European Journal of Applied Physiology最新文献

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The impact of pole use on vertical cost of transport and foot force during uphill treadmill walking before and after a simulated trail running competition. 在模拟越野跑比赛前后,使用杆对上坡跑步机行走过程中垂直运输成本和足力的影响。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2025-07-07 DOI: 10.1007/s00421-025-05881-4
Nicola Giovanelli, Lara Mari, Barbara Pellegrini, Lorenzo Bortolan, Mattia d'Alleva, Federico Schena, Stefano Lazzer
{"title":"The impact of pole use on vertical cost of transport and foot force during uphill treadmill walking before and after a simulated trail running competition.","authors":"Nicola Giovanelli, Lara Mari, Barbara Pellegrini, Lorenzo Bortolan, Mattia d'Alleva, Federico Schena, Stefano Lazzer","doi":"10.1007/s00421-025-05881-4","DOIUrl":"https://doi.org/10.1007/s00421-025-05881-4","url":null,"abstract":"<p><strong>Purpose: </strong>Trail running poles are widely used among trail runners but their effects on cost of transport and biomechanics under fatigued conditions remains understudied. This study aimed to evaluate the effects of pole use on the walking vertical cost of transport (CoT<sub>vert</sub>) and foot force (FF) before and after a simulated trail running competition (STRC).</p><p><strong>Methods: </strong>Sixteen trail runners ( <math> <msub> <mrow><mover><mtext>V</mtext> <mo>˙</mo></mover> <mtext>O</mtext></mrow> <mn>2</mn></msub> </math> : 61.0 ± 8.3 ml/kg/min; ITRA performance index: 634 ± 107 points) performed walking trials with (PW) and without poles (CW) on an incline treadmill (18.6 degrees) before (PRE) and after (POST) a STRC. The course covered 31.2 km with 2086 m of elevation gain and was completed under race-simulated conditions. CoT<sub>vert</sub> and FF were measured using instrumented insoles, and axial pole force was recorded during PW.</p><p><strong>Results: </strong>The STRC was completed in 4:25:33 ± 0:39:51 (hh:mm:ss) at an average heart rate (HR) of 81.4 ± 3.8% of HRmax. Walking CoT<sub>vert</sub> showed significant time and condition effects, with higher values without poles at POST (+ 2.50 ± 2.62%, p = 0.0183). Rating of perceived exertion (RPE) was lower with poles at both PRE and POST (p = 0.0022 and p = 0.0187, respectively). FF was significantly lower with poles at PRE (p = 0.0140) and POST (p < 0.0001). Poling force decreased at POST compared to PRE (p = 0.0026).</p><p><strong>Conclusions: </strong>The main findings are that (1) CoT<sub>vert</sub> increases after STRC; (2) walking CoT<sub>vert</sub> and FF are lower with pole use and (3) upper limb force decreases at POST. These results support the use of poles in long-lasting events to reduce CoT, redistribute workload and possibly mitigate the fatigue effects.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Countermovement jump performance after metabolically, but not mechanically demanding exercise: limited sensitivity to prolonged low-frequency force depression. 代谢性运动后的反动作跳跃表现,但不是机械要求高的运动:对长时间低频力抑制的敏感性有限。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2025-07-06 DOI: 10.1007/s00421-025-05882-3
Owen R Lindsay, Jared R Fletcher
{"title":"Countermovement jump performance after metabolically, but not mechanically demanding exercise: limited sensitivity to prolonged low-frequency force depression.","authors":"Owen R Lindsay, Jared R Fletcher","doi":"10.1007/s00421-025-05882-3","DOIUrl":"https://doi.org/10.1007/s00421-025-05882-3","url":null,"abstract":"<p><strong>Rationale: </strong>Previous studies indicate that countermovement jump (CMJ) parameters may reflect neuromuscular fatigue following exhaustive exercise. However, changes in CMJ performance in response to non-muscle damaging exercise, and its relation to prolonged low-frequency force depression (PLFFD) is yet unknown.</p><p><strong>Purpose: </strong>This study aimed to evaluate the relationship between PLFFD and CMJ test parameters following exhaustive cycling exercise to task failure.</p><p><strong>Methods: </strong>A sample of 11 recreationally active adults completed an incremental cycling protocol to task failure. CMJ performance, low-frequency (10 Hz) force, and maximal voluntary contraction (MVC) force output were assessed at baseline (pre-exercise), immediately after task failure (0 min), and at 8 min, 15 min, 60 min, 24 h, and 48 h post-task failure. PLFFD was assessed as the ratio of 10 Hz to MVC force.</p><p><strong>Results: </strong>Compared to baseline, PLFFD was larger from 0 min (7.4%) to 60-min (6.7%, p < 0.002). In contrast, no substantial changes in CMJ parameters were observed, except for a reduced concentric impulse (ConImp) lasting 8 min post-exercise.</p><p><strong>Conclusion: </strong>The results show that CMJ parameters remain unchanged following non-eccentrically loaded exhaustive exercise, while PLFFD is significantly higher for up to 60 min post-exercise. This raises questions about the utility of CMJ as a fatigue assessment tool in athletic populations. This suggests that CMJ testing may not effectively detect the presence of PLFFD following non-muscle damaging exercise and future research should explore alternative measures for monitoring neuromuscular fatigue in training contexts.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The interaction between exercise and sleep with heart rate variability: cross-sectional study. 运动和睡眠与心率变异性的相互作用:横断面研究。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2025-07-05 DOI: 10.1007/s00421-025-05887-y
Taylor Fein, T Muhammad, Soomi Lee
{"title":"The interaction between exercise and sleep with heart rate variability: cross-sectional study.","authors":"Taylor Fein, T Muhammad, Soomi Lee","doi":"10.1007/s00421-025-05887-y","DOIUrl":"https://doi.org/10.1007/s00421-025-05887-y","url":null,"abstract":"<p><strong>Purpose: </strong>To examine whether the interaction between exercise intensity and sleep duration/quality is associated with heart rate variability (HRV).</p><p><strong>Methods: </strong>A sample of 391 adults (M<sub>age</sub> = 57 years) from the Midlife in the United States Biomarker study 2004-2009 provided sleep actigraphy, electrocardiogram (ECG) HRV measurements, completed the Pittsburgh Sleep Quality Index (PSQI), and answered questions on exercise habits. Participants were grouped as short (< 6 h) or non-short sleepers (≥ 6 h), poor (> 5 PSQI global score), or good sleepers (< 6 PSQI global score), and exercise was divided into vigorous (VPA) and moderate (MPA) intensities. Based on CDC guidelines, VPA was classified into adequate (≥ 75 min/week) and inadequate (< 75 min/week) groups. For MPA, adequate (≥ 150 min/week) and inadequate (< 150 min/week) groups. Linear models, adjusted for sociodemographic and health-related covariates, examined the interaction between sleep duration/quality and exercise on HRV.</p><p><strong>Results: </strong>Inadequate VPA was associated with lower HRV, HF-HRV (B = - 0.25, SE = 0.09, p = 0.007), and RMSSD (B = - 0.15, SE = 0.05, p = 0.0009). MPA showed no significant main associations with HRV. Sleep duration/quality did not show direct associations with HRV; however, interactions were found with sleep duration. Among short sleepers, inadequate VPA was associated with lower HF-HRV (B = - 0.62, SE = 0.25, p = 0.01) and inadequate MPA was associated with lower RMSSD (B = - 0.26, SE = 0.10, p = 0.01) compared to adequate exercise. Among non-short sleepers, there were no significant differences in HRV between exercise groups.</p><p><strong>Conclusion: </strong>These findings suggest that short sleep and inadequate exercise may interact to lower HRV.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is intensity the most important factor in determining the amount of prior work accumulated that affects cyclists' acute durability? A systematic review. 强度是决定影响骑车者急性耐力的累积工作量的最重要因素吗?系统回顾。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2025-07-04 DOI: 10.1007/s00421-025-05885-0
Jose Luis Sánchez-Jiménez, Jose-Antonio Salas-Montoro, Manuel Mateo-March, Jose Ignacio Priego-Quesada, Mikel Zabala, Juan-José Pérez-Díaz
{"title":"Is intensity the most important factor in determining the amount of prior work accumulated that affects cyclists' acute durability? A systematic review.","authors":"Jose Luis Sánchez-Jiménez, Jose-Antonio Salas-Montoro, Manuel Mateo-March, Jose Ignacio Priego-Quesada, Mikel Zabala, Juan-José Pérez-Díaz","doi":"10.1007/s00421-025-05885-0","DOIUrl":"https://doi.org/10.1007/s00421-025-05885-0","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to determine how exercise intensity influences the amount of work required to induce changes in cyclists' acute durability and to evaluate the suitability of using kilojoules (kJ) as a metric for fatigue monitoring.</p><p><strong>Methods: </strong>A systematic review was conducted following PRISMA guidelines. Web of Science, Medline, and Scopus were searched for studies assessing the relationship or effect between prior accumulated work and performance reductions in cyclists. Inclusion criteria required studies to measure power output after fatigue induced within a single session, with prior work quantified in kJ or other training load metrics.</p><p><strong>Results: </strong>Twenty-one studies were included in the systematic review. The primary finding was that high-intensity efforts (e.g., above critical power) led to greater power output reductions with lower accumulated work compared to low-to-moderate intensity efforts. Across studies, power output declines of 10-20% were observed after 2.5-15 kJ kg⁻<sup>1</sup> of prior high-intensity work, whereas similar or greater work volumes at lower intensities resulted in smaller performance decrements. While kJ was the most commonly used fatigue metric, it does not account for intensity, limiting its accuracy in durability assessments.</p><p><strong>Conclusions: </strong>Exercise intensity plays a crucial role in determining durability-related performance declines. The exclusive use of kJ as a fatigue metric may be insufficient, and alternative approaches incorporating intensity are needed. These findings have implications for training prescription and race strategies, emphasizing the need for intensity-specific workload quantification.</p><p><strong>Registration: </strong>OSF project no.: osf.io/kcg53.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144559582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detrended fluctuation analysis of heart rate variability during exercise: Time to reconsider the theoretical and methodological background. Comment on: Cassirame et al.`s (2025) Detrended fluctuation analysis to determine physiologic thresholds, investigation and evidence from incremental cycling test. Eur J Appl Physiol 125:523-533. 运动期间心率变异性的无趋势波动分析:是时候重新考虑理论和方法背景了。评论:cassiame等人(2025)的无趋势波动分析,以确定生理阈值,从增量循环试验的调查和证据。[J] .中国生物医学工程学报,25(5):523-533。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2025-07-04 DOI: 10.1007/s00421-025-05859-2
Olaf Hoos, Thomas Gronwald
{"title":"Detrended fluctuation analysis of heart rate variability during exercise: Time to reconsider the theoretical and methodological background. Comment on: Cassirame et al.`s (2025) Detrended fluctuation analysis to determine physiologic thresholds, investigation and evidence from incremental cycling test. Eur J Appl Physiol 125:523-533.","authors":"Olaf Hoos, Thomas Gronwald","doi":"10.1007/s00421-025-05859-2","DOIUrl":"https://doi.org/10.1007/s00421-025-05859-2","url":null,"abstract":"","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute effects of two different combined exercise modalities on executive function and circulating neurotrophic factors in young healthy adults. 两种不同的联合运动方式对年轻健康成人执行功能和循环神经营养因子的急性影响
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2025-07-03 DOI: 10.1007/s00421-025-05877-0
Yi-Hung Liao, Toby Mündel, Ying-Chu Chen, Shiow-Chwen Tsai, Kuo-Cheng Wu, Mu-Tsung Chen, Li-Chen Lee, Chih-Peng Su, Yu-Kai Chang, Chung-Yu Chen
{"title":"Acute effects of two different combined exercise modalities on executive function and circulating neurotrophic factors in young healthy adults.","authors":"Yi-Hung Liao, Toby Mündel, Ying-Chu Chen, Shiow-Chwen Tsai, Kuo-Cheng Wu, Mu-Tsung Chen, Li-Chen Lee, Chih-Peng Su, Yu-Kai Chang, Chung-Yu Chen","doi":"10.1007/s00421-025-05877-0","DOIUrl":"https://doi.org/10.1007/s00421-025-05877-0","url":null,"abstract":"<p><strong>Purposes: </strong>This study investigated the effects of two different combined exercise modalities on executive function in healthy adults and observed the associations of potential biomarkers (i.e., brain-derived neurotrophic factor, BDNF; human growth hormone, HGH; insulin-like growth factor-1, IGF-1; and cortisol) on cognitive performance.</p><p><strong>Methods: </strong>Twelve young healthy male adults were recruited and assigned to the following three experimental interventions in a randomized crossover manner: sitting control (SC), resistance exercise plus continuous aerobic exercise (RA) and resistance exercise plus intermittent aerobic exercise (RI). Stroop Color and Word Test (SCWT) and blood collection were conducted before and immediately after each intervention.</p><p><strong>Results: </strong>The results showed that both acute combined exercise trials significantly reduced SCWT-incongruent response time compared to the SC trial (RA: p = .015, RI: p = .014). The serum BDNF and HGH levels were significantly increased in both RA (BDNF: p < .0001, HGH: p = .004) and RI (BDNF: p = .013, HGH: p = .007) trials, and the serum IGF-1 level was significantly increased in the RI trial (p = .008). The changes in SCWT-incongruent response time were significantly associated with the changes in blood lactate (r = - 0.622, p < .0001) and RPE (r = - 0.364, p = .029) following the interventions.</p><p><strong>Conclusion: </strong>Our findings indicate the beneficial effects of two different combined exercise modalities on executive function in these young healthy males that could be related to an increase in brain energy supply and arousal status.</p><p><strong>Irb registration number: </strong>IRB-2021-011.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is maximal oxygen consumption an appropriate metric for metabolic health? 最大耗氧量是衡量代谢健康的合适指标吗?
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2025-07-03 DOI: 10.1007/s00421-025-05875-2
Dale I Lovell, Max Stuelcken, Alexander Eagles
{"title":"Is maximal oxygen consumption an appropriate metric for metabolic health?","authors":"Dale I Lovell, Max Stuelcken, Alexander Eagles","doi":"10.1007/s00421-025-05875-2","DOIUrl":"https://doi.org/10.1007/s00421-025-05875-2","url":null,"abstract":"<p><p>Cardiorespiratory fitness (CRF), assessed by maximal oxygen consumption ( <math><mover><mtext>V</mtext> <mo>˙</mo></mover> </math> O<sub>2</sub> max) testing, is a strong predictor of chronic disease and all-cause mortality. However, recent evidence suggests that <math><mover><mtext>V</mtext> <mo>˙</mo></mover> </math> O<sub>2</sub> max may lack specificity and sensitivity in assessing metabolic health, particularly mitochondrial function, which is associated with metabolic diseases such as type 2 diabetes, insulin resistance, and metabolic syndrome. While aerobic training leads to improvements in mitochondrial function, studies have found a disparity between <math><mover><mtext>V</mtext> <mo>˙</mo></mover> </math> O<sub>2</sub> max and mitochondrial content, with some individuals showing increases in mitochondrial oxidative capacity without changes in <math><mover><mtext>V</mtext> <mo>˙</mo></mover> </math> O<sub>2</sub> max. Furthermore, the criteria used to determine <math><mover><mtext>V</mtext> <mo>˙</mo></mover> </math> O<sub>2</sub> max, such as the plateau in oxygen consumption, may not be achieved by all individuals, leading to inaccurate assessments. Technological advances in metabolomics and lipidomics may provide insights into metabolic health, but their cost and practicality for routine use in clinical settings remain a challenge. Alternatively, indirect calorimetry during submaximal exercise has shown promise as a non-invasive marker of mitochondrial function and metabolic flexibility. However, further research is needed to establish appropriate protocols and analyses for various populations.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144559594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kinetics of cell-free DNA in response to exogenous and exertional heating in healthy young men. 健康年轻男性对外源性和运动性加热反应的无细胞DNA动力学。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2025-07-03 DOI: 10.1007/s00421-025-05861-8
Ema Juškevičiūtė, Elmo W I Neuberger, Nerijus Eimantas, Katharina Hoeter, Yu-Kai Chang, Perikles Simon, Marius Brazaitis
{"title":"Kinetics of cell-free DNA in response to exogenous and exertional heating in healthy young men.","authors":"Ema Juškevičiūtė, Elmo W I Neuberger, Nerijus Eimantas, Katharina Hoeter, Yu-Kai Chang, Perikles Simon, Marius Brazaitis","doi":"10.1007/s00421-025-05861-8","DOIUrl":"https://doi.org/10.1007/s00421-025-05861-8","url":null,"abstract":"<p><strong>Purpose: </strong>Circulating cell-free DNA (cfDNA) is recognized as a relevant biomarker for monitoring the effects of various physiological and pathophysiological factors. To identify the effect of body temperature, we investigated the kinetics of cfDNA in response to two forms of heating.</p><p><strong>Methods: </strong>In a randomized crossover design, twelve healthy young males cycled at 60% of their maximum oxygen uptake (VO<sub>2max</sub>) (exertional heating) and conducted lower-body immersion in hot water (43-44°C) (exogenous heating) until their rectal temperature (T<sub>re</sub>) reached 39°C. EDTA blood samples were collected at each time point T<sub>re</sub> increased and decreased by 0.5°C, to determine the concentrations of cfDNA, epinephrine (Epi), norepinephrine (NE), prolactin (PRL), as well as subjective sensation, and heart rate.</p><p><strong>Results: </strong>Linear mixed model analyses revealed a strong significant interaction effect for cfDNA (T<sub>re</sub> × heating modality, F (6, 135.95) = 7.51, P < 0.001), with a significant 1.76-fold increase of cfDNA in response to exogenous heating and a 5.72-fold increase in response to exertional heating (P < 0.05). Significant interaction effects were detected for NE (F (6, 109.80) = 8.0683, P < 0.001), and PRL (F (6, 120.92) = 2.2746, P = 0.041), but not Epi. Repeated measures correlation (r<sub>rm</sub>) showed strong correlations between cfDNA and core temperature in exertional heating (r<sub>rm</sub> = 0.89), as well as exogenous heating (r<sub>rm</sub> = 0.75).</p><p><strong>Conclusion: </strong>Our findings demonstrate that an increase in rectal temperature induces physiological stress, which triggers the release of cfDNA, however, at a significantly lower level than exertional heating, suggesting that mechanical stress has a greater influence on the release.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sustained sitting attenuates cutaneous reactive hyperemia while improving venoarteriolar reflex, and alternating ambient exposure to cool and heat does not modulate these responses. 持续坐着可减轻皮肤反应性充血,同时改善静脉小动脉反射,而交替暴露于冷热环境中不会调节这些反应。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2025-07-02 DOI: 10.1007/s00421-025-05870-7
Kaname Tagawa, Yudai Tomita, Takeshi Nishiyasu, Naoto Fujii
{"title":"Sustained sitting attenuates cutaneous reactive hyperemia while improving venoarteriolar reflex, and alternating ambient exposure to cool and heat does not modulate these responses.","authors":"Kaname Tagawa, Yudai Tomita, Takeshi Nishiyasu, Naoto Fujii","doi":"10.1007/s00421-025-05870-7","DOIUrl":"https://doi.org/10.1007/s00421-025-05870-7","url":null,"abstract":"<p><strong>Purpose: </strong>Impaired skin microcirculation is considered an early marker of cardiovascular disease. Elevated sedentary behavior can impair vascular function and increase cardiovascular risk. However, whether prolonged sitting induces skin microvascular dysfunction remains uncertain, and no effective intervention has been identified.</p><p><strong>Methods: </strong>Twelve young adults (six women) sat for 120 min wherein they were exposed to 18 °C for ≥ 5 min, followed by exposure to 35 °C for ≥ 5 min, with this sequence repeated twice. Temperature transitions lasted ≥ 20 min. On separate day, during the control trial, participants were exposed to thermoneutral ambient temperature of 25 °C for 120 min. Cutaneous blood flow was continuously recorded throughout the experiment. Post-occlusive reactive hyperemia (PORH) was assessed by measuring increases in cutaneous blood flow following arterial occlusion. Venoarteriolar reflex (VAR) was elicited by venous occlusion. These occlusions were conducted at the upper arm pre- and post-intervention.</p><p><strong>Results: </strong>Cutaneous blood flow gradually decreased in the control trial, whereas it declined during cool exposure and remained unchanged from pre-exposure levels during heat exposure. Baseline cutaneous blood flow was similar between the two trials at pre- and post-intervention. PORH decreased (time effect: p = 0.047), whereas VAR (%baseline) improved (time effect: p = 0.018) following 120 min sitting in both trials, with no between-trial differences [interaction: p = 0.990 (PORH) and 0.869 (VAR)].</p><p><strong>Conclusion: </strong>(1) Prolonged sitting decreased cutaneous PORH, while unexpectedly improving VAR, and (2) these responses were not modulated by cutaneous blood flow fluctuations induced by alternate ambient exposure to cool and heat.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of simultaneous aerobic and inspiratory muscle training on diaphragm function, respiratory muscle strength, endurance, and fatigue index: randomized-controlled trial. 同时有氧和吸气肌训练对膈肌功能、呼吸肌力量、耐力和疲劳指数的影响:随机对照试验。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2025-07-02 DOI: 10.1007/s00421-025-05868-1
Zeliha Çelik, Nevin A Güzel, Seriyye Allahverdiyeva, Halit Nahit Şendur, Mahi Nur Cerit
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