Danish medical journal最新文献_第9页

Skin lesions in 397 children referred for forensic medical examination on suspicion of physical abuse. 397名儿童因涉嫌身体虐待而被转介进行法医检查，发现皮肤损伤。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-07-06

Lise Frost, Line Qvist Borreschmidt, Dorthe Arenholt Bindslev

{"title":"Skin lesions in 397 children referred for forensic medical examination on suspicion of physical abuse.","authors":"Lise Frost, Line Qvist Borreschmidt, Dorthe Arenholt Bindslev","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Physical child abuse is a well-known global health problem. Considerable efforts have been devoted to identifying predictors of physical abuse.Methods: This study included all 397 cases in the cohort of children aged 0-18 years referred to the Department of Forensic Medicine, Aarhus University, Denmark, between 2000 and 2020 on suspicion of exposure to physical abuse. The number, character and location of skin lesions were described. Bone fractures were recorded. A total of 59 cases involving weapons and sharp force violence related to attack or fighting between young people were assessed as a separate group.Results: The annual number of cases referred increased. The male-to-female ratio in the cohort was 6:4. Bruising was the most common skin manifestation in the blunt force violence (BFV) group; 72.2% of the individuals had skin lesions on the head and neck, thus visible on a normally dressed child. Lesions on the hands and arms were present in 69.8% of the BFV cases and may partially reflect defensive reactions. One or more bone fractures were recorded in 19.5% of the BFV group. Occult fractures were observed in 40% of the children in the BFV group ≤ 2 years of age.Conclusions: More than 70% of the children in the BFV group had lesions on the head and neck visible on a normally dressed child. Skin lesions on hands and arms, which are visible on a lightly dressed child, were just as frequent. Persons with close relation to children should be aware of this opportunity to spot non-accidental skin injuries.Funding: none.Trail registration: not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"70 8","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10442627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ear tubes in children with otitis media reduce parental sick leave from work and socioeconomic costs. 中耳炎儿童的耳管减少了父母的病假和社会经济成本。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-07-03

Louise Jürgens, Michael Lyscher, Thomas Qvist Barrett, Peter Koefoed Tingsgaard, Lene Dahl Siggard

{"title":"Ear tubes in children with otitis media reduce parental sick leave from work and socioeconomic costs.","authors":"Louise Jürgens, Michael Lyscher, Thomas Qvist Barrett, Peter Koefoed Tingsgaard, Lene Dahl Siggard","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: This study aimed to investigate changes in parental sick leave after tympanostomy tube (TT) insertion in children with otitis media (OM) and to estimate the overall cost reduction in case of decreased caregiver sick leave from work during a 12-month period after TT insertion.Methods: A total of 4,708 children less-than 12 years from the database of the Danish ENT Specialists Organisation were included. Questionnaires were sent two days prior to TT insertion and subsequently 1, 3, 6, 9, 12, 15, 18, 21 and 24 months after TT insertion. The questions included symptom duration, patient satisfaction and symptom relief. Furthermore, parental sick leave occurrence was registered before and after TT insertion. The overall cost reduction estimate was based on comparison of the direct and indirect costs of two treatment regimes. Treatment A was non-surgical and antibiotics only. Treatment B comprised TT insertion and antibiotics as needed.Results: The main results were that the risk of parental sick leave decreased significantly (p less-than 0.005) one month after TT insertion compared with baseline; odds ratio = 0.21 (95% confidence interval: 0.19-0.24). The decrease remained stable during the entire follow-up period. The estimate of the total cost reduction between Treatment A (non-TT insertion) and Treatment B (TT insertion) was 3,118.34 DKK/child/year.Conclusion: TT insertion is associated with a significant decrease in parental sick leave and may possibly contribute to substantial socioeconomic savings.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"70 8","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10069832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical implications of multidisciplinary team pancreatic cyst evaluation. 多学科小组胰腺囊肿评估的临床意义。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-06-27

Marie Ingemann Pedersen, Lars Peter Skovgaard Larsen, Jakob Kirkegård, Jacob Nygaard, Peter Kissmeyer, Frank Viborg Mortensen, Anders R Knudsen

{"title":"Clinical implications of multidisciplinary team pancreatic cyst evaluation.","authors":"Marie Ingemann Pedersen, Lars Peter Skovgaard Larsen, Jakob Kirkegård, Jacob Nygaard, Peter Kissmeyer, Frank Viborg Mortensen, Anders R Knudsen","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: The detection of incidental pancreatic cysts (PCs) is increasing due to frequent use of imaging. The aim of the present study was to evaluate the clinical consequences of regular multidisciplinary team (MDT) conferences for patients with PCs.Methods: All patient data were obtained by review of patient medical records. PCs were assessed at the weekly MDT in accordance with the revised Fukuoka guidelines.Results: A total of 455 patients were evaluated within 12 months. A large proportion of the cysts could not be characterised and was handled as branch duct (BD)-intraductal papillary mucinous neoplasia (IPMN). A total of 245 patients were included in a follow-up programme, whereas 175 patients were excluded. Further diagnostic work-up was recommended for 31 patients. A total of 66 patients were reviewed on MDT a second time during the study period, eight of whom received a diagnosis different from that given at the first MDT. A total of 35 patients with mucinous PC or cysts treated as BD-IPMN had either worrisome features (WF) or high-risk stigmata (HRS), four of these patients had a PC ≤ 10 mm. Indication for surgery was WF or HRS and, in the course of 12 months, six patients were recommended surgery taking their PS into account. Two patients had a malignant and two had a premalignant lesion.Conclusion: In all, 455 patients were evaluated to find 35 patients with suspected premalignant PCs. This means that almost 8% of the referred patients had suspicious lesions, which indicates a need for a regular MDT conference.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"70 7","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9751701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lipids and lipoproteins. 脂质和脂蛋白。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-06-26

Anders Berg Wulff, Børge G Nordestgaard

引用次数: 0

Availability of social authorities in a simulated paediatric emergency. 社会当局在模拟儿科紧急情况中的可用性。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-06-23

Katrine Bennett Gyldenkærne, Dan Isbye, Lars S Rasmussen

{"title":"Availability of social authorities in a simulated paediatric emergency.","authors":"Katrine Bennett Gyldenkærne, Dan Isbye, Lars S Rasmussen","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: In cases of parental opposition to emergency medical care for minors, defined as children below 15 years of age, involving the social authorities may be necessary. When medical personnel assess that an intervention is in the minor's best interests, approval for such intervention is warranted from the local authorities in the municipality of residence. It was the primary aim of this study to assess the urgent availability of these authorities.Methods: The urgent phone availability of social authorities at the 98 Danish local municipal offices was assessed during both regular hours and off-hours. The primary objective was to assess availability during regular hours. Urgent availability was predefined as obtained contact to a self-proclaimed accountable authority within 30 minutes. Secondary objectives were assessment of off-hour availability, time until obtained contact and number of contact links.Results: Contact was obtained within 30 minutes in 59 inquiries (~ 58%) made during regular hours, with a median of three contact links and a median time until contact of eight minutes (interquartile range (IQR): 5.5-11 minutes). During off-hours, contact was obtained within 30 minutes in 91 inquiries (~ 93%), with a median of two contact links and a median time until contact of seven minutes (IQR: 5-12 minutes).Conclusion: During regular hours, we found that an accountable authority was urgently available for attendance to a case of parental opposition to emergency medical care of a minor within 30 minutes at the local municipal office in 58% of Danish municipalities.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"70 7","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10055018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevention and management of obesity in a lifetime perspective. 从终生角度预防和管理肥胖。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-06-20

Mads F Hjorth, Alexandra S Helbo, Arne Astrup

引用次数: 0

Co-regulation of learning in a department of paediatrics. 儿科学习的共同管理。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-06-15

Nanna Søndermølle Svensson, Thomas Balslev

{"title":"Co-regulation of learning in a department of paediatrics.","authors":"Nanna Søndermølle Svensson, Thomas Balslev","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Co-regulated learning (CRL) is a process in which the learner's regulation of learning is guided by social transactions. The change in learning techniques during the transition from university to workplace learning and the rapidly changing learning environment make awareness of CRL extremely relevant. This study examined CRL among medical students and residents and identified the factors affecting CRL.Methods: We applied an explorative approach using direct observation and semi-structured focus group discussions (FGD). The first author made direct observations that produced explorative data about actual behaviour. However, this was not sufficiently sensitive to capture the participants' full perceptions of CRL. Therefore, we conducted semi-structured FGD that involved interactions and reflections among the participants.Results: This study suggests that CRL occurred in multiple situations and was affected by many factors. The stimulating factors identified were a supportive learning environment, feedback based on observations and questioning by a supervisor, dyad work and interactive, bimodal presentation of emergency cases at the morning conference. Time pressure, heavy workload and shortage of specialists were inhibiting factors.Conclusion: We identified several factors affecting CRL. A focus on the augmentation of stimulating factors and reduction of inhibiting factors may help medical students and residents develop CRL.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"70 7","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10055014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PET/CT compared with temporal artery biopsy for giant cell arteritis. 巨细胞动脉炎的PET/CT与颞动脉活检的比较。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-06-14

Søren Lambæk, Marianne Pedersen, Therese Ovesen

{"title":"PET/CT compared with temporal artery biopsy for giant cell arteritis.","authors":"Søren Lambæk, Marianne Pedersen, Therese Ovesen","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: This study aims to evaluate the use of PET/CT compared with temporal artery biopsy (TAB) as a diagnostic tool in patients suspected of giant cell arteritis (GCA) and to determine the influence of glucocorticoid treatment on diagnostic performance.Methods: This was a retrospective cohort study; 191 patients booked for TAB during a five-year period were screened for inclusion. The study population was divided into two groups. A TAB group containing patients who completed only TAB to assess potential selection bias and a PET/CT + TAB group containing patients with TAB and PET/CT to evaluate the diagnostic performance. The clinical diagnosis of GCA was established after a follow-up period of minimum six months.Results: A total of 157 patients were included in the study: 77 patients in the TAB group and 80 patients in the PET/CT + TAB group. The result of TAB and PET/CT did not match in 15 cases. Overall, the negative agreement rate of TAB and PET/CT was 19% (95% confidence interval (CI): 11-29%). The sensitivity of PET/CT was 76% (95% CI: 63-90%) compared with the clinical diagnosis. The sensitivity of TAB was lower: 63% (95% CI: 48-78%), but not significantly different (z = 1.26/p = 0.2). The sensitivity of both PET/CT and TAB increased to 85% (95% CI: 72-99%) and 74% (95% CI: 58-91%) if performed within three days of glucocorticoid therapy.Conclusion: This study strengthens the evidence that conventional PET/CT is a useful imaging modality in the diagnosis of the entire spectrum of GCA, including the assessment of both cranial and extra-cranial arteries.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"70 7","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10055012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vitamin B12 reference intervals. 维生素B12参考区间。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-05-23

Stine Linding Andersen, Annebirthe Bo Hansen, Peter Hindersson, Lærke Andersen, Peter Astrup Christensen

{"title":"Vitamin B12 reference intervals.","authors":"Stine Linding Andersen, Annebirthe Bo Hansen, Peter Hindersson, Lærke Andersen, Peter Astrup Christensen","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: P-Vitamin B12 is a commonly used biochemical test. Evaluation of test results and diagnosis of vitamin B12 deficiency are challenging, and the role of different biochemical methods remains unclear.Methods: The aim of this study was to establish reference intervals for plasma vitamin B12 concentration using different immunoassays (method 1: Alinity, Abbott Laboratories; method 2: Cobas 6000, Roche Diagnostics; method 3: Atellica IM, Siemens Healthineers). Direct reference intervals were established among blood donors (n = 129) and indirect reference intervals among adult patient results of plasma vitamin B12 concentration requested by general practitioners in the North Denmark Region from 15 August to 15 October 2022 (n = 34,181). Finally, the frequency of low vitamin B12 concentration using different uniform cut-offs was evaluated.Results: Direct reference intervals (2.5-97.5 percentiles) were as follows for method 1: 168-553 pmol/l; method 2: 202-641 pmol/l; and method 3: 211-551 pmol/l. Indirect reference intervals were as follows for method 1: 133-541 pmol/l; method 2: 172-619 pmol/l; and method 3: 182-162-206 pmol/l. When different cut-offs were applied to patient results, the frequency of having a vitamin B12 concentration below 250 pmol/l differed by biochemical method: 33% (method 1), 17% (method 2) and 14% (method 3).Conclusion: Measurement of plasma vitamin B12 concentration using different immunoassays revealed results and reference intervals that were not interchangeable. Clinical guidelines for the diagnosis of vitamin B12 deficiency should consider the biochemical methods used.Funding: None.Trial registration: None.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"70 6","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9665100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tonsillectomy and risk of post-tonsillectomy haemorrhage - a protocol for a randomised clinical trial. 扁桃体切除术和扁桃体切除术后出血的风险-一项随机临床试验的方案。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-05-23

Michael F Howitz, Frej Juul Vilhelmsen, Kasper Wennervaldt, Valdemar Trolle, Malene Kirchmann

{"title":"Tonsillectomy and risk of post-tonsillectomy haemorrhage - a protocol for a randomised clinical trial.","authors":"Michael F Howitz, Frej Juul Vilhelmsen, Kasper Wennervaldt, Valdemar Trolle, Malene Kirchmann","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Tonsillectomy is one of the most common procedures in the ear, nose and throat field, and 7.7% of the Danish population had undergone a tonsillectomy by the age 20 years in 2012. One feared complication is post-tonsillectomy haemorrhage (PTH), which in a Danish register-based study was found to increase from 3% in 1991 to 13% in 2012. PTH represents a significant risk and deaths are reported in the literature. The aim of the trial is to compare hot and cold haemostasis during tonsillectomy and assess, firstly, the risk of PTH and, secondly, the reported pain perception.Methods: This is a single-centre, two-arm, interventional randomised controlled trial. The study targets patients > 12 years of age referred for tonsillectomy. Participants will have both tonsils removed; on one side cold haemostasis will be performed and on the other hot diathermia will secure haemostasis. The participants will subsequently receive three questionnaires in the course of a month concerning bleeding episodes and pain perception. Owing to the study design, patients and surgeons act as their own controls.Conclusions: The results of the study may guide future research and practice of tonsillectomy to reduce the risk of PTH.Funding: Lizzi and Mogens Staal Fonden and Nordsjællands Hospital. The funding sources had no influence on trial design, data collection, analysis or publication.Trial registration: Clinicaltrials: gov Identifier: NCT05161754. Registration date: 20042021; version 2: 20042021.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"70 6","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10010030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0