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PMN-MDSC: A Culprit Behind Immunosenescence and Increased Susceptibility to Clostridioides difficile Infection During Aging PMN-MDSC:衰老过程中免疫衰老和对艰难梭菌感染易感性增加的罪魁祸首
IF 10.1 1区 工程技术
Engineering Pub Date : 2024-11-01 DOI: 10.1016/j.eng.2024.06.014
Jianmin Wu , Ming Zhang , Hao Zhang , Mingxuan Sheng , Jiazeng Sun , Fang Wu , Haina Gao , Lishui Chen , Zhili Li , Qiyu Tian , Longjiao Zhu , Bing Fang
{"title":"PMN-MDSC: A Culprit Behind Immunosenescence and Increased Susceptibility to Clostridioides difficile Infection During Aging","authors":"Jianmin Wu ,&nbsp;Ming Zhang ,&nbsp;Hao Zhang ,&nbsp;Mingxuan Sheng ,&nbsp;Jiazeng Sun ,&nbsp;Fang Wu ,&nbsp;Haina Gao ,&nbsp;Lishui Chen ,&nbsp;Zhili Li ,&nbsp;Qiyu Tian ,&nbsp;Longjiao Zhu ,&nbsp;Bing Fang","doi":"10.1016/j.eng.2024.06.014","DOIUrl":"10.1016/j.eng.2024.06.014","url":null,"abstract":"<div><div>Susceptibility to pathogens in the elderly is heightened with age, largely because of immunosenescence. As an immune regulatory organ, bone marrow creates immune cells that move to other organs and tissues through the blood. Despite the significance of this process of this organ, there is limited research on changes in immune cell generation in the bone marrow and their effects on immunosenescence. In this study, the compositions of immune cells in bone marrow from young (three months) and old (24+ months) mice were compared by means of mass cytometry, with further validation obtained through the reanalysis of single-cell RNA sequencing data and cell sorting via flow cytometry. The effects of differential immune cells on immunosenescence in old mice were evaluated using the <em>Clostridium difficile</em> (<em>C. difficile</em>) infection model. Our results showed that aged mice presented with a reduction in bone trabeculae structure, which was accompanied by a notable increase in polymorphonuclear (PMN)-myeloid-derived suppressor cell (MDSC) abundance. Through bulk-seq and reverse transcription quantitative polymerase chain reaction (RT-qPCR) analysis, we identified differential genes associated with the immune response—specifically, the Th17 cell differentiation pathway. Furthermore, the increase in exported PMN-MDSCs to the large intestine resulted in increased gut permeability and inflammatory damage to the colon following <em>C. difficile</em> infection. After clearing the PMN-MDSCs in old mice using the anti-Gr-1 antibody, the symptoms induced by <em>C. difficile</em> were significantly relieved, as evidenced by an inhibited IL-17 pathway in the colon and reduced gut permeability. In conclusion, aging increases the number of PMN-MDSCs in both the generated bone marrow and the outputted intestine, which contributes to susceptibility to <em>C. difficile</em> infection. This study provides a novel target for anti-aging therapy for immunosenescence, which is beneficial for improving immune function in elders.</div></div>","PeriodicalId":11783,"journal":{"name":"Engineering","volume":"42 ","pages":"Pages 59-73"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progress in Organ Bioprinting for Regenerative Medicine 用于再生医学的器官生物打印技术的进展-文章
IF 10.1 1区 工程技术
Engineering Pub Date : 2024-11-01 DOI: 10.1016/j.eng.2024.04.023
Xiang Wang , Di Zhang , Yogendra Pratap Singh , Miji Yeo , Guotao Deng , Jiaqi Lai , Fei Chen , Ibrahim T. Ozbolat , Yin Yu
{"title":"Progress in Organ Bioprinting for Regenerative Medicine","authors":"Xiang Wang ,&nbsp;Di Zhang ,&nbsp;Yogendra Pratap Singh ,&nbsp;Miji Yeo ,&nbsp;Guotao Deng ,&nbsp;Jiaqi Lai ,&nbsp;Fei Chen ,&nbsp;Ibrahim T. Ozbolat ,&nbsp;Yin Yu","doi":"10.1016/j.eng.2024.04.023","DOIUrl":"10.1016/j.eng.2024.04.023","url":null,"abstract":"<div><div>Organ damage or failure arising from injury, disease, and aging poses challenges due to the body’s limited regenerative capabilities. Organ transplantation presents the issues of donor shortages and immune rejection risks, necessitating innovative solutions. The three-dimensional (3D) bioprinting of organs on demand offers promise in tissue engineering and regenerative medicine. In this review, we explore the state-of-the-art bioprinting technologies, with a focus on bioink and cell type selections. We follow with discussions on advances in the bioprinting of solid organs, such as the heart, liver, kidney, and pancreas, highlighting the importance of vascularization and cell integration. Finally, we provide insights into key challenges and future directions in the context of the clinical translation of bioprinted organs and their large-scale production.</div></div>","PeriodicalId":11783,"journal":{"name":"Engineering","volume":"42 ","pages":"Pages 121-142"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141389905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Controllable Histotomy Based on Hierarchical Magnetic Microneedle Array Robots 基于分层磁性微针阵列机器人的可控组织切除术
IF 10.1 1区 工程技术
Engineering Pub Date : 2024-11-01 DOI: 10.1016/j.eng.2024.05.004
Xiaoxuan Zhang , Hanxu Chen , Taiyu Song , Jinglin Wang , Yuanjin Zhao
{"title":"Controllable Histotomy Based on Hierarchical Magnetic Microneedle Array Robots","authors":"Xiaoxuan Zhang ,&nbsp;Hanxu Chen ,&nbsp;Taiyu Song ,&nbsp;Jinglin Wang ,&nbsp;Yuanjin Zhao","doi":"10.1016/j.eng.2024.05.004","DOIUrl":"10.1016/j.eng.2024.05.004","url":null,"abstract":"<div><div>Investigation of patient-derived primary tissues is of great importance in the biomedical field, but recent tissue slicing and cultivation techniques still have difficulties in satisfying clinical requirements. Here, we propose a controllable histotomy strategy that utilizes hierarchical magnetic microneedle array robots to tailor primary tissues and establish the desired high-throughput tissue-on-a-chip. This histotomy is performed using a three-dimensional printed, mortise-tenon-structured slicing device coupled with a magnetic-particle-loaded and pagoda-shaped microneedle array scaffold. Due to the multilayered structure of these microneedles, tissue specimens can be fixed onto the microneedle scaffold via mechanical interlocking, thereby effectively avoiding tissue slipping during the slicing process. Owing to the encapsulation of magnetic microneedle fragments, these tissue pieces can act as magnetically responsive biohybrid microrobots and can be easily manipulated by magnetic fields, facilitating their separation, transportation, and dynamic culture. Using this strategy, we demonstrate that primary pancreatic cancer tissues can be tailored into tiny pieces and cultured in multilayered microfluidic chips for efficient high-throughput drug screening, indicating the promising future of this technique’s application in clinical settings.</div></div>","PeriodicalId":11783,"journal":{"name":"Engineering","volume":"42 ","pages":"Pages 166-174"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141134464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing the Efficiency of Enterprise Shutdowns for Environmental Protection: An Agent-Based Modeling Approach with High Spatial–Temporal Resolution Data 提高企业停产环境保护的效率:基于高时空分辨率数据的代理建模方法
IF 10.1 1区 工程技术
Engineering Pub Date : 2024-11-01 DOI: 10.1016/j.eng.2024.02.006
Qi Zhou , Shen Qu , Miaomiao Liu , Jianxun Yang , Jia Zhou , Yunlei She , Zhouyi Liu , Jun Bi
{"title":"Enhancing the Efficiency of Enterprise Shutdowns for Environmental Protection: An Agent-Based Modeling Approach with High Spatial–Temporal Resolution Data","authors":"Qi Zhou ,&nbsp;Shen Qu ,&nbsp;Miaomiao Liu ,&nbsp;Jianxun Yang ,&nbsp;Jia Zhou ,&nbsp;Yunlei She ,&nbsp;Zhouyi Liu ,&nbsp;Jun Bi","doi":"10.1016/j.eng.2024.02.006","DOIUrl":"10.1016/j.eng.2024.02.006","url":null,"abstract":"<div><div>Top-down environmental policies aim to mitigate environmental risks but inevitably lead to economic losses due to the market entry or exit of enterprises. This study developed a universal dynamic agent-based supply chain model to achieve tradeoffs between environmental risk reduction and economic sustainability. The model was used to conduct high-resolution daily simulations of the dynamic shifts in enterprise operations and their cascading effects on supply chain networks. It includes production, consumption, and transportation agents, attributing economic features to supply chain components and capturing their interactions. It also accounts for adaptive responses to daily external shocks and replicates realistic firm behaviors. By coupling high spatial–temporal resolution firm-level data from 18 916 chemical enterprises, this study investigates the economic and environmental impacts of an environmental policy resulting in the closure of 1800 chemical enterprises over three years. The results revealed a significant economic loss of 25.8 billion USD, ranging from 23.8 billion to 31.8 billion USD. Notably, over 80% of this loss was attributed to supply chain propagation. Counterfactual analyses indicated that implementing a staggered shutdown strategy prevented 18.8% of supply chain losses, highlighting the importance of a gradual policy implementation to prevent abrupt supply chain disruptions. Furthermore, the study highlights the effectiveness of a multi-objective policy design in reducing economic losses (about 29%) and environmental risks (about 40%), substantially enhancing the efficiency of the environmental policy. The high-resolution simulations provide valuable insights for policy designers to formulate strategies with staggered implementation and multiple objectives to mitigate supply chain losses and environmental risks and ensure a sustainable future.</div></div>","PeriodicalId":11783,"journal":{"name":"Engineering","volume":"42 ","pages":"Pages 295-307"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140129288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis and Zonation of Freeze–Thaw Action in the Chinese Plateau Region Considering Spatiotemporal Climate Characteristics 考虑时空气候特征的中国高原地区冻融作用分析与区划
IF 10.1 1区 工程技术
Engineering Pub Date : 2024-11-01 DOI: 10.1016/j.eng.2024.04.016
Tiejun Liu , Ming Zhang , Dujian Zou , Jiaping Liu , Jinping Ou
{"title":"Analysis and Zonation of Freeze–Thaw Action in the Chinese Plateau Region Considering Spatiotemporal Climate Characteristics","authors":"Tiejun Liu ,&nbsp;Ming Zhang ,&nbsp;Dujian Zou ,&nbsp;Jiaping Liu ,&nbsp;Jinping Ou","doi":"10.1016/j.eng.2024.04.016","DOIUrl":"10.1016/j.eng.2024.04.016","url":null,"abstract":"<div><div>Concerns about the durability of transportation infrastructure due to freeze–thaw (F–T) cycles are particularly significant in the Chinese plateau region, where concrete aging and performance deterioration pose substantial challenges. The current national standards for the frost resistance design of concrete structures are based predominantly on the coldest monthly average temperature and do not adequately address the comprehensive effects of the spatiotemporal variance, amplitude, and frequency of F–T cycles. To address this issue, this study introduced a spatiotemporal distribution model to analyze the long-term impact of F–T action on concrete structures by employing statistical analysis and spatial interpolation techniques. Cluster analysis was applied to create a nationwide zonation of F–T action level from data on the freezing temperature, temperature difference, and the number of F–T cycles. Furthermore, this study explored the similarity between natural environmental conditions and laboratory-accelerated tests using hydraulic pressure and cumulative damage theories. A visualization platform that incorporates tools for meteorological data queries, environmental characteristic analyses, and F–T action similarity calculations was designed. This research lays theoretical groundwork and provides technical guidance for assessing service life and enhancing the quantitative durability design of concrete structures in the Chinese plateau region.</div></div>","PeriodicalId":11783,"journal":{"name":"Engineering","volume":"42 ","pages":"Pages 308-325"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141054807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Regeneration of Intestinal Stem Cells Is Driven by miR-29-Induced Metabolic Reprogramming 肠干细胞的再生是由 miR-29 诱导的代谢重编程驱动的
IF 10.1 1区 工程技术
Engineering Pub Date : 2024-11-01 DOI: 10.1016/j.eng.2024.08.008
Yingying Lin , Yao Lu , Yuqi Wang , Cong Lv , Juan Chen , Yongting Luo , Heng Quan , Weiru Yu , Lining Chen , Ziyu Huang , Yanling Hao , Qingyu Wang , Qingfeng Luo , Jingyu Yan , Yixuan Li , Wei Zhang , Min Du , Jian He , Fazheng Ren , Huiyuan Guo
{"title":"The Regeneration of Intestinal Stem Cells Is Driven by miR-29-Induced Metabolic Reprogramming","authors":"Yingying Lin ,&nbsp;Yao Lu ,&nbsp;Yuqi Wang ,&nbsp;Cong Lv ,&nbsp;Juan Chen ,&nbsp;Yongting Luo ,&nbsp;Heng Quan ,&nbsp;Weiru Yu ,&nbsp;Lining Chen ,&nbsp;Ziyu Huang ,&nbsp;Yanling Hao ,&nbsp;Qingyu Wang ,&nbsp;Qingfeng Luo ,&nbsp;Jingyu Yan ,&nbsp;Yixuan Li ,&nbsp;Wei Zhang ,&nbsp;Min Du ,&nbsp;Jian He ,&nbsp;Fazheng Ren ,&nbsp;Huiyuan Guo","doi":"10.1016/j.eng.2024.08.008","DOIUrl":"10.1016/j.eng.2024.08.008","url":null,"abstract":"<div><div>Intestinal stem cells (ISCs) initiate intestinal epithelial regeneration and tumorigenesis, and they experience rapid refilling upon various injuries for epithelial repair as well as tumor reoccurrence. It is crucial to reveal the mechanism underlying such plasticity for intestinal health. Recent studies have found that metabolic pathways control stem cell fate in homeostasis, but the role of metabolism in the regeneration of ISCs after damage has not been clarified. Here, we find that in a human colorectal cancer dataset, miR-29a and b (miR-29a/b) are metabolic regulators highly associated with intestinal tumorigenesis and worse prognostic value of radiotherapy. We also show that these two microRNAs are required for intestinal stemness maintenance in mice, and their expression is induced in regenerated ISCs after irradiation injury, resulting in skewed ISC fate from differentiation towards self-renewal. This upregulation of miR-29a/b expression in ISCs leads to suppression of fatty acid oxidation (FAO) and depression of oxidative phosphorylation, which in turn controls the balance between self-renewal and differentiation of ISCs. Deletion of miR-29a/b prevents these effects and thus impairs ISC-mediated epithelial recovery. Finally, we filter the potential targets of miR-29a/b and identify <em>Hnf4g</em>, a transcription factor, that drives this metabolic reprogramming through regulating FAO-related enzymes. Our work discovers an important metabolic mechanism of ISC-mediated regeneration and potentially pave the way for more targeted and effective therapeutic strategies for intestinal repair as well as tumor treatment.</div></div>","PeriodicalId":11783,"journal":{"name":"Engineering","volume":"42 ","pages":"Pages 39-58"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142701432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rotational Intravascular Multidirectional Ultrasound Catheter for Sonothrombolysis of Retracted Clots: An in Vitro and in Vivo Study 旋转式血管内多方位超声导管用于声波溶栓:体外和体内研究
IF 10.1 1区 工程技术
Engineering Pub Date : 2024-11-01 DOI: 10.1016/j.eng.2024.03.021
Huaiyu Wu , Jinwook Kim , Bohua Zhang , Gabe Owens , Greyson Stocker , Mengyue Chen , Benjamin C. Kreager , Ashley Cornett , Kathlyne Bautista , Tarana Kaovasia , Paul A. Dayton , Zhen Xu , Xiaoning Jiang
{"title":"Rotational Intravascular Multidirectional Ultrasound Catheter for Sonothrombolysis of Retracted Clots: An in Vitro and in Vivo Study","authors":"Huaiyu Wu ,&nbsp;Jinwook Kim ,&nbsp;Bohua Zhang ,&nbsp;Gabe Owens ,&nbsp;Greyson Stocker ,&nbsp;Mengyue Chen ,&nbsp;Benjamin C. Kreager ,&nbsp;Ashley Cornett ,&nbsp;Kathlyne Bautista ,&nbsp;Tarana Kaovasia ,&nbsp;Paul A. Dayton ,&nbsp;Zhen Xu ,&nbsp;Xiaoning Jiang","doi":"10.1016/j.eng.2024.03.021","DOIUrl":"10.1016/j.eng.2024.03.021","url":null,"abstract":"<div><div>Thromboembolism in blood vessels poses a serious risk of stroke, heart attack, and even sudden death if not properly managed. Sonothrombolysis combined with ultrasound contrast agents has emerged as a promising approach for the effective treatment of thromboembolism. Recent reports have highlighted the potential of intravascular sonothrombolysis as a safe and effective treatment modality for deep vein thrombosis (DVT). However, its efficiency has not been validated through <em>in vivo</em> testing of retracted clots. This study aimed to develop a miniaturized multidirectional transducer featuring two 4-layer lead zirconate titanate (PZT-5A) stacks with an aperture size of 1.4 mm × 1.4 mm, enabling both forward- and side-looking treatment. Integrated into a custom two-lumen 10-French (Fr) catheter, the capability of this device for intravascular sonothrombolysis was validated both <em>in vitro</em> and <em>in vivo</em>. With low-dose tissue plasminogen activators and nanodroplets, the rotational multidirectional transducer reduced the retracted clot mass (800 mg) by an average of 52% within 30 min during <em>in vitro</em> testing. The lysis rate was significantly higher by 37% than that in a forward-viewing transducer without rotation. This improvement was particularly noteworthy in the treatment of retracted clots. Notably, a long-retracted clot (&gt; 10 cm) was successfully treated within 40 min <em>in vivo</em> by creating a flow channel with a diameter &gt; 4 mm in a porcine DVT model. In conclusion, these findings strongly suggest the potential of this technique for clinical applications in sonothrombolysis, offering a feasible solution for effectively treating thromboembolism, particularly in challenging cases involving retracted clots.</div></div>","PeriodicalId":11783,"journal":{"name":"Engineering","volume":"42 ","pages":"Pages 235-243"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Landslide Damming Threats Along the Jinsha River, China 中国金沙江沿岸的滑坡筑坝威胁
IF 10.1 1区 工程技术
Engineering Pub Date : 2024-11-01 DOI: 10.1016/j.eng.2024.07.001
Shihao Xiao , Limin Zhang , Te Xiao , Ruochen Jiang , Dalei Peng , Wenjun Lu , Xin He
{"title":"Landslide Damming Threats Along the Jinsha River, China","authors":"Shihao Xiao ,&nbsp;Limin Zhang ,&nbsp;Te Xiao ,&nbsp;Ruochen Jiang ,&nbsp;Dalei Peng ,&nbsp;Wenjun Lu ,&nbsp;Xin He","doi":"10.1016/j.eng.2024.07.001","DOIUrl":"10.1016/j.eng.2024.07.001","url":null,"abstract":"<div><div>The 2280 km long Jinsha River has been blocked at least four times in the past 30 years. A landslide damming hazard chain can endanger communities and infrastructures hundreds of kilometers downstream from the damming site in alpine gorges. Past damming events have resulted in severe consequences, demanding a thorough assessment of damming threats along the entire Jinsha River. This study digitizes the Jinsha River and visualizes its topographic, tectonic, hydrologic, and climate characteristics in detail. A two-stage full-probability method is proposed for assessing the damming threats along this river, making it possible to identify potential damming hotspots and high-priority zones for hazard mitigation. It is found that the upper reach of the Jinsha River poses the greatest damming threat, and the threat level gradually decreases downstream. Approximately 33.4%, 36.7%, 20.5%, and 9.4% of the entire length of the Jinsha River are classified as low, moderate, high, and very high threat levels, respectively. Compared with existing hydropower projects, future projects in the upper reach are more likely to be exposed to landslide damming. We highlight the value of basin-scale spatial threat analysis and envisage that our findings will promote more targeted local-scale risk assessments for potential damming hotspots. These outcomes provide the basis for managing the risks of river damming and hydropower infrastructure along the Jinsha River.</div></div>","PeriodicalId":11783,"journal":{"name":"Engineering","volume":"42 ","pages":"Pages 326-339"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141841738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Integrated Anti-Fouling and Anti-Corrosion Coating Enabled by rGO/AgNPs and Amphiphilic Networks 由 rGO/AgNPs 和两性网络实现的防污和防腐蚀一体化涂层
IF 10.1 1区 工程技术
Engineering Pub Date : 2024-11-01 DOI: 10.1016/j.eng.2022.09.019
Shu Tian , Jinli Zhang , Shuan Liu , Jingyu Li , Jibin Pu , Yugang Hao , Guobing Ying , Qunji Xue , Guangming Lu
{"title":"An Integrated Anti-Fouling and Anti-Corrosion Coating Enabled by rGO/AgNPs and Amphiphilic Networks","authors":"Shu Tian ,&nbsp;Jinli Zhang ,&nbsp;Shuan Liu ,&nbsp;Jingyu Li ,&nbsp;Jibin Pu ,&nbsp;Yugang Hao ,&nbsp;Guobing Ying ,&nbsp;Qunji Xue ,&nbsp;Guangming Lu","doi":"10.1016/j.eng.2022.09.019","DOIUrl":"10.1016/j.eng.2022.09.019","url":null,"abstract":"<div><div>Marine corrosion and biofouling are challenges that affect marine industrial equipment, and protecting equipment with functional coatings is a simple and effective approach. However, it is extremely difficult to combine anti-corrosion and anti-fouling properties in a single coating. In this work, we combine reduced graphene oxide (rGO)/silver nanoparticles (AgNPs) with a hydrophilic polymer in a bio-based silicone–epoxy resin to create a coating with both anti-fouling and anti-corrosion properties. The excellent anti-fouling performance of the coating results from a ternary synergistic mechanism involving fouling release, contact inhibition, and a hydration effect, while the outstanding anti-corrosion performance is provided by a ternary synergistic anti-corrosion mechanism that includes a dense interpenetrating network (IPN) structure, a barrier effect, and passivation. The results show that the obtained coating possesses superior anti-fouling activity against protein, bacteria, algae, and other marine organisms, as well as excellent anti-corrosion and certain self-healing properties due to its dynamic cross-linked network of rGO/AgNPs and the hydrophilic polymer. This work provides an anti-corrosion and anti-fouling integrated coating for marine industrial equipment.</div></div>","PeriodicalId":11783,"journal":{"name":"Engineering","volume":"42 ","pages":"Pages 223-234"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robust, Flexible, and Superhydrophobic Fabrics for High-Efficiency and Ultrawide-Band Microwave Absorption 用于高效和超宽带微波吸收的坚固、柔韧和超疏水织物
IF 10.1 1区 工程技术
Engineering Pub Date : 2024-10-01 DOI: 10.1016/j.eng.2024.03.009
{"title":"Robust, Flexible, and Superhydrophobic Fabrics for High-Efficiency and Ultrawide-Band Microwave Absorption","authors":"","doi":"10.1016/j.eng.2024.03.009","DOIUrl":"10.1016/j.eng.2024.03.009","url":null,"abstract":"<div><div>Microwave absorption (MA) materials are essential for protecting against harmful electromagnetic radiation. In this study, highly efficient and ultrawide-band microwave-absorbing fabrics with superhydrophobic surface features were developed using a facile dip-coating method involving <em>in situ</em> graphene oxide (GO) reduction, deposition of TiO<sub>2</sub> nanoparticles, and subsequent coating of a mixture of polydimethylsiloxane (PDMS) and octadecylamine (ODA) on polyester fabrics. Owing to the presence of hierarchically structured surfaces and low-surface-energy materials, the resultant reduced GO (rGO)/TiO<sub>2</sub>-ODA/PDMS-coated fabrics demonstrate superhydrophobicity with a water contact angle of 159° and sliding angle of 5°. Under the synergistic effects of conduction loss, interface polarization loss, and surface roughness topography, the optimized fabrics show excellent microwave absorbing performances with a minimum reflection loss (RL<sub>min</sub>) of −47.4 dB and a maximum effective absorption bandwidth (EAB<sub>max</sub>) of 7.7 GHz at a small rGO loading of 6.9 wt%. In addition, the rGO/TiO<sub>2</sub>-ODA/PDMS coating was robust, and the coated fabrics could withstand repeated washing, soiling, long-term ultraviolet irradiation, and chemical attacks without losing their superhydrophobicity and MA properties. Moreover, the coating imparts self-healing properties to the fabrics. This study provides a promising and effective route for the development of robust and flexible materials with microwave-absorbing properties.</div></div>","PeriodicalId":11783,"journal":{"name":"Engineering","volume":"41 ","pages":"Pages 161-171"},"PeriodicalIF":10.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140788958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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