{"title":"RETRACTION: Prognostic Impact of Lactylation-Associated Gene Modifications in Clear Cell Renal Cell Carcinoma: Insights into Molecular Landscape and Therapeutic Opportunities","authors":"","doi":"10.1002/tox.24530","DOIUrl":"10.1002/tox.24530","url":null,"abstract":"<p>\u0000 \u0000 <b>RETRACTION:</b> <span>J. Liu</span>, <span>P. Chen</span>, <span>J. Zhou</span>, <span>H. Li</span>, and <span>Z. Pan</span>, “ <span>Prognostic Impact of Lactylation-Associated Gene Modifications in Clear Cell Renal Cell Carcinoma: Insights into Molecular Landscape and Therapeutic Opportunities</span>,” <i>Environmental Toxicology</i> <span>39</span>, no. <span>3</span> (<span>2024</span>): <span>1360</span>–<span>1373</span>, https://doi.org/10.1002/tox.24040.\u0000 </p><p>The above article, published online on 16 November 2023 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted. The authors were notified of this decision but did not respond.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"40 8","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tox.24530","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143930778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RETRACTION: Single-Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in Lung Adenocarcinoma","authors":"","doi":"10.1002/tox.24531","DOIUrl":"10.1002/tox.24531","url":null,"abstract":"<p>\u0000 \u0000 <b>RETRACTION:</b> <span>H. Xu</span>, <span>L. Jiang</span>, <span>L. Qin</span>, <span>P. Shi</span>, <span>P. Xu</span>, and <span>C. Liu</span>, “ <span>Single-Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in Lung Adenocarcinoma</span>,” <i>Environmental Toxicology</i> <span>39</span>, no. <span>3</span> (<span>2024</span>): <span>1847</span>–<span>1857</span>, https://doi.org/10.1002/tox.24048.\u0000 </p><p>The above article, published online on 22 December 2023 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted. The authors were notified of this decision but did not respond.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"40 8","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tox.24531","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143930779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ji-Hye Ha, Ba-Wool Lee, Da-Hye Yi, Seong-Hun Jeong, Ju-Hong Kim, Hyun-Jae Jang, Ju Hwan Jeong, Ji-Young Park, Hyung Jae Jeong, Hyung-Jun Kwon, Young-Bae Ryu, In-Chul Lee
{"title":"Dendranthema oreastrum (Hance) Y.Ling Attenuates Oxidative Stress and Airway Inflammation in a Murine Model of Lipopolysaccharide-Induced Acute Lung Injury","authors":"Ji-Hye Ha, Ba-Wool Lee, Da-Hye Yi, Seong-Hun Jeong, Ju-Hong Kim, Hyun-Jae Jang, Ju Hwan Jeong, Ji-Young Park, Hyung Jae Jeong, Hyung-Jun Kwon, Young-Bae Ryu, In-Chul Lee","doi":"10.1002/tox.24520","DOIUrl":"10.1002/tox.24520","url":null,"abstract":"<p>We examined the antioxidant and anti-inflammatory effects of the methanolic extract of <i>Dendranthema oreastrum</i> (Hance) Y.Ling, commonly known as “Gu-Jeol-Cho” in Korea and widely found across East Asia, using an LPS-induced acute lung injury (ALI) mouse model and TNF-α-stimulated NCI-H292 cells. LPS was intratracheally administered at 20 μg/50 μL/mouse for 3 days. From test day 1 to 5, experimental mice were administered DO (100 and 200 mg/kg/day) or dexamethasone (3 mg/kg/day). DO treatment decreased pro-inflammatory cytokines in bronchoalveolar lavage fluid and TNF-α-stimulated NCI-H292 cells. Additionally, DO treatment decreased alveolar wall thickening and inflammatory cell infiltration in lung tissues. DO down-regulated TXNIP expression, inhibiting NF-κB activation. Furthermore, DO administration reduced NLRP3 inflammasome activity by preventing the activation of caspase-1 and IL-1β. Additionally, DO promoted the nuclear translocation of Nrf2-related factors, leading to an upregulation of antioxidant enzymes. The study demonstrated that DO administration markedly decreased reactive oxygen species and lipid peroxidation. These observations indicate that DO is a therapeutic agent for ALI.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"40 10","pages":"1220-1232"},"PeriodicalIF":3.2,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tox.24520","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143866857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RETRACTION: FOXA2 Suppresses Gallbladder Carcinoma Cell Migration, Invasion, and Epithelial-Mesenchymal Transition by Targeting SERPINB5","authors":"","doi":"10.1002/tox.24522","DOIUrl":"10.1002/tox.24522","url":null,"abstract":"<p>\u0000 \u0000 <b>RETRACTION</b>: <span>L. Hong</span>, <span>M. Chen</span>, <span>M. Huang</span>, <span>W. Chen</span>, <span>X. Abudukeremu</span>, <span>F. She</span>, and <span>Y. Chen</span>, “ <span>FOXA2 Suppresses Gallbladder Carcinoma Cell Migration, Invasion, and Epithelial-Mesenchymal Transition by Targeting SERPINB5</span>,” <i>Environmental Toxicology</i> <span>39</span>, no. <span>2</span> (<span>2024</span>): <span>708</span>–<span>722</span>, https://doi.org/10.1002/tox.23953.\u0000 </p><p>The above article, published online on 4 September 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted. The authors have been informed of this decision.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"40 8","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tox.24522","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143862454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RETRACTION: Eosinophils and Risk of Ulcerative Colitis in European Population: Evidence from Mendelian Randomization Study","authors":"","doi":"10.1002/tox.24526","DOIUrl":"10.1002/tox.24526","url":null,"abstract":"<p>\u0000 \u0000 <b>RETRACTION</b>: <span>Y. Shao</span>, <span>C. Liu</span>, <span>X. Wang</span>, and <span>W. Zhu</span>, “ <span>Eosinophils and Risk of Ulcerative Colitis in European Population: Evidence from Mendelian Randomization Study</span>,” <i>Environmental Toxicology</i> <span>39</span>, no. <span>10</span> (<span>2024</span>): <span>4669</span>–<span>4676</span>, https://doi.org/10.1002/tox.24314.\u0000 </p><p>The above article, published online on 29 April 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted. The authors have been informed of this decision.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"40 8","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tox.24526","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143862474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RETRACTION: Elucidating the Molecular Mechanisms of Sepsis: Identifying Key Aging-Related Biomarkers and Potential Therapeutic Targets in the Treatment of Sepsis","authors":"","doi":"10.1002/tox.24524","DOIUrl":"10.1002/tox.24524","url":null,"abstract":"<p>\u0000 \u0000 <b>RETRACTION:</b> <span>J. Zhou</span>, <span>J. Liu</span>, <span>C. Zhang</span>, <span>Y. Zhou</span>, <span>Z. Zheng</span>, and <span>H. Li</span>, “ <span>Elucidating the Molecular Mechanisms of Sepsis: Identifying Key Aging-Related Biomarkers and Potential Therapeutic Targets in the Treatment of Sepsis</span>,” <i>Environmental Toxicology</i> <span>39</span>, no. <span>6</span> (<span>2024</span>): <span>3341</span>–<span>3355</span>, https://doi.org/10.1002/tox.24198.\u0000 </p><p>The above article, published online on 5 March 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted. The authors have been informed of this decision.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"40 8","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tox.24524","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143862455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RETRACTION: Integrated Analysis of Gut Microbiota and Metabolomic Profiling in Colorectal Cancer Metastasis","authors":"","doi":"10.1002/tox.24525","DOIUrl":"10.1002/tox.24525","url":null,"abstract":"<p>\u0000 \u0000 <b>RETRACTION</b>: <span>Y. Xia</span>, <span>L. Duan</span>, <span>X.L. Zhang</span>, <span>Y.J. Niu</span>, and <span>X. Ling</span>, “ <span>Integrated Analysis of Gut Microbiota and Metabolomic Profiling in Colorectal Cancer Metastasis</span>,” <i>Environmental Toxicology</i> <span>39</span>, no. <span>10</span> (<span>2024</span>): <span>4467</span>–<span>4478</span>, https://doi.org/10.1002/tox.24228.\u0000 </p><p>The above article, published online on 14 March 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, Christyn Bailey; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"40 7","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tox.24525","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143862046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RETRACTION: Value of Hepatic Artery Digital Subtraction Angiography in the Detection of Small Hepatocellular Carcinoma Lesions","authors":"","doi":"10.1002/tox.24527","DOIUrl":"10.1002/tox.24527","url":null,"abstract":"<p>\u0000 \u0000 <b>RETRACTION</b>: <span>T. Bai</span>, <span>S. Lu</span>, <span>J. Chen</span>, <span>J. Ye</span>, <span>X. Wang</span>, <span>Z. Tang</span>, <span>H. Fu</span>, <span>L. Li</span>, and <span>F. Wu</span>, “ <span>Value of Hepatic Artery Digital Subtraction Angiography in the Detection of Small Hepatocellular Carcinoma Lesions</span>,” <i>Environmental Toxicology</i> <span>39</span>, no. <span>10</span> (<span>2024</span>): <span>4754</span>–<span>4762</span>, https://doi.org/10.1002/tox.24316.\u0000 </p><p>The above article, published online on 20 August 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted. The authors disagree with this decision.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"40 7","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tox.24527","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143862426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RETRACTION: Exosomal miRNA-166-5p Derived from G-MDSCs Promotes Proliferation by Targeting ITM3E in Colorectal Cancer","authors":"","doi":"10.1002/tox.24523","DOIUrl":"10.1002/tox.24523","url":null,"abstract":"<p>\u0000 \u0000 <b>RETRACTION</b>: <span>T. Ma</span>, <span>J. Jiang</span>, <span>M. Shi</span>, and <span>H. Xu</span>, “ <span>Exosomal miRNA-166-5p Derived from G-MDSCs Promotes Proliferation by Targeting ITM3E in Colorectal Cancer</span>,” <i>Environmental Toxicology</i> <span>39</span>, no. <span>2</span> (<span>2024</span>): <span>803</span>–<span>814</span>, https://doi.org/10.1002/tox.23980.\u0000 </p><p>The above article, published online on 4 October 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), and its correction, has been retracted by agreement between the journal Editor-in-Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Additionally, no ethical approval was provided for the human studies portion. Therefore, the article must be retracted. The authors agree with this decision.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"40 8","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tox.24523","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143862464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RETRACTION: Scoparone Inhibits the Development of Hepatocellular Carcinoma by Modulating the p38 MAPK/Akt/NF-κB Signaling in Nonalcoholic Fatty Liver Disease Mice","authors":"","doi":"10.1002/tox.24521","DOIUrl":"10.1002/tox.24521","url":null,"abstract":"<p>\u0000 \u0000 <b>RETRACTION</b>: <span>M. Ye</span>, <span>C. Liu</span>, <span>J. Liu</span>, <span>F. Lu</span>, <span>J. Xue</span>, <span>F. Li</span>, and <span>Y. Tang</span>, “ <span>Scoparone Inhibits the Development of Hepatocellular Carcinoma by Modulating the p38 MAPK/Akt/NF-κB Signaling in Nonalcoholic Fatty Liver Disease Mice</span>,” <i>Environmental Toxicology</i> <span>39</span>, no. <span>2</span> (<span>2024</span>): <span>551</span>–<span>561</span>, https://doi.org/10.1002/tox.23851.\u0000 </p><p>The above article, published online on 12 July 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted. The authors have been informed of this decision.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"40 8","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tox.24521","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143862420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}