European Journal of Oral Sciences最新文献

Clinical comparison of mouthrinse and orodispersible film containing cystatins and a statherin-derived peptide against initial dental erosion. 含半胱他汀类药物和半胱他汀类药物衍生肽的漱口水和口腔分散膜抗初始牙侵蚀的临床比较。

IF 2 4区医学

European Journal of Oral Sciences Pub Date : 2026-10-16 DOI: 10.1111/eos.70154

Marília Afonso Rabelo Buzalaf, Even Akemi Taira, Gustavo Cassalate da Silva, Mariana Miranda de Brito, Talita Mendes Oliveira Ventura, Flávio Henrique-Silva, João Guilherme Medeiros, Thiago Saads Carvalho, Andrea Soares da Costa Fuentes, Karina Fan, Reinaldo Marchetto, Adrian Lussi, Vinícius Taioqui Pelá

{"title":"Clinical comparison of mouthrinse and orodispersible film containing cystatins and a statherin-derived peptide against initial dental erosion.","authors":"Marília Afonso Rabelo Buzalaf, Even Akemi Taira, Gustavo Cassalate da Silva, Mariana Miranda de Brito, Talita Mendes Oliveira Ventura, Flávio Henrique-Silva, João Guilherme Medeiros, Thiago Saads Carvalho, Andrea Soares da Costa Fuentes, Karina Fan, Reinaldo Marchetto, Adrian Lussi, Vinícius Taioqui Pelá","doi":"10.1111/eos.70154","DOIUrl":"https://doi.org/10.1111/eos.70154","url":null,"abstract":"This randomized crossover in vivo study compared the anti-erosive efficacy of solution and orodispersible film (ODF) formulations containing three cystatins (CaneCPI-5, MaquiCPI-3, and CsinCPI-2) combined with a statherin-derived peptide (StN15pSpS). Ten participants completed six experimental phases: negative controls (water or placebo ODF), positive controls (Elmex or NaF-containing ODF), and experimental formulations (solution or ODF containing proteins/peptide). After prophylaxis and baseline surface reflection intensity (SRI) measurement, treatments were applied (1 min), followed by acquired enamel pellicle formation (2 h), an erosive challenge (15 s), and final SRI assessment. Calcium release was determined by Arsenazo III method. Questionnaires evaluating satisfaction, preference, and safety were also applied. Two-way anova showed a significant treatment effect, but no effect of vehicle or treatment-vehicle interaction (p < 0.05). Both experimental formulations yielded higher percentage SRI values than their respective negative controls. The experimental ODF outperformed the NaF-ODF, whereas the experimental solution was comparable to Elmex. The experimental ODF reduced calcium release compared with placebo, whereas the experimental solution did not differ from water and released more calcium than Elmex. Participants preferred the ODF, considering it more practical and convenient. Both formulations prevented initial dental erosion in vivo, with the ODF showing promising efficacy and greater user acceptance.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":" ","pages":"e70154"},"PeriodicalIF":2.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between serum cotinine and risk of tooth loss in adults: A comprehensive statistical framework and molecular mechanisms. 成人血清可替宁与牙齿脱落风险的关系：一个全面的统计框架和分子机制。

IF 2 4区医学

European Journal of Oral Sciences Pub Date : 2026-10-14 DOI: 10.1111/eos.70156

Xiangji Dang, Ruifeng Yang, Hongjie Li, Jiaqi Liu, Juan Jiang, Zhuolin Qin, Longqian Li, Yan Liu

{"title":"Relationship between serum cotinine and risk of tooth loss in adults: A comprehensive statistical framework and molecular mechanisms.","authors":"Xiangji Dang, Ruifeng Yang, Hongjie Li, Jiaqi Liu, Juan Jiang, Zhuolin Qin, Longqian Li, Yan Liu","doi":"10.1111/eos.70156","DOIUrl":"https://doi.org/10.1111/eos.70156","url":null,"abstract":"This study aimed to investigate the association between serum cotinine (a tobacco exposure biomarker) and tooth loss risk in adults. This study employed a statistical framework incorporating logistic regression, restricted cubic spline (RCS), machine learning, and web page construction to investigate the association between serum cotinine levels and tooth loss in 12,559 adult National Health and Nutrition Examination Survey participants. Network pharmacology was used to identify key targets, whereas molecular docking explored the specific mechanism of cotinine's impact on the target protein. Logistic regression and RCS demonstrated a positive (odds ratios = 1.106, 95% confidence interval: 1.085 to 1.127, p < 0.0001) and nonlinear (p for nonlinear < 0.0001) correlation between serum cotinine and tooth loss. After re-identifying 14 core genes via network pharmacology, molecular docking was employed to verify the specific protein molecular mechanism of cotinine's effect on tooth loss. Six different molecular docking methods were used to explain the specific molecular mechanism. The highest affinity of -7.3 kcal/mol was observed for the GSK3B-cotinine interaction. This study showed high serum cotinine levels strongly tied to greater tooth loss risk in adults, likely via core proteins controlling cell cycle and inflammation. Antioxidants partly reduced this risk, laying groundwork for early prevention and targeted treatments of tobacco-linked oral issues.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":" ","pages":"e70156"},"PeriodicalIF":2.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149180143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Titanium and zinc fluorides inhibit salivary matrix metalloproteinases at low concentrations. 低浓度氟化钛和氟化锌抑制唾液基质金属蛋白酶。

IF 2 4区医学

European Journal of Oral Sciences Pub Date : 2026-10-14 DOI: 10.1111/eos.70153

Eliana do Nascimento Torre, Rodrigo Varella de Carvalho, Rafael Guerra Lund, Josué Martos, Adriana Etges

{"title":"Titanium and zinc fluorides inhibit salivary matrix metalloproteinases at low concentrations.","authors":"Eliana do Nascimento Torre, Rodrigo Varella de Carvalho, Rafael Guerra Lund, Josué Martos, Adriana Etges","doi":"10.1111/eos.70153","DOIUrl":"https://doi.org/10.1111/eos.70153","url":null,"abstract":"To evaluate the inhibition of the activity of salivary matrix metalloproteinases (MMPs) (MMP-2 and MMP-9) by solutions of titanium tetrafluoride (TiF4), zinc fluoride (ZnF2), stannous fluoride (SnF2), and sodium fluoride (NaF). Saliva was collected from eight healthy individuals. Pooled saliva was centrifuged; the supernatants were incubated for 2 h (26°C) and subjected to gelatin zymography. TiF4, ZnF2, SnF2, and NaF, were added into the incubation buffer in clinically relevant concentrations (0.01-2 wt%). The electrophoretic bands were scanned, and the transmittance values were analyzed with imagej software. Four bands were detected in the control group, two bands less clear, close to the molecular weight of 70 kDa and two more evident bands, close to 90 kDa. These enzymes were characterized as MMPs, as their activities were inhibited by ethylenediaminetetraacetic acid and not inhibited by N-ethylmaleimide. All tested fluorides were able to inhibit at least partially the activity of salivary MMPs. TiF4 and ZnF2 had an inhibitory effect at all tested concentrations, whereas at 0.01% and 0.05% NaF and SnF2 suppressed only partially MMPs activity. In conclusion, TiF4 and ZnF2 were able to completely inhibit MMPs expression even at very low concentrations, whereas the effect of NaF and SnF2 was dose dependent.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":" ","pages":"e70153"},"PeriodicalIF":2.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149180146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of cuproptosis in periodontitis: Current advances and future perspectives. 铜突在牙周炎中的作用：目前的进展和未来的展望。

IF 2 4区医学

European Journal of Oral Sciences Pub Date : 2026-10-14 DOI: 10.1111/eos.70158

Qiqi Shi, Xu Qin, Chenxi Jiang, Guangxun Zhu

引用次数: 0

Using grape seed extract to reduce erosive potential of drinks. 使用葡萄籽提取物降低饮料的腐蚀潜力。

IF 2 4区医学

European Journal of Oral Sciences Pub Date : 2026-10-14 DOI: 10.1111/eos.70151

Samira Helena Niemeyer, Jessica Schuler, Sara Kim Plüss, Tommy Baumann, Florian Just Wegehaupt, Thiago Saads Carvalho

{"title":"Using grape seed extract to reduce erosive potential of drinks.","authors":"Samira Helena Niemeyer, Jessica Schuler, Sara Kim Plüss, Tommy Baumann, Florian Just Wegehaupt, Thiago Saads Carvalho","doi":"10.1111/eos.70151","DOIUrl":"https://doi.org/10.1111/eos.70151","url":null,"abstract":"The aim of this study was to verify whether supplementation of grape seed extract (GSE) to different erosive beverages reduces their erosive potential on dentine in vitro. One-hundred dentine specimens were randomly assigned to 5 groups (n = 20/group): control-deionized water, 1%-citric acid, Red Bull, Coca-Cola, and Powerade. These groups were further subdivided into 2 subgroups (n = 10/subgroup): with and without GSE. Specimens were immersed into the respective solution (6 min, 25°C, shaking), washed with deionized water, slightly dried, and immersed in a mineral solution (60 min, pH 7.4, 37°C, not shaking). This was repeated 10 times. Dentine surface loss (dSL) was measured using an optical profilometer, and data were analyzed using Kruskal-Wallis with post hoc Dunn's tests and Bonferroni corrections for multiple comparisons (α = 0.05). The effect of GSE within each solution was analyzed with Mann-Whitney U test. Without supplementation, Coca-Cola and Powerade caused the greatest dSL, whereas citric acid and Red Bull caused some dSL. Supplementation with GSE significantly reduced dSL for all erosive beverages (p < 0.01). The control group caused no dentine loss, regardless of the presence of GSE. Supplementation of sports or soft drinks with GSE reduces their erosive potential on dentine and could be used as a preventive strategy against dental erosion, especially among frequent consumers of these beverages.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":" ","pages":"e70151"},"PeriodicalIF":2.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149180204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond binary dentistry: Should artificial intelligence think more like clinicians? 超越二元牙科：人工智能是否应该更像临床医生一样思考？

IF 2 4区医学

European Journal of Oral Sciences Pub Date : 2026-10-12 DOI: 10.1111/eos.70155

Mohammed Turky, Paul M H Dummer

{"title":"Beyond binary dentistry: Should artificial intelligence think more like clinicians?","authors":"Mohammed Turky, Paul M H Dummer","doi":"10.1111/eos.70155","DOIUrl":"https://doi.org/10.1111/eos.70155","url":null,"abstract":"Artificial intelligence (AI) is increasingly influencing dental diagnosis and clinical decision-making, yet many AI systems continue to represent disease and treatment outcomes through discrete categories. Although binary classification has contributed substantially to diagnostic performance, it does not always reflect how clinicians reason in practice. Dental decisions are frequently made under incomplete information, biological variability, and competing clinical findings, requiring dentists to weigh probabilities, alternative explanations, and degrees of confidence rather than simply choosing between two outcomes. This short communication argues that future dental AI should better represent this inherent clinical uncertainty. Fuzzy logic provides one possible conceptual framework, allowing partial membership and graded states rather than forcing complex biological conditions into rigid categories. Its potential value in dentistry extends beyond computation: it may help AI communicate uncertainty in ways that are more consistent with clinical reasoning. Such systems could provide graded diagnostic confidence, competing possibilities, or degrees of treatment suitability, rather than presenting apparently definitive answers. This approach may also support explainability and reduce inappropriate reliance on algorithmic recommendations. The future of dental AI may therefore depend not only on improving predictive accuracy, but also on representing the grey zones in which much of clinical dentistry takes place.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":" ","pages":"e70155"},"PeriodicalIF":2.0,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Charting the course of Sjögren's disease: A historical analysis of scientific progress. 绘制Sjögren疾病的病程：科学进步的历史分析。

IF 2 4区医学

European Journal of Oral Sciences Pub Date : 2026-09-30 DOI: 10.1111/eos.70147

Diego Ustárroz Cantali, Fabiola Reis de Oliveira, Denise Cantarelli Machado, Moisés Evandro Bauer

{"title":"Charting the course of Sjögren's disease: A historical analysis of scientific progress.","authors":"Diego Ustárroz Cantali, Fabiola Reis de Oliveira, Denise Cantarelli Machado, Moisés Evandro Bauer","doi":"10.1111/eos.70147","DOIUrl":"https://doi.org/10.1111/eos.70147","url":null,"abstract":"Sjögren's disease (SjD) bears the name of the Swedish ophthalmologist Henrik Sjögren. His 1933 doctoral thesis on keratoconjunctivitis sicca ignited interest, yet much remains under debate. SjD is an autoimmune disorder that primarily affects the exocrine glands, particularly the salivary and lacrimal glands, leading to a dryness of the eyes and mouth. Diagnostic criteria have evolved significantly, with over 10 classification criteria proposed since 1965. From its inception, SjD was often overshadowed by other rheumatic diseases, struggling for recognition as a distinct autoimmune entity. Early research in the 1960s and 1970s led to inconsistent nomenclature for autoantibodies, further complicating understanding. Although Sjögren studied biopsies early on, standardized approaches to biopsy sites and histological findings took considerable time to establish. Recent advancements, such as the introduction of salivary gland ultrasound as a non-invasive diagnostic tool, have offered new avenues for investigation. However, challenges persist in accurately assessing disease activity due to the wide range of manifestations. This narrative and historical review explores the evolution of Sjögren's syndrome as a distinct disease, tracing its history from initial descriptions to contemporary developments.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":" ","pages":"e70147"},"PeriodicalIF":2.0,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149080124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of repeated firing on hardness and elasticity of fully crystallized computer-aided design/computer-aided manufacturing lithium disilicate ceramics. 重复烧成对全结晶计算机辅助设计/计算机辅助制造二硅酸锂陶瓷硬度和弹性的影响。

IF 2 4区医学

European Journal of Oral Sciences Pub Date : 2026-09-30 DOI: 10.1111/eos.70148

Maria Kiatipi, Petros Mourouzis, Dimitrios Dionysopoulos, Anna Theocharidou, Kosmas Tolidis

{"title":"The effect of repeated firing on hardness and elasticity of fully crystallized computer-aided design/computer-aided manufacturing lithium disilicate ceramics.","authors":"Maria Kiatipi, Petros Mourouzis, Dimitrios Dionysopoulos, Anna Theocharidou, Kosmas Tolidis","doi":"10.1111/eos.70148","DOIUrl":"https://doi.org/10.1111/eos.70148","url":null,"abstract":"The aim of this study was to evaluate the hardness and elastic properties of various computer-aided design (CAD)/computer-aided manufacturing lithium disilicate ceramics, including IPS e.max CAD, GC Initial LiSi Block and CEREC Tessera and to assess the impact of repeated firings on these characteristics. Sixty fully crystallized square-plate specimens were generated, 20 for each evaluated material (n = 20), and were subjected to two additional firings. Initially and after each additional firing, hardness and modulus values were measured with a nanoindentation tester. Changes in microstructure and elemental composition were analyzed by field emission scanning electron microscopy and energy-dispersive x-ray spectroscopy. Statistical analysis was conducted in RStudio using linear mixed-effects models, with significance set at α = 0.05. Across all firing cycle protocols, CEREC Tessera specimens exhibited higher Martens hardness values than those of IPS e.max CAD and GC Initial LiSi Block. Firing had the greatest effect on hardness and indentation modulus, with all parameters showing a consistent peak after the first additional firing.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":" ","pages":"e70148"},"PeriodicalIF":2.0,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149080087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fibroblast and bacterial adhesion on a 3D-printed polyetheretherketone-based implant material. 成纤维细胞和细菌粘附在3d打印聚醚酮基植入材料上。

IF 2 4区医学

European Journal of Oral Sciences Pub Date : 2026-09-30 DOI: 10.1111/eos.70146

Rafaela Branco, Raphael de Souza, Nesma El-Amier, Neusa Silva, Elizabeth Zimmermann, António Mata, Joana Marques

{"title":"Fibroblast and bacterial adhesion on a 3D-printed polyetheretherketone-based implant material.","authors":"Rafaela Branco, Raphael de Souza, Nesma El-Amier, Neusa Silva, Elizabeth Zimmermann, António Mata, Joana Marques","doi":"10.1111/eos.70146","DOIUrl":"https://doi.org/10.1111/eos.70146","url":null,"abstract":"This study investigated fibroblast and bacteria proliferation on polyetheretherketone (PEEK)-implant material 3D-printed by fused deposition modeling (FDM) in comparison to titanium (cp-Ti) and zirconia (ZrO2). Four groups were tested, including horizontally FDM-printed PEEK (PH), vertically printed FDM-PEEK (printed vertically [PV]), cp-Ti and ZrO2. Human gingival fibroblasts were cultured on discs (15/group), with viability evaluated at 1-, 3-, and 7-d and cytokine production (IL-6 and IL-8) measured at 3-d. Discs (9/group) were exposed to Streptococcus oralis with bacteria counted at 1- and 2-d. Discs underwent scanning electron microscopy and surface roughness testing. Although fibroblast proliferation was similar for all groups at 24 h, values were significantly higher for PV than ZrO2 at 3-d. At 7-d, fibroblast proliferation was significantly lower on PH than cp-Ti. Bacterial adhesion for ZrO2 was lower than other groups at 24 h and lower than PV and PH at 48 h. IL-8 production was similar between groups, whereas IL-6 was higher on cp-Ti compared to ZrO2. PV was significantly rougher than other groups. FDM-PEEK induces early fibroblast adhesion and viability and bacterial colonization comparable to reference implant materials. The positive outcomes of this study underscore FDM-PEEK as a promising biomaterial comparable to established implant and prosthetic materials in terms of favorable biological responses and potential soft-tissue seal.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":" ","pages":"e70146"},"PeriodicalIF":2.0,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149080117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trends and regional variation in antibiotic prescribing by dentists in Finland, 2012-2025: A register-based study. 2012-2025年芬兰牙医抗生素处方的趋势和地区差异：一项基于登记的研究。

IF 2 4区医学

European Journal of Oral Sciences Pub Date : 2026-09-23 DOI: 10.1111/eos.70145

Terhi Laitala, Emma Aarnio, Katariina Tuomilinna, Eero Raittio, Jukka Leinonen

{"title":"Trends and regional variation in antibiotic prescribing by dentists in Finland, 2012-2025: A register-based study.","authors":"Terhi Laitala, Emma Aarnio, Katariina Tuomilinna, Eero Raittio, Jukka Leinonen","doi":"10.1111/eos.70145","DOIUrl":"https://doi.org/10.1111/eos.70145","url":null,"abstract":"This nationwide register-based study aimed to investigate trends and regional variation in the number of antibiotic prescriptions issued by dentists in Finland from 2012 to 2025. Data on reimbursed outpatient antibiotic prescriptions dispensed by Finnish pharmacies were used. Prescriptions were identified using Anatomical Therapeutic Chemical codes and categorized by prescriber, antibiotic type and county. Annual prescription rates per 100,000 inhabitants were calculated. County-level variation was analysed for 2019-2025 using negative binomial regression, adjusting for population size. The overall antibiotic prescribing rate by Finnish dentists increased by 9% from 2012 to 2015 but then declined so that the rate in 2019 was 15% lower than in 2012. Phenoxymethylpenicillin was the most frequently prescribed antibiotic, and its prescribing decreased by 28% in 2012-2019. Excluding phenoxymethylpenicillin, for which data were unavailable after 2019, the overall antibiotic prescribing rate decreased by 16% in 2012-2025. Prescribing of amoxicillin increased by 41%, whereas prescribing of clindamycin decreased by 74% and that of doxycycline by 79%. There were up to 3- to 4-fold differences between counties in antibiotic prescription rates by dentists. Overall, there was a modest decline in the overall antibiotic prescribing rate by Finnish dentists, but regional variation in antibiotic prescribing was substantial.","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":" ","pages":"e70145"},"PeriodicalIF":2.0,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149024189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0