European Journal of Applied Physiology最新文献

{"title":"A modified step-ramp-step protocol to prescribe constant-speed exercise in treadmill running.","authors":"Robin Faricier, Lorenzo Micheli, Nasimi A Guluzade, Juan M Murias, Daniel A Keir","doi":"10.1007/s00421-024-05542-y","DOIUrl":"https://doi.org/10.1007/s00421-024-05542-y","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated whether a running-adapted version of the cycling-based \"step-ramp-step\" (SRS) protocol would improve prediction of <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂ in treadmill exercise compared to the traditional prescriptive approach.</p><p><strong>Methods: </strong>Fourteen healthy individuals (6 females; 25 ± 6 years; 66.1 ± 12.7 kg) performed a treadmill-based SRS protocol including a ramp-incremental test to task failure followed by two constant-speed bouts within the moderate-(MOD_step-below estimated lactate threshold; θ_LT), and heavy-intensity domains (HVY_step-between θ_LT and respiratory compensation point; RCP). Using the uncorrected <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂-to-speed relationship from the ramp exercise, three constant-speed bouts were performed at 40-50% between: baseline and θ_LT (CSE_MOD); θ_LT and RCP (CSE_HVY); and RCP and peak (CSE_SEV). For CSE_MOD, CSE_HVY, and CSE_SEV measured end-exercise <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂ was compared to predicted <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂ based on the: (i) \"SRS-corrected\" <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂-to-speed relationship (where MOD_step and HVY_step were used to adjust the <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂ relative to speed); and (ii) linear \"uncorrected\" data.</p><p><strong>Results: </strong>Average treadmill speeds for CSE_MOD and CSE_HVY were 7.8 ± 0.8 and 11.0 ± 1.4 km·h^-1, respectively, eliciting end-exercise <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂ of 1979 ± 390 and 2574 ± 540 mL·min^-1. End-exercise <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂ values were not different compared to SRS-predicted <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂ at CSE_MOD (mean difference: 5 ± 166 mL·min^-1; p = 0.912) and CSE_HVY (20 ± 128 mL·min^-1; p = 0.568). The linear \"uncorrected\" estimates were not different for CSE_MOD (- 91 ± 172 mL·min^-1; p = 0.068) but lower for CSE_HVY (- 195 ± 146 mL·min^-1; p < 0.001). For CSE_SEV (running speed: 13.8 ± 1.7 km·h^-1), the end-exercise <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂ was not different from peak <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂ achieved during the ramp (3027 ± 682 vs. 2979 ± 655 mL·min^-1; p = 0.231).</p><p><strong>Conclusion: </strong>In healthy individuals, the SRS protocol more accurately predicts speeds for a target <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂ compared to traditiona","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polarized running training adapted to versus contrary to the menstrual cycle phases has similar effects on endurance performance and cardiovascular parameters.","authors":"Claudia Kubica, Sascha Ketelhut, Claudio Renato Nigg","doi":"10.1007/s00421-024-05545-9","DOIUrl":"https://doi.org/10.1007/s00421-024-05545-9","url":null,"abstract":"<p><strong>Purpose: </strong>This study compared the effects of polarized running training adapted to the menstrual cycle (MC) phases versus polarized training adapted contrary to the MC on endurance performance and cardiovascular parameters.</p><p><strong>Methods: </strong>Thirty-three naturally menstruating, moderately trained females (age: 26 ± 4 years; BMI: 22.3 ± 3.2 kg/m²; <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O_2max/rel: 40.35 ± 4.61 ml/min/kg) were randomly assigned to a control (CON) and intervention (INT) group. Both groups participated in a load-matched eight-week running training intervention. In the INT, high-intensity sessions were aligned with the mid and late follicular phase, low-intensity sessions with the early and mid-luteal phase, and recovery with the late luteal and early follicular phase. In the CON, high-intensity sessions were matched to the late luteal and early follicular phase, and recovery to the mid and late follicular phase. Endurance performance and cardiovascular parameters were assessed at baseline and after the intervention.</p><p><strong>Results: </strong>Twenty-six females completed the intervention. A repeated measures ANOVA determined no time × group interaction effect for any parameter. A significant time effect was found for maximal oxygen uptake (F(1,12) = 18.753, p = 0.005, η_p² = 0.630), the velocity at the ventilatory threshold one (F(1,12) = 10.704, p = 0.007, η_p² = 0.493) and two (F(1,12) = 7.746, p = .018, η_p² = .413).</p><p><strong>Conclusion: </strong>The training intervention improved endurance performance in both groups, with no further benefit observed from the MC-adapted polarized training in a group-based analysis. Replications with an extended intervention period, a larger sample size, and a more reliable MC determination are warranted.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning predicts peak oxygen uptake and peak power output for customizing cardiopulmonary exercise testing using non-exercise features.","authors":"Charlotte Wenzel, Thomas Liebig, Adrian Swoboda, Rika Smolareck, Marit L Schlagheck, David Walzik, Andreas Groll, Richie P Goulding, Philipp Zimmer","doi":"10.1007/s00421-024-05543-x","DOIUrl":"https://doi.org/10.1007/s00421-024-05543-x","url":null,"abstract":"<p><strong>Purpose: </strong>Cardiopulmonary exercise testing (CPET) is considered the gold standard for assessing cardiorespiratory fitness. To ensure consistent performance of each test, it is necessary to adapt the power increase of the test protocol to the physical characteristics of each individual. This study aimed to use machine learning models to determine individualized ramp protocols based on non-exercise features. We hypothesized that machine learning models will predict peak oxygen uptake ( <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O_2peak) and peak power output (PPO) more accurately than conventional multiple linear regression (MLR).</p><p><strong>Methods: </strong>The cross-sectional study was conducted with 274 (♀168, ♂106) participants who performed CPET on a cycle ergometer. Machine learning models and multiple linear regression were used to predict <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O_2peak and PPO using non-exercise features. The accuracy of the models was compared using criteria such as root mean square error (RMSE). Shapley additive explanation (SHAP) was applied to determine the feature importance.</p><p><strong>Results: </strong>The most accurate machine learning model was the random forest (RMSE: 6.52 ml/kg/min [95% CI 5.21-8.17]) for <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O_2peak prediction and the gradient boosting regression (RMSE: 43watts [95% CI 35-52]) for PPO prediction. Compared to the MLR, the machine learning models reduced the RMSE by up to 28% and 22% for prediction of <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O_2peak and PPO, respectively. Furthermore, SHAP ranked body composition data such as skeletal muscle mass and extracellular water as the most impactful features.</p><p><strong>Conclusion: </strong>Machine learning models predict <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O_2peak and PPO more accurately than MLR and can be used to individualize CPET protocols. Features that provide information about the participant's body composition contribute most to the improvement of these predictions.</p><p><strong>Trial registration number: </strong>DRKS00031401 (6 March 2023, retrospectively registered).</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141491434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the biomechanics and fatigue patterns of eccentric quasi-isometric muscle actions in the knee extensors and flexors.","authors":"Urška Ličen, Dustin J Oranchuk, Žiga Kozinc","doi":"10.1007/s00421-024-05544-w","DOIUrl":"https://doi.org/10.1007/s00421-024-05544-w","url":null,"abstract":"<p><strong>Purpose: </strong>Eccentric quasi-isometric (EQI) resistance training is emerging as a promising option in sports medicine and rehabilitation. Despite prior research on EQI contractions in quadriceps and biceps brachii, their use in hamstring injury contexts is underexplored. Therefore, our study examines and contrasts the biomechanics and fatigue effects of EQI training on knee extensors and flexors.</p><p><strong>Methods: </strong>Following familiarization, 16 healthy, active participants (9 men, 7 women; 23.5 ± 2.6 years, 72.1 ± 12.8 kg, 173.4 ± 10.7 cm) performed, in random order, four EQI contractions for knee extensions and flexions, respectively. EQI contractions were isotonically loaded to 70% of concentric (60°·s^-1) maximal voluntary contraction. Rest between repetitions was set at three minutes, while four minutes separated each muscle group. Peak torque, mean torque, and optimal angle were evaluated pre- and post-bouts. Inter-repetition contraction time and angular velocity were also assessed.</p><p><strong>Results: </strong>Average torque was 160.9 ± 44.2 and 71.5 ± 23.2 Nm for the extensors and flexors. Peak and mean torque significantly decreased for both extensors (p < 0.001, d = 0.70-0.71) and flexors (p ≤ 0.022, d = 0.36) after EQI contractions, respectively. However, the optimal angle increased for extensors (p < 0.001, d = 1.00) but not flexors (p = 0.811, d = 0.06). During EQI contractions, knee flexors exhibited greater intra-repetition velocity than extensors (p = 0.002; η² = 0.50). Decreases in inter-repetition time and range of motion were more consistent for the extensors.</p><p><strong>Conclusions: </strong>Distinct responses exist when comparing EQI contractions of the knee extensors and flexors, particularly their effect on peak torque angles. These findings suggest knee flexors may require lower relative intensities to align more closely with extensor EQI contractions.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141491433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex differences in laterality of motor unit firing behavior of the first dorsal interosseous muscle in strength-matched healthy young males and females.","authors":"Yuichi Nishikawa, Kohei Watanabe, Aleš Holobar, Ryoka Kitamura, Noriaki Maeda, Allison S Hyngstrom","doi":"10.1007/s00421-024-05420-7","DOIUrl":"10.1007/s00421-024-05420-7","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to compare laterality in motor unit firing behavior between females and males.</p><p><strong>Methods: </strong>Twenty-seven subjects (14 females) were recruited for this study. The participants performed ramp up and hold isometric index finger abduction at 10, 30, and 60% of their maximum voluntary contraction (MVC). High-density surface electromyography (HD-sEMG) signals were recorded in the first dorsal interosseous (FDI) muscle and decomposed into individual motor unit (MU) firing behavior using a convolution blind source separation method.</p><p><strong>Results: </strong>In total, 769 MUs were detected (females, n = 318 and males, n = 451). Females had a significantly higher discharge rate than males at each relative torque level (10%: male dominant hand, 13.4 ± 2.7 pps vs. female dominant hand, 16.3 ± 3.4 pps; 30%: male dominant hand, 16.1 ± 3.9 pps vs. female dominant hand, 20.0 ± 5.0 pps; and 60%: male dominant hand, 19.3 ± 3.8 vs. female dominant hand, 25.3 ± 4.8 pps; p < 0.0001). The recruitment threshold was also significantly higher in females than in males at 30 and 60% MVC. Furthermore, males exhibited asymmetrical discharge rates at 30 and 60% MVC and recruitment thresholds at 30 and 60% MVC, whereas no asymmetry was observed in females.</p><p><strong>Conclusion: </strong>In the FDI muscle, compared to males, females exhibited different neuromuscular strategies with higher discharge rates and recruitment thresholds and no asymmetrical MU firing behavior. Notably, the findings that sex differences in neuromuscular activity also occur in healthy individuals provide important information for understanding the pathogenesis of various diseases.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11199256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139746467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of bovine whey protein on exercise-induced gut permeability in healthy adults: a randomised controlled trial.","authors":"Dulantha Ulluwishewa, Grayson Nicholls, Harold Henderson, Daniel Bernstein, Karl Fraser, Matthew P G Barnett, Matthew J Barnes","doi":"10.1007/s00421-024-05423-4","DOIUrl":"10.1007/s00421-024-05423-4","url":null,"abstract":"<p><strong>Purpose: </strong>Intestinal permeability is a critical component of gut barrier function. Barrier dysfunction can be triggered by certain stressors such as exercise, and if left unmanaged can lead to local and systemic disorders. The aim of this study was to investigate the effects of a specific whey protein fraction in alleviating exercise-induced gut permeability as assessed by recovery of lactulose/rhamnose (L/R) and lactulose/mannitol (L/M) urinary probes.</p><p><strong>Methods: </strong>Eight males and eight females (aged 18-50) completed two arms of a double-blind, placebo-controlled, crossover study. For each arm participants performed two baseline intestinal permeability assessments, following which they consumed the treatment (2 g/day of milk powder containing 200 mg of whey protein) or placebo (2 g/day of milk powder) for 14 days, before performing a post-exercise permeability assessment. The exercise protocol involved a 20-min run at 80% of maximal oxygen uptake on a 1% incline.</p><p><strong>Results: </strong>Mixed model analysis revealed an increase in L/R (23%; P < 0.001) and L/M (20%; P < 0.01) recovery following exercise. However, there was no treatment or treatment × exercise effect.</p><p><strong>Conclusion: </strong>The exercise protocol utilised in our study induces gut permeability. However, consuming whey protein, at the dose and timing prescribed, is not able to mitigate this effect.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11199293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139930632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of curcumin supplementation on exercise performance and muscle damage after a soccer match: a double-blind placebo-controlled cross-over study.","authors":"Yoko Tanabe, Emi Kondo, Hiroyuki Sagayama, Kazuhiro Shimizu, Mikinobu Yasumatsu, Daisuke Nakamura, Naoto Fujii, Hideyuki Takahashi","doi":"10.1007/s00421-024-05429-y","DOIUrl":"10.1007/s00421-024-05429-y","url":null,"abstract":"<p><strong>Purpose: </strong>Curcumin ingestion can mitigate muscle damage, soreness, and inflammation following a laboratory-based eccentric exercise. Similar effects were observed in recent field-based studies wherein responses were evaluated after a soccer match. However, various potential confounding factors, such as matching opponent skill levels and daily training conditions, may have influenced the outcomes. In the present study, we investigated whether curcumin intake ameliorates changes in muscle damage markers following a soccer match while controlling for the potential confounding factors.</p><p><strong>Methods: </strong>Fifteen collegiate athletes were tested in a randomized, double-blind, cross-over manner. They were recruited from the same college soccer team and thus followed the same daily training regimen and competition levels. Furthermore, athletes positioning during matches were counterbalanced. They consumed either 180 mg/day of curcumin or a placebo starting 1 h before the match and continuing for 2 days after a match (two 45-min plays and a 15-min half-time). Muscle soreness, jump performance (including countermovement jump and rebound jump index), and inflammatory and muscle damage markers (high-sensitive C-reactive protein, serum creatine kinase activity, and urinary N-terminal fragment of titin concentration) were evaluated before and after the match. The washout period between matches was set at 1 week.</p><p><strong>Results: </strong>After the match, all markers showed similarity between the placebo and curcumin conditions (all P > 0.208).</p><p><strong>Conclusion: </strong>These findings indicate that ingesting 180 mg/day of curcumin may not expedite recovery from muscle damage elicited by soccer matches in collegiate soccer players.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Substrate utilization and durability during prolonged intermittent exercise in elite road cyclists.","authors":"Niels Ørtenblad, Magnus Zachariassen, Joachim Nielsen, Kasper Degn Gejl","doi":"10.1007/s00421-024-05479-2","DOIUrl":"10.1007/s00421-024-05479-2","url":null,"abstract":"","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11199240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140876228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemodynamic and neuromuscular basis of reduced exercise capacity in patients with end-stage renal disease.","authors":"Amal Machfer, Sémah Tagougui, Firas Zghal, Hayfa Ben Haj Hassen, Nadia Fekih, Hassen Ibn Hadj Amor, Hamdi Chtourou, Mohamed Amine Bouzid","doi":"10.1007/s00421-024-05427-0","DOIUrl":"10.1007/s00421-024-05427-0","url":null,"abstract":"<p><strong>Purpose: </strong>The present study aimed to characterize the exercise-induced neuromuscular fatigue and its possible links with cerebral and muscular oxygen supply and utilization to provide mechanistic insights into the reduced exercise capacity characterizing patients with end-stage renal disease (ESRD).</p><p><strong>Methods: </strong>Thirteen patients with ESRD and thirteen healthy males (CTR group) performed a constant-force sustained isometric contraction at 50% of their maximal voluntary isometric contraction (MVC) until exhaustion. Quadriceps muscle activation during exercise was estimated from vastus lateralis, vastus medialis, and rectus femoris EMG. Central and peripheral fatigue were quantified via changes in pre- to postexercise quadriceps voluntary activation (ΔVA) and quadriceps twitch force (ΔQ_tw,pot) evoked by supramaximal electrical stimulation, respectively. To assess cerebral and muscular oxygenation, throughout exercise, near-infrared spectroscopy allowed investigation of changes in oxyhemoglobin (∆O₂Hb), deoxyhemoglobin (∆HHb), and total hemoglobin (∆THb) in the prefrontal cortex and in the vastus lateralis muscle.</p><p><strong>Results: </strong>ESRD patients demonstrated lower exercise time to exhaustion than that of CTR (88.8 ± 15.3 s and 119.9 ± 14.6 s, respectively, P < 0.01). Following the exercise, MVC, Q_tw,pot, and VA reduction were similar between the groups (P > 0.05). There was no significant difference in muscle oxygenation (∆O₂Hb) between the two groups (P > 0.05). Cerebral and muscular blood volume (∆THb) and oxygen extraction (∆HHb) were significantly blunted in the ESRD group (P < 0.05). A significant positive correlation was observed between time to exhaustion and cerebral blood volume (∆THb) in both groups (r² = 0.64, P < 0.01).</p><p><strong>Conclusions: </strong>These findings support cerebral hypoperfusion as a factor contributing to the reduction in exercise capacity characterizing ESRD patients.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139905412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methodological considerations on near-infrared spectroscopy derived muscle oxidative capacity.","authors":"Letizia Rasica, Erin Calaine Inglis, Raffaele Mazzolari, Danilo Iannetta, Juan M Murias","doi":"10.1007/s00421-024-05421-6","DOIUrl":"10.1007/s00421-024-05421-6","url":null,"abstract":"<p><strong>Purpose: </strong>Different strategies for near-infrared spectroscopy (NIRS)-derived muscle oxidative capacity assessment have been reported. This study compared and evaluated (I) approaches for averaging trials; (II) NIRS signals and blood volume correction equations; (III) the assessment of vastus lateralis (VL) and tibialis anterior (TA) muscles in two fitness levels groups.</p><p><strong>Methods: </strong>Thirty-six participants [18 chronically trained (CT: 14 males, 4 females) and 18 untrained (UT: 10 males, 8 females)] participated in this study. Two trials of twenty transient arterial occlusions were performed for NIRS-derived muscle oxidative capacity assessment. Muscle oxygen consumption ( <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂m) was estimated from deoxygenated hemoglobin (HHb), corrected for blood volume changes following Ryan (HHbR) and Beever (HHbB) equations, and from oxygen saturation (StO₂) in VL and TA.</p><p><strong>Results: </strong>Superimposing or averaging <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O₂m or averaging the rate constants (k) from the two trials resulted in equivalent k values [two one-sided tests (TOST) procedure with 5% equivalence margin-P < 0.001]. Whereas HHbR (2.35 ± 0.61 min^-1) and HHbB (2.34 ± 0.58 min^-1) derived k were equivalent (P < 0.001), StO₂ derived k (2.81 ± 0.92 min^-1) was greater (P < 0.001) than both. k values were greater in CT vs UT in both muscles (VL: + 0.68 min^-1, P = 0.002; TA: + 0.43 min^-1, P = 0.01).</p><p><strong>Conclusion: </strong>Different approaches for averaging trials lead to similar k. HHb and StO₂ signals provided different k, although different blood volume corrections did not impact k. Group differences in k were detected in both muscles.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11199286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139944042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}