European Journal of Applied Physiology最新文献

{"title":"Durability in recreational runners: effects of 90-min low-intensity exercise on the running speed at the lactate threshold.","authors":"Olli-Pekka Nuuttila, Vesa Laatikainen-Raussi, Krista Vohlakari, Iida Laatikainen-Raussi, Johanna K Ihalainen","doi":"10.1007/s00421-024-05631-y","DOIUrl":"10.1007/s00421-024-05631-y","url":null,"abstract":"<p><strong>Purpose: </strong>Recent studies have suggested that the capability to resist deterioration of physiological characteristics could be an independent factor contributing to endurance performance. This study aimed at investigating whether prolonged low-intensity exercise induces shifts in the lactate threshold, and whether fatigue-induced changes differ between the sexes.</p><p><strong>Methods: </strong>A total of 31 (15 females) recreational runners performed an incremental treadmill test and a 90-min low-intensity exercise (LIT90) on two separate occasions. The LIT90 was performed at 90% of the first lactate threshold speed (LT1v), derived from the incremental treadmill test. The LT1v was determined from a 5-stage (3 min) submaximal threshold test (SubmaxLT), performed before and after LIT90. The SubmaxLTs were followed by a 10/5 reactivity jump test. Respiratory gases, heart rate (HR), and HR-derived detrended fluctuation analysis alpha 1 (DFA-a1) were assessed every 15 min during the LIT90.</p><p><strong>Results: </strong>A significant decrease (p < 0.01) was observed in the LT1v in females (- 5.8 ± 4.4%) and in males (- 5.3 ± 6.4%). The HR increased (p < 0.001) similarly in females (5.9 ± 3.1%) and in males (5.5 ± 3.6%) during the LIT90, while energy expenditure increased (3.1 ± 4.5%, p = 0.013) in females but remained unchanged in males (0.9 ± 3.1%). Change in DFA-a1 during the LIT90 was the only marker that correlated significantly with the relative change of LT1v (r = 0.463, p = 0.013).</p><p><strong>Conclusion: </strong>LIT90 induced significant decreases in the LT1v, and the changes were comparable between sexes. DFA-a1 could be a potential intra-session marker of durability.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":"697-705"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11889008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuromuscular characteristics of eccentric, concentric and isometric contractions of the knee extensors.","authors":"Cassio V Ruas, Janet L Taylor, Christopher Latella, G Gregory Haff, Kazunori Nosaka","doi":"10.1007/s00421-024-05626-9","DOIUrl":"10.1007/s00421-024-05626-9","url":null,"abstract":"<p><strong>Purpose: </strong>We compared voluntary drive and corticospinal responses during eccentric (ECC), isometric (ISOM) and concentric (CON) muscle contractions to shed light on neurophysiological mechanisms underpinning the lower voluntary drive in a greater force production in ECC than other contractions.</p><p><strong>Methods: </strong>Sixteen participants (20-33 years) performed ISOM and isokinetic (30°/s) CON and ECC knee extensor contractions (110°-40° knee flexion) in which electromyographic activity (EMG) was recorded from vastus lateralis. Voluntary activation (VA) was measured during ISOM, CON and ECC maximal voluntary contractions (MVCs). Transcranial magnetic stimulation elicited motor-evoked potentials (MEPs) and corticospinal silent periods (CSP) during MVCs and submaximal (30%) contractions, and short-interval intracortical inhibition (SICI) in submaximal contractions.</p><p><strong>Results: </strong>MVC torque was greater (P < 0.01) during ECC (302.6 ± 90.0 Nm) than ISOM (269.8 ± 81.5 Nm) and CON (235.4 ± 78.6 Nm), but VA was lower (P < 0.01) for ECC (68.4 ± 14.9%) than ISOM (78.3 ± 13.1%) and CON (80.7 ± 15.4%). In addition, EMG/torque was lower (P < 0.02) for ECC (1.9 ± 1.1 μV^.Nm^-1) than ISOM (2.2 ± 1.2 μV.Nm^-1) and CON (2.7 ± 1.6 μV^.Nm^-1), CSP was shorter (p < 0.04) for ECC (0.097 ± 0.03 s) than ISOM (0.109 ± 0.02 s) and CON (0.109 ± 0.03 s), and MEP amplitude was lower (P < 0.01) for ECC (3.46 ± 1.67 mV) than ISOM (4.21 ± 2.33 mV) and CON (4.01 ± 2.06 mV). Similar results were found for EMG/torque and CSP during 30% contractions, but MEP and SICI showed no differences among contractions (p > 0.05).</p><p><strong>Conclusions: </strong>The lower voluntary drive indicated by reduced VA during ECC may be partly explained by lower corticospinal excitability, while the shorter CSP may reflect extra muscle spindle excitation of the motoneurons from vastus lateralis muscle lengthening.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":"671-686"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11889023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142377808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Confidence intervals estimator of the kinetic parameters: do its reliability depend on the assembling method of the oxygen uptakes?","authors":"Maria Pia Francescato, Valentina Cettolo","doi":"10.1007/s00421-024-05629-6","DOIUrl":"10.1007/s00421-024-05629-6","url":null,"abstract":"<p><p>Gas exchange data acquired repeatedly under the same exercise conditions are assembled together to improve the kinetic parameters of breath-by-breath oxygen uptake. The latter are provided by the non-linear regression procedure, together with the corresponding estimators of the width of the Confidence Intervals (i.e., the Asymptotic Standard Errors; ASEs). We tested, for two different assembling procedures, whether the range of values identified by the ASE actually correspond to the 95% Confidence Interval. Ten O₂ uptake responses were acquired on 10 healthy volunteers performing a square-wave moderate-intensity exercise. Kinetic parameters were estimated running the non-linear regression with a mono-exponential model on an increasingly greater number of responses (Nr, from 1 to 10), assembled together using the \"stacking\" and the \"1-s-bins\" procedures. Kinetic values obtained assembling together the 10 repetitions were assumed as \"true\" values. The time constant was not affected by Nr or by the assembling procedure (ANOVA; p>0.54 and p>0.16, respectively). The corresponding ASE decreased according to Nr (ANOVA; p=0.000), being significantly smaller for the \"1-s-bins\" procedure compared to the \"stacking\" one (ANOVA; p<0.001). Excluding 20s at the start of the fitting window, the range of values identified with the ASE provided by the \"1-s-bins\" and the \"stacking\" procedures included the \"true\" value in 85% and in 95% of cases, respectively. The \"stacking\" procedure should be preferred since it yielded ASEs for the time constant that provided a range of values satisfying the statistical meaning of the width of the Confidence Intervals, at the given degree of probability.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":"781-791"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11889014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"No evidence of improvements in energy metabolism after 1 week of nitrate and citrulline co-supplementation in elite rowers.","authors":"Aitor Viribay, Juan M A Alcantara, Iker López, Juan Mielgo-Ayuso, Arkaitz Castañeda-Babarro","doi":"10.1007/s00421-024-05636-7","DOIUrl":"10.1007/s00421-024-05636-7","url":null,"abstract":"<p><strong>Purpose: </strong>Citrulline (CIT) and beetroot extract (BR) supplements positively impacts exercise performance in elite rowers. However, its influence on metabolic outcomes such as whole-body volumes of oxygen consumption (VO₂) and carbon dioxide production (VCO₂), substrate oxidation, energy expenditure (EE), and gross efficiency remains unknown. We studied the effects of 1 week of daily co-supplementation of 3.5 g BR (500 mg NO₃^-) plus 6 g CIT on VO₂ and VCO₂ kinetics, substrate utilization, EE, and gross efficiency in elite male rowers compared to a placebo and to a BR supplementation.</p><p><strong>Methods: </strong>Twenty elite rowers participated in this randomized, double-blind, placebo-controlled crossover trial completing 1 week of supplementation in each group of study: Placebo (PLAG); BRG; and BR-CITG. Efficiency (70% VO_2max) and performance (incremental maximal) tests were performed, and gas-exchange data were collected via indirect calorimetry.</p><p><strong>Results: </strong>Analysis of covariance (ANCOVA) showed no mean between-condition differences on respiratory exchange ratio (RER), EE, and gross efficiency in the efficiency test (all P > 0.06), and in the performance test (all P > 0.28). Moreover, in both tests no interaction Time × Supplement effects were observed for VO₂, VCO₂, RER, EE, substrate oxidation, and, gross efficiency (all P > 0.12).</p><p><strong>Conclusion: </strong>After 1 week, no effects on energy metabolism and substrate utilization were observed after the daily co-ingestion of BR extract plus CIT supplement, therefore longer (> 7 days) and higher doses of supplementation might be needed to influence metabolism.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":"715-728"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of glossopharyngeal insufflation and complete exhalation on breath-hold performance and physiological parameters in elite skin divers.","authors":"Dimitrios I Bourdas, Nickos D Geladas","doi":"10.1007/s00421-024-05632-x","DOIUrl":"10.1007/s00421-024-05632-x","url":null,"abstract":"<p><strong>Purpose: </strong>This study examined the physiological responses of ten elite divers to normal breathing (BHn), glossopharyngeal inhalation (BHi), and complete exhalation (BHe) prior to five maximal breath-hold (BH) efforts.</p><p><strong>Methods: </strong>Breath-hold time (BHT), hemological variables, mean arterial pressure (MAP), other hemodynamic indices, and diaphragmatic activity (DA) were recorded. During BHs, phases were identified as easy-going (EPh: minimal DA), struggling (SPh: increased DA), PhI (MAP transition), PhII (MAP stabilization), and PhIII (steep MAP increase).</p><p><strong>Results: </strong>BHi significantly extended BHT (309.14 ± 12.91 s) compared to BHn (288.77 ± 10.99 s) and BHe (151.18 ± 10.94 s) (P = 0.001). BHT, EPh, and SPh in BHi increased by 7.05%, 2.57%, and 11.08% over BHn, respectively. PhIII appeared earlier in BHe than in other conditions (P < 0.001) and accounted for 47.07%, 44.96%, and 60.18% of BHT in BHn, BHi, and BHe, respectively. SPh comprised 47.10%, 46.01%, and 45.13% of BHT in BHn, BHi, and BHe, respectively, with SPh onset coinciding with PhIII onset in BHn and BHi but not in BHe. Bradycardia was more pronounced in BHe, maintaining better stroke volume. No significant differences in red blood cells or maximal MAP were noted across conditions.</p><p><strong>Conclusion: </strong>Glossopharyngeal inhalation improves BHT and extends EPh and SPh durations. PhIII onset is linked to SPh in BHn and BHi but not in BHe. BHe triggers an earlier MAP rise, leading to stronger parasympathetic responses. Despite similar maximal MAP across conditions, the higher BHT and tissue hypoxemia in BHi and BHn suggest MAP is a key limiting factor in apnoea.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":"753-767"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of the optimal dose and dosing strategy for effective L-menthol oral rinsing during exercise in hot environments.","authors":"Owen Jeffries, Godi Jibi, Joe Clark, Martin Barwood, Mark Waldron","doi":"10.1007/s00421-024-05609-w","DOIUrl":"10.1007/s00421-024-05609-w","url":null,"abstract":"<p><strong>Purpose: </strong>This multi-study programme investigated the optimal concentration of L-menthol delivered as an oral mouth rinse to modulate thermo-behaviour during exercise in a hot environment (35 °C).</p><p><strong>Method: </strong>In study 1, 38 participants completed a survey to establish an effective and tolerable range of L-menthol concentration. 31 participants completed an RPE-protocol examining 1. the dose-response effect of L-menthol mouth rinse on exercise performance (n = 16) and 2. the temporal effectiveness of administering L-menthol in an incremental and decremental dosing pattern (n = 15). Power output, heart rate, body core temperature and thermal sensation were reported throughout.</p><p><strong>Results: </strong>The optimal menthol concentration for peak power was between 0.01 and 0.1% (~ 6% increase, P < 0.05) and 0.5% (~ 9% increase, P < 0.05) with respect to control. Work completed was increased at 0.01% (~ 5%, P < 0.05), at 0.1% (~ 3%, P < 0.05) and had a detrimental effect at 0.5% (- 10% decrease, P < 0.05). There were no differences between an ascending dose protocol (0.01 to 0.5%), descending dose protocol (0.5-0.01%) or a constant 0.01% dose protocol. There were no reported differences in body core temperature or heart rate across trials (P > 0.05).</p><p><strong>Conclusion: </strong>The optimal dose of L-menthol when delivered via oral rinsing is between 0.01 and 0.1%. At lower concentrations, L-menthol appears to be less effective and at higher concentrations (> 0.5%) L-menthol appears to elicit greater irritation and may not positively modulate thermo-behaviour during exercise in a hot environment.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":"629-638"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11889024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142377806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The work-recovery cycle of kidney strain and inflammation in sugarcane workers following repeat heat exposure at work and at home.","authors":"Rebekah A I Lucas, Erik Hansson, Bethany D Skinner, Esteban Arias-Monge, Catharina Wesseling, Ulf Ekström, Ilana Weiss, Zoey E Castellón, Scarlette Poveda, Fatima I Cerda-Granados, William Jose Martinez-Cuadra, Jason Glaser, David H Wegman, Kristina Jakobsson","doi":"10.1007/s00421-024-05610-3","DOIUrl":"10.1007/s00421-024-05610-3","url":null,"abstract":"<p><strong>Purpose: </strong>To examine heat exposure at work and home and the work-recovery cycle and temporal variation of kidney strain, muscle injury and inflammation biomarkers in sugarcane workers.</p><p><strong>Methods: </strong>20 male sugarcane workers (age: 33 ± 7 years) with a workplace Rest.Shade.Hydration (RSH) intervention were observed over 4 days, at the end (18 h post-shift recovery) and beginning of a work week (42 h post-shift recovery). Measures included work intensity (heart rate), gastro-intestinal temperature, estimated body core temperature (using heart rate), fluid consumption, pre- and post-work blood and urine samples, physical activity (accelerometery) away from work, plus ambient heat exposure at work and home.</p><p><strong>Results: </strong>On workdays, workers awakened at approx. 02:40 after 5 h sleep in ~ 30 °C. Across work shifts, daily average WBGT ranged from 26 to 29 °C (cooler than normal) and average workload intensity ranged from 55 to 58%HR_max. Workers reported consuming ~ 8 L of water and ~ 4 × 300 mL bags of electrolyte fluid each day. Serum creatinine, cystatin C and creatine phosphokinase markedly increased post-work and decreased during recovery; serum potassium did the opposite (all p < 0.01). Biomarker concentration changes were similar between recovery periods (18 h vs. 42 h; all p > 0.27). C-reactive protein was the highest at the end of the work week (p = 0.01).</p><p><strong>Conclusion: </strong>Despite RSH intervention, cross-shift kidney strain was marked (recovering overnight) and systemic inflammation increased over the work week. Thus, biomonitoring of kidney function in occupational populations should be performed before a work shift at any point in the work week. This is essential knowledge for field studies and surveillance.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":"639-652"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11889006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142377819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modelling to decipher physiological determinants of improved muscle endurance.","authors":"Nicolas Place, Håkan Westerblad","doi":"10.1007/s00421-024-05590-4","DOIUrl":"10.1007/s00421-024-05590-4","url":null,"abstract":"","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":"591-592"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute ergogenic effects of repetitive maximal breath-holding maneuvers on hematological and physiological responses: a graded exercise test investigation.","authors":"Yiannis Christoulas, Dimitrios I Bourdas, Yiannis Michailidis, Ilias Mavrovouniotis, Thomas I Metaxas, Kosmas Christoulas, Nikolaos A Koutlianos","doi":"10.1007/s00421-024-05624-x","DOIUrl":"10.1007/s00421-024-05624-x","url":null,"abstract":"<p><strong>Purpose: </strong>Repetitive maximal breath-holds (BHs or apneas) have been noted to induce advantageous hematological and blood buffering changes. Building on this, the hypothesis was formulated that the execution of repeated maximal BH efforts might lead to subsequent enhancements in performance during a time-to-exhaustion test.</p><p><strong>Methods: </strong>This study investigated the acute effects of five static maximal breath-holding maneuvers conducted with face immersion in cold water (10 °C) on subsequent graded exercise test (GET) performance. Seventeen well-trained participants completed a GET on a motorized treadmill under two randomized cross-over conditions: baseline measurement (CON) and after five repeated maximal breath-holding efforts (EXP).</p><p><strong>Results: </strong>The GET protocol consists of incremental increases in speed until exhaustion. After the fifth breath-hold, participants in the EXP condition exhibited significant (P < 0.05) increases in hematocrit, hemoglobin concentration, red blood cell count, and muscle deoxygenation, accompanied by a reduction in blood lactate concentration (4.09 ± 2.21%, 3.9 ± 1.76%, 3.96 ± 2.1%, 81.48 ± 23.83%, and 15.22 ± 17.64%, respectively), compared to CON. During GET, the EXP condition showed a significantly (P < 0.05) delayed onset time of the second ventilatory threshold (3.14 ± 5.85%) and (P < 0.05) increased time to exhaustion (0.75 ± 1.02%).</p><p><strong>Conclusion: </strong>This evidence suggests that repeated maximal static breath-holding maneuvers enhance the oxygen delivery system by increasing the circulation of reserve red blood cells, heightened muscle oxygen deoxygenation, enhanced aerobic metabolism utilization, and postponing the transition from aerobic to anaerobic metabolism, implying a potential ergogenic effect. While pre-exercise breath-holding shows promise for improving time-to-exhaustion and optimizing subsequent distance running performance, further in-depth investigation is essential to fully elucidate the underlying mechanistic factors.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":"739-751"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of ischemic preconditioning on physical fitness and performance: a meta-analysis in healthy adults.","authors":"Zhen Chen, Wenqiang Wu, Lijun Qiang, Congshuai Wang, Zhijian He, Yufeng Wang","doi":"10.1007/s00421-024-05633-w","DOIUrl":"10.1007/s00421-024-05633-w","url":null,"abstract":"<p><strong>Purpose: </strong>This meta-analysis aims to assess the impact of ischemic preconditioning (IPC) on physical fitness and performance, with a focus on its specific role in aerobic endurance, anaerobic endurance, explosive power and strength.</p><p><strong>Methods: </strong>Systematic searches were conducted across multiple databases (CNKI, CBM, Cochrane Library, Web of Science, PubMed, and Embase) up to September 6, 2023. We included studies that employed randomized controlled trial methods and sham ischemic preconditioning as the placebo group, and two reviewers independently screened literature and extracted data, using Review Manager 5.3 for analysis.</p><p><strong>Results: </strong>This meta-analysis comprises 27 articles with 405 individuals, selected according to specified criteria. IPC significantly increased the blood lactate concentration after anaerobic speed endurance exercise (MD = 0.74, P = 0.03), the blood lactate concentration after incremental exercise (MD = 0.49, P = 0.04), the blood lactate concentration after muscular endurance exercise (MD = 0.68, P = 0.02), and the one-repetition maximum (MD = 1.38, P = 0.00001). Furthermore, it also significantly shortened completion time of the exercises primarily powered by glycolysis (MD =  - 0.49, P = 0.01) and completion time of the exercises primarily powered by aerobic system (MD =  - 7.27, P = 0.05), while marginally prolonging time to exhaustion (MD = 22.68, P = 0.08). However, IPC had no significant effect on maximum oxygen uptake, blood lactate concentration in fixed-load aerobic endurance exercise, peak power, or peak aerobic power, nor on completion time of the exercises primarily powered by phosphagen system.</p><p><strong>Conclusion: </strong>IPC could serve as a method to enhance physical performance, particularly for exercises primarily powered by aerobic system and glycolysis. Future research might explore how various cycles, locations, and widths of IPC affect the physical performance of participants with different activity levels.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":"805-821"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}