Danish medical journal最新文献

{"title":"Real-world efficacy of tucatinib in Danish human epidermal growth factor receptor 2-positive metastatic breast cancer.","authors":"Laurits Sebastian Dahl, Ann Søegaard Knoop, Maj-Britt Jensen, Eva Harder, Jeanette Dupont Rønlev, Tobias Berg","doi":"10.61409/A11240821","DOIUrl":"https://doi.org/10.61409/A11240821","url":null,"abstract":"<p><strong>Introduction: </strong>Tucatinib in combination with trastuzumab and capecitabine is approved for the treatment of metastatic human epidermal growth factor receptor 2 (HER2) positive breast cancer in third-line and later based on the results of the HER2CLIMB trial. In this short report, we evaluate the extent and efficacy of tucatinib treatment among Danish patients.</p><p><strong>Methods: </strong>This is a retrospective study that includes all known Danish patients who initiated tucatinib prior to June 1, 2024. We utilised the nationwide clinical database of the Danish Breast Cancer.</p><p><strong>Results: </strong>In total, 38 patients were treated. Nineteen (50%) of the patients had central nervous system (CNS) metastases, and 21 (55%) had visceral disease. Median progression-free survival was 8.7 months (95% CI: 6.2; 13.3) and median overall survival was 22.4 months (95% CI: 13.1; N/A). Nine patients exhibited a performance status of 2-3 (n = 5) or uncontrollable CNS metastases (n = 4), not meeting the inclusion criteria applied in the HER2CLIMB trial.</p><p><strong>Conclusions: </strong>Our results align with data presented from the HER2CLIMB trial. Considerably fewer patients than initially expected have been treated in Denmark.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Approved by the Capital Regions Research Overview (P-2024-175774) and the Centre for Health Research (R-24065900).</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 10","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Danish cardiologists' attitude towards clinical AI support: a survey study.","authors":"Søren A Rand, Anna Kirstine Ringgaard, Anders Christian Riis-Jensen, Henning Bundgaard, Iben Mundbjerg Gjødsbøl, Johan Skov Bundgaard","doi":"10.61409/A01250019","DOIUrl":"https://doi.org/10.61409/A01250019","url":null,"abstract":"<p><strong>Introduction: </strong>AI represents a conceptual change in medicine, and AI-based tools are rapidly being developed and implemented in clinical medicine. This study aimed to evaluate how clinicians at selected Danish cardiology departments perceive the role of AI in clinical decision-making.</p><p><strong>Methods: </strong>We conducted a ten-item anonymous survey among clinicians in Danish cardiology departments to evaluate physicians' attitudes towards AI support in clinical decision-making for ischaemic heart disease. Key focus areas included perceived impact on patient outcomes, safety, workflow and clinician training. Responses were measured on a five-point Likert scale (1 = strongly disagree, 5 = strongly agree), with 4 or 5 collectively categorised as agreement. Participants were stratified by seniority (less-than 10 years versus ≥ 10 years).</p><p><strong>Results: </strong>A total of 60 Danish clinicians at cardiology departments participated. The highest level of agreement was observed for AI optimism/expectations (68%, mean: 3.7), willingness to invest time in training (65%, mean: 3.8) and interest in AI use (63%, mean: 3.6). Although nosignificant, junior clinicians showed greater enthusiasm for training and adoption, whereas concerns about trust, safety and time-saving potential persisted across seniority.</p><p><strong>Conclusions: </strong>Danish cardiologists generally expressed moderate to high expectations, interest and willingness towards AI support in clinical decision-making. However, the study revealed concerns about accuracy, patient safety and whether AI will ultimately save clinicians' time.</p><p><strong>Funding: </strong>This project was supported by NordForsk (PM-Heart grant number 90580), Novo Nordisk Foundation (grant no. NNF14CC0001, NNF17OC0027594 and NNF22OC0079382), Innovation Fund Denmark (BigTempHealth grant no. 5153-00002B, case no. 8114-00033B and 8114-00034B), Rigshospitalets Forskningspulje and Rigshospitalets Forskningspulje Rammebevilling (#A11336). The funders had no role in the design or interpretation of the study.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 10","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adaptation and interobserver agreement in a Danish translation of the Clinical Frailty Scale Questionnaire.","authors":"Line Houkjær, Stig Brorson","doi":"10.61409/A08240549","DOIUrl":"https://doi.org/10.61409/A08240549","url":null,"abstract":"<p><strong>Introduction: </strong>The Clinical Frailty Scale (CFS) assesses frailty in older adults. Although the scale has been translated into Danish, the accompanying questionnaire and classification tree have not. The questionnaire includes seven questions about basic and instrumental activities of daily living, chronic conditions, self-rated health, energy level and physical activity, guiding the respondent to a CFS level through the classification tree. This study translated and cross-culturally adapted the CFS questionnaire and classification tree into Danish and assessed the interobserver agreement in a hospital setting.</p><p><strong>Methods: </strong>The Danish version of the CFS short questionnaire and classification tree was developed in five stages: forward translations, synthesis, back-translation, review by a committee panel and pre-testing, followed by comprehension interviews and an interobserver agreement study.</p><p><strong>Results: </strong>The back-translations closely matched the original. Minor discrepancies in contextual and idiomatic expressions were resolved through committee review. Pre-test confirmed comprehension, requiring no further changes. The kappa for interobserver agreement was 0.78.</p><p><strong>Conclusions: </strong>The CFS questionnaire and classification tree were translated and cross-culturally adapted into Danish and are attached to this paper. The interobserver agreement achieved is considered acceptable for applying the CFS in emergency and orthopaedic departments.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 10","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical treatment of breast fibroadenomas.","authors":"Cecilie Jansen, Nethe Eichen, Niels Kroman, Tove Tvedskov","doi":"10.61409/A03250179","DOIUrl":"https://doi.org/10.61409/A03250179","url":null,"abstract":"<p><strong>Introduction: </strong>Fibroadenoma is a benign tumour with a prevalence of 9-22% and the third most common palpable breast tumour. Management is primarily conservative, but treatment varies due to a lack of national guidelines. We aimed to estimate the proportion of women diagnosed with fibroadenoma who underwent surgical excision in Denmark between 2011 and 2014, including regional differences in age, tumour size and year of surgery.</p><p><strong>Methods: </strong>In this nationwide registry-based cohort study, we identified all patients who underwent surgical excision of a fibroadenoma from 1 January 2011 to 31 December 2014, using the Danish National Register of Pathology. This registry provided information on age and region. Operation rates were calculated using population data from Statistics Denmark.</p><p><strong>Results: </strong>We identified 1,843 patients. The mean size of surgically removed fibroadenomas was 25.5 mm, and the mean age at surgery was 37 years. Patients > 50 years had a significantly higher proportion of small fibroadenomas (less-than 20 mm) removed than younger patients (p less-than 0.01). The overall operation rate was 20.6 per 100,000 women per year, highest in the 18-25-year age group (56.8 per 100,000 per year). Significant regional variation was found (p less-than 0.01), with the North Denmark Region having the highest operation rate (43.6 per 100,000 per year).</p><p><strong>Conclusions: </strong>Despite conservative management being recommended in Denmark during the study period, many fibroadenomas were surgically removed, and considerable regional variations were recorded. National guidelines are needed to ensure uniform, evidence-based treatment and reduce overtreatment.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>nr. SABN 3-3013-1306/1.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 10","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity of a thyrotoxicosis diagnosis code among women of fertile age.","authors":"Nanna Maria Uldall Torp, Signe Kirkegaard, Karoline Schack, Stine Linding Andersen","doi":"10.61409/A04250296","DOIUrl":"https://doi.org/10.61409/A04250296","url":null,"abstract":"<p><strong>Introduction: </strong>Graves' disease (GD) is the leading cause of hyperthyroidism in women of fertile age. Register-based studies rely on diagnostic codes; this study examined the validity of diagnosed thyrotoxicosis among women of fertile age in the Danish National Hospital Register (DNHR).</p><p><strong>Methods: </strong>All women in the North Denmark Region aged 18-45 years with a diagnosis of thyrotoxicosis (Tenth International Classification of Diseases: E05.0-05.9) in the DNHR from 2017-2018 were identified and medical records reviewed.</p><p><strong>Results: </strong>Among 263 women included, thyrotoxicosis was confirmed in 249 cases with a positive predictive value (PPV) of 94.7% (95% confidence interval (CI): 91.2-97.1%) for the diagnostic group (E05.0-05.9). Autoimmune hypothyroidism was the leading cause of misclassification. GD was the aetiology in 150 women, resulting in a PPV for GD of 57.0% (95% CI: 50.8-63.1%) in the diagnostic group (E05.0-05.9), increasing to 83.6% (95% CI: 76.4-89.3%) when restricted to women who were prescribed an antithyroid drug (ATD). The PPV for GD was highest when the specific diagnosis (DE05.0) was considered (PPV 91.1% (95% CI: 84.7-95.5%); however, 42 women with GD (28.0%) were first given a diagnosis of unspecified thyrotoxicosis (E05.9).</p><p><strong>Conclusions: </strong>The validity of thyrotoxicosis identified in the DNHR among women of fertile age was high. Results emphasise the importance of how subtypes of thyrotoxicosis are defined and show that the combined use of diagnoses and prescriptions of ATD is warranted to define GD.</p><p><strong>Funding: </strong>Novo Nordisk Foundation (grant no: NNF20OC0059465).</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 10","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delirium prevalence and screening in the Danish healthcare system.","authors":"Marie O Collet, Martin Shultz, Eva Laerkner, Charlotte Bjerg Sand Riis, Laura Krone Larsen, Kristine Mildahl Kjærgaard, Christina Emme, Iben Tousgaard, Bianca Bech, Anne-Dorte Krapper, Linette Thorn, Anne Højager Nielsen, Pernille Reck Miller, Camilla Grube Segers, Marie Damgaard Winther, Susanne Fischer, Sally Jakobsen, Tina Tang Fredenslund, Cecilie Fuglsbjerg, Helle Svenningsen","doi":"10.61409/A01250038","DOIUrl":"https://doi.org/10.61409/A01250038","url":null,"abstract":"<p><strong>Introduction: </strong>Delirium is an acute and severe syndrome, commonly occurring in elderly hospitalised or terminal patients, causing cognitive and psychotic symptoms due to somatic illness or medication. This study aimed to investigate the prevalence of delirium across hospitals and nursing homes in Denmark.</p><p><strong>Methods: </strong>This Danish cohort study, part of a global survey on March 15, 2023, examined delirium prevalence in hospitals and nursing homes. Data was collected on delirium screening practices, prevalence and staff experience.</p><p><strong>Results: </strong>Of 69 recruited hospitals and nursing homes, 66 participated, and 63 provided complete data for analysis. Participants included 79.4% nurses and 14.3% researchers. Delirium prevalence was 13.6% at 8 a.m. (general ward 9.7%, intensive care unit (ICU) 29.7%, emergency department 40.0% and nursing home 8.9%) and 13.9% at 8 p.m. (general ward 12.0%, ICU 19.8%, emergency department 27.2% and nursing home 10.8%) on March 15, 2023. The Confusion Assessment Method (CAM) was used by 23.8% of participants, and the confusion-assessment method for the ICU (CAM-ICU) was used by 28.6% of participants and was the most frequently used screening tool.</p><p><strong>Conclusions: </strong>On March 15, 2023, delirium prevalence in Denmark was 13.6% at 8 a.m. and 13.9% at 8 p.m. across 63 hospital departments and nursing homes. The CAM, brief CAM, and CAM-ICU were the most used assessment tools.</p><p><strong>Funding: </strong>There was no funding allocated to this study.</p><p><strong>Trial registration: </strong>The study was registered in the German Registry for Clinical Trials (DRKS00030002).</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 10","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"General practitioners' experiences of a data-driven quality development process.","authors":"Louise Hansen, Sarah Sofie Elmer Brandborg, Ulla Bjerre-Christensen, Trine Kjeldgaard Møller, Natasja Bjerre","doi":"10.61409/A12240912","DOIUrl":"https://doi.org/10.61409/A12240912","url":null,"abstract":"<p><strong>Introduction: </strong>Research shows that structured data use can optimise treatment in general practice clinics. This qualitative feasibility study evaluated a one-year intervention (DataSam) to assess whether increased use of population data can enhance type 2 diabetes treatment and workflows in general practice clinics.</p><p><strong>Methods: </strong>Audio-recordings of visits from 12 clinics at baseline, six and 12 months and end-of-intervention semi-structured interviews (n = 14) explored data use, workflow changes and implementation challenges. The data analysis was inspired by qualitative content analysis.</p><p><strong>Results: </strong>Clinics were positive about project activities and how structured data use enhanced management and patient overview while optimising treatment and prescribing practices. Most clinics experienced workflow improvements, such as nurses taking on more responsibilities and heightened staff skills, knowledge, job satisfaction and confidence in data-driven decision-making, medications and guidelines. However, approximately half of the clinics faced some implementation challenges, including technical issues and time constraints. Furthermore, some raised concerns about overtreatment, data misuse and de-prioritisation of other diagnoses.</p><p><strong>Conclusions: </strong>DataSam emphasises the potential of population data to optimise patient care, though further attention to implementation is needed.</p><p><strong>Funding: </strong>This study received an internal grant from Steno Diabetes. Centre Copenhagen.</p><p><strong>Trial registration: </strong>Registered as \"not required approval\" with the Regional Ethics Committee of the Capital Region (F-22073139).</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 10","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A survey of emergency physicians' prescription of piperacillin/tazobactam.","authors":"Sofie Damgaard Mortensen, Sanne Schjødt, Marianne Lisby","doi":"10.61409/A11240794","DOIUrl":"https://doi.org/10.61409/A11240794","url":null,"abstract":"<p><strong>Introduction: </strong>Piperacillin/tazobactam (Pip/Taz) is a broad-spectrum antibiotic, often prescribed in emergency departments (EDs). Excessive use of broad-spectrum antibiotics may lead to the rise of antimicrobial resistance, a concerning health issue. We investigated physicians' adherence to regional guidelines and their considerations when prescribing Pip/Taz in the ED.</p><p><strong>Methods: </strong>In this cross-sectional survey, a ten-item survey questionnaire was administered to ED physicians in five EDs from 10 January to 7 February 2024.</p><p><strong>Results: </strong>A total of 261 physicians employed in the ED were invited to participate in the survey. Among these, 144 physicians completed the survey, yielding a response rate of 55.2%. Based on the results, 25% were unaware of the regional guidelines on the prescription of Pip/Taz. In addition, over the past month, 25% had prescribed Pip/Taz in situations where regional guidelines recommended a narrow-spectrum antibiotic, primarily because of concerns regarding the patient's condition (74.3%); 30.6% of those who deviated from guidelines were consultants.</p><p><strong>Conclusions: </strong>This study found that a fourth of physicians in EDs were unaware of regional guidelines for prescribing Pip/Taz. Moreover, one in every four physicians purposely deviated from the recommended type of antibiotics, mainly because of concerns about the patient's clinical condition.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 10","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symptom profiles in long COVID compared to functional somatic disorder and the general population.","authors":"Jane Agergaard, Lisbeth Frostholm, Per Fink, Thomas Meinertz Dantoft, Berit Schiøttz-Christensen, Marie Weinreich Petersen","doi":"10.61409/A09240627","DOIUrl":"https://doi.org/10.61409/A09240627","url":null,"abstract":"<p><strong>Introduction: </strong>Long COVID, characterised by persistent symptoms following COVID-19, affects about 10% of individuals recovering from SARS-CoV-2. The overlap of symptoms described in long COVID and functional somatic disorder (FSD) raises questions about shared pathophysiology. This report compares the prevalence and profiles of physical symptoms among patients with long COVID, patients with FSD and the general population.</p><p><strong>Methods: </strong>Data from a cohort of patients with long COVID referred for diagnostics, a cohort of patients seen in a regional clinic for FSD and individuals from the general population were used. Questionnaires, including the bodily distress syndrome checklist, were used to assess physical symptoms.</p><p><strong>Results: </strong>A total of 436 patients with long COVID, 264 patients with FSD and 9,656 individuals from the general population were included. A lower prevalence of symptoms was observed in patients with long COVID than in patients with FSD. However, the prevalence of symptoms in patients with long COVID remained higher than in the general population. In patients with long COVID, dominant symptoms were from the general symptoms (GS) cluster (concentration difficulties, fatigue, headache, memory problems) and muscle pain. Additionally, 11% met the criteria for multi-organ FSD, exhibiting a similar symptom profile to patients with FSD.</p><p><strong>Conclusions: </strong>A total of 11% of long COVID patients had a symptom profile similar to that of patients with multi-organ FSD. GS, including fatigue and muscle pain, were common. These findings highlight the need for prospective studies to identify patients with similar symptoms, pathogenesis and treatment options.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 10","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Danish version of the Dizziness Handicap Inventory - translation and validation.","authors":"Helle Elisabeth Agger-Nielsen, Signe Fiil Bønløkke, Hanne Owen, Therese Ovesen","doi":"10.61409/A12240910","DOIUrl":"https://doi.org/10.61409/A12240910","url":null,"abstract":"<p><strong>Introduction: </strong>The Dizziness Handicap Inventory (DHI) is a widely used patient-reported outcome measure assessing the impact of dizziness on daily life. A Danish version (DHI-DK) was developed to facilitate its use in Danish-speaking populations.</p><p><strong>Methods: </strong>The DHI was translated into Danish following standard cross-cultural adaptation procedures. The psychometric properties of the DHI-DK were evaluated in a sample of 100 patients with dizziness. Internal consistency was assessed using Cronbach's alpha, test-retest reliability with intraclass correlation coefficients (ICCs), and construct validity through correlations with the visual analogue scale (VAS).</p><p><strong>Results: </strong>The DHI-DK demonstrated high internal consistency (Cronbach's alpha = 0.88) and excellent test-retest reliability (ICC = 0.95). A strong correlation was observed between DHI-DK and VAS scores (r = 0.60, p less-than 0.001), supporting construct validity.</p><p><strong>Conclusions: </strong>The DHI-DK is a reliable and valid instrument for assessing the self-perceived handicap due to dizziness in Danish-speaking patients. It is suitable for use in both clinical practice and research settings.</p><p><strong>Funding: </strong>This study received no external funding.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 10","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}