European Journal of Radiology最新文献

{"title":"Workload of diagnostic radiologists in the foreseeable future based on recent (2024) scientific advances: Updated growth expectations","authors":"Thomas C. Kwee ,&nbsp;Robert M. Kwee","doi":"10.1016/j.ejrad.2025.112103","DOIUrl":"10.1016/j.ejrad.2025.112103","url":null,"abstract":"<div><h3>Purpose</h3><div>To assess the expected impact of the 2024 medical imaging literature on the workload of diagnostic radiologists.</div></div><div><h3>Methods</h3><div>A random sample of 416 articles on diagnostic imaging that was published in 2024 was reviewed by one radiologist working in an academic tertiary care center and another radiologist working in a non-academic general teaching hospital.</div></div><div><h3>Results</h3><div>In the academic tertiary care hospital setting, 56.5 % (235/416) of articles had the potential to directly impact patient care, of which 48.9 % (115/235) would increase workload, 48.1 % (113/235) would not change workload, 0.4 % (1/235) would decrease workload, and 2.6 % (6/235) had an unclear effect on workload. Studies with Artificial Intelligence (AI) as primary research area were significantly (<em>P</em> &lt; 0.001) more likely to increase workload compared to studies with another primary research area, with an Odds Ratio (OR) of 14.3 (95 % confidence interval [CI]: 4.2 to 48.2). In the non-academic general teaching hospital setting, 56.5 % (231/416) of articles had the potential to directly impact patient care, of which 48.9 % (113/231) would increase workload, 48.1 % (111/231) would not change workload, 0.4 % (1/231) would decrease workload, and 2.6 % (6/231) had an unclear effect on workload. Studies with AI as primary research area were significantly (<em>P</em> &lt; 0.001) more likely to increase workload compared to studies with another primary research area, with an OR of 13.7 (95 % CI: 4.1 to 46.5).</div></div><div><h3>Conclusion</h3><div>The workload of diagnostic radiologists is expected to increase based on recent (2024) scientific literature, and AI applications generally seem to have an aggravating effect on workload.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"187 ","pages":"Article 112103"},"PeriodicalIF":3.2,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging-based surveillance in patients with initially detected pancreatic cystic lesions","authors":"Hyo Jung Park ,&nbsp;Sehee Kim ,&nbsp;Sang Hyun Choi ,&nbsp;Jin Hee Kim ,&nbsp;Seung Soo Lee ,&nbsp;Hyoung Jung Kim ,&nbsp;Jae Ho Byun","doi":"10.1016/j.ejrad.2025.112102","DOIUrl":"10.1016/j.ejrad.2025.112102","url":null,"abstract":"<div><h3>Purpose</h3><div>To determine the long-term outcomes of pancreatic cystic lesions (PCLs) undergoing surveillance, and evaluate the associations between imaging monitoring plans and detection of malignant progression.</div></div><div><h3>Methods</h3><div>This retrospective observational study included patients with incidentally detected PCLs (0.5–4.0 cm) on MRI between January 2015 and December 2016. Imaging modalities, time intervals, cumulative number of imaging examinations, and occurrence of malignant progression were recorded. The impact of cumulative CT/MRI examinations on detection of malignant progression at 1, 2, and 3-years was assessed using Cox-regression analyses.</div></div><div><h3>Results</h3><div>A total of 911 patients (mean age, 68.8-years; 445 with intraductal papillary mucinous neoplasm [IPMN]) underwent an average of five examinations during follow-up (median, 45.0-months). All 20 cases of malignant progression occurred in patients with IPMN, increasing steadily over the maximum 9-year follow-up. The cumulative number of MRI examinations was significantly associated with detection of malignant progression at 1-year (hazard ratio [HR] = 1.40; P = 0.035), and 2-year (HR = 1.38; P = 0.047) landmark points, while CT showed no such association. The cumulative number of MRI examinations was associated with malignant progression at both 1-year (HR = 1.63; P = 0.007) and 2-year (HR = 1.59; P = 0.013) landmark points in 350 patients with IPMN without worrisome features, but not in 95 patients with IPMN with worrisome features.</div></div><div><h3>Conclusion</h3><div>Imaging surveillance of incidentally detected PCLs for detecting malignant progression should prioritize IPMNs. MRI-based surveillance would be beneficial in the initial 2-years, especially for patients with IPMN lacking worrisome features.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"187 ","pages":"Article 112102"},"PeriodicalIF":3.2,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143815458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-hypervascular pancreatic neuroendocrine neoplasms differentiation from CA19-9 negative pancreatic ductal adenocarcinomas based on contrast CT: A large sample series","authors":"Jinyin Zhang ,&nbsp;Qingquan Tan ,&nbsp;Yang Fan ,&nbsp;Liu Xiao ,&nbsp;Zhenjiang Zheng ,&nbsp;Keyu Li ,&nbsp;Wenyi Jing ,&nbsp;Haiyu Song ,&nbsp;Xubao Liu ,&nbsp;Chunlu Tan ,&nbsp;Xing Wang","doi":"10.1016/j.ejrad.2025.112095","DOIUrl":"10.1016/j.ejrad.2025.112095","url":null,"abstract":"<div><div>Propose: This study aims to evaluate the effectiveness of contrast-enhanced computed tomography (CT) in distinguishing non-hypervascular pancreatic neuroendocrine neoplasms (PNENs) from pancreatic ductal adenocarcinomas (PDACs) with a normal serum level of carbohydrate antigen 19-9 (CA19-9) levels.</div></div><div><h3>Methods</h3><div>This retrospective study included 134 patients with pathologically confirmed non-hypervascular PNENs and 128 patients with CA19-9-negative PDACs, all of whom underwent contrast-enhanced CT prior to surgery between January 2015 and March 2024. Following independent evaluation by two radiologists, qualitative features from both groups were extracted in the arterial and portal venous phase and subsequently compared using univariate and multivariate analysis.</div></div><div><h3>Results</h3><div>Patients with CA19-9 negative PDACs were significantly older than those with non-hypervascular PNENs (p &lt; 0.001), and the majority of PDACs were located in the head of the pancreas (p &lt; 0.01).Univariate analysis showed that non-hypervascular PNENs exhibited a higher frequency of well-defined tumor margins (p &lt; 0.001) and calcification (p = 0.032) and a lower frequency of local invasion (p &lt; 0.001), peripancreatic vascular invasion (p = 0.001), intra- or extrahepatic bile duct dilatation (p &lt; 0.001), distal main pancreatic duct dilatation (p &lt; 0.001), regional lymphadenopathy (p &lt; 0.001) and tumor homogeneity (p &lt; 0.001) when compared to CA19-9 negative PDACs. Multivariate analysis identified the absence of local invasion (Odds Ratio (OR) = 0.233; 95 % Confidence Internals (95 % CI):0.114–0.476; p &lt; 0.001), absence of peripancreatic vascular invasion (OR = 0.434; 95 % CI:0.217–0.870; p = 0.019), a normal distal main pancreatic duct diameter (OR = 0.398; 95 % CI:0.202–0.785; p = 0.008), absence of regional lymphadenopathy (OR = 0.455; 95 % CI:0.238–0.870; p = 0.017) and tumor heterogeneity (OR = 0.240; 95 % CI:0.126–0.456; p &lt; 0.001) as significant predictors of non-hypervascular PNENs. The area under the receiver operating characteristic curve for the radiological feature model was 0.829 based on logistic regression.</div></div><div><h3>Conclusions</h3><div>Qualitative features in contrast-enhanced CT images could be beneficial in differentially diagnosing non-hypervascular PNENs and CA19-9 negative PDACs.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"187 ","pages":"Article 112095"},"PeriodicalIF":3.2,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143808286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and feasibility of percutaneous pulsed electrical field ablation in multiple organs: A multi-center retrospective study☆","authors":"William H. Moore ,&nbsp;Mikhail Silk ,&nbsp;Priya Bhattacharji ,&nbsp;Bradley B. Pua ,&nbsp;Joseph Mammarappallil ,&nbsp;R. Ryan Meyerhoff ,&nbsp;Jonathan Kessler ,&nbsp;Jordan Tasse ,&nbsp;Dustin Gulizia","doi":"10.1016/j.ejrad.2025.112078","DOIUrl":"10.1016/j.ejrad.2025.112078","url":null,"abstract":"<div><h3>Purpose</h3><div>To assess the safety and feasibility of Pulsed Electrical Fields (PEF) ablation in various organs and patient populations.</div></div><div><h3>Materials and Methods</h3><div>This multi-center, retrospective study collected data from five academic medical centers on patients undergoing percutaneous PEF ablation, with a minimum of 30 days follow-up. Parameters assessed included demographics, treatment specifics, immediate adverse events, and survival rates. Procedures used CT or ultrasound guidance with a 19-gauge insulated needle and PEF probe.</div></div><div><h3>Results</h3><div>This study included 155 patients with a mean age of 60.7 years, predominantly with lung cancer (77/155). Most patients 85 % (131/155) had stage IV disease. The mean hospital stay post PEF was 0.3 days, with most discharged the same day. In lung procedures adverse events of pneumothorax occurred in 21.5 % of lung procedures, with 11.3 % requiring chest tube placements. No adverse events were observed in liver procedures. The 1-year overall survival rate for the entire cohort was 74.6 %, with patients with colorectal cancer having the highest survival rate of 89.7 %, and patient with sarcomas lowest at 18.0 %.</div></div><div><h3>Conclusion</h3><div>Percutaneous PEF is feasible to be performed across a variety of organs. Although difficult to compare with other modalities, this data suggests that PEF ablation is relatively safe. However, further prospective studies with larger sample sizes and comprehensive imaging are needed to confirm these findings and establish efficacy.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"187 ","pages":"Article 112078"},"PeriodicalIF":3.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fusion 3D T1/T2 MRI for diagnosing pelvic deep infiltrating endometriosis: a non-inferiority study","authors":"Alexandre Stolz,&nbsp;Lawrence Fabian Pupulim,&nbsp;María Rojas Soldado,&nbsp;Patrick Chabloz,&nbsp;Karen Kinkel","doi":"10.1016/j.ejrad.2025.112091","DOIUrl":"10.1016/j.ejrad.2025.112091","url":null,"abstract":"<div><div>Magnetic resonance imaging (MRI) is an essential non-invasive technique for diagnosing deep infiltrating endometriosis (DIE). Published studies have explored the value of high-resolution fat-suppressed 3D T1-weighted (T1w) and 3D T2-weighted (T2w) MRI in this topic. However, research on the fusion of these sequences in a merged ‘PET-scanner-like’ multiplanar reconstruction (Fusion 3D T1/T2) is still lacking.</div><div>Our primary objective was to assess whether the diagnostic accuracy of Fusion 3D T1/T2 was non-inferior to the state-of-the-art MRI protocol for diagnosing DIE. This standard protocol consists of 2D T2w images in various planes and axial T1w images displayed on a four-window screen (STANDARD). The non-inferiority margin was set at 2.5 %.</div><div>Fifty-nine pelvic MRI examinations for suspected endometriosis were interpreted independently by two radiologists with different experience levels (R#1 and R#2), randomly with both protocols. Results were compared with a consensus opinion from an expert panel. Interpretation time and inter-reader agreement were also evaluated.</div><div>Using the Fusion 3D T1/T2 protocol, R#1′s diagnostic accuracy for DIE was 94.74% (95%CI: 92.48–96.47) and R#2′s was 98.68% (95%CI: 97.31–99.47), both of which were non-inferior to the STANDARD protocol (R#1, 92.48%, 95%CI: 89.90–94.57; R#2, 96.43%, 95%CI: 94.48–97.84).</div><div>The Fusion 3D T1/T2 protocol reduced interpretation time by 24.5 % (<em>P</em> &lt; 0.001) compared to the STANDARD. Additionally, it improved inter-reader reproducibility, with a moderate level of agreement (kappa = 0.72; 95 % CI: 0.63–0.81), compared to the slight agreement (kappa = 0.47; 95 % CI: 0.34–0.59) observed with the STANDARD protocol.</div><div>In conclusion, Fusion 3D T1/T2 demonstrated non-inferior diagnostic accuracy compared to the current MRI standard protocol. It also improved reproducibility and reduced interpretation time, suggesting its potential as a valuable tool for diagnosing pelvic DIE.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"187 ","pages":"Article 112091"},"PeriodicalIF":3.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging of non-stenotic carotid plaque for embolic stroke of undetermined source","authors":"Ting Li ,&nbsp;Hui Liu ,&nbsp;Lijuan Wang ,&nbsp;Xiaolei Su ,&nbsp;Qiongling Hu ,&nbsp;Kang Li","doi":"10.1016/j.ejrad.2025.112097","DOIUrl":"10.1016/j.ejrad.2025.112097","url":null,"abstract":"<div><h3>Purpose</h3><div>Ischemic stroke is a significant cause of death and disability. Embolic Stroke of Undetermined Source (ESUS) accounts for a large proportion of acute ischemic strokes. A clear etiology is crucial for the treatment and prevention of stroke. The pathogenic mechanism of non-stenotic carotid plaque (NSCP) in ESUS is not yet fully understood. This study used computed tomographic angiography (CTA) to assess the correlation between NSCP and ESUS.</div></div><div><h3>Method</h3><div>Eighty-one patients with unilateral anterior circulation ESUS were retrospectively enrolled between June 2020 and June 2022. The prevalence of NSCP, degree of stenosis, plaque thickness, plaque type, plaque irregularity, plaque ulceration, focal areas of hypodensity within the plaque, and positive remodeling were evaluated in both carotid arteries on CTA. Univariate and multivariate logistic regression were used to determine the relationship between NSCP, plaque characteristics, and ipsilateral stroke.</div></div><div><h3>Results</h3><div>Among 81 patients with unilateral anterior circulation ESUS, the incidence of NCSP was significantly higher in the ipsilateral carotid artery than in the contralateral side (76.5 % vs. 60.5 %, P = 0.028). Plaque type, plaque thickness, plaque thickness &gt;3 mm, and focal areas of hypodensity within the plaque were remarkably different between two sides of carotid plaques (all <em>P</em> &lt; 0.05). In addition, multifactorial logistic regression showed that intraplaque hypodensity (aOR = 6.449 [95 % CI, 1.818–22.878]) and greater plaque thickness (aOR = 2.476 [95 % CI, 1.14–5.38]) were significantly associated with ESUS.</div></div><div><h3>Conclusions</h3><div>The prevalence of NSCP ipsilateral to stroke is higher in ESUS patients, and more complex plaque features were found on the ipsilateral side. Greater plaque thickness and hypodensity within the plaque were significantly associated with ESUS, and these plaques may be an important embolization source of ESUS.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"187 ","pages":"Article 112097"},"PeriodicalIF":3.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143808288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffusion MRI tractography with along-tract profiling reveals subtle neurodevelopmental differences between moderate and late preterm infants","authors":"Anouk S. Verschuur ,&nbsp;Chantal M.W. Tax ,&nbsp;Ingrid M. Nijholt ,&nbsp;Gerda van Wezel-Meijler ,&nbsp;Leonora Hendson ,&nbsp;Hussein Zein ,&nbsp;Jeanne Scotland ,&nbsp;Regan King ,&nbsp;Khorshid Mohammad ,&nbsp;Martijn F. Boomsma ,&nbsp;Alexander Leemans ,&nbsp;Lara M. Leijser","doi":"10.1016/j.ejrad.2025.112098","DOIUrl":"10.1016/j.ejrad.2025.112098","url":null,"abstract":"<div><h3>Purpose</h3><div>Moderately preterm (MP) infants (32–33 weeks’ gestation) are at increased risk for developmental problems compared to late preterm (LP) infants (34–36 weeks’ gestation). Fiber bundle tractography remains an unexplored avenue to understanding this risk-difference between MP and LP infants. This study aimed to examine along-tract profile differences between MP and LP infants at term-equivalent age (TEA).</div></div><div><h3>Methods</h3><div>Ninety-five infants (31 MP and 64 LP), born between November 2020 and March 2023, underwent MRI around TEA (40–44 weeks postmenstrual age). MRI included T2-weighted imaging and diffusion MRI (dMRI) with b-values 800 and 2000 s/mm² (single shell). dMRI scans were preprocessed to reduce common artifacts. For all infants, 15 fiber bundles were reconstructed using TractSeg and along-tract profiles, expressed as fractional anisotropy (FA) and mean diffusivity (MD), and were compared between MP and LP infants using tractometry.</div></div><div><h3>Results</h3><div>Reconstructions with TractSeg demonstrated shape, position, and orientation of fiber bundles consistent with known neuroanatomy. FA and MD profiles were not significantly different between MP and LP infants. However, alternating trends towards along-tract profile differences between MP and LP infants were observed for multiple bundles. Wide 95% confidence intervals indicated substantial variability in fiber bundle organization within groups.</div></div><div><h3>Conclusion</h3><div>Although not significant, along-tract differences between MP and LP infants suggest subtle alterations in white matter maturation. These findings indicate along-tract variability as potential focus for future research aimed at uncovering the mechanisms underlying early maturational differences and their potential role in later neurodevelopmental challenges encountered in moderate-late preterm infants.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"187 ","pages":"Article 112098"},"PeriodicalIF":3.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143815460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the effectiveness of ultrasound-guided corticosteroid injection treatment in plantar fasciitis using shear wave elastography","authors":"Enes Gurun ,&nbsp;Mesut Ozturk ,&nbsp;Ismet Mirac Cakir ,&nbsp;Ahmet Serhat Genc ,&nbsp;Ipek Ozkan ,&nbsp;Dilara Erdogan ,&nbsp;Ahmet Emin Okutan ,&nbsp;Omer Bozduman","doi":"10.1016/j.ejrad.2025.112092","DOIUrl":"10.1016/j.ejrad.2025.112092","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the effectiveness of ultrasound-guided corticosteroid injection in patients with plantar fasciitis (PF) and assess changes in shear wave elastography (SWE) measurements and clinical outcomes.</div></div><div><h3>Methods</h3><div>Between March and August 2024, 66 patients (aged 27 to 67 years) diagnosed with PF were enrolled in the study. Plantar fascia thickness, shear wave velocity (SWV) in meters per second (m/s), and Young’s modulus in kilopascals (kPa) were measured before the injection and at a 1-month follow-up. The correlation of these measurements with the Visual Analog Scale (VAS, 0–10) and the American Orthopedic Foot and Ankle Society (AOFAS) scores was analyzed.</div></div><div><h3>Results</h3><div>Before treatment, the plantar fascia thickness, SWV, and Young’s modulus were recorded as 5.02 ± 0.66 mm, 2.37 ± 0.22 m/s, and 18.64 ± 3.28 kPa, respectively. At the 1-month follow-up, these values significantly changed to 3.53 ± 0.39 mm, 3.39 ± 0.32 m/s, and 35.49 ± 7.25 kPa, respectively (p &lt; 0.001 for all). A significant reduction in plantar fascia thickness and a significant increase in SWV and Young’s modulus were observed. Additionally, improvements in VAS and AOFAS scores were strongly correlated with increases in SWV and Young’s modulus (VAS-m/s: r = -0.632, p = 0.011; AOFAS-m/s: r = 0.695, p = 0.001; VAS-kPa: r = −0.673, p &lt; 0.001; AOFAS-kPa: r = 0.798, p &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>Ultrasound-guided corticosteroid injection significantly increased plantar fascia stiffness, and SWE measurements strongly correlated with clinical improvements. SWE proves to be a valuable adjunctive tool for evaluating treatment response in PF.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"187 ","pages":"Article 112092"},"PeriodicalIF":3.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing trends in patients undergoing recurrent CT examinations and cumulative doses","authors":"Andrew E. Ferretti,&nbsp;Nathaniel D. Mercaldo,&nbsp;Xinhua Li,&nbsp;Madan M. Rehani","doi":"10.1016/j.ejrad.2025.112099","DOIUrl":"10.1016/j.ejrad.2025.112099","url":null,"abstract":"<div><h3>Purpose</h3><div>Recent research has enhanced our understanding of the number of patients receiving relatively high radiation doses (≥100 mSv) through recurrent CT examinations. However, there is a paucity of information on temporal trends. This study elucidates these trends over the past 11 years.</div></div><div><h3>Methods</h3><div>We retrieved data on CT exams conducted from 2013 to 2023 from our hospital’s dose-management system. We analyzed the number of patients undergoing recurrent CT examinations, calculated the median cumulative effective dose (CED), and assessed the frequency of patients receiving doses of ≥ 50 mSv and ≥ 100 mSv. Generalized linear models that accounted for autocorrelation via Newey-West covariance estimates and non-linearities due to the COVID-19 pandemic were employed to quantify temporal trends.</div></div><div><h3>Results</h3><div>Among 403,997 patients in 11 years, 46.3 % had 1 CT exam, 53.7 % received ≥ 2 exams, 20.3 % received ≥ 5 exams, and 8.3 % had ≥ 10 exams, with 6.6 % having CEDs ≥ 100 mSv. The rate of recurrent exams decreased post-2020 (incident rate ratio, IRR: 1.029, 95 % CI 1.025, 1.033). The median CED increased post-2020 relative to pre-2020 (difference in annual changes: −0.102, 95 % CI −0.119, −0.085). Patients with new annual doses ≥ 100 mSv decreased post-pandemic (IRR: 0.976, 95 % CI 0.955, 0.997).</div></div><div><h3>Conclusions</h3><div>In this study examining temporal trends, the percentage of patients undergoing multiple CT examinations has changed since 2020, with a shift from an increasing to a decreasing trend in those receiving cumulative doses ≥ 100 mSv per year. This suggests an alteration in imaging practices or patient demographics since 2020, providing valuable insights to inform policymaking.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"187 ","pages":"Article 112099"},"PeriodicalIF":3.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143808234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative unveiling of mucinous ovarian cancer subtypes: Clinical and CT features","authors":"Pamela Causa Andrieu ,&nbsp;Dina Hamdan ,&nbsp;Sara Hassanzadeh ,&nbsp;Ridin Balakrishnan ,&nbsp;Lee Rodriguez ,&nbsp;Junting Zheng ,&nbsp;Maria Clara Fernandes ,&nbsp;Aaron Praiss ,&nbsp;Natalie Gangai ,&nbsp;Marinela Capanu ,&nbsp;Lora H Ellenson ,&nbsp;Yulia Lakhman ,&nbsp;Dennis S. Chi ,&nbsp;Hedvig Hricak ,&nbsp;Natally Horvat","doi":"10.1016/j.ejrad.2025.112090","DOIUrl":"10.1016/j.ejrad.2025.112090","url":null,"abstract":"<div><h3>Objectives</h3><div>To compare the frequency, clinical, imaging, and survival characteristics of mucinous ovarian carcinoma (MOC) growth pattern subtypes.</div></div><div><h3>Background</h3><div>According to ESGO 2024 guidelines, fertility-sparing surgery can be considered for stages IA and IC1 expansile MOC due to their excellent prognoses and low recurrence risk. The ability to diagnose MOC subtypes preoperatively would aid treatment planning. However, variables for preoperatively distinguishing MOC subtypes have not been established.</div></div><div><h3>Methods</h3><div>This IRB-approved, retrospective, single-center study included consecutive patients (≥18 years) with pre-treatment CT from 01/2000–12/2020 and pathological diagnosis of MOC. One experienced radiologist interpreted all CTs, reviewing challenging cases with a senior radiologist. Clinical (age, CA-125, FIGO stage), outcome (local recurrence, distant metastasis, death from cancer/unrelated cause), and CT (laterality, size, mass type, calcifications, adenopathy, peritoneal/serosal implants, ascites) were compared (p &lt; 0.05).</div></div><div><h3>Results</h3><div>Of 24 patients with MOC, 50 % (n = 12) had expansile disease. Compared to infiltrative MOC, expansile MOC appeared more often at stage I (92 % vs. 58 %), at younger ages (median, 45 vs. 68 years; p = 0.03), and with lower CA-125 (median, 18 vs. 78 ng/mL). At CT, 75 % of expansile vs. 58 % of infiltrative cases were multilocular masses with solid components and ill-defined borders; 25 % of infiltrative, but no expansile cases, were bilateral; 25 % of patients with infiltrative but none with expansile MOC experienced early recurrence, eventually dying of cancer. P-values were &gt; 0.10 for all differences but age, potentially due to the small sample.</div></div><div><h3>Conclusions</h3><div>Although CT features of MOC subtypes were similar, expansile MOC presented in younger patients with lower CA-125 levels, was more often diagnosed at stage I, and was uniformly unilateral.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"187 ","pages":"Article 112090"},"PeriodicalIF":3.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143808235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}