F1000Research最新文献

{"title":"Prevalence of musculoskeletal symptoms from online learning during the COVID-19 epidemic: a systematic review and meta-analysis.","authors":"Tanawat Gotum, Orawan Keeratisiroj, Wutthichai Jariya","doi":"10.12688/f1000research.152382.2","DOIUrl":"10.12688/f1000research.152382.2","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this research was to assess the prevalence of musculoskeletal symptoms in online students.</p><p><strong>Materials and methods: </strong>A systematic review and meta-analysis were performed by searching the PubMed, Cochrane Library, SCOPUS, Web of Science, ScienceDirect, ProQuest, CINAHL plus with full text, and Wiley InterScience databases. A total of 3,749 studies were identified between January 2020 and December 2023. The Joanna Briggs Tool for studies reporting prevalence was used to assess the quality of studies. Jamovi 2.4 was used in the meta-analysis.</p><p><strong>Results: </strong>Sixteen studies were included and used for the meta-analysis. The average age of participants was 22 years, with an age range of 17-45 years, Sample range 120-3,705. There were 6 studies of high quality, 9 studies of medium quality and 1 study of low quality. The areas with the highest prevalence of musculoskeletal pain were the neck (51%, 95% CI = 36-66%, I ² = 99.96), lower back (51%, 95% CI = 42-59%, I ² = 99.96) and shoulder (36%, 95% CI = 26-47%, I ² = 99.61).</p><p><strong>Conclusions: </strong>The shift to online learning during the COVID-19 pandemic has emerged as a potential factor influencing musculoskeletal pain in students. Educational institutions should study the duration of online learning that begins to impact student injury outcomes.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"790"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12150206/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A causality investigation into stock prices and macroeconomic indicators in the Indian stock market.","authors":"Sanjay Singh Chauhan, Pradeep Suri, Firoz Alam, Umme Hani, Amar Johri, Farman Ali","doi":"10.12688/f1000research.157041.3","DOIUrl":"https://doi.org/10.12688/f1000research.157041.3","url":null,"abstract":"<p><strong>Background of the study: </strong>The systematic impact of macroeconomic variables on stock market returns makes it crucial to comprehend the link between macroeconomic variables and the stock market. Stock prices are closely linked to macroeconomic indicators, a crucial aspect for investors, policymakers, and researchers in emerging markets like India, influencing investment decisions and policy formulation.</p><p><strong>Methods: </strong>The autoregressive distributed lag (ARDL) model was used in this study to examine the causal links between specific macroeconomic factors and Indian stock prices from April 2009 to March 2023.</p><p><strong>Results: </strong>The outcomes of the research suggest that macroeconomic variables exert influence on the Indian stock market, across the short and long term. Moreover, the results of the paired Granger causality test suggest that the domestic macroeconomic variables possess predictive significance for stock prices in the Indian stock market.</p><p><strong>Conclusion: </strong>The study reveals that macroeconomic variables significantly impact the Indian stock market, highlighting the need for investors and portfolio managers to monitor these conditions to optimize returns and mitigate risks. The Reserve Bank of India should maintain an optimal money supply to prevent inflation and exchange rate fluctuations, while bolstering the export sector and facilitating imports through initiatives like Atma-nirbhar Bharat Abhiyan and Make in India. Policies focusing on productivity, infrastructure, and a favourable business environment are also crucial. Therefore, it is crucial for investors and portfolio managers to consistently analyse the current macroeconomic conditions in order to maximize their profits and minimize risks. This research has extensive significance for comprehending the intricate connections between the stock market and macroeconomic issues.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1299"},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Evaluation of the Thai Version of the Burdened Caregiver Scale for Schizophrenia and Co-occurring Methamphetamine Use: A Pilot Study.","authors":"Ek-Uma Imkome","doi":"10.12688/f1000research.52288.3","DOIUrl":"10.12688/f1000research.52288.3","url":null,"abstract":"<p><strong>Objective: </strong>To develop and test the psychometric properties of the Thai version of the Impact and Burden of Care Scale for Caregivers of Persons with Schizophrenia and Co-occurring Methamphetamine Use (TIBSCSM).</p><p><strong>Methods: </strong>This pilot study involved 142 caregivers of individuals with schizophrenia and methamphetamine use. Sample adequacy was assessed using the Kaiser-Meyer-Olkin (KMO) method, while Bartlett's test evaluated the item correlation matrix. Exploratory factor analysis (EFA) was conducted to identify underlying factors.</p><p><strong>Results: </strong>The 32-item TIBSCSM showed convergent validity correlations with two quality-of-life measures. The KMO value was 0.90, and Bartlett's Test of Sphericity yielded χ ² = 5248.5, df = 496, p < 0.001. The Content Validity Index (CVI) was 1, indicating high internal consistency reliability (α = 0.90). EFA identified four constructs: physical function, self-esteem, role and social enjoyment, and relationship satisfaction. The model exhibited strong reliability and validity, with an average variance extracted (AVE) of 0.948 and composite reliability (CR) of 0.987, accounting for 64.90% of the variance.</p><p><strong>Conclusion: </strong>The TIBSCSM scale provides valuable insights for psychiatric nurses and mental health teams to measure the impact and burden experienced by caregivers of individuals with schizophrenia and methamphetamine use. It is particularly useful for nursing, research, education, and clinical practice, especially in addressing the caregiver burdens exacerbated during the COVID-19 pandemic.</p><p><strong>Implication for nursing and research: </strong>The TIBSCSM, developed in the Thai context, can facilitate studies evaluating variations in caregiver impact across different settings.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"10 ","pages":"484"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12120408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Influencing Organisational Politics and their Relationship with Emotional Intelligence and Employee Behavior: A PLS-SEM Modelling.","authors":"Sonakshi Bhatia, Babita Rawat, Dhani Shanker Chaubey, Farman Ali","doi":"10.12688/f1000research.151721.2","DOIUrl":"10.12688/f1000research.151721.2","url":null,"abstract":"<p><strong>Background: </strong>This study explores the complex relationship between organizational politics, emotional intelligence and employee behavior in contemporary settings. Organizational politics, which is widespread in organizational settings, has a substantial impact on different aspects of employee behavior. Emotional Intelligence has become a vital factor in individuals' capacity to successfully traverse the complexities of an organization. This study consolidates current material to offer insights into the impact of organizational politics on employee behavior and the mediating role of emotional intelligence in this connection.</p><p><strong>Methods: </strong>A survey was undertaken with a sample size of 500 employees hailing from several Information Technology (IT) and Information Technology Enabled Services (ITES) firms in the Dehradun (Uttarakhand) region. The study employed quantitative methodologies to investigate the correlations between Emotional Intelligence, Perceived Organizational Politics and Employee Behavior. The data were evaluated using Partial Least Squares Structural Equation Modelling (PLS-SEM) to examine the hypothesized correlations and mediation effects.</p><p><strong>Results: </strong>The study identified substantial correlations between Emotional Intelligence, Perceived Organizational Politics, and Employee Behavior. Emotional Intelligence was discovered to have a positive impact on Behavioral Dynamics. Perceived Organizational Politics had a substantial influence on both Emotional Intelligence and Behavioral Dynamics. Factors such as Need for Power, Relationship Conflict, Resource Constraints, Role Conflict, and Workforce Diversity were discovered to have an impact on Perceived Organizational Politics.</p><p><strong>Conclusions: </strong>The results confirm strong connections between organizational politics, emotional intelligence, and employee behavior, highlighting the significance of these concepts in comprehending employee behavior in organizational environments. The study proposes that enhancing employees' emotional intelligence can alleviate the adverse effects of organizational politics, resulting in enhanced behavioral dynamics. The study also addresses the limits, outlines potential areas for further research, and highlights the managerial implications. It suggests that firms should prioritize the development of emotional intelligence to cultivate a favorable work environment.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"996"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12123262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: A giant ruptured splenic hydatic cyst in a patient with a complete situs inversus: Diagnostic challenge and intra-operative difficulties.","authors":"Amina Chaka, Wael Boujelbène, Amin Chaabouni, Mohamed Ali Bahloul, Nizar Kardoun, Salah Boujelben","doi":"10.12688/f1000research.159480.2","DOIUrl":"10.12688/f1000research.159480.2","url":null,"abstract":"<p><p>The splenic localization of hydatid cysts is extremely rare. A 50-year-old obese female who consults with a painful and febrile syndrome of the right hypochondrium. Abdominal ultrasound and a CT scan computed tomography revealed a complete situs inversus, a mass of the right hypochondrium measuring 152 mm with membrane detachment, and infiltration of the surrounding fat, evoking a type II complicated splenic hydatic cyst. The patient was operated on in an emergency via midline laparotomy. Exploration revealed situs inversus, an angiant cyst of the spleen. Exposition of the splenic pedicle is difficult. The samples were then infected. Total splenectomy was performed. The postoperative period was unproblematic, and the patient was discharged with antibiotic and antiparasitic treatment and habitual vaccination.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1480"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11934099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mediating role of Social Support and Self-efficacy on Academic stress and Student's Psychological well-being among University Students in Mogadishu -Somalia.","authors":"Ali Dahir Mohamed, Abdulkadir Jeilani","doi":"10.12688/f1000research.155275.2","DOIUrl":"10.12688/f1000research.155275.2","url":null,"abstract":"<p><strong>Background: </strong>Academic stress is a significant factor affecting students' psychological well-being, particularly in higher education. Understanding the mediating roles of social support and self-efficacy can provide insights into how these factors influence students' psychological well-being in public and private universities.</p><p><strong>Methods: </strong>The study examined the mediating roles of social support and self-efficacy in the relationship between academic stress and psychological well-being among university students in Mogadishu, Somalia. Utilizing a stratified sampling technique, data were collected from 663 students across public (52.6%) and private (47.4%) universities through a structured questionnaire and analyzed using path analysis to assess direct and indirect effects. Structural equation modeling technique was used for data analysis.</p><p><strong>Results: </strong>The analysis revealed a significant direct effect of academic stress on psychological well-being (β = 0.087, p = 0.001). Social support was significantly related to Academic stress (β = 0.117, p = 0.031) and self-efficacy (β =0.088, p = 0.021). However, both social support (β = 0.099, p = 0.000) and self-efficacy (β = 0.646, p = 0.000) were significantly related to psychological well-being. The mediating analysis showed that social support partially mediated the relationship between academic stress and psychological well-being (Indirect effect = 0.012, CI [0.002, 0.024], p = 0.000), while self-efficacy did not mediate this relationship (Indirect effect = 0.057, CI [0.006, 0.111], p = 0.068).</p><p><strong>Conclusions: </strong>The findings suggest a significant positive impact of academic stress on psychological well-being, while social support partially mediates this relationship, highlighting its buffering role. Conversely, self-efficacy, although positively contributing to psychological well-being, does not mediate the effect of academic stress. These results underscore the importance of robust social support systems and targeted interventions to enhance students' coping mechanisms and overall psychological well-being. Study limitations and implication are discussed.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1108"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12141996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid optimization technique for matrix chain multiplication using Strassen's algorithm.","authors":"Srinivasarao Thota, Thulasi Bikku, Rakshitha T","doi":"10.12688/f1000research.162848.1","DOIUrl":"10.12688/f1000research.162848.1","url":null,"abstract":"<p><strong>Background: </strong>Matrix Chain Multiplication (MCM) is a fundamental problem in computational mathematics and computer science, often encountered in scientific computing, graphics, and machine learning. Traditional MCM optimization techniques use Dynamic Programming (DP) with Memoization to determine the optimal parenthesization for minimizing the number of scalar multiplications. However, standard matrix multiplication still operates in O(n ³) time complexity, leading to inefficiencies for large matrices.</p><p><strong>Methods: </strong>In this paper, we propose a hybrid optimization technique that integrates Strassen's algorithm into MCM to further accelerate matrix multiplication. Our approach consists of two key phases: (i) matrix chain order optimization, using a top-down memoized DP approach, we compute the best multiplication sequence, and (ii) hybrid multiplication strategy, we selectively apply Strassen's algorithm for large matrices (n ≥ 128), reducing the complexity from O(n ³) to O(n ^2.81), while using standard multiplication for smaller matrices to avoid recursive overhead. We evaluate the performance of our hybrid method through computational experiments comparing execution time, memory usage, and numerical accuracy against traditional MCM and Strassen's standalone multiplication.</p><p><strong>Results: </strong>Our results demonstrate that the proposed hybrid method achieves significant speedup (4x-8x improvement) and reduces memory consumption, making it well-suited for large-scale applications. This research opens pathways for further optimizations in parallel computing and GPU-accelerated matrix operations.</p><p><strong>Conclusion: </strong>This study presents a hybrid approach to Matrix Chain Multiplication by integrating Strassen's algorithm, reducing execution time and memory usage. By selectively applying Strassen's method for large matrices, the proposed technique improves efficiency while preserving accuracy. Future work can focus on parallel computing and GPU acceleration for further optimization.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"341"},"PeriodicalIF":0.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12000801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>In vitro</i> antitumor capacity of extracts obtained from the plants <i>Plukenetia volubilis</i> (Sacha inchi) and <i>Moringa oleifera</i> in gastric cancer.","authors":"Jose Vargas, Natalia Arbelaez, Denny Cardenas, Javier Murillo, Victoria Ospina, Sara Robledo, Javier Soto","doi":"10.12688/f1000research.158563.2","DOIUrl":"10.12688/f1000research.158563.2","url":null,"abstract":"<p><strong>Background: </strong>Gastric cancer is the fifth most common cancer and the third leading cause of cancer deaths worldwide. Perioperative or adjuvant chemotherapy improves survival in patients with stage 1B or higher cancers. <i>Moringa oleifera</i> and <i>Plukenetia volubilis</i> (Sacha inchi) have been reported to enhance various biological functions, including antitumor and antiproliferative activity.</p><p><strong>Methods: </strong>In order to evaluate this potential present in crude extracts of the leaves of these plants, as well as the seed oil of <i>P.volubilis</i>, the antitumor activity was determined according to the effect of these derivatives on different biological parameters such as cytotoxicity, proliferation, cell cycle, apoptosis (among others), in AGS cells (CRL-1739).</p><p><strong>Results: </strong>All extracts tested were cytotoxic at 90 and 160 μg/ml concentrations <i>. P. volubilis</i> seed oil showed 95% mortality at 1% concentration (CC ₅₀ = 46.7%). Cell proliferation was inhibited, and all extracts affected the cell cycle, but the <i>P. volubilis</i> oil significantly induced an accumulation of AGS cells in the sub G1 phase, inducing DNA fragmentation as a mechanism of cell death. The ethanolic <i>M. oleifera</i> leaf extract also inhibited cell migration.</p><p><strong>Conclusion: </strong><i>M. oleifera</i>, <i>P. volubilis</i> leaf extracts and <i>P. volubilis</i> seed oil can potentially be antitumor products. Further validation in a murine model of gastric cancer is needed to investigate the antitumor potential of these extracts further and to continue the development of herbal products that can help in the management of this type of tumor.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"194"},"PeriodicalIF":0.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12120421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular docking studies and molecular dynamic simulation analysis: To identify novel ATP-competitive inhibition of Glycogen synthase kinase-3β for Alzheimer's disease.","authors":"Suggala Ramya Shri, Yogendra Nayak, Sreedhara Ranganath Pai","doi":"10.12688/f1000research.145391.2","DOIUrl":"10.12688/f1000research.145391.2","url":null,"abstract":"<p><strong>Background: </strong>The discovery of an ideal and effective therapy is urgently required for the treatment of Alzheimer's disease (AD). The main pathological hallmarks of Alzheimer's disease that appear before the clinical symptoms are neurofibrillary tangles, amyloid plaques, brain inflammation, and neuronal atrophy throughout the cerebral cortex and hippocampus. GSK-3β (Glycogen Synthase Kinase-3β) is regarded as the most important and promising target for therapeutic use because GSK-3β expression levels increase with age and are the most abundant and hyperactive in the brains of patients with AD. GSK-3β activation or upregulation can contribute to neurodegeneration by promoting amyloid beta (Aβ) production and tau hyperphosphorylation. Whereas the underlying mechanism for abnormal production of GSK-3β in AD brains remains unclear.</p><p><strong>Methods: </strong>Maestro was used, which is Schrodinger, for our computational simulation studies. In the present work, different modules that were used in previous studies with a little modification, the modules such as Protein Preparation with the help of Protein Preparation Wizard, Ligand Preparation with the help of LigPrep, for ADME (Absorption, Distribution, Metabolism and Excretion) prediction Qikprop was used, for docking studies Glide module was used, Binding energy prediction the Prime was used and Molecular dynamic simulation (MDs) studies done using Desmond.</p><p><strong>Results: </strong>Our focus is mainly on an <i>in-silico</i> approach, focusing on library generation; first draw an IMID2 (imidazo [1,5-a]pyridine-3-carboxamide) scaffold structure at Enamine and subjected it to a substructure search to target the receptor grid region (ATP-competitive site) of 6Y9R. They were then subjected to various screening processes. Finally, nine compounds were subjected to MDs studies.</p><p><strong>Conclusions: </strong>Nine compounds showed good results with the most stable interactions. Among all the MD studies, the compound (Z3336252116) has shown good interaction and a good docking score. Further experiments and studies are required to confirm these results.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"773"},"PeriodicalIF":0.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12121352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reference genome and reproduction-focused transcriptome for the threatened alpine tree frog ( <i>Litoria verreauxii alpina</i>).","authors":"Alexander S Wendt, Laura Brannelly","doi":"10.12688/f1000research.163701.1","DOIUrl":"10.12688/f1000research.163701.1","url":null,"abstract":"<p><p>The alpine tree frog ( <i>Litoria verreauxii alpina</i>) is a threatened species found only above 1,200 meters within the Australian Alps. This species' distribution has been severely limited due to the pathogentic amphibian chytrid fungus, and current populations persist by recruitment. Here, we provide the first publicly available genome for the genus. We used PacBio HiFi reads as well as Omni-C scaffolding data to construct a high-quality genome. We also generated a reproduction focused transcriptome from brain, liver, and gonad tissues. The genome was 2.77 Gb in length and consisted of 962 contigs with a contig N50 of 37.2 Mb and an L50 of 19. This study provides the first publicly available reference genome for the <i>Litoria</i> genus to assist in conservation and reproduction focused works in amphibian management.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"514"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}