Experimental Aging Research最新文献_第5页

Absent Relations of Religious Coping to Telomere Length in African American and White Women and Men. 非裔美国人和白人女性和男性的宗教应对与端粒长度没有关系。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-07-01 Epub Date: 2023-05-31 DOI: 10.1080/0361073X.2023.2219187

Jason J Ashe, Michele K Evans, Alan B Zonderman, Shari R Waldstein

{"title":"Absent Relations of Religious Coping to Telomere Length in African American and White Women and Men.","authors":"Jason J Ashe, Michele K Evans, Alan B Zonderman, Shari R Waldstein","doi":"10.1080/0361073X.2023.2219187","DOIUrl":"10.1080/0361073X.2023.2219187","url":null,"abstract":"Objectives: This study investigated whether race and sex moderated the relations of religious coping to telomere length (TL), a biomarker of cellular aging implicated in race-related health disparities.Methods: Participant data were drawn from the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study, which included 252 socioeconomically diverse African American and White men and women aged (30-64 years old). Cross-sectional multivariable regression analyses examined interactive associations of religious coping, race, and sex to TL, adjusting for other sociodemographic characteristics.Results: Religious coping was unrelated to TL in this sample (p's > .05). There were no notable race or sex differences. Post hoc exploratory analyses similarly found that neither secular social support coping use nor substance use coping was associated with TL.Conclusion: There was no evidence to support that religious coping use provided protective effects to TL in this sample of African American and White women and men. Nevertheless, future studies should use more comprehensive assessments of religious coping and intersectional identities to provide an in-depth examination of religiosity/spirituality as a potential culturally salient protective factor in cellular aging among African Americans in the context of specific chronic stressors such as discrimination.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9553295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Semantic Priming from Uncued Distractors in Alzheimer's Disease. 阿尔茨海默氏症患者从未预见到的分词中获得语义引物

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-07-01 Epub Date: 2023-04-23 DOI: 10.1080/0361073X.2023.2195294

Julie A Higgins, William Milberg, Regina McGlinchey

引用次数: 0

Effects of Ocimum basilicum L. Extract on Hippocampal Oxidative Stress, Inflammation, and BDNF Expression in Amnesic Aged Rats. 欧鼠李提取物对失忆老年大鼠海马氧化应激、炎症和BDNF表达的影响

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-07-01 Epub Date: 2023-05-08 DOI: 10.1080/0361073X.2023.2210240

Farimah Beheshti, Arefeh Vakilian, Mohsen Navari, Mostafa Zare Moghaddam, Hossein Dinpanah, S Mohammad Ahmadi-Soleimani

{"title":"Effects of Ocimum basilicum L. Extract on Hippocampal Oxidative Stress, Inflammation, and BDNF Expression in Amnesic Aged Rats.","authors":"Farimah Beheshti, Arefeh Vakilian, Mohsen Navari, Mostafa Zare Moghaddam, Hossein Dinpanah, S Mohammad Ahmadi-Soleimani","doi":"10.1080/0361073X.2023.2210240","DOIUrl":"10.1080/0361073X.2023.2210240","url":null,"abstract":"The present study was conducted to investigate the effects of Ocimum basilicum L. (OB) extract on learning and memory impairment in aged rats. Male rats were divided into the following experimental groups: Group 1 (control): including 2 months old rats, Group 2 (aged) including 2 years old rats, Groups 3-5 (aged-OB): including 2 years old rats received 50, 100, and 150 mg/kg OB for 8 weeks by oral gavage. Aging increased the delay to find the platform but, however, decreased the time spent in the target quadrant when tested by Morris water maze (MWM). Aging also reduced the latency to enter the dark chamber in the passive avoidance (PA) test compared to the control group. Moreover, interleukin-6 (IL-6) and malondialdehyde (MDA) levels were raised in the hippocampus and cortex of aged rats. In contrast, thiol levels and enzymatic activity of superoxide dismutase (SOD) and catalase (CAT) significantly reduced. In addition, aging significantly reduced BDNF expression. Finally, OB administration reversed the mentioned effects. The current research showed that OB administration improves learning/memory impairment induced by aging. It also found that this plant extract protects the brain tissues from oxidative damage and neuroinflammation.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9784655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-07-01 Epub Date: 2023-07-06 DOI: 10.1080/0361073X.2023.2233366

Dillon H Murphy, Alan D Castel, Barbara J Knowlton

{"title":"Age-Related Differences in Framing Selective Memory in Terms of Gains and Losses.","authors":"Dillon H Murphy, Alan D Castel, Barbara J Knowlton","doi":"10.1080/0361073X.2023.2233366","DOIUrl":"10.1080/0361073X.2023.2233366","url":null,"abstract":"We examined whether framing younger and older adults learning goals in terms of maximizing gains or minimizing losses impacts their ability to selectively remember high-value information. Specifically, we presented younger and older adults with lists of words paired with point values and participants were either told that they would receive the value associated with each word if they recalled it on a test or that they would lose the points associated with each word if they failed to recall it on the test. We also asked participants to predict the likelihood of recalling each word to determine if younger and older adults were metacognitively aware of any potential framing effects. Results revealed that older adults expected to be more selective when their goals were framed in terms of losses, but younger adults expected to be more selective when their goals were framed in terms of gains. However, this was not the case as both younger and older adults were more selective for high-value information when their goals were framed in terms of maximizing gains compared with minimizing losses. Thus, the framing of learning goals can impact metacognitive decisions and subsequent memory in both younger and older adults.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10770296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9758885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring Effects of Age on Conflict Processing in the Light of Practice in a Large-Scale Dataset. 从大规模数据集的实践角度探讨年龄对冲突处理的影响。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-07-01 Epub Date: 2023-05-31 DOI: 10.1080/0361073X.2023.2214051

Fabiola Reiber, Rolf Ulrich

{"title":"Exploring Effects of Age on Conflict Processing in the Light of Practice in a Large-Scale Dataset.","authors":"Fabiola Reiber, Rolf Ulrich","doi":"10.1080/0361073X.2023.2214051","DOIUrl":"10.1080/0361073X.2023.2214051","url":null,"abstract":"Introduction: The possible decline of cognitive functions with age has been in the focus of cognitive research in the last decades. The present study investigated effects of aging on conflict processing in a big dataset of a Stroop-inspired online training task.Methods: We focused on the temporal dynamics of conflict processing in the light of task practice by means of inspecting delta plots and Lorenz-interference curves to gain insights on a process level.Results: The results indicate a relatively constant increase of cognitive conflict over the course of adulthood and a decrease with practice. Furthermore, the latency of the automatic processing of conflicting information relative to the controlled processing of task-relevant information decreases relatively constantly with age. This effect is moderated by practice, that is, the relative latency of the automatic processing decreases less with age at high practice levels.Conclusion: As such, practice seems to be able to partially counteract age-related differences in conflict processing, on a process level.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9606859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Increase in Linguistic Complexity in Older Adults During COVID-19. COVID-19 期间老年人语言复杂性的增加。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-05-01 Epub Date: 2023-03-09 DOI: 10.1080/0361073X.2022.2163831

Megan Karabin, Aki-Juhani Kyröläinen, Victor Kuperman

引用次数: 0

The body of evidence of late-life depression: the complex relationship between depressive symptoms, movement, dyspnea and cognition. 晚年抑郁症的证据：抑郁症状、运动、呼吸困难和认知之间的复杂关系。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-05-01 Epub Date: 2023-04-10 DOI: 10.1080/0361073X.2023.2196504

Martino Belvederi Murri, Federico Triolo, Alice Coni, Erika Nerozzi, Pasqualino Maietta Latessa, Silvia Fantozzi, Nicola Padula, Andrea Escelsior, Barbara Assirelli, Giuliano Ermini, Luigi Bagnoli, Donato Zocchi, Aderville Cabassi, Stefano Tedeschi, Giulio Toni, Rabih Chattat, Ferdinando Tripi, Francesca Neviani, Marco Bertolotti, Alessandro Cremonini, Klea D Bertakis, Mario Amore, Lorenzo Chiari, Stamatula Zanetidou

{"title":"The body of evidence of late-life depression: the complex relationship between depressive symptoms, movement, dyspnea and cognition.","authors":"Martino Belvederi Murri, Federico Triolo, Alice Coni, Erika Nerozzi, Pasqualino Maietta Latessa, Silvia Fantozzi, Nicola Padula, Andrea Escelsior, Barbara Assirelli, Giuliano Ermini, Luigi Bagnoli, Donato Zocchi, Aderville Cabassi, Stefano Tedeschi, Giulio Toni, Rabih Chattat, Ferdinando Tripi, Francesca Neviani, Marco Bertolotti, Alessandro Cremonini, Klea D Bertakis, Mario Amore, Lorenzo Chiari, Stamatula Zanetidou","doi":"10.1080/0361073X.2023.2196504","DOIUrl":"10.1080/0361073X.2023.2196504","url":null,"abstract":"Background: Physical symptoms play an important role in late-life depression and may contribute to residual symptomatology after antidepressant treatment. In this exploratory study, we examined the role of specific bodily dimensions including movement, respiratory functions, fear of falling, cognition, and physical weakness in older people with depression.Methods: Clinically stable older patients with major depression within a Psychiatric Consultation-Liaison program for Primary Care underwent comprehensive assessment of depressive symptoms, instrumental movement analysis, dyspnea, weakness, activity limitations, cognitive function, and fear of falling. Network analysis was performed to explore the unique adjusted associations between clinical dimensions.Results: Sadness was associated with worse turning and walking ability and movement transitions from walking to sitting, as well as with worse general cognitive abilities. Sadness was also connected with dyspnea, while neurovegetative depressive burden was connected with activity limitations.Discussion: Limitations of motor and cognitive function, dyspnea, and weakness may contribute to the persistence of residual symptoms of late-life depression.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9318565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Social frailty among older adults in India: Findings from the Longitudinal Ageing Study in India (LASI) - Wave 1. 印度老年人的社会脆弱性：印度老龄化纵向研究（LASI）--第 1 波的结果。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-05-01 Epub Date: 2023-03-28 DOI: 10.1080/0361073X.2023.2195291

Cv Irshad, Dipti Govil, Harihar Sahoo

{"title":"Social frailty among older adults in India: Findings from the Longitudinal Ageing Study in India (LASI) - Wave 1.","authors":"Cv Irshad, Dipti Govil, Harihar Sahoo","doi":"10.1080/0361073X.2023.2195291","DOIUrl":"10.1080/0361073X.2023.2195291","url":null,"abstract":"Background: From an individual's perspective, social frailty may act as a key determinant of social capital, which is essential for meeting social needs and improvement of overall wellbeing. The present study aimed to understand the social frailty and its determining factors among Indian older adults.Methods: Data from the Longitudinal Ageing Study in India (LASI)-wave 1 was used. For the assessment of social frailty the study proposed a multidimensional Social Frailty Index (SFI) score ranging between 0 and 100 using 17 indicators. Bivariate analysis and quantile regression models were applied.Results: The study results indicated that on average female older adults (mean SFI = 63.7) are relatively more socially frail than male older adults (mean SFI = 59.0). Further, the quantile regression analysis revealed that at the 10th, 25th, 50th, and 75th percentiles, female older adults were significantly more likely to be socially frail than male older adults (β = 3.80, p < .01; β = 2.82, p < .01; β = 1.72, p < .01; and β = 2.62, p < .01, respectively). Educational attainment and better economic condition showed a protective effect against social frailty.Conclusions: Investment to improve geriatric health status and socioeconomic conditions shall be a key focus to reduce social frailty prevalence among the older adults. A specific consideration is needed for addressing social frailty among female older adults.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9199386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-05-01 Epub Date: 2023-03-28 DOI: 10.1080/0361073X.2023.2195293

Daiane Aparecida Damasceno, Gabriel Ferreira Aleixo, Jean Barbosa Luciano, Claudio Mardey Nogueira, Juliana Martins Pinto

{"title":"Factors Related to Recurrent Falls Among Older Adults Attending Primary Health Care: A Biopsychosocial Perspective.","authors":"Daiane Aparecida Damasceno, Gabriel Ferreira Aleixo, Jean Barbosa Luciano, Claudio Mardey Nogueira, Juliana Martins Pinto","doi":"10.1080/0361073X.2023.2195293","DOIUrl":"10.1080/0361073X.2023.2195293","url":null,"abstract":"The objective of this study was to investigate factors related to recurrent falls among older adults attending primary health care, considering the biopsychosocial perspective. A representative sample of 201 older adults were interviewed in three Primary Health Care units randomly selected in a city in southeastern Brazil. Outcome included self-report of two or more falls in the past 12 months. Exposures included personal and environmental aspects, according to domains of International Classification of Functioning of the World Health Organization (ICF-WHO). Recurrent falls were reported by 24.4% of the participants. Associations with depressive symptoms (p = .003), having osteoporosis (p = .031), chronic musculoskeletal pain (p = .020), frailty (p = .013), sleep satisfaction (p < .001), and functional status (p < .001) were found. In logistic regression models, cognitive status, musculoskeletal pain, and functional status were predictors of recurrent falls; however, only sleep satisfaction remained significant in the final model. Strategies aimed at preventing recurrent falls in primary health care should consider assessments and interventions targeting sleep aspects among older adults.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9199393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Depressive Symptoms are Associated with Decline Over Time in Verbal Fluency Performance in Female but Not Male Community-Dwelling Older Adults. 抑郁症状与居住在社区的老年女性（而非男性）语言流利性随时间的下降有关。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-05-01 Epub Date: 2023-03-29 DOI: 10.1080/0361073X.2023.2195295

Jessica S Wasserman, Roee Holtzer

{"title":"Depressive Symptoms are Associated with Decline Over Time in Verbal Fluency Performance in Female but Not Male Community-Dwelling Older Adults.","authors":"Jessica S Wasserman, Roee Holtzer","doi":"10.1080/0361073X.2023.2195295","DOIUrl":"10.1080/0361073X.2023.2195295","url":null,"abstract":"Objective: The current study was designed to examine associations between depressive symptoms and longitudinal declines in category and letter fluency performance in a gender-stratified sample of older adults.Method: Participants were community-residing older adults (females: n = 289; males: n = 233) followed annually (2011-2018) as part of a cohort study conducted at Albert Einstein College of Medicine in New York. Depressive symptoms were assessed using the Geriatric Depression Scale (GDS). Standard forms assessed category and letter fluency performance. Participants were dementia-free during study enrollment.Results: The presence of baseline depressive symptoms suggestive of subclinical depression was associated with a worse longitudinal decline in category fluency performance in female but not male participants. These associations remained significant when excluding participants with prevalent and incident mild cognitive impairment and incident dementia. Irrespective of gender, letter fluency performance did not decline over time and was not influenced by the presence of depressive symptoms.Discussion: The present study's results can aid in identification of older adults who may be at greater risk for cognitive decline, and add to the limited literature examining the influence of gender on longitudinal associations between depressive symptoms and verbal fluency performance.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9203848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0