European Journal of Oral Sciences最新文献

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Current perspective on dental black stain of bacterial origin: A narrative review 细菌性牙黑色斑的研究现状:综述。
IF 1.8 4区 医学
European Journal of Oral Sciences Pub Date : 2025-02-24 DOI: 10.1111/eos.70007
Ahmed Al-Shareef, Raquel González-Martínez, Isidoro Cortell-Ballester, Mar Jovani-Sancho, Chirag C. Sheth, Veronica Veses
{"title":"Current perspective on dental black stain of bacterial origin: A narrative review","authors":"Ahmed Al-Shareef,&nbsp;Raquel González-Martínez,&nbsp;Isidoro Cortell-Ballester,&nbsp;Mar Jovani-Sancho,&nbsp;Chirag C. Sheth,&nbsp;Veronica Veses","doi":"10.1111/eos.70007","DOIUrl":"10.1111/eos.70007","url":null,"abstract":"<p>Dental black stain is a form of external discoloration appearing as a dark line or an incomplete coalescence of dark spots in the cervical third of the tooth. This review aims to provide an up-to-date clinical and biological summary of dental black stain of bacterial origin. Black stain is esthetically unwelcome to patients, and clinicians frequently attempt its removal. Dental black plaque has a prevalence rate of 2.4%–20% affecting both genders equally and may appear throughout the lifetime. Most studies investigating the microflora of black stain reveal that <i>Actinomyces</i> spp. are the most abundant species found. Most authors have found a correlation between black stain and a low caries incidence. Interestingly, individuals with black stain demonstrate higher salivary concentrations of iron, sodium, copper, and calcium/phosphate, higher pH, and lower salivary flow. Standard treatment involves repeated professional ultrasonic cleaning. Alternative treatments include photo-dynamic therapy, application of virgin coconut oil, peroxide therapy, lactoferrin, or oral probiotics. Our best interpretation of the causes implicates the involvement of oral bacteria, resulting in the deposition of iron ions in patients with altered salivary composition. The use of any treatments should be balanced against potential damage to the teeth as a result of the therapy.</p>","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"133 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strengthening effect of flavonoid antioxidant on resin–enamel bond strength following tooth bleaching 黄酮类抗氧化剂对牙齿漂白后树脂-牙釉质结合强度的增强作用。
IF 1.8 4区 医学
European Journal of Oral Sciences Pub Date : 2025-02-23 DOI: 10.1111/eos.70004
Gabriela Luiza Moreira Carvalho, Bruna Tavares Carneiro, Matheus Kury, Bruna Marin Fronza, Fernanda Novais Arantes Maciel de Castro, Mayara Zaghi Dal Picolo, Vanessa Cavalli, Carolina Bosso André
{"title":"Strengthening effect of flavonoid antioxidant on resin–enamel bond strength following tooth bleaching","authors":"Gabriela Luiza Moreira Carvalho,&nbsp;Bruna Tavares Carneiro,&nbsp;Matheus Kury,&nbsp;Bruna Marin Fronza,&nbsp;Fernanda Novais Arantes Maciel de Castro,&nbsp;Mayara Zaghi Dal Picolo,&nbsp;Vanessa Cavalli,&nbsp;Carolina Bosso André","doi":"10.1111/eos.70004","DOIUrl":"10.1111/eos.70004","url":null,"abstract":"<p>This study aimed to assess the impact of flavonoid-based antioxidant application after in-office bleaching with 35% hydrogen peroxide on the shear bond strength of resin to bovine enamel, comparing it with 10% sodium ascorbate. Bovine enamel blocks (<i>n</i> = 10) were randomly assigned to one of five pretreatments: (i) no bleaching, (ii) bleaching without antioxidant application, and (iii) bleaching followed by a 1-min application of 10% sodium ascorbate, (iv) 5% naringin, or (v) 10% naringin. Color analysis was conducted using a digital spectrophotometer. Shear bond strength was assessed on two, 2-mm-diameter resin cylinders per block using a universal testing machine at 0.5 mm/min until fracture. Enamel surface morphology was analyzed using scanning electron microscopy. Shear bond strength values and color parameters (ΔE<sub>ab</sub>, ΔE<sub>00</sub>, and ΔWI<sub>D</sub>) were analyzed using one-way ANOVA, while <i>t</i>-tests were used for the individual color parameters lightness (<i>L</i>*), green–red (<i>a</i>*), blue–yellow (<i>b</i>*), and chroma (<i>C</i>*)\u0000. None of the antioxidants resulted in bond strength values as high as those observed without bleaching. However, application of sodium ascorbate and 5% naringin after bleaching significantly increased bond strength compared with bleached enamel without antioxidant. Antioxidants had no significant impact on color. The predominant failure modes were adhesive between the adhesive and enamel, and mixed.</p>","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"133 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of nitrogen atmosphere during 3D printing on mechanical properties of orthodontic aligners 3D打印过程中氮气气氛对正畸矫直器力学性能的影响。
IF 1.8 4区 医学
European Journal of Oral Sciences Pub Date : 2025-02-21 DOI: 10.1111/eos.70008
Spiros Zinelis, Nearchos Panayi, Georgios Polychronis, Dimitrios Dionysopoulos, Spyridon N. Papageorgiou, Theodore Eliades
{"title":"Effect of nitrogen atmosphere during 3D printing on mechanical properties of orthodontic aligners","authors":"Spiros Zinelis,&nbsp;Nearchos Panayi,&nbsp;Georgios Polychronis,&nbsp;Dimitrios Dionysopoulos,&nbsp;Spyridon N. Papageorgiou,&nbsp;Theodore Eliades","doi":"10.1111/eos.70008","DOIUrl":"10.1111/eos.70008","url":null,"abstract":"<p>The aim of this study was to investigate the effect of low oxygen environment during printing on the mechanical properties of 3D printed aligners. Thirty-six 3D printed rectangular (20 × 20 × 10 mm) specimens were fabricated using the SprintRay Pro 55 printer and equally divided into two groups. Eighteen of them were built under normal atmosphere conditions during printing (CON) and the rest by continuously purging pure (NIT), thereby eliminating the oxygen content. Both groups underwent post-curing in an illuminated chamber. Three samples from each group were analyzed by attenuated total reflection Fourier-transform infrared spectroscopy (ATR-FTIR). The remaining specimens underwent metallographic grinding/polishing followed by nano-indentation testing. The mechanical properties measured were: Martens Hardness (HM), indentation modulus (E<sub>IT</sub>), and elastic index (η<sub>IT</sub>). Statistically significant differences between groups were assessed using Mann–Whitney tests (<i>α</i> = 0.05). Both groups showed identical ATR-FTIR spectra and complete C = C conversion. No statistically significant differences in the parameters tested were seen. The medians (interquartile ranges) were HM CON: 68.0 N/mm<sup>2</sup> (65.0–71.0 N/mm<sup>2</sup>), NIT: 73.0 N/mm<sup>2</sup> (67.0–83.0 N/mm<sup>2</sup>); E<sub>IT</sub> CON: 1999.0 MPa (1952.0–2154.0 MPa); NIT: 2047.0 MPa (1702.0–2104.0 MPa); η<sub>IT</sub> CON: 28.0% (27.2%–29.0%) and NIT: 28.9% (27.1%–31.4%). The results of this study showed that elimination of oxygen during printing does not affect the mechanical properties of 3D printed aligners.</p>","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"133 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143472429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Internal fixation of short bilateral sagittal split osteotomy of the mandibular ramus: A mechanical evaluation 下颌支短双侧矢状劈开截骨内固定:力学评价。
IF 1.8 4区 医学
European Journal of Oral Sciences Pub Date : 2025-02-20 DOI: 10.1111/eos.70006
Nilton Pires de Araújo Filho, Daniel Santiago Vale, Alann Thaffarell Portilho Souza, Alexandre Meireles Borba, Gileade Pereira Freitas, Helena Bacha Lopes
{"title":"Internal fixation of short bilateral sagittal split osteotomy of the mandibular ramus: A mechanical evaluation","authors":"Nilton Pires de Araújo Filho,&nbsp;Daniel Santiago Vale,&nbsp;Alann Thaffarell Portilho Souza,&nbsp;Alexandre Meireles Borba,&nbsp;Gileade Pereira Freitas,&nbsp;Helena Bacha Lopes","doi":"10.1111/eos.70006","DOIUrl":"10.1111/eos.70006","url":null,"abstract":"<p>This study evaluated in vitro three internal fixation methods for short bilateral sagittal split osteotomy (BSSO) of the mandibular ramus using polyurethane replicas. After simulating an 8-mm mandible advancement with a counterclockwise rotation of 6° to the occlusal plane, the short BSSO was fixed bilaterally by using: (i) three linear bicortical screws; (ii) one miniplate with four monocortical screws and one bicortical screw (hybrid system); and (iii) two miniplates with eight monocortical screws. The load was measured on the central incisors or first molars bilaterally at the displacements of 1, 3, 5, and 7 mm. The data were analyzed using one-way analysis of variance (ANOVA) with Tukey's <i>post hoc</i> test. In addition, a linear regression analysis with dummy variables was performed for each combination of displacement and loading point. There were no statistically significant differences in the loads applied to both central incisors and first molars bilaterally among fixation methods at 1-mm displacement. However, the necessary load was larger for the two miniplates method for 3-, 5-, and 7-mm displacements. Considering the biomechanical aspects and the cost benefit related to the fixation materials, using three linear bicortical screws or a hybrid system may be more favorable than employing two miniplates with eight monocortical screws.</p>","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"133 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of biofilm decontamination methods of dental implant surfaces: A systematic review of in vitro studies 牙种植体表面生物膜去污方法的有效性:体外研究的系统综述。
IF 1.8 4区 医学
European Journal of Oral Sciences Pub Date : 2025-02-20 DOI: 10.1111/eos.70005
Faleh Abushahba, Ahmed Algahawi, Nagat Areid, Pekka K. Vallittu, Timo Närhi
{"title":"Efficacy of biofilm decontamination methods of dental implant surfaces: A systematic review of in vitro studies","authors":"Faleh Abushahba,&nbsp;Ahmed Algahawi,&nbsp;Nagat Areid,&nbsp;Pekka K. Vallittu,&nbsp;Timo Närhi","doi":"10.1111/eos.70005","DOIUrl":"10.1111/eos.70005","url":null,"abstract":"<p>This systematic review examines the decontamination techniques used to clean titanium (Ti) implant surfaces covered with in vitro bacterial biofilms. The selected studies were gathered from the PubMed and Web of Science databases. These include in vitro studies investigating decontamination methods used to clean Ti implant surfaces coated with bacterial biofilms until January 2024. The determined studies were filtered according to the PRISMA guidelines, and the Science in Risk Assessment and Policy (SciRAP) was used to assess the reporting and methodological quality of the included studies. A total of 634 full-length peer-reviewed articles were identified. After excluding duplicate papers between the databases and screening according to the predefined inclusion and exclusion criteria, 13 studies were included. The decontamination methods investigated included mechanical, chemical, and physical methods, either as a single or in a combined approach. Significant variability was observed among the included studies. Combining the mechanical and physical methods with a chemical yielded the most significant reduction in both single- and multiple-species biofilms. The current results do not indicate that any single decontamination technique is more effective than others in eradicating bacterial biofilm from Ti surfaces; the combined approach was more advantageous than the single ones.</p>","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"133 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alterations of bone proteins in medication-related osteonecrosis of the jaw 颌骨药物相关性骨坏死中骨蛋白的改变。
IF 1.8 4区 医学
European Journal of Oral Sciences Pub Date : 2025-02-19 DOI: 10.1111/eos.70003
Andrea Schubert, Phillipp Brockmeyer, Philipp Kauffmann, Jan Wiegel, Florian Lautenbacher, Nicolai Miosge, Boris Schminke
{"title":"Alterations of bone proteins in medication-related osteonecrosis of the jaw","authors":"Andrea Schubert,&nbsp;Phillipp Brockmeyer,&nbsp;Philipp Kauffmann,&nbsp;Jan Wiegel,&nbsp;Florian Lautenbacher,&nbsp;Nicolai Miosge,&nbsp;Boris Schminke","doi":"10.1111/eos.70003","DOIUrl":"10.1111/eos.70003","url":null,"abstract":"<p>Changes in the protein expression pattern of osteoblastic lineage cells from the alveolar bone (OLAB) during medication-related osteonecrosis of the jaw (MRONJ) have rarely been investigated. This lack of information is partly because of the limited availability of healthy samples and the lack of human alveolar bone cell lines for research. The aim of the present study was to investigate the bone proteins collagen 1, runt-related transcription factor 2 (RUNX2), and tumor necrosis factor ligand superfamily member 11 (RANKL). Furthermore, we established a cell lineage of OLAB suitable for the analyses of protein expression. We used immunohistochemistry to determine protein expression patterns in vivo. OLAB were treated during culture with zoledronate or denosumab and analyzed by immunocytochemistry and western blotting. Collagen 1 was decreased in vivo in patients with MRONJ and in vitro by denosumab. Zoledronate reduced the level of RUNX2 in vitro. However, RANKL was not significantly affected by zoledronate or denosumab. The results of the present study will help us elucidate the cellular mechanisms of MRONJ. Although culture of OLAB with zoledronate and denosumab significantly altered the protein expression patterns, future research is needed to examine the effects of bone scaffolds, biofilms, and additional cell types mimicking in vivo conditions.</p>","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"133 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eos.70003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect on mechanical and microbiological properties of adding calcium glycerophosphate and xylitol to glass ionomer cement 添加甘油磷酸钙和木糖醇对玻璃离聚体水泥力学和微生物性能的影响。
IF 1.8 4区 医学
European Journal of Oral Sciences Pub Date : 2025-02-13 DOI: 10.1111/eos.70001
Juliana de Azevedo Santana, Maria Fidela de Lima Navarro, Leonardo Fernandes Gomes, Fernanda Lourenção Brighenti, Analú Barros de Oliveira, Gabriela Leal Peres Fernandes, Gabriel Pereira Nunes, Marcelle Danelon
{"title":"Effect on mechanical and microbiological properties of adding calcium glycerophosphate and xylitol to glass ionomer cement","authors":"Juliana de Azevedo Santana,&nbsp;Maria Fidela de Lima Navarro,&nbsp;Leonardo Fernandes Gomes,&nbsp;Fernanda Lourenção Brighenti,&nbsp;Analú Barros de Oliveira,&nbsp;Gabriela Leal Peres Fernandes,&nbsp;Gabriel Pereira Nunes,&nbsp;Marcelle Danelon","doi":"10.1111/eos.70001","DOIUrl":"10.1111/eos.70001","url":null,"abstract":"<p>This study aimed to evaluate the effect on the mechanical and microbiological properties of incorporating calcium glycerophosphate (CaGP) and/or xylitol into resin modified glass ionomer cement (RMGIC). Six experimental cements were tested: i) RMGIC without additions; and RMGIC with ii) 5% xylitol; iii) 10% xylitol; iv) 3% CaGP; v) 3% CaGP and 5% xylitol, or vi) 3% CaGP and 10% xylitol. The compressive strength, diametral tensile strength and surface hardness were determined (24 h and 7 days). Antimicrobial/antibiofilm activity was evaluated. Compressive strength values after 24 h for +3% CaGP &amp; 5% xylitol were higher and similar to RMGIC. After 7 days, +3% CaGP &amp; 5% xylitol presented the highest compressive strength values. The +3% CaGP &amp; 10% xylitol showed the lowest values of diametral tensile strength values (24 h). The RMGIC with +3% CaGP &amp; 5% xylitol showed the highest diametral tensile strength (7 days). The surface hardness (24 h) were highest for the RMGIC and +10% xylitol. After 7 days, +3% CaGP &amp; 5% xylitol showed the highest value. The +3% CaGP &amp; 5% xylitol or +3% CaGP &amp; 10% xylitol showed the lowest levels of microbial/biofilm formation. The addition of CaGP/xylitol promoted improved the mechanical and antibacterial properties of RMGIC.</p>","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"133 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of glucocorticoids on osteocytes and on the lacuno-canalicular system of maxillary and mandibular alveolar bone 糖皮质激素对上颌和下颌牙槽骨骨细胞和腔隙-小管系统的影响。
IF 1.8 4区 医学
European Journal of Oral Sciences Pub Date : 2025-02-10 DOI: 10.1111/eos.70000
Juliana Rodriguez, Mariela Lacave, Luciana Marina Sánchez, Romina Carmen De Lucca, Deborah Ruth Tasat, Carola Bettina Bozal
{"title":"Impact of glucocorticoids on osteocytes and on the lacuno-canalicular system of maxillary and mandibular alveolar bone","authors":"Juliana Rodriguez,&nbsp;Mariela Lacave,&nbsp;Luciana Marina Sánchez,&nbsp;Romina Carmen De Lucca,&nbsp;Deborah Ruth Tasat,&nbsp;Carola Bettina Bozal","doi":"10.1111/eos.70000","DOIUrl":"10.1111/eos.70000","url":null,"abstract":"<p>In long bones, glucocorticoids are known to cause a decrease in bone formation and an increase in bone resorption, leading to a condition of osteoporosis also during growth. However, there are few studies on the effect of glucocorticoids on alveolar bone. The aim of the present study was to evaluate the impact of chronic administration of glucocorticoids on osteocytes and the lacuno-canalicular system of maxillary and mandibular alveolar bone in growing rats. Male Wistar rats were administered intramuscular dexamethasone (7 mg/kg b.w.) or saline solution once a week for 5 weeks. After euthanasia, mandibles and upper maxillae were resected and processed for micro-computed tomography, histological, and immunohistochemical evaluation. Glucocorticoids induced morphological changes in the lacuno-canalicular system and apoptosis of alveolar bone osteocytes and had no effect on SOST/sclerostin osteocyte expression. Our findings suggest that the deleterious effect of glucocorticoids on alveolar bone is associated with osteocyte apoptosis and lacuno-canalicular system changes, whereas Wnt/β catenin pathway regulation in osteocytes appears to play no significant role in the pathogenesis of glucocorticoid-induced bone loss.</p>","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"133 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical efficacy of adjunctive use of coenzyme Q10 in non-surgical periodontal treatment: A systematic review 辅助使用辅酶Q10在牙周非手术治疗中的临床疗效:一项系统综述。
IF 1.8 4区 医学
European Journal of Oral Sciences Pub Date : 2025-02-07 DOI: 10.1111/eos.70002
Matheus dos Santos Fernandez, Thiago Marchi Martins, Jonathan Meza-Mauricio, Mauro Cardoso Ribeiro, Francisco Hecktheuer Silva, Maísa Casarin, Francisco Wilker Mustafa Gomes Muniz
{"title":"Clinical efficacy of adjunctive use of coenzyme Q10 in non-surgical periodontal treatment: A systematic review","authors":"Matheus dos Santos Fernandez,&nbsp;Thiago Marchi Martins,&nbsp;Jonathan Meza-Mauricio,&nbsp;Mauro Cardoso Ribeiro,&nbsp;Francisco Hecktheuer Silva,&nbsp;Maísa Casarin,&nbsp;Francisco Wilker Mustafa Gomes Muniz","doi":"10.1111/eos.70002","DOIUrl":"10.1111/eos.70002","url":null,"abstract":"<p>This systematic review evaluated the effects of coenzyme Q10 (CoQ10) in non-surgical periodontal treatment (PROSPERO: CRD42022311286). Five databases were screened (up to May/2024). It included only randomized controlled trials (RCTs) of subgingival scaling root planing (SRP) with or without adjunct use of the antioxidant CoQ10 in adults with periodontitis. The risk of bias and the certainty of the evidence were assessed. Meta-analyses were conducted to estimate mean differences for probing depth (PD) and clinical attachment level (CAL) between baseline and follow-up. Ten studies were included, of which four administered CoQ10 locally (topical [<i>n</i> = 1]; intra-pocket [<i>n</i> = 3] modalities), and six used oral supplementation. There was no significant effect of local use of CoQ10 on reduction of PD and gain in CAL. Daily oral supplementation (120 mg/day) with CoQ10 resulted in a greater mean reduction of PD by 0.41 mm (95% CI: 0.02–0.80) and a greater mean CAL gain by 0.52 mm (95% CI: 0.26–0.78) than seen in controls. Based on very low certainty of evidence, there was no significant effect of locally delivered Q10 gel on PD/CAL, but daily oral supplementation with CoQ10 resulted in better periodontal health after 12 weeks.</p>","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"133 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143370455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reviewers 2024 评论者2024
IF 1.8 4区 医学
European Journal of Oral Sciences Pub Date : 2025-01-31 DOI: 10.1111/eos.13039
{"title":"Reviewers 2024","authors":"","doi":"10.1111/eos.13039","DOIUrl":"https://doi.org/10.1111/eos.13039","url":null,"abstract":"","PeriodicalId":11983,"journal":{"name":"European Journal of Oral Sciences","volume":"133 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143117950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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