European Journal of Oral Sciences最新文献_第5页

Torture victims’ perspective on dental treatment: “Every sign you make, every move you take” – A qualitative study 酷刑受害者对牙科治疗的看法："你的一举一动"--一项定性研究。

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-07-17 DOI: 10.1111/eos.13007

Ann Catrin Høyvik, Tiril Willumsen, Birgit Lie, Per Kristian Hilden

{"title":"Torture victims’ perspective on dental treatment: “Every sign you make, every move you take” – A qualitative study","authors":"Ann Catrin Høyvik, Tiril Willumsen, Birgit Lie, Per Kristian Hilden","doi":"10.1111/eos.13007","DOIUrl":"10.1111/eos.13007","url":null,"abstract":"Torture victims struggling with post-traumatic stress often experience elements in the dental treatment situation that may trigger trauma-related reactions. The aim of the study was to explore intervention strategies that will enable dental health workers to adapt dental treatment to the needs of torture survivors. Exploratory interviews were conducted with 10 torture-exposed resettled refugees with dental treatment experience in Norway. The data was analyzed using qualitative content analysis, which suggested that to minimize trauma-reactions, dental personnel should focus on creating a safe therapeutic space and strengthening the patient's sense of control. Four main categories of clinical advice were proposed: (i) Acquire knowledge about psychology, consequences of torture, cultural differences, trauma-informed care, and the patients’ individual needs; (ii) Recognize the trigger-potential of busyness or delays; (iii) Avoid surprises, such as sudden moves or actions and explore triggers individually, but make sure not to evoke images of interrogation, and; (iv) Provide overview both with respect to visibility in the clinical room, and to predictability regarding the dental treatment. Although undergoing dental treatment may be challenging for torture-exposed individuals, it is possible to reduce the predicaments considerably by making feasible adaptions to the treatment and adopting a trauma-informed approach.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 5","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eos.13007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epigenetic markers of tooth eruption – DNA methylation and histone acetylation 牙齿萌出的表观遗传标记--DNA 甲基化和组蛋白乙酰化。

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-07-16 DOI: 10.1111/eos.13005

Anna Westerlund, Asal Shikhan, Nina Sabel, Farah Asa'ad, Lena Larsson

{"title":"Epigenetic markers of tooth eruption – DNA methylation and histone acetylation","authors":"Anna Westerlund, Asal Shikhan, Nina Sabel, Farah Asa'ad, Lena Larsson","doi":"10.1111/eos.13005","DOIUrl":"10.1111/eos.13005","url":null,"abstract":"The present study aimed to evaluate whether epigenetic markers are expressed in the dental follicles surrounding ectopically erupting teeth. Twenty-one dental follicles were collected in 20 adolescent children through surgical exposure of ectopic teeth. The epigenetic modifications of DNA methylation and histone acetylation were evaluated by immunohistochemistry. The results showed cells positive for DNA-methyltransferase 1 (DNMT1), DNA methyltransferase 3 beta (DNMT3B), ten-eleven translocation-2 (TET2), acetyl-histone H3 (AcH3), acetyl-histone H4 (AcH4), 5-methylcytosine (5mC), and 5-hydroxymethylcytosine (5hmC) were present in all the samples. The levels of epigenetic markers representing active chromatin (5hmC, AcH3, AcH4, and TET2) were statistically significantly higher than those of markers representing inactive chromatin (5mC, DNMT3B, DNMT1). In conclusion, follicles in ectopic teeth display major epigenetic modifications. In the follicles, epigenetic markers associated with the activation of bone-related genes are more abundant than markers associated with the inactivation of bone-related genes.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eos.13005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contribution of initial lymphatics to oral wound healing after tooth extraction 拔牙后初始淋巴管对口腔伤口愈合的贡献。

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-07-11 DOI: 10.1111/eos.13006

Anca Virtej, Larissa Marti, Marek Wagner, Helge Wiig, Ying Xue, Athanasia Bletsa, Ellen Berggreen

{"title":"Contribution of initial lymphatics to oral wound healing after tooth extraction","authors":"Anca Virtej, Larissa Marti, Marek Wagner, Helge Wiig, Ying Xue, Athanasia Bletsa, Ellen Berggreen","doi":"10.1111/eos.13006","DOIUrl":"10.1111/eos.13006","url":null,"abstract":"Lymphatics are involved in the resolution of inflammation and wound healing, but their role in the oral wound healing process after tooth extraction has never been investigated. We therefore sought to evaluate the healing process following the extraction of maxillary molars in two transgenic mouse models: K14-VEGFR3-Ig mice, which lack initial mucosal lymphatic vessels, and K14-VEGFC mice, which have hyperplastic mucosal lymphatics. Maxillary molars were extracted from both transgenic mouse types and their corresponding wild-type (WT) controls. Mucosal and alveolar bone healing were evaluated. A delayed epithelialization and bone regeneration were observed in K14-VEGFR3-Ig mice compared with their WT littermates. The hampered wound closure was accompanied by decreased levels of epidermal growth factor (EGF) and persistent inflammation, characterized by infiltrates of immune cells and elevated levels of pro-inflammatory markers in the wounds. Hyperplastic mucosal lymphatics did not enhance the healing process after tooth extraction in K14-VEGFC mice. The findings indicate that initial mucosal lymphatics play a major role in the initial phase of the oral wound healing process.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eos.13006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Search for a new Editor-in-Chief 寻找新主编

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-07-10 DOI: 10.1111/eos.13004

引用次数: 0

Salutogenic factors and oral health: A potential pathway for addressing health inequalities 致富因素与口腔健康：解决健康不平等问题的潜在途径。

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-06-27 DOI: 10.1111/eos.13003

Waseem Jerjes

引用次数: 0

Aspects of glass and hybridization protocols for bonding of fiber posts to root dentine 纤维桩与根部牙本质粘接的玻璃和杂化规程的各个方面。

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-06-27 DOI: 10.1111/eos.13002

Bárbara Facco Rauber, João Paulo De Carli, Felipe Gomes Dallepiane, Letícia Copatti Dogenski, Fábio Goedel, Doglas Cecchin, Huriel Scartazzini Palhano, Pedro Henrique Corazza, Kauê Farias Collares, Matheus Albino Souza, Ana Paula Farina

{"title":"Aspects of glass and hybridization protocols for bonding of fiber posts to root dentine","authors":"Bárbara Facco Rauber, João Paulo De Carli, Felipe Gomes Dallepiane, Letícia Copatti Dogenski, Fábio Goedel, Doglas Cecchin, Huriel Scartazzini Palhano, Pedro Henrique Corazza, Kauê Farias Collares, Matheus Albino Souza, Ana Paula Farina","doi":"10.1111/eos.13002","DOIUrl":"10.1111/eos.13002","url":null,"abstract":"This study evaluated bond strength of glass fiber posts to root dentin using push-out (PO) and diametral compression (DC), testing glycolic acid as a conditioner and varying dentin moisture. An additional aim was to test whether DC can be an alternative test to PO for bond strength assessment. Eighty bovine teeth were divided into eight groups (n = 10) defined by the use of either 37% glycolic acid or 37% phosphoric acid (PA) on moist or wet dentin before bonding with either Adapter SingleBond/RelyX ARC or One Step Plus/Duo-Link Bisco. Each tooth provided discs with an internal diameter of 2 mm, external diameter of 5 mm, and height of 2 mm, which underwent PO and DC. Finite element analysis (FEA) was carried out on 3D models. When analyzing PO results through linear regression, the highest values of bond strength were observed using glycolic acid on wet dentin in the cervical and middle thirds of the teeth. Analyzing DC results, the only statistical influence on values was the dental thirds. The scatterplot of the DC results and the PO bond strength values indicated no relationship between the results of the two tests (r = 0.03; p = 0.64). PO test detected more sensitive changes in bond strength values than DC.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141467091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The potential mechanism of WT1-associated protein-induced N-6-methyladenosine modification of colony-stimulating factor 2 in the progression of oral squamous cell carcinoma by JAK/STAT3 pathway regulation JAK/STAT3通路调控WT1相关蛋白诱导集落刺激因子2的N-6-甲基腺苷修饰在口腔鳞状细胞癌进展中的潜在机制

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-06-03 DOI: 10.1111/eos.13001

Ruobing Peng, Shengjun Jiang, Zhongzhi Jin

{"title":"The potential mechanism of WT1-associated protein-induced N-6-methyladenosine modification of colony-stimulating factor 2 in the progression of oral squamous cell carcinoma by JAK/STAT3 pathway regulation","authors":"Ruobing Peng, Shengjun Jiang, Zhongzhi Jin","doi":"10.1111/eos.13001","DOIUrl":"10.1111/eos.13001","url":null,"abstract":"Colony-stimulating factor 2 (CSF2) plays a regulatory role in numerous cancers. However, there is needed to investigate the role of CSF2 in oral squamous cell carcinoma (OSCC) malignant phenotype and the specific mechanisms of CSF2 N-6-methyladenosine (m6A) modification. Therefore, we investigated the regulatory mechanism of m6A-modified CSF2 by WT1-associated protein (WTAP) in OSCC via qRT–PCR, western blot, WTAP and CSF2 overexpression in OSCC. In a panel of OSCCs, Kaplan–Meier plot analysis indicated that high expression of CSF2 was associated with poorer prognosis. Cell functional experiments revealed that enrichment of CSF2 promoted the proliferation and migration of OSCC cells by activating the JAK/STAT3 pathway, whereas the reduced expression of CSF2 resulted in the malignant decline of OSCC cells by blocking the JAK/STAT3 pathway. This study also confirmed that WTAP enhanced the m6A level of CSF2 and facilitated the expression of CSF2 and that CSF2 silencing blocked the invasive phenotype of OSCC cells and reversed the malignancy induced by WTAP overexpression. Overall, this study demonstrated that WTAP mediates the m6A modification of CSF2 and the JAK/STAT3 pathway, which plays an oncogenic role in the development of OSCC and can be a target for the treatment of patients with OSCC.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141237314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of residues from bioceramic sealer on the bond interface with universal adhesive in different application modes 不同应用模式下生物陶瓷密封剂残留物对通用粘合剂粘接界面的影响。

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-05-23 DOI: 10.1111/eos.12994

Joatan Lucas de Sousa Gomes Costa, Antonia Patricia Oliveira Barros, Adirson Jorge Junior, Mariana Bena Gelio, Andréa Abi Rached Dantas, Milton Carlos Kuga

{"title":"Influence of residues from bioceramic sealer on the bond interface with universal adhesive in different application modes","authors":"Joatan Lucas de Sousa Gomes Costa, Antonia Patricia Oliveira Barros, Adirson Jorge Junior, Mariana Bena Gelio, Andréa Abi Rached Dantas, Milton Carlos Kuga","doi":"10.1111/eos.12994","DOIUrl":"10.1111/eos.12994","url":null,"abstract":"This study evaluated the effect on adhesive layer thickness, bond strength, and adhesive failure pattern of the application of universal adhesive (Scotchbond Universal) using either manual or rotary brush in dentin previously impregnated with bioceramic sealer (Sealer Plus BC) using a manual brush, at 24 h and 1 year. Eighty-eight bovine crowns were divided into four groups (n = 22) according to the intervention: (i) use of bioceramic sealer and adhesive application using manual brush, (ii) use of bioceramic sealer and adhesive application using rotary brush, (iii) use of resin sealer and adhesive application using manual brush, and (iv) use of resin sealer and adhesive application using rotary brush. Subsequently, specimens were restored with a composite resin (Filtek Z-250). Adhesive layer thickness was evaluated using confocal microscopy. Bond strength was assessed using the microtensile bond strength test, and adhesive failure pattern was evaluated under a stereomicroscope. Data were analyzed using two-way ANOVA/Tukey tests. Specimens where a rotary brush had been used exhibited lower adhesive layer thickness. Specimens treated with resin sealer and using a manual brush showed lower bond strength values and a higher occurrence of adhesive failures at 24 h and 1 year than specimens treated with bioceramic sealer and using rotary brush for adhesive application.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141081041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bisphenol A release from CAD/CAM splint materials CAD/CAM 夹板材料中的双酚 A 释放量。

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-05-22 DOI: 10.1111/eos.12993

Tristan Hampe, Julia Liersch, Bernhard Wiechens, Ralf Bürgers, Sebastian Krohn

{"title":"Bisphenol A release from CAD/CAM splint materials","authors":"Tristan Hampe, Julia Liersch, Bernhard Wiechens, Ralf Bürgers, Sebastian Krohn","doi":"10.1111/eos.12993","DOIUrl":"10.1111/eos.12993","url":null,"abstract":"This study aimed to investigate the bisphenol A (BPA) release from four CAD/CAM splint materials: three polycarbonate-based (DD BioSplint C, Splint Plus Biostar, Temp Premium Flexible) and one polymethylmethacrylate-based (Temp Basic) material. From each material, ten cylindrical samples (n = 40) were immersed in high-performance liquid chromatography (HPLC) grade water following ISO 10993-12 and incubated for 24 h in an incubation shaker at 37°C and 112 rpm. Following BPA derivatization, analysis was performed by high-performance liquid chromatography–tandem mass spectrometry (HPLC-MS/MS). After 24 h of incubation, all investigated materials released significant amounts of BPA compared to water blanks. The material-dependent elution increased in the following order: DD BioSplint C < Splint Plus Biostar < Temp Basic < Temp Premium Flexible. Subtracting extraneous BPA, the concentrations ranged between 2.27 ng/mL and 12.65 ng/mL. After extrapolating the concentrations in relation to the average surface area of occlusal splints, the amount of BPA per mL exceeded the Tolerable Daily Intake (TDI) set by the European Union for a person weighing 70 kg by 1.32–6.16 times. Contrary to the release from previously investigated materials, BPA elution from CAD/CAM splint materials was highly elevated. Considering the increasing adaptation of CAD/CAM techniques, elution from them may represent a relevant BPA source in daily dental practice.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eos.12993","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141081030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adding mechanobiological cell features to finite element analysis of an immediately loaded dental implant 在即时加载的牙科植入物的有限元分析中添加机械生物学细胞特征。

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-05-21 DOI: 10.1111/eos.12992

Poliana Alexandra Martinello, Andrés Felipe Cartagena-Molina, Lucas Kravchychyn Capelletti, Bruno Viezzer Fernandes, Ana Paula Gebert de Oliveira Franco, Emilio Graciliano Ferreira Mercuri, Nara Hellen Campanha Bombarda

{"title":"Adding mechanobiological cell features to finite element analysis of an immediately loaded dental implant","authors":"Poliana Alexandra Martinello, Andrés Felipe Cartagena-Molina, Lucas Kravchychyn Capelletti, Bruno Viezzer Fernandes, Ana Paula Gebert de Oliveira Franco, Emilio Graciliano Ferreira Mercuri, Nara Hellen Campanha Bombarda","doi":"10.1111/eos.12992","DOIUrl":"10.1111/eos.12992","url":null,"abstract":"Finite element analysis (FEA) has been used to analyze the behavior of dental materials, mainly in implantology. However, FEA is a mechanical analysis and few studies have tried to simulate the biological characteristics of the healing process of loaded implants. This study used the rule of mixtures to simulate the biological healing process of immediate implants in an alveolus socket and bone-implant junction interface through FEA. Three-dimensional geometric models of the structures were obtained, and material properties were derived from the literature. The rule of mixtures was used to simulate the healing periods—immediate and early loading, in which the concentration of each cell type, based on in vivo studies, influenced the final elastic moduli. A 100 N occlusal load was simulated in axial and oblique directions. The models were evaluated for maximum and minimum principal strains, and the bone overload was assessed through Frost's mechanostat. There was a higher strain concentration in the healing regions and cortical bone tissue near the cervical portion. The bone overload was higher in the immediate load condition. The method used in this study may help to simulate the biological healing process and could be useful to relate FEA results to clinical practice.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141070263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0