Experimental Aging Research最新文献_第5页

Cognitive Performance following Single- or Multi-Session Exercise Intervention in Middle Age: A Systematic Review. 中年人单次或多次运动干预后的认知表现：系统回顾

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-01-01 Epub Date: 2022-11-17 DOI: 10.1080/0361073X.2022.2137360

Fayeza S Ahmed, Taylor M McMillan, Benjamin A Guenther, Peter Dearborn

{"title":"Cognitive Performance following Single- or Multi-Session Exercise Intervention in Middle Age: A Systematic Review.","authors":"Fayeza S Ahmed, Taylor M McMillan, Benjamin A Guenther, Peter Dearborn","doi":"10.1080/0361073X.2022.2137360","DOIUrl":"10.1080/0361073X.2022.2137360","url":null,"abstract":"Background: Research in modifiable behaviors, like exercise, on risk for dementia is increasing. Although many studies focus on older adults, brain pathology for Alzheimer's Disease can begin in middle age, suggesting an ideal target for intervention.Methods: We conducted a systematic review from exercise intervention studies on cognitive function among healthy, middle-aged participants (45-65). We searched multiple databases (PubMed, PsycINFO, MEDLINE, Cochrane Central Register of Controlled Trials, Google Scholar) for studies using standard, validated, neuropsychological measures following either single- or multi-session interventions in cognitively-unimpaired, middle-aged adults.Results: We identified 13 eligible studies. There was notable heterogeneity across studies, with varying design, measures, interventions, and results. Results from single-session studies showed improvement in response inhibition, while results for cognitive flexibility were mixed. No significant changes were found on measures of attention, working memory, or processing speed. Results from multi-session studies were more varied. Verbal memory was found to improve while performance on tests of attention and working memory, processing speed, and executive function were mixed.Conclusion: Importantly, for both single-session and multi-session studies, there was no standard set of neuropsychological tests administered, making it more difficult to synthesize the findings into a single narrative. We end with a discussion on future directions and implementation.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40687859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Olfactory Dysfunction Associated with Cognitive Decline in an Elderly Population. 与老年人认知能力下降有关的嗅觉功能障碍

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-01-01 Epub Date: 2022-12-22 DOI: 10.1080/0361073X.2022.2160597

Majed Alotaibi, Melissa Lessard-Beaudoin, Kate Busch, Amal Loudghi, Pierrette Gaudreau, Rona K Graham

{"title":"Olfactory Dysfunction Associated with Cognitive Decline in an Elderly Population.","authors":"Majed Alotaibi, Melissa Lessard-Beaudoin, Kate Busch, Amal Loudghi, Pierrette Gaudreau, Rona K Graham","doi":"10.1080/0361073X.2022.2160597","DOIUrl":"10.1080/0361073X.2022.2160597","url":null,"abstract":"Background: In many neurological disorders, including Alzheimer disease, early olfactory dysfunction is observed.Objective: In order to determine if deficits in olfactory memory are present in the elderly and if olfactory dysfunction correlates with cognitive impairment in the aging population, olfactory testing has been done on seniors from the NuAge cohort accepting to participate in the Olfactory Response Cognition and Aging (ORCA) secondary sub-study. The t-Mini Mental Statement Examination and the Telephone Interview for Cognitive Status tests were done to assess cognition levels.Results: Overall, 94% of the ORCA cohort displayed olfactory dysfunction. Deficits in olfactory memory were also present. A correlation was observed between olfactory function and cognitive test scores. Moreover, in women who smoked, there was an association between olfactory memory and cognitive scores.Conclusion: Our results suggest that olfactory dysfunction may predict impending cognitive decline and highlights the need for olfactory training in seniors to improve olfaction and overall well-being.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10474812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Age Differences in Gaze Following: Older Adults Follow Gaze More than Younger Adults When free-viewing Scenes. 目光追随的年龄差异：在自由观看场景时，老年人比年轻人更关注目光。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-01-01 Epub Date: 2022-12-26 DOI: 10.1080/0361073X.2022.2156760

Eunice G Fernandes, Benjamin W Tatler, Gillian Slessor, Louise H Phillips

引用次数: 0

Cognitive Status is Better in Older Adults under Colchicine Treatment: A Case-Control Study. 接受秋水仙碱治疗的老年人认知状况更好：病例对照研究

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-01-01 Epub Date: 2022-11-14 DOI: 10.1080/0361073X.2022.2145164

Arzu Okyar Baş, Gözde Kübra Yardımcı, Merve Güner Oytun, Serdar Ceylan, Zeynep Kahyaoğlu, Yelda Öztürk, Süheyla Çöteli, Meltem Gülhan Halil, Mustafa Cankurtaran, Levent Kılıç, Burcu Balam Doğu Yavuz

{"title":"Cognitive Status is Better in Older Adults under Colchicine Treatment: A Case-Control Study.","authors":"Arzu Okyar Baş, Gözde Kübra Yardımcı, Merve Güner Oytun, Serdar Ceylan, Zeynep Kahyaoğlu, Yelda Öztürk, Süheyla Çöteli, Meltem Gülhan Halil, Mustafa Cankurtaran, Levent Kılıç, Burcu Balam Doğu Yavuz","doi":"10.1080/0361073X.2022.2145164","DOIUrl":"10.1080/0361073X.2022.2145164","url":null,"abstract":"Purpose: We aimed to investigate the effects of colchicine, an important anti-inflammatory agent, on cognitive functions in a geriatric population diagnosed with gout or osteoarthritis by comparing it to non-colchicine users.Methods: 138 geriatric patients (67 colchicine users and 71 non-users) were enrolled. Within comprehensive geriatric assessment (CGA), cognitive status assessment via Mini-Mental State Examination test (MMSE), Quick Mild Cognitive Impairment Screening test (Qmci), clock drowning test (CDT), and digit span tests were performed.Results: Median age was 68 (65-72), and there were 82 female (59.4%) patients. The scores of CDT, Backward Digit Span Test, MMSE-Total, MMSE-Attention, MMSE-Motor Function, Qmci-Total Score, Qmci-Clock drawing, and Qmci-Logical Memory were significantly higher in the colchicine user group (p < .005), showing better cognitive function. Adjusted model analysis showed that colchicine usage is independently correlated with higher Qmci-Total Score and Qmci-Logical Memory Score (For Qmci total score β = 7.87 95%CI = 5.48-10.27, p = <0.0001, and for Qmci Logical memory score β = 3.52, 95%CI = 2.12-4.91, p = <0.0001).Conclusion: To the best of our knowledge, this is the first study revealing that colchicine usage is associated with better cognitive performance in older adults. Further investigations with a prospective, larger-sampled and randomized design are needed to show the causal relationship between colchicine and cognition.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40701662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metamemory Mediates the Effects of Age on Episodic and Working Memory across the Adult Lifespan. 元记忆调节年龄对整个成年期的外显记忆和工作记忆的影响

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2024-01-01 Epub Date: 2022-12-13 DOI: 10.1080/0361073X.2022.2158004

Selene Cansino, Frine Torres-Trejo, Cinthya Estrada-Manilla, Silvia Ruiz Velasco

{"title":"Metamemory Mediates the Effects of Age on Episodic and Working Memory across the Adult Lifespan.","authors":"Selene Cansino, Frine Torres-Trejo, Cinthya Estrada-Manilla, Silvia Ruiz Velasco","doi":"10.1080/0361073X.2022.2158004","DOIUrl":"10.1080/0361073X.2022.2158004","url":null,"abstract":"Background: Previous studies have examined the direct relationship between metamemory and memory performance in young and older adults, but the results of these studies have been inconsistent. Therefore, we examined whether metamemory mediates the effects of age on memory performance.Methods: We examined episodic memory and working memory through computerized tasks performed by a lifespan sample of 1554 healthy adults. Seven metamemory traits were measured with the Metamemory in Adulthood (MIA) questionnaire. Separate structural equation modeling analyses were conducted to investigate potential metamemory mediators that intervened between age and the accuracy and speed of accessing information from episodic and working memory.Results: The use of internal or external strategies mediated the effects of age on episodic memory and spatial working memory performance. The perception of one's own memory capacity and the experience of anxiety when using memory functions mediated the effects of age on working memory performance in both domains.Conclusions: Metamemory traits have the power to strengthen or weaken the course of episodic and working memory decline throughout adulthood.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10325586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exposure to Memory-Relevant versus Memory-Irrelevant Aging Stereotypes Differentially Affects Memory Self-Perceptions and Memory Test Scores of Young, Middle, and Older Age Adults. 接触与记忆相关和与记忆无关的老龄化刻板印象会对青年、中年和老年成人的记忆自我认知和记忆测试成绩产生不同影响。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-12-21 DOI: 10.1080/0361073X.2023.2295202

Tara T Lineweaver, Annie C Wetli, Coty Nicoson, Ashley J Tucker, Christopher Hertzog

{"title":"Exposure to Memory-Relevant versus Memory-Irrelevant Aging Stereotypes Differentially Affects Memory Self-Perceptions and Memory Test Scores of Young, Middle, and Older Age Adults.","authors":"Tara T Lineweaver, Annie C Wetli, Coty Nicoson, Ashley J Tucker, Christopher Hertzog","doi":"10.1080/0361073X.2023.2295202","DOIUrl":"https://doi.org/10.1080/0361073X.2023.2295202","url":null,"abstract":"This study examined the combined influence of assimilation and contrast effects on the memory self-efficacy and objective memory of young (ages 18-25, n = 114), middle-age (ages 26-59, n = 48), and older (ages 60-98, n = 59) adults. We reminded participants that they matched positive, not negative, memory-relevant or memory-irrelevant stereotypes of aging either before (experimental conditions) or after (control condition) they completed a memory self-efficacy questionnaire and took a memory test. Participants exposed to memory-relevant aging stereotypes prior to other measures reported higher memory self-efficacy than those exposed to memory-irrelevant stereotypes; this effect did not depend on age group. In contrast, the effect of stereotype exposure on memory performance differed with age. Young and older, but not middle-aged, adults showed differences in their memory scores depending on whether they were exposed to memory-relevant, memory-irrelevant or no aging stereotypes. In general, exposure to stereotypes (particularly those relevant to memory) had a negative influence on memory that contrasted with its positive effect on memory self-efficacy. Together, these results indicate that exposure to aging stereotypes can have opposing effects on the memory self-efficacy and objective test performance of adults of various ages and that the relevance of the stereotypes to the cognitive domain being assessed matters.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138829120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congruent Prosody Reduces Cognitive Effort in Memory for Spoken Sentences: A Pupillometric Study with Young and Older Adults 一致的前置词可减少口语句子记忆的认知努力：针对年轻人和老年人的瞳孔测量研究

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-12-07 DOI: 10.1080/0361073x.2023.2286872

Ryan M. O’Leary, Nicole M. Amichetti, Zoe Brown, Alexander J. Kinney, Arthur Wingfield

引用次数: 0

COPD, Dietary Fiber Intake, and Cognitive Performance in Older Adults: A Cross-Sectional Study from NHANES 2011-2014. 慢性阻塞性肺病、膳食纤维摄入量和老年人认知能力:来自NHANES 2011-2014的横断面研究

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-11-27 DOI: 10.1080/0361073X.2023.2286874

Songlan Liang, Xu Han, Shuang Diao, Hui Li

{"title":"COPD, Dietary Fiber Intake, and Cognitive Performance in Older Adults: A Cross-Sectional Study from NHANES 2011-2014.","authors":"Songlan Liang, Xu Han, Shuang Diao, Hui Li","doi":"10.1080/0361073X.2023.2286874","DOIUrl":"https://doi.org/10.1080/0361073X.2023.2286874","url":null,"abstract":"Introduction: This study aimed to evaluate the modifying role of dietary fiber intake in the relationship between COPD and cognitive performance.Methods: Data of adults aged ≥60 years were extracted from the National Health and Nutrition Examination Survey (NHANES) 2011-2014. Participants with information on cognitive function measures were included. Dietary fiber intake, identified using participants' 24-h recall surveys, was grouped into high (>25 g/day) and low (≤25 g/day) levels. COPD was identified through self-reported physician diagnoses. Associations between dietary fiber intake, cognitive function and COPD were evaluated using the regression analysis.Results: Data of 2,189 participants were analyzed. Multivariate analysis revealed that COPD was significantly associated with lowered CERAD (adjusted beta [aBeta]: -0.17, 95% confidence interval [CI]: -0.33 to -0.002, p = .047) and DSST (aBeta: -2.23, 95% CI: -4.25 to -0.2, p = .032) scores in older adults. The analysis on the association between COPD and cognitive function stratified by dietary fiber intake revealed that COPD remained significantly associated with lowered CREAD among individuals with a high fiber intake (aBeta: -0.54, 95% CI: -1.00 to -0.08, p = .024).Conclusions: In US older adults, COPD is associated with reduced cognitive function. However, the findings do not support that high dietary fiber intake may modify the association between COPD and cognitive impairment.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138444418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effects of Vitamin D on Movement and Cognitive Function in Senile Mice After Sevoflurane Anaesthesia. 维生素D对七氟醚麻醉后老年小鼠运动和认知功能的影响。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-11-22 DOI: 10.1080/0361073X.2023.2282350

Jialei Zhang, Xiaoling Zhang, Jun Zhao, Jie Wu

{"title":"The Effects of Vitamin D on Movement and Cognitive Function in Senile Mice After Sevoflurane Anaesthesia.","authors":"Jialei Zhang, Xiaoling Zhang, Jun Zhao, Jie Wu","doi":"10.1080/0361073X.2023.2282350","DOIUrl":"https://doi.org/10.1080/0361073X.2023.2282350","url":null,"abstract":"Background: Vitamin D (VD) is a neuroactive steroid involved in many brain functions, such as neurotrophic, neuroimmune control and neurotransmission, which affects the growth and function of the brain. The purpose of this study is to explore the effect of VD on motor and cognitive function of aged mice after sevoflurane anesthesia.Method: We established sevoflurane anesthesia model and VD(-) and VD(+) mice model. The VD concentration of mice in each group was determined by enzyme-linked immunosorbent assay (ELISA). An open-field test was used to evaluate the mice's capacity for movement and exploration. A Y-maze test was used to gauge the mice's short-term memory. The primary purpose of the water-maze experiment was to examine mice's long-term spatial memory.Results: The ELISA results showed that the model was successfully constructed. In the open-field test, VD increased the exercise distance of mice (P < .05). In the Y-maze experiment, VD improved short-term memory impairment in mice (P < .05). In the water-maze test, VD increased the activity time and platform crossing number of mice in the target quadrant. (P < .05).Conclusion: Sevoflurane anesthesia caused cognitive dysfunction in aged mice, including reduced learning ability, memory loss, lower motor and exploratory abilities and depression, and VD deficiency aggravated these impairments. By supplementing with VD, learning ability and long-term memory were enhanced, motor and exploratory abilities were improved, and depression levels were reduced. Anxiety was also improved.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138290692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship Between Quality of Life and Depressive Symptoms Among Jordanian Community-Dwelling Older Adults. 约旦社区老年人生活质量与抑郁症状的关系

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-11-22 DOI: 10.1080/0361073X.2023.2286873

Malakeh Z Malak, Anas H Khalifeh

{"title":"The Relationship Between Quality of Life and Depressive Symptoms Among Jordanian Community-Dwelling Older Adults.","authors":"Malakeh Z Malak, Anas H Khalifeh","doi":"10.1080/0361073X.2023.2286873","DOIUrl":"https://doi.org/10.1080/0361073X.2023.2286873","url":null,"abstract":"Objective: The current study aimed to examine the relationship between depressive symptoms and quality of life among Jordanian community-dwelling older adults.Methods: A cross-sectional, descriptive correlational design was used. A convenience sample (N = 602) was selected to recruit the participants in the Amman governorate during the period from August to November 2021.Results: Findings demonstrated that the mean (SD) age of older adults was 67.5 (7.0) years and 51.5% of participants were females. Also, 54.1% of the participants experienced moderate to severe depressive symptoms with a total mean (SD) score was 8.57 on a scale of 0 to 15, while the mean (SD) for the quality of life scale was 12.12 (3.85) on a scale of 4 to 20. Significant differences existed in quality of life and depressive symptoms based on marital status (p < .001), educational level (p < .001), working status (p < .01), income (p < .001), and chronic disease (p < .01). Quality of life and its domains were negatively associated with depressive symptoms (B= - 0.596, p < .001). Also, marital status, working, educational level, income, and chronic disease were associated with depressive symptoms.Conclusion: Strategies to improve quality of life should be promoted to minimize depressive symptoms among older adults and consider significant demographic factors.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138290693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0