Jing Chen , Li Wei , Chun-mei Deng , Jing Xiong , Song-mei Chen , Ding Lu , Zhi-Hong Li , Yao Chen , Jun Xiao , Tian-wu Chen
{"title":"A liver CT based nomogram to preoperatively predict lung metastasis secondary to hepatic alveolar echinococcosis","authors":"Jing Chen , Li Wei , Chun-mei Deng , Jing Xiong , Song-mei Chen , Ding Lu , Zhi-Hong Li , Yao Chen , Jun Xiao , Tian-wu Chen","doi":"10.1016/j.ejrad.2024.111865","DOIUrl":"10.1016/j.ejrad.2024.111865","url":null,"abstract":"<div><h3>Purpose</h3><div>To develop a nomogram based on liver CT and clinical features to preoperatively predict lung metastasis (LM) secondary to hepatic alveolar echinococcosis (HAE).</div></div><div><h3>Methods</h3><div>A total of 291 consecutive HAE patients from Institution A undergoing preoperative abdominal contrast-enhanced CT and chest unenhanced CT were retrospectively reviewed, and were randomly divided into the training and internal validation sets at the 7:3 ratio. 82 consecutive patients from Institution B were enrolled as an external validation set. A nomogram was constructed based on the significant CT and clinical features of HAE from the training set selected by univariable and multivariable analyses to predict LM, and its predictive accuracy was assessed by area under the receiver operating characteristic curve (AUC) and Brier score. Decision-curve analysis was applied to evaluate the clinical effectiveness. This nomogram was verified in two independent validation sets.</div></div><div><h3>Results</h3><div>Eosinophil (odds ratio [OR] = 9.60; 95 % confidence interval [CI]: 1.80–51.11), lesion size (OR = 1.02; 95 %CI: 1.01–1.04), and moderate-severe invasion of inferior vena cava (IVC) (OR = 5.57; 95 %CI: 1.82–17.10) were independently associated with LM (all <em>P</em>-values < 0.05). The nomogram based on the three independent predictors displayed AUCs of 0.875 (95 %CI, 0.824–0.927), 0.872 (95 %CI, 0.787–0.957) and 0.836 (95 %CI, 0.729–0.943), and Brier score of 0.105, 0.1 and 0.118 in the training, internal validation and external validation sets, respectively. Decision-curve analysis showed good clinical utility.</div></div><div><h3>Conclusion</h3><div>A nomogram based on eosinophil, lesion size and moderate-severe invasion of IVC showed good ability and accuracy for preoperative prediction of LM due to HAE.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111865"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noam Nissan , Jeffrey S. Reiner, Victoria L. Mango, Hila Fruchtman-Brot , Rosa Elena Ochoa Albiztegui, Yuki Arita, Jill Gluskin , Tali Amir, Kimberly Feigin, Maxine S. Jochelson , Janice S. Sung
{"title":"Non-enhancing asymmetries on screening contrast-enhanced mammography: Is further diagnostic workup required?","authors":"Noam Nissan , Jeffrey S. Reiner, Victoria L. Mango, Hila Fruchtman-Brot , Rosa Elena Ochoa Albiztegui, Yuki Arita, Jill Gluskin , Tali Amir, Kimberly Feigin, Maxine S. Jochelson , Janice S. Sung","doi":"10.1016/j.ejrad.2024.111883","DOIUrl":"10.1016/j.ejrad.2024.111883","url":null,"abstract":"<div><h3>Objectives</h3><div>Asymmetries on screening contrast-enhanced mammography (CEM) often lead to patient recall. However, in diagnostic settings, negative CEM has effectively classified these as normal or benign, questioning the need for further workup of non-enhancing asymmetries (NEAs).</div></div><div><h3>Material and methods</h3><div>A computational search of all screening CEM examinations performed between December-2012 and June-2021 was conducted to identify cases reporting NEAs. Their diagnostic workup was reviewed, and the positive predictive value for cancer was statistically compared to that of enhancing asymmetries on screening CEMs.</div></div><div><h3>Results</h3><div>During the study period, 97 cases of 106 NEAs were identified among 3,482 screening CEM exams (2.8 %). NEAs were classified as asymmetry (n = 83), focal asymmetry (n = 22), and global asymmetry (n = 1), with no cases of developing asymmetry. The mean size of NEAs was 1.0 ± 0.7 cm (range: 0.3–4.9 cm). Diagnostic workup for NEAs included additional mammographic views (AMV) (n = 63), AMV plus ultrasound (n = 30), AMV plus MRI (n = 1), and all three modalities (n = 3), leading to four biopsies. None of the NEAs were malignant on follow-up, as opposed to enhancing asymmetries (P < 0.05).</div></div><div><h3>Conclusion</h3><div>NEAs detected on CEM were relatively uncommon and were usually investigated with additional mammographic views and US, yielding no cancer. Ruling out malignancy based on lack of enhancement without further workup may reduce patient recall rates and improve CEMs specificity.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111883"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lee O’Hora, Kirsten O’Brien, John Tuffy, Agnella Craig, Noelle Neville, Kay Sugrue, Margaret Keaveney, Emma O’Brien, Eimear Quinn, Sean Egan
{"title":"Establishing national diagnostic reference levels in fluoroscopy and fluoroscopically guided interventions in Ireland and comparing these with national diagnostic reference levels in Europe and internationally","authors":"Lee O’Hora, Kirsten O’Brien, John Tuffy, Agnella Craig, Noelle Neville, Kay Sugrue, Margaret Keaveney, Emma O’Brien, Eimear Quinn, Sean Egan","doi":"10.1016/j.ejrad.2024.111890","DOIUrl":"10.1016/j.ejrad.2024.111890","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this work was to establish national Irish diagnostic reference levels (DRLs) for a clinically representative and comprehensive list of clinical indications, anatomical regions, and common procedures for fluoroscopy and fluoroscopically guided interventions and compare these, where possible, to other DRLs established at a national level.</div></div><div><h3>Method</h3><div>A list of clinical indications, anatomical regions and common procedures was established. A national database of service providers was used to identify all medical radiological facilities providing fluoroscopy and fluoroscopically guided intervention services. These facilities were issued with an online survey. National Pka DRLs were set as the 75th percentile of the distribution of median values obtained. A national median dose was also established which is the 50th percentile of the median doses provided by facilities for the same patients and conditions as the national DRL value. The broad categorisation of equipment type was also considered. Where statistically significant differences were found between different detector types, detector specific national DRLs were established (flat panel detector and image intensifier specific DRLs).</div></div><div><h3>Results</h3><div>National Pka DRLs were established for 52 fluoroscopy and fluoroscopically guided intervention clinical indications, anatomical regions, and procedures. In addition, equipment specific (flat panel detector and image intensifier based systems) adult DRLs were established for the EVAR and lumbar puncture under fluoroscopy procedures. Paediatric DRLs were established for two fluoroscopy and fluoroscopically guided intervention clinical indications, anatomical regions, and procedures across various weight categories. Comparisons with other nationally set DRLs and other relevant literature suggest that Irish DRLs are typically lower than those established elsewhere.</div></div><div><h3>Conclusions</h3><div>This work provided a unique opportunity to establish national DRLs based on census data for a wide range of clinical indications, anatomical regions, and procedures across adult and paediatric fluoroscopy and fluoroscopically guided interventions. Where comparisons with other nationally established work was possible Irish values are largely below other DRLs.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111890"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142893365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mapping the values of radiology","authors":"Bjørn Hofmann","doi":"10.1016/j.ejrad.2024.111901","DOIUrl":"10.1016/j.ejrad.2024.111901","url":null,"abstract":"<div><div>Radiology is polyvalent, as it is valuable in many ways to many groups, such as to individuals, professionals, and populations. However, not all values are positive. While Value-Based HealthCare (VBHC) has moved the focus from volume-based to value-based health care and Value-Based Radiology (VBR) has highlighted a vast variety of values in radiology, such frameworks provide no measures to differentiate, assess, and balance the various values. Based on value theory this article provides a value map for radiology. The map can be helpful to a) identify and understand the complexity of values in radiology, b) differentiate and assess the values of radiology’s various tasks and aspects, c) to address potential value conflicts in radiology, and d) to maximize the positive and minimize its negative value. Mapping the values of radiology thus is crucial for understanding and increasing the importance of imaging.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111901"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Navigating the future of mammography: How women’s perceptions of AI may guide tomorrow’s screening practice","authors":"Sophia Zackrisson , Anetta Bolejko","doi":"10.1016/j.ejrad.2024.111870","DOIUrl":"10.1016/j.ejrad.2024.111870","url":null,"abstract":"","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111870"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ni Zhao , Anya Shi , Weile Huang , Jianan He , Dashuai Wang , Yongyu Zhang , Hui Guo , Bin Zhou , Hairun Gan , Pengfei Pang
{"title":"Three-dimensional volumetric CT image fusion and trans-abdominal US: Adjunct guidance to portal vein cannulation for TIPS","authors":"Ni Zhao , Anya Shi , Weile Huang , Jianan He , Dashuai Wang , Yongyu Zhang , Hui Guo , Bin Zhou , Hairun Gan , Pengfei Pang","doi":"10.1016/j.ejrad.2024.111875","DOIUrl":"10.1016/j.ejrad.2024.111875","url":null,"abstract":"<div><h3>Purpose</h3><div>To describe portal vein cannulation under adjunct guidance for transjugular intrahepatic portosystemic shunts (TIPS).</div></div><div><h3>Methods</h3><div>Medical records of 86 patients who underwent TIPS, including conventional TIPS, 3D volumetric CT image fusion (CT-fluoroscopy image fusion)-guided TIPS, and <em>trans</em>-abdominal ultrasound (US)-guided TIPS at our institute from March 2016 to June 2024 were reviewed. Baseline characteristics, clinical outcomes, and procedural data were analyzed.</div></div><div><h3>Results</h3><div>Technical success was achieved in 35 conventional TIPS patients (92.11 %), 20 CT-fluoroscopy image fusion-guided TIPS patients (95.24 %), and 26 transabdominal US-guided TIPS patients (96.30 %). Among patients who underwent a successful procedure, the procedural time and contrast usage were lower in the CT-fluoroscopy image fusion-guided and <em>trans</em>-abdominal US-guided TIPS groups than in the conventional group. There was a statistical significance in the cumulative fluoroscopic time between CT-fluoroscopy image fusion-guided TIPS and conventional TIPS groups (43.19 ± 14.92 vs 63.05 ± 30.33 min, <em>p = 0.012</em>). No immediate experienced complications were observed. Furthermore, the incidence of post-procedural complications among the three groups was not statistically different during follow-up.</div></div><div><h3>Conclusions</h3><div>CT-fluoroscopy image fusion and <em>trans</em>-abdominal US-guided portal vein cannulation are feasible, safe, and effective adjunct methods for patients undergoing TIPS. These methods provide shorter procedural time and lower contrast usage for TIPS placement.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111875"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"VI steps to achieve VI-RADS assessment","authors":"Sitthipong Srisajjakul , Patcharin Prapaisilp , Sirikan Bangchokdee","doi":"10.1016/j.ejrad.2024.111868","DOIUrl":"10.1016/j.ejrad.2024.111868","url":null,"abstract":"<div><div>Bladder cancer is categorized into nonmuscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC), distinguished by the presence of detrusor muscle invasion. Urothelial cell carcinoma is the most common subtype of bladder cancer. Transurethral resection of bladder tumor (TURBT) is the standard approach for staging and managing NMIBC, while radical cystectomy remains the cornerstone treatment for MIBC.</div><div>Multiparametric magnetic resonance imaging (mpMRI), comprising morphological imaging sequences (high-resolution T2-weighted images) and functional imaging sequences (dynamic contrast-enhanced images and diffusion-weighted images), serves as an ideal modality. It provides high-contrast resolution for visualizing bladder wall layers, thereby enabling proper and timely staging of bladder cancer. MRI can guide sampling resection and identify patients understaged after primary TURBT, facilitating appropriate surgical restaging.</div><div>In 2018, the Vesical Imaging Reporting and Data System (VI-RADS), implementing a 5-point scale, was developed to standardize MRI protocols and reporting criteria—including tumor location, size, morphology, and invasiveness. The aim of this article is to navigate through all the steps to achieve VI-RADS assessment and to discuss practical pearls and pitfalls in the use of mpMRI. This approach can aid in pre-TURBT prediction of muscle invasion, representing an important asset in bladder cancer staging.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111868"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bernd Erber , Anna Geßl , Paul Reidler , Hans Roland Dürr , Alexander Klein , Max Seidensticker , Moritz Wildgruber , Jens Ricke , Bastian Sabel
{"title":"Impact of reactive sclerosis on outcome of MR-HIFU for osteoid osteomas","authors":"Bernd Erber , Anna Geßl , Paul Reidler , Hans Roland Dürr , Alexander Klein , Max Seidensticker , Moritz Wildgruber , Jens Ricke , Bastian Sabel","doi":"10.1016/j.ejrad.2024.111902","DOIUrl":"10.1016/j.ejrad.2024.111902","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the influence of clinical and procedural factors, particularly the thickness of reactive sclerosis, on clinical outcome of MR-guided high-intensity focused ultrasound (MR-HIFU) for the treatment of symptomatic osteoid osteomas (OO) of the extremities.</div></div><div><h3>Materials and methods</h3><div>18 consecutive patients (median age 19.5y) with symptomatic OO of the extremities eligible for MR-HIFU were enrolled in this ongoing prospective study (German Clinical Trials Register; nr. DRKS00015448). The Functional Assessment of Cancer Therapy − Bone Pain (FACT-BP) score was used for evaluation of symptoms and quality of life parameters at 1-week, 2-week, 1-month, 6-month and 12-month follow-up (FU) after intervention. MRI was performed prior as well as, 6 and 12 months after intervention. Assessment included procedural and imaging parameters, with a specific focus on the thickness of the reactive sclerosis surrounding the nidus.</div></div><div><h3>Results</h3><div>Symptoms and quality of life parameters significantly improved between baseline and all FUs on the FACT-BP (mean score at baseline: 29.7; at 6-month-FU: 5.5; at 12-month-FU: 3.4, all p < 0.01). A strong correlation was found between scores of FACT-BP and the thickness of reactive sclerosis surrounding the nidus (r = 0.62 at 6-month-FU; p = 0.006) with an optimal cutoff of 0.6 cm identified for predicting a good clinical outcome.</div></div><div><h3>Conclusion</h3><div>MR-HIFU is an effective method for the treatment of symptomatic osteoid osteomas of the extremities in pediatric and adult patients, with the thickness of reactive sclerosis surrounding the nidus being a relevant factor influencing patient outcomes and emphasizing its importance in MR-HIFU assessment and planning.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111902"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hang Long , Binwei Hao , Yuxi Cao , Yaoyao Cai , Shuang Wei , Xiansheng Liu
{"title":"[18F]FDG PET/CT versus Dynamic Contrast-Enhanced CT for the diagnosis of solitary pulmonary Nodule: A Head-to-Head comparative Meta-Analysis","authors":"Hang Long , Binwei Hao , Yuxi Cao , Yaoyao Cai , Shuang Wei , Xiansheng Liu","doi":"10.1016/j.ejrad.2025.111916","DOIUrl":"10.1016/j.ejrad.2025.111916","url":null,"abstract":"<div><h3>Purpose</h3><div>This head-to-head comparative <em>meta</em>-analysis aimed to evaluate the comparative diagnostic efficacy of [<sup>18</sup>F]FDG PET/CT and dynamic contrast-enhanced CT(DCE-CT) for the differentiation between malignant and benign pulmonary nodules.</div></div><div><h3>Methods</h3><div>An extensive search was conducted in the PubMed, Embase, and Web of Science to identify available publications up to March 23, 2024. Studies were included if they evaluated the diagnostic efficacy of [<sup>18</sup>F]FDG PET/CT and DCE-CT for the characterization of pulmonary nodules. Sensitivity and specificity were assessed using the inverse variance method, followed by transformation via the Freeman-Tukey double inverse sine transformation. The quality of the included studies utilizing the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool.</div></div><div><h3>Results</h3><div>Seven articles involving 1,183 patients were included in the <em>meta</em>-analysis. The sensitivity of [<sup>18</sup>F]FDG PET/CT was comparable to that of DCE-CT (0.88 vs. 0.87, <em>P</em> = 0.95). Similarly, the specificity of [<sup>18</sup>F]FDG PET/CT was not significantly different from that of DCE-CT (0.63 vs. 0.54, <em>P</em> = 0.47). No significant publication bias was detected for any outcome (Egger’s test: all <em>P</em> > 0.05). For DCE-CT, <em>meta</em>-regression analysis identified the mean lesion size of pulmonary nodules (<20 mm vs. ≥ 20 mm, <em>P</em> = 0.01) as a potential source of heterogeneity. Meanwhile, the number of patients (<100 vs. ≥ 100, <em>P</em> < 0.01) for PET/CT may also contribute to the heterogeneity.</div></div><div><h3>Conclusions</h3><div>Our <em>meta</em>-analysis indicates that [<sup>18</sup>F]FDG PET/CT demonstrates similar sensitivity and specificity to DCE-CT for the diagnosis of pulmonary nodules. However, the number of the head-to-head studies were relatively small, further larger sample prospective research is required to confirm these findings.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111916"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Technical and clinical reasons for negative skin test results following intradermal testing of contrast media","authors":"Ingrid Böhm","doi":"10.1016/j.ejrad.2025.111939","DOIUrl":"10.1016/j.ejrad.2025.111939","url":null,"abstract":"","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111939"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}