Janne Sorensen, Hejdi Abdelhamid, Julia Kadin Funge
{"title":"Health professionals' access to diversity training across Denmark.","authors":"Janne Sorensen, Hejdi Abdelhamid, Julia Kadin Funge","doi":"10.61409/A07240472","DOIUrl":"https://doi.org/10.61409/A07240472","url":null,"abstract":"<p><strong>Introduction: </strong>Health disparities exist between migrants and ethnic minorities (MEM) and the majority population in Europe and Denmark. As diversity increases, delivering healthcare appropriate to MEM is essential. Training health professionals (HP) in diversity competence (DC) prepares them for a diverse society and helps address health disparities among MEM. The study aims to investigate which educational activities exist regarding DC training across sectors in Denmark.</p><p><strong>Methods: </strong>An email survey was sent to all health education programmes, municipalities, regions (including hospitals), healthcare worker unions, medical societies/associations, the Ministry of Health and the Danish Health Authority. Among the 295 institutions contacted, 148 responded. Ten surveys were excluded, yielding a dataset of 138 surveys and a response rate of 46.8%. Data were collected between 21 February and 12 May 2022.</p><p><strong>Results: </strong>All but one participating health education program included some level of DC in their curriculum. However, few institutions provided DC training for teaching staff. DC training in municipalities and regions varies, but most agree that it is relevant. Some municipalities that do not offer DC training to HPs attribute this to a lack of MEM citizens.</p><p><strong>Conclusions: </strong>Most health professionals lack adequate access to diversity competence training. Regions, municipalities and educational institutions should provide continuing medical education for healthcare workers in this area.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 4","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher Bach Sørensen, Anders Gram-Hanssen, Jacob Rosenberg, Jason Joe Baker
{"title":"Danish validation of the Abdominal Hernia-Q.","authors":"Christopher Bach Sørensen, Anders Gram-Hanssen, Jacob Rosenberg, Jason Joe Baker","doi":"10.61409/A06240434","DOIUrl":"https://doi.org/10.61409/A06240434","url":null,"abstract":"<p><strong>Introduction: </strong>Ventral hernias significantly impact patients' quality of life. It is essential to recognise this when creating a treatment plan and conducting studies that compare interventions. The Abdominal Hernia-Q is a meticulously validated questionnaire that focuses on patient-reported outcomes. However, at the time of this study, no Danish version was available. Therefore, this study aimed to develop a Danish translation of the Abdominal Hernia-Q.</p><p><strong>Methods: </strong>The translation of the questionnaire followed a comprehensive process, including forward-backwards translation, expert committee review and pretesting to ensure face validity. We included ten patients for pretesting. The inclusion criteria were > 18 years of age and a history of ventral hernia repair. The exclusion criteria were the inability to speak or read Danish.</p><p><strong>Results: </strong>A Danish version of the Abdominal Hernia-Q was successfully developed. This process revealed a few minor discrepancies between translators, which were resolved through discussion. Pretesting identified three issues: one unspecified and two minor cultural issues. All issues were addressed and corrected.</p><p><strong>Conclusion: </strong>A validated Danish version of the Abdominal Hernia-Q is now available for use by clinicians and researchers, having undergone rigorous pretesting for face validity.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>This study was approved by the Danish Data Protection Agency (p-2023-15228).</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 4","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martin Skott, Tina L Leunbach, Gitte Møller Hvistendahl, Yazan F Rawashdeh
{"title":"Management of complications after hypospadias repair during childhood.","authors":"Martin Skott, Tina L Leunbach, Gitte Møller Hvistendahl, Yazan F Rawashdeh","doi":"10.61409/A08240506","DOIUrl":"https://doi.org/10.61409/A08240506","url":null,"abstract":"<p><strong>Methods: </strong>This study aims to describe the presenting complaints, clinical findings and management strategies in men with a history of prior hypospadias surgery. Men aged 15 years or older, referred with complaints related to hypospadias, were identified through the electronic patient record system. Data were collected over a ten-year period.</p><p><strong>Results: </strong>Of 201 referrals, 136 men had a history of hypospadias surgery, with a median age at referral of 33 years (range: 15-72). The most common presenting complaints were urethral stricture (n = 63) or meatal stenosis (n = 14), which were more frequently observed in older patients. Other presenting complaints were urethrocutaneous fistula (n = 24), preputial problems (n = 8) and penile curvature (n = 7). An additional 20 men presented with various complaints such as spilt urine stream, episodes of haematuria, anejaculation or coital pain. Management strategies included reconstructive procedures (e.g., single or staged urethroplasty), minor procedures (such as Nesbit procedure or fistula closure), endoscopic interventions (urethral dilation or urethrotomy) or counselling.</p><p><strong>Conclusions: </strong>Complaints following previous hypospadias repair are present across the entire adult age span. Therefore, caregivers of young boys must be informed following hypospadias surgery to seek medical evaluation whenever hypospadias-related complications are suspected, even decades after reconstruction.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 4","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emilie Gertrud Skjoldemose Lerche-Jørgensen, Jacob Rosenberg, Eva Gravesen
{"title":"Incidence and clinicopathological features of incidental gallbladder cancer.","authors":"Emilie Gertrud Skjoldemose Lerche-Jørgensen, Jacob Rosenberg, Eva Gravesen","doi":"10.61409/A11240787","DOIUrl":"https://doi.org/10.61409/A11240787","url":null,"abstract":"<p><strong>Introduction: </strong>Annually, more than 9,000 cholecystectomies are performed in Denmark. All gallbladders are submitted for histological examination to rule out preoperatively undetected gallbladder cancer. The histological examination at the Department of Pathology is costly. Therefore, it is relevant to investigate whether adopting a selective approach in which only selected gallbladders are submitted for histological examination is reasonable.</p><p><strong>Methods: </strong>All cholecystectomies submitted for histological examination at the Department of Pathology at Herlev Hospital from 1 January 2014 to 31 December 2023 were included in the study. In cases of gallbladder cancer, the results of the preoperative diagnostic imaging, intraoperative findings and the macroscopic examination at the Department of Pathology were systematically reviewed.</p><p><strong>Results: </strong>In total, 9,698 gallbladders were included in the study. Across all patients, the incidence of gallbladder cancer was 0.29%, with a total of 28 cases being identified. In patients ≤ 60 years, the incidence of gallbladder cancer was 0.08%, whereas the incidence of gallbladder cancer was 0.67% in patients > 60 years. Among the 28 cases of gallbladder cancer, the surgeon noted macroscopic changes in 27 cases, while such changes were observed in all cases during the macroscopic examination at the Department of Pathology.</p><p><strong>Conclusion: </strong>The study supports implementing a selective approach to histopathological examination of the gallbladder after cholecystectomy but also emphasises the need for a thorough macroscopic examination.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 4","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter regarding: \"Arterial pH and short-term mortality in adult non-traumatic acute patients\".","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This is a letter to the editor on the article \"Arterial pH and short-term mortality in adult non-traumatic acute patients\" Dan Med J 2025;72(1):A06240407. doi: 10.61409/A06240407.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 4","pages":"1"},"PeriodicalIF":1.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marius Moen Christiansen, Ameer Jamal Iversen, Annmarie Touborg Lassen, Isik Somuncu Johansen, Flemming Schønning Rosenvinge, Michael Dan Arvig
{"title":"Reply to: Letter regarding \"Arterial pH and short-term mortality in adult non-traumatic acute patients\".","authors":"Marius Moen Christiansen, Ameer Jamal Iversen, Annmarie Touborg Lassen, Isik Somuncu Johansen, Flemming Schønning Rosenvinge, Michael Dan Arvig","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Letter regarding \"Arterial pH and short-term mortality in adult non-traumatic acute patients\" Dan Med J 2025;72(1):A06240407. doi: 10.61409/A06240407.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 4","pages":"1"},"PeriodicalIF":1.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biomarkers in dementia disorders - a narrative review.","authors":"Steen Gregers Hasselbalch","doi":"10.61409/A09240634","DOIUrl":"10.61409/A09240634","url":null,"abstract":"<p><p>With the introduction of specific or unspecific biomarkers, the diagnosis of dementia disorders has changed from a purely clinical to a biological construct. This review presents biomarkers for the most common neurodegenerative disorders. Specific biomarkers for misfolded proteins have been developed for Alzheimer's disease and dementia with Lewy bodies. Unspecific biomarkers for neurodegeneration, synaptic dysfunction and neuroinflammation may also be helpful in diagnosing or staging dementia disorders.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 3","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oliver Wagner Ulf Nielsen, Mikkel Oliver Skov Risom, Hans Linde Nielsen, Jacob Bodilsen, Henrik Nielsen
{"title":"Nephrotoxicity associated with short-term gentamicin therapy in community-acquired bacteraemia: risk of nephrotoxicity.","authors":"Oliver Wagner Ulf Nielsen, Mikkel Oliver Skov Risom, Hans Linde Nielsen, Jacob Bodilsen, Henrik Nielsen","doi":"10.61409/A08240568","DOIUrl":"10.61409/A08240568","url":null,"abstract":"<p><strong>Introduction: </strong>Hesitancy towards the use of aminoglycosides persists among clinicians due to the perceived risk of nephrotoxicity.</p><p><strong>Methods: </strong>This retrospective cohort study included adults with community-acquired bacteraemia and no pre-existing renal failure. The patients were divided into two groups matched 1:1 by age (± 5 years): 1) patients treated with short-term (≤ 3 days) once-daily gentamicin within 24 hours of admission and 2) non-gentamicin-treated patients. The primary endpoint was an increase in plasma creatinine levels of ≥ 40 µmol/l from baseline. Cause-specific Cox regression was used to compute hazard ratios (HR) with 95% confidence intervals (CI) for prognostic factors of acute kidney injury (AKI) and death.</p><p><strong>Results: </strong>A total of 310 adults with bacteraemia were included, among whom 159 (49%) were treated with gentamicin and 151 (51%) with other antibiotics. No significant between-group differences were observed in sex distribution, comorbidities, biochemical variables and vital signs at admission. In the gentamicin-exposed group, 11 (7%) patients developed AKI compared with 12 (8%) patients in the non-exposed group. Gentamicin was neither associated with increased risk of AKI (HR = 0.86; 95% CI: 0.38-1.96) nor with 30-day mortality (HR = 0.73; 95% CI: 0.38-1.41) compared with other antibiotic regimens.</p><p><strong>Conclusions: </strong>Our study showed no increase in the risk of developing AKI and no increase in all-cause mortality in patients treated with short-term once-daily gentamicin for community-acquired bacteraemia compared with other antibiotic regimens.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 3","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cara Manmeet Bhuller, Michael Bau Mortensen, Henriette Engberg, Claus Wilki Fristrup
{"title":"Validity of the Pancreatic Cancer Registry in Southern Denmark.","authors":"Cara Manmeet Bhuller, Michael Bau Mortensen, Henriette Engberg, Claus Wilki Fristrup","doi":"10.61409/A08240545","DOIUrl":"10.61409/A08240545","url":null,"abstract":"<p><strong>Introduction: </strong>The Danish Pancreatic Cancer Database (DPCD) uses data from the Danish National Patient Registry (DNPR) and includes patients with pancreatic carcinomas, duodenal and ampullary cancers. Due to the aggressive nature of pancreatic cancer, some patients never receive diagnostic work-up at a hepato-pancreatico-biliary centre. The aim of this study was to explore the validity of the registration of the pancreatic cancer diagnosis for patients living in the Region of Southern Denmark reported in the DNPR but not included in the DPCD.</p><p><strong>Methods: </strong>This study is a descriptive analysis of a historical cohort of patients registered with a diagnosis of pancreatic cancer (DC 25.0-25.9, DC 24.1, DC 17.0, excluding DC 25.4) from 1 July 2019 to 30 June 2022, in the DNPR but with no registration in the DPCD.</p><p><strong>Results: </strong>We identified 155 patients with a relevant diagnosis in the DNPR who were not included in the DPCD. A total of 62 patients (40%) represented potentially valid cases of pancreatic cancer, whereas 73 patients (47%) had pNET and 20 patients (13%) had an entirely different diagnosis. Only seven patients (11%) of the potentially valid pancreatic cancer group and 4.5% of the total study cohort had a histology-verified diagnosis of pancreatic cancer. The DNPR contained (93/944) 10% with an incorrect diagnosis of pancreatic cancer and 6% with an uncertain diagnosis.</p><p><strong>Conclusions: </strong>This study demonstrates a high level of completeness for the DPCD in the Region of Southern Denmark. Invalid registration of the pancreatic cancer diagnosis is an important limitation in using the DNPR, which is the only data source for identifying patients with pancreatic cancer in Denmark.</p><p><strong>Funding: </strong>None.</p><p><strong>Trial registration: </strong>Not relevant.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 3","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Monitoring and reporting of adverse effects in weight loss trials in children.","authors":"Catja Alcoat, Rasmus Køster-Rasmussen","doi":"10.61409/A05240327","DOIUrl":"10.61409/A05240327","url":null,"abstract":"<p><p>We investigated if the studies included in a Cochrane Review had examined and reported adverse effects of lifestyle intervention for weight loss in children. We evaluated each of the 70 RCTs included. A total of 67 trials (96%) did not report a method for monitoring adverse effects. Six trials (9%) reported physical adverse events. One trial reported a \"negative effect on children's feelings\". None of the 70 studies examined for or reported social adverse effects. In conclusion, only a few studies of lifestyle intervention for weight loss in children examined for potential harm, and 96% did not meet the present-day standard for reporting trials as described in the CONSORT statement.</p>","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 3","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}