Experimental Aging Research最新文献_第6页

Effects of Interviewer Age on the Reminiscence Bump in Older adults' Autobiographical Memories. 采访者年龄对老年人自传记忆中回忆起伏的影响。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-11-06 DOI: 10.1080/0361073X.2023.2269802

Yoko Sakata

引用次数: 0

Low 25-Hydroxyvitamin D [25(OH)D] Levels as a Predictor of Depressive Symptoms: Evidence from Community-Dwelling Older Adults Population in Mexico City. 低25-羟基维生素D[25（OH）D]水平作为抑郁症状的预测因素：来自墨西哥城社区居住老年人的证据。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-10-13 DOI: 10.1080/0361073X.2023.2269803

Graciela Llanos-Becerra, Eduardo Dávila-Godínez, Norma Torres-Carrillo, Oscar Rosas-Carrasco, Elena Sandoval-Pinto, Raúl Beltrán-Ramírez, Nora Magdalena Torres-Carrillo

{"title":"Low 25-Hydroxyvitamin D [25(OH)D] Levels as a Predictor of Depressive Symptoms: Evidence from Community-Dwelling Older Adults Population in Mexico City.","authors":"Graciela Llanos-Becerra, Eduardo Dávila-Godínez, Norma Torres-Carrillo, Oscar Rosas-Carrasco, Elena Sandoval-Pinto, Raúl Beltrán-Ramírez, Nora Magdalena Torres-Carrillo","doi":"10.1080/0361073X.2023.2269803","DOIUrl":"10.1080/0361073X.2023.2269803","url":null,"abstract":"Objective: The purpose of this study was to assess the association between serum 25-hydroxyvitamin D [25(OH)D] levels and depressive symptoms in Mexican older adults 70 years and older.Methods: A total of 326 adults aged 70 or older from Coyoacán Cohort Study were included in this study. The depressive symptoms were assessing by Center for Epidemiologic Studies Depression Scale (CES-D) and serum 25-hydroxyvitamin D [25(OH)D] levels were measured by commercially available enzyme-linked immunosorbent assay (ELISA).Results: Overall, the prevalence of depressive symptoms was 36.5%. The mean age was 79 years, and 53.4% were women. The total serum 25-hydroxyvitamin D [25(OH)D] levels were lower in older adults with depressive symptoms when compared with older adults without depressive symptoms (p = .006). Logistic regression models showed a significant association between low serum 25(OH)D levels and depressive symptoms even after adjusting for potential confounders (OR = 2.453; 95% CI:1.218-4.939; p = .012). In addition, linear regression model to predict the effect of 25-hydroxyvitamin D [25(OH)D] levels on the CES-D score as a continuous variable, was statistically significant [F(1,324) = 8.54, p = .004], and the R-squared value was .026, indicating that this regression model explains 2.6% of the change in the CES-D score.Conclusion: These results suggest that older Mexican adults with lower serum 25-hydroxyvitamin D [25(OH)D] levels are at higher risk of presenting depressive symptoms.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"742-752"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41196038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Bioceramic Material and Colored Light Irradiation on Learning and Memory in Aging Rats. 生物陶瓷材料和有色光照射对衰老大鼠学习记忆的影响。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-11-16 DOI: 10.1080/0361073X.2023.2278983

Ting-Kai Leung, Yu-Chen Chen, Ming-Wei Chao, Chia-Yi Tseng

{"title":"Effects of Bioceramic Material and Colored Light Irradiation on Learning and Memory in Aging Rats.","authors":"Ting-Kai Leung, Yu-Chen Chen, Ming-Wei Chao, Chia-Yi Tseng","doi":"10.1080/0361073X.2023.2278983","DOIUrl":"10.1080/0361073X.2023.2278983","url":null,"abstract":"Aging is characterized by molecular damage from free radicals, leading to neural dysfunction and memory impairment. This study investigated using bioceramic material and colored light to mitigate neurodegenerative symptoms in aging rats. We assessed the effects of different color light spectrums on D-galactose-induced aging rats using the Morris water maze, novel object recognition, and open field tests. Findings revealed that bioceramic material with various light wavelengths improved activity, recognition, and memory in aging rats. Significant enhancements were observed in the open field and novel object recognition tests, with a trend toward improvement in the Morris water maze. These effects are attributed to the antioxidant properties and microcirculation enhancement associated with bioceramic materials. Color stimulation may impact enzymes, human physiology, psychological activity, and the autonomic nervous system. This study highlights the significance of exploring novel interventions for neurodegenerative symptoms and memory deficits in aging rats. Results indicate that bioceramic material with different colored light spectrums positively influences cognitive function. These findings contribute to our understanding of the therapeutic potential of bioceramic materials and emphasize the need for further research in this area.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"785-799"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136397092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Emotion Reactivity to Predict Facial Emotion Recognition Changes with Aging. 情绪反应预测面部情绪识别随年龄增长而变化的作用

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-09-03 DOI: 10.1080/0361073X.2023.2254658

Noah Hamlin, Katrina Myers, Brittany K Taylor, Gaelle E Doucet

{"title":"Role of Emotion Reactivity to Predict Facial Emotion Recognition Changes with Aging.","authors":"Noah Hamlin, Katrina Myers, Brittany K Taylor, Gaelle E Doucet","doi":"10.1080/0361073X.2023.2254658","DOIUrl":"10.1080/0361073X.2023.2254658","url":null,"abstract":"Emotional intelligence includes an assortment of factors related to emotion function. Such factors involve emotion recognition (in this case via facial expression), emotion trait, reactivity, and regulation. We aimed to investigate how the subjective appraisals of emotional intelligence (i.e. trait, reactivity, and regulation) are associated with objective emotion recognition accuracy, and how these associations differ between young and older adults. Data were extracted from the CamCAN dataset (189 adults: 57 young/118 older) from assessments measuring these emotion constructs. Using linear regression models, we found that greater negative reactivity was associated with better emotion recognition accuracy among older adults, though the pattern was opposite for young adults with the greatest difference in disgust and surprise recognition. Positive reactivity and depression level predicted surprise recognition, with the associations significantly differing between the age groups. The present findings suggest the level to which older and young adults react to emotional stimuli differentially predicts their ability to correctly identify facial emotion expressions. Older adults with higher negative reactivity may be able to integrate their negative emotions effectively in order to recognize other's negative emotions more accurately. Alternatively, young adults may experience interference from negative reactivity, lowering their ability to recognize other's negative emotions.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"550-567"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10908871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10143422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aging in 10 Minutes: Do Age Simulation Suits Mimic Physical Decline in Old Age? Comparing Experimental Data with Established Reference Data. 十分钟衰老：年龄模拟服是否能模拟老年人的体力衰退？将实验数据与既定参考数据进行比较。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-09-13 DOI: 10.1080/0361073X.2023.2256630

Thomas H Gerhardy, Anna Schlomann, Hans-Werner Wahl, Katja Mombaur, Lizeth H Sloot, Laura I Schmidt

{"title":"Aging in 10 Minutes: Do Age Simulation Suits Mimic Physical Decline in Old Age? Comparing Experimental Data with Established Reference Data.","authors":"Thomas H Gerhardy, Anna Schlomann, Hans-Werner Wahl, Katja Mombaur, Lizeth H Sloot, Laura I Schmidt","doi":"10.1080/0361073X.2023.2256630","DOIUrl":"10.1080/0361073X.2023.2256630","url":null,"abstract":"Introduction: Age simulation suits are increasingly used in health care education. However, empirical evidence that quantifies the simulated performance losses in established geriatric tests and compares those declines with reference data of older adults is scarce.Methods: In a standardized lab setting, we compared performance of N = 61 participants (46 middle-aged, 15 young adults) with and without age simulation suit, for example in the Timed Up and Go Test (+dual task), Short Physical Performance Battery, grip strength, and 30-Second-Chair- Standing Test. Additionally, we compared the results with suit to established reference values of older adults in different age groups.Results: Reduced performance was observed in both groups when wearing the suit, yet to different degrees dependent on the assessment and user age. For one, larger declines were observed in more challenging and complex tasks across age groups. In addition, comparisons with reference values revealed age-differential \"instant aging\" effects.Discussion: A simulated \"fourth age,\" where frailty and impairments are accumulating, was not reached in the majority of assessments, especially not among younger participants. In conclusion, existing age simulation suits may have some educational and empathy potential, but so far, they fail in simulating the age period with most serious functional loss.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"692-704"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10227402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validity and Reliability of Work Ability Index in Turkish Context: Inter-Level, Direct, and Indirect Relations with Job Satisfaction and Task Performance. 土耳其背景下工作能力指数的有效性和可靠性：与工作满意度和任务绩效的水平间、直接和间接关系。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-08-23 DOI: 10.1080/0361073X.2023.2250226

Alptekin Develi, Mustafa Fedai Çavuş

{"title":"Validity and Reliability of Work Ability Index in Turkish Context: Inter-Level, Direct, and Indirect Relations with Job Satisfaction and Task Performance.","authors":"Alptekin Develi, Mustafa Fedai Çavuş","doi":"10.1080/0361073X.2023.2250226","DOIUrl":"10.1080/0361073X.2023.2250226","url":null,"abstract":"Descriptive research on work ability is well advanced. However, literature is still far from explaining its consequences. Besides, Turkish literature has been quite limited in terms of considering the work ability concept. In the research, the work ability index, and task performance scale were adapted to Turkish. The research was patterned with quantitative method. According to findings, the improvement of work ability levels and increase in job satisfaction and task performance are related in the same direction. Moreover, work ability positively contributes to directly predicting job satisfaction and task performance. Furthermore, work ability positively contributes to indirectly predicting task performance through job satisfaction. This mediation effect, determined for the first time, is an important research finding regarding its contribution to literature. Apart from these, there are significant differences in work ability among age groups, and certain age group categories have a moderating effect on the relationship between work ability and task performance. This study demonstrated that work ability index is a valid and reliable tool for the Turkish sample. Besides, the study provides holistic findings thanks to work ability levels and direct and indirect effect analysis. The theoretical and practical implications were discussed, and directions were made to further research.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"577-596"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10051401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Association of Social Support, Depression, and Loneliness with Health-Related Quality of Life in Over 50 Years Adults: Ardakan Cohort Study on Ageing (ACSA). 50岁以上成年人的社会支持、抑郁和孤独与健康相关的高质量生活的关系：Ardakan老龄化队列研究（ACSA）。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-10-25 DOI: 10.1080/0361073X.2023.2273164

Ahmad Delbari, Isa Akbarzadeh, Mohammad Saatchi, Fatemeh-Sadat Tabatabaei, Mohammad Bidkhori, Yadollah Abolfathi Momtaz, Reza Mohseni-Bandpey, Elham Hooshmand

{"title":"The Association of Social Support, Depression, and Loneliness with Health-Related Quality of Life in Over 50 Years Adults: Ardakan Cohort Study on Ageing (ACSA).","authors":"Ahmad Delbari, Isa Akbarzadeh, Mohammad Saatchi, Fatemeh-Sadat Tabatabaei, Mohammad Bidkhori, Yadollah Abolfathi Momtaz, Reza Mohseni-Bandpey, Elham Hooshmand","doi":"10.1080/0361073X.2023.2273164","DOIUrl":"10.1080/0361073X.2023.2273164","url":null,"abstract":"Background and aim: Social factors play a crucial role in the quality of life of + 50 adults. This study aimed to investigate the association between social support, depression, and loneliness and the health-related quality of life in + 50 adults of Ardakan.Methods: This was a cross-sectional study from the first phase of Ardakan Cohort Study on Aging (ACSA) in 2019. Health-Related Quality of Life (HRQoL, SF-16), Duke Social Support Index (DSSI), and Center for Epidemiologic Studies Depression Scale (CES-D10) were used to assess the variables of interest. Multivariable linear regression was used to model the associated factors with the score of the SF-16 tool in two dimensions; physical (PCS) and mental (MCS).Findings: A total of 5197 over 50 years individuals included in this study; The mean age was 62.2 ± 7.3 years old, and 52% were male. The mean score for PCS and MCS subscales was 45.6 (95% CI 45.4 to 45.9) and 49.3 (95% CI 49.0 to 49.5), respectively. Adjusted for other variables, having less feeling level of loneliness, and not having depressive symptoms were related to better PCS and MCS scores.Conclusion: The HRQoL for the mental aspect of HRQoL was better than the physical in elder populations. Also, much more focus should be paid to older adults who experience inadequate social support, higher levels of loneliness, and depressive symptoms.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"753-766"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50161174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-11-09 DOI: 10.1080/0361073X.2023.2278985

Kazuyuki Sato, Kazunobu Fukuhara, Takahiro Higuchi

{"title":"Age-Related Changes in the Utilization of Visual Information for Collision Prediction: A Study Using an Affordance-Based Model.","authors":"Kazuyuki Sato, Kazunobu Fukuhara, Takahiro Higuchi","doi":"10.1080/0361073X.2023.2278985","DOIUrl":"10.1080/0361073X.2023.2278985","url":null,"abstract":"The ability to predict collisions with moving objects deteriorates with aging. We followed the affordance-based model to identify optical variables that older adults had difficulty using for collision prediction. We reproduced a modified version of the interception task used in Steinmetz (Steinmetz, Layton, Powell, & Fajen, 2020, \"Affordance-based versus current - future accounts of choosing whether to pursue or abandon the chase of a moving target,\" Journal of Vision, 20(3), 8) in a virtual reality (VR) environment and newly introduced perturbation for each of three optical variables (vertical and horizontal expansions of a moving object and the bearing angle produced between participants and a moving object). We expected that perturbation would negatively affect the performance only for those who rely on the optical variable to perform the interception task effectively. We tested 18 older and 15 younger adults and showed that older participants were not negatively affected by the perturbation for the vertical and horizontal expansion of a moving object, while they showed decreased performance when the perturbation was introduced with a bearing angle. These findings suggest that predicting collisions with moving objects deteriorates with aging because the perception of object expansion is impaired with aging.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"800-816"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71520984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Diffusion Model Account of Cognitive Variability in Healthy Aging and Mild Cognitive Impairment. 健康老龄化和轻度认知障碍中认知变异性的扩散模型解释。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-09-29 DOI: 10.1080/0361073X.2024.2409588

Andrew J Aschenbrenner, Joshua J Jackson

引用次数: 0

AMPA Receptors Endocytosis Inhibition Attenuates Cognition Deficit Via c-Fos/BDNF Signaling in Amyloid β Neurotoxicity. 抑制AMPA受体的内吞作用可通过淀粉样β神经毒性中的c-Fos/BDNF信号转导减轻认知缺陷

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-07-30 DOI: 10.1080/0361073X.2024.2377440

Kimia Eyvani, Negin Letafatkar, Parvin Babaei

{"title":"AMPA Receptors Endocytosis Inhibition Attenuates Cognition Deficit Via c-Fos/BDNF Signaling in Amyloid β Neurotoxicity.","authors":"Kimia Eyvani, Negin Letafatkar, Parvin Babaei","doi":"10.1080/0361073X.2024.2377440","DOIUrl":"https://doi.org/10.1080/0361073X.2024.2377440","url":null,"abstract":"Glutamatergic imbalance, particularly downregulation of α-amino-3-hydroxy-5-methyl-4- isoxazole propionic acid receptor (AMPARs) endocytosis, has been addressed as a possible reason for cognitive dysfunctions in Alzheimer's disease (AD). We hypothesized that inhibition of AMPAR endocytosis may ameliorate memory impairment in AD model of rats. To approach this, twenty-four adults male Wistar rats were divided into three groups: saline + saline (control group), Aβ + saline, and Aβ + Tat-GluR23Y (AMPA endocytosis inhibitor). Animals received an intracerebroventricular (i.c.v) injection of Aβ (1-42) to induce neuro-toxicity, followed by chronic administration of GluR23Y, and further behavioral assessments by MWM. Afterward, the hippocampal level of Brain Derived Neurotrophic Factor (BDNF) and c-Fos was measured via Western blotting. The results of our study revealed that chronic administration of GluR23Y improved both working and reference memories evidenced by shorter latency time and longer total time spent in the target zone in MWM. Additionally, this improvement was paralleled by an increase in BDNF, but a decrease in c-Fos. In conclusion, GluR23Y improves spatial memory impairment at least partly via elevating neuroprotective factor of BDNF and reducing apoptotic protein of c-Fos.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-13"},"PeriodicalIF":1.4,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0