European journal of orthodontics最新文献

{"title":"Objective adherence to oral appliance therapy in patients with obstructive sleep apnea: a one-year longitudinal analysis.","authors":"Yanlong Chen, Benjamin T Pliska, Bingshuang Zou, Fernanda R Almeida","doi":"10.1093/ejo/cjaf037","DOIUrl":"10.1093/ejo/cjaf037","url":null,"abstract":"<p><strong>Introduction: </strong>Oral appliance (OA) therapy is widely used as an alternative to continuous positive airway pressure (CPAP) therapy for treating obstructive sleep apnea (OSA). Traditionally, OA adherence has been assessed through subjective self-reports before, but the availability of objective adherence sensors now allows for more accurate monitoring. This study aimed to analyze one-year objective adherence data to identify adherence patterns over time and factors influencing adherence to OA therapy.</p><p><strong>Materials and methods: </strong>Fifty-five OSA patients were recruited from a cohort study and underwent clinical follow-ups at baseline, 1, 6 and 12 months. Patients were treated with custom-made, titratable OAs, and adherence was objectively collected using embedded sensors. Adherence data were analyzed using both intention-to-treat (ITT) and per-protocol (PP) approaches. Statistical methods, including comparative analyses, logistic regression models, and multivariate linear regression were performed to identify predictors of adherence.</p><p><strong>Results: </strong>Twenty-one patients dropped out before the 12-month follow-up, leaving 34 completed the entire study. At the 1-month follow-up, 80.0% of patients were classified as adherent, with a mean wearing time of 5.98 ± 2.38 hours per night. By 6 months, adherence decreased to 67.3%, with a mean wearing time of 5.69 ± 2.08 hours per night. Several significant predictors of adherence were identified, including larger baseline overjet, younger age, and marital status.</p><p><strong>Conclusions: </strong>OA adherence declined significantly within the first 6 months but stabilized between 6 and 12 months. Key baseline factors, such as larger overjet, younger age, and being married or partnered are predictors of better adherence, while psychological Comorbidities are associated with lower adherence.</p>","PeriodicalId":11989,"journal":{"name":"European journal of orthodontics","volume":"47 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12187995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reporting and interpretation of subgroup analyses in orthodontic meta-analysis; a meta-epidemiological study.","authors":"Lorna Hirst, Iro Ntaga, Jadbinder Seehra, Dimitrios Mavridis, Nikolaos Pandis","doi":"10.1093/ejo/cjaf053","DOIUrl":"10.1093/ejo/cjaf053","url":null,"abstract":"<p><strong>Background/objectives: </strong>In systematic reviews (SRs) with a meta-analysis, a subgroup analysis can be utilised to explore heterogeneity of treatment effects across patient characteristics and assess how patient characteristics, types of intervention, or trial characteristics modify the treatment effect. The aim of this meta-epidemiological study was to investigate the reporting and interpretation of subgroup analyses in the orthodontic literature.</p><p><strong>Methodology: </strong>SRs published between 1st January 2017 - 30th June 2024 in five orthodontic journals and the Cochrane Database of Systematic Reviews (CDSR) were hand searched from journal websites. We assessed the presence of testing for subgroup differences (interaction test) and the interpretation and reporting of subgroup analysis limitations were also reviewed. Descriptive statistics of the SR characteristics and univariable cross-tabulation to detect associations between journal type and variables affecting interpretation of subgroup analyses were undertaken. On an exploratory basis, exact logistic regression was used to examine the effect of publication year on the correct interpretation of subgroup results.</p><p><strong>Results: </strong>Five thousand one-hundred and one (5101) articles were screened, 298 SRs were identified of which 70 met the inclusion criteria. In the subgroup analysis, interpretation of the p-value was undertaken in just over half of cases (n = 40, 57.1%). Only 32.9% (n = 23) of subgroup analyses were deemed correctly interpretated. Most commonly, no subgroup limitations were reported by the authors (n = 48, 68.6%) even when such limitations existed. There was no association between year of publication and correct interpretation of subgroup analyses (OR:0.93, 95% CI: 0.70, 1.22, p = 0.62).</p><p><strong>Conclusion: </strong>There appears to be a lack of awareness of how to correctly interpret subgroup analyses from forest plots. Only a third of orthodontic subgroup analyses assessed in this study were correctly interpreted. Misinterpretation of the effect of covariates (e.g. patient characteristics) on the effect of a treatment intervention could potentially have a negative impact on patient healthcare decisions. Recommendations to improve the interpretation of subgroup analyses are proposed.</p>","PeriodicalId":11989,"journal":{"name":"European journal of orthodontics","volume":"47 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144658770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative microscopic analysis of plastic dispersion from 3D-printed and thermoformed orthodontic aligners.","authors":"Piero Antonio Zecca, Marina Borgese, Mario Raspanti, Francesca Zara, Rosamaria Fastuca, Marco Serafin, Alberto Caprioglio","doi":"10.1093/ejo/cjaf014","DOIUrl":"10.1093/ejo/cjaf014","url":null,"abstract":"<p><strong>Aim: </strong>To compare directly printed aligners (DPA) and thermoformed aligners (TFA), evaluating the potential release and dispersion of microplastic (MP) and nanoplastic (NP) particles under simulated oral conditions.</p><p><strong>Materials and methods: </strong>DPA samples (Graphy Tera Harz TC-85-DAC resin) and TFA samples (Invisalign® SmartTrack) were subjected to rubs in an ultrapure water bath. The liquid was collected post-friction and analyzed for MPs and NPs using various techniques: optical microscopy (OM), transmission electron microscopy (TEM), and atomic force microscopy (AFM). Also, plastic residues were quantified by weighing after drying within a laminar flow hood. Microscopic image analyses comprised the quantification of the average size of MPs and NPs, their concentration by TEM, and the roughness analysis by AFM.</p><p><strong>Results: </strong>The masses of MPs and NPs separated after rubbing were 0.001 g/200 µl and 0.004 g/200 µl for TFA and DPA samples, respectively. TEM analysis confirmed that DPA samples had larger (203.08 ± 2651.65 μm²) and more numerous particles compared to TFA (0.23 ± 27.53 μm²), even though it was not possible to distinguish the MPs and NPs due to clustering of the plastic residuals. AFM analysis indicated a bigger root mean square grain size for TFA than DPA; similarly, the mean roughness was lesser in the DPA sample than TFA one.</p><p><strong>Conclusions: </strong>DPA generated larger and more numerous plastic particles compared to TFA, though grain-size characterization was challenging due to particle aggregation. This suggests that the manufacturing process and materials used in DPA could impact the creation of MPs and NPs during simulated mastication, highlighting a potential area for process optimization.</p>","PeriodicalId":11989,"journal":{"name":"European journal of orthodontics","volume":"47 3","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12284233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of orthodontic treatment with fixed appliances on the development of gingival recession. A prospective controlled study.","authors":"Dimitrios Kloukos, George Koukos, Nikolaos Pandis, Ioannis Doulis, Andreas Stavropoulos, Christos Katsaros","doi":"10.1093/ejo/cjaf022","DOIUrl":"10.1093/ejo/cjaf022","url":null,"abstract":"<p><strong>Objective: </strong>To assess in a prospective controlled study whether orthodontic treatment with fixed appliances results in development of gingival recession (GR), compared with an untreated group of participants.</p><p><strong>Materials & methods: </strong>The sample consisted of 40 consecutive adult orthodontic patients (Intervention group) and 40 untreated adult volunteers, that satisfied the inclusion and exclusion criteria and were selected from the same background population, as the control group. GR was measured as part of a full periodontal assessment: before treatment (T0) and 12 months after removal of the fixed appliances (T1) in the intervention group, i.e. at about 30 months from T0, and at baseline (T0) and 30 months after (T1) in the control group. A count data model was fit using the sum of recessions at T1 and as predictors: treatment, periodontal phenotype (thin/thick), side (buccal/lingual), sex, age, and number of recessions at baseline, with robust standard errors to account for the multiple within patient observations.</p><p><strong>Results: </strong>Nineteen females and 21 males in each group [mean age in years (range): intervention group 23.1 (16.8 - 43.3); control: 21.85 (18.2 - 43.9)] were analyzed. During the whole study period, the control group exhibited a modest increase in the number of recessions over time. Several patients in the intervention group exhibited a larger increase in the number of recessions than the controls. However, this was partly counteracted by a considerable amount of reduction in the number of recessions in several patients receiving treatment. The adjusted incidence for recession was 67% higher for the intervention group versus the control group (IRR = 1.67, 95% CIs: 1.05, 2.67, P = 0.03). Most recessions, though, were up to 1mm. The most affected teeth were the canines and the first premolars.</p><p><strong>Conclusions: </strong>Compared to untreated individuals, patients undergoing orthodontic treatment with fixed appliances showed a higher incidence rate of gingival recession at 1-year posttreatment, adjusted for age, periodontal phenotype, side, gender and number of recessions at baseline. However, the severity of gingival recessions was of limited extent.</p>","PeriodicalId":11989,"journal":{"name":"European journal of orthodontics","volume":"47 3","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12116418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative evaluation of salivary and plasma bisphenol-A levels in patients released from four different orthodontic appliances: ultra-performance liquid chromatography-mass spectrometry study. A non-randomized clinical trial.","authors":"Serdar Cik, Nihat Kilic, Alptug Atila","doi":"10.1093/ejo/cjaf021","DOIUrl":"https://doi.org/10.1093/ejo/cjaf021","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the amount of bisphenol-A (BPA) released from different orthodontic appliances into saliva and plasma and to compare BPA levels between orthodontic appliance groups.</p><p><strong>Methods: </strong>This non-randomized clinical trial included 78 patients, and they were divided into four groups: fixed appliance, temporary anchorage devices (TADs), removable appliance, and functional appliance groups. Saliva and plasma samples were collected before treatment/appliance wear (T0) and one day (T1), one week (T2), and one month (T3) after treatment/appliance wear. Saliva and plasma BPA levels were analysed using Ultra-performance Liquid Chromatography-Mass Spectrometry (UPLC-MS/MS). Data was analysed using analysis of variance (ANOVA) and Tukey HSD multiple comparison tests with Bonferroni correction. Correlations between saliva and plasma BPA levels at different time points were evaluated using Pearson correlation analysis.</p><p><strong>Results: </strong>BPA levels ranged from 0.07-7.28 ng/ml in saliva samples and from 0.17-12.51 ng/ml in plasma samples in all groups. Within-group comparisons showed no significant changes over time (p > 0.0125) in each group. Between-group comparisons showed significantly higher saliva BPA levels in the fixed appliance group compared to the other groups (p < 0.017), with no significant differences in plasma BPA levels between groups (p < 0.0175). Positive correlations were observed between saliva BPA measurements, whereas positive correlation was observed only between T0 and T3 plasma PBA levels.</p><p><strong>Conclusion: </strong>This research obviously demonstrated that the orthodontic appliances we investigated release BPA into the saliva. However, the BPA levels detected in both saliva and plasma are consistently within the acceptable safety limits. However, precautions should be taken to minimize BPA release during orthodontic treatment.</p>","PeriodicalId":11989,"journal":{"name":"European journal of orthodontics","volume":"47 3","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient experiences with clear aligners: a scoping review.","authors":"Hannah Chong, Joshua Peh, Tony Weir, Maurice J Meade","doi":"10.1093/ejo/cjaf017","DOIUrl":"https://doi.org/10.1093/ejo/cjaf017","url":null,"abstract":"<p><strong>Introduction: </strong>Clear aligner therapy (CAT) is an aesthetic alternative to fixed appliance therapy (FAT). An understanding of patient experiences with CAT can enable clinicians to educate patients, manage expectations, and identify potential barriers to effective treatment. A scoping review was undertaken to map and synthesise the available evidence on patient experiences with CAT.</p><p><strong>Methods: </strong>The review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) guidelines. The PubMed (MEDLINE), Embase, Scopus, Web of Science and Dentistry & Oral Sciences Source databases and grey literature were searched. Data collation and synthesis was presented in descriptive and tabular formats.</p><p><strong>Results: </strong>The initial search yielded 541 articles following removal of duplicate studies. 37 studies met the selection criteria and were scoped in the present review. The studies identified included cross-sectional, longitudinal, prospective, and randomised clinical trials reporting on patient experiences with CAT associated with Oral Health-Related Quality of Life (OHRQOL) and satisfaction. The impacts of CAT on OHRQOL with relevance to pain was the most frequently evaluated aspect, followed by speech, satisfaction, eating, anxiety, and sleep.</p><p><strong>Conclusions: </strong>CAT patients report satisfaction with the aesthetics of the appliance however can expect transient negative effects on OHRQOL, pain, anxiety, and speech after commencing treatment. Further longitudinal research using validated qualitative tools focussing on CAT is required.</p><p><strong>Registration: </strong>This review was registered in the Open Science Framework database (DOI: xx).</p>","PeriodicalId":11989,"journal":{"name":"European journal of orthodontics","volume":"47 3","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reporting of CONSORT flow diagrams for parallel group randomized controlled trials published in orthodontic journals.","authors":"Marianna Koufatzidou, Ilias Karveleas, Ioanna Mitsika, Krishna Patel, Jadbinder Seehra, Nikolaos Pandis","doi":"10.1093/ejo/cjaf019","DOIUrl":"https://doi.org/10.1093/ejo/cjaf019","url":null,"abstract":"<p><strong>Background/objectives: </strong>The inclusion of a participant flow diagram in randomized clinical trials (RCTs) is a requirement of the CONSORT guidelines. The aim of this study was to assess the reporting quality of flow diagrams of RCTs published in orthodontic journals in relation to the CONSORT Flow Diagram for Parallel Group RCTs.</p><p><strong>Materials/methods: </strong>RCTs published between January 2011 and December 2023 in five orthodontic journals were identified and trial characteristics were extracted. The reporting of the flow diagram (if included) was assessed for completeness in relation to the CONSORT flow diagram template. Descriptive statistics and cross tabulations between RCT characteristics and presence/no presence of a flow diagram were performed. On an exploratory basis, univariable associations between RCT characteristics and presence/no presence of a flow diagram were performed and univariable logistic regression to examine the effect of publication year on flow diagram reporting.</p><p><strong>Results: </strong>Three hundred and thirty-four RCTs met the inclusion criteria. The majority were published in 2021 (n = 39, 11.7%), and had 2 arms (n = 279, 83.5%). Three-hundred and seven (92.0%) RCTs were published in journals endorsing the CONSORT guidelines. Two hundred and thirty-three (69.8%) RCTs included a flow diagram and from these, 48.1% (n = 112) were fully compliant with flow diagram reporting. 121 (51.9%) omitted at least one item of the CONSORT reporting template. Significant associations between journal type, CONSORT endorsement by authors, ethical approval status, presence of a published protocol, significance of the primary outcome, involvement of a statistician, presence of conflict of interest, center type, type of analysis undertaken and the presence/ no presence of a flow diagram were present. Across the study timeframe, the odds of inclusion of RCT flow diagram increased per additional year (OR:1.47; 95%CI:1.34,1.61; p < .001).</p><p><strong>Limitations: </strong>Only five orthodontic journals.</p><p><strong>Conclusions/implications: </strong>Despite improvements over time, the inclusion and reporting of CONSORT flow diagram for parallel group RCTs in trials published in orthodontic journals requires improvement. To mitigate potential biased interpretation of trial results, journal editors should ensure a complete CONSORT flow diagram is submitted by researchers.</p>","PeriodicalId":11989,"journal":{"name":"European journal of orthodontics","volume":"47 3","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative tooth crowding analysis in occlusal intra-oral photographs using a convolutional neural network.","authors":"Gabriel Hertig, Niels van Nistelrooij, Jan Schols, Tong Xi, Shankeeth Vinayahalingam, Raphael Patcas","doi":"10.1093/ejo/cjaf025","DOIUrl":"10.1093/ejo/cjaf025","url":null,"abstract":"<p><strong>Background: </strong>Dental crowding is a primary concern in orthodontic treatment and significantly impacts therapy choices. Accurate quantification of crowding requires time-intensive cast- or scan-based measurements. The aim was to develop an automated deep-learning model capable of assessing anterior crowding and calculating the Little Irregularity Index using single occlusal intra-oral photographs.</p><p><strong>Methods: </strong>A dataset of 125 untreated individuals (100 from Zurich, Switzerland, and 25 from Nijmegen, the Netherlands) comprised of annotated intra-oral scans and corresponding intra-oral photographs were used to train a dedicated convolutional neural network (CNN). The CNN was modeled to detect teeth boundaries, contact points and contact point displacements on photographs. The model's performance to determine anterior crowding and the Little Irregularity Index score was compared to consensus measurements based on intra-oral scans in terms of intra-class correlation (ICC) and mean absolute difference (MAD).</p><p><strong>Results: </strong>The model correlated well with the consensus measurement, and proved to be reliable (ICC = 0.900) and accurate (MAD = 0.36 mm) for anterior crowding assessment and Little Irregularity Index alike (ICC = 0.930; MAD = 0.74 mm).</p><p><strong>Limitation: </strong>The model was not trained on cases with interdental spacing, and its reliability for cases with crowding severity outside the tested sample has not been established.</p><p><strong>Conclusion: </strong>The presented CNN-based model was able to quantify the crowding in the anterior segment of the lower dental arch and score the Little Irregularity Index from a single intra-oral photograph with a satisfactory reliability and accuracy. Application of this model may lead to more efficient and convenient orthodontic diagnostics.</p>","PeriodicalId":11989,"journal":{"name":"European journal of orthodontics","volume":"47 3","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of myofunctional therapy on orthodontic management and orthognathic surgery outcomes: a scoping review.","authors":"Cristine M Stefani, Adriano de Almeida de Lima, Fabiane M Stefani, Janice Y Kung, Sharon Compton, Carlos Flores-Mir","doi":"10.1093/ejo/cjaf024","DOIUrl":"https://doi.org/10.1093/ejo/cjaf024","url":null,"abstract":"<p><strong>Background: </strong>Orofacial myofunctional disorders (OMDs) are conditions or behaviors that negatively affect oral postures and functions. These behaviors can interfere with normal orofacial growth and development and related functions.</p><p><strong>Objectives: </strong>Map the available evidence regarding the effectiveness of Orofacial Myofunctional Therapy (OMT) in treating or managing OMDs associated with specific malocclusion traits or orthognathic surgery outcomes.</p><p><strong>Search methods: </strong>An experienced librarian developed a comprehensive search strategy for six databases and gray literature. The reference lists of included studies were reviewed.</p><p><strong>Selection criteria: </strong>Randomized controlled trials and non-randomized studies of intervention were included in which individuals with OMDs were treated with OMT, regardless of the healthcare setting or the professional delivering the treatment.</p><p><strong>Data collection and analysis: </strong>Two independent reviewers screened the retrieved records in two phases based on predefined eligibility criteria and extracted data. The evidence level was assessed using the Oxford Levels of Evidence.</p><p><strong>Results: </strong>Twenty-four studies were included (18 primary studies and 6 reviews). Seven studies focused on OMDs associated with malocclusion sagittal characteristics (Class I, II, or III), ten examined open-bite-related OMDs, and seven explored OMDs following orthognathic surgery. Only four studies (22%) were randomized controlled trials (RCTs); most studies lacked proper randomization procedures, did not report allocation concealment, and three of the four RCTs were open-label. Among the six comparisons identified, five were deemed plausible (four with a level of evidence 3 and one with a level of evidence 2). No comparisons were rated at level 1 evidence. As a result, the effectiveness of OMT alone or in combination with orthodontic treatment for the conditions of interest could not be conclusively confirmed. Further well-designed RCTs are needed to confirm or refute this finding and to strengthen the overall evidence base.</p><p><strong>Conclusion: </strong>Although no high-level evidence currently supports the effectiveness of OMT for managing OMDs associated with malocclusion traits, its potential effectiveness remains plausible. Level 2 evidence suggests that OMT may effectively manage OMDs following orthognathic surgery.</p><p><strong>Registration: </strong>Open Science Framework (DOI 10.17605/OSF.IO/M6HNS).</p>","PeriodicalId":11989,"journal":{"name":"European journal of orthodontics","volume":"47 3","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research transparency in articles published in orthodontic journals: is it clear?","authors":"Matthew Chi Hong Yii, Martyn T Cobourne, Nikolaos Pandis, Jadbinder Seehra","doi":"10.1093/ejo/cjaf028","DOIUrl":"https://doi.org/10.1093/ejo/cjaf028","url":null,"abstract":"<p><strong>Background: </strong>Issues regarding research transparency have been highlighted in the literature. The aim of this investigation was to assess the trend of adhering to the reporting of key transparency practices (data sharing, code sharing, COI disclosure, funding disclosure, and protocol registration) by articles published in three leading orthodontic journals.</p><p><strong>Material and methods: </strong>A Scopus database search was undertaken to identify articles published in 2013, 2018 and 2023 in three orthodontic journals. Independent data extraction was performed. Frequency distributions and cross tabulations (COI not disclosed vs COI disclosed) were calculated. Univariable logistic regression was undertaken to detect associations between COI disclosure and publication characteristics, journal type and reporting of transparency practices.</p><p><strong>Results: </strong>1498 articles were analysed. No data sharing statement (60.7%) was commonly cited. The intention to share data was stated in approx. 15% articles. No article stated a code sharing statement. Almost 70% articles had not registered a protocol. A third of articles disclosed the funder or sponsor (32.7.%), while approximately an equal number of articles disclosed (49.1%) or did not disclose (50.9%) any conflict of interest. Articles published in the EJO had higher odds of reporting protocol registration (OR 7.42; 95% CI: 4.55, 12.10; P < .01) and funding disclosure (OR 3.44; 95% CI: 2.52, 4.69; P < .01) compared to AO and AJODO. A COI disclosure statement was more likely to be in articles published in AJODO. The odds of reporting a data sharing statement were higher in articles published in EJO (OR 8.72; 95% CI: 5.72, 13.29; P < .001). Apart from code sharing, improvements over the 5-year intervals in reporting of transparency indicators were evident.</p><p><strong>Limitations: </strong>Only three journals were assessed which may impact the generalisability of the results.</p><p><strong>Conclusions: </strong>Despite improvements over the 5-year intervals, the reporting of research transparency indicators requires improvement in articles published in orthodontic journals. To encourage transparent research conduct and open science practices, journals and their editors should promote reporting of research transparency indicators.</p>","PeriodicalId":11989,"journal":{"name":"European journal of orthodontics","volume":"47 3","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}