Advanced Materials最新文献_第4页

In Situ Polymerized Polyfluorinated Crosslinked Polyether Electrolytes for High-Voltage Lithium Metal Batteries 高压锂金属电池用原位聚合多氟交联聚醚电解质

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-05-02 DOI: 10.1002/adma.202504333

Shimei Li, Hu Hong, Xinru Yang, Dedi Li, Qi Xiong, Dechao Zhang, Shixun Wang, Zhaodong Huang, Haiming Lv, Chunyi Zhi

{"title":"In Situ Polymerized Polyfluorinated Crosslinked Polyether Electrolytes for High-Voltage Lithium Metal Batteries","authors":"Shimei Li, Hu Hong, Xinru Yang, Dedi Li, Qi Xiong, Dechao Zhang, Shixun Wang, Zhaodong Huang, Haiming Lv, Chunyi Zhi","doi":"10.1002/adma.202504333","DOIUrl":"https://doi.org/10.1002/adma.202504333","url":null,"abstract":"In situ polymerized polyether electrolytes are promising for solid-state Li metal batteries due to their high ionic conductivity and excellent interfacial contact. However, their practical application is hindered by Li dendrite formation, interfacial degradation, and limited oxidative stability. Herein, we propose an in situ polymerized polyfluorinated crosslinked polyether electrolyte (PDOL-OFHDBO), synthesized by copolymerizing 1,3-dioxolane (DOL) with 2,2′-(2,2,3,3,4,4,5,5-octafluorohexane-1,6-diyl)bis(oxirane) (OFHDBO) as a polyfluorinated crosslinker. The electron-withdrawing polyfluorinated groups endow PDOL-OFHDBO with enhanced oxidative stability and interfacial compatibility, while reducing the solvation power of the polymer matrix to promote an anion-derived inorganic-rich solid electrolyte interphase for uniform Li deposition. Consequently, PDOL-OFHDBO exhibits a wide electrochemical stability window (>5.6 V) and enables long-term stable Li plating/stripping for over 1100 h. Furthermore, Li||LiNi0.8Co0.1Mn0.1O2 (NCM811) full cells utilizing PDOL-OFHDBO demonstrate outstanding cycling stability with high-loading cathodes (≈3.8 mAh cm−2) and thin Li anodes (50 µm), achieving capacity retention of 95.5% and 89.1% over 100 cycles at cut-off voltages of 4.3 and 4.5 V, respectively. Remarkably, Ah-level Li||NCM811 pouch cells deliver an impressive specific energy of 401.8 Wh kg−1, highlighting their potential for practical solid-state Li metal batteries.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"21 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143897786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unperceivable Designs of Wearable Electronics 可穿戴电子产品的不可感知设计

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-05-02 DOI: 10.1002/adma.202502727

Yijun Liu, Séverine De Mulatier, Naoji Matsuhisa

{"title":"Unperceivable Designs of Wearable Electronics","authors":"Yijun Liu, Séverine De Mulatier, Naoji Matsuhisa","doi":"10.1002/adma.202502727","DOIUrl":"https://doi.org/10.1002/adma.202502727","url":null,"abstract":"Wearable smart electronics are taking an increasing part of the consumer electronics market, with applications in advanced healthcare systems, entertainment, and Internet of Things. The advanced development of flexible, stretchable, and breathable electronic materials has paved the way to comfortable and long-term wearables. However, these devices can affect the wearer's appearance and draw attention during use, which may impact the wearer's confidence and social interactions, making them difficult to wear on a daily basis. Apart from comfort, one key condition for user acceptance is that these new technologies seamlessly integrate into our daily lives, remaining unperceivable to others. In this review, strategies to minimize the visual impact of wearable devices and make them more suitable for daily use are discussed. These new devices focus on being unperceivable when worn and comfortable enough that users almost forget their presence, reducing psychological discomfort while maintaining accuracy in signal collection. Materials selection is crucial for developing long-term and unperceivable wearable devices. Recent developments in these unperceivable electronic devices are also covered, including sensors, transistors, and displays, and mechanisms to achieve unperceivability are discussed. Finally, the potential applications are summarized and the remaining challenges and prospects are discussed.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"24 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143897858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Harnessing Spin-Lattice Interplay in Metal Nitrides for Efficient Ammonia Electrosynthesis 利用金属氮化物中的自旋-晶格相互作用进行高效氨电合成

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-04-30 DOI: 10.1002/adma.202504505

Xunlu Wang, Jiacheng (Jayden) Wang, Huashuai Hu, Congling Yin, Lo-Yueh Chang, Ye Zhu, Jiacheng Wang, Minghui Yang

{"title":"Harnessing Spin-Lattice Interplay in Metal Nitrides for Efficient Ammonia Electrosynthesis","authors":"Xunlu Wang, Jiacheng (Jayden) Wang, Huashuai Hu, Congling Yin, Lo-Yueh Chang, Ye Zhu, Jiacheng Wang, Minghui Yang","doi":"10.1002/adma.202504505","DOIUrl":"https://doi.org/10.1002/adma.202504505","url":null,"abstract":"Metal nitrides, renowned for their spin-lattice-charge interplay, offer vast potential in catalysis, electronics, and energy conversion. However, spin polarization manipulation in these nitrides remains a challenge for multi-electron electrocatalytic processes. This study introduces Co3Mo3N with a low-spin polarization configuration, achieved by incorporating spin-free lattice Mo with 4d orbitals into high-spin polarization Co4N. This innovation delivers outstanding nitrate-to-ammonia electrosynthesis, ranking among the best to date. Mo inclusion induces competing magnetic exchange interactions, reducing the spin polarization degree and enabling rate-determining step of NO2* to NO-OH* conversion via vertex-sharing NMo6 octahedra. A paired electro-refinery with a Co3Mo3N cathode achieves 2 000 mA cm−2 at 2.28 V and sustains an industrial-scale current of 1 000 mA cm−2 for 2,100 h, with an NH3 production rate of ≈70 mg NH3 h−1 cm−2. This work establishes a transformative platform for spin polarization degree-engineered electrocatalysts, driving breakthroughs in energy conversion technologies.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"41 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143889487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emergent Locomotion in Self-Sustained, Mechanically Connected Soft Matter Ringsf 自维持、机械连接软物质环中的紧急运动

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-04-30 DOI: 10.1002/adma.202503519

Hongshuang Guo, Kai Li, Arri Priimagi, Hao Zeng

{"title":"Emergent Locomotion in Self-Sustained, Mechanically Connected Soft Matter Ringsf","authors":"Hongshuang Guo, Kai Li, Arri Priimagi, Hao Zeng","doi":"10.1002/adma.202503519","DOIUrl":"https://doi.org/10.1002/adma.202503519","url":null,"abstract":"In nature, the interplay between individual organisms often leads to the emergence of complex belabours, of which sophistication has been refined through millions of years of evolution. Synthetic materials research has focused on mimicking the natural complexity, e.g., by harnessing non-equilibrium states to drive self-assembly processes. However, it is highly challenging to understand the interaction dynamics between non-equilibrium entities and to obtain collective behavior that can arise autonomously through interaction. In this study, thermally fueled, twisted rings exhibiting self-sustained movements are used as fundamental units and their interactive behaviors and emergent functions are investigated. The rings are fabricated from connected thermoresponsive liquid crystal elastomers (LCEs) strips that undergo zero-elastic-energy-mode, autonomous motions upon a heat gradient. Single-ring structures with various twisting numbers and nontrivial links, and connected knots where several LCE rings (N = 2,3,4,5) are studied and linked. The observations uncover that controlled locomotion of the structures can emerge when N ≥ 3. The locomotion can be programmed by controlling the handedness at the connection points between the individual rings. These findings illustrate how group activity emerges from individual responsive material components through mechanical coupling, offering a model for programming autonomous locomotion in soft matter constructs.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"67 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143889508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Near Infrared Light-Based Non-Contact Sensing System for Robotics Applications 基于近红外光的机器人应用非接触传感系统

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-04-30 DOI: 10.1002/adma.202414481

Ran Wang, Yu Cheng, Qiran Zhang, Haoran Li, Yangyang Wang, Jiaqi Liu, Ruirui Xing, Jinming Ma, Tifeng Jiao

{"title":"Near Infrared Light-Based Non-Contact Sensing System for Robotics Applications","authors":"Ran Wang, Yu Cheng, Qiran Zhang, Haoran Li, Yangyang Wang, Jiaqi Liu, Ruirui Xing, Jinming Ma, Tifeng Jiao","doi":"10.1002/adma.202414481","DOIUrl":"https://doi.org/10.1002/adma.202414481","url":null,"abstract":"With the development of artificial intelligence and the Internet of Things, non-contact sensors are expected to realize complex human-computer interaction. However, current non-contact sensors are mainly limited by accuracy and stability. Herein, an intelligent infrared photothermal non-contact sensing system is developed that provides long-distance and high-accuracy non-contact sensing. A black phosphorus (BP)-based composite organogel is designed, which exhibits excellent photothermal properties and environmental stability, as the active material. This material can detect patterns created by near-infrared (NIR) light through various patterned masks monitored by an infrared thermal imager. The constructed non-contact sensing system is capable of accurately recognizing 26 letters with an impressive accuracy rate of 99.4%. Furthermore, even small size non-contact sensors can maintain high sensitivity and stability across a wide temperature range, at long working distances, and under different current intensities and dark conditions, demonstrating exceptional robustness. Combined with machine learning method, it is demonstrated that the non-contact sensing system excels in pattern recognition and human-computer interaction. These features highlight its potential applications in intelligent robotics and remote control systems.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"10 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143889509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-Sintering Ni-W Catalytic Layer on Reductive Tungsten Carbides for Superior High-Temperature CO2 Reduction 还原性碳化钨抗烧结Ni-W催化层超高温CO2还原

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-04-30 DOI: 10.1002/adma.202504431

Daoping Ye, Zihe Wu, Ting Wang, Ran Zhu, Yifan Feng, Jiwei Lei, Yu Tian, Zongpeng Zou, Hao Wu, Chong Cheng, Shengwei Tang, Shuang Li

{"title":"Anti-Sintering Ni-W Catalytic Layer on Reductive Tungsten Carbides for Superior High-Temperature CO2 Reduction","authors":"Daoping Ye, Zihe Wu, Ting Wang, Ran Zhu, Yifan Feng, Jiwei Lei, Yu Tian, Zongpeng Zou, Hao Wu, Chong Cheng, Shengwei Tang, Shuang Li","doi":"10.1002/adma.202504431","DOIUrl":"https://doi.org/10.1002/adma.202504431","url":null,"abstract":"The reverse water-gas shift (RWGS) reaction stands out as a promising approach for selectively converting CO2 into CO, which can then be upgraded into high-value-added products. While designing high selectivity and stability catalysts for RWGS reaction remains a significant challenge. In this study, an efficient and ultra-stable Ni-W catalytic layer on reductive WC (NiAWC) is designed as an anti-sintering catalyst for superior high-temperature RWGS reaction. Benefiting from the unique structures, the NiAWC catalyst exhibits exceptionally high performances with a CO production rate of 1.84 molCO gNi−1 h−1 and over 95% CO selectivity, maintaining stability for 120 h at 500 °C. Even after 300 h of continuous testing at 600 °C and five aging cycles at 800 °C, the activity loss is only 0.34% and 0.83%, respectively. Unlike the conventional mechanism in RWGS reaction, it is demonstrated that the Ni-W limited coordination can stabilize the Ni sites and allow a pre-oxidation of Niδ+ by CO, which produces an O* electronic reservoir and hinders the charge transfer from Ni to W-O, thereby avoiding the dissolution of Ni atoms. The design of new, efficient, and selective catalysts through metal-substrate synergistic effects is suggested to offer a promising path to engineering superior thermal catalysts.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"12 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143889505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Monitoring α/β Particles Using a Copper Cluster Scintillator Detector 利用铜簇闪烁体探测器监测α/β粒子

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-04-30 DOI: 10.1002/adma.202504425

Qiu-Chen Peng, Ruo-Yu Cao, Qi Yang, Yu-Bing Si, Jia-Wang Yuan, Ying-Ying Lei, Zhao-Yang Wang, Qiang Tang, Kai Li, Shuang-Quan Zang

{"title":"Monitoring α/β Particles Using a Copper Cluster Scintillator Detector","authors":"Qiu-Chen Peng, Ruo-Yu Cao, Qi Yang, Yu-Bing Si, Jia-Wang Yuan, Ying-Ying Lei, Zhao-Yang Wang, Qiang Tang, Kai Li, Shuang-Quan Zang","doi":"10.1002/adma.202504425","DOIUrl":"https://doi.org/10.1002/adma.202504425","url":null,"abstract":"High-energy radiation is widely used in medicine, industry, and scientific research. Meanwhile, the detection of environmental ionizing radiation is essential to ensure the safe use of high-energy radiation. Among radiation detectors, scintillator detectors offer multiple advantages, including simple structure, high sensitivity, excellent environmental adaptability, and a favorable performance-to-price ratio. However, the development of high-performance scintillators that can provide highly sensitive responses to environmental radiation, especially α/β particles, remains a challenge. In this work, a copper cluster (Cu4I4(DPPPy)2) with excellent water-oxygen stability is prepared using a simple one-pot method at room temperature. Cu4I4(DPPPy)2 not only exhibits excellent X-ray excited luminescence (XEL) under X-ray irradiation but also demonstrates a highly sensitive scintillation response to α/β particles. By integrating Cu4I4(DPPPy)2 with a photomultiplier tube (PMT) and nuclear electronics, an α/β surface contamination monitor is successfully developed. This monitor enables the sensitive detection of excessive α/β particles in real-world environments. The detection frequency and signal intensity of Cu4I4(DPPPy)2 significantly surpass those of commercial scintillator of YAP:Ce, BGO, PbWO4, and anthracene under identical conditions, highlighting the promising application of metal clusters in low-dose environmental radiation detection.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"88 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143889503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zwitterionic Brush-Grafted Interfacial Bio-Lubricant Evades Complement C3-Mediated Macrophage Phagocytosis for Osteoarthritis Therapy 两性离子刷接界面生物润滑剂避免补体c3介导的巨噬细胞吞噬治疗骨关节炎

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-04-30 DOI: 10.1002/adma.202501137

Chuandong Cai, Mingwei Wang, Luman Wang, Jiangtao Guo, Lipeng Wang, Yingkai Zhang, Guohao Wu, Bingxuan Hua, Martien A. Cohen Stuart, Xuhong Guo, Lu Cao, Zuoqin Yan

{"title":"Zwitterionic Brush-Grafted Interfacial Bio-Lubricant Evades Complement C3-Mediated Macrophage Phagocytosis for Osteoarthritis Therapy","authors":"Chuandong Cai, Mingwei Wang, Luman Wang, Jiangtao Guo, Lipeng Wang, Yingkai Zhang, Guohao Wu, Bingxuan Hua, Martien A. Cohen Stuart, Xuhong Guo, Lu Cao, Zuoqin Yan","doi":"10.1002/adma.202501137","DOIUrl":"https://doi.org/10.1002/adma.202501137","url":null,"abstract":"Administering a bio-lubricant is a promising therapeutic approach for the treatment of osteoarthritis (OA), in particular, if it can both manage symptoms and halt disease progression. However, the clearance of these bio-lubricants mediated by synovial macrophages leads to reduced therapeutic efficiency and adverse inflammatory responses. Herein, it is shown that this process is predominantly mediated by the specific binding of complement C3 (on nanoparticle) and CD11b (on macrophage). More importantly, through a systematic evaluation of various interface modifications, a macrophage-evading nanoparticle strategy is proposed, which not only minimizes friction, but also largely suppresses C3 adsorption. It involves employing a zwitterionic poly-2-methacryloyloxyethyl phosphorylcholine (PMPC) brush layer grafted from a crosslinked gelatin core. In vitro studies demonstrate that such a nanoparticle lubricant can evade macrophage phagocytosis and further prevent the pro-inflammatory M1 polarization and subsequent harmful release of cytokines. In vivo studies show that the designed PMPC brush layer effectively mitigates synovial inflammation, alleviates OA-associated pain, and protects cartilage from degeneration, thus preventing OA progression. These findings clarify the pivotal role of complement C3-mediated macrophage recognition in nanoparticles clearance and offer a promising nanoparticle design strategy to restore joint lubrication.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"7 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143889504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanical Resonant Sensing of Spin Texture Dynamics in a 2D Antiferromagnet 二维反铁磁体中自旋织构动力学的机械共振传感

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-04-30 DOI: 10.1002/adma.202420168

S M Enamul Hoque Yousuf, Yunong Wang, Shreyas Ramachandran, John Koptur-Palenchar, Chiara Tarantini, Li Xiang, Stephen McGill, Dmitry Smirnov, Elton J. G. Santos, Philip X.-L. Feng, Xiao-Xiao Zhang

{"title":"Mechanical Resonant Sensing of Spin Texture Dynamics in a 2D Antiferromagnet","authors":"S M Enamul Hoque Yousuf, Yunong Wang, Shreyas Ramachandran, John Koptur-Palenchar, Chiara Tarantini, Li Xiang, Stephen McGill, Dmitry Smirnov, Elton J. G. Santos, Philip X.-L. Feng, Xiao-Xiao Zhang","doi":"10.1002/adma.202420168","DOIUrl":"https://doi.org/10.1002/adma.202420168","url":null,"abstract":"The coupling between the spin degrees of freedom and macroscopic mechanical motions, including striction, shearing, and rotation, has attracted wide interest with applications in actuation, transduction, and information processing. Experiments so far have established the mechanical responses to the long-range ordered or isolated single spin states. However, it remains elusive whether mechanical motions can couple to a different type of magnetic structure, the non-collinear spin textures, which exhibit nanoscale spatial variations of spin (domain walls, skyrmions, etc.) and are promising candidates to realize high-speed computing devices. Here, collective spin texture dynamics is detected with nanoelectromechanical resonators fabricated from 2D antiferromagnetic (AFM) MnPS3 with 10−9 strain sensitivity. By examining radio frequency mechanical oscillations under magnetic fields, new magnetic transitions are identified with sharp dips in resonant frequency. They are attributed to collective AFM domain wall motions as supported by the analytical modeling of magnetostriction and large-scale spin-dynamics simulations. Additionally, an abnormally large modulation in the mechanical nonlinearity at the transition field infers a fluid-like response due to ultrafast domain motion. The work establishes a strong coupling between spin texture and mechanical dynamics, laying the foundation for electromechanical manipulation of spin texture and developing quantum hybrid devices.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"19 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143889507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-Resolution Patterned Delivery of Chemical Signals From 3D-Printed Picoliter Droplet Networks 3d打印皮升液滴网络的高分辨率模式化学信号传递

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-04-30 DOI: 10.1002/adma.202412292

Jorin Riexinger, Thomas Caganek, Xingzao Wang, Yutong Yin, Khoa Chung, Linna Zhou, Hagan Bayley, Ravinash Krishna Kumar

{"title":"High-Resolution Patterned Delivery of Chemical Signals From 3D-Printed Picoliter Droplet Networks","authors":"Jorin Riexinger, Thomas Caganek, Xingzao Wang, Yutong Yin, Khoa Chung, Linna Zhou, Hagan Bayley, Ravinash Krishna Kumar","doi":"10.1002/adma.202412292","DOIUrl":"https://doi.org/10.1002/adma.202412292","url":null,"abstract":"Synthetic cells, such as giant unilamellar vesicles, can be engineered to detect and release chemical signals to control target cell behavior. However, control over target-cell populations is limited due to poor spatial or temporal resolution and the inability of synthetic cells to deliver patterned signals. Here, 3D-printed picoliter droplet networks are described that direct gene expression in underlying bacterial populations by patterned release of a chemical signal with temporal control. Shrinkage of the droplet networks prior to use achieves spatial control over gene expression with ≈50 µm resolution. Ways to store chemical signals in the droplet networks and to activate release at controlled points in time are also demonstrated. Finally, it is shown that the spatially-controlled delivery system can regulate competition between bacteria by inducing the patterned expression of toxic bacteriocins. This system provides the groundwork for the use of picoliter droplet networks in fundamental biology and in medicine in applications that require the controlled formation of chemical gradients (i.e., for the purpose of local control of gene expression) within a target group of cells.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"34 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143889506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0