European Journal of Oral Sciences最新文献_第6页

Different adhesive approaches for the bonding of a new universal resin cement to a disilicate glass-ceramic 将新型通用树脂粘接剂与二硅酸盐玻璃陶瓷粘接的不同粘接方法。

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-10-25 DOI: 10.1111/eos.13024

Anna Caroliny Detogni, Vitaliano Gomes Araújo-Neto, Renally Bezerra Wanderley Lima, Mário Alexandre Coelho Sinhoreti

{"title":"Different adhesive approaches for the bonding of a new universal resin cement to a disilicate glass-ceramic","authors":"Anna Caroliny Detogni, Vitaliano Gomes Araújo-Neto, Renally Bezerra Wanderley Lima, Mário Alexandre Coelho Sinhoreti","doi":"10.1111/eos.13024","DOIUrl":"10.1111/eos.13024","url":null,"abstract":"This study aimed to evaluate the shear bond strength (SBS) when bonding a universal resin cement to a disilicate glass-ceramic using different adhesive protocols. Sixty specimens were etched with 10% hydrofluoric acid (HF) for 20 s and assigned to one of four treatment protocols (n = 15): The Positive control protocol comprised use of a universal adhesive system + adhesive resin cement; the Test1 protocol comprised use of a new universal adhesive system + universal resin cement; the Test2 protocol comprised use of a silane coupling agent + universal resin cement; and the use of a universal resin cement without adhesive and silane served as the Negative control. One of the two resin cement cylinders built on each specimen in each group was used to test for 24-h SBS, while the other was thermocycled and then tested for SBS. Data were submitted to two-way ANOVA, Tukey's test, and Weibull analysis. The negative control (24 h) showed the lowest SBS mean value. The Test2 protocol resulted in the highest SBS mean value after thermocycling. Adhesive and mixed failures were prevalent in all groups. No statistical difference in m values was observed among the groups at 24 h. After thermocycling, the two Test protocols showed the highest m values. The m values were significantly lower after thermocycling than at 24 h for all groups. After thermal aging, The Test2 protocol resulted in a statistically significantly higher SBS mean value after thermal aging than seen for the other groups.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 6","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142497523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychological resilience in patients with primary Sjögren's syndrome: effect of involvement of major salivary and lacrimal glands 原发性斯约格伦综合征患者的心理适应能力：主要唾液腺和泪腺受累的影响。

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-10-16 DOI: 10.1111/eos.13022

Esra Sevimli, Seda Günay, Alida Aliyeva, Burcu Aksoy, Farida Fortune, Nevsun Inanc, Gonca Mumcu

{"title":"Psychological resilience in patients with primary Sjögren's syndrome: effect of involvement of major salivary and lacrimal glands","authors":"Esra Sevimli, Seda Günay, Alida Aliyeva, Burcu Aksoy, Farida Fortune, Nevsun Inanc, Gonca Mumcu","doi":"10.1111/eos.13022","DOIUrl":"10.1111/eos.13022","url":null,"abstract":"The aim of this study was to assess whether the involvement of major salivary and lacrimal glands in primary Sjögren's syndrome (pSS) affected the psychological resilience of patients. This cross-sectional study included 116 patients with pSS. Data were collected through clinical examinations, measurement of salivary flow rates (SFRs), and from Schirmer's test, as well as from patient-reported outcome measures (PROMs), such as the European League Against Rheumatism (EULAR) Sjögren's Syndrome Patient Reported Index (ESSPRI), Brief Resilience Scale (BRS), Work Productivity and Activity Impairment (WPAI), Oral Health Impact Profile-14 (OHIP-14), and the Hospital Anxiety and Depression Scale (HADS). Hyposalivation was defined as an unstimulated SFR of ≤0.1 mL/min. The BRS score (mean ± SD = 2.60 ± 0.69) was lower in patients with recurrent parotitis (2.11 ± 0.37) than in those without recurrent parotitis (2.67 ± 0.86), in the whole group. In patients with an unacceptable symptom state (ESSPRI score ≥ 5 points), a lower BRS score was observed in patients with both hyposalivation and ocular dryness (2.59 ± 0.69) than in patients with isolated hyposalivation (2.84 ± 0.84). The BRS score was also negatively associated with the WPAI-Daily Impairment and OHIP-14 scores in patients with hyposalivation as well as with HADS-A (the seven items of HADS relating to the anxiety dimension) and HADS-D (the seven items of HADS relating to the depression dimension) in the whole group. The results suggest that psychological resilience in pSS may be affected by recurrent parotitis, the levels of anxiety and depression, as well as hyposalivation with ocular dryness.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 6","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of propolis added to single-bottle adhesives on water permeation through the hybrid layer 单瓶粘合剂中添加蜂胶对混合层透水性的影响。

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-10-10 DOI: 10.1111/eos.13023

Lucineide Silva da Rocha, Daniela Ferreira de Oliveira, Cinthya Luna Veloso de Lima, Ticiano Gomes do Nascimento, Johnnatan Duarte de Freitas, Jeniffer Mclaine Duarte de Freitas, Isabel Cristina Celerino de Moraes Porto

{"title":"Effect of propolis added to single-bottle adhesives on water permeation through the hybrid layer","authors":"Lucineide Silva da Rocha, Daniela Ferreira de Oliveira, Cinthya Luna Veloso de Lima, Ticiano Gomes do Nascimento, Johnnatan Duarte de Freitas, Jeniffer Mclaine Duarte de Freitas, Isabel Cristina Celerino de Moraes Porto","doi":"10.1111/eos.13023","DOIUrl":"10.1111/eos.13023","url":null,"abstract":"Water treeing and water droplets are observed within adhesive layers and on the hybridized surface after bonding sound dentin using single-bottle etch-and-rinse adhesives, indicating permeability of the hybrid layer to water. The aim of this study was to assess the efficacy of dentin sealing by adhesives containing propolis by quantifying the area of water transudation from dentinal tubules after dentin hybridization. Brazilian red propolis was added to experimental adhesive and Single Bond (3M/ESPE) adhesive; experimental adhesive and Single Bond without propolis were used as controls. Under simulated pulp pressure, two layers of adhesive were applied to etched human dentin discs. Three minutes after light-curing, the hybridized dentin surface was replicated, and epoxy resin replicas were created to obtain scanning electron microscope images. Data were evaluated using ANOVA and Tukey's test. Single Bond containing propolis significantly decreased water permeation through the hybrid layer compared with the control group. Three minutes after polymerization, the experimental adhesive without propolis had formed a permeable hybrid layer. The addition of Brazilian red propolis significantly reduced surface water on hybridized dentin in a concentration-dependent manner. Two-step etch-and-rinse adhesives containing propolis were effective in reducing water permeation through the hybridized dentin surface.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 6","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Three-dimensional finite element analysis of the impact of access cavity preparation on first molar fracture resistance: A scoping review 三维有限元分析检修洞准备对第一磨牙抗折性的影响：范围综述。

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-09-30 DOI: 10.1111/eos.13021

Chuang Zhou, Ruochen Pu, Bin Liu

{"title":"Three-dimensional finite element analysis of the impact of access cavity preparation on first molar fracture resistance: A scoping review","authors":"Chuang Zhou, Ruochen Pu, Bin Liu","doi":"10.1111/eos.13021","DOIUrl":"10.1111/eos.13021","url":null,"abstract":"Access cavity preparation represents the initial step in root canal treatment. Minimally invasive approaches have gained increasing attention and involve advancements in the traditional access cavity preparation. Simultaneously, the development of three-dimensional finite element analysis (3D-FEA) has provided a theoretical foundation for evaluating the merits and drawbacks of various access cavity preparations. Studies using static loading 3D-FEA have suggested that conservative access cavity preparation reduces the concentration of stress in the cervical region, thereby strengthening fracture resistance. However, the lack of support from clinical data raises concerns about the validity of this suggestion. Conversely, studies involving cyclic loading 3D-FEA and dynamic loading 3D-FEA have challenged the prevailing perspectives by taking into account additional factors such as filling materials, thus providing a more comprehensive understanding of the impact of access cavity preparation on fracture resistance. Existing research lacks a comprehensive comparison of the different 3D-FEA methods, and this review fills this gap by providing a systematic assessment of different 3D-FEA methods and their applications in access cavity preparation.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 6","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of sodium copper- and sodium iron-chlorophyllin primers on resin bonding to dentin 铜钠和铁钠叶绿素底漆对牙本质树脂粘合的影响

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-09-24 DOI: 10.1111/eos.13017

Yohsuke Taira, Takafumi Egoshi, Kei Kaida, Shizuka Yamada

{"title":"Effects of sodium copper- and sodium iron-chlorophyllin primers on resin bonding to dentin","authors":"Yohsuke Taira, Takafumi Egoshi, Kei Kaida, Shizuka Yamada","doi":"10.1111/eos.13017","DOIUrl":"https://doi.org/10.1111/eos.13017","url":null,"abstract":"This study evaluated the effects of two chlorophyll derivatives, sodium copper chlorophyllin (Cu-Chl) and sodium iron chlorophyllin (Fe-Chl), on the bond strength between a self-curing luting agent (4-META/MMA-TBB resin) and dentin. Five aqueous primers containing 35% 2-hydroxyethylmethacrylate with 0.007% Cu-Chl, 0.07% Cu-Chl, 0.007% Fe-Chl, 0.07% Fe-Chl, or neither Cu-Chl nor Fe-Chl (no-Chl) were prepared. The extracted human dentin surfaces were etched with 10% phosphoric acid (10PA), primed, and bonded to a resin block using the 4-META/MMA-TBB resin. A conventional etching agent (10-3) and 10PA without primer (PA/no-primer) were used as controls. The microtensile bond strength was determined after 48 h. The arithmetic medians for 20 stick specimens were calculated and statistically analyzed using a nonparametric Steel-Dwass test (α = 0.05). The maximum bond strength was achieved in the 0.007% Cu-Chl group, followed by those in the 0.07% Cu-Chl, 0.07% Fe-Chl, 10-3, 0.007% Fe-Chl, no-Chl, and PA/no-primer groups. No significant difference was observed between 0.007% Fe-Chl, 0.07% Fe-Chl, and 10-3. The bond strength to dentin etched with 10PA was influenced by the type and concentration of the chlorophyll derivatives applied. Cu-Chl rather than Fe-Chl should be useful as a component of surface treatment agents for bonding 4-META/MMA-TBB resin to dentin.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 5","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142324411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of interleukin-17A on inflammatory mediator production in interleukin-1β-stimulated human dental pulp fibroblasts 白细胞介素-17A 对白细胞介素-1β 刺激人牙髓成纤维细胞产生炎症介质的影响

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-09-20 DOI: 10.1111/eos.13019

Tadashi Nakanishi, Katsuhiro Mieda, Hitomi Kuramoto, Daisuke Takegawa

{"title":"Effect of interleukin-17A on inflammatory mediator production in interleukin-1β-stimulated human dental pulp fibroblasts","authors":"Tadashi Nakanishi, Katsuhiro Mieda, Hitomi Kuramoto, Daisuke Takegawa","doi":"10.1111/eos.13019","DOIUrl":"10.1111/eos.13019","url":null,"abstract":"In response to pro-inflammatory cytokines such as interleukin (IL)-1β, dental pulp fibroblasts produce various inflammatory mediators, including IL-6, IL-8, CC chemokine ligand 20 (CCL20), and CXC chemokine ligand 10 (CXCL10), leading to the progression of pulpitis. IL-17/IL-17A (IL-17A) is a pro-inflammatory cytokine secreted by T helper (Th) 17 cells following their recruitment to inflamed sites; however, the roles of IL-17A during pulpitis remain unclear. The purpose of this study was to investigate the effect of IL-17A on IL-6, IL-8, CCL20 and CXCL10 production by human dental pulp fibroblasts (HDPFs) in vitro. IL-17A at a concentration of 100 ng/ml induced the production of 10 times more IL-8 and 4 times more CXCL10, but not IL-6 and CCL20, compared to controls. Co-stimulation of HDPFs with IL-17A and IL-1β synergistically enhanced the production of IL-6, CCL20, IL-8 and CXCL10. IL-1β increased expression of IL-17 receptor/IL-17RA (IL-17R) on HDPFs. Moreover, the cell signal pathways of p38 mitogen-activated protein kinase (MAPK) and nuclear factor-κB (NF-κB) were more potently activated by simultaneous stimulation with IL-17A and IL-1β. These findings suggest that IL-17A participates in the progression of dental pulp inflammation through the enhanced production of inflammatory mediators in HDPFs.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 5","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of peroxide-free and peroxide-based in-office bleaching on the surface and mechanical properties of CAD/CAM esthetic restorative materials 不含过氧化物和含过氧化物的诊室漂白对 CAD/CAM 美学修复材料表面和机械性能的影响

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-09-13 DOI: 10.1111/eos.13016

Majed M. Alsarani, Aftab Ahmed Khan, Leonel S. J. Bautista, Hanan Alsunbul, Jukka P. Matinlinna

{"title":"Effect of peroxide-free and peroxide-based in-office bleaching on the surface and mechanical properties of CAD/CAM esthetic restorative materials","authors":"Majed M. Alsarani, Aftab Ahmed Khan, Leonel S. J. Bautista, Hanan Alsunbul, Jukka P. Matinlinna","doi":"10.1111/eos.13016","DOIUrl":"10.1111/eos.13016","url":null,"abstract":"The study aimed to investigate the influence of H2O2-based and H2O2-free in-office bleaching on the surface and mechanical attributes of CAD/CAM composite blocks. CAD/CAM composite blocks from five different composite materials (CC1, CC2, CC3, CC4, and CC5) were randomly divided into two groups according to bleaching application (H2O2-based and H2O2-free). The surface topography, morphology, nanohardness, elastic modulus, flexural strength, and fracture toughness were measured. A paired and unpaired sample t-tests gauged the effect of pre- and post-bleaching on the substrates. The estimated mean differences (before-after bleaching) suggested an increase in surface roughness for two materials CC2 and CC4, and a significant decrease in nanohardness for material CC4 and in elastic modulus for materials CC2 and CC4 with H2O2-based bleaching, whereas H2O2-free bleaching resulted in changes compatible with no change in these properties. Flexural strength and fracture toughness showed no evidence of changes, irrespective of the bleaching gel used. Scanning electron microscopic analysis revealed erosive effects and micropore formation due to H2O2-based bleaching. H2O2-based bleaching deteriorates the surface of CAD/CAM composite materials while H2O2-free bleaching gel had an insignificant effect on both surface and bulk properties. The clinician should carefully evaluate the potential effects of H2O2-based bleaching on the surface properties of CAD/CAM composites.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 5","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of blockage of Trem1 on the M1 polarization of macrophages in the regulation dental pulp inflammation 阻断 Trem1 对调控牙髓炎症中巨噬细胞 M1 极化的影响

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-09-12 DOI: 10.1111/eos.13018

Ting-Ting Wang, Wen-Rui Jiang, Li Xu, Mei-Yun Zhou, Yong-Song Huang

引用次数: 0

Effect of combining aminomethacrylate and fluoride against erosive and abrasive challenges on enamel and dentin 结合使用氨基甲基丙烯酸酯和氟化物对珐琅质和牙本质的腐蚀性和磨蚀性挑战的影响。

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-08-29 DOI: 10.1111/eos.13015

Marina Gullo Augusto, Luis Felipe Oliveira da Silva, Giovanna Lotto, Tamires Maria de Andrade Santos, Idalina Vieira Aoki, Carlos Rocha Gomes Torres, Tais Scaramucci, Alessandra Bühler Borges

{"title":"Effect of combining aminomethacrylate and fluoride against erosive and abrasive challenges on enamel and dentin","authors":"Marina Gullo Augusto, Luis Felipe Oliveira da Silva, Giovanna Lotto, Tamires Maria de Andrade Santos, Idalina Vieira Aoki, Carlos Rocha Gomes Torres, Tais Scaramucci, Alessandra Bühler Borges","doi":"10.1111/eos.13015","DOIUrl":"10.1111/eos.13015","url":null,"abstract":"This study evaluated the effect of solutions containing aminomethacrylate copolymer (AA) and sodium fluoride (F; 225 ppm F−) or fluoride plus stannous chloride (FSn; 225 ppm F−, 800 ppm Sn2+) against enamel and dentin erosion/abrasion. Solutions F, FSn, AA, F+AA, FSn+AA, and deionized water as negative control were tested. Bovine enamel and dentin specimens (n = 13/solution/substrate) underwent a set of erosion-abrasion cycles (0.3% citric acid [5 min, 4×/day], human saliva [1 h, 4×/day], brushing [15 s, 2×/day], and treatments [2 min, 2×/day]) for each of five days. Initial enamel erosion was evaluated using Knoop microhardness after the first and second acid challenge on day 1, and surface loss with profilometry after day 5. KOH-soluble fluoride was assessed. Data were analyzed with ANOVA/Tukey tests. The combination of fluoride and AA resulted in higher protection against enamel erosion, whereas this was not the case for the combination of AA and FSn. All treatments protected against enamel and dentin loss. The lowest surface loss values were observed with F+AA and FSn+AA. The polymer did not significantly influence the KOH-soluble fluoride formation on enamel/dentin specimens. The aminomethacrylate copolymer effectively enhanced the efficacy of sodium fluoride against initial erosion and improved the control of enamel and dentin wear of F and FSn solutions.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 5","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of estrogen depression on alveolar bone microarchitecture and periodontal ligament cells during orthodontic movement 雌激素抑制对正畸过程中牙槽骨微结构和牙周韧带细胞的影响

IF 1.8 4区医学

European Journal of Oral Sciences Pub Date : 2024-08-19 DOI: 10.1111/eos.13014

Andréa Karina Ruivo, Bruno Calsa, Matheus Gomez Cancellara, João Paulo Nascimento Lima, Karla Rovaris da Silva, Marcelo Augusto Marretto Esquisatto, Milton Santamaria-Jr

{"title":"Effect of estrogen depression on alveolar bone microarchitecture and periodontal ligament cells during orthodontic movement","authors":"Andréa Karina Ruivo, Bruno Calsa, Matheus Gomez Cancellara, João Paulo Nascimento Lima, Karla Rovaris da Silva, Marcelo Augusto Marretto Esquisatto, Milton Santamaria-Jr","doi":"10.1111/eos.13014","DOIUrl":"10.1111/eos.13014","url":null,"abstract":"This study aimed to evaluate the effects of the estrogen depression during orthodontic tooth movement on alveolar bone microarchitecture and periodontal ligament. Female Wistar rats were divided into two groups, one consisting of non-ovariectomized animals subjected to orthodontic tooth movement, and one comprising ovariectomized animals subjected to orthodontic tooth movement. Micro-CT assessment of bone volume to total volume (BV/TV), total porosity, trabecular thickness (Tb.Th), trabecular number (Tb.N), and trabecular separation (Tb.Sp) in the alveolar bone of the orthodontically moved tooth was performed. Histomorphometric analyses were made in the periodontal ligament, and immunoexpression of RANK, RANKL, OPG, and TUNEL were quantified. Orthodontic tooth movement in the group of ovariectomized rats was faster than in non-ovariectomized animals. The alveolar bone area showed lower values of BV/TV and trabecular thickness, and higher bone porosity and trabeculae numbers in the ovariectomized rats. Histological analyses in the ovariectomized group revealed an increase in collagen fibers in the periodontal ligament. The apoptotic cell counts in the periodontal ligament were higher in the group of ovariectomized rats than in the sham-operated rats. Ovariectomy resulted in an increase in tooth movement and alteration of the alveolar bone microstructure in the first 7 day of orthodontic tooth movement, and in the presence of apoptotic cells in the periodontal ligament.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"132 5","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142003976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0