{"title":"Accidents disrupt integration into the labour market and affect health of migrants and refugees.","authors":"Leela Sengupta Carstensen, Morten Sodemann","doi":"10.61409/A03250180","DOIUrl":"https://doi.org/10.61409/A03250180","url":null,"abstract":"<p><strong>Introduction: </strong>Globally, migrants are exposed to hazardous working environments, frequently placing their safety and health at risk. The Danish Migrant Health Clinic identified that 11% of referred patients reported an occupational injury as the primary cause of their ill health. The aim of this study was to describe common accidents and their adverse effects in migrant patients.</p><p><strong>Methods: </strong>From March 2018 to November 2021, we purposively sampled and included patients through the Danish Migrant Health Clinic. The inclusion criteria were qualitative descriptions of accidents defined as inadvertent events that cause significant social, psychological or physical changes at the functional level. We reviewed the health record, summarised the case descriptions and identified dominant themes.</p><p><strong>Results: </strong>We included 52 patients and identified the themes: 1) Occupational accidents, 2) Psychological and cognitive consequences, 3) Racism and discrimination, 4) Occupational trauma of interpreters and 5) Social and economic detour following an accident. Accidents lead to chronic pain conditions, primarily post-traumatic stress disorder or re-traumatisation, loss of language skills and work retention challenges. Furthermore, patients with occupational accidents reported poor knowledge about legal and insurance rights.</p><p><strong>Conclusions: </strong>An accident may initiate, reproduce or accelerate poor health and a psycho-social detour for migrant patients. Workers' unions should inform migrant members about legal and insurance rights. of this subject among health professionals, unions and social workers could improve prevention interventions.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 5","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eline Panadevo, Peter Thye-Rønn, Katrine Schultz Overgaard, Kenneth Egstrup, Jess Lambrechtsen, Søren Auscher
{"title":"The prevalence and treatment of chronic kidney disease in a cardiology outpatient clinic.","authors":"Eline Panadevo, Peter Thye-Rønn, Katrine Schultz Overgaard, Kenneth Egstrup, Jess Lambrechtsen, Søren Auscher","doi":"10.61409/A08250635","DOIUrl":"https://doi.org/10.61409/A08250635","url":null,"abstract":"<p><strong>Introduction: </strong>Patients with cardiovascular and chronic kidney disease (CKD) are at increased risk of adverse outcomes, calling for early monitoring of kidney function to reduce morbidity and mortality. We aimed to estimate CKD prevalence, albuminuria, kidney monitoring practices and adherence to guideline-recommended treatment in cardiology outpatients.</p><p><strong>Methods: </strong>This cross-sectional study included 196 patients from a cardiology outpatient clinic in Svendborg, Denmark. Blood and urine samples were analysed for the estimated glomerular filtration rate (eGFR), urine albumin-to-creatinine ratio and secondary markers of kidney impairment, in accordance with international guidelines. Medical history, risk factors and demographic information were obtained from a questionnaire. Regular CKD monitoring (≥ 1 ×/year) and nephroprotective drug use were evaluated.</p><p><strong>Results: </strong>The prevalence of CKD was 50.5%, and 20.9% of patients were categorised with a high or very high CKD risk. In patients with CKD, 23.2% had albuminuria despite normal eGFR, 22.2% had secondary markers of kidney impairment, and only 15.2% were aware of having reduced kidney function. Regular kidney monitoring was lacking in 33.7% of patients, and 64.3% of patients with CKD did not receive the recommended treatment.</p><p><strong>Conclusions: </strong>The prevalence of CKD was high in cardiology outpatients. Limited awareness of kidney function, in combination with infrequent screening of CKD, led to inadequate prescription of nephroprotective drugs.</p><p><strong>Funding: </strong>Funded by the Cardiovascular Research Unit, Odense University Hospital Svendborg.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 5","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mads-Emil Kjærsgaard, Regitze Dam Gade, Søren Kold, Ole Rahbek, Hans-Christen Husum
{"title":"Reduced effectiveness of the selective hip dysplasia screening programme over time.","authors":"Mads-Emil Kjærsgaard, Regitze Dam Gade, Søren Kold, Ole Rahbek, Hans-Christen Husum","doi":"10.61409/A05250441","DOIUrl":"https://doi.org/10.61409/A05250441","url":null,"abstract":"<p><strong>Introduction: </strong>Selective ultrasound screening for developmental dysplasia of the hip (DDH) was implemented in the North Denmark Region, Denmark in 2010 but has yet to be evaluated. This study aimed to evaluate selective hip screening in the North Denmark Region from 2010 to 2021, focusing on referral rates, the incidence of DDH and referral causes.</p><p><strong>Methods: </strong>We retrospectively identified 3,812 infants (2,091 females) who were referred during a 12-year period for hip ultrasound at Aalborg University Hospital in Denmark. DDH was defined as an ultrasound classification of Graf type IIb or worse. Referral rates and the incidence of DDH and their development over the study period were examined.</p><p><strong>Results: </strong>During the study period, there was a steadily increasing referral rate, with the annual referral rate doubling from 200 (3.3%) in 2010 to 402 (6.8%) in 2021, whereas the incidence rate increased only minimally from 0.15% to 0.22%. The most common referral causes were breech position (41.4%) and positive clinical exam (27.8%).</p><p><strong>Conclusions: </strong>During the study period, the annual referral rate nearly doubled without a corresponding increase in DDH incidence, suggesting that the screening programme has become less efficient over time. This might explain the relatively low incidence of DDH in the North Denmark Region compared with national and international studies.</p><p><strong>Funding: </strong>The authors received no financial support for the research, authorship and/or publication of this article.</p><p><strong>Trial registration: </strong>This study was registered in the North Denmark Regional internal Project Register as IDF2022-187.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 5","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of children with irritable bowel syndrome in general practice - a systematic review.","authors":"Erika Anne Mengel, Gritt Overbeck","doi":"10.61409/A08250661","DOIUrl":"https://doi.org/10.61409/A08250661","url":null,"abstract":"<p><strong>Introduction: </strong>Irritable bowel syndrome (IBS) is the most frequently reported paediatric functional abdominal pain disorder (FAPD). It impacts quality of life, contributes to school absenteeism and can result in chronic pain. This review investigated the management of children with IBS in general practice regarding diagnostic evaluation, use of the Rome Criteria, diagnostic outcomes, referrals, prescriptions and follow-ups.</p><p><strong>Methods: </strong>A systematic review was conducted following the PRISMA guidelines. Studies were identified through a structured PubMed search and screened using predefined inclusion criteria. Eligible studies focused on general practitioners' management of children with episodic abdominal pain, in which IBS could be a subtype. Data were reported narratively due to heterogeneity across studies.</p><p><strong>Results: </strong>Five observational studies involving over 4,300 children were included. The proportion of children receiving a functional diagnosis ranged from 16% to 84%, and the Rome Criteria were rarely used (7-27% of cases). Blood and urine tests were commonly used. Prescriptions and referrals differed across studies. Follow-up was rare.</p><p><strong>Conclusions: </strong>IBS is the most common FAPD in children. Though often managed by general practitioners, it remains unclear how they diagnose and treat these cases. The Rome Criteria appear to be rarely used, and diagnosis frequency varies, suggesting some children may be overlooked or misclassified. Follow-up is infrequent, and it is unclear whether a biopsychosocial approach is used. More research is needed to understand and improve care in this setting.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 5","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karoline Korsholm Jeppesen, Rasmus Bo Lindhardt, Anika Klein, Emma Illum, Rasmus Bank Lynggaard, Ann Banke, Jacob Eifer Møller, Hanne Berg Ravn, Pernille Just Vinholt
{"title":"Evaluation of AI-assisted chart review for acute myocardial infarction and cardiogenic shock.","authors":"Karoline Korsholm Jeppesen, Rasmus Bo Lindhardt, Anika Klein, Emma Illum, Rasmus Bank Lynggaard, Ann Banke, Jacob Eifer Møller, Hanne Berg Ravn, Pernille Just Vinholt","doi":"10.61409/A10250874","DOIUrl":"https://doi.org/10.61409/A10250874","url":null,"abstract":"<p><strong>Introduction: </strong>The Danish RETROSHOCK registry has provided valuable insights into patients with acute myocardial infarction complicated by cardiogenic shock (AMICS) and their clinical trajectories. However, continuously updating the registry through manual chart review is time-consuming.</p><p><strong>Methods: </strong>Electronic medical records were retrieved from patients admitted to Odense University Hospital from 2018 to 2022, assigned an ICD-10 code suggestive of AMICS. A random sample of 100 consecutive patients was selected for testing the AI-assisted chart review. The AI tool was a natural language processing model identifying AMICS-related keywords. Electronic medical records were initially screened using AI-assisted chart review, with time recorded until AMICS diagnosis or exclusion due to an alternative diagnosis. One week later, a manual chart review was performed. AI-assisted and manual screening times were compared using the Wilcoxon signed-rank test.</p><p><strong>Results: </strong>AI-assisted chart review identified the same 26 AMICS patients as manual review (Cohen's kappa = 1). Median manual inclusion time was 2:20 minutes, compared with 1:16 minutes with AI-assisted chart review (p less-than 0.001). Median manual exclusion time was 2:45 minutes, and AI-assisted exclusion was 0:59 minutes (p less-than 0.001).</p><p><strong>Conclusions: </strong>AI-assisted chart review significantly reduced screening time for including AMICS patients in the RETROSHOCK registry and excluding non-eligible patients, while preserving diagnostic accuracy.</p><p><strong>Funding: </strong>The RETROSHOCK database is supported by Johnson and Johnson Med Tech and the Novo Nordic Foundation.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 5","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peter Joseph Wartenberg, Andrea Nedergaard Jensen, Alexander Kai Thomsen, Torben Lykke Sørensen
{"title":"Geographical disparities in visual acuity at diagnosis among patients with neovascular age-related macular degeneration.","authors":"Peter Joseph Wartenberg, Andrea Nedergaard Jensen, Alexander Kai Thomsen, Torben Lykke Sørensen","doi":"10.61409/A05250419","DOIUrl":"https://doi.org/10.61409/A05250419","url":null,"abstract":"<p><strong>Introduction: </strong>Neovascular age-related macular degeneration (nAMD) affects approximately 8% of the global population. While socioeconomic and geographical disparities have been increasingly studied in Denmark, geographical disparity in best corrected visual acuity (BCVA) at the time of diagnosis in nAMD remains understudied. This study aimed to investigate possible geographical disparity in BCVA at the time of diagnosis in nAMD patients in Region Zealand, Denmark.</p><p><strong>Methods: </strong>This was a retrospective study using data from the database \"Bedre Oftalmologi for Brugere\" from 2011 to 2021. BCVA was extracted for patients at the time of diagnosis with nAMD. Patients were grouped geographically by postal code and municipality. Data were analysed using the Kruskal-Wallis test to investigate geographical disparity and stratified by sex.</p><p><strong>Results: </strong>A total of 4,266 eyes with nAMD were included. Variations in BCVA at the time of nAMD diagnosis were found between geographical regions in Region Zealand at postal code level and at municipality level. Furthermore, we found a disparity between municipalities among males and females. However, no statistically significant disparity between postal codes was found among males or females.</p><p><strong>Conclusions: </strong>There was a significant geographical disparity in BCVA at the time of diagnosis in nAMD patients, inviting further investigation to determine the extent and roots of this disparity.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 5","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karen Marie Egsgaard, Steen Jensen, Thomaz Piotr Tabor
{"title":"Unexpected high-risk neoplasias among routine skin specimens.","authors":"Karen Marie Egsgaard, Steen Jensen, Thomaz Piotr Tabor","doi":"10.61409/A09250776","DOIUrl":"https://doi.org/10.61409/A09250776","url":null,"abstract":"<p><strong>Introduction: </strong>Turnaround time (TAT) for routine skin specimens may be prolonged at times, delaying diagnosis and treatment in cases with a unexpected high-risk neoplasia. This quality improvement study assessed the prevalence, types and characteristics of such cases.</p><p><strong>Methods: </strong>This was a descriptive study of all routine skin specimens submitted by general practitioners (GPs) and private dermatologists in 2022-2023 at the Department of Pathology, Viborg Regional Hospital, Denmark. From Systematized Nomenclature of Medicine (SNOMED) codes, various premalignant and malignant neoplasias were identified; melanocytic and soft tissue neoplasms were included.</p><p><strong>Results: </strong>Among 33,280 routine specimens, 77 (0.23%) were a high-risk premalignant or malignant neoplasia: 66 melanocytic (54 melanomas, 0.16%) and 11 sarcomas. Superficial spreading melanoma (n = 36) and the in situ variant (n = 10) were the most frequent high-risk neoplasia in lesions clinically assessed as benign. Among melanocytic lesions, 61% had involved/unassessable margins, and 67% of melanomas had a depth ≥ 1.0 mm. The mean TAT was 64 calendar days. Mean age: 64.1 years, with a notable proportion aged 41-50 years. Referrals: GPs 73%, dermatologists 26%, surgeons 1%.</p><p><strong>Procedures: </strong>excision 58%, curettage 25%, biopsy 10%, unspecified 7%. Suspicious shape/colour features were noted in 36% of melanocytic lesions. 7.5% had prior melanoma.</p><p><strong>Conclusions: </strong>Unexpected high-risk neoplasia are rare (0.23%) but often advanced, highlighting the need for improved clinical assessment and a short TAT for routine skin specimens. The results serve as a reference for future AI-based screening.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 5","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emilie Melgaard, Lucas Malta Westergaard, Anne Sophie Olesen, Kristina Miger, Sandra Tonning, Silas Nyboe Ørting, Jens Petersen, Olav Wendelboe Nielsen, Johannes Grand
{"title":"Heart size on chest CT and its association with acute heart failure in the emergency department.","authors":"Emilie Melgaard, Lucas Malta Westergaard, Anne Sophie Olesen, Kristina Miger, Sandra Tonning, Silas Nyboe Ørting, Jens Petersen, Olav Wendelboe Nielsen, Johannes Grand","doi":"10.61409/A09250765","DOIUrl":"https://doi.org/10.61409/A09250765","url":null,"abstract":"<p><strong>Introduction: </strong>Acute appendicitis is a common surgical emergency, but accurate diagnosis remains challenging. Despite the 2020 World Society of Emergency Surgery Jerusalem guidelines recommending structured imaging pathways, including ultrasound and selective computed tomography, clinical assessment remains the primary diagnostic tool in Denmark. Contemporary practice emphasises rapid assessment, with imaging reserved for older or borderline cases. We hypothesised that reliance on clinical assessment alone contributes to a high number of negative appendectomies, particularly in young adults.</p><p><strong>Methods: </strong>We conducted a single-centre retrospective cohort study of adults (> 18 years) undergoing surgery for suspected appendicitis at a tertiary university hospital in Denmark between January 2021 and December 2023. Data were extracted from electronic medical records and analysed in Stata 19.5.</p><p><strong>Results: </strong>Among 613 patients, 522 had histologically confirmed appendicitis, yielding an overall negative appendectomy rate (NAR) of 14.9%. Patients without preoperative imaging (n = 279) had a NAR of 24.4%, compared with 6.9% among those who underwent preoperative imaging (n = 334).</p><p><strong>Conclusions: </strong>Reliance on clinical assessment alone results in a substantial number of unnecessary operations. Preoperative imaging significantly reduces NAR (p less-than 0.001), supporting broader adoption of guideline-based diagnostic strategies to improve diagnostic accuracy and optimise resource utilisation.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 5","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Louise Nørgaard Olsen, Philipp Harbig, Kaj Sparle Christensen, Morten Bondo Christensen
{"title":"Acute hospital admissions among elderly patients in Danish general practice.","authors":"Louise Nørgaard Olsen, Philipp Harbig, Kaj Sparle Christensen, Morten Bondo Christensen","doi":"10.61409/A09250708","DOIUrl":"https://doi.org/10.61409/A09250708","url":null,"abstract":"<p><strong>Introduction: </strong>The rising number of acute hospital admissions among elderly patients exerts substantial pressure on the healthcare system, and many of these admissions could potentially be prevented. This pilot study aimed to explore patterns in the frequency and duration of acute hospitalisations in elderly patients (≥ 65 years).</p><p><strong>Methods: </strong>A retrospective chart review was conducted in a solo general practice in Aarhus, Denmark, examining acute hospital admissions among elderly patients from 1 November 2022 to 1 November 2024. Data were extracted on 11 November 2024. The review identified 44 patients with a total of 70 admissions. The study explored associations between selected characteristics and short-term versus longer acute hospital admissions. For comparison, data drawn from a larger practice included 195 patients and 322 admissions.</p><p><strong>Results: </strong>Nearly half of all acute admissions lasted one day or less, with 30% concluding in discharge from an emergency department. Language barriers were associated with longer stays, whereas no other examined characteristics showed significant associations. Diagnosis was often recorded using broad ICD-10 categories, particularly for short stays.</p><p><strong>Conclusions: </strong>Short-term admissions in elderly patients are common, yet difficult to predict. Many may stem from clinical uncertainty or system constraints. Larger practice-based studies are needed to better understand and address avoidable admissions in this vulnerable population.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 5","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sükriye Corap Gellert, Abdullahi Abdirisak Hirsi, Michael Brix, Bjarke Viberg
{"title":"Adding glue to the surgical site after surgery for lower-extremity fractures.","authors":"Sükriye Corap Gellert, Abdullahi Abdirisak Hirsi, Michael Brix, Bjarke Viberg","doi":"10.61409/A11250949","DOIUrl":"https://doi.org/10.61409/A11250949","url":null,"abstract":"<p><strong>Introduction: </strong>Surgical site infection is a concern after lower-extremity fracture surgery, and post-operative wound oozing may increase this risk. Applying glue to the incision could reduce oozing and thereby reduce the need for adhesive patch (AP) changes. This study compared AP change rates in adults with surgically treated lower-extremity fractures with and without the addition of wound glue.</p><p><strong>Methods: </strong>In this prospective cohort study, lower-extremity fractures treated surgically with implants were included, while external fixation and in-hospital deaths were excluded. Patients were enrolled over four months: two as controls and two with glue added to the wound. The primary outcome was AP change on all surgical wounds; secondary outcomes were AP change by fracture location, wound closure method and incision length (small: screw/nail; large: arthroplasty/plate). Follow-up continued throughout admission.</p><p><strong>Results: </strong>Among 339 patients, 162 received no glue and 177 received glue. The median age was 76 years, 55% were female and femoral fractures predominated. Groups were comparable at baseline. AP change occurred in 44% without glue and 35% with glue (p = 0.097). For large incisions, AP change was 42% without glue versus 27% with glue (p = 0.040). No differences were found by fracture location, surgery type or closure method.</p><p><strong>Conclusions: </strong>Adding glue showed no significant overall reduction in AP changes. However, in large incisions, glue reduced AP changes by 15 percentage points, suggesting a benefit in this subgroup.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 5","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}