{"title":"Difficult Access in Endourology: Anatomical Challenges and Contemporary Management.","authors":"Vivek Paharwar, Abhishek Singh, Shreyans Jain","doi":"10.1007/s11934-026-01357-w","DOIUrl":"https://doi.org/10.1007/s11934-026-01357-w","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review provides a comprehensive overview of difficult access in endourology. This focuses on anatomical factors that complicate endoscopic management of upper and lower urinary tract diseases and discussing strategies to manage these challenges.</p><p><strong>Recent findings: </strong>Advances in preoperative imaging, three-dimensional reconstruction, flexible digital ureteroscopes, suction-assisted ureteral access sheaths, thulium fibre laser technology, miniaturized percutaneous techniques, and image-guided navigation have significantly improved management in patients with complex anatomy. Improved understanding of congenital and acquired anatomical variations has facilitated individualized surgical planning. Difficult access is a major determinant of operative success and complications in endourology. Anatomical challenges-including narrow ureters, tortuous ureters, lower pole anatomy, calyceal diverticula, horseshoe kidneys, urinary diversion, obesity, spinal deformity, and previous surgery-require preoperative assessment and selective intraoperative strategies. This review summarizes current evidence, practical technical solutions, emerging technologies, and future directions to optimize access, improve stone-free rates, minimize complications, and enhance patient outcomes in complex endourological cases.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"27 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comprehensive Review of Minimally Invasive Surgical Therapies for Voiding Dysfunction in Benign Prostatic Hyperplasia: Past Failures, Contemporary Successes and Future Innovations.","authors":"Shreya Patel, Charles Welliver","doi":"10.1007/s11934-026-01360-1","DOIUrl":"https://doi.org/10.1007/s11934-026-01360-1","url":null,"abstract":"<p><strong>Purpose of review: </strong>Treatments for voiding dysfunction secondary to benign prostatic hyperplasia (BPH) have evolved greatly but also attempted to recapitulate existing ideas. This review will detail the MISTs for BPH through three temporal lenses: past failures and their lessons, contemporary therapies with evidence bases and emerging technologies that are potential futures for minimally invasive BPH treatment.</p><p><strong>Recent findings: </strong>Newer minimally invasive surgical therapies (MISTs) either occupy a new technological niche or refine concepts used by earlier, unsuccessful BPH treatments. Historical permanent stents, balloon dilation, prostatic injection therapies, transurethral needle ablation, and transurethral microwave thermotherapy were limited by complications, inconsistent objective improvement, or high retreatment rates. Contemporary options, including prostatic urethral lift, water-vapor thermal therapy, and drug-coated balloon dilation, demonstrate improved symptom and flow outcomes in selected patients, while temporary nitinol devices and histotripsy continue to evolve. Contemporary devices frequently revisit earlier mechanical, thermal, or dilation-based approaches. Improved materials and delivery systems may reduce prior limitations, but they do not eliminate the need to demonstrate durable efficacy, acceptable retreatment rates, preservation of sexual function, and appropriate patient selection through high-quality long-term studies.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"27 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148863967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mark Ninomiya, Pratham Bhamare, Scott Quarrier, Rajat Jain
{"title":"Disease-Related Etiologies of Nocturia: A Focused Literature Review.","authors":"Mark Ninomiya, Pratham Bhamare, Scott Quarrier, Rajat Jain","doi":"10.1007/s11934-026-01359-8","DOIUrl":"https://doi.org/10.1007/s11934-026-01359-8","url":null,"abstract":"<p><strong>Purpose of review: </strong>Nocturia is a highly prevalent symptom that affects multiple aspects of health. However, it is often underrecognized and undertreated, leading to problems both within the genitourinary system and systemically. The goal of this paper is to further characterize the pathophysiology behind the most common medical factors that contribute to nocturia by performing a focused literature review in a structured format. This will aid clinicians when evaluating and treating patients with nocturia.</p><p><strong>Recent findings: </strong>Based on expert opinion, we recognized six main common pathologies associated with nocturia: obesity, diabetes mellitus, hypertension, obstructive sleep apnea, benign prostatic hyperplasia, and lifestyle habits. Our literature review identified 49 articles including randomized controlled trials, observational studies, systematic reviews, and meta-analyses. Each condition has its own unique pathophysiology that is associated with the development of nocturia. These etiologies also present various ways upon which nocturia can be intervened. These six pathologies are the most common medical etiologies for nocturia based on expert opinion. This paper demonstrates the multifactorial nature of nocturia and highlights assessment and treatment strategies.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"27 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148863999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Steven C Campbell, Samuel K Luketich, Stanley Kandzari
{"title":"The Seniorologists.","authors":"Steven C Campbell, Samuel K Luketich, Stanley Kandzari","doi":"10.1007/s11934-026-01355-y","DOIUrl":"10.1007/s11934-026-01355-y","url":null,"abstract":"<p><p>The urology workforce is aging, with a median provider age of 54 years and approximately one-third over the age of 65. With growing workforce shortages and increasing age-related urologic disease, the need for urologists will continue to increase. Although initiatives such has residency expansion, increased use of advanced practice providers, and alternative certification pathways are being implemented, continued contributions and engagement from senior urologists is becoming increasingly important. These \"Seniorologists\" can offer refined clinical judgement, mentorship, communication skills, professionalism, and fundamentals of medicine such as the physical exam. Although changes in cognitive and physical performance may limit some \"Seniorologists\", these changes vary widely and each individual should be considered on an individual basis. Self-monitoring, ongoing education, objective evaluation, and appropriate scope of clinical responsibilities can be implemented for quality and patient safety. Capable \"Seniorologists\" should be supported by institutions while allowing for flexibility in workload and practice scope. As clinical responsibilities are reduced, \"Seniorologists\" can contribute to the field of urology through teaching, mentoring, and leadership. This type of support benefits the trainees and colleagues, the patients, and the field of urology as a whole. In an era of growing workforce shortages despite growing demands, experienced \"Seniorologists\" remain an invaluable asset whose continued engagement will help shape the future of urology and change patient care.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"27 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148789351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jessica King, Carolyn D Brookhart, Chris Staniorski, Andrea Badillo, Marc Levitt, Allison Mayhew, Briony K Varda
{"title":"A Multidisciplinary Perspective on the Evaluation and Management of the Müllerian System with Attention to Urologic Considerations in Patients Born with Persistent Cloaca.","authors":"Jessica King, Carolyn D Brookhart, Chris Staniorski, Andrea Badillo, Marc Levitt, Allison Mayhew, Briony K Varda","doi":"10.1007/s11934-026-01353-0","DOIUrl":"https://doi.org/10.1007/s11934-026-01353-0","url":null,"abstract":"<p><strong>Purpose of review: </strong>To perform a detailed review of the current literature on management of the müllerian system with an understanding of urologic considerations in patients with persistent cloaca.</p><p><strong>Recent findings: </strong>Recent literature has emphasized the co-occurrence of müllerian and urologic anomalies in children with persistent cloaca emphasizing their shared embryologic origins. Review of imaging approaches has emphasized the difficulty in accurately delineating müllerian anatomy pre-pubertally and the importance of follow-up for management of potential sequelae arising pubertally. Important aspects of care are changing such as a shift to using CIC for management of hydrocolpos as well as differing approaches to reconstruction such as timing of vaginal replacement and use of graft materials. However, high-quality literature to guide management of these critical aspects of care are lacking. The müllerian and urologic systems are essential to consider throughout childhood to preserve renal function, maximize reproductive potential and improve quality of life. High-quality studies are needed to guide evidence-based practice.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"27 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148789357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Agustin Perez Londono, Aditi Yellu, Riley Hanes, Brendan K Wallace, Arvin K George, Soum D Lokeshwar
{"title":"Beyond Surgical Technique: Evolving Strategies to Reduce Urinary Incontinence After Radical Prostatectomy.","authors":"Agustin Perez Londono, Aditi Yellu, Riley Hanes, Brendan K Wallace, Arvin K George, Soum D Lokeshwar","doi":"10.1007/s11934-026-01356-x","DOIUrl":"https://doi.org/10.1007/s11934-026-01356-x","url":null,"abstract":"<p><p>Radical Prostatectomy is one of the standard treatments for localized clinically significant prostate cancer (PCa). However, despite advances in surgical technique such as the robotic radical prostatectomy (RARP), stress urinary incontinence (SUI) remains a common side effect. Patient counseling should include a discussion of preoperative predictors of incontinence including obesity, larger prostate size and shorter membranous urethral length. To improve surgical outcomes, several management strategies have been developed. These include surgical techniques such as the Rocco Stitch, the Hood-technique, and Retzius-sparing RARP. Novel treatments, devices and multimodal approaches are emerging including prehabilitation, remote and digital pelvic floor muscle training, novel neuromodulation, automated artificial urinary sphincters, and surgical augmentation of the vesicourethral anastomosis. These new strategies offer the potential for improved continence without compromising oncologic outcomes. Overall, incontinence prevention and treatment after RARP is becoming increasingly individualized with many options available for clinicians to offer to patients. Continued innovation and discovery in functional recovery after RP are imperative.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"27 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148789419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of Hyperbaric Oxygen Therapy in Radiation Cystitis.","authors":"Stephen A Harrington, Rachel A Moses","doi":"10.1007/s11934-026-01350-3","DOIUrl":"https://doi.org/10.1007/s11934-026-01350-3","url":null,"abstract":"<p><strong>Purpose of the review: </strong>To summarize existing literature on the outcomes of Hyperbaric Oxygen (HBO<sub>2</sub>) therapy for RC and focus on recent updates since the original 2018 scoping review.</p><p><strong>Recent findings: </strong>The literature continues to support HBO<sub>2</sub>'s effectiveness at improving gross hematuria with recent studies showing at least a partial response in 66-100% of patients. Recent data further show an improvement in both urinary symptoms and overall quality of life measures. Data further shows that HBO<sub>2</sub> is safe and adverse events are usually associated with barotrauma, particularly otic barotrauma. Recent data continue to show that HBO<sub>2</sub> therapy is a safe and cost-effective tool for treating patients with radiation cystitis-induced gross hematuria. The majority of patients treated with HBO<sub>2</sub> will experience at least a partial response. Further data is needed to evaluate the optimum timing, dose, and duration of HBO<sub>2</sub> treatment.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"27 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148789390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gantapong Sainont, Michael Uy, Pankaj N Maheshwari, Hsiang Ying Lee, Daniele Castellani, Yasser A Noureldin, Brett A Johnson, Horacio Sanguinetti, Khurshid R Ghani
{"title":"Smart Lithotripsy: Lasers, Energy Sources and Efficiency.","authors":"Gantapong Sainont, Michael Uy, Pankaj N Maheshwari, Hsiang Ying Lee, Daniele Castellani, Yasser A Noureldin, Brett A Johnson, Horacio Sanguinetti, Khurshid R Ghani","doi":"10.1007/s11934-026-01354-z","DOIUrl":"10.1007/s11934-026-01354-z","url":null,"abstract":"<p><strong>Purpose of review: </strong>To examine the evidence on contemporary lasers and provide a practical framework for platform selection, parameter optimization, and thermal safety based on the principles of smart lithotripsy.</p><p><strong>Recent findings: </strong>Holmium: yttrium-aluminum-garnet (Ho:YAG) remains versatile for fragmentation and dusting, whereas thulium fiber laser (TFL) provides efficient fine-particle dusting with limited retropulsion. Pulsed thulium: YAG (p-Tm:YAG) shows an intermediate profile between Ho:YAG and TFL, but clinical evidence on lithotripsy outcomes is limited. Higher power settings with Ho:YAG may accelerate ablation, but have to be used carefully with high flow rates and access sheaths. For TFL, high-power settings have not been shown to shorten operative time or improve stone-free outcomes and may increase thermal risk. Future systems may incorporate stone recognition, composition prediction, and tissue protection. There is no ideal laser for every clinical scenario. Urologists should match the platform, settings, and treatment strategy to the intended endpoint, whether fragmentation with active extraction or dusting with passive clearance.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"27 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13478032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148757750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veronica S Zhang, Shirley L Wang, Benjamin Schurhamer
{"title":"Review of Neurovascular Reconstruction During Robotic-Assisted Laparoscopic Radical Prostatectomy.","authors":"Veronica S Zhang, Shirley L Wang, Benjamin Schurhamer","doi":"10.1007/s11934-026-01349-w","DOIUrl":"https://doi.org/10.1007/s11934-026-01349-w","url":null,"abstract":"<p><strong>Purpose of review: </strong>This manuscript provides a narrative review of techniques of neurovascular reconstruction during robotic-assisted laparoscopic radical prostatectomy (RALP).</p><p><strong>Recent findings: </strong>Historic techniques of neurovascular reconstruction, including autologous nerve grafting and neurorrhaphy, have been shown to be feasible in patients in early pilot studies. More recently, perinatal tissue allografts have been studied, with studies supporting earlier recovery of potency or continence. We review historic experimental techniques which are less frequently employed, including nerve grafting and end-to-end nerve anastomosis. More recently, perinatal tissue allograft wraps placed over the neurovascular bundles (NVB) have been demonstrated to be feasible, requiring minimal additional operative time. Existing studies demonstrate earlier return to potency or continence for men with good preoperative function. While further prospective research is needed to validate these findings, this represents a feasible method which may accelerate recovery for men undergoing RALP.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"27 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13476334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148758170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lingmin Song, Margaret Meagher, Ava Saidian, Amirali Salmasi, Sarah Azari, Mai Dabbas, Aditya Bagrodia
{"title":"Intravesical Recurrence of Upper Tract Urothelial Carcinoma: Strategies for Prevention.","authors":"Lingmin Song, Margaret Meagher, Ava Saidian, Amirali Salmasi, Sarah Azari, Mai Dabbas, Aditya Bagrodia","doi":"10.1007/s11934-026-01331-6","DOIUrl":"10.1007/s11934-026-01331-6","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review focuses on intravesical recurrence (IVR) of upper tract urothelial carcinoma (UTUC).</p><p><strong>Recent findings: </strong>We explore epidemiology, risk factors, mechanisms of tumor cell seeding, molecular pathways, genetic predispositions, and related factors of UTUC. Diagnostic techniques, strategies managing disease and reducing recurrence, as well as controversies and challenges in UTUC management are discussed. By synthesizing the latest research findings, this review aims to provide a comprehensive understanding of UTUC IVR which can guide clinical practice and future research efforts.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"27 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13468967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148722290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}