Experimental Aging Research最新文献

{"title":"Effects of Bioceramic Material and Colored Light Irradiation on Learning and Memory in Aging Rats.","authors":"Ting-Kai Leung, Yu-Chen Chen, Ming-Wei Chao, Chia-Yi Tseng","doi":"10.1080/0361073X.2023.2278983","DOIUrl":"https://doi.org/10.1080/0361073X.2023.2278983","url":null,"abstract":"<p><p>Aging is characterized by molecular damage from free radicals, leading to neural dysfunction and memory impairment. This study investigated using bioceramic material and colored light to mitigate neurodegenerative symptoms in aging rats. We assessed the effects of different color light spectrums on D-galactose-induced aging rats using the Morris water maze, novel object recognition, and open field tests. Findings revealed that bioceramic material with various light wavelengths improved activity, recognition, and memory in aging rats. Significant enhancements were observed in the open field and novel object recognition tests, with a trend toward improvement in the Morris water maze. These effects are attributed to the antioxidant properties and microcirculation enhancement associated with bioceramic materials. Color stimulation may impact enzymes, human physiology, psychological activity, and the autonomic nervous system. This study highlights the significance of exploring novel interventions for neurodegenerative symptoms and memory deficits in aging rats. Results indicate that bioceramic material with different colored light spectrums positively influences cognitive function. These findings contribute to our understanding of the therapeutic potential of bioceramic materials and emphasize the need for further research in this area.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136397092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Autonomy and Physical Activity on Self-Rated Health of Older Adults in India: Gendered Analysis Using Structural Equation Models.","authors":"Bevin Vijayan, Dipti Govil, Harihar Sahoo","doi":"10.1080/0361073X.2023.2278982","DOIUrl":"https://doi.org/10.1080/0361073X.2023.2278982","url":null,"abstract":"<p><p>The gendered expectations and responsibilities placed upon women can impede their ability to participate in social activities and engage in physical leisure pursuits, ultimately having a negative impact on their health. Our study investigates the mechanisms through which gender influences individuals' engagement with physical activity during free time and how this relates to self-rated health outcomes among adults aged 45 years or older living in India. Using cross-sectional analysis and Structural Equation Modelling, we analyzed data stratified by gender and age from the Longitudinal Ageing Study of India to examine these conceptual pathways. We found that compared to men, women face greater limitations related to decision-making autonomy, experience more functional impairments, have weaker social networks that provide less support for engaging in leisure-time physical activity, leading them to report lower levels of overall wellbeing than men. Further analyses demonstrated distinct pathways through which each gender's level of social network connectivity shapes behavior - strong connections increase opportunities for women specifically to engage positively with both peers and physically active pursuits supporting overall wellness goals.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89717585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does the Sensory Experience of Words Boost Recollection in Aging?","authors":"Aurélia Bugaiska, Arnaud Witt, Patrick Bonin","doi":"10.1080/0361073X.2023.2269800","DOIUrl":"https://doi.org/10.1080/0361073X.2023.2269800","url":null,"abstract":"<p><strong>Objectives: </strong>We examine age-related differences in recollection and test the impact of words with high vs low sensory experience ratings (SER) in older and younger adults. We expected that the recollection of words with high SER would be similar in older and young adults, as they depend on knowledge, unlike recollection of words with a low SER, which would depend on executive functions.</p><p><strong>Methods: </strong>We manipulated the sensory experience of words (high vs. low) in encoding in young and older adults. The participants then took a word-recognition test using the Remember/Know paradigm (Gardiner, 1988). We also evaluated executive functions using several measures.</p><p><strong>Results: </strong>Results show that the age-related difference in recollective experience was eliminated under the high SER encoding condition. Moreover, Remember (R) responses in the low SER condition seem to be related to executive functioning, unlike R responses in the high SER condition and Know (K) responses in both low and high SER conditions.</p><p><strong>Discussion: </strong>Our study shows that the memory benefit of high-SER words is greater for older than younger adults. The study also supports the observation that older adults can compensate for their deficits by using sensory experience to consciously recollect information.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72013960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age-Related Changes in the Utilization of Visual Information for Collision Prediction: A Study Using an Affordance-Based Model.","authors":"Kazuyuki Sato, Kazunobu Fukuhara, Takahiro Higuchi","doi":"10.1080/0361073X.2023.2278985","DOIUrl":"https://doi.org/10.1080/0361073X.2023.2278985","url":null,"abstract":"<p><p>The ability to predict collisions with moving objects deteriorates with aging. We followed the affordance-based model to identify optical variables that older adults had difficulty using for collision prediction. We reproduced a modified version of the interception task used in Steinmetz (Steinmetz, Layton, Powell, & Fajen, 2020, \"Affordance-based versus current - future accounts of choosing whether to pursue or abandon the chase of a moving target,\" <i>Journal of Vision</i>, 20(3), 8) in a virtual reality (VR) environment and newly introduced perturbation for each of three optical variables (vertical and horizontal expansions of a moving object and the bearing angle produced between participants and a moving object). We expected that perturbation would negatively affect the performance only for those who rely on the optical variable to perform the interception task effectively. We tested 18 older and 15 younger adults and showed that older participants were not negatively affected by the perturbation for the vertical and horizontal expansion of a moving object, while they showed decreased performance when the perturbation was introduced with a bearing angle. These findings suggest that predicting collisions with moving objects deteriorates with aging because the perception of object expansion is impaired with aging.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71520984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Perceptions of Future Time on Implicit and Explicit Memory in Older Adults.","authors":"Aurélia Bugaiska, Patrick Bonin, Julie Ferreira, Arnaud Witt","doi":"10.1080/0361073X.2023.2269801","DOIUrl":"https://doi.org/10.1080/0361073X.2023.2269801","url":null,"abstract":"<p><strong>Objectives: </strong>We examine age-related differences in implicit and explicit memory tasks, and test the impact of future time perspectives on priming and cued recall.</p><p><strong>Methods: </strong>We induced time perspective in young (limited-time perspective) and older (extended-time perspective) adults. Implicit and explicit memory tasks were performed by younger and older adults.</p><p><strong>Results: </strong>Results showed an age-related effect on priming and cued recall, confirming that implicit and explicit memory are impaired in aging. Nevertheless, manipulation of future time perspective eliminated age differences in priming and cued recall.</p><p><strong>Discussion: </strong>These findings support the view that it is not age <i>per se</i> that determines memory performance but rather the perception of the time left to us. Socio-emotional selectivity theory thus seems to be a serious candidate to explain age-related differences in implicit and explicit memory.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71479918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Interviewer Age on the Reminiscence Bump in Older adults' Autobiographical Memories.","authors":"Yoko Sakata","doi":"10.1080/0361073X.2023.2269802","DOIUrl":"https://doi.org/10.1080/0361073X.2023.2269802","url":null,"abstract":"<p><strong>Introduction: </strong>This study aims to investigate whether the reminiscence bump in older adults' autobiographical memory is influenced by the interviewer's age. Methods: I arranged four interviewer.</p><p><strong>Conditions: </strong>child, university student, middle-aged adult, and older adult. The participating older adults were asked individually to describe three memories and the age at which the event occurred. I analyzed the temporal distribution of the bumps and the recall order.</p><p><strong>Results: </strong>The results indicate that the interviewer's age, especially the child interviewers were influenced the temporal location of the reminiscence bump. Conclusion: This study discusses the implications of these findings for older adults' social communication processes.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71479919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association of Social Support, Depression, and Loneliness with Health-Related Quality of Life in Over 50 Years Adults: Ardakan Cohort Study on Ageing (ACSA).","authors":"Ahmad Delbari, Isa Akbarzadeh, Mohammad Saatchi, Fatemeh-Sadat Tabatabaei, Mohammad Bidkhori, Yadollah Abolfathi Momtaz, Reza Mohseni-Bandpey, Elham Hooshmand","doi":"10.1080/0361073X.2023.2273164","DOIUrl":"10.1080/0361073X.2023.2273164","url":null,"abstract":"<p><strong>Background and aim: </strong>Social factors play a crucial role in the quality of life of + 50 adults. This study aimed to investigate the association between social support, depression, and loneliness and the health-related quality of life in + 50 adults of Ardakan.</p><p><strong>Methods: </strong>This was a cross-sectional study from the first phase of Ardakan Cohort Study on Aging (ACSA) in 2019. Health-Related Quality of Life (HRQoL, SF-16), Duke Social Support Index (DSSI), and Center for Epidemiologic Studies Depression Scale (CES-D10) were used to assess the variables of interest. Multivariable linear regression was used to model the associated factors with the score of the SF-16 tool in two dimensions; physical (PCS) and mental (MCS).</p><p><strong>Findings: </strong>A total of 5197 over 50 years individuals included in this study; The mean age was 62.2 ± 7.3 years old, and 52% were male. The mean score for PCS and MCS subscales was 45.6 (95% CI 45.4 to 45.9) and 49.3 (95% CI 49.0 to 49.5), respectively. Adjusted for other variables, having less feeling level of loneliness, and not having depressive symptoms were related to better PCS and MCS scores.</p><p><strong>Conclusion: </strong>The HRQoL for the mental aspect of HRQoL was better than the physical in elder populations. Also, much more focus should be paid to older adults who experience inadequate social support, higher levels of loneliness, and depressive symptoms.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50161174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low 25-Hydroxyvitamin D [25(OH)D] Levels as a Predictor of Depressive Symptoms: Evidence from Community-Dwelling Older Adults Population in Mexico City.","authors":"Graciela Llanos-Becerra,&nbsp;Eduardo Dávila-Godínez,&nbsp;Norma Torres-Carrillo,&nbsp;Oscar Rosas-Carrasco,&nbsp;Elena Sandoval-Pinto,&nbsp;Raúl Beltrán-Ramírez,&nbsp;Nora Magdalena Torres-Carrillo","doi":"10.1080/0361073X.2023.2269803","DOIUrl":"https://doi.org/10.1080/0361073X.2023.2269803","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study was to assess the association between serum 25-hydroxyvitamin D [25(OH)D] levels and depressive symptoms in Mexican older adults 70 years and older.</p><p><strong>Methods: </strong>A total of 326 adults aged 70 or older from Coyoacán Cohort Study were included in this study. The depressive symptoms were assessing by Center for Epidemiologic Studies Depression Scale (CES-D) and serum 25-hydroxyvitamin D [25(OH)D] levels were measured by commercially available enzyme-linked immunosorbent assay (ELISA).</p><p><strong>Results: </strong>Overall, the prevalence of depressive symptoms was 36.5%. The mean age was 79 years, and 53.4% were women. The total serum 25-hydroxyvitamin D [25(OH)D] levels were lower in older adults with depressive symptoms when compared with older adults without depressive symptoms (<i>p</i> = .006). Logistic regression models showed a significant association between low serum 25(OH)D levels and depressive symptoms even after adjusting for potential confounders (OR = 2.453; 95% CI:1.218-4.939; <i>p</i> = .012). In addition, linear regression model to predict the effect of 25-hydroxyvitamin D [25(OH)D] levels on the CES-D score as a continuous variable, was statistically significant [F_(1,324) = 8.54, <i>p</i> = .004], and the R-squared value was .026, indicating that this regression model explains 2.6% of the change in the CES-D score.</p><p><strong>Conclusion: </strong>These results suggest that older Mexican adults with lower serum 25-hydroxyvitamin D [25(OH)D] levels are at higher risk of presenting depressive symptoms.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41196038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Older Adults Show Intraindividual Variation in the Use of Predictive Processing.","authors":"Suzanne R Jongman, Allyson Copeland, Yaqi Xu, Brennan R Payne, Kara D Federmeier","doi":"10.1080/0361073X.2022.2137358","DOIUrl":"10.1080/0361073X.2022.2137358","url":null,"abstract":"<p><strong>Background: </strong>The use of prediction can aid language comprehension through preactivation of relevant word features. However, predictions can be wrong, and it has been proposed that resolving the mismatch between the predicted and presented item requires cognitive resources. Older adults tend not to predict and instead rely more on passive comprehension. Here, we tested, using an intraindividual approach, whether older adults consistently use this less demanding processing strategy while reading or whether they attempt to predict on some trials.</p><p><strong>Methods: </strong>We used a cross-task conflict paradigm. Younger and older participants self-paced to read sentences that ended with either an expected or unexpected word. Each sentence was then followed by a flanker stimulus that could be congruent or incongruent. We examined responses within and across the two tasks.</p><p><strong>Results: </strong>Unexpected words were in general read as quickly as expected words, indicating that typical processing of these words was similar. However, for both younger and older adults, there was a greater proportion of very slow trials for unexpected words, revealing different processing on a subset of trials. Critically, in older adults, these slowly read unexpected words engaged control, as seen in speeded responses to incongruent flanker stimuli.</p><p><strong>Conclusion: </strong>Using a cross-task conflict paradigm, we showed that older adults are able to predict and engage cognitive resources to cope with prediction violations, but do not opt to use these processes consistently.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10024197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of whole-course nutrition management on accelerated recovery in elderly patients with bladder cancer","authors":"Wenwen Fu, Lina Zhang","doi":"10.26599/agr.2023.9340014","DOIUrl":"https://doi.org/10.26599/agr.2023.9340014","url":null,"abstract":"<sec><strong>Objective</strong> The purpose of this article is to explore the effect of whole-course nutrition management on accelerated recovery in elderly patients with bladder cancer. </sec><sec><strong>Results</strong> 126 elderly patients with bladder cancer completed the study (<i>N</i>_{accelerated rehabilitation} = 63; <i>N</i>_control = 63). The levels of albumin, prealbumin, and hemoglobin accelerated rehabilitation group were significantly higher than those in control group (<i>P</i> < 0.05), the albumin supplementation amount, intensive care unit (ICU) monitoring time, and hospitalization cost in the accelerated rehabilitation group were lower than those in the control group, with statistically significant differences (<i>P</i> < 0.05). The postoperative complication rate of patients in the accelerated rehabilitation group was lower than that of the control group. There was no significant difference between the two groups in body composition body mass index (BMI), actual weight, body fat volume, body fat percentage, fat free weight, visceral fat area Basal metabolic rate, ratio of total body water to protein weight, waist circumference, phase angle (<i>P</i> > 0.05), The degree of loss of skeletal muscle, body water, intracellular water, protein, and body cell mass in accelerated rehabilitation group was lower than that in control group (<i>P</i> < 0.05). </sec><sec><strong>Conclusion</strong> The whole-course nutrition management had a positive effect on accelerated recovery in elderly bladder cancer patients. </sec><sec><strong>Methods</strong> 126 elderly patients with bladder cancer were randomly divided into an accelerated rehabilitation group (accelerated recovery surgery group) and a control group (traditional treatment group). The baseline values were registered. After admission, the postoperative hematological indicators (albumin, prealbumin, and hemoglobin), and postoperative related indicators (albumin supplementation, postoperative complication rate, ICU monitoring time, and total hospitalization costs) were recorded to simultaneously measure the differences in body composition between two groups of patients. </sec>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136010253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}