Current Urology Reports最新文献_第10页

Technical Aspects and Clinical Outcomes of Robotic Ureteroscopy: Is It Ready for Primetime? 机器人输尿管镜的技术方面和临床结果:它准备好了吗?

IF 2.6 2区医学

Current Urology Reports Pub Date : 2023-08-01 DOI: 10.1007/s11934-023-01167-4

Mriganka Mani Sinha, Vineet Gauhar, Lazaros Tzelves, Tzevat Tefik, Rifat Burak Ergul, Patrick Juliebø-Jones, Bhaskar K Somani

{"title":"Technical Aspects and Clinical Outcomes of Robotic Ureteroscopy: Is It Ready for Primetime?","authors":"Mriganka Mani Sinha, Vineet Gauhar, Lazaros Tzelves, Tzevat Tefik, Rifat Burak Ergul, Patrick Juliebø-Jones, Bhaskar K Somani","doi":"10.1007/s11934-023-01167-4","DOIUrl":"https://doi.org/10.1007/s11934-023-01167-4","url":null,"abstract":"Purpose of review: Robotic surgery in urology has already been widely employed in robotic-assisted laparoscopic surgery for minimally invasive procedures (MIS). We wanted to analyse rapidly developing robotic ureteroscopy (RoboURS) for the treatment of renal stone disease.Recent findings: A comprehensive literature review was performed for technical aspects and clinical outcomes of RoboURS. RoboURS has made significant breakthroughs with each model proving that this technology improves ergonomics and supports surgeon and instrument longevity while minimising musculoskeletal issues in retrograde intra-renal surgery (RIRS). Further randomised controlled trials are required to compare the efficacy of RoboURS vs manual flexible ureteroscopy (FURS). The cost-effectiveness will also need to be assessed prior to widespread acceptance into urological infrastructure and mainstream practice. RoboURS continues to evolve despite the limitations of infrastructure and cost-effectiveness. It holds the promise of a better future for surgeon longevity, reduced peri-operative morbidity and better workplace environment.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"24 8","pages":"391-400"},"PeriodicalIF":2.6,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9943793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound-Guided PCNL - Why Are We Still Performing Exclusively Fluoroscopic Access? 超声引导的PCNL -为什么我们仍然只进行透视访问?

IF 2.6 2区医学

Current Urology Reports Pub Date : 2023-07-01 DOI: 10.1007/s11934-023-01163-8

David T Tzou, Thomas O Tailly, Karen L Stern

引用次数: 0

Review of Active Surveillance in Underrepresented and High-Risk Populations: Feasibility and Safety. 在代表性不足和高危人群中主动监测的综述:可行性和安全性。

IF 2.6 2区医学

Current Urology Reports Pub Date : 2023-07-01 DOI: 10.1007/s11934-023-01158-5

John Fastenau, Kunj Jain, Aleksandar Popovic, Evan Kovac

{"title":"Review of Active Surveillance in Underrepresented and High-Risk Populations: Feasibility and Safety.","authors":"John Fastenau, Kunj Jain, Aleksandar Popovic, Evan Kovac","doi":"10.1007/s11934-023-01158-5","DOIUrl":"https://doi.org/10.1007/s11934-023-01158-5","url":null,"abstract":"Purpose of review: The purpose of this review is to investigate the current use and effectiveness of active surveillance (AS) for clinical low-risk prostate cancer (PCa) in men considered to be \"high-risk\" based on the factors of race, genetics, healthcare access, and socioeconomic status.Recent findings: Advances in molecular biomarkers and imaging have improved the detection, risk stratification, and treatment of PCa. Still, overdiagnosis and overtreatment of indolent disease remain a concern. AS is therefore the preferred option for clinical low-risk disease. Yet, because of the variability in PCa presentation based on the aforementioned environmental and genetic factors, the question remains: Is active surveillance a safe option for everyone? Provider hesitancy should not necessarily exclude high-risk men from participating in AS. Rather, clinicians should employ shared decision-making, sound clinical judgment, and stringent follow-up in order to effectively counsel AS candidates and optimize AS-related outcomes in \"high-risk\" individuals.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"24 7","pages":"307-315"},"PeriodicalIF":2.6,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9633014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Metastasis-Directed Therapy for Oligometastatic Castration-Sensitive Prostate Cancer: An Alternative to ADT? 转移导向治疗寡转移性去势敏感前列腺癌:替代ADT?

IF 2.6 2区医学

Current Urology Reports Pub Date : 2023-07-01 DOI: 10.1007/s11934-023-01159-4

Ellen M Cahill, John L Pfail, Melinda Z Fu, Biren Saraiya, Tina Mayer, Ryan D Stephenson, Ronald D Ennis, Lara Hathout, Matthew P Deek, Saum Ghodoussipour, Thomas L Jang

{"title":"Metastasis-Directed Therapy for Oligometastatic Castration-Sensitive Prostate Cancer: An Alternative to ADT?","authors":"Ellen M Cahill, John L Pfail, Melinda Z Fu, Biren Saraiya, Tina Mayer, Ryan D Stephenson, Ronald D Ennis, Lara Hathout, Matthew P Deek, Saum Ghodoussipour, Thomas L Jang","doi":"10.1007/s11934-023-01159-4","DOIUrl":"https://doi.org/10.1007/s11934-023-01159-4","url":null,"abstract":"Purpose of review: The standard treatment of patients with metastatic prostate cancer is systemic treatment with androgen-deprivation therapy (ADT). The spectrum-based model of metastatic disease includes the presence of an oligometastatic state, an intermediary between localized and widespread metastatic disease, in which radical local treatment might improve systemic control. Our purpose is to review the literature on metastasis-directed therapy in the treatment of oligometastatic prostate cancer.Recent findings: Several prospective clinical trials have reported improvements in ADT-free survival and progression-free survival with metastasis-directed therapy of oligometastatic prostate cancer. Retrospective studies have found improvements in oncologic outcomes for patients with oligometastatic prostate cancer undergoing metastasis-directed therapy, and several recent prospective clinical trials have confirmed these results. Advancements in imaging as well as an understanding of the genomics of oligometastatic prostate cancer may allow for better patient selection for metastasis-directed therapy and the potential for cure in selected patients.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"24 7","pages":"299-306"},"PeriodicalIF":2.6,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9621092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of the Renin-Angiotensin System Components in Renal Cell Carcinoma: A Literature Review. 肾素-血管紧张素系统成分在肾细胞癌中的作用:文献综述。

IF 2.6 2区医学

Current Urology Reports Pub Date : 2023-07-01 DOI: 10.1007/s11934-023-01160-x

Thiago Camelo Mourão, Stephania Martins Bezerra, Victor Espinheira Santos, Eder Silveira Brazão, Walter Henriques da Costa, Stênio de Cássio Zequi

{"title":"Role of the Renin-Angiotensin System Components in Renal Cell Carcinoma: A Literature Review.","authors":"Thiago Camelo Mourão, Stephania Martins Bezerra, Victor Espinheira Santos, Eder Silveira Brazão, Walter Henriques da Costa, Stênio de Cássio Zequi","doi":"10.1007/s11934-023-01160-x","DOIUrl":"https://doi.org/10.1007/s11934-023-01160-x","url":null,"abstract":"Purpose of review: The physiological aspects of renin-angiotensin system (RAS) components are described in this review. Additionally, we present the main results of studies that could indicate an association between alterations in these components and cancer, particularly renal cell carcinoma (RCC).Recent findings: The RAS undergoes a series of homeostatic and modulatory processes that extend to hypertrophy, hyperplasia, fibrosis, and remodeling, as well as angiogenesis, pro-inflammatory responses, cell differentiation, stem cell programming, and hematopoiesis. The link between cancer-related inflammation and RAS signaling converge in the response to tumor hypoxia and oxidative stress mechanisms, particularly with the angiotensin type 1 receptor leading to activation of transcription factors such as nuclear factor κB (NF-κB), as well as members of the signal transducer and activation of transcription (STAT) family and HIF1⍺. Dysregulation of the physiological actions of RAS in the microenvironment of inflammation and angiogenesis promotes tumor cell growth.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"24 7","pages":"345-353"},"PeriodicalIF":2.6,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9621578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imaging Techniques to Determine Degree of Sarcopenia and Systemic Inflammation in Advanced Renal Cell Carcinoma. 影像学技术测定晚期肾细胞癌中肌肉减少和全身性炎症程度。

IF 2.6 2区医学

Current Urology Reports Pub Date : 2023-07-01 DOI: 10.1007/s11934-023-01157-6

Benjamin N Schmeusser, Adil A Ali, Florian J Fintelmann, Jose M Garcia, Grant R Williams, Viraj A Master, Sarah P Psutka

{"title":"Imaging Techniques to Determine Degree of Sarcopenia and Systemic Inflammation in Advanced Renal Cell Carcinoma.","authors":"Benjamin N Schmeusser, Adil A Ali, Florian J Fintelmann, Jose M Garcia, Grant R Williams, Viraj A Master, Sarah P Psutka","doi":"10.1007/s11934-023-01157-6","DOIUrl":"https://doi.org/10.1007/s11934-023-01157-6","url":null,"abstract":"Purpose of review: The purpose of this review is to provide an up-to-date understanding regarding the literature on sarcopenia and inflammation as prognostic factors in the context of renal cell carcinoma (RCC).Recent findings: Sarcopenia is increasingly recognized as a prognostic factor in RCC. Emerging literature suggests monitoring quantity of muscle on successive imaging and examining muscle density may be additionally informative. Inflammation has prognostic ability in RCC and is also considered a key contributor to development and progression of both RCC and sarcopenia. Recent studies suggest these two prognostic factors together may provide additional prognostic ability when used in combination. Ongoing developments include quality control regarding sarcopenia research and imaging, improving understanding of muscle loss mechanisms, and enhancing clinical incorporation of sarcopenia via improving imaging analysis practicality (i.e., artificial intelligence) and feasible biomarkers. Sarcopenia and systemic inflammation are complementary prognostic factors for adverse outcomes in patients with RCC. Further study on high-quality sarcopenia assessment standardization and expedited sarcopenia assessment is desired for eventual routine clinical incorporation of these prognostic factors.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"24 7","pages":"317-334"},"PeriodicalIF":2.6,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10330545/pdf/nihms-1900776.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9822268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Residency Surgical BPH Training Paradigms from MIST to HOLEP. 从MIST到HOLEP的住院医师外科BPH培训范式。

IF 2.6 2区医学

Current Urology Reports Pub Date : 2023-06-01 DOI: 10.1007/s11934-023-01153-w

Thaiphi Luu, Ricardo R Gonzalez

{"title":"Residency Surgical BPH Training Paradigms from MIST to HOLEP.","authors":"Thaiphi Luu, Ricardo R Gonzalez","doi":"10.1007/s11934-023-01153-w","DOIUrl":"https://doi.org/10.1007/s11934-023-01153-w","url":null,"abstract":"Purpose of review: Benign prostatic hyperplasia (BPH) is a common medical condition of older men that often requires medical or surgical therapy. Surgical options for BPH have grown exponentially over the last two decades. The numerous options and/or lack of access to them can make it challenging for new trainees to gain proficiency. We examine the literature for available BPH surgical simulators, learning curves, and training pathways.Recent findings: Each BPH surgical therapy has a learning curve which must be overcome. There is an abundance of TURP simulators which have shown face, content, and construct validity in the literature. Similarly, laser therapies have validated simulators. Newer technologies do have available simulators, but they have not been validated. There are strategies to improve learning and outcomes, such as having a structured training program. Simulators are available for BPH surgical procedures and some have been implemented in urology residencies. It is likely that such simulation may make urologists more facile on their learning curves for newer technologies. Further studies are needed. Future directions may include integration of simulator technology into training pathways that include surgical observation and proctorship.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"24 6","pages":"261-269"},"PeriodicalIF":2.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9457728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Advancing Urology Resident Surgical Autonomy. 推进泌尿外科住院医师的手术自主权。

IF 2.5 2区医学

Current Urology Reports Pub Date : 2023-06-01 Epub Date: 2023-03-14 DOI: 10.1007/s11934-023-01152-x

Anh T Nguyen, Devashish J Anjaria, Hossein Sadeghi-Nejad

引用次数: 0

An Update of In Vivo Application of Artificial Intelligence and Robotics for Percutaneous Nephrolithotripsy: Results from a Systematic Review. 人工智能和机器人技术在经皮肾镜碎石术中的体内应用进展:一项系统综述的结果。

IF 2.6 2区医学

Current Urology Reports Pub Date : 2023-06-01 DOI: 10.1007/s11934-023-01155-8

Vineet Gauhar, Carlo Giulioni, Nariman Gadzhiev, Virgilio De Stefano, Jeremy Yuen-Chun Teoh, Ho Yee Tiong, Kazumi Taguchi, Giulio Milanese, Andrea Benedetto Galosi, Bhaskar Kumar Somani, Daniele Castellani

{"title":"An Update of In Vivo Application of Artificial Intelligence and Robotics for Percutaneous Nephrolithotripsy: Results from a Systematic Review.","authors":"Vineet Gauhar, Carlo Giulioni, Nariman Gadzhiev, Virgilio De Stefano, Jeremy Yuen-Chun Teoh, Ho Yee Tiong, Kazumi Taguchi, Giulio Milanese, Andrea Benedetto Galosi, Bhaskar Kumar Somani, Daniele Castellani","doi":"10.1007/s11934-023-01155-8","DOIUrl":"https://doi.org/10.1007/s11934-023-01155-8","url":null,"abstract":"Purpose of review: Kidney puncture is a key step in percutaneous nephrolithotomy (PCNL). Ultrasound/fluoroscopic-guided access to the collecting systems is commonly used in PCNL. Performing a puncture is often challenging in kidneys with congenital malformations or complex staghorn stones. We aim to perform a systematic review to examine data on in vivo applications, outcomes, and limitations of using artificial intelligence and robotics for access in PCNL.Recent findings: The literature search was performed on November 2, 2022, using Embase, PubMed, and Google Scholar. Twelve studies were included. 3D in PCNL is useful for image reconstruction but also in 3D printing with definite benefits seen in improving anatomical spatial understanding for preoperative and intraoperative planning. 3D model printing and virtual and mixed reality allow for an enhanced training experience and easier access which seems to translate into a shorter learning curve and better stone-free rate compared to standard puncture. Robotic access improves the accuracy of the puncture for ultrasound- and fluoroscopic-guided access in both supine and prone positions. The potential advantage robotics are using artificial intelligence to do remote access, reduced number of needle punctures, and less radiation exposure during renal access. Artificial intelligence, virtual and mixed reality, and robotics may play a key role in improving PCNL surgery by enhancing all aspects of a successful intervention from entry to exit. There is a gradual adoption of this newer technology into clinical practice but is yet limited to centers with access and the ability to afford this.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"24 6","pages":"271-280"},"PeriodicalIF":2.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9954476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Single-Use Ureteroscopy and Environmental Footprint: Review of Current Evidence. 一次性输尿管镜检查与环境足迹:当前证据综述。

IF 2.6 2区医学

Current Urology Reports Pub Date : 2023-06-01 DOI: 10.1007/s11934-023-01154-9

George Brown, Andrea Ong, Patrick Juliebø-Jones, Niall F Davis, Andreas Skolarikos, Bhaskar Somani

{"title":"Single-Use Ureteroscopy and Environmental Footprint: Review of Current Evidence.","authors":"George Brown, Andrea Ong, Patrick Juliebø-Jones, Niall F Davis, Andreas Skolarikos, Bhaskar Somani","doi":"10.1007/s11934-023-01154-9","DOIUrl":"https://doi.org/10.1007/s11934-023-01154-9","url":null,"abstract":"Purpose of review: Ureteroscopy is a well-established treatment modality for kidney and ureteric calculi in addition to playing a key role in upper tract cancer diagnostics. Traditional reusable flexible ureteroscopes are technologically advanced and expensive pieces of equipment that require repeat sterilisation and periodical repair. These issues have led to the development of single-use flexible ureteroscopes that are disposed of after each case. Whilst this may be advantageous in many respects, the environmental impact of such technology is yet to be fully determined. The aim of this review is to therefore identify and summarise the available literature concerning the environmental footprint of single-use ureteroscopy.Recent findings: To identify the latest research on this topic, a systematic search of world literature was conducted using the Medline, Embase, and PsycINFO databases. PRISMA guidelines were followed and articles were assessed by all authors and relevant study results were included in a narrative format. Only one relevant article was identified and included. This study found that a single-use flexible ureteroscope (LithoVueTM by Boston Scientific) generated an equivalent amount of carbon dioxide per case to a contemporary reusable flexible ureteroscope. Literature concerning the environmental footprint of single-use ureteroscopy is worryingly lacking. No conclusions can be definitively drawn from a single study and further research is imperative given the global climate crisis and the significant contribution that healthcare services have to the environmental problem.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"24 6","pages":"281-285"},"PeriodicalIF":2.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9455993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2