F1000ResearchPub Date : 2025-03-26eCollection Date: 2024-01-01DOI: 10.12688/f1000research.157487.1
Helga Elke Lister, Karien Mostert, Tanita Botha, Emma Field, Danté Knock, Natasha Mubi, Stefani Odendaal, Megan Rohde, Filip Maric
{"title":"Development and validation of a Knowledge, Attitudes and Practices (KAP) questionnaire for healthcare professionals on environmental sustainability in healthcare in Southern Africa.","authors":"Helga Elke Lister, Karien Mostert, Tanita Botha, Emma Field, Danté Knock, Natasha Mubi, Stefani Odendaal, Megan Rohde, Filip Maric","doi":"10.12688/f1000research.157487.1","DOIUrl":"10.12688/f1000research.157487.1","url":null,"abstract":"<p><strong>Background: </strong>The triple planetary crisis of climate change, environmental pollution, and biodiversity loss is increasingly driving poor health outcomes worldwide. Healthcare systems and services are often not environmentally sustainable and compound the problem, while healthcare professionals are also recognised as key leaders in advancing sustainable healthcare. To adopt this leadership position, healthcare professionals' knowledge, attitudes, and practices regarding environmental sustainability in healthcare must be established. This article reports the development and validation of a new instrument for this purpose that corresponds to the specificities of the Southern African context.</p><p><strong>Methods: </strong>Questionnaire development followed a seven-stage process. Information was obtained from a 2021 study titled 'South African Healthcare Professionals' Knowledge, Attitudes, and Practices Regarding Environmental Sustainability in Healthcare: A Mixed-Methods Study' to develop the instrument. Information was also sourced from the literature regarding environmental sustainability and healthcare to generate the first questionnaire with 29 items. The following stages included two rounds of expert input, separated by a pilot study with the target population to receive feedback regarding the instrument's structure, relevance, and length. Content validity was determined through statistical analysis.</p><p><strong>Results: </strong>Feedback was received from nine experts in stage two and 13 pilot-study participants in stage four and incorporated to improve the questionnaire. In stage six, the questionnaire was rated by seven experts. The content validity index of the questionnaire was calculated at two different stages, after which the indices were compared. Following a final edit, the questionnaire has 24 questionnaire items. The closing analysis calculated the scale content validity index average (S-CVI/Ave) of 0,922; this indicates that the final questionnaire has excellent content validity.</p><p><strong>Conclusion: </strong>A questionnaire that assesses the knowledge, attitudes and practices of healthcare professionals regarding environmental sustainability in Southern Africa has been developed and validated. This questionnaire can now be used for further studies in Southern Africa.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1308"},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11885900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F1000ResearchPub Date : 2025-03-25eCollection Date: 2024-01-01DOI: 10.12688/f1000research.152800.2
Thalia Angela, Siti Wahyuni, Susanna Halim
{"title":"The effect of soaking heat-polymerized acrylic resin denture base in avocado seed extract ( <i>Persea americana</i> Mill.) on the inhibition of denture-plaque microorganisms biofilm growth.","authors":"Thalia Angela, Siti Wahyuni, Susanna Halim","doi":"10.12688/f1000research.152800.2","DOIUrl":"10.12688/f1000research.152800.2","url":null,"abstract":"<p><strong>Background: </strong>Heat polymerized acrylic (HPA) resins are known to have high porosity that contributes to increased surface roughness and microcrack formation in stress areas. This facilitates the attachment and growth of polymicrobial biofilms contributing to increased antimicrobial resistance. This research aims to study avocado seeds effect on denture-plaque microorganism mono-species and polymicrobial biofilm on HPA resin.</p><p><strong>Methods: </strong>This study uses 144 samples (n=144), namely HPA resin discs covered with mono-species and polymicrobial biofilms. The discs are soaked for 8 hours in the 5%, 10%, 15%, 20% avocado seed extract, positive control (alkaline peroxide), and negative control (aquadest). Each disc is shaken with a vortex mixer for 1 minute, and 100 μL is added into 96-well microplates with three times repetition and incubated for 24 hours. A microtiter plate biofilm formation assay is then conducted. The inhibition values are determined from the percentage inhibition value formula which requires absorption values from a microplate reader (595 nm). The research data are analyzed using a univariant test, and a one-way ANOVA test, accompanied by Welch ANOVA on non-homogenous data.</p><p><strong>Results: </strong>In this research, it is found that the MBIC <sub>50</sub> of avocado seed extract against the mono-species of <i>C. albicans</i> (5%), <i>C. glabrata</i> (5%), <i>A. odontolyticus</i> (15%), <i>S. gordonii</i> (15%), <i>S. aureus</i> (10%), while against polymicrobial was 20%. There is a significant effect of soaking HPA resin in avocado seed extract on the inhibition of mono-species and polymicrobial biofilms with a value of p<0.001 (p<0.05).</p><p><strong>Conclusion: </strong>The MBIC <sub>50</sub> of avocado seed extract in polymicrobial biofilm group is higher than that in the mono-species biofilm groups. Hence, 20% avocado seed extract is concluded as the effective concentration to inhibit denture-plaque microorganism biofilm.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"933"},"PeriodicalIF":0.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11806257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F1000ResearchPub Date : 2025-03-21eCollection Date: 2024-01-01DOI: 10.12688/f1000research.149817.2
Elena Jesús Alvarado Cáceres, Enaidy Reynosa Navarro, Lindon Vela Meléndez
{"title":"Economic factors influencing the empowerment of Peruvian women.","authors":"Elena Jesús Alvarado Cáceres, Enaidy Reynosa Navarro, Lindon Vela Meléndez","doi":"10.12688/f1000research.149817.2","DOIUrl":"10.12688/f1000research.149817.2","url":null,"abstract":"<p><strong>Objective: </strong>To determine whether economic factors are crucial in empowering women, guiding them towards growth and development opportunities, achieving empowerment, and contributing to two sustainable development goals of the 2030 development agenda: ending poverty and achieving gender equality.</p><p><strong>Methodology: </strong>The research was foundational, with a phenomenological and hermeneutic design. The applied technique was in-depth interviews with 12 women who had started a business within the last five years in a region of Peru.</p><p><strong>Results: </strong>It is evident that economic factors are decisive in business experiences and decisions, highlighting the necessity of having contingency funds to prevent operational impacts. Through entrepreneurship, women achieved economic independence, enabling them to support their families and impacting their empowerment. It concludes that to promote economic opportunity equality, addressing financing needs, encouraging economic independence, strengthening family empowerment, improving customer management, and facilitating access to government funds are essential.</p><p><strong>Conclusions: </strong>The narrative of the participants provides a solid foundation for designing specific policies and support programs that boost the economic empowerment of women entrepreneurs and encourage their active participation in the business sphere.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1182"},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11971627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing socioeconomic status through dental and associated tissue characteristics: A cross-sectional study for human identification.","authors":"Ceena Denny, Srikant Natarajan, Jasmine Jophy, Nandita Kp, Amita Juanita Lewis, Shwetha Yellapurkar","doi":"10.12688/f1000research.161533.2","DOIUrl":"10.12688/f1000research.161533.2","url":null,"abstract":"<p><strong>Background: </strong>Dental identification methods are employed to determine a person's identity in forensic odontology. Additionally, analyzing a person's teeth can provide insights into their socioeconomic status, which may assist in the process of identification. Our study aimed to assess the correlation between dental health status and SES among individuals, with a focus on identifying predictors of SES based on dental health indicators.</p><p><strong>Methods: </strong>A cross-sectional study was conducted to evaluate the correlation between dental health status and socioeconomic status among 135 individuals. who had visited the Department of Oral Medicine for various forms of dental care. SES was measured according to a modified Kuppuswamy scale. The associations between SES and dental health indicators were analyzed using chi-square tests for categorical variables and t-tests for continuous variables.</p><p><strong>Results: </strong>Dental caries is more common in lower SES groups, attributed to factors like poor nutrition and hygiene. Partial and complete edentulism are also more prevalent in lower SES populations, often due to financial constraints and lack of awareness, leading to extractions rather than restorations. However, urban populations, regardless of SES, show greater utilization of dental restorations, likely due to the concentration of dentists in cities and access to community-based dental camps offering low-cost treatments. Periodontal diseases further reflect SES disparities. Studies show that individuals from lower SES backgrounds report more severe periodontal issues, such as gingival swelling, while higher SES groups report milder symptoms like gingival bleeding, indicating earlier intervention.</p><p><strong>Conclusion: </strong>SES plays a vital role in shaping health and lifestyle outcomes. The findings in our study demonstrate the value of incorporating SES indicators, such as education, occupation, marital status, and residence, into forensic investigations to enhance the precision of identification processes.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"220"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F1000ResearchPub Date : 2025-03-17eCollection Date: 2024-01-01DOI: 10.12688/f1000research.152349.2
Luisa Cassera, Alessia Calabrò, Aschieri Filippo
{"title":"Positive events in psychotherapy: What do adolescents and young adults say is helpful?","authors":"Luisa Cassera, Alessia Calabrò, Aschieri Filippo","doi":"10.12688/f1000research.152349.2","DOIUrl":"10.12688/f1000research.152349.2","url":null,"abstract":"<p><strong>Background: </strong>The significant challenge in adolescent and young adult therapy lies in the fact that research in this field does not provide many clinical indications. This study addresses domains contributing to the establishment and sustenance of engagement, satisfaction, and progress among adolescents and young adults in their treatment by delving into the impact of events that, from the perspective of clients, have positively influenced their therapeutic process.</p><p><strong>Methods: </strong>Employing a qualitative research approach, we conducted semi-structured interviews with 13 adolescents and young adults undergoing therapy, recounting positive and constructive events during their treatment.</p><p><strong>Results: </strong>A structured thematic analysis revealed six primary domains of positive events: events linked to the management of the setting, events shaping the definition of therapy goals, occurrences tied to the therapist's active role, collaborative events between therapists and clients, and events associated with both clients' external and internal worlds.</p><p><strong>Conclusions: </strong>The findings suggest that working with adolescents shares similarities with psychotherapy involving adult clients but demands specific attention to adolescents and young adults' families, surrounding environment, and rapidly changing needs.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1025"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F1000ResearchPub Date : 2025-03-17eCollection Date: 2025-01-01DOI: 10.12688/f1000research.160010.2
Sebastián Cardona-Acevedo, Erica Agudelo-Ceballos, Diana Arango-Botero, Alejandro Valencia-Arias, Juana De La Cruz Ramírez Dávila, Jesus Alberto Jimenez Garcia, Carlos Flores Goycochea, Ezequiel Martínez Rojas
{"title":"Applications of Machine Learning (ML) in the context of marketing: a bibliometric approach.","authors":"Sebastián Cardona-Acevedo, Erica Agudelo-Ceballos, Diana Arango-Botero, Alejandro Valencia-Arias, Juana De La Cruz Ramírez Dávila, Jesus Alberto Jimenez Garcia, Carlos Flores Goycochea, Ezequiel Martínez Rojas","doi":"10.12688/f1000research.160010.2","DOIUrl":"10.12688/f1000research.160010.2","url":null,"abstract":"<p><p>Currently, machine learning applications in marketing allow to optimize strategies, personalize experiences and improve decision making. However, there are still several research gaps, so the objective is to examine the research trends in the use of machine learning in marketing. A bibliometric analysis is proposed to assess the current scientific activity, following the parameters established by PRISMA-2020. Machine learning applications in marketing have experienced steady growth and increased attention in the academic community. Key references, such as Miklosik and Evans, and prominent journals, such as IEEE Access and Journal of Business Research, have been identified. A thematic evolution towards big data and digital marketing is observed, and thematic clusters such as \"digital marketing\", \"interpretation\", \"prediction\", and \"healthcare\" stand out. These findings demonstrate the continued importance and research potential of this evolving field.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"92"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F1000ResearchPub Date : 2025-03-17eCollection Date: 2024-01-01DOI: 10.12688/f1000research.154967.2
Michael D Garber, Tarik Benmarhnia, Audrey de Nazelle, Mark Nieuwenhuijsen, David Rojas-Rueda
{"title":"The epidemiologic case for urban health: conceptualizing and measuring the magnitude of challenges and potential benefits.","authors":"Michael D Garber, Tarik Benmarhnia, Audrey de Nazelle, Mark Nieuwenhuijsen, David Rojas-Rueda","doi":"10.12688/f1000research.154967.2","DOIUrl":"10.12688/f1000research.154967.2","url":null,"abstract":"<p><p>We discuss how epidemiology has been and can continue to be used to advance understanding of the links between urban areas and health informed by an existing urban-health conceptual framework. This framework considers urban areas as contexts for health, determinants of health and modifiers of health pathways, and part of a complex system that affects health. We highlight opportunities for descriptive epidemiology to inform the context of urban health, for example, by characterizing the social and physical environments that give rise to health and the actions that change those conditions. We then describe inferential tools for evaluating the impact of group-level actions (e.g., interventions, policies) on urban health, providing some examples, and describing assumptions and challenges. Finally, we discuss opportunities and challenges of applying systems thinking and methods to advance urban health. While different conceptual frames lead to different insights, each perspective demonstrates that urban health is a major and growing challenge. The effectiveness of urban health knowledge, action, and policy as the world continues to urbanize can be informed by applying and expanding upon research and surveillance methods described here.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"950"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F1000ResearchPub Date : 2025-03-11eCollection Date: 2025-01-01DOI: 10.12688/f1000research.157763.2
Truong Tuan Linh, Nguyen Thi Thanh Huyen
{"title":"An extension of Trust and TAM model with TPB in the adoption of digital payment: An empirical study in Vietnam.","authors":"Truong Tuan Linh, Nguyen Thi Thanh Huyen","doi":"10.12688/f1000research.157763.2","DOIUrl":"10.12688/f1000research.157763.2","url":null,"abstract":"<p><strong>Background: </strong>Digital payment systems are pivotal in the digital economy, relying on the interplay between internet technology and e-vendors. While the Technology Acceptance Model (TAM) and the Theory of Planned Behavior (TPB) have been extensively used to explain technology adoption, the role of trust in financial technology adoption remains underexplored. This study addresses this gap by developing an extended Trust-TAM-TPB model, providing a comprehensive framework to analyze digital payment adoption in emerging markets.</p><p><strong>Methods: </strong>A quantitative approach was adopted, analyzing survey data from 509 respondents using Structural Equation Modeling (SEM). The extended model examines both technological factors (perceived usefulness, perceived ease of use) and trust-related factors (trust's influence on behavioral intention via subjective norms, attitude, and perceived behavioral control).</p><p><strong>Results: </strong>Findings confirm that trust is a significant determinant of digital payment adoption, influencing both perceived usefulness and subjective norms. However, a negative relationship was found between perceived usefulness (PU) and attitude (ATT), suggesting that while users recognize the benefits of digital payments, their attitudes may still be shaped by traditional cash-based habits and security concerns. These insights challenge traditional TAM assumptions and emphasize the importance of trust in driving adoption.</p><p><strong>Conclusions: </strong>This study contributes to technology acceptance literature by integrating trust into the TAM-TPB framework and highlighting its dual role in shaping both perceived usefulness and behavioral intention. Practically, the findings suggest that policymakers and financial institutions should prioritize trust-building strategies, including fraud prevention measures, financial literacy programs, and transparent transaction policies, to accelerate digital payment adoption in developing economies. These insights are particularly relevant for Vietnam's Northern mountainous regions, where digital payment penetration remains low.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"127"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11969139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Negative perceptions toward older adults and life satisfaction among community-dwelling older citizens in Japan.","authors":"Yuho Shimizu, Kenichiro Sato, Susumu Ogawa, Daisuke Cho, Yoshifumi Takahashi, Daichi Yamashiro, Yan Li, Tomoya Takahashi, Keigo Hinakura, Ai Iizuka, Tomoki Furuya, Hiroyuki Suzuki","doi":"10.12688/f1000research.149132.2","DOIUrl":"10.12688/f1000research.149132.2","url":null,"abstract":"<p><strong>Background: </strong>With the rapid aging of the population, increasing life satisfaction among older adults is essential. Negative perceptions of older adults are internalized, leading to poor mental health. This study hypothesized that participants with more negative perceptions of older adults would have lower life satisfaction.</p><p><strong>Methods: </strong>A cross-sectional survey of older adults was conducted across five wards and four cities in Tokyo, Japan. Participants responded to questions regarding demographics, life satisfaction, and negative perceptions of older adults. Data from 285 participants (264 women, <i>M</i> = 71.97 years) were analyzed.</p><p><strong>Results: </strong>The intraclass correlation coefficient for life satisfaction concerning residential areas was. 03 (95% confidence interval [CI] = [-.03, .10]). Instead of multilevel models, a multiple regression model with life satisfaction as the dependent variable and negative perceptions of older adults and demographics as the independent variables yielded the best fit. Results indicated that participants with more negative perceptions of older adults reported lower life satisfaction ( <i>β</i> = -.16, 95% CI = [-.28, -.04], <i>p</i> = .008), supporting our hypothesis.</p><p><strong>Conclusions: </strong>This study was constrained by limited variance in residential areas and a predominantly female participant pool. Previous studies have shown that higher life satisfaction is associated with increased social participation and extended life expectancy, and interventions aimed at enhancing life satisfaction in older adults are significant. Further exploration is warranted to ascertain whether a causal relationship exists, wherein more negative perceptions of older adults diminish life satisfaction.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"467"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F1000ResearchPub Date : 2025-03-11eCollection Date: 2024-01-01DOI: 10.12688/f1000research.154392.2
Kahsay Tadesse Mawcha, Lawrence Malinga, Debbie Muir, Jing Ge, Dennis Ndolo
{"title":"Recent Advances in Biopesticide Research and Development with a Focus on Microbials.","authors":"Kahsay Tadesse Mawcha, Lawrence Malinga, Debbie Muir, Jing Ge, Dennis Ndolo","doi":"10.12688/f1000research.154392.2","DOIUrl":"10.12688/f1000research.154392.2","url":null,"abstract":"<p><p>Biopesticides are pest control products derived from natural sources such as microbes, macro-organisms (insects and pathogens), plant extracts, and certain minerals. Many biopesticides are considered environmentally safe and can complement or substitute conventional chemical pesticides. They can also be highly specific or broad spectrum with a unique mode of action controlling a wide range of pest species. Due to their target-specificity and low to no environmental residuality, biopesticides conform to the 3 pillars of Climate-Smart Agriculture, the Sustainable Development Goals, and, ultimately, the Paris Agreement. This review focuses largely on microbial biopesticides derived from fungi, bacteria, viruses, and nematodes. It discusses (i) the various microbial biopesticide formulations, (ii) the mode of microbial biopesticide action, (iii) the factors that affect the potential efficacy of biopesticides, (iv) challenges to the adoption of microbial biopesticides, and (v) the role of microbial biopesticides in Integrated Pest Management programs. Finally, advancements in application techniques, as well as future research directions and gaps, are highlighted.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1071"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}