Experimental Aging Research最新文献_第7页

Working Memory Precision and Associative Binding in Mild Cognitive Impairment. 轻度认知障碍患者的工作记忆精确度和联想结合力。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-03-01 Epub Date: 2023-02-08 DOI: 10.1080/0361073X.2023.2172949

Yajun Jia, Steven Woltering, Nicolaas E P Deutz, Mariëlle P K J Engelen, Kimberly S Coyle, Maria R Maio, Masud Husain, Zhong-Xu Liu

{"title":"Working Memory Precision and Associative Binding in Mild Cognitive Impairment.","authors":"Yajun Jia, Steven Woltering, Nicolaas E P Deutz, Mariëlle P K J Engelen, Kimberly S Coyle, Maria R Maio, Masud Husain, Zhong-Xu Liu","doi":"10.1080/0361073X.2023.2172949","DOIUrl":"10.1080/0361073X.2023.2172949","url":null,"abstract":"To better understand working memory (WM) deficits in Mild Cognitive Impairment (MCI), we examined information precision and associative binding in WM in 21 participants with MCI, compared to 16 healthy controls, using an item-location delayed reproduction task. WM, along with other executive functions (i.e. Trail Making Task (TMT) and Stroop task), were measured before and after a 2-h nap. The napping manipulation was intended as an exploratory element to this study exploring potential impacts of napping on executive functions.Compared to healthy participants, participants with MCI exhibited inferior performance not only in identifying encoded WM items but also on item-location associative binding and location precision even when only one item was involved. We also found changes on TMT and Stroop tasks in MCI, reflecting inferior attention and inhibitory control. Post-napping performance improved in most of these WM and other executive measures, both in MCI and their healthy peers.Our study shows that associative binding and WM precision can reliably differentiate MCIs from their healthy peers. Additionally, most measures showed no differential effect of group pre- and post-napping. These findings may contribute to better understanding cognitive deficits in MCI therefore improving the diagnosis of MCI.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10676842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship Between Habitual Use and Degree of Emotion Regulation: Age Differences in Cognitive Reappraisal and Expressive Suppression. 习惯性使用与情绪调节程度之间的关系：认知重估和表达抑制的年龄差异

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-02-19 DOI: 10.1080/0361073X.2024.2315917

Kei Oriyama, Kyoko Mukai, Kazuhiro Harada, Kouhei Masumoto

{"title":"Relationship Between Habitual Use and Degree of Emotion Regulation: Age Differences in Cognitive Reappraisal and Expressive Suppression.","authors":"Kei Oriyama, Kyoko Mukai, Kazuhiro Harada, Kouhei Masumoto","doi":"10.1080/0361073X.2024.2315917","DOIUrl":"https://doi.org/10.1080/0361073X.2024.2315917","url":null,"abstract":"Background: The present study examined age differences in and the relationship between two indices of cognitive reappraisal and expressive suppression: the degree of emotion regulation and the habitual use of emotion-regulation strategies.Method: In total, 101 younger and 99 older participants were included in this study. The degree of emotion regulation was measured using an experimental task in which participants were presented with negative or positive pictures and required to regulate their emotions. Habitual use of emotion regulation strategies was measured using an emotion regulation questionnaire.Results: The results showed that younger adults regulated their emotions to a greater extent than older adults in both reappraisal and suppression. Younger adults were more likely to use reappraisal than were older adults, although there were no age differences in the use of suppression. No significant correlations were found between the degree of emotion regulation and the habitual use of emotion regulation strategies.Conclusion: These results suggest that age differences in emotion regulation depend on the regulation strategy and that the degree of emotion regulation and habitual use of emotion regulation strategies are independent and quite different indicators in nature.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139899606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hippocampal Subregions Volume and Texture for the Diagnosis of Mild Cognitive Impairment. 用于诊断轻度认知障碍的海马亚区体积和纹理。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-02-15 DOI: 10.1080/0361073X.2024.2313940

Tongpeng Chu, Yajun Liu, Bin Gui, Zhongsheng Zhang, Gang Zhang, Fanghui Dong, Jianli Dong, Shujuan Lin

{"title":"Hippocampal Subregions Volume and Texture for the Diagnosis of Mild Cognitive Impairment.","authors":"Tongpeng Chu, Yajun Liu, Bin Gui, Zhongsheng Zhang, Gang Zhang, Fanghui Dong, Jianli Dong, Shujuan Lin","doi":"10.1080/0361073X.2024.2313940","DOIUrl":"https://doi.org/10.1080/0361073X.2024.2313940","url":null,"abstract":"The aim was to examine the diagnostic efficacy of hippocampal subregions volume and texture in differentiating amnestic mild cognitive impairment (MCI) from normal aging changes. Ninety MCI subjects and eighty-eight well-matched healthy controls (HCs) were selected. Twelve hippocampal subregions volume and texture features were extracted using Freesurfer and MaZda based on T1 weighted MRI. Then, two-sample t-test and Least Absolute Shrinkage and Selection Operator (LASSO) regression were developed to select a subset of the original features. Support vector machine (SVM) was used to perform the classification task and the area under the curve (AUC), sensitivity, specificity and accuracy were calculated to evaluate the diagnostic efficacy of the model. The volume features with high discriminative power were mainly located in the bilateral CA1 and CA4, while texture feature were gray-level non-uniformity, run length non-uniformity and fraction. Our model based on hippocampal subregions volume and texture features achieved better classification performance with an AUC of 0.90. The volume and texture of hippocampal subregions can be utilized for the diagnosis of MCI. Moreover, we found that the features that contributed most to the model were mainly textural features, followed by volume. These results may guide future studies using structural scans to classify patients with MCI.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139734803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining the Utility of a Multiple Group Membership Intervention for Alleviating the Effects of Age-Based Stereotype Threat on Older adults' Memory Performance. 研究多重群体成员干预对减轻年龄刻板印象威胁对老年人记忆力影响的作用。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-01-26 DOI: 10.1080/0361073X.2024.2306457

Giverny J Parker, Catherine Haslam, Jaimee Stuart, David H K Shum, Tamara Ownsworth

{"title":"Examining the Utility of a Multiple Group Membership Intervention for Alleviating the Effects of Age-Based Stereotype Threat on Older adults' Memory Performance.","authors":"Giverny J Parker, Catherine Haslam, Jaimee Stuart, David H K Shum, Tamara Ownsworth","doi":"10.1080/0361073X.2024.2306457","DOIUrl":"https://doi.org/10.1080/0361073X.2024.2306457","url":null,"abstract":"This study examined the effectiveness of a multiple group membership intervention for reducing the negative effects of age-based stereotype threat (ABST) on older adults' objective memory performance and subjective memory concerns. Healthy older adults (N = 68) were randomly allocated to an ABST + threat-removal (ABST+TR) or ABST + active-control (ABST+AC) condition. After activating ABST, the ABST+TR condition completed a group-listing task and the ABST+AC condition completed a meal-listing task. Participants then completed the Rey Auditory Verbal Learning Test (RAVLT) and Everyday Memory Questionnaire - Revised. One significant difference was found in memory performance between conditions; specifically, after controlling for age, gender, and number of items listed, those in the ABST+TR condition performed significantly better on the RAVLT memory interference trial. Further, listing a greater number of group memberships was associated with better memory performance in the ABST+TR condition. No significant difference was found in subjective memory concerns between the ABST+TR condition and the ABST+AC condition. Overall, the current findings indicated that raising the salience of multiple group memberships offered limited protection for older adults' cognitive test performance in the context of ABST.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139566943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Music-Evoked Autobiographical Memories are Associated with Negative Affect in Younger and Older Adults 音乐诱发的自传体记忆与年轻人和老年人的负面情绪有关

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-01-13 DOI: 10.1080/0361073x.2024.2302785

Kendra Mehl, Alaine E. Reschke-Hernandez, Julien Hanson, Lauren Linhardt, Jessica Frame, Matthew Dew, Elizabeth Kickbusch, Chase Johnson, Elena Bai, Amy M. Belfi

引用次数: 0

Association Between Body Mass Index and Cognitive Function Among Older Adults in India: Findings from a Cross-Sectional Study. 印度老年人身体质量指数与认知功能之间的关系：一项横断面研究的结果。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-01-01 Epub Date: 2023-01-26 DOI: 10.1080/0361073X.2023.2171686

Alok Roy

{"title":"Association Between Body Mass Index and Cognitive Function Among Older Adults in India: Findings from a Cross-Sectional Study.","authors":"Alok Roy","doi":"10.1080/0361073X.2023.2171686","DOIUrl":"10.1080/0361073X.2023.2171686","url":null,"abstract":"Objective: The study aimed to explore the association between body mass index (BMI) and cognitive function among older adults in India.Methods: Cross-sectional data on 21,000 older adults aged 60 years and older from the first wave of the Longitudinal Ageing Study of India (LASI), conducted in India during 2017-18, were used. Bivariate analysis and multivariate linear regression models were applied. The cognition tests include memory, orientation, arithmetic function, executive function, and object naming.Results: The mean overall cognition score was 24.6 in the study population. Further, BMI status showed a significant and positive association with cognition. The association of underweight with poor cognition (β=-0.72; 95% CI = -0.89, -0.54) whereas overweight (β = 0.57; 95% CI = 0.39, 0.75) and obese (β = 0.97; 95% CI = 0.68, 1.26) with better cognition remained statistically significant after adjusting for sociodemographic, health-related behavior, and health covariates. The mean cognition score of female older adults was always lower than male older adults with normal BMI, irrespective of their BMI categories.Conclusions: This study shows that an underweight BMI is associated with poor cognition in both male and female older adults. In the context of providing health care for older individuals, underweight individuals should be given more attention in India.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10623688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Age and Gender Differences in the Borrowing of Personal Stories. 借用个人故事时的年龄和性别差异。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-01-01 Epub Date: 2023-01-29 DOI: 10.1080/0361073X.2023.2168441

Jessica Udry, Jessica Becerra, Hyunji Kim, Sarah J Barber

引用次数: 0

Cognitive Performance following Single- or Multi-Session Exercise Intervention in Middle Age: A Systematic Review. 中年人单次或多次运动干预后的认知表现：系统回顾

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-01-01 Epub Date: 2022-11-17 DOI: 10.1080/0361073X.2022.2137360

Fayeza S Ahmed, Taylor M McMillan, Benjamin A Guenther, Peter Dearborn

{"title":"Cognitive Performance following Single- or Multi-Session Exercise Intervention in Middle Age: A Systematic Review.","authors":"Fayeza S Ahmed, Taylor M McMillan, Benjamin A Guenther, Peter Dearborn","doi":"10.1080/0361073X.2022.2137360","DOIUrl":"10.1080/0361073X.2022.2137360","url":null,"abstract":"Background: Research in modifiable behaviors, like exercise, on risk for dementia is increasing. Although many studies focus on older adults, brain pathology for Alzheimer's Disease can begin in middle age, suggesting an ideal target for intervention.Methods: We conducted a systematic review from exercise intervention studies on cognitive function among healthy, middle-aged participants (45-65). We searched multiple databases (PubMed, PsycINFO, MEDLINE, Cochrane Central Register of Controlled Trials, Google Scholar) for studies using standard, validated, neuropsychological measures following either single- or multi-session interventions in cognitively-unimpaired, middle-aged adults.Results: We identified 13 eligible studies. There was notable heterogeneity across studies, with varying design, measures, interventions, and results. Results from single-session studies showed improvement in response inhibition, while results for cognitive flexibility were mixed. No significant changes were found on measures of attention, working memory, or processing speed. Results from multi-session studies were more varied. Verbal memory was found to improve while performance on tests of attention and working memory, processing speed, and executive function were mixed.Conclusion: Importantly, for both single-session and multi-session studies, there was no standard set of neuropsychological tests administered, making it more difficult to synthesize the findings into a single narrative. We end with a discussion on future directions and implementation.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40687859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Olfactory Dysfunction Associated with Cognitive Decline in an Elderly Population. 与老年人认知能力下降有关的嗅觉功能障碍

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-01-01 Epub Date: 2022-12-22 DOI: 10.1080/0361073X.2022.2160597

Majed Alotaibi, Melissa Lessard-Beaudoin, Kate Busch, Amal Loudghi, Pierrette Gaudreau, Rona K Graham

{"title":"Olfactory Dysfunction Associated with Cognitive Decline in an Elderly Population.","authors":"Majed Alotaibi, Melissa Lessard-Beaudoin, Kate Busch, Amal Loudghi, Pierrette Gaudreau, Rona K Graham","doi":"10.1080/0361073X.2022.2160597","DOIUrl":"10.1080/0361073X.2022.2160597","url":null,"abstract":"Background: In many neurological disorders, including Alzheimer disease, early olfactory dysfunction is observed.Objective: In order to determine if deficits in olfactory memory are present in the elderly and if olfactory dysfunction correlates with cognitive impairment in the aging population, olfactory testing has been done on seniors from the NuAge cohort accepting to participate in the Olfactory Response Cognition and Aging (ORCA) secondary sub-study. The t-Mini Mental Statement Examination and the Telephone Interview for Cognitive Status tests were done to assess cognition levels.Results: Overall, 94% of the ORCA cohort displayed olfactory dysfunction. Deficits in olfactory memory were also present. A correlation was observed between olfactory function and cognitive test scores. Moreover, in women who smoked, there was an association between olfactory memory and cognitive scores.Conclusion: Our results suggest that olfactory dysfunction may predict impending cognitive decline and highlights the need for olfactory training in seniors to improve olfaction and overall well-being.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10474812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Age Differences in Gaze Following: Older Adults Follow Gaze More than Younger Adults When free-viewing Scenes. 目光追随的年龄差异：在自由观看场景时，老年人比年轻人更关注目光。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-01-01 Epub Date: 2022-12-26 DOI: 10.1080/0361073X.2022.2156760

Eunice G Fernandes, Benjamin W Tatler, Gillian Slessor, Louise H Phillips

引用次数: 0