Current Urology Reports最新文献

{"title":"Rethinking Gleason 6 Prostate Cancer: Embracing PrNLMP for Precision and Progress.","authors":"Evan Kovac, Robert E Weiss, Wadih Arap","doi":"10.1007/s11934-025-01285-1","DOIUrl":"10.1007/s11934-025-01285-1","url":null,"abstract":"","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"57"},"PeriodicalIF":2.5,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12256353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Applications and Limitations of Augmented Reality in Urological Surgery: A Practical Primer and 'State of the Field'.","authors":"Vivian L Wang, Lucille G Cheng, Toby S Zhu, Shyam Patnaik, Tatum Tarin","doi":"10.1007/s11934-025-01283-3","DOIUrl":"https://doi.org/10.1007/s11934-025-01283-3","url":null,"abstract":"<p><strong>Purpose of review: </strong>To provide a primer for how augmented reality (AR)-guided surgical technology works at a fundamental level and discuss recent advances and limitations in a rapidly advancing field, including studies aiming to reduce current issues limiting wider adoption.</p><p><strong>Recent findings: </strong>Among the studies published within the last five years, AR-guided technologies have advanced from pre-operative planning to intraoperative use in procedures including robot-assisted radical prostatectomy, percutaneous nephrolithotomy, and renal transplantation. Artificial intelligence (AI) and deep learning techniques have allowed for development of automatic registration to address challenges with soft tissue deformation. Subspecialities which may benefit from further AR/MR adoption include reconstructive and andrology, which were underrepresented in our review. Augmented reality refers to the process of superimposing digital information (e.g., preoperative imaging) on top of the physical world. Along with its interactive counterpart, mixed reality (MR), AR has become an area of sustained research interest in the urological surgery space. This technology has significant implications for surgical accuracy, efficiency, and medical education. As a result, it is critical for clinicians to both be aware of advancements in the field and understand the basics of this technology. We discuss articles published from March 2021 to February 2025, across a range of urologic procedures and applications, and discuss how recent trends point to a shift towards higher-powered, prospective studies incorporating intraoperative usage of AR/MR.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"56"},"PeriodicalIF":2.5,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascular and Anatomical Challenges in Renal Transplant Surgery; What a Urologist Needs to know.","authors":"Isela N Oceguera, Omar Thaher, Dirk Bausch, Sjaak Pouwels","doi":"10.1007/s11934-025-01281-5","DOIUrl":"https://doi.org/10.1007/s11934-025-01281-5","url":null,"abstract":"<p><strong>Purpose of review: </strong>Every surgical procedure presents challenges for surgeons before, during, and after the operation. This review aims to explore strategies for anticipating and addressing these challenges in kidney transplant surgeries.</p><p><strong>Recent findings: </strong>Specifically, it focuses on equipping surgeons with the knowledge necessary to navigate vascular anatomical variations encountered during kidney retrieval and transplantation. By elucidating both typical and uncommon anatomical configurations, surgeons can better anticipate challenges and optimize surgical outcomes. The review underscores the critical importance of understanding kidney vascular anatomical variations in the context of transplantation. By providing insights into preoperative planning and mitigating intraoperative challenges, this knowledge has the potential to significantly improve outcomes for patients undergoing kidney transplantation.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"55"},"PeriodicalIF":2.5,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Outcomes in Urological Surgery for the Elderly: Strategies for Optimization and Risk Reduction.","authors":"Patrick Juliebø-Jones, Christian Beisland","doi":"10.1007/s11934-025-01284-2","DOIUrl":"10.1007/s11934-025-01284-2","url":null,"abstract":"<p><strong>Purpose of review: </strong>The purpose was to present latest findings on factors that can help improve risk profiling for surgery in the elderly and thus improve outcomes.</p><p><strong>Recent findings: </strong>Approximately two thirds of patients undergoing urological surgery are elderly. A number of assessment tools are now available for clinical application to facilitate risk planning when considering surgery. There is an overall lack of trials performed in the elderly on account of a number of factors including cognitive impairment, mobility and perceived lack of benefit. Clinicians are generally poor at estimating 10-year survival in patients and usually underestimate it. Treatment success in this demographic varies from the index patient and an individualised approach should be taken. It is of increasing relevance for clinicians to familiarize themselves with tools that can facilitate surgical care in the elderly. Prospective studies are needed, which also monitor outcomes in patients who did not undergo surgery.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"54"},"PeriodicalIF":2.5,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12209000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Robot-Assisted Versus Open Partial Nephrectomy for Treating Renal Malignancies With An Emphasis on Oncological Outcomes: A Systematic Review and Meta-Analysis of The Literature.","authors":"Diomidis Kozyrakis, Chara Tzavara, Christos Damaskos, Anastasios Zarkadas, Dimitrios Bozios, Athanasios Karmogiannis, Vasileios Konstantinopoulos, Georgios Haronis, Anna-Maria Konomi, Georgios Kallinikas, Konstantinos Safioleas, Athanasios Filios, Despoina Mytiliniou, Evangelos Rodinos, Panagiotis Filios, Dimitrios Dimitroulis","doi":"10.1007/s11934-025-01282-4","DOIUrl":"10.1007/s11934-025-01282-4","url":null,"abstract":"<p><strong>Purpose of review: </strong>Robotic assisted partial nephrectomy (RaPN) is the treatment of choice for small and resectable renal tumors offering better results in terms of blood loss, postoperative complications and length of hospital stay compared with the open partial nephrectomy (OPN), while for both techniques the risk of postoperative renal dysfunction is limited. However, the oncologic outcomes of the robotic procedure are yet to be determined. Therefore, a comprehensive research of PubMed/Medline, Embase and Scopus databases from the year 2000 till June 2024 was performed to elucidate the results related to oncologic outcomes. The ROBINS-I tool for non-randomized cohort studies was applied for the assessment of the quality of the included studies. All statistical analyses were performed with the use of STATA software version 15.0.</p><p><strong>Recent findings: </strong>The study was registered in International Platform of Registered Systematic Review and Metaanalysis Protocols database with the registration number INPLASY202450054. Overall 11 studies with 4758 patients were included in the present systematic review and meta-analysis. No statistically significant difference between the two treatment methods was reconded for the outcomes of overall survival [HR: 1.23 (95% CI: 0.68, 2.20)- p = 0.488], disease-specific survival [OR: 2.53 (95% CI: 0.65, 9.78)- p = 0.179], progression-free survival [HR: 1.04 (95% CI: 0.60, 1.79)- p = 0.901], recurrence-free survival [HR: 0.83 (95% CI = 0.54, 1.27)-p = 0.394] and disease-free survival [OR: 1.01 (95% CI = 0.98, 1.03)-p = 0.582]. The quality of most of the included studies was deemed moderate. Despite the need for more high quality comparative studies it is assumed that these results could be helpful in decision making and in counselling patients with resectable renal tumors to whom a nephron sparing surgery may be considered.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"53"},"PeriodicalIF":2.5,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Off-Label but On-Target: Sacral Neuromodulation for Neurogenic Bladder Dysfunction.","authors":"Keianna Vogel, Nissrine Nakib","doi":"10.1007/s11934-025-01280-6","DOIUrl":"10.1007/s11934-025-01280-6","url":null,"abstract":"<p><strong>Purpose of review: </strong>Neurogenic bladder dysfunction (NBD) is a frequent complication of neurological diseases including Parkinson's disease, multiple sclerosis, spinal cord injury, and spina bifida. Managing NBD remains challenging, especially for patients who fail to respond to standard therapies. Sacral neuromodulation (SNM), though FDA-approved for non-neurogenic conditions, is increasingly explored off-label in neurogenic populations.</p><p><strong>Recent findings: </strong>Recent studies demonstrate that SNM can improve lower urinary tract symptoms, bladder storage, and emptying in select NBD patients. Small case series and retrospective reviews suggest reduced catheterization and medication use. Technological advances, such as closed-loop systems and MRI-compatible devices, are broadening SNM's clinical potential. SNM is emerging as a valuable, minimally invasive treatment for neurogenic bladder dysfunction. Careful patient selection and understanding of underlying pathophysiology are essential for success. As evidence grows and device innovations continue, SNM could reshape management strategies for patients with neurogenic bladder.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"52"},"PeriodicalIF":2.5,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12185588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Packing the Punch: Current and Emerging Treatment Strategies in Metastatic Castration-Sensitive Prostate Cancer.","authors":"Steven P Troy, Christopher D Jakubowski, Benjamin A Gartrell","doi":"10.1007/s11934-025-01272-6","DOIUrl":"10.1007/s11934-025-01272-6","url":null,"abstract":"","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"50"},"PeriodicalIF":2.5,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12182509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144339928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re-appraisal of Standard of Care Imaging to Identify Predictors of Treatment Outcomes among Patients with Bladder and Upper Tract Urothelial Cancers.","authors":"Shelby Harper, Erick M Remer, Nima Almassi","doi":"10.1007/s11934-025-01278-0","DOIUrl":"10.1007/s11934-025-01278-0","url":null,"abstract":"<p><strong>Purpose of review: </strong>Urothelial carcinoma is a prevalent malignancy within the United States that may involve the upper and/or lower urinary tracts. Multimodal treatment is often employed, with transurethral resection and intravesical therapy standard of care for non-muscle-invasive disease; neoadjuvant systemic therapy followed by radical cystectomy or trimodal therapy for muscle-invasive disease; and combination immune checkpoint inhibitors and antibody-drug conjugates standard of care for metastatic disease. These treatments carry risks of surgical complication or treatment-associated toxicity which can impair quality of life. Predictive biomarkers of treatment tolerability are currently limited.</p><p><strong>Recent findings: </strong>There is emerging evidence that radiological biomarkers can predict treatment outcomes among patients with urothelial carcinoma. In this review, we evaluate the existing data on radiological biomarkers evaluable from current standard-of-care imaging in predicting treatment outcome among patients with urothelial carcinoma.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"51"},"PeriodicalIF":2.5,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12182448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144339929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benign Prostatic Hyperplasia and Sexual Dysfunction: Review of the Impact of New Medical and Surgical Therapies on Sexual Health.","authors":"Danish Singh, Tivoli Nguyen, Patrick Burnam, Jacob Greenberg, Omer Raheem, Wayne Hellstrom","doi":"10.1007/s11934-025-01279-z","DOIUrl":"10.1007/s11934-025-01279-z","url":null,"abstract":"<p><strong>Purpose of review: </strong>The aim of this review is to evaluate recent literature surrounding the impact of new medical and surgical therapies for benign prostatic hyperplasia (BPH) on sexual health and function.</p><p><strong>Recent findings: </strong>Recent randomized controlled trials evaluating patients treated with Optilume, Rezum, Urolift, iTind, and prostatic artery embolism reported minimal associated risks for the development of sexual dysfunction. However, these treatments provide inferior improvement in lower urinary tract symptoms (LUTS) when compared to transurethral resection of the prostate (TURP) and simple prostatectomy. Aquablation demonstrates similar improvement in LUTS while significantly minimizing ejaculatory dysfunction compared to TURP. Management of BPH must include patient counseling on the potential risks of sexual dysfunction associated with both medical and surgical therapies. Future research should be guided towards comparing minimally invasive surgical therapies to one another and collecting long-term data on the durability of these therapies on urinary and sexual function.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"49"},"PeriodicalIF":2.5,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Important Concepts in Building a Positive Culture in a Residency Program.","authors":"Robert Fisch, Manish Kuchakulla, Michael Tzeng, Aaron A Gurayah, Runzhuo Ma, Robert Pearce, Richard Lee, Meenakshi Davuluri","doi":"10.1007/s11934-025-01273-5","DOIUrl":"https://doi.org/10.1007/s11934-025-01273-5","url":null,"abstract":"<p><strong>Purpose of review: </strong>Despite recent increased focus on urology resident wellbeing, rates of burnout remain high. Addressing this requires a multifaceted approach. This review examines recent literature to identify key strategies for fostering a positive urology residency culture to optimize training and minimize burnout.</p><p><strong>Recent findings: </strong>We identified 5 key strategies for fostering a positive residency culture: wellness, safety, mentorship, education, and traditions. Proactive wellness initiatives involve providing access to health resources as well as social programming. Ensuring resident safety requires minimizing physical and psychological mistreatment while ensuring access to basic needs. Formal mentorship strengthens professional growth and personal fulfilment. Advancing resident education through structured learning models and access to key resources improves wellbeing. Institutional traditions build camaraderie, unity, and a shared sense of purpose. Creating a strong urology residency culture requires a multidimensional approach. Integrating these elements can improve resident satisfaction, reduce burnout, and strengthen both resident professional growth and patient care.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"48"},"PeriodicalIF":2.5,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}