Experimental and clinical psychopharmacology最新文献

{"title":"A pilot study of impulsivity and subjective alcohol response in the lab and moment.","authors":"Amy L Stamates, Sabrina M Todaro, Anna L Sherman, Melissa Rothstein, Dahianna López","doi":"10.1037/pha0000779","DOIUrl":"10.1037/pha0000779","url":null,"abstract":"<p><p>Impulsivity and individual differences in alcohol sensitivity (e.g., subjective response to alcohol) have been related to alcohol use behaviors, but scant research has examined how these two constructs are related to each other. Consequently, this pilot study aimed (1) to examine associations between impulsivity domains (impulsive action, impulsive choice, and impulsive personality features) and alcohol sensitivity during alcohol administration in the laboratory; (2) to test daily associations between impulsivity domains and sensitivity to reward during ecological momentary assessment (EMA); and (3) to explore consistency between alcohol sensitivity scores in the lab and EMA. Participants (<i>N</i> = 26; 38.5% male, 61.5% female) were students (graduate and undergraduate) who engaged in recent (past-month) alcohol use and heavy drinking in the past 6 months. Participants completed an in-person alcohol administration session followed by 10 days of EMA. For Aim 1, results indicated that individuals with a greater lack of perseverance reported greater cravings and willingness to drive during the alcohol administration session. Negative and positive urgency were positively associated with liking the alcoholic beverage. For Aim 2, within-person associations revealed that greater than usual lack of premeditation was associated with greater craving while drinking, and greater than usual lack of perseverance was related to less willingness to drive. For Aim 3, subjective effects for liking, craving, and stimulation scores were greater during the EMA portion as compared to the laboratory session. Our findings suggested that individual differences in some impulsive personality features played a role in the motivation to consume alcohol in the laboratory and real world. Future research should replicate these pilot findings and expand on contextual factors that may be driving the present study's associations. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":12089,"journal":{"name":"Experimental and clinical psychopharmacology","volume":" ","pages":"361-370"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12313404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of sertraline on depressive symptoms, serum brain-derived neurotrophic factor (BDNF), 5-HT, and inflammatory cytokine expression in pediatric depression patients.","authors":"Zhenbo Wu, Hongyu Chen, Li Li, Yanyan Huang, Qinghua Lan, Hanjun Zhu, Songmei Luo","doi":"10.1037/pha0000768","DOIUrl":"10.1037/pha0000768","url":null,"abstract":"<p><p>This study investigated the therapeutic effects of sertraline in pediatric patients diagnosed with depression, focusing on its impact on serum levels of brain-derived neurotrophic factor (BDNF), serotonin (5-HT), and inflammatory cytokines. A total of 164 pediatric patients were randomly divided into two groups: the sertraline and control groups, with 82 participants in each. Depressive symptoms were evaluated at 2 and 4 weeks using the 17-item Hamilton Depression Rating Scale (HAMD-17) and the Children's Depression Rating Scale-Revised (CDRS-R). Serum concentrations of BDNF, 5-HT, and inflammatory cytokines (interleukin-1β, interleukin-6, and tumor necrosis factor-α) were quantified using ELISA. Results demonstrated no significant differences in baseline characteristics between the groups. After 4 weeks, both groups showed reductions in HAMD-17 and CDRS-R scores and interleukin-1β and tumor necrosis factor-α levels, as well as increases in BDNF and 5-HT levels. Notably, at the 2-week mark, the sertraline group had significantly lower scores in both depression scales and inflammatory cytokines compared to the control group (fluoxetine treatment), indicating an early onset of action. Despite these findings, by 4 weeks, differences in HAMD-17 and CDRS-R scores, BDNF, and 5-HT levels between the two groups were no longer significant, although the sertraline group maintained lower levels of inflammatory cytokines. Additionally, the sertraline group reported higher rates of early improvement and adverse events, though no significant differences in remission or response rates were found between the groups. Overall, sertraline demonstrates effectiveness in alleviating depressive symptoms in children during the initial treatment period, potentially via mechanisms involving BDNF, 5-HT, and inflammation modulation, although it presents a less favorable safety profile compared to fluoxetine. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":12089,"journal":{"name":"Experimental and clinical psychopharmacology","volume":" ","pages":"416-423"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity evidence and clinical utility of the Oviedo Leisure Activities Scale (OLAS-70) for measuring substance-free and substance-related reinforcement.","authors":"Alba González-Roz, Roberto Secades-Villa, Layla Alemán-Moussa","doi":"10.1037/pha0000771","DOIUrl":"10.1037/pha0000771","url":null,"abstract":"<p><p>Substance use disorders (SUDs) can be explained in part by the availability and amount of alternative substance-free reinforcers, which are recognized as the main target in treatment of SUDs. Most questionnaires examining this area assess activities in teens or young adults from the general population and, have not been assessed in the context of treatment of SUDs, and do not address the wide range that is needed in order to plan recreational activities that are incompatible with substance use in clinical contexts, as well as to identify activities that could pose a risk for relapse. This study aimed to develop a new instrument (i.e., the Oviedo Leisure Activities Scale; OLAS-70) to measure substance-free and substance-related reinforcement. It also sought to provide validity evidence based on the relationship with the European Addiction Severity Index, the Patient Health Questionnaire-9, and the Reward Probability Index. The participants in this cross-sectional study were 542 adults (<i>M</i>_age = 38.71, <i>SD</i> = 10.66) undergoing inpatient or outpatient interventions for SUDs. Participants completed the European Addiction Severity Index, the Patient Health Questionnaire-9, the Reward Probability Index, and the OLAS-70 within a month of starting treatment. The OLAS-70 demonstrated validity evidence in relation to addiction severity, depression, and probability of environmental reward. Participants with drug use problems according to the European Addiction Severity Index exhibited higher proportion of substance-related reinforcement ratio due to engaging in activities while under the influence of substances, including sports, hobbies, and artistic activities. The OLAS-70 is valid for measuring both substance-free and substance-related reinforcement and provides clinically useful information for treatment planning, identifying high-risk situations for substance use relapse, and scheduling reinforcing, positive activities during interventions. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":12089,"journal":{"name":"Experimental and clinical psychopharmacology","volume":" ","pages":"330-341"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental perceptions of contingency management for adolescent substance use: Acceptability, willingness to pay, and preferences.","authors":"Precious Mathis, Fodie Koita, Grace Beuley, Stacy R Ryan-Pettes","doi":"10.1037/pha0000778","DOIUrl":"10.1037/pha0000778","url":null,"abstract":"<p><p>Despite robust evidence, there is a low uptake of incentive-based contingency management (CM) for substance use treatment due to provider worries about client perceptions of CM and high implementation costs. Research has attempted to address these concerns to facilitate the dissemination of CM for adult substance use. However, little research has explored these barriers to disseminating CM for adolescents. The present study assessed the degree to which parents (those most likely to be payors of adolescent treatment) held positive and negative views of incentives for substance use treatment, preferred fixed- versus variable-ratio schedules of reinforcement and immediate versus delayed receipt of reinforcers, and were willing to pay for incentive-based treatment. One hundred twenty-three parents of adolescents currently using substances (<i>N</i> = 123) were recruited via Facebook to participate in a survey study. While results show parents endorsed some objections, parents overwhelmingly endorsed positive views about incentives for adolescent substance use treatment and indicated a willingness to pay out-of-pocket costs. Also, parents endorsed incentives with fixed amounts over variable amounts. Finally, parent age was significantly associated with the likelihood of accepting incentives, and perception of incentives was significantly associated with the likelihood of agreeing to engage and willingness to pay for incentive-based treatment. This study showed parents largely accept the idea of incentives for substance use treatment and support exploring a self-pay model to increase the dissemination of CM. Research is needed to examine perceptions of incentives for substance use treatment among adolescents themselves and explore novel ways of integrating voucher- and prize-based procedures. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":12089,"journal":{"name":"Experimental and clinical psychopharmacology","volume":" ","pages":"323-329"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of alcohol on the speed of shifting endogenous and exogenous attention.","authors":"Alexander Thiele, Christopher Heath, Sidharth Sanjeev, Jenny C A Read","doi":"10.1037/pha0000774","DOIUrl":"10.1037/pha0000774","url":null,"abstract":"<p><p>The study aimed to investigate to what extent acute moderate doses of alcohol affect the speed of endogenous versus exogenous attentional shift times. Subjects viewed an array of 10 moving clocks and reported the time a clock indicated when cued. Target clocks were indicated by cues, presented peripherally at the target clock or centrally pointing toward a target clock, including conditions of where the target location was cued in advance, that is, precueing. This allowed assessing shift times when attention was preallocated, when peripheral cues triggered exogenous attention shifts, and when central cues triggered endogenous attention shifts. Each subject participated in two sessions (alcohol/placebo), whereby the order of alcohol/placebo intake was counterbalanced across subjects, and subjects were blinded to conditions. Confirming previous results, we show that precuing resulted in the fastest shift times, followed by exogenous cuing, with endogenous attentional shifts being slowest. Alcohol increased attentional shift times across all three conditions compared to placebo. Thus, the detrimental effects of alcohol on attentional shift times did not depend on the type of attention probed. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":12089,"journal":{"name":"Experimental and clinical psychopharmacology","volume":" ","pages":"342-351"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-time antecedents of cannabis use among young adults: An Ecological Momentary Assessment study.","authors":"Timothy Regan, Janardan Devkota, Julia McQuoid, Kekoa Lopez-Paguyo, Nhung Nguyen, Meredith C Meacham, Pamela M Ling, Johannes Thrul","doi":"10.1037/pha0000775","DOIUrl":"10.1037/pha0000775","url":null,"abstract":"<p><p>Knowledge regarding in-the-moment antecedents of cannabis use is lacking. We examined internal (e.g., mood, cravings) and external (e.g., locations, people) antecedents of cannabis use among young adults regularly using both cannabis and tobacco. Over 30 days, 36 young adults (<i>M</i>_age = 24.2 years, 33% female, 8% nonbinary, 61% sexual minority, 44% Non-Hispanic White) completed multiple daily Ecological Momentary Assessment surveys, totaling 1,632 prompts. Generalized estimating equations estimated population-averaged relationships between the presence of antecedents and cannabis use outcomes (use vs. nonuse). Overall cannabis use was likelier at neutral ranges of affect (a<i>OR</i> = 0.95; 95% CI [0.91, 1.00]) and affective arousal (a<i>OR</i> = 1.52; 95% CI [0.91, 1.00], see Footnote 1), higher cannabis craving (a<i>OR</i> = 1.52; 95% CI [1.31, 1.76]), and substance intoxication (a<i>OR</i> = 1.25; 95% CI [1.01, 1.55]). Overall use was likelier at home (a<i>OR</i> = 1.97; 95% CI [1.16, 3.37]), and less likely in a place where cannabis smoking was forbidden (a<i>OR</i> = 0.46; 95% CI [0.25, 0.85]) or more people were present (a<i>OR</i> = 0.91; 95% CI [0.87, 0.96]). Other antecedents of use were seeing cannabis product packaging (a<i>OR</i> = 1.91; 95% CI [1.07, 3.39]) and experiencing racial/ethnic-based discrimination (a<i>OR</i> = 2.26; 95% CI [1.39, 3.69]). Future digital interventions for cannabis use will benefit from (a) testing real-time interactions between internal and external antecedents and (b) triggering interventions while users are at home alone, after discrimination experiences, and/or when feeling mild, neutral affect. <i>Note: CIs containing 1.00 interpreted as statistically significant are due to having rounded up to the upper limit</i>. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":12089,"journal":{"name":"Experimental and clinical psychopharmacology","volume":" ","pages":"396-406"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12225398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interplay of cultural beliefs, psychological disposition, and social milieu during childhood on development of substance use disorder by early adulthood.","authors":"Levent Kirisci, Maureen Reynolds, Michael Vanyukov, Tanya Fabian, Ralph Tarter","doi":"10.1037/pha0000776","DOIUrl":"10.1037/pha0000776","url":null,"abstract":"<p><p>This study prospectively examined the interplay of culturally ingrained beliefs regarding the benefits of substance use, social milieu featured by disengaged parents and deviant friends, and behavior undercontrol on the development of substance use disorder (SUD) by early adulthood. The sample at baseline consisted of 497 youths between 10 and 12 years of age. Subsequent evaluations were conducted when the participants attained 12-14, 16, and 22 years of age. The research protocol was composed of self-report, informant report, and performance measures. Positive beliefs about substance use effects were evaluated using the Adolescent Alcohol and Drug Expectancy Questionnaire. The social milieu was characterized by the environtype index encompassing parental engagement and normative behavior of friends. Behavior control was quantified using the neurobehavior disinhibition scale. Substance use frequency and intensity of reward experience during consumption were recorded using the Drug Use Screening Inventory and the Substance Use Questionnaire. The outcome variable, lifetime SUD, was diagnosed using the Structured Clinical Interview for Diagnosis. Structural equation modeling evaluated the association among these variables. Beliefs regarding the benefits of consumption mediated the associations of childhood social milieu with substance use frequency and reward intensity during the transition into adolescence. Reward intensity during this developmental period predicted consumption frequency and severity of behavior undercontrol in midadolescence, which conjointly predicted SUD by early adulthood. This study demonstrated that SUD manifested by early adulthood culminates from the coaction of acquired cultural beliefs, social context facilitating access to addictive chemicals, and suboptimal psychological self-regulation. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":12089,"journal":{"name":"Experimental and clinical psychopharmacology","volume":" ","pages":"407-415"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12313405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time costs in the demand for cigarettes assessed using the cigarette purchase task-time (CPT-T).","authors":"Tommy Gunawan, David N Kearns, Alan Silberberg, Laura M Juliano","doi":"10.1037/pha0000777","DOIUrl":"10.1037/pha0000777","url":null,"abstract":"<p><p>Traditional cigarette purchase tasks (CPTs) assess cigarette demand as a function of monetary costs, neglecting the role of time as a cost in consumption decisions. This study introduces the cigarette purchase task-time (CPT-T), a novel measure designed to evaluate cigarette demand as a function of time costs. In Experiment 1, the participants (<i>N</i> = 50) completed the standard CPT with quantitative and probabilistic (CPT-P) response scales across three hypothetical delay conditions. Demand intensity decreased as delays increased, indicating that time functioned as a cost in cigarette consumption. In Experiment 2, the participants (<i>N</i> = 50) completed the CPT-P across three delay conditions and the CPT-T across three monetary conditions. Experiment 2 confirmed that increasing either time and monetary costs reduced demand intensity, breakpoints, and other demand indices, consistent with the law of demand. Experiment 3 evaluated the specificity and discriminant validity of the CPT-T by comparing demand across different reinforcers (cigarettes, potato chips, and toilet paper) between people who smoke (<i>n</i> = 50) and people who do not smoke (<i>n</i> = 50). People who smoke showed higher cigarette demand relative to people who do not smoke. Cigarette demand and toilet paper demand were higher than potato chips among people who smoke, but toilet paper demand was higher than cigarettes and potato chips for people who do not smoke, indicating that people who smoke view cigarettes as more essential. Together, these results showed that time acted as a cost in the demand for reinforcers. The CPT-T captured cigarette demand as a function of time costs and showed specificity and discriminant validity. These results open new theoretical avenues for our understanding of substance use disorders as a reinforcer pathology. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":12089,"journal":{"name":"Experimental and clinical psychopharmacology","volume":" ","pages":"381-395"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A brief online intervention for sleep problems and heavy drinking: Impacts on alcohol- and sleep-related problems.","authors":"Cristina N Abarno, Hannah M Chapman, Amy L Copeland","doi":"10.1037/pha0000783","DOIUrl":"10.1037/pha0000783","url":null,"abstract":"<p><p>There is growing evidence that poor sleep contributes to increased alcohol use and related impairment among college students (DeMartini & Fucito, 2014), with heavy drinking exacerbating these effects. Efforts to reduce this impact via online personalized feedback interventions (PFIs) have had limited success, and there is a dearth of research on attempts to simultaneously address these concerns among college students using brief, web-based interventions. The present study assessed intervention efficacy in addition to the impact of sleep disturbance on alcohol outcomes using a novel, brief, online PFI for sleep problems among college students who drink heavily. Participants were randomly assigned to one of the three interventions: PFI-Alcohol (<i>n</i> = 66), PFI-Alcohol-Sleep (<i>n</i> = 64), or assessment-only control (<i>n</i> = 66). Alcohol use, related impairment, and sleep problems decreased from baseline to 1-month follow-up under all conditions. However, participants under the control condition endorsed greater alcohol use during follow-up compared with intervention conditions. Notably, baseline insomnia symptoms predicted follow-up alcohol problems (but not use) when accounting for variance attributable to baseline negative affect, condition, and sex. More work is needed to examine the impact of brief online PFIs that concurrently target alcohol use and sleep problems among college students to determine its impact on reducing related-problems in this population. Results highlight the need for further investigation of the incorporation of sleep components within online alcohol PFIs to reduce heavy drinking and sleep problems among college students. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":12089,"journal":{"name":"Experimental and clinical psychopharmacology","volume":" ","pages":"371-380"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between public posting about alcohol on social networking sites and alcohol outcomes among non-college-attending young adults.","authors":"Lily Davidson, Megan Strowger, Benjamin Riordan, Nioud Mulugeta Gebru, Rose Marie Ward, Jennifer E Merrill","doi":"10.1037/pha0000767","DOIUrl":"10.1037/pha0000767","url":null,"abstract":"<p><p>There is potential to use public posts on social networking sites (SNS) to screen for problematic alcohol use. This study investigated how frequency of public posting about alcohol on SNS relates to alcohol outcomes among young adults (YA) not attending 4-year college. We also explored associations for racial/ethnic and gender subgroups. Participants were 501 non-college-attending YA, aged 18-29, living in the United States. Participants were recruited via Qualtrics Panels and completed measures of demographics, SNS use (past-3-month frequency of public posting about alcohol on Instagram, TikTok, \"X\"), and alcohol-related outcomes: heavy episodic drinking frequency (HED), high-intensity drinking episodes (HID), U.S. Alcohol Use Disorders Identification Test total (USAUDIT), and alcohol consequences. Regression models tested hypothesized associations between frequency of public posting and alcohol outcomes. Subsequent models assessed simple effects by race/ethnicity (Hispanic, Black, White) and gender (man, woman). Controlling for covariates, more frequent public alcohol-posting was associated with higher USAUDIT, HED frequency, and HID likelihood, not consequences. For Hispanic YA, posting was positively associated with all outcomes except consequences. For Black YA, posting was positively associated with USAUDIT and HID, not HED or consequences. For White YA, posting was positively associated with USAUDIT and HED, not HID or consequences. For women, posting was positively associated with USAUDIT total, HID, and consequences. For men, posting was positively associated with USAUDIT and HED. In conclusion, more frequent public alcohol-posting on SNS was positively associated with past-year alcohol use and problems, implying potential to screen for hazardous drinking via public SNS posts, among non-college-attending YA. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":12089,"journal":{"name":"Experimental and clinical psychopharmacology","volume":" ","pages":"352-360"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12313412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}