European Journal of Radiology最新文献

{"title":"Diagnostic performance of biparametric MRI according to prostate imaging quality (PI-QUAL) version 2: Analysis of Multi-Institutional Data","authors":"Jeong In Shin,&nbsp;Kye Jin Park,&nbsp;Mi Yeon Park,&nbsp;Mi-Hyun Kim,&nbsp;Sung Bin Park,&nbsp;Jeong Kon Kim","doi":"10.1016/j.ejrad.2025.112209","DOIUrl":"10.1016/j.ejrad.2025.112209","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the impact of image quality on the diagnostic performance of biparametric MRI (bpMRI) for detecting clinically significant prostate cancer (csPCa).</div></div><div><h3>Patients and Methods</h3><div>This retrospective study included patients who underwent bpMRI at outside imaging facilities and were referred to our tertiary centre between January 2020 and November 2021. The image quality of bpMRI was assessed by two radiologists in consensus using Prostate Imaging Quality Score version 2 (PI-QUAL v2). Technical parameters of T2WI and DWI were extracted, and their associations with imaging quality criteria were evaluated. Sensitivity, specificity, and positive and negative predictive values for detecting csPCa were compared according to PI-QUAL v2 scores.</div></div><div><h3>Results</h3><div>Among 112 men who underwent bpMRI at 69 different imaging facilities, 47 (42.0 %) MRIs were considered not applicable for PI-QUAL v2 scoring. Of the remaining MRIs, 30 (26.8 %), 17 (15.2 %), and and 18 (16.1 %) were assigned PI-QUAL v2 scores of 1, 2, and 3, respectively. MRIs with PI-QUAL v2 scores ≤ 1 demonstrated significantly lower sensitivity (74.3 %) than those with scores of 2 or 3 (100.0 %; <em>P</em> = 0.045). In-plane resolution on T2WI and the number of <em>b</em> values on DWI were significantly associated with image quality assessment (<em>P</em> = 0.037 and 0.028).</div></div><div><h3>Conclusions</h3><div>The diagnostic accuracy of bpMRI for detecting csPCa is influenced by image quality, as assessed by the PI-QUAL v2 scoring system. Adequate in-plane resolution on T2WI and the use of at least three <em>b</em> values on DWI should be emphasised to achieve optimal image quality and diagnostic performance.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"189 ","pages":"Article 112209"},"PeriodicalIF":3.2,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144166450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal T1ρ quantification in chronic hepatitis B: from fibrosis staging to pegylated interferon-α therapeutic response tracking","authors":"Xin-Gui Peng,&nbsp;Yufei Zhao,&nbsp;Zhi Qin,&nbsp;Yang Jiang,&nbsp;Jingyue Dai,&nbsp;Ying Cui","doi":"10.1016/j.ejrad.2025.112203","DOIUrl":"10.1016/j.ejrad.2025.112203","url":null,"abstract":"<div><h3>Rationale and objectives</h3><div>To investigate liver tissue alterations across chronic hepatitis B (CHB) progression stages and monitor therapeutic changes following pegylated interferon-α (PEG-IFNα) therapy using T₁ρ magnetic resonance imaging (MRI).</div></div><div><h3>Materials and methods</h3><div>This prospective study enrolled 93 CHB patients stratified by histological severity: 44 mild, 26 moderate, and 23 severe cases. All patients underwent liver biopsy and T₁ρ MRI at baseline, followed by 48 weeks of PEG-IFNα therapy. 36 patients completed post-treatment T₁ρ MRI. A control cohort of 23 healthy volunteers received baseline MRI scans. Hepatic T₁ρ relaxation times were compared across subgroups and correlated with histopathological parameters (inflammation grade, fibrosis stage), serum biomarkers (alanine aminotransferase [ALT], aspartate aminotransferase [AST], total bilirubin [TBIL], direct bilirubin [DBIL], cholinesterase [CHE]), and non-invasive indices (fibrosis-4 index [FIB-4]). Statistical analyses included Spearman’s correlation and linear regression.</div></div><div><h3>Results</h3><div>The mild CHB group showed elevated T₁ρ relaxation time (43.94 ± 4.88 ms) versus healthy controls (39.05 ± 3.07 ms; <em>P</em> = 0.028), with progressive increases in moderate (48.21 ± 5.78 ms; <em>P</em> = 0.022 vs mild) and severe subgroups (53.99 ± 5.78 ms; <em>P</em> &lt; 0.001 vs moderate). All patient groups differed significantly from controls (all <em>P</em> &lt; 0.001). T₁ρ relaxation times exhibited strong positive correlations with histopathological progression (R² = 0.77 for fibrosis stage, R² = 0.50 for inflammation grade; both <em>P</em> &lt; 0.001) and moderate correlations with liver function parameters (ALT: R² = 0.18; AST: R² = 0.21) and synthetic markers (CHE: R² = 0.24). Post-therapeutic T₁ρ values decreased significantly compared to baseline (48.99 ± 8.05 ms vs. 43.57 ± 7.20 ms, <em>P</em> = 0.014).</div></div><div><h3>Conclusion</h3><div>T₁ρ MRI provides a promising non-invasive tool for assessing liver disease severity and monitoring treatment-related changes in CHB patients.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"190 ","pages":"Article 112203"},"PeriodicalIF":3.2,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144229631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between pericoronary fat attenuation index and quantitative plaque components in newly identified coronary plaques","authors":"Runzhi Zhang ,&nbsp;Wenjing Zhao ,&nbsp;Zehui Tang ,&nbsp;Yan Xu ,&nbsp;Hongyan Xie ,&nbsp;Chuangwei Wei ,&nbsp;Dongting Liu ,&nbsp;Wei Dong ,&nbsp;Jiayi Liu ,&nbsp;Lei Xu ,&nbsp;Zhaoying Wen ,&nbsp;Nan Zhang","doi":"10.1016/j.ejrad.2025.112206","DOIUrl":"10.1016/j.ejrad.2025.112206","url":null,"abstract":"<div><h3>Purpose</h3><div>This study investigates the correlation between fat attenuation index (FAI) and plaque components before and after coronary plaque formation in humans.</div></div><div><h3>Methods</h3><div>This retrospective study included 249 patients who developed newly identified coronary plaques after two coronary computed tomography angiography (CCTA) examinations, with the first yielding normal results. Vessels with newly identified plaques were categorized into the new plaque group, while others formed the no new plaque group. A control group of 50 patients with consistently normal CCTA results was also included. The new plaque group was further divided into stable FAI and progressive FAI groups based on changes in FAI.</div></div><div><h3>Results</h3><div>Before plaque formation, baseline FAI was highest in the new plaque group [(−80 (−84，-77) HU]. Baseline FAI was positively correlated with plaque volume, necrotic core volume, fibrofatty volume, and necrotic core percentage at both patient and vessel levels while showing a negative association with fibrous volume percentage (<em>P</em> &lt; 0.05). After plaque formation, the percentage of necrotic core volume and diabetes mellitus were independent determinants of FAI increase in the patient level [OR: 1.31 (95 % CI: 1.12–––1.53) and OR: 3.07 (95 % CI: 1.14–––8.28), respectively]. At the vessel level, the percentage of necrotic core volume and fibrous volume were independent determinants of FAI increase [OR: 1.33 (95 % CI: 1.16–––1.53) and OR: 0.98 (95 % CI: 0.96–––0.99), respectively].</div></div><div><h3>Conclusion</h3><div>FAI was found to interact with the volume and components of newly formed coronary plaques, especially the necrotic core. A higher baseline FAI was associated with necrotic core formation, and the development of necrotic cores further increased FAI. Conversely, the formation of fibrous components appeared to mitigate the increase in FAI.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"190 ","pages":"Article 112206"},"PeriodicalIF":3.2,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plaque and stent distinction using an experimental silicon-based photon-counting CT: An experimental and clinical comparison with conventional energy-integrated detector CT","authors":"Emma Verelst ,&nbsp;Hakån Almqvist ,&nbsp;Staffan Holmin ,&nbsp;Gert Van Gompel ,&nbsp;Hans Koenraad Nieboer ,&nbsp;Frans Vandenbergh ,&nbsp;Johan De Mey ,&nbsp;Dominic Crotty ,&nbsp;Paul Deak ,&nbsp;Nico Buls","doi":"10.1016/j.ejrad.2025.112207","DOIUrl":"10.1016/j.ejrad.2025.112207","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare plaque-stent interface using an experimental Silicon-based photon-counting CT (Si-PCCT) with a conventional energy-integrating detector CT (EIDCT).</div></div><div><h3>Methods</h3><div>A human-resected and stented artery was embedded centrally into an agar-water phantom and scanned in a Si-PCCT and an EIDCT using a similar scan technique targeting a CT volumetric dose index (CTDI_vol) of 9 mGy. Images were reconstructed using equivalent settings at 150 mm and 50 mm field-of-view (150FOV, 50FOV). Plaque-stent distinction, stent diameter measurement accuracy and blooming were quantitatively and qualitatively assessed using a 5-point Likert scale. Result comparisons between systems and FOVs were evaluated with a <em>t</em>-test and a Wilcoxon signed-rank test with inter-reader agreement assessed using intra-class correlation (ICC). Additionally, EIDCT and Si-PCCT images from a single clinical carotid angiography case were compared.</div></div><div><h3>Results</h3><div>Si-PCCT enabled improved plaque-stent contrast and reduced blooming (<em>p &lt; 0.001</em>) at both FOVs, whereas diameter measurement accuracy was only improved at 50FOV (<em>p = 0.003</em>), compared to EIDCT. 150FOV Si-PCCT images were preferred over EIDCT images forstent appearance (<em>p = 0.001</em>), plaque appearance (<em>p &lt; 0.001</em>), stent-plaque distinction (p <em>= 0.002</em>) and blooming (<em>p = 0.001</em>). 50FOV showed similar trends. 50FOV EIDCT images enabled improved plaque-stent contrast (<em>p = 0.046</em>), reduced blooming (<em>p &lt; 0.001</em>), and improved stent appearance (<em>p = 0.025</em>). For Si-PCCT, no improvements were observed at 50FOV. Quantitative and qualitative ICC was 0.93 and 0.96, respectivelyThe experimental findings are reflected in the evaluation of the patient case.</div></div><div><h3>Conclusion</h3><div>This study demonstrates the potential of Si-PCCT to improve image contrast and spatial resolution, enabling improved assessment of plaque and stent in an experimental phantom and a clinical patient case.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"189 ","pages":"Article 112207"},"PeriodicalIF":3.2,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decreased wall shear stress on 4D-flow-MRI is associated with wall instability of unruptured intracranial aneurysm","authors":"Qichang Fu ,&nbsp;Xinmei Ma ,&nbsp;Linghao Li ,&nbsp;Wanjun Xia ,&nbsp;Shanshan Xie ,&nbsp;Jumatay Biekan ,&nbsp;Mengzhu Wang ,&nbsp;Jianfeng Bao ,&nbsp;Junying Cheng ,&nbsp;Yong Zhang ,&nbsp;Sheng Guan ,&nbsp;Jingliang Cheng","doi":"10.1016/j.ejrad.2025.112200","DOIUrl":"10.1016/j.ejrad.2025.112200","url":null,"abstract":"<div><h3>Background and purpose</h3><div>The wall instability of unruptured intracranial aneurysms (UIAs) is associated with aneurysm growth or rupture. The wall shear stress (WSS) of 4D-flow-MRI can indicate hemodynamic abnormalities on the aneurysm wall. Aneurysm wall enhancement (AWE) of vessel wall MRI (VWI) and volume transfer constant (K^trans) of dynamic contrast-enhanced MRI (DCE-MRI) can indicate inflammation and permeability changes of the unstable aneurysm wall. We hypothesize that the WSS of UIAs is not only associated with AWE and K^trans but also with the risk of growth or rupture derived from the ELAPSS or PHASES scores of the aneurysm.</div></div><div><h3>Materials and methods</h3><div>A cross-sectional retrospective analysis was performed on patients with UIAs who underwent 3.0 T VWI, DCE-MRI, and 4D-flow-MRI in our hospital from January 2018 to October 2023. AWE, K^trans, and WSS were obtained by VWI, DCE-MRI, and 4D-flow MRI, respectively. AWE pattern (AWEP) and wall enhancement index (WEI) were used to evaluate AWE. 3- and 5-year aneurysm growth risk and 5-year rupture risk were predicted based on ELAPSS and PHASES scores, respectively. Correlations between parameters were assessed using Spearman’s correlation coefficient or logistic regression.</div></div><div><h3>Results</h3><div>Ninety-six aneurysms in 78 patients (53 women) were included in the study. WSS differed across AWEP subgroups (<em>p</em> &lt; 0.001). WSS was negatively correlated with AWEP, WEI, and K^trans (<em>rs</em> = −0.35, <em>rs</em> = −0.44, and <em>rs</em> = −0.25; <em>p</em> &lt; 0.001). Multiple logistic regression indicated that decreased WSS was associated with higher odds of AWE (OR: 0.65, 95 % CI: 0.48–0.87). WSS was negatively correlated with the 3- and 5-year growth risk and the 5-year risk of rupture (<em>rs</em> = −0.47, <em>rs</em> = −0.44, and <em>rs</em> = −0.50; <em>p</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>WSS on 4D-flow-MRI of aneurysms is inversely associated with AWEP, WEI, and K^trans and growth and rupture risk. The decrease in WSS on 4D-flow-MRI may provide valuable information for assessing aneurysm wall instability.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"190 ","pages":"Article 112200"},"PeriodicalIF":3.2,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144242104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cumulative dose: A simple infographic for referrers and patients","authors":"Madan M. Rehani ,&nbsp;Anjaneya Kathait ,&nbsp;Denis Remedios","doi":"10.1016/j.ejrad.2025.112202","DOIUrl":"10.1016/j.ejrad.2025.112202","url":null,"abstract":"<div><div>Communicating radiation risks effectively is critical in imaging examinations, especially for ensuring the benefit-risk justification among radiologists, medical physicists, referrers, radiation technologists, and patients. Imaging modalities such as CT, fluoroscopic guided interventions, and PET/CT pose challenges due to high cumulative radiation exposure in patients who require recurrent imaging. In recent years there has been a strong emphasis on assessing the cumulative effective doses (CED) in patients who undergo recurrent imaging for disease surveillance. In addition, while referral guidelines of the Royal College of Radiologists (RCR) and the American College of Radiology (ACR) have used symbolic representations like trefoil radiation symbols to simplify dose communication, there is a lack of similar efforts to communicate cumulative doses. While absolute dose metrics like millisieverts (mSv) or milligray (mGy) are scientifically essential, they often fail to provide intuitive understanding for non-specialists. We wish to extend the concept of radiation symbol use for communicating CED. The stacking of the trefoil symbol to represent cumulative dose has been proposed in this article by taking one symbol to represent 50 mSv. This approach can be built into referral guidelines to facilitate informed decision-making for chronic conditions requiring lifelong imaging and supports risk communication with patients. Incorporating cumulative dose symbols into referral guidelines and clinical workflows will provide a practical step toward optimizing radiation use while safeguarding patients against potential long-term effects. Such advancements align with the growing emphasis on patient-centric care and evidence based imaging practices.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"189 ","pages":"Article 112202"},"PeriodicalIF":3.2,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144166682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Large language models into radiology workflow: Impact of generating personalized report templates from summary","authors":"Amit Gupta ,&nbsp;Manzoor Hussain ,&nbsp;Kondaveeti Nikhileshwar ,&nbsp;Ashish Rastogi ,&nbsp;Krithika Rangarajan","doi":"10.1016/j.ejrad.2025.112198","DOIUrl":"10.1016/j.ejrad.2025.112198","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate feasibility of large language models (LLMs) to convert radiologist-generated report summaries into personalized report templates, and assess its impact on scan reporting time and quality.</div></div><div><h3>Materials and Methods</h3><div>In this retrospective study, 100 CT scans from oncology patients were randomly divided into two equal sets. Two radiologists generated conventional reports for one set and summary reports for the other, and vice versa. Three LLMs − GPT-4, Google Gemini, and Claude Opus − generated complete reports from the summaries using institution-specific generic templates. Two expert radiologists qualitatively evaluated the radiologist summaries and LLM-generated reports using the ACR RADPEER scoring system, using conventional radiologist reports as reference. Reporting time for conventional versus summary-based reports was compared, and LLM-generated reports were analyzed for errors. Quantitative similarity and linguistic metrics were computed to assess report alignment across models with the original radiologist-generated report summaries. Statistical analyses were performed using Python 3.0 to identify significant differences in reporting times, error rates and quantitative metrics.</div></div><div><h3>Results</h3><div>The average reporting time was significantly shorter for summary method (6.76 min) compared to conventional method (8.95 min) (p &lt; 0.005). Among the 100 radiologist summaries, 10 received RADPEER scores worse than 1, with three deemed to have clinically significant discrepancies. Only one LLM-generated report received a worse RADPEER score than its corresponding summary. Error frequencies among LLM-generated reports showed no significant differences across models, with template-related errors being most common (χ² = 1.146, p = 0.564). Quantitative analysis indicated significant differences in similarity and linguistic metrics among the three LLMs (p &lt; 0.05), reflecting unique generation patterns.</div></div><div><h3>Conclusion</h3><div>Summary-based scan reporting along with use of LLMs to generate complete personalized report templates can shorten reporting time while maintaining the report quality. However, there remains a need for human oversight to address errors in the generated reports.</div></div><div><h3>Relevance Statement</h3><div>Summary-based reporting of radiological studies along with the use of large language models to generate tailored reports using generic templates has the potential to make the workflow more efficient by shortening the reporting time while maintaining the quality of reporting.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"189 ","pages":"Article 112198"},"PeriodicalIF":3.2,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144138523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allergological evaluation of hypersensitivity reactions after administration of contrast agents: What the radiologist needs to know","authors":"Francisco Vega ,&nbsp;Aart J. van der Molen ,&nbsp;Maria Ruiz-Calatayud ,&nbsp;Aitana Alberdi ,&nbsp;Maria Catalá ,&nbsp;Carlos Blanco-Mota ,&nbsp;Annick A.J.M van de Ven ,&nbsp;José J. Laguna ,&nbsp;Carmen Sebastia","doi":"10.1016/j.ejrad.2025.112194","DOIUrl":"10.1016/j.ejrad.2025.112194","url":null,"abstract":"<div><h3>Objective</h3><div>To familiarize radiologists with the methodology used in the assessment and management of hypersensitivity reactions to contrast agents.</div></div><div><h3>Methods</h3><div>This review provides diagnostic tools for the appropriate identification this type of reactions, including a checklist of key clinical items and a proposed algorithm to differentiate hypersensitivity reactions from nonspecific reactions and to assess their severity. It also outlines the main <em>in vitro</em> techniques (specific IgE, basophil activation test, mast cell activation test, lymphoblastic transformation test, and ELISpot) and <em>in vivo</em> procedures (skin tests and drug provocation tests) used to identify the culprit contrast agent and guide the selection of a safe alternative.</div></div><div><h3>Results</h3><div>Although premedication is commonly used, its effectiveness is limited. Administering an alternative contras agent is a more effective strategy, but empirical selection carries a risk of recurrence. Allergy testing enables safer selection of an alternative agent. Integrating allergy evaluation into radiological practice can improve patient safety and outcomes in patients with a history of previous reactions.</div></div><div><h3>Conclusion</h3><div>Allergological techniques are valuable tools that support radiologists in the safe management of patients with hypersensitivity reaction to contrast agent, particularly in cases requiring re-exposure. The article concludes by presenting a diagnostic algorithm for both immediate and delayed reactions.</div></div><div><h3>Clinical relevance statement</h3><div>Switching to an alternative contrast agent is the most effective way to prevent a new hypersensitivity reaction. Radiologists should be familiar with the <em>in vivo</em> and in vitro techniques used in the allergy work-up to select a safe alternative agent.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"190 ","pages":"Article 112194"},"PeriodicalIF":3.2,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144242100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The predictive value of 18F-FDG PET/CT radiomics for pleural invasion in non-small cell lung cancer","authors":"Annan Zhang ,&nbsp;Meixin Zhao ,&nbsp;Xiangxing Kong ,&nbsp;Weifang Zhang ,&nbsp;Xiaoyan Hou ,&nbsp;Zhi Yang ,&nbsp;Xiangxi Meng ,&nbsp;Nan Li","doi":"10.1016/j.ejrad.2025.112199","DOIUrl":"10.1016/j.ejrad.2025.112199","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to develop and validate a PET/CT radiomics fusion model for preoperative predicting pleural invasion (PI) in non-small cell lung cancer (NSCLC) patients.</div></div><div><h3>Methods</h3><div>Data from Center A were divided into a training set (n = 260) and an internal validation set (n = 111), while data from Center B (n = 99) served as the external validation set. Radiomic features were extracted using PyRadiomics. Six feature screening methods and 12 machine learning methods were used to build clinical, PET/CT imaging, and radiomics fusion models. The best-performing model was selected based on accuracy, sensitivity, specificity, and area under the curve (AUC). A nomogram was created using logistic regression with clinical, PET/CT features, and Rad_score.</div></div><div><h3>Results</h3><div>The PET/CT radiomics fusion model exhibited superior predictive performance. In the internal validation set, it achieved an accuracy of 0.90, sensitivity of 0.88, specificity of 0.92, and AUC of 0.95 (95% CI 0.91–0.99). These metrics were significantly higher than those of the PET/CT imaging model (accuracy 0.83, sensitivity 0.83, specificity 0.82, AUC 0.85) and clinical model (accuracy 0.65, sensitivity 0.70, specificity 0.59, AUC 0.78). In the external validation set, the model demonstrated an accuracy of 0.81, sensitivity of 0.81, specificity of 0.81, and AUC of 0.85 (95% CI 0.77–0.94), outperforming the PET/CT imaging model (accuracy 0.76, sensitivity 0.75, specificity 0.77, AUC 0.80) and clinical model (accuracy 0.68, sensitivity 0.67, specificity 0.68, AUC 0.76). The nomogram showed excellent calibration, with a C index of 0.98 in the test set, 0.95 in the internal validation set, and 0.91 in the external validation set.</div></div><div><h3>Conclusion</h3><div>The PET/CT radiomics fusion model significantly improves PI prediction accuracy in NSCLC.</div><div><strong>Critical relevance statement:</strong>Pleural invasion is a critical prognostic factor in lung cancer and a challenge for preoperative CT evaluation. PET/CT radiomics fusion model has the highest predictive value in predicting PI of lung cancer.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"190 ","pages":"Article 112199"},"PeriodicalIF":3.2,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascular lesions of head and neck region: A pictorial review","authors":"Fahime Azizinik ,&nbsp;Sheida Javadi ,&nbsp;Faezeh Khorasanizadeh ,&nbsp;Fatemeh Shakki Katouli ,&nbsp;Reza Majidazar","doi":"10.1016/j.ejrad.2025.112190","DOIUrl":"10.1016/j.ejrad.2025.112190","url":null,"abstract":"<div><div>Vascular lesions in the head and neck region encompass a wide spectrum of malformations and tumors, ranging from hemangiomas to arteriovenous fistulas. The International Society for the Study of Vascular Anomalies classification system categorizes these anomalies into vascular tumors and malformations. Vascular tumors are further divided into benign, borderline, and malignant types, while vascular malformations are classified based on flow characteristics as high or low flow. Accurate delineation of these lesions is crucial due to their clinical implications, particularly their location and potential involvement of adjacent structures. Imaging modalities such as ultrasound, computed tomography, magnetic resonance imaging, and digital subtraction angiography play a vital role in diagnosis, surgical planning, and follow-up. Ultrasound is useful for superficial lesions, while computed tomography and magnetic resonance imaging provide detailed information on deep-seated anomalies. Vascular tumors include benign lesions like hemangiomas and pyogenic granuloma, borderline tumors such as hemangioendothelioma, and malignant tumors like angiosarcoma and Kaposi sarcoma. Vascular malformations include venous, lymphatic, capillary, arteriovenous malformations and combined lesions like lymphangiohemangioma. Each type has distinct imaging features, with magnetic resonance imaging being particularly valuable for assessing soft tissue involvement and lesion extent. This review highlights the importance of imaging in the diagnosis and management of head and neck vascular anomalies, emphasizing the need for a multidisciplinary approach to optimize patient outcomes.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"189 ","pages":"Article 112190"},"PeriodicalIF":3.2,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144134647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}