F1000Research最新文献

{"title":"Cybersecurity Awareness as a Mediating Variable in the Relationship between ICS and AIS in Iraqi State Banks.","authors":"Younis Ahmed Al-Mohammedi, Ahmed S Tarkh, Hamzah N Al-Jumaili, Nedhal Aziz Mahdi","doi":"10.12688/f1000research.175421.2","DOIUrl":"10.12688/f1000research.175421.2","url":null,"abstract":"<p><strong>Research objective: </strong>This research aims to study the relationship between internal control and accounting information security, while exploring the role of cybersecurity awareness as a mediating variable that can contribute to strengthening this relationship.</p><p><strong>Research significance: </strong>This research gains its significance from bridging the knowledge gap in accounting literature concerning the integration of internal control systems with information security in the face of cyber challenges.</p><p><strong>Research methodology and tools: </strong>Considering the nature of the problem and the research objectives, this study follows the steps of the descriptive-analytical method. The aim is to determine the role of cybersecurity awareness as a mediating variable in strengthening the relationship between internal control systems and accounting information security. This includes analyzing data and information related to enhancing the importance of cybersecurity awareness in the local environment, both theoretically and empirically. The analysis was conducted through a survey examining the relationship between internal control systems and accounting information security, mediated by cybersecurity awareness among employees at different administrative levels in the banks included in the study sample. The PLS Smart software was used to process and analyze data. The research found that internal control systems are closely linked to the security of accounting information, with the mediating factor being cybersecurity awareness. This finding indicates a positive and significant relationship. This demonstrates the crucial and positive role of control in protecting data when cybersecurity awareness is raised.</p><p><strong>Recommendations: </strong>The researchers recommend that banks adopt best practices for information security protection and implement strong and clear policies and procedures for cybersecurity awareness.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"294"},"PeriodicalIF":0.0,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13084233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147722300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mentor's Perspective on Structured Clinical Mentoring in the Arab Context.","authors":"Jacqueline Maria Dias, Semiyu Adejare Aderibigbe, Mini Sara Abraham, Abdullah A A Sankar, Mohammed M M Mansour, Mohammed Gamil Awadh, Yousseif Mohamed Yousseif Mohamed Awadalla Elsatary, Mohammed B A Ballour, Muhammad Arsyad Subu, Nabeel Al Yateem, Fatma Refaat Ahmed, Al-Hasan Mohammed Abdullah Al-Azzani, Edric Paul Dias, Richard Mottershead","doi":"10.12688/f1000research.177515.2","DOIUrl":"https://doi.org/10.12688/f1000research.177515.2","url":null,"abstract":"<p><strong>Background: </strong>Mentorship is essential in nursing education to foster clinical skills, critical thinking, and professional identity. Despite extensive research on mentorship, few studies have addressed its role in the Arab cultural context. This study explored nursing mentors' clinical learning experiences through mentorship within the cultural context of the United Arab Emirates (UAE).</p><p><strong>Methods: </strong>A qualitative approach was employed, involving 20 mentors supervising fourth-year nursing students during their final clinical placement at a semi-public university in the UAE. The placement occurred from January to May 2024, as part of the Consolidation of Practice course, comprising 240 hours of clinical training. Structured and semi-structured in-depth interviews were conducted with the participants, and the data were transcribed verbatim. To analyse the data, an inductive thematic approach was adopted, and some data were quantified for additional insights.</p><p><strong>Results: </strong>Four main themes emerged regarding the benefits of structured mentoring within the cultural context: critical for practical training, confidence building, bridging theory and practice and mutual learning. The essential mentoring skills identified were effective communication, patience, and understanding. Structured mentoring frequency positively influenced students' clinical learning. The strengths of the structured mentorship included exposure to real-life scenarios, improved communication, and the development of practical skills. Opportunities for improvement included increasing mentor-student interactions, enhancing the programme's structured nature, and integrating technological tools. The mentors recommended reassessing mentorship duration, increasing hands-on clinical exposure, strengthening mentor collaboration, and promoting student accountability.</p><p><strong>Conclusion: </strong>Effective mentorship in nursing education in the UAE requires integrating theory and practice, clear communication, and leveraging technology to overcome barriers. Strengthening structured mentor-student interactions through focused workshops and refined programme structures can bridge educational gaps. Such enhancements can enable nursing students to develop into competent and confident healthcare professionals, who are familiar with culturally informed mentorship practices.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"432"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13146465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147835709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structure of the (Total) Transformation Monoids Under Rank N Generators.","authors":"Hala M Sulaiman, Asawer Al-Aadhami","doi":"10.12688/f1000research.173831.2","DOIUrl":"10.12688/f1000research.173831.2","url":null,"abstract":"<p><p>Throughout this paper our study focuses on transformation semigroups. These kinds of semigroups are the corner stone of semigroup theory. This is because every semigroup is isomorphic to transformation semigroup. The (total) transformation monoid <math><msub><mi>T</mi> <msub><mi>X</mi> <mi>n</mi></msub> </msub> </math> on a finite set <math><msub><mi>X</mi> <mi>n</mi></msub> <mo>=</mo> <mrow><mo>{</mo> <mn>1</mn> <mo>,</mo> <mn>2</mn> <mo>,</mo> <mo>…</mo> <mo>,</mo> <mi>n</mi> <mo>}</mo></mrow> </math> where <math><mspace></mspace> <mi>n</mi> <mspace></mspace> <mo>≥</mo> <mspace></mspace> <mn>0</mn></math> , <math><mi>n</mi> <mspace></mspace> <mo>∈</mo> <mspace></mspace> <mi>Z</mi></math> , is a semigroup of mapping that takes a set <math><msub><mi>X</mi> <mi>n</mi></msub> </math> into itself, under the operation of composition of mapping with identity <math><msub><mi>I</mi> <msub><mi>X</mi> <mi>n</mi></msub> </msub> </math> . In this paper, we use an algebraic method for considering the monoid <math><msub><mi>T</mi> <mrow> <msub><mrow><mo>(</mo> <mi>Fl</mi> <mo>)</mo></mrow> <mi>n</mi></msub> <mrow><mo>(</mo> <mi>G</mi> <mo>)</mo></mrow> </mrow> </msub> </math> , where an independence algebra <math> <msub><mrow><mo>(</mo> <mi>Fl</mi> <mo>)</mo></mrow> <mi>n</mi></msub> <mrow><mo>(</mo> <mi>G</mi> <mo>)</mo></mrow> </math> is a disjointed union of sets of the form <math><mi>G</mi> <msub><mi>x</mi> <mi>i</mi></msub> <mspace></mspace></math> for all 1 <math><mspace></mspace> <mo>≤</mo> <mspace></mspace> <mi>i</mi> <mspace></mspace> <mo>≤</mo> <mspace></mspace> <mi>n</mi> <mo>.</mo></math> Firstly, particular attention is paid to find the isomorphism between <math><msub><mi>T</mi> <mrow> <msub><mrow><mo>(</mo> <mi>Fl</mi> <mo>)</mo></mrow> <mi>n</mi></msub> <mrow><mo>(</mo> <mi>G</mi> <mo>)</mo></mrow> </mrow> </msub> </math> and the endomorphism monoid <math><mi>End</mi> <msub><mrow><mo>(</mo> <mi>F</mi> <mi>ℓ</mi> <mo>)</mo></mrow> <mi>n</mi></msub> <mrow><mo>(</mo> <mi>G</mi> <mo>)</mo></mrow> <mo>.</mo></math> Secondly, the embeddedness of <math><msub><mi>T</mi> <mrow> <msub><mrow><mo>(</mo> <mi>Fl</mi> <mo>)</mo></mrow> <mi>n</mi></msub> <mrow><mo>(</mo> <mi>G</mi> <mo>)</mo></mrow> </mrow> </msub> </math> in (full) wreath product of <math><msub><mi>T</mi> <mi>n</mi></msub> </math> by <math><msup><mi>G</mi> <mi>n</mi></msup> </math> has been found. Finally, the description of Green's relation of <math><msub><mi>T</mi> <mrow> <msub><mrow><mo>(</mo> <mi>Fl</mi> <mo>)</mo></mrow> <mi>n</mi></msub> <mrow><mo>(</mo> <mi>G</mi> <mo>)</mo></mrow> </mrow> </msub> </math> has been provided.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"170"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13084235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147722280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Port Performance through Digital Transformation: The Role of Networking Capability and Organizational transformation in Indonesian Container Ports.","authors":"Buyung Pramitra, Mochammad Al Musadieq, Tri Wulida Afrianty, Teuku Noerman","doi":"10.12688/f1000research.176261.3","DOIUrl":"10.12688/f1000research.176261.3","url":null,"abstract":"<p><p>Although digital transformation in port management has been widely discussed, previous studies have not extensively examined how organizational capabilities translate into performance through digital adoption at ports. This study addresses this gap by positing digital adoption as a mediating mechanism linking network capabilities and organizational transformational characteristics to port performance at container ports in Indonesia. This study aims to examine the influence of networking capabilities and organizational transformational characteristics on digital adoption, as well as its impact on port performance at container ports in Indonesia. This study also analyzes the mediating role of digital adoption in the relationship between organizational capabilities and port performance. The study uses an explanatory design with a quantitative approach through a survey method. Data were collected using structured questionnaires from 103 container ports throughout Indonesia with respondents being decision makers and core port function managers, namely General Managers or Operations Managers or Marketing Manag-ers if the General Manager was not available. Data analysis was conducted using Structural Equation Modeling with a Partial Least Squares approach through SmartPLS. The results of the study indicate that networking and organizational transformational capabilities have a significant effect on digital adoption, and digital adoption has a significant effect on port performance. This study also found that digital adoption significantly mediates the relationship between organizational transformation and port performance. However, this study does not prove that digital adoption mediates the influence of net-working capability on port performance.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"87"},"PeriodicalIF":0.0,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13033128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147581206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the effects of fluids and antibiotics in an acute murine model of sepsis: study protocol for the National Preclinical Sepsis Platform-01 (NPSP-01) Study.","authors":"Forough Jahandideh, Asher A Mendelson, Patricia C Liaw, Sean E Gill, Stephane Bourque, Alison E Fox-Robichaud, Gediminas Cepinskas, Kimberly F Macala, Janet Sunohara-Neilson, Doreen Engelberts, David Sontag, Dhruva J Dwivedi, Ian-Ling Yu, Onon Batnyam, Kashimbi Mbuta, Dean A Fergusson, Monica Taljaard, Braedon McDonald, Manoj M Lalu","doi":"10.12688/f1000research.163800.3","DOIUrl":"10.12688/f1000research.163800.3","url":null,"abstract":"<p><strong>Background: </strong>Sepsis remains a leading cause of mortality in critical care. Despite extensive preclinical research on sepsis pathophysiology, the development of effective therapies has been largely unsuccessful. Key obstacles include limited construct validity of animal models, insufficient methodological rigor and the lack of collaborative frameworks akin to clinical trials. These issues plague not only sepsis research, but preclinical research in general. The National Preclinical Sepsis Platform (NPSP), an interdisciplinary network under Sepsis Canada, addresses these challenges in sepsis research through multilaboratory, randomized, controlled preclinical studies. NPSP-01 will establish baseline conditions for future investigations using an acute fecal-induced peritonitis model of sepsis.</p><p><strong>Methods: </strong>This randomized, controlled study will evaluate the effect of standard sepsis therapy in a mouse model of sepsis across six centres. Interlaboratory variability and the interaction of biological sex on outcomes will also be examined. C57BL/6 mice of both sexes will be randomized into sham (healthy control) + treatment, sepsis, or sepsis + treatment groups. Sepsis will be induced via intraperitoneal injection of fecal slurry, while sham mice will receive vehicle control. Antibiotics and fluids will be administered to treatment groups at 4 hours post-induction, and mice with be humanely killed at 8 hours post-induction. The primary outcome is plasma interleukin-6 levels. Secondary outcomes include biological (blood gas and chemistry, white blood cell count, bacterial load), clinical (body weight, core temperature, sepsis score, mortality as measured by surrogate humane endpoints), and feasibility measures.</p><p><strong>Conclusions: </strong>NPSP-01 will be the first multilaboratory study of sepsis and represents a shift in preclinical critical illness research, mirroring the rigor of clinical multicenter trials. By addressing procedural standardization, interlaboratory variability, and sex-based differences, this study aims to enhance the reliability and translational relevance of preclinical findings. The outcomes of NPSP-01 will establish foundational data for future investigations and provide a roadmap for rigorous collaborative preclinical studies to accelerate the evaluation of novel sepsis therapies.</p><p><strong>Registration: </strong>PreclinicalTrials.eu PCTE0000552Protocol Version 1.0, October 21, 2024.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"472"},"PeriodicalIF":0.0,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13049416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147622242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine Learning Assisted Hybrid Cuckoo Search for Predictive Optimization in Renewable Energy Systems.","authors":"Noor Dalaf, Iraq T Abbas","doi":"10.12688/f1000research.172760.2","DOIUrl":"https://doi.org/10.12688/f1000research.172760.2","url":null,"abstract":"<p><strong>Background: </strong>Due to the intermittent, nonlinear, and uncertain behavior of renewable energy sources (res) such as solar and wind, grid stability and reliability require very high forecasting and optimization skills as widely reported in the literature. Traditional optimization methods work very well in small or static systems but are suffer difficulty on large-scale, dynamic and stochastic renewable environment due to their NP-hard nature.</p><p><strong>Methods: </strong>The framework introduces the concept of a Machine Learning-Assisted Hybrid Cuckoo Search (ML-HCS) that combines CS with a hybrid metaheuristic and integrates Long Short-Term Memory (LSTM) networks for forecasting based on both regression models of LSTMs and hybrid optimization algorithms. LSTM model produces predictive signals that help inform the search trajectory of CS, enabling better exploration-exploitation tradeoff of resource scheduling on uncertainty.</p><p><strong>Results: </strong>Simulation experiments on benchmark renewable energy datasets showed that ML-HCS not only converges 12% faster than the best of the GA, PSO, and classical CS, but also achieves 7-10% better quality of solutions and 9% higher robustness. This model also adapted better in multi-objective optimization tasks: cost minimization, scheduling stability and prediction accuracy.</p><p><strong>Conclusions: </strong>Finally, the ML-HCS framework provides a prediction-oriented, data-driven, scalable optimization methodology for renewable energy systems. Its use of machine learning and metaheuristic search provide for high forecasting accuracy and resiliency in operation, which will enable its future large scale smart grid and renewable energy management applications.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"436"},"PeriodicalIF":0.0,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13110386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147766938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of Pathogenic <i>PKHD1</i> Variants in Infants with Autosomal Recessive Polycystic Kidney Disease from the Dhofar Region, Oman.","authors":"Intisar Al Alawi, Maha Al Awadi, Fatma Al Awaid, Joshua Pillai, Matthew Sampson, Juliana E Arcila Galvis, Ashwaq Al Maimani, Zainab Al Hashmi, John A Sayer","doi":"10.12688/f1000research.171123.2","DOIUrl":"10.12688/f1000research.171123.2","url":null,"abstract":"<p><strong>Background: </strong>Autosomal recessive polycystic kidney disease (ARPKD) is a rare, inherited disorder primarily affecting the kidneys and liver. Disease-causing variants in <i>PKHD1</i> lead to a disruption of the encoded protein fibrocystin/polyductin. This study aims to identify disease causing variants in <i>PKHD1</i> in families from the Dhofar region of Oman.</p><p><strong>Methods: </strong>We conducted a case series of six families with antenatal diagnoses of ARPKD and postnatal deaths. Genetic testing was performed on neonates using Sanger sequencing and next-generation sequencing (NGS) to detect variants in <i>PKHD1.</i> <i>In silico</i> analysis of mutational consequences was performed.</p><p><strong>Results: </strong>5 distinct homozygous variants in the <i>PKHD1</i> gene were identified, including three pathogenic frameshift variants (c.6111_6112delTT, c.7011dupT and c.9550dupT), a nonsense variant (c.340C>T) and a homozygous deletion spanning exons 58-60 of the <i>PKHD1.</i> These alleles have not been reported in previous studies. <i>In silico</i> modelling identified pathogenic alleles, predicted to lead to either truncated protein products or nonsense-mediated decay.</p><p><strong>Discussion: </strong>Our findings identify disease causing <i>PKHD1</i> variants in this genetically distinct Dhofar population, potentially due to factors such as geographical isolation, consanguinity, and founder effects. The identification of previously undescribed variants underscores the need for regional genetic studies in understanding ARPKD and its genotype-phenotype correlations.</p><p><strong>Conclusion: </strong>This study reveals distinct <i>PKHD1</i> disease-causing variants in the Dhofar region of Oman, contributing to the broader genetic understanding of ARPKD. These findings highlight the value of region-specific genetic research in identifying new disease causing variants.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"1212"},"PeriodicalIF":0.0,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12856244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146104493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antioxidant Support for the Corneal Endothelium: Evidence from Vitamin C Supplementation in Hard Cataract Phacoemulsification.","authors":"Syska Widyawati, Ratna Sitompul, Septelia I Wanandi, Melva Louisa, Aria Kekalih, Rina Ldr Nora","doi":"10.12688/f1000research.170846.3","DOIUrl":"https://doi.org/10.12688/f1000research.170846.3","url":null,"abstract":"<p><strong>Background: </strong>Phacoemulsification is one of the most frequent surgeries in the world. However, prolonged use of phacoemulsification machines produces reactive oxygen species which will damage corneal endothelial cells. Ascorbic acid has an antioxidant capacity to neutralize oxidative stress in the anterior chamber. This study will investigate the protective effect of ascorbic acid on corneal endothelial cells in patients with hard nuclear cataracts.</p><p><strong>Methods: </strong>This study is a double-blinded randomized controlled trial. Samples will be divided into three groups, and 500 mg vitamin C three times daily (1500 mg/day), or placebo will be received for seven weeks. Clinical characteristics, ascorbic acid, malondialdehyde, and total antioxidant capacity of patients in serum and aqueous humor will be measured before and after intervention and phacoemulsification.</p><p><strong>Conclusions: </strong>Data from this study will reveal the protective effect of oral vitamin C supplementation on the corneal endothelial cells in patients with hard nucleus cataracts.This trial has been registered at ClinicalTrials.gov (identifier: NCT06781970; registered on 17 January 2025). The trial record is available at: https://clinicaltrials.gov/ct2/show/NCT06781970.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"1117"},"PeriodicalIF":0.0,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13146457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147835682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of the Complete Mitochondrial Genome and Evaluation of COI Barcoding in <i>Philonis inermis</i> (Coleoptera: Curculionidae: Cryptorhynchinae) Using Genome Skimming.","authors":"Alejandra Clavijo-Giraldo, Sandra Uribe Soto, Andrés Gómez-Palacio","doi":"10.12688/f1000research.170584.3","DOIUrl":"10.12688/f1000research.170584.3","url":null,"abstract":"<p><strong>Background: </strong><i>Philonis inermis</i> is a Neotropical stem-galling weevil specialized on the invasive vine <i>Passiflora foetida</i> and represents a promising candidate for biological control. However, no genomic or barcoding data have previously been available for this genus, limiting its taxonomic resolution and risk assessment potential.</p><p><strong>Methods: </strong>We used shallow whole-genome sequencing of two individuals reared under controlled conditions to assemble, annotate, and compare the complete mitochondrial genome of <i>P. inermis</i> with other Cryptorhynchinae. BUSCO analysis was performed to recover nuclear single-copy orthologs and additional multicopy markers. <i>Cytochrome c</i> oxidase subunit I (COI) sequences from 20 Colombian specimens were analyzed together with 24 Cryptorhynchinae barcodes from GenBank to evaluate intra- and interspecific divergence.</p><p><strong>Results: </strong>The <i>P. inermis</i> mitogenome is 15,120 bp in length, AT-rich (77.0%), and contains 36 genes, including 13 protein-coding genes, 21 tRNAs, and two rRNAs. The tRNA-Ile was not detected, likely obscured within the variable control region, as reported for other cryptorhynchine weevils. Phylogenetic analysis based on mitogenomic sequences placed <i>P. inermis</i> as a well-supported clade closely related to <i>Eucryptorrhynchus.</i> COI barcode analysis revealed extremely low intraspecific divergence (pairwise K2P ≤ 0.006) and a pronounced barcode gap distinguishing <i>P. inermis</i> from other Cryptorhynchinae species. Genome-skimming assemblies yielded 196 single-copy orthologs, 28 duplicated BUSCOs, and a rich set of multicopy nuclear markers, including extensive rRNA fragments (18S, 28S, 5.8S, 16S) and core histones (H2A, H2B, H3, H4), which are provided as extended data for future phylogenomic applications.</p><p><strong>Conclusion: </strong>This study presents the first complete mitochondrial genome for the genus <i>Philonis</i> and demonstrates the utility of COI barcoding for the current molecular identification of <i>P. inermis</i>, in a context where comparative mitogenomic data remain scarce. These genomic resources provide a foundation for future integrative taxonomic, comparative, and evolutionary studies, and support further evaluation of <i>P. inermis</i> as a potential biological control agent against <i>P. foetida.</i></p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"1174"},"PeriodicalIF":0.0,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategic Management of Low Carbon Travel in Longevity Tourism Evidence from Thailand.","authors":"Warach Madhyamapurush","doi":"10.12688/f1000research.178615.2","DOIUrl":"https://doi.org/10.12688/f1000research.178615.2","url":null,"abstract":"<p><p>The increase in longevity tourism, driven by an aging populace and wellness travel, raises environmental issues, notably carbon emissions from travel. Thailand is becoming a key destination for this type of tourism, necessitating strategic frameworks to integrate low-carbon travel methods into its management. This research intends to evaluate the carbon footprint of longevity tourism travel patterns in Thailand and provide strategic management solutions to encourage low-carbon travel and improve long-term health and well-being results. A mixed-method approach was used to gather primary data via structured questionnaires and travel activity logs from 450 longevity tourists in selected Thai destinations, along with secondary data on emission factors from national energy and tourism databases. Carbon footprint assessment was conducted using an LCA-based carbon footprint analysis. Descriptive statistics and One-Way ANOVA in IBM SPSS (version 28) analyzed emissions variations across transportation modes, accommodation types, dietary choices, and activity patterns. Thematic analysis on qualitative responses highlighted common behavioral patterns and perceptions related to low-carbon travel practices. According to the LCA-based carbon footprint analysis, transportation (347 kg CO2e per capita) and lodging (160 kg CO2e) had the highest emissions, compared to lifestyle choices (42.5 kg CO2e) and strategic awareness factors (50 kg CO2e). Significant emission disparities among different travel modes, housing types, food patterns, and awareness levels were confirmed by one-way ANOVA results (p < 0.01). Longevity tourism in Thailand is made more sustainable by intentional low-carbon planning and optimized infrastructure, while extended stays and energy-efficient lodgings lower emissions.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"404"},"PeriodicalIF":0.0,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13139847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147835781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}