F1000Research最新文献

{"title":"The epidemiologic case for urban health: conceptualizing and measuring the magnitude of challenges and potential benefits.","authors":"Michael D Garber, Tarik Benmarhnia, Audrey de Nazelle, Mark Nieuwenhuijsen, David Rojas-Rueda","doi":"10.12688/f1000research.154967.2","DOIUrl":"10.12688/f1000research.154967.2","url":null,"abstract":"<p><p>We discuss how epidemiology has been and can continue to be used to advance understanding of the links between urban areas and health informed by an existing urban-health conceptual framework. This framework considers urban areas as contexts for health, determinants of health and modifiers of health pathways, and part of a complex system that affects health. We highlight opportunities for descriptive epidemiology to inform the context of urban health, for example, by characterizing the social and physical environments that give rise to health and the actions that change those conditions. We then describe inferential tools for evaluating the impact of group-level actions (e.g., interventions, policies) on urban health, providing some examples, and describing assumptions and challenges. Finally, we discuss opportunities and challenges of applying systems thinking and methods to advance urban health. While different conceptual frames lead to different insights, each perspective demonstrates that urban health is a major and growing challenge. The effectiveness of urban health knowledge, action, and policy as the world continues to urbanize can be informed by applying and expanding upon research and surveillance methods described here.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"950"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Negative perceptions toward older adults and life satisfaction among community-dwelling older citizens in Japan.","authors":"Yuho Shimizu, Kenichiro Sato, Susumu Ogawa, Daisuke Cho, Yoshifumi Takahashi, Daichi Yamashiro, Yan Li, Tomoya Takahashi, Keigo Hinakura, Ai Iizuka, Tomoki Furuya, Hiroyuki Suzuki","doi":"10.12688/f1000research.149132.2","DOIUrl":"10.12688/f1000research.149132.2","url":null,"abstract":"<p><strong>Background: </strong>With the rapid aging of the population, increasing life satisfaction among older adults is essential. Negative perceptions of older adults are internalized, leading to poor mental health. This study hypothesized that participants with more negative perceptions of older adults would have lower life satisfaction.</p><p><strong>Methods: </strong>A cross-sectional survey of older adults was conducted across five wards and four cities in Tokyo, Japan. Participants responded to questions regarding demographics, life satisfaction, and negative perceptions of older adults. Data from 285 participants (264 women, <i>M</i> = 71.97 years) were analyzed.</p><p><strong>Results: </strong>The intraclass correlation coefficient for life satisfaction concerning residential areas was. 03 (95% confidence interval [CI] = [-.03, .10]). Instead of multilevel models, a multiple regression model with life satisfaction as the dependent variable and negative perceptions of older adults and demographics as the independent variables yielded the best fit. Results indicated that participants with more negative perceptions of older adults reported lower life satisfaction ( <i>β</i> = -.16, 95% CI = [-.28, -.04], <i>p</i> = .008), supporting our hypothesis.</p><p><strong>Conclusions: </strong>This study was constrained by limited variance in residential areas and a predominantly female participant pool. Previous studies have shown that higher life satisfaction is associated with increased social participation and extended life expectancy, and interventions aimed at enhancing life satisfaction in older adults are significant. Further exploration is warranted to ascertain whether a causal relationship exists, wherein more negative perceptions of older adults diminish life satisfaction.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"467"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Advances in Biopesticide Research and Development with a Focus on Microbials.","authors":"Kahsay Tadesse Mawcha, Lawrence Malinga, Debbie Muir, Jing Ge, Dennis Ndolo","doi":"10.12688/f1000research.154392.2","DOIUrl":"10.12688/f1000research.154392.2","url":null,"abstract":"<p><p>Biopesticides are pest control products derived from natural sources such as microbes, macro-organisms (insects and pathogens), plant extracts, and certain minerals. Many biopesticides are considered environmentally safe and can complement or substitute conventional chemical pesticides. They can also be highly specific or broad spectrum with a unique mode of action controlling a wide range of pest species. Due to their target-specificity and low to no environmental residuality, biopesticides conform to the 3 pillars of Climate-Smart Agriculture, the Sustainable Development Goals, and, ultimately, the Paris Agreement. This review focuses largely on microbial biopesticides derived from fungi, bacteria, viruses, and nematodes. It discusses (i) the various microbial biopesticide formulations, (ii) the mode of microbial biopesticide action, (iii) the factors that affect the potential efficacy of biopesticides, (iv) challenges to the adoption of microbial biopesticides, and (v) the role of microbial biopesticides in Integrated Pest Management programs. Finally, advancements in application techniques, as well as future research directions and gaps, are highlighted.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1071"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unsteady MHD flow of tangent hyperbolic ternary hybrid nanofluid in a darcy-forchheimer porous medium over a permeable stretching sheet with variable thermal conductivity.","authors":"Asfaw Tsegaye Moltot, Eshetu Haile Gorfie, Gurju Awgichew Zergaw, Hunegnaw Dessie","doi":"10.12688/f1000research.158629.2","DOIUrl":"10.12688/f1000research.158629.2","url":null,"abstract":"<p><strong>Background: </strong>This research investigates the unsteady magnetohydrodynamic (MHD) flow, heat, and mass transfer of tangent hyperbolic ternary hybrid nanofluids over a permeable stretching sheet. The study considers three types of nanoparticles-aluminum oxide (Al₂O₃), copper (Cu), and titanium oxide (TiO₂)-dispersed in a base fluid of ethylene glycol (C₂H₆O₂). This ternary hybrid nanofluid (Al₂O₃-Cu-TiO₂/C₂H₆O₂) has potential applications in cooling systems, biomedical uses for targeted drug delivery and hyperthermia treatments, heat exchangers, and polymer processing techniques like extrusion and casting.</p><p><strong>Methods: </strong>This study will examine the combined effects of Weissenberg number, power law index, nanoparticle volume fraction, viscous dissipation, magnetic field, heat generation, nonlinear thermal radiation, temperature ratio, Joule heating, Brownian motion, thermophoresis, porous permeability, variable thermal conductivity, Eckert number, Prandtl number, Schmidt number, chemical reaction, velocity ratio, and Forchheimer number on the electrical conductivity of unsteady flow in tangent hyperbolic ternary hybrid nanofluids. The governing equations are transformed into similarity equations using appropriate transformations and solved numerically with the MATLAB BVP5C package. The results are validated against data from published articles to ensure reproducibility.</p><p><strong>Results: </strong>The findings reveal that an increase in the Weissenberg and Forchheimer numbers reduces the velocity profile, while the temperature distribution increases. The variable thermal conductivity parameter (Γ) leads to a higher temperature profile, indicating improved heat transfer. Higher nanoparticle concentrations in the nanofluids and hybrid nanofluids result in enhanced skin friction, Nusselt number, and Sherwood number. Ternary hybrid nanofluids show the most significant improvement in heat transfer and thermal conductivity.</p><p><strong>Conclusions: </strong>Ternary hybrid nanofluids significantly enhance heat and mass transfer, showing potential for applications in cooling systems, drug delivery, and polymer processing. The numerical results are consistent with previous research, confirming the reliability and reproducibility of the findings.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"152"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11897691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: Total intragastric mesh migration six years after diaphragmatic rupture and hiatal hernia surgery.","authors":"Asma Sghaier, Mohamed Amine Elghali, Abdelrahmen Daadoucha, Amal Letaief, Itimed Gharbi, Fehmi Hamila, Sabri Youssef","doi":"10.12688/f1000research.139090.2","DOIUrl":"10.12688/f1000research.139090.2","url":null,"abstract":"<p><strong>Background: </strong>Mesh implementation to repair the hiatal space is already justified. Nevertheless, the use of this procedure is debated in regard of complications that may occur. Mesh erosion and migration are considered the most serious complications of mesh repairs.</p><p><strong>Case presentation: </strong>It has not yet been well described in the literature. We describe a case of mesh erosion of stomach, many years later after a prosthetic repair of a diaphragmatic rupture associated to hiatal hernia, is presented here because of its rarity.</p><p><strong>Conclusion: </strong>Few explanations have been put forward to explain this incident. Could it be due to inflammatory processes, or to the composition of the Meshes? As yet, there is no definitive explanation.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"12 ","pages":"871"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11904395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment to determine the accuracy of Chaillet and Demirjian method of dental age estimation using Orthopantomographs, Eastern Province, Saudi Arabia.","authors":"Faraz Mohammed, Arishiya Thapasum Fairozekhan, Intisar Ahmad Siddiqui, Saud AlMoumen, Turki Ali AlShehri, Maria Hassan AlRssasi, Abdullah Amer AlJami, Doha Mohsen AlRamadan, Ashwin C Shetty, Majed Mohammed Alfarea, Omar Suhaym, Nasser S AlShahrani","doi":"10.12688/f1000research.157275.2","DOIUrl":"10.12688/f1000research.157275.2","url":null,"abstract":"<p><strong>Background: </strong>The approach to estimating mandibular age has been widely used, although it has shown age estimation disparities in diverse populations, including Indians.</p><p><strong>Objective: </strong>Our goal was to test the Demirjian 8-teeth approach utilizing orthopantomogram to estimate age reliably after incorporating the third molar. We also used Chaillet and Demirjian's regression equations to estimate age estimation accuracy in the Eastern Province of Saudi Arabia.</p><p><strong>Methods: </strong>The retrospective study included 196 people. Individuals were 8-24 years old. The left mandibular teeth were staged using an orthopantomographs utilizing the Demirjian 8-teeth approach. The Chaillet and Demirjian's regression models determined dental age, and statistical methods compared dental age to chronological age.</p><p><strong>Results: </strong>The gender breakdown was 49.5% male and 50.5% female. Gender did not significantly affect chronological mean age or estimated mean age (13.39±3.77 vs. 13.10±3.51, p = 0.583; 11.75±2.92 vs. 11.58±2.70, p = 0.674). Statistically substantial differences in chronological and estimated mean ages between male and female individuals (p<0.001). Out of the total participants, 31.6% had a difference in age of ±1 year, 30.6% had a difference of 1-2 years, and 37.8% had a difference of more than 2 years. Compared to chronological and estimated ages, these variations in age between males and females were not statistically significant (p=0.557).</p><p><strong>Conclusions: </strong>The findings of this study support the use of Demirjian's 8-teeth approach in the Saudi population residing in the Eastern Province of the Kingdom of Saudi Arabia, employing Chaillet and Demirjian's regression equations.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1554"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vancomycin Population Pharmacokinetic Models in Non- Critically Ill Adults Patients: a scoping review.","authors":"Diego Nivia, Juan-David Vivas, Wilson Briceño, Daniel Parra, Manuel Mena, Diego Jaimes, Juan-Francisco Guevara, Rosa Helena Bustos","doi":"10.12688/f1000research.128260.2","DOIUrl":"10.12688/f1000research.128260.2","url":null,"abstract":"<p><strong>Background: </strong>Vancomycin is an effective first-line therapy primarily in methicillin-resistant Staphylococcus aureus (MRSA) infection and Clostridium difficile, however, it has been shown that its effectiveness and the reduction of nephrotoxicity depend on maintaining adequate therapeutic levels. Population pharmacokinetic (PopPk) models attempt to parameterize the behavior of plasma concentrations in different target populations and scenarios such as renal replacement therapy, to successful therapeutic outcome and avoid these side effects.</p><p><strong>Methods: </strong>A scoping review was conducted following the guidelines of Preferred Reporting Items for Systematic reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR), through a search in PubMed, LILACS, OVID Medline, Scopus, Web of Science, SAGE Journals, Google Scholar and previous known registers of PopPk models in non-critically ill adult patients, published between 1998 and 2024.</p><p><strong>Results: </strong>A total of 190 papers were fully screened, of which were included 36 studies conducted in different populations; 12 in general population, 23 in special populations (surgical, with impaired renal function, obese, elderly, with cancer and cystic fibrosis), and 1 in mixed population (general and with cancer). The main parameters in the models were renal clearance and volume of distribution. The principal covariables that affected the models were creatinine clearance and weight. All studies used internal evaluation and 4 of them used an external group.</p><p><strong>Discussion: </strong>The technology for the development and implementation of PopPk models requires experts in clinical pharmacology and is limited to university and research centers. The software is mostly expensive and, in most cases, the pharmacokinetic models and the heterogeneity in the parameters and evaluation methods depend on which compartmental model, parameters, covariates and software have been used.</p><p><strong>Conclusions: </strong>These models require validation in the clinical context and conducting experiments to adapt them for precision dosing in different subpopulations.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"11 ","pages":"1513"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11928783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complications following miniplate insertion in maxillofacial fractures: a systematic review.","authors":"Bramasto Purbo Sejati, Ahmad Kusumaatmaja, Maria Goreti Widiastuti, Tetiana Haniastuti","doi":"10.12688/f1000research.159017.2","DOIUrl":"10.12688/f1000research.159017.2","url":null,"abstract":"<p><strong>Background: </strong>Maxillofacial fractures, frequently arising from road traffic incidents, falls, and acts of interpersonal aggression, are a considerable public health issue, exhibiting diverse epidemiological patterns according to demographic factors. The application of miniplates for fracture stabilization is a recognized technique, with innovative methods such as 3D plate systems emerging. Nonetheless, consequences including infections and hardware malfunctions persist. This systematic review seeks to present current evidence regarding the complications linked to miniplate placement in maxillofacial fractures over the last ten years.</p><p><strong>Methods: </strong>A systematic review was performed in accordance with PRISMA principles. Databases such as the Cochrane Library, PubMed, and Scopus were examined from September 2014 to September 2024. Studies documenting problems related to miniplate placement were included, without language constraints. The ROBINS-I tool was utilized for non-randomized studies, whereas the Cochrane risk of bias tool was applied to randomized controlled trials.</p><p><strong>Results: </strong>From 2,289 initially found studies, 56 satisfied the inclusion criteria. Among these, 28 employed interventional designs, whilst the remaining 28 were observational research. The predominant problems documented in several investigations encompassed infection, wound dehiscence, malocclusion, paraesthesia, malunion/non-union, segment movement, hardware failure, and palpable hardware. Advanced methodologies such as 3D plate systems and locking mechanisms were linked to diminished complication rates.</p><p><strong>Conclusion: </strong>This systematic analysis presents a decade of updated research about problems associated with miniplate placement in maxillofacial fractures. Novel methodologies such as 3D plate systems and locking mechanisms demonstrate promise in mitigating problems relative to conventional techniques. These findings can facilitate informed decision-making in clinical practice. Additional study utilizing standardized outcomes and prospective designs is essential to enhance comprehension of the long-term effects of miniplate utilization.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1507"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring life satisfaction of self-help groups: Role of perceived social support and social empowerment.","authors":"Suraksha Suvarna, Satish Kumar, Navin Kumar Koodamara","doi":"10.12688/f1000research.148209.2","DOIUrl":"10.12688/f1000research.148209.2","url":null,"abstract":"<p><strong>Background: </strong>This study was designed to investigate the mediation effects of social empowerment (SE) in the relationship between perceived social support (PSS) and life satisfaction (LS) in women self-help group members. Also, this research attempted to understand the moderating effect of decision making (DM) and external communication (EC) on the relationship between the constructs.</p><p><strong>Methods: </strong>To achieve the above objective, the primary data were collected from the self-help group women members by using an existing scale. In this survey, 333 participants who are members of self-help group completed the questionnaire and considered for the study. The study is non-experimental and survey-based, with no interventions or manipulations involved. In line with ethical guidelines, we obtained informed consent directly from each respondent before their participation.</p><p><strong>Conclusion: </strong>The path coefficient values, t-statistics and P-Values confirmed the positive relationship between PSS->LS; PSS->SE & SE->LS in women self-group members. PLS structural equation modelling estimated by the bootstrap method revealed that SE partially mediates the relationship between PSS & LS. With regard to the interaction effect, the slope analysis and f ² effect size confirmed the moderating effect of EC in the relationship between PSS -> LS & SE -> LS.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"101"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11947657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role, function, and expectations of research funding committees: Perspectives from committee members.","authors":"Amanda Blatch-Jones, Cherish Boxall, Katie Meadmore","doi":"10.12688/f1000research.154665.2","DOIUrl":"10.12688/f1000research.154665.2","url":null,"abstract":"<p><p>Research funding committees play an integral role in the research funding process, consisting of a range of skills, knowledge, and expertise (e.g., professional, and public contributors). Although there is some evidence that has explored the efficiency and effectiveness of funding committees in terms of the funding process, there is a lack of published evidence about the purpose, role, and function of funding committees, from the perspective of committee members. A subset of survey data from a cohort of six National Institute for Health and Care Research (NIHR) research programmes, exploring the purpose of a funding committee, and the expectations and role of a funding committee member between October 2020 to December 2021. All committee members were eligible to participate in the survey. Using an inductive approach, 50 completed responses (22.5% response rate) were analysed, focusing on the role of a funding committee member and the functions of a funding committee. Participants highlighted seven key areas for the purpose of a funding committee: prioritising and recommending what research to fund (n=36) and assessment of quality (n=24) being the most common responses. Four areas were considered important to the expectations and role of funding committee members, with reviewing, critically appraising, and discussing applications (n=44); and being fair, objective, and unbiased (n=27) being the most common responses. The findings offer a unique insight into committee members' expectations about the role, purpose and function of a funding committee and their contribution to the funding recommendation process. There was high agreement that the purpose and role of committees and their members was to offer expert advice to make fair, impartial decisions on which research should be prioritised. Exploring the purpose, role, and function of funding committees has relevance and importance for funding organisations seeking to enhance and optimise the decision-making practice of funding committees.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1066"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11826072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}