Danish medical journal最新文献_第10页

Open surgical repair of hip abductor tendon tears. 髋关节内收肌腱撕裂的开放式手术修复。

IF 1.6 4区医学

Danish medical journal Pub Date : 2024-02-08 DOI: 10.61409/A08230526

Jeppe Lange, Bent Lund, Kasper Spoorendonk, Marie Bagger Bohn

{"title":"Open surgical repair of hip abductor tendon tears.","authors":"Jeppe Lange, Bent Lund, Kasper Spoorendonk, Marie Bagger Bohn","doi":"10.61409/A08230526","DOIUrl":"10.61409/A08230526","url":null,"abstract":"Introduction: Tendinopathy and tendon tears of the gluteus medius and/or minimus (GMM) insertion at the greater trochanter are increasingly recognised internationally as a cause of recalcitrant lateral hip pain (LHP). The purpose of this study was to report the first Danish results of open surgical repair of GMM tears in female patients.Methods: In this retrospective observational study, we included 67 women (68 hips) with a mean (95% confidence interval (CI)) age of 59 (56-61) years who underwent open GMM repair between September 2018 and June 2022. All cases had magnetic resonance imaging before surgery. Pre-, three- and 12-month post-operative testing included LHP (numerical rating scale 0-10), Copenhagen Hip and Groin Outcome Score (HAGOS), Oxford Hip Score (OHS), the EuroQol-Visual Analogue Scale (EQ-VAS) and the Global Rating of Change score (GROC). Responses on GROC were considered successful if patients scored \"moderately better\" to \"very much better\". Function of the lower limbs was assessed by the 30-second Chair-Stand-Test (CST).Results: From pre-testing to 12-month follow-up, LHP at rest and during activity decreased significantly, all HAGOS subgroups improved by 27-35 points, the OHS improved from 22 to 35 points, the EQ-VAS improved from 52 to 72 points and the mean (95% CI) number of repetitions in the CST improved by 2.4 (1.4-3.3). Success on the GROC was reported by 79% of the patients.Conclusion: Open surgical repair of GMM tendon tears in women produced statistically significant improvements in patient-reported outcomes at one-year follow-up.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"71 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140038899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infrequent transition to direct oral anticoagulants in patients with cancer. 癌症患者很少转用直接口服抗凝剂。

IF 1.6 4区医学

Danish medical journal Pub Date : 2024-01-25 DOI: 10.61409/A05230278

Nina Nouhravesh, Caroline Sindet-Pedersen, Maja Hellfritzsch, Ali Akil Al-Alak, Thomas Kümler, Erik L Grove, Morten Lamberts

{"title":"Infrequent transition to direct oral anticoagulants in patients with cancer.","authors":"Nina Nouhravesh, Caroline Sindet-Pedersen, Maja Hellfritzsch, Ali Akil Al-Alak, Thomas Kümler, Erik L Grove, Morten Lamberts","doi":"10.61409/A05230278","DOIUrl":"10.61409/A05230278","url":null,"abstract":"Introduction: Pharmacokinetic drug-drug interactions (DDIs) are challenging aspects of direct oral anticoagulant (DOAC) therapy in patients with cancer. We evaluated the prevalence of potential DOAC/antineoplastic agent DDIs and the one-year cumulative incidence of switching from low-molecular-weight heparin (LMWH) to a DOAC in patients with cancer.Methods: Patients with cancer and an indication of LMWH were included from Herlev and Gentofte Hospital, Denmark, in the 2014-2019 period. Follow-up was initiated when the first dose of LMWH was dispensed. Data were obtained from electronic medical records. One-year cumulative incidence of switching from LMWH to DOAC was estimated using the Aalen-Johansen estimator. Potential DDIs were evaluated using a report from the European Heart Rhythm Association (EHRA) and a review by Hellfritzsch et al. RESULTS. A total of 161 patients were included with a median age of 70.8 (interquartile range: 64.2-76.1) years. The one-year cumulative incidence of switching from LMWH to DOAC was 32% (95% confidence intervals: 21-43%) in patients eligible for DOACs. Using the EHRA report, a total of 24% of antineoplastic agents were not identified. This percentage decreased to 8% using data from Hellfritzsch et al. CONCLUSIONS. In patients with cancer, the one-year cumulative incidence of switching from LMWH to DOAC was less-t 35% in patients eligible for DOAC, revealing a potential for improved anticoagulant treatment. Furthermore, contemporary data elaborated on potential DDIs between DOACs/antineoplastic agents.Funding: \"Helsefonden\" (21-B-0350) and the \"Karen Elise Jensens Fonden\" (29-4-2021) funded the study.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"71 2","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139691375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adherence to guidelines prior to endoscopic sinus surgery in patients with chronic rhinosinusitis and asthma. 慢性鼻窦炎和哮喘患者在接受内窥镜鼻窦手术前遵守指南的情况。

IF 1.6 4区医学

Danish medical journal Pub Date : 2024-01-25 DOI: 10.61409/A04230241

Lotte Buskbjerg Nøhr, Therese Ovesen, Kasra Zainali-Gill

{"title":"Adherence to guidelines prior to endoscopic sinus surgery in patients with chronic rhinosinusitis and asthma.","authors":"Lotte Buskbjerg Nøhr, Therese Ovesen, Kasra Zainali-Gill","doi":"10.61409/A04230241","DOIUrl":"10.61409/A04230241","url":null,"abstract":"Introduction: Optimal care for patients with simultaneous chronic rhinosinusitis (CRS) and asthma is often complicated due to interaction between these conditions. This study depicts the lack of attention to asthma within the otorhinolaryngological field, and the relationship between CRS and asthma, including the risk of revision surgery in such patients.Methods: A retrospective cohort study was conducted on patients undergoing functional endoscopic sinus surgery (FESS) because of CRS with nasal polyps (CRSwNP) and without nasal polyps in a five-year period. Patients were examined for adherence to guidelines, asthma, revision FESS, allergies and septo-/turbinoplasty. Results were compared to international reports.Results: A total of 589 patients had FESS because of CRS of whom 203 (34.5%) had co-existing asthma. A higher risk of asthma (relative risk (RR) = 1.82 (95% confidence interval (CI): 1.29-2.56), p less-than 0.001) and revision FESS (RR = 2.20 (95% CI: 1.33-3.65), p less-than 0.001) was found in patients with CRSwNP. Attention to asthma was poor in patients with no asthma diagnosis before referral.Conclusions: Asthma was lower in the study population than in the literature. Danish national guidelines on CRS management are insufficient regarding attention to asthma. Results call attention to the need for more multidisciplinary team management.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"71 2","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139691373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic flow of patients in a national fast-track referral system for malignant melanoma. 全国恶性黑色素瘤快速转诊系统中患者的诊断流程。

IF 1.6 4区医学

Danish medical journal Pub Date : 2024-01-25 DOI: 10.61409/A07230435

Silje Haukali Omland, Anna Harager, Peter Phillipsen, Katrine Karmisholt

{"title":"Diagnostic flow of patients in a national fast-track referral system for malignant melanoma.","authors":"Silje Haukali Omland, Anna Harager, Peter Phillipsen, Katrine Karmisholt","doi":"10.61409/A07230435","DOIUrl":"10.61409/A07230435","url":null,"abstract":"INTRODUCTION. Timely diagnosis of malignant melanoma (MM) is crucial for optimal patient outcomes. Thus, the Danish Health Authority implemented a fast-track referral system (FTRS) comprising a clinical diagnostic filter function (CDFF) and a cancer package. This study aimed to characterise the flow of patients with a tentative MM diagnosis referred through the CDFF to a department of dermatology.\u0000\u0000METHODS. Retrospective data from the Danish patient and pathology file system were analysed for patients referred to the Department of Dermato-Venereology at Bispebjerg Hospital, Denmark, via the CDFF, with suspected MM in a one-year period.\u0000\u0000RESULTS. Among 860 patients with 895 skin lesions, 283 (31.6%) were discharged with a clinical benign diagnosis after their initial consultation, whereas treatment of another 77 (8.6%) patients concluded following a three-month observation period. One-year follow-up of these 360 (283 + 77) clinically benign skin lesions showed no malignancy. Among 100 MM-suspicious lesions promptly referred for excision to a department of plastic surgery, 48% were MM.\u0000\u0000CONCLUSIONS. In a Danish population with tentative MM diagnosis referred through the CDFF to a dermatological hospital department, one-third of patients were discharged with a clinically benign diagnosis. Half of the skin lesions referred for excision to the department of plastic surgery were MM. This indicates a decreased burden of overdiagnosis and a potential reduction of unnecessary surgical scars when dermatologists serve as gate keepers of the FTRS for MM.\u0000\u0000FUNDING. None\u0000\u0000TRIAL REGISTRATION. Data obtained with permission from BBH j. no. 20078406.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"71 2","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139691374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The therapeutic potential of galanin in the management of pain - a review article. 加拉宁在治疗疼痛方面的潜力--综述文章。

IF 1.6 4区医学

Danish medical journal Pub Date : 2024-01-23 DOI: 10.61409/A10230653

Tomas Hökfelt, Zsuzsanna Wiesenfeld-Hallin

引用次数: 0

Outpatient pain service in trauma and orthopaedic surgery. 创伤和矫形外科疼痛门诊服务。

IF 1.6 4区医学

Danish medical journal Pub Date : 2024-01-23 DOI: 10.61409/A02230105

Claus Bredahl, Simone Høstgaard, Jannie Bisgaard

{"title":"Outpatient pain service in trauma and orthopaedic surgery.","authors":"Claus Bredahl, Simone Høstgaard, Jannie Bisgaard","doi":"10.61409/A02230105","DOIUrl":"10.61409/A02230105","url":null,"abstract":"Introduction: Chronic pain is a common complication after surgery and trauma. The incidence of chronic pain may potentially be reduced by effective management of severe acute pain, in hospital and during the subacute post-operative phase at home.Methods: This was a cohort study from an outpatient follow-up service for patients with pain at discharge after orthopaedic surgery and trauma in a level 1 university hospital setting. The patients' charts were reviewed. Demographics, diagnosis and treatment were registered. The objective of this study was to describe the first five years of experience with this service.Results: A total of 261 patients were included. The median age was 39 (interquartile range (IQR): 26-76) years, and 53% were men. The median pain duration was ten (IQR: 5-22) months. Neuropathic pain was diagnosed in 83% of patients. Complex regional pain syndrome was diagnosed in 10% and suspected in 8%. Before the consultation, 48% were using paracetamol and/or non-steroid anti-inflammatory drugs (NSAIDs), 25% opioids, and 36% used gabapentioids or antidepressants. After their consultation, only 13% used paracetamol and/or NSAIDs and 8% opioids, whereas 86% were treated with gabapentinoids or antidepressants. A plan for opioid weaning was provided for all patients if opioids were continued (8%).Conclusions: Establishing an outpatient pain service for persistent pain after surgery and trauma may encourage the use of analgesia regimens that are in accordance with international guidelines and ensure that opioids are not continued inappropriately.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"71 2","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139691376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correspondence on "cover letters written by ChatGPT-4 or humans". 关于 "由 ChatGPT-4 或人类撰写的求职信 "的通信。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-12-18

Hinpetch Daungsupawong, Viroj Wiwanitkit

引用次数: 0

Biomimetics and planetary health - a review of human diseases in interaction with the environment and ecosystem. 生物仿生学与地球健康--回顾人类疾病与环境和生态系统的相互作用。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-12-18

Peter Stenvinkel

引用次数: 0

Complications in hepatic vein catheterisation and transjugular liver biopsy. 肝静脉导管插入术和经颈静脉肝活检术的并发症。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-12-18

Nanna Hansen, Annette Dam Fialla

{"title":"Complications in hepatic vein catheterisation and transjugular liver biopsy.","authors":"Nanna Hansen, Annette Dam Fialla","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Portal pressure predicts the occurrence of decompensations in cirrhosis. Portal pressure is primarily measured via hepatic vein catheterisation (HVC), to which a transjugular liver biopsy (TJLB) may be added. Indications for HVC are mainly therapy control and prognosis. TJLB is performed when a percutaneous liver biopsy is contraindicated or for other diagnostic reasons. Both procedures have reported low complication rates. The aim of this study was to identify indications and 30-day postprocedural complications.Methods: Based on procedure codes, a list was generated in the report database compromising procedures from 1 January 2018 to 31 January 2022. Procedures were identified in electronic charts (Cosmic Arkiv). A total of 209 patients undergoing 277 procedures were included. Information regarding indications, complications, age, sex, diagnosis, comorbidity and blood tests was also analysed.Results: The more frequently reported indications for HVC were control of betablockers and diagnosis. Indications for TJLB were diagnostic and research purposes. Complications after HVC included pain and transient supraventricular arrythmias. Four major complications after TJLB were found, which led to admission due to various causes of bleeding.Conclusion: HVC and TJLB are safe procedures. The complication rate for HVC and TJLB was 3.3% and 6.8%, respectively. Complications were minor; only four major complications after TJLB were found - none of which were mortal.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"71 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139484842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reply to "Correspondence on 'cover letters written by ChatGPT-4 or humans'". 答复 "关于'由 ChatGPT-4 或人类撰写的求职信'的通信"。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-12-18

Can Deniz Deveci, Jason Joe Baker, Binyamin Sikander, Jacob Rosenberg

引用次数: 0