unit (NICU), leading to outbreaks. Clinicians must have a high degree of suspicion of <i>E. meningoseptica</i> for gram-negative bacilli causing sepsis and meningitis in high-risk patients. Recent technological advances have enabled accurate speciation to guide therapy and reduce morbidity and mortality rates.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1367"},"PeriodicalIF":0.0,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11814954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143406481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}