Environmental Toxicology最新文献_第7页

RETRACTION: Efficacy of Three-Dimensional Arterial Spin Labeling and How it Compares Against That of Contrast Enhanced Magnetic Resonance Imaging in Preoperative Grading of Brain Gliomas 回放：三维动脉自旋标记的疗效及其与对比增强磁共振成像在脑胶质瘤术前分级中的比较

IF 4.4 3区医学

Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24452

{"title":"RETRACTION: Efficacy of Three-Dimensional Arterial Spin Labeling and How it Compares Against That of Contrast Enhanced Magnetic Resonance Imaging in Preoperative Grading of Brain Gliomas","authors":"","doi":"10.1002/tox.24452","DOIUrl":"10.1002/tox.24452","url":null,"abstract":"\u0000 \u0000 RETRACTION: K. Wang, H. Guo, X. Tian, Y. Miao, P. Han, and F. Jin, “ Efficacy of Three-Dimensional Arterial Spin Labeling and How it Compares Against That of Contrast Enhanced Magnetic Resonance Imaging in Preoperative Grading of Brain Gliomas,” Environmental Toxicology 38, no. 7 (2023): 1723–1731, https://doi.org/10.1002/tox.23800.\u0000 The above article, published online on 11 April 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, Paul B. Tchounwou; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted. The author Feng Jin disagrees with this decision. The other authors did not respond.","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"40 3","pages":"497"},"PeriodicalIF":4.4,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tox.24452","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142697032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RETRACTION: Phenylacetyl Glutamine (PAGln) Enhances Cardiomyocyte Death After Myocardial Infarction Through β1 Adrenergic Receptor 回放：苯乙酰谷氨酰胺（PAGln）通过β1肾上腺素能受体增强心肌梗死后心肌细胞的死亡。

IF 4.4 3区医学

Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24454

{"title":"RETRACTION: Phenylacetyl Glutamine (PAGln) Enhances Cardiomyocyte Death After Myocardial Infarction Through β1 Adrenergic Receptor","authors":"","doi":"10.1002/tox.24454","DOIUrl":"10.1002/tox.24454","url":null,"abstract":"\u0000 \u0000 RETRACTION: H. Xu, N. Yang, B.Y. Wang, L. Zhou, L.L. Xu, Y. Chen, D.J. Wang, and W.H. Ge, “ Phenylacetyl Glutamine (PAGln) Enhances Cardiomyocyte Death after Myocardial Infarction through β1 Adrenergic Receptor,” Environmental Toxicology 39, no. 3 (2024): 1682–1699, https://doi.org/10.1002/tox.24063.\u0000 The above article, published online on 02 December 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, Paul B. Tchounwou; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. In addition, the investigation found there was significant unattributed textual overlap between this article and a previously-published article (Beale et al., 2008; https://doi.org/10.1186/1471-2407-8-200). Therefore, the article must be retracted. The authors Weihong Ge and Hang Xu disagree with this decision. The other authors did not respond.","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"40 3","pages":"499"},"PeriodicalIF":4.4,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tox.24454","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RETRACTION: Neurological Risks Arising From the Bioaccumulation of Heavy Metal Contaminants: A Focus on Mercury 回放：重金属污染物的生物累积对神经系统造成的风险：聚焦汞。

IF 4.4 3区医学

Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24450

引用次数: 0

RETRACTION: Exploring the Role of Lactylation-Related Genes in Osteosarcoma: A Deep Dive Into Prognostic Significance and Therapeutic Potential 回放：探索乳化相关基因在骨肉瘤中的作用：深入探讨预后意义和治疗潜力。

IF 4.4 3区医学

Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24449

引用次数: 0

RETRACTION: Development of the ARDS-Derived Gene Panel for Lung Adenocarcinoma Prognosis Stratification and Experiment Validation of CCL20 Expression. RETRACTION：开发用于肺腺癌预后分层的 ARDS 衍生基因面板，并对 CCL20 表达进行实验验证。

IF 4.4 3区医学

Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24456

引用次数: 0

RETRACTION: Prognostic Value and Potential Mechanism of Cellular Senescence and Tumor Microenvironment in Hepatocellular Carcinoma: Insights From Bulk Transcriptomics and Single-Cell Sequencing Analysis 回放：肝细胞癌中细胞衰老和肿瘤微环境的预后价值和潜在机制：大宗转录组学和单细胞测序分析的启示

IF 4.4 3区医学

Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24453

引用次数: 0

RETRACTION: DPM2 Serve as Novel Oncogene and Prognostic Marker Transactivated by ESR1 in Breast Cancer 返回：DPM2 是由 ESR1 在乳腺癌中反式激活的新型癌基因和预后标志物。

IF 4.4 3区医学

Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24451

引用次数: 0

RETRACTION: Exploring the Tumor Microenvironment: Chemokine-Related Genes and Immunotherapy/Chemotherapy Response in Clear-Cell Renal Cell Carcinoma RETRACTION：探索肿瘤微环境：化疗因子相关基因与透明细胞肾细胞癌的免疫疗法/化疗反应。

IF 4.4 3区医学

Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24455

引用次数: 0

RETRACTION: Circular Forms of Dedicator of Cytokinesis 1 Promotes Breast Cancer Progression by Derepressing Never in Mitosis Related Kinase 2 via Sponging miR-128-3p 回放：细胞分裂驱动因子 1 的环状形式通过海绵状 miR-128-3p 解除对有丝分裂相关激酶 2 的抑制，从而促进乳腺癌的进展。

IF 4.4 3区医学

Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24448

引用次数: 0

Aglaia elliptifolia Leaf Extract Inhibits Autophagy‐Related 4B Protease and Suppresses Malignancies of Colorectal Cancer Cells 椭圆木叶提取物能抑制自噬相关 4B 蛋白酶并抑制结直肠癌细胞恶变

IF 4.5 3区医学

Environmental Toxicology Pub Date : 2024-11-23 DOI: 10.1002/tox.24439

Jing‐Ru Weng, Chih‐Wen Shu, Chia‐Che Chang, Ya‐Chun Wu, Hsiu‐Chen Yang, Cheng‐Hsin Lee, Hans‐Uwe Dahms, Wei‐Yu Lin, Chun‐Lin Chen, Pei‐Feng Liu

{"title":"Aglaia elliptifolia Leaf Extract Inhibits Autophagy‐Related 4B Protease and Suppresses Malignancies of Colorectal Cancer Cells","authors":"Jing‐Ru Weng, Chih‐Wen Shu, Chia‐Che Chang, Ya‐Chun Wu, Hsiu‐Chen Yang, Cheng‐Hsin Lee, Hans‐Uwe Dahms, Wei‐Yu Lin, Chun‐Lin Chen, Pei‐Feng Liu","doi":"10.1002/tox.24439","DOIUrl":"https://doi.org/10.1002/tox.24439","url":null,"abstract":"Autophagy is a self‐eating pathway for maintaining normal cellular physiology, while dysregulation of autophagy is associated with cancer progression. Autophagy‐related 4B gene (ATG4B) is a cysteine protease to regulate autophagosome formation and is positively correlated with poor prognosis of colorectal cancer (CRC) patients. An increasing number of reports have implied that ATG4B might be an attractive drug target for CRC. Natural products are the most important source of drug development for cancer therapy due to their high degree of diversity in chemical structure. However, there are few natural products targeting autophagy regulation, especially targeting ATG4B. We aim to identify effective natural compounds from costal plants against ATG4B as potential CRC therapies. We extracted the whole plants, stem, and leaves from nine coastal plant species of Taiwan using different solvents including acetone, methanol, or chloroform. We then evaluated their effects on ATG4B activity and cancer malignancy in CRC cells (DLD‐1, HCT116, and SW620). Among these 26 extracts, we found that the methanol leaf extract of A. elliptifolia significantly inhibited ATG4B proteolytic activity. Moreover, cell viability and colony formation and mobility were decreased in CRC cells treated with the extract. The extract further reduced the number of living cells and induced subG1 proportion of CRC cells. The cytotoxicity of A. elliptifolia leaf extract was also enhanced in CRC cells under starvation, whereas it had no additional effects in ATG4B or autophagy deficient cells. Taken together, the methanol leaf extract of A. elliptifolia might contains bioactive compounds for inhibiting ATG4B and autophagy activity to diminish viability and mobility of CRC cells, indicating its potential as an anti‐CRC drug for future development.","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"12 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0