Danish medical journal最新文献_第8页

Diagnostic flow of patients in a national fast-track referral system for malignant melanoma. 全国恶性黑色素瘤快速转诊系统中患者的诊断流程。

IF 1.6 4区医学

Danish medical journal Pub Date : 2024-01-25 DOI: 10.61409/A07230435

Silje Haukali Omland, Anna Harager, Peter Phillipsen, Katrine Karmisholt

{"title":"Diagnostic flow of patients in a national fast-track referral system for malignant melanoma.","authors":"Silje Haukali Omland, Anna Harager, Peter Phillipsen, Katrine Karmisholt","doi":"10.61409/A07230435","DOIUrl":"10.61409/A07230435","url":null,"abstract":"INTRODUCTION. Timely diagnosis of malignant melanoma (MM) is crucial for optimal patient outcomes. Thus, the Danish Health Authority implemented a fast-track referral system (FTRS) comprising a clinical diagnostic filter function (CDFF) and a cancer package. This study aimed to characterise the flow of patients with a tentative MM diagnosis referred through the CDFF to a department of dermatology.\u0000\u0000METHODS. Retrospective data from the Danish patient and pathology file system were analysed for patients referred to the Department of Dermato-Venereology at Bispebjerg Hospital, Denmark, via the CDFF, with suspected MM in a one-year period.\u0000\u0000RESULTS. Among 860 patients with 895 skin lesions, 283 (31.6%) were discharged with a clinical benign diagnosis after their initial consultation, whereas treatment of another 77 (8.6%) patients concluded following a three-month observation period. One-year follow-up of these 360 (283 + 77) clinically benign skin lesions showed no malignancy. Among 100 MM-suspicious lesions promptly referred for excision to a department of plastic surgery, 48% were MM.\u0000\u0000CONCLUSIONS. In a Danish population with tentative MM diagnosis referred through the CDFF to a dermatological hospital department, one-third of patients were discharged with a clinically benign diagnosis. Half of the skin lesions referred for excision to the department of plastic surgery were MM. This indicates a decreased burden of overdiagnosis and a potential reduction of unnecessary surgical scars when dermatologists serve as gate keepers of the FTRS for MM.\u0000\u0000FUNDING. None\u0000\u0000TRIAL REGISTRATION. Data obtained with permission from BBH j. no. 20078406.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"71 2","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139691374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The therapeutic potential of galanin in the management of pain - a review article. 加拉宁在治疗疼痛方面的潜力--综述文章。

IF 1.6 4区医学

Danish medical journal Pub Date : 2024-01-23 DOI: 10.61409/A10230653

Tomas Hökfelt, Zsuzsanna Wiesenfeld-Hallin

引用次数: 0

Outpatient pain service in trauma and orthopaedic surgery. 创伤和矫形外科疼痛门诊服务。

IF 1.6 4区医学

Danish medical journal Pub Date : 2024-01-23 DOI: 10.61409/A02230105

Claus Bredahl, Simone Høstgaard, Jannie Bisgaard

{"title":"Outpatient pain service in trauma and orthopaedic surgery.","authors":"Claus Bredahl, Simone Høstgaard, Jannie Bisgaard","doi":"10.61409/A02230105","DOIUrl":"10.61409/A02230105","url":null,"abstract":"Introduction: Chronic pain is a common complication after surgery and trauma. The incidence of chronic pain may potentially be reduced by effective management of severe acute pain, in hospital and during the subacute post-operative phase at home.Methods: This was a cohort study from an outpatient follow-up service for patients with pain at discharge after orthopaedic surgery and trauma in a level 1 university hospital setting. The patients' charts were reviewed. Demographics, diagnosis and treatment were registered. The objective of this study was to describe the first five years of experience with this service.Results: A total of 261 patients were included. The median age was 39 (interquartile range (IQR): 26-76) years, and 53% were men. The median pain duration was ten (IQR: 5-22) months. Neuropathic pain was diagnosed in 83% of patients. Complex regional pain syndrome was diagnosed in 10% and suspected in 8%. Before the consultation, 48% were using paracetamol and/or non-steroid anti-inflammatory drugs (NSAIDs), 25% opioids, and 36% used gabapentioids or antidepressants. After their consultation, only 13% used paracetamol and/or NSAIDs and 8% opioids, whereas 86% were treated with gabapentinoids or antidepressants. A plan for opioid weaning was provided for all patients if opioids were continued (8%).Conclusions: Establishing an outpatient pain service for persistent pain after surgery and trauma may encourage the use of analgesia regimens that are in accordance with international guidelines and ensure that opioids are not continued inappropriately.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"71 2","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139691376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correspondence on "cover letters written by ChatGPT-4 or humans". 关于 "由 ChatGPT-4 或人类撰写的求职信 "的通信。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-12-18

Hinpetch Daungsupawong, Viroj Wiwanitkit

引用次数: 0

Biomimetics and planetary health - a review of human diseases in interaction with the environment and ecosystem. 生物仿生学与地球健康--回顾人类疾病与环境和生态系统的相互作用。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-12-18

Peter Stenvinkel

引用次数: 0

Complications in hepatic vein catheterisation and transjugular liver biopsy. 肝静脉导管插入术和经颈静脉肝活检术的并发症。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-12-18

Nanna Hansen, Annette Dam Fialla

{"title":"Complications in hepatic vein catheterisation and transjugular liver biopsy.","authors":"Nanna Hansen, Annette Dam Fialla","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Portal pressure predicts the occurrence of decompensations in cirrhosis. Portal pressure is primarily measured via hepatic vein catheterisation (HVC), to which a transjugular liver biopsy (TJLB) may be added. Indications for HVC are mainly therapy control and prognosis. TJLB is performed when a percutaneous liver biopsy is contraindicated or for other diagnostic reasons. Both procedures have reported low complication rates. The aim of this study was to identify indications and 30-day postprocedural complications.Methods: Based on procedure codes, a list was generated in the report database compromising procedures from 1 January 2018 to 31 January 2022. Procedures were identified in electronic charts (Cosmic Arkiv). A total of 209 patients undergoing 277 procedures were included. Information regarding indications, complications, age, sex, diagnosis, comorbidity and blood tests was also analysed.Results: The more frequently reported indications for HVC were control of betablockers and diagnosis. Indications for TJLB were diagnostic and research purposes. Complications after HVC included pain and transient supraventricular arrythmias. Four major complications after TJLB were found, which led to admission due to various causes of bleeding.Conclusion: HVC and TJLB are safe procedures. The complication rate for HVC and TJLB was 3.3% and 6.8%, respectively. Complications were minor; only four major complications after TJLB were found - none of which were mortal.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"71 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139484842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reply to "Correspondence on 'cover letters written by ChatGPT-4 or humans'". 答复 "关于'由 ChatGPT-4 或人类撰写的求职信'的通信"。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-12-18

Can Deniz Deveci, Jason Joe Baker, Binyamin Sikander, Jacob Rosenberg

引用次数: 0

Intramedullary nailing versus external ring fixator for treatment of tibial fractures - a study protocol for a randomised clinical trial. 髓内钉与环形外固定器治疗胫骨骨折--随机临床试验的研究方案。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-12-06

Rasmus Stokholm, Peter Larsen, Jan Duedal Rölfing, Juozas Petruskevicius, Morten K Rasmussen, Steffen Skov, Rasmus Elsoe

{"title":"Intramedullary nailing versus external ring fixator for treatment of tibial fractures - a study protocol for a randomised clinical trial.","authors":"Rasmus Stokholm, Peter Larsen, Jan Duedal Rölfing, Juozas Petruskevicius, Morten K Rasmussen, Steffen Skov, Rasmus Elsoe","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Tibial shaft fractures are among the most common lower extremity fractures. Treatment of tibial shaft fractures with intramedullary nailing has become the treatment of choice in adults. However, commonly reported outcomes include knee pain, limitations in activities of daily living and reduction in quality of life (QOL). The literature lacks high-quality studies to document superiority of intramedullary nailing versus other surgical treatment methods. The present study aims to compare the 12-month Knee Injury and Osteoarthritis Outcome Score (KOOS) - sport and recreation activities (sport/rec) after standard intramedullary nailing with external ring fixation for adult patients with isolated tibial shaft fractures.Methods: This study is a multicentre randomised, prospective clinical trial. A total of 67 patients will be included in the study, and the primary outcome will be the KOOS-sport/rec at 12 months after surgery.Conclusions: With KOOS-sport/rec as the primary outcome, the findings of the present study are expected to advance our understanding of knee pain, function and QOL, regardless of the treatment option and the outcome of the study.Funding: The project is partially funded by the Independent Research Found Denmark.Trial registration: Clinicaltrials: gov ID: NCT-03945669, version 1.1, 21 September 2022.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"71 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139484931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Randomised controlled trial of in- versus out-patient management of benign hemithyroidectomy. 良性血肿切除术住院与门诊管理的随机对照试验。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-12-06

Carl Frederik Haugaard, Preben Homøe, Alexander Nygren, Ole Mathiesen, Lise Nørrekjær Hansen, Gitte Bjørn Hvilsom

{"title":"Randomised controlled trial of in- versus out-patient management of benign hemithyroidectomy.","authors":"Carl Frederik Haugaard, Preben Homøe, Alexander Nygren, Ole Mathiesen, Lise Nørrekjær Hansen, Gitte Bjørn Hvilsom","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Outpatient (OPT) thyroid surgery is increasing, with patient selection being pivotal for safety. While numerous studies exist, most are retrospective and encompass both benign and malignant cases.Methods: We conducted a randomised clinical trial on patients undergoing hemithyroidectomy for benign thyroid disease. Participants were assigned to OPT or inpatient groups. We collected data on complications, failure to discharge on surgery day, post-operative pain, nausea, sleep quality and patient satisfaction.Results: Among 97 patients, 27.5% (14/51) in the OPT group could not be discharged on the day of surgery due to minor complications, primarily nausea (36%) and neck swelling (29%). No reoperations were needed. Though OPT patients exhibited a higher rate of minor complications (29%), they reported less post-operative nausea, better sleep and a faster return to normal activity.Conclusions: Discharge on the day of surgery is not always possible with OPT thyroid surgery. However, our findings suggest that OPT hemithyroidectomy for benign cases can be both safe and feasible for a selected group of patients.Funding: None TRIAL REGISTRATION.Clinicaltrials: gov Identifier: NCT02891252.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"71 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139484944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cold steel versus impedance-dependent tissue sealer tonsillectomy - a study protocol for a randomised controlled trial. 冷钢与阻抗依赖组织密封扁桃体切除术-一项随机对照试验的研究方案。

IF 1.6 4区医学

Danish medical journal Pub Date : 2023-11-23

Line Schiøtt Nissen, Jannik Bertelsen, Nina Munk Lyhne, Susanne Holm Nielsen, Pernille Hahn, Jesper Holm, Therese Ovesen

{"title":"Cold steel versus impedance-dependent tissue sealer tonsillectomy - a study protocol for a randomised controlled trial.","authors":"Line Schiøtt Nissen, Jannik Bertelsen, Nina Munk Lyhne, Susanne Holm Nielsen, Pernille Hahn, Jesper Holm, Therese Ovesen","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Approximately 7,000 tonsillectomies are performed annually in Denmark on a benign basis. The cold steel surgical technique is the gold standard. The risk of post tonsillectomy bleeding (PTH) in a centre in Jutland is 7.9%. A new impedance-dependent tissue sealer (IDTS) device has been developed, with preliminary results showing a reduction in operation time, perioperative bleeding and post-operative risk of bleeding of 4.5%.Methods: A randomised, controlled, double-blinded multicentre trial of cold steel tonsillectomy versus IDTS will be performed on 1,250 patients. The main endpoint is PTH, perioperative bleeding, operation time and post-operative pain. The secondary outcomes are days until return to work, food intake, activity and quality of life. Included in the study are patients with indication for surgery weighing ≥ 16 kg, and excluded are patients with malignancy, bleeding disorders and unwillingness to participate in the study.Conclusions: To our knowledge, the present study is the largest randomised controlled trial in ENT surgery in the Nordic countries. The study will potentially provide evidence on PTH regarding two tonsillectomy methods.Funding: The authors have no potential conflicts of interest to declare. The study is supplied with instruments from Medtronic needed for the surgical procedures. Furthermore, a minor part of the funding of the entire project is provided by the aforementioned company. The funding providers have no role in design or conduct of the study.Trial registration: Clinicaltrials: gov with the identification number NCT05270109.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"70 12","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138451173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0