Jakob Ohm Oreskov, Cecilie Nørregaard Albertsen, Claus Høgdall, Anne Weng Ekmann-Gade, Sarah Mejer Sørensen, Karsten Dromph, Algirdas Markauskas, Pernille Tine Jensen, Tine Henrichsen Schnack
{"title":"Register-based algorithm to detect post-operative complications in patients with ovarian cancer.","authors":"Jakob Ohm Oreskov, Cecilie Nørregaard Albertsen, Claus Høgdall, Anne Weng Ekmann-Gade, Sarah Mejer Sørensen, Karsten Dromph, Algirdas Markauskas, Pernille Tine Jensen, Tine Henrichsen Schnack","doi":"10.61409/A12240907","DOIUrl":"https://doi.org/10.61409/A12240907","url":null,"abstract":"<p><strong>Introduction: </strong>Epithelial ovarian cancer (OC) is the most fatal gynaecological cancer. The use of extensive surgical procedures implies the potential severity of post-operative complications. In Denmark, registration of complications has changed from manual database registration to data transfer from medical records to the Danish National Patient Registry (NPR). This study examines whether a new complication algorithm based on NPR data may be used to identify 30-day post-operative complications among patients with advanced stage IIIC-IV OC.</p><p><strong>Methods: </strong>Complications were graded according to Clavien-Dindo (CD). The algorithm was validated in a cohort undergoing surgery at the OUH, between 1 January 2007 and 31 December 2012. The CD grades were sub-grouped into mild (CD 0-2) and severe (CD 3-5) complications for sub-analyses.</p><p><strong>Results: </strong>A total of 330 patients were included. The overall sensitivity (SN) and specificity (SP) of the algorithm (CD 0-5) were 56.4% (95% confidence interval (CI): 48.0-65.0%) and 92.4% (95% CI: 86.5-93.0%), respectively, with an overall kappa coefficient (κ) of 0.43. For severe complications (CD 3-5), the algorithm had an SN of 74.2% (95% CI: 67.4-83.6%) and an SP of 97.4% (95% CI: 95.5-99.4%), with a κ of 0.65.</p><p><strong>Conclusions: </strong>The algorithm had a moderate SN and a high SP with substantial agreement regarding severe complications. A standardised registration of complications in the NPR will likely improve the algorithm's performance.</p><p><strong>Funding: </strong>The Danish Clinical Quality Program DKK 200,000.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 7","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of sialendoscopy for salivary gland occlusions.","authors":"Benjamin Seddighi, Therese Ovesen, Ali Abood","doi":"10.61409/A11240783","DOIUrl":"https://doi.org/10.61409/A11240783","url":null,"abstract":"<p><strong>Introduction: </strong>Minimally invasive procedures using sialendoscopy have emerged as a safer alternative to traditional interventions for non-neoplastic occlusions of the salivary glands. To illuminate the procedure's efficacy, demographics and outcomes of patients undergoing sialendoscopies are presented.</p><p><strong>Methods: </strong>Retrospective cohort study. Medical files of patients who underwent sialendoscopy at Gødstrup Hospital from 27 October 2018 to 30 June 2023 were reviewed. Surgical success was defined as complete symptom relief and no complications within a three-month follow-up, while surgical failure was defined as any symptoms or complications within the follow-up period.</p><p><strong>Results: </strong>Complete sialendoscopy was performed in 110 patients of whom 94 attended a follow-up after three months. The mean age at the time of surgery was 44.2 years (95% confidence intervals (CI): 40.3-48.1), and 48.2% were male. Surgical success was achieved in 53 cases with follow-up (56.4% (95% CI: 46.4-66.4%)). Additionally, symptom relief was achieved in another 23 cases, meaning that a total of 76 patients benefited from the procedure (80.9% (95% CI: 72.9-88.8)). Patients with sialolithiasis had a significantly higher surgical success rate, while patients with stenosis had a significantly lower surgical success rate.</p><p><strong>Conclusions: </strong>The results confirm that sialendoscopy is a safe, effective and feasible procedure for diagnosing and treating non-neoplastic occlusions of the salivary gland. Our findings indicate better results for patients with sialoliths than those with stenosis.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 6","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Trine Kjeldgaard Møller, Martin Riis Johansen, Ulla Bjerre-Christensen, Peter Lommer Kristensen
{"title":"Using type 2 diabetes population data in general practice may affect workflow and clinical outcomes.","authors":"Trine Kjeldgaard Møller, Martin Riis Johansen, Ulla Bjerre-Christensen, Peter Lommer Kristensen","doi":"10.61409/A11240795","DOIUrl":"https://doi.org/10.61409/A11240795","url":null,"abstract":"<p><strong>Introduction: </strong>Studies have demonstrated that electronic feedback utilising patient data from general practice may effectively promote adherence to treatment guidelines, making it a valuable tool for quality improvement. Therefore, we aimed to explore the effect of data-driven quality improvement in general practice on clinical outcomes for people with type 2 diabetes.</p><p><strong>Methods: </strong>A total of 15 general practitioners participated in a quality development process with visits from an organisational advisor. Six other control clinics did not participate in the quality process. Diabetes-related data were gathered at baseline and after six and 12 months.</p><p><strong>Results: </strong>The intervention improved adherence to guidelines. We observed between-group effects for the proportion of annual control within 12 months, HbA1c, low-density lipoprotein (LDL) and estimated glomerular filtration rate measurements, the proportion of patients with LDL less-than 2.5 mmol/l and a reduction in patients with ischaemic heart disease and no secondary prevention treatment.</p><p><strong>Conclusions: </strong>The intervention may represent an easy-to-implement solution to creating workflow routines by comprehensively analysing the patient population at the clinic level. However, selection bias may influence the results.</p><p><strong>Funding: </strong>The study was funded by Steno Diabetes Centre Copenhagen.</p><p><strong>Trial registration: </strong>Regional ethics committee of the capital region (F-22073139).</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 6","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emma Helledie, Kristoffer Marsaa, Tina Lyngstroem, Mogens Groenvold, Per Sjoegren, Lise Nottelmann, Torben Strodl Andersen, Anette Hygum, Jette Paerregaard, Dorte Lange Hoest, Henrik Anker Nielsen, Mette Kelstrup Hallas, Irene J Higginson, Mette Asbjoern Neergaard
{"title":"Development of a national strategy for palliative care.","authors":"Emma Helledie, Kristoffer Marsaa, Tina Lyngstroem, Mogens Groenvold, Per Sjoegren, Lise Nottelmann, Torben Strodl Andersen, Anette Hygum, Jette Paerregaard, Dorte Lange Hoest, Henrik Anker Nielsen, Mette Kelstrup Hallas, Irene J Higginson, Mette Asbjoern Neergaard","doi":"10.61409/A12240872","DOIUrl":"https://doi.org/10.61409/A12240872","url":null,"abstract":"<p><strong>Introduction: </strong>In 2020, the Danish National Audit Office (Rigsrevisionen) criticised the Danish palliative care (PC) provision. The Board of the Danish Association for Palliative Medicine (DSPaM) recognised an urgent need for a national strategy to improve PC in Denmark. The Board wished to develop a strategy which ensured acceptance and legitimation internationally and within the DSPaM. The aim of this study was to describe the development of the DSPaM 'National strategy of palliative care for patients with life-threatening diseases'.</p><p><strong>Methods: </strong>The Cicely Saunders International (CSI) action plan, 'You matter because you are you, an action plan for better palliative care,' seemed applicable because of its extensive, evidence-based content. A thorough translation and cultural adaptation were followed by group discussions and a Delphi process among DSPaM members.</p><p><strong>Results: </strong>The Delphi process underwent eight editions before the final version was approved by the DSPaM Board in January 2024. A total of 36% of the members participated in the group discussions in January 2022. The response rates were 43% in the first and 62.8% in the second survey, with a final average member agreement of 92.7%. The main differences were that the CSI action plan mentions COVID-19 pandemic and patient empowerment, whereas the Danish strategy document refers to socially vulnerable patients.</p><p><strong>Conclusions: </strong>A Danish strategy document for PC was developed through a Delphi process involving the DSPaM members. The Danish strategy document was approved by a large majority of DSPaM members, thus providing a solid ground for a common national strategy for PC in Denmark.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 6","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Post-operative nutritional practice in emergency laparotomy.","authors":"Jannick Brander Hansen, Bente Hegstad, Nadia Boujida, Dunja Kokotovic Gellert-Kristensen, Jakob Burcharth","doi":"10.61409/A11240841","DOIUrl":"https://doi.org/10.61409/A11240841","url":null,"abstract":"<p><strong>Introduction: </strong>Post-operative nutrition in emergency abdominal surgery can be challenging, and evidence on nutritional management in this population needs to be included in guidelines. This study aimed to describe the nutritional practice after emergency laparotomy at a university hospital and compare the routine practice to current guidelines.</p><p><strong>Methods: </strong>This was a single-centre retrospective cohort study of consecutive patients undergoing emergency laparotomy from August 2021 to August 2022. Patients transferred to other hospitals or non-surgical wards were excluded. Nutritional data during admission were assessed daily from post-operative day (POD) 1 up to POD 30.</p><p><strong>Results: </strong>A total of 231 patients were included; 118 (51.1%) were male, and the median age was 71 years (IQR: 58-79 years). Bowel obstruction was found in 144 (62.3%) of patients. The median length of stay was eight days (IQR: 5-14 days). Any oral intake on POD 1 was achieved by 113 (48.9%), increasing to 203 (87.9%) on POD 5. Nasogastric tubes and dietary restrictions were standard in patients not achieving oral intake on POD 1. Parenteral nutrition was used in 66 (28.6%) patients; the median time from surgery to initiation of parenteral nutrition was four days (IQR: 3-6.75 days), and the median duration of parenteral nutrition was seven days (IQR: 5-15 days).</p><p><strong>Conclusions: </strong>Early oral intake after major emergency abdominal surgery was only achieved in half of the patients, and current practice deviates from current guidelines. Special considerations should be made in patients undergoing emergency laparotomy as their post-operative condition differs from that of elective cases.</p><p><strong>Funding: </strong>This study was supported by the Novo Nordisk Foundation (grant number NNF22OC0079459). The Novo Nordisk Foundation was not involved in study design, data collection, analysis, interpretation or writing.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 6","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gosia F Nielsen, Susanne Reventlow, Gritt Overbeck, Mads Kristensen
{"title":"Cross-sectoral collaboration of mental health problems in children and adolescents.","authors":"Gosia F Nielsen, Susanne Reventlow, Gritt Overbeck, Mads Kristensen","doi":"10.61409/A05240353","DOIUrl":"https://doi.org/10.61409/A05240353","url":null,"abstract":"<p><strong>Introduction: </strong>A growing number of children and adolescents (CA) suffer from mental health problems. To provide the necessary investigation and care, collaboration between general practitioners (GPs) and the municipality is essential, but often challenging. This study aimed to identify factors influencing intersectoral collaboration between general practice and municipalities when treating CA with mental health problems and to propose improvements to this collaboration.</p><p><strong>Methods: </strong>We conducted interviews with seven GPs and three municipal employees (MEs). The data were analysed with inspiration from thematic analysis. The results were framed within Gittell's theory of relational coordination.</p><p><strong>Results: </strong>GPs and MEs expressed frustration and challenges encountered when working with CA due to inefficient intersectoral collaboration. Many GPs expressed a need for better communication with municipal authorities or child psychiatry departments. MEs also experienced challenges related to this collaboration. Successful collaboration appeared when dedicated individuals from both sectors actively worked for improvements. Key factors identified for enhancing collaboration included personal knowledge, regular contact, awareness of activities in the other sector and improved communication channels.</p><p><strong>Conclusions: </strong>We propose enhanced cross-sectoral communication, routine information exchange and further development of digital tools to improve collaboration. Formalising collaboration through specific agreements is also recommended.</p><p><strong>Funding: </strong>\"PLU-fonden\" and \"Sara Krabbes Legat\" TRIAL REGISTRATION. Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 6","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Daoud, Jens Fedder, Hanne Lindegaard, Vibeke Mortensen, Christian Laursen
{"title":"The need for early clinical exposure in medical education.","authors":"Mohammed Daoud, Jens Fedder, Hanne Lindegaard, Vibeke Mortensen, Christian Laursen","doi":"10.61409/A08240570","DOIUrl":"https://doi.org/10.61409/A08240570","url":null,"abstract":"<p><strong>Introduction: </strong>Anxiety among medical students is highly prevalent and may negatively impact students' future practice. Transitioning from the pre-clinical to the clinical phase often presents considerable challenges. Early clinical exposure has been identified as beneficial in easing this transition. Most medical schools in Scandinavia already include a few weeks of exposure. Even so, student distress remains high. The study aimed to assess the need for more clinical exposure during the Bachelor of Science (BSc) programme in medicine based on students' subjective needs.</p><p><strong>Methods: </strong>This cross-sectional study employed a non-probability sampling method to include medical students enrolled in the Master of Science (MSc) programme at the University of Southern Denmark. A self-administered questionnaire was designed to explore medical students' self-reported needs and attitudes towards the BSc programme. Descriptive and inferential statistics were used to summarise and assess the data.</p><p><strong>Results: </strong>Among the 120 students included, 90% perceived the clinical exposure during the BSc programme as insufficient. Furthermore, 68% felt inadequate in their understanding of a physician's clinical role, and 87% felt inadequacy in their understanding of the work-life balance within the profession upon completing the BSc degree. The estimated response rate was 13%.</p><p><strong>Conclusions: </strong>The findings suggest a subjective need for more clinical exposure in the BSc programme. However, the impact of additional clinical exposure on student distress remains unclear.</p><p><strong>Funding: </strong>The authors did not receive any funding or support.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 6","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kamran Abbasi, Parveen Ali, Virginia Barbour, Marion Birch, Inga Blum, Peter Doherty, Andy Haines, Ira Helfand, Richard Horton, Kati Juva, Jose F Lapena, Robert Mash, Olga Mironova, Arun Mitra, Carlos Monteiro, Elena N Naumova, David Onazi, Tilman Ruff, Peush Sahni, James Tumwine, Carlos Umaña, Poul Yonga, Chris Zielinski
{"title":"Ending nuclear weapons, before they end us.","authors":"Kamran Abbasi, Parveen Ali, Virginia Barbour, Marion Birch, Inga Blum, Peter Doherty, Andy Haines, Ira Helfand, Richard Horton, Kati Juva, Jose F Lapena, Robert Mash, Olga Mironova, Arun Mitra, Carlos Monteiro, Elena N Naumova, David Onazi, Tilman Ruff, Peush Sahni, James Tumwine, Carlos Umaña, Poul Yonga, Chris Zielinski","doi":"10.61409/A300014","DOIUrl":"https://doi.org/10.61409/A300014","url":null,"abstract":"","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 6","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Normative data on a reliable and sensitive test of gustatory function.","authors":"Laura Marie Aalkjær, Alexander Wieck Fjældstad","doi":"10.61409/A09240590","DOIUrl":"https://doi.org/10.61409/A09240590","url":null,"abstract":"<p><strong>Introduction: </strong>Our sense of taste plays a key role in eating and drinking, guiding behaviour through warning and pleasure signalling. Taste dysfunction has severe consequences for patients. Reliable gustatory testing is relevant for researchers and clinicians, emphasising the need for reproducible measuring methods. This study aimed to provide normative data on the Taste-Drop-Test (TDT), which is already used in clinical and research settings.</p><p><strong>Methods: </strong>The TDT was administered to 424 healthy participants and 134 patients with gustatory dysfunction. The test consisted of liquid concentrations of four basic tastes: acidic, sweet, salty and bitter. After application, a test score was calculated for each individual.</p><p><strong>Results: </strong>In the healthy participants, a significant correlation was found between TDT score and olfactory function. Furthermore, a significant positive correlation was found for superior taste function for younger age and female sex. The cut-off value based on the tenth percentile in the healthy participants was 6.25.</p><p><strong>Conclusions: </strong>The TDT can distinguish between normo- and hypogeusia. We recommend using the TDT to researchers and clinicians when an accurate measurement of gustatory function is warranted.</p><p><strong>Funding: </strong>This project received no specific funding. Alexander Wieck Fjældstad is partially funded by the VELUX Foundation for other projects.</p><p><strong>Trial registration: </strong>The Central Denmark Region Ethics Committee approved the study (42832), which was conducted in consistency with the Declaration of Helsinki Ethical Principles of Medical Research.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 5","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rikke Brink Petersen, Christina Damgaard Buch, Christian Faergemann, Tine Nymark
{"title":"Bone deformities with hereditary multiple osteochondromas.","authors":"Rikke Brink Petersen, Christina Damgaard Buch, Christian Faergemann, Tine Nymark","doi":"10.61409/A11230696","DOIUrl":"https://doi.org/10.61409/A11230696","url":null,"abstract":"<p><strong>Introduction: </strong>Hereditary multiple osteochondromas (HMO) is a genetic skeletal disorder caused by defects in exostosin glycosyltransferase 1 (EXT1) or 2 (EXT2) genes. It develops mainly in the growth period and causes multiple osteochondromas (OC) in the physis of the long bones, leading to discomfort and deformities. This study aimed to investigate the anatomical distribution of OC, the frequency of deformities of the lower limbs, scoliosis and surgeries performed in a cohort of patients with HMO at the time of their enrolment in a regional surveillance programme.</p><p><strong>Methods: </strong>The study population included HMO patients from the Centre of Heritable and Complex Diseases (CAKS) in the Region of Southern Denmark. Information on surgical procedures and age at the time of diagnosis was obtained from medical records, while deformities were evaluated on early-onset scoliosis (EOS) scans from time of enrolment in the CAKS.</p><p><strong>Results: </strong>A total of 54 patients were included and 44 patients (82%) had an EOS scan. All except one (98%) HMO patient had OC in the knees at the time of their EOS scan. A total of 12 patients (27%) had leg length discrepancy, 30 (68%) had genu varum or valgum and 13 (30%) had scoliosis. The HMO patients had undergone a median of 2.0 (0-14) surgeries, where a median of four (1-23) OC were removed, mostly in the lower limb (68%).</p><p><strong>Conclusions: </strong>The majority of HMO patients in this cohort suffered from major anatomical burdens, leading to multiple surgeries and deformities. We suggest that a programme, such as the CAKS surveillance programme, may be beneficial to screening and follow-up of OC and deformities in patients with HMO.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 5","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}