Experimental Aging Research最新文献_第7页

The Combined Effect of Tribulus terrestris Hydroalcoholic Extract and Swimming Exercise on Memory and Oxidative Stress in Old Male Rats. 刺蒺藜水醇提取物和游泳运动对老年雄性大鼠记忆力和氧化应激的联合影响

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-07-29 DOI: 10.1080/0361073X.2024.2377432

Zinat Heydarnia Kalati, Hossein Harati, Seyed-Hosein Abtahi-Eivary, Mohammad Javad Dehestany Zarch, Younes Karami, Maryam Moghimian, Masoumeh Fani

{"title":"The Combined Effect of Tribulus terrestris Hydroalcoholic Extract and Swimming Exercise on Memory and Oxidative Stress in Old Male Rats.","authors":"Zinat Heydarnia Kalati, Hossein Harati, Seyed-Hosein Abtahi-Eivary, Mohammad Javad Dehestany Zarch, Younes Karami, Maryam Moghimian, Masoumeh Fani","doi":"10.1080/0361073X.2024.2377432","DOIUrl":"https://doi.org/10.1080/0361073X.2024.2377432","url":null,"abstract":"Background and objective: This study aims to assess the effect of swim exercise along with consumption of bindii hydroalcoholic extract on memory and the oxidative stress markers in old male rats.Materials and methods: This study was conducted on 32 old (400-500 g) and eight young male Wistar rats. The groups included young, old, old bindii (200 mg/kg), old exercise, and old bindii exercise (concurrent swimming training). All interventions were performed within 14 days. The animals' spatial memory was evaluated by the Y maze, radial maze, and shuttle box, Oxidative stress factors were also measured.Results: Compared to the old control group, the bindii extract along with swimming exercise significantly increased the periodic behavior percentage in the Y maze and the delay time in entry into the dark chamber in the shuttle box but no significant difference was seen in the reference memory error in the radial maze. Also, a significant increase in the amount of catalase (CAT) and antioxidant capacity (TAC) and a significant decrease in the amount of malondialdehyde (MDA) were observed in all treatment groups.Conclusion: These results show that exercise, along with the bindii extract consumption, can improve spatial and avoidance memory in old rats probably through the reduction of oxidative stress effects.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-15"},"PeriodicalIF":1.4,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mediating Role of Psychological Status in the Association Between Resiliency and Quality of Life Among Older Malaysians Living with Knee Osteoarthritis. 心理状态在患有膝关节骨关节炎的马来西亚老年人的复原力与生活质量之间的关联中的中介作用。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-07-18 DOI: 10.1080/0361073X.2024.2377436

Siti Sarah Norman, Sumaiyah Mat, Siti Salwana Kamsan, Sawal Hamid Md Ali, Nor Hamdan Mohamad Yahaya, Caryn Chan Mei Hsien, Dayang Balkis Md Ramli, Noorlaili Mohd Tohit, Norhayati Ibrahim, Suzana Shahar

{"title":"Mediating Role of Psychological Status in the Association Between Resiliency and Quality of Life Among Older Malaysians Living with Knee Osteoarthritis.","authors":"Siti Sarah Norman, Sumaiyah Mat, Siti Salwana Kamsan, Sawal Hamid Md Ali, Nor Hamdan Mohamad Yahaya, Caryn Chan Mei Hsien, Dayang Balkis Md Ramli, Noorlaili Mohd Tohit, Norhayati Ibrahim, Suzana Shahar","doi":"10.1080/0361073X.2024.2377436","DOIUrl":"https://doi.org/10.1080/0361073X.2024.2377436","url":null,"abstract":"Resilience increases the ability of an individual to overcome adversity. It has not yet been determined how resilience is linked to quality of life among individuals experiencing knee osteoarthritis symptoms. To explore the inter-relationships of psychological distress, resilience and quality of life among older individuals with knee osteoarthritis. The study examined older adults in Kuala Lumpur and Selangor, identifying osteoarthritis through verified physician diagnosis. Various factors, including resilience, psychological status, and quality of life, were measured. In the study with 338 older adults, 50.9% had knee osteoarthritis. Higher resilience was linked to lower depression, anxiety, and stress, and better quality of life in both groups with and without knee osteoarthritis. Psychological factors consistently mediated the link between resilience and quality of life even after controlling potential confounders. Analysis showed that depression, anxiety, and stress mediate the relationship between resilience and quality of life, indicating a significant influence even when considering various factors. Resilience appears to influence psychological well-being and quality of life among older adult with knee osteoarthritis.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-14"},"PeriodicalIF":1.4,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the Effect of Tai Chi Training on Depressive Symptoms in Perimenopausal Women on the Basis of Serum Kynurenine Metabolites. 基于血清犬尿氨酸代谢物研究太极拳训练对围绝经期妇女抑郁症状的影响

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-07-18 DOI: 10.1080/0361073X.2024.2377427

Jing Liu, Jingmei Si, Weiwei Zhao

{"title":"Investigation of the Effect of Tai Chi Training on Depressive Symptoms in Perimenopausal Women on the Basis of Serum Kynurenine Metabolites.","authors":"Jing Liu, Jingmei Si, Weiwei Zhao","doi":"10.1080/0361073X.2024.2377427","DOIUrl":"https://doi.org/10.1080/0361073X.2024.2377427","url":null,"abstract":"Objective: To observe the effects of Tai Chi training on depression symptoms and serum kynurenine metabolites in perimenopausal women and explore the mechanism of Tai Chi training in anti-depression.Methods: A total of 72 perimenopausal women with depression were randomly selected from Lishi District and divided into a Tai Chi training group (36 cases) and a control group (36 cases). At the same time, 36 perimenopausal healthy women were randomly selected as the normal group. The Tai Chi training group was intervened with 24 simplified Tai Chi exercises, and the depression self-rating scale was used to evaluate the depression status. The levels of tryptophan (Trp) and kynurenine (KYN) metabolites in serum were determined by high-performance liquid chromatography-ultraviolet detection.Results: Before the experiment, compared with the normal healthy group, the depression self-rating scale scores, serum KYN and quinolinic acid (QUIN) levels, and KYN/Trp ratio of the control group and Tai Chi group were significantly increased (p < .01), and the serum kynurenic acid (KYNA) level was significantly decreased (p < .01). After the experiment, compared with the normal healthy group, the depression self-rating scale scores of the Tai Chi group were significantly decreased (p < .01), the serum KYNA content was increased (p < .01), the serum KYN and QUIN contents were significantly decreased (p < .01), and the KYN/Trp ratio was significantly decreased (p < .01).Conclusion: Tai Chi training can significantly improve depression symptoms in perimenopausal women. The mechanism of Tai Chi training in improving depression symptoms in perimenopausal women may be achieved by regulating abnormal kynurenine metabolism.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-19"},"PeriodicalIF":1.4,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emotional State of Older Adults During the COVID-19 Pandemic: Insights from the Cognitive and Social Well-Being (CoSoWELL) Corpus. COVID-19 大流行期间老年人的情绪状态：从认知和社会福祉（CoSoWELL）语料库中获得的启示》（Emotional State of Older Adults During the COVID-19 Pandemic: Insights from the Cognitive and Social Well-Being (CoSoWELL) Corpus.

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-07-01 Epub Date: 2023-06-04 DOI: 10.1080/0361073X.2023.2219188

Aki-Juhani Kyröläinen, Victor Kuperman

{"title":"Emotional State of Older Adults During the COVID-19 Pandemic: Insights from the Cognitive and Social Well-Being (CoSoWELL) Corpus.","authors":"Aki-Juhani Kyröläinen, Victor Kuperman","doi":"10.1080/0361073X.2023.2219188","DOIUrl":"10.1080/0361073X.2023.2219188","url":null,"abstract":"Objectives: In view of the fallout of the COVID-19 pandemic, psychologists face a challenge to document the pandemic-related change in emotional well-being of individuals and groups and evaluate the emotional response to this fallout over time.Methodsp: We contribute to this goal by analyzing the new CoSoWELL corpus (version 2.0), an 1.8 million-word collection of narratives written by over 1,300 older adults (55+ y.o.) in eight sessions before, during and after the global lockdown. In the narratives, we examined a range of linguistic variables traditionally associated with emotional well-being and observed signs of distress, i.e., lower positivity and heightened levels of fear, anger, and disgust.Results: In most variables, we observed a characteristic timeline of change, i.e., a delayed (by 4 months) and abrupt drop in optimism and increase in negative emotions that reached its peak about 7 months after the lockdown and returned to pre-pandemic levels one year after. Our examination of risk factors showed that higher levels of self-reported loneliness came with elevated levels of negative emotions but did not change the timeline of emotional response to the pandemic.Conclusions: We discuss implications of the findings for theories of emotion regulation.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"482-505"},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9574532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Secular Changes in Masters Swimming Performances: A 40-Year Follow Up. 游泳大师成绩的周期性变化：40 年的跟踪研究。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-07-01 Epub Date: 2023-07-06 DOI: 10.1080/0361073X.2023.2233367

Alan A Hartley, Joellen T Hartley

引用次数: 0

Absent Relations of Religious Coping to Telomere Length in African American and White Women and Men. 非裔美国人和白人女性和男性的宗教应对与端粒长度没有关系。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-07-01 Epub Date: 2023-05-31 DOI: 10.1080/0361073X.2023.2219187

Jason J Ashe, Michele K Evans, Alan B Zonderman, Shari R Waldstein

{"title":"Absent Relations of Religious Coping to Telomere Length in African American and White Women and Men.","authors":"Jason J Ashe, Michele K Evans, Alan B Zonderman, Shari R Waldstein","doi":"10.1080/0361073X.2023.2219187","DOIUrl":"10.1080/0361073X.2023.2219187","url":null,"abstract":"Objectives: This study investigated whether race and sex moderated the relations of religious coping to telomere length (TL), a biomarker of cellular aging implicated in race-related health disparities.Methods: Participant data were drawn from the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study, which included 252 socioeconomically diverse African American and White men and women aged (30-64 years old). Cross-sectional multivariable regression analyses examined interactive associations of religious coping, race, and sex to TL, adjusting for other sociodemographic characteristics.Results: Religious coping was unrelated to TL in this sample (p's > .05). There were no notable race or sex differences. Post hoc exploratory analyses similarly found that neither secular social support coping use nor substance use coping was associated with TL.Conclusion: There was no evidence to support that religious coping use provided protective effects to TL in this sample of African American and White women and men. Nevertheless, future studies should use more comprehensive assessments of religious coping and intersectional identities to provide an in-depth examination of religiosity/spirituality as a potential culturally salient protective factor in cellular aging among African Americans in the context of specific chronic stressors such as discrimination.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"459-481"},"PeriodicalIF":1.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9553295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Semantic Priming from Uncued Distractors in Alzheimer's Disease. 阿尔茨海默氏症患者从未预见到的分词中获得语义引物

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-07-01 Epub Date: 2023-04-23 DOI: 10.1080/0361073X.2023.2195294

Julie A Higgins, William Milberg, Regina McGlinchey

引用次数: 0

Effects of Ocimum basilicum L. Extract on Hippocampal Oxidative Stress, Inflammation, and BDNF Expression in Amnesic Aged Rats. 欧鼠李提取物对失忆老年大鼠海马氧化应激、炎症和BDNF表达的影响

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-07-01 Epub Date: 2023-05-08 DOI: 10.1080/0361073X.2023.2210240

Farimah Beheshti, Arefeh Vakilian, Mohsen Navari, Mostafa Zare Moghaddam, Hossein Dinpanah, S Mohammad Ahmadi-Soleimani

{"title":"Effects of Ocimum basilicum L. Extract on Hippocampal Oxidative Stress, Inflammation, and BDNF Expression in Amnesic Aged Rats.","authors":"Farimah Beheshti, Arefeh Vakilian, Mohsen Navari, Mostafa Zare Moghaddam, Hossein Dinpanah, S Mohammad Ahmadi-Soleimani","doi":"10.1080/0361073X.2023.2210240","DOIUrl":"10.1080/0361073X.2023.2210240","url":null,"abstract":"The present study was conducted to investigate the effects of Ocimum basilicum L. (OB) extract on learning and memory impairment in aged rats. Male rats were divided into the following experimental groups: Group 1 (control): including 2 months old rats, Group 2 (aged) including 2 years old rats, Groups 3-5 (aged-OB): including 2 years old rats received 50, 100, and 150 mg/kg OB for 8 weeks by oral gavage. Aging increased the delay to find the platform but, however, decreased the time spent in the target quadrant when tested by Morris water maze (MWM). Aging also reduced the latency to enter the dark chamber in the passive avoidance (PA) test compared to the control group. Moreover, interleukin-6 (IL-6) and malondialdehyde (MDA) levels were raised in the hippocampus and cortex of aged rats. In contrast, thiol levels and enzymatic activity of superoxide dismutase (SOD) and catalase (CAT) significantly reduced. In addition, aging significantly reduced BDNF expression. Finally, OB administration reversed the mentioned effects. The current research showed that OB administration improves learning/memory impairment induced by aging. It also found that this plant extract protects the brain tissues from oxidative damage and neuroinflammation.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"443-458"},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9784655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring Effects of Age on Conflict Processing in the Light of Practice in a Large-Scale Dataset. 从大规模数据集的实践角度探讨年龄对冲突处理的影响。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-07-01 Epub Date: 2023-05-31 DOI: 10.1080/0361073X.2023.2214051

Fabiola Reiber, Rolf Ulrich

{"title":"Exploring Effects of Age on Conflict Processing in the Light of Practice in a Large-Scale Dataset.","authors":"Fabiola Reiber, Rolf Ulrich","doi":"10.1080/0361073X.2023.2214051","DOIUrl":"10.1080/0361073X.2023.2214051","url":null,"abstract":"Introduction: The possible decline of cognitive functions with age has been in the focus of cognitive research in the last decades. The present study investigated effects of aging on conflict processing in a big dataset of a Stroop-inspired online training task.Methods: We focused on the temporal dynamics of conflict processing in the light of task practice by means of inspecting delta plots and Lorenz-interference curves to gain insights on a process level.Results: The results indicate a relatively constant increase of cognitive conflict over the course of adulthood and a decrease with practice. Furthermore, the latency of the automatic processing of conflicting information relative to the controlled processing of task-relevant information decreases relatively constantly with age. This effect is moderated by practice, that is, the relative latency of the automatic processing decreases less with age at high practice levels.Conclusion: As such, practice seems to be able to partially counteract age-related differences in conflict processing, on a process level.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"422-442"},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9606859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-07-01 Epub Date: 2023-07-06 DOI: 10.1080/0361073X.2023.2233366

Dillon H Murphy, Alan D Castel, Barbara J Knowlton

{"title":"Age-Related Differences in Framing Selective Memory in Terms of Gains and Losses.","authors":"Dillon H Murphy, Alan D Castel, Barbara J Knowlton","doi":"10.1080/0361073X.2023.2233366","DOIUrl":"10.1080/0361073X.2023.2233366","url":null,"abstract":"We examined whether framing younger and older adults learning goals in terms of maximizing gains or minimizing losses impacts their ability to selectively remember high-value information. Specifically, we presented younger and older adults with lists of words paired with point values and participants were either told that they would receive the value associated with each word if they recalled it on a test or that they would lose the points associated with each word if they failed to recall it on the test. We also asked participants to predict the likelihood of recalling each word to determine if younger and older adults were metacognitively aware of any potential framing effects. Results revealed that older adults expected to be more selective when their goals were framed in terms of losses, but younger adults expected to be more selective when their goals were framed in terms of gains. However, this was not the case as both younger and older adults were more selective for high-value information when their goals were framed in terms of maximizing gains compared with minimizing losses. Thus, the framing of learning goals can impact metacognitive decisions and subsequent memory in both younger and older adults.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"506-521"},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10770296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9758885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0