Kanna Tatsumi, Yoshitomo Honda, Masato Nakagawa, Zi Deng, Yosuke Miyaji, Yue Zhou, Aki Nishiura
{"title":"Green tea catechin at a daily intake level suppresses root resorption while maintaining intrusive tooth movement in rat model.","authors":"Kanna Tatsumi, Yoshitomo Honda, Masato Nakagawa, Zi Deng, Yosuke Miyaji, Yue Zhou, Aki Nishiura","doi":"10.4012/dmj.2025-282","DOIUrl":"10.4012/dmj.2025-282","url":null,"abstract":"<p><p>External apical root resorption (EARR) is a common complication of orthodontic treatment. Nevertheless, effective preventive strategies have not yet been established. Here, we demonstrated that administration of green tea catechin (epigallocatechin gallate: EGCG), at concentrations equivalent to habitual human daily intake when adjusted for rat body weight, prevented root resorption while preserving tooth movement in rats. An L-loop orthodontic appliance was used to induce vertical intrusive tooth movement for the maxillary first molar; EGCG was administered at doses of 1 and 2 mg every other day for 14 days (without EGCG for control). Tooth movement and root resorption were assessed using micro-computed tomography (µCT) as well as histological staining [hematoxylin and eosin (H-E) and tartrate-resistant acid phosphatase (TRAP)]. Despite no impairment in tooth movement in all groups, root resorption was significantly suppressed in the EGCG-administered groups. These findings suggest that habitual consumption of tea containing EGCG at daily concentrations may provide safe and effective strategies for orthodontic treatment.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"177-185"},"PeriodicalIF":1.8,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147303377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sang-Hyun Cho, Min-Yong Lee, Ji-Eun Kim, Jae-Sung Kwon
{"title":"Development of a bioactive hydroxyapatite concentration gradient double hydroxyapatite/titanium dioxide coating on TiO<sub>2</sub> core block bone.","authors":"Sang-Hyun Cho, Min-Yong Lee, Ji-Eun Kim, Jae-Sung Kwon","doi":"10.4012/dmj.2025-222","DOIUrl":"10.4012/dmj.2025-222","url":null,"abstract":"<p><p>There is an increasing demand for bone graft procedures to create sufficient bone volume for implant fixture placement. Among various techniques, block bone grafting is considered a favorable option for both horizontal and vertical augmentation. To meet the required physical and biological characteristics, a novel hydroxyapatite (HA)-coated titanium dioxide (TiO<sub>2</sub>) core block bone was developed in this study. The coating layer was designed with an HA concentration gradient to achieve superior compressive strength and wear resistance. The concentration gradient was confirmed by scanning electron microscopy/energy-dispersed X-ray spectroscopy, and coating stability was demonstrated through scratch testing. Furthermore, alizarin red S staining revealed that the HA gradient layer retained bone formation compared to a single-layer HA coating. Taken together, the developed doubled-layered HA gradient TiO<sub>2</sub> block bone shows strong potential as a substitute for conventional block bone grafts.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"159-168"},"PeriodicalIF":1.8,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147303312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of phosphate solution pH on the setting behavior and hemocompatibility of α-tricalcium phosphate granular cement.","authors":"Abdulrahman Diabi, Ryo Kishida, Kunio Ishikawa","doi":"10.4012/dmj.2025-164","DOIUrl":"10.4012/dmj.2025-164","url":null,"abstract":"<p><p>Calcium phosphate granules can set when mixed with acidic phosphate solutions, forming an interconnected porous structure suitable for bone regeneration. However, the high acidity of these formulations may compromise their biocompatibility. This study investigates the feasibility of using less acidic phosphate solutions for α-tricalcium phosphate (α-TCP) granular cement to improve biocompatibility while ensuring sufficient setting. α-TCP granules were mixed with sodium phosphate solutions adjusted to pH 1, 2, 3, 5, and 7. Raising the solution pH prolonged the setting time while simultaneously reducing the hemolytic potential of the granular cement. Notably, no hemolysis was observed at pH≥3. All the granules set, forming interconnected porous structures and exhibiting partial conversion to calcium-deficient hydroxyapatite and octacalcium phosphate. These results demonstrate that using phosphate solutions with pH≥3 is an effective approach to optimize both the setting behavior and biocompatibility of α-TCP granular cement for clinical applications.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"152-158"},"PeriodicalIF":1.8,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147275976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Air abrasion device versus sandblasting device for surface pretreatment of CAD-CAM prosthetic materials.","authors":"Kentaro Nakajima, Yoshiki Ishida, Daisuke Miura, Yasuhiro Hotta, Akikazu Shinya","doi":"10.4012/dmj.2025-297","DOIUrl":"10.4012/dmj.2025-297","url":null,"abstract":"<p><p>This study evaluated the effects of various surface pretreatments using chairside air abrasion with water injection or laboratory sandblasting devices on the shear bond strength of resin luting agents to three CAD-CAM prosthetic materials: resin composites, glass ceramics, and zirconia. Pretreatments included air abrasion with water injection (29 µm or 53 µm alumina or bioactive glass powder), conventional sandblasting with 50 µm alumina, and hydrofluoric acid etching for glass ceramics. Specimens were prepared after embedding the blocks. Surface roughness was measured after pretreatment, and shear bond strength was tested following cementation. Failure modes were analyzed using an optical profilometer. Results showed that air abrasion with 50 µm alumina, whether using a chairside device with water injection or a laboratory sandblasting device, produced comparable bond strength. These findings suggest that chairside air abrasion with 50 µm alumina is a clinically viable alternative to laboratory sandblasting for surface treatment of CAD-CAM prosthetic materials.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"193-202"},"PeriodicalIF":1.8,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147275968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of surface treatments on shear bond strength between CAD/CAM glass fiber-reinforced composite block and veneering indirect composite material.","authors":"Satomi Arai, Kei Kubochi, Keisuke Hoshino, Daishi Nakase, Ralf J Kohal, Futoshi Komine","doi":"10.4012/dmj.2025-185","DOIUrl":"10.4012/dmj.2025-185","url":null,"abstract":"<p><p>This study aimed to evaluate the effect of different surface treatments and artificial aging on the shear bond strength between a CAD/CAM glass fiber-reinforced composite (FRC) block and a veneering indirect composite material. Four surface treatments-no surface treatment (NT), airborne-particle abrasion (AB), tribochemical silica coating (ROC), and hydrofluoric acid etching (HF)-were assessed with and without silane application. Specimens were subjected to thermocycling and mechanical loading to simulate aging. Shear bond strength was measured, and failure modes were analyzed using scanning electron microscopy and energy-dispersive X-ray spectroscopy. The AB group exhibited the highest bond strength without silane application. The ROC group combined with silane yielded the highest bond strength, particularly after thermal cycling. Mechanical loading reduced the effectiveness of silane application. These findings indicate that tribochemical silica coating followed by silanization provides a superior and durable bond between FRC blocks and veneering indirect composite materials.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"220-227"},"PeriodicalIF":1.8,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147354150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of atmospheric pressure plasma irradiation on adhesive penetration into gaps.","authors":"Fuko Kimura, Mizuki Inaba, Yuki Kurisu, Yasuki Uchida, Hiroyasu Koizumi, Takayuki Yoneyama, Yasuhiro Namura","doi":"10.4012/dmj.2025-186","DOIUrl":"10.4012/dmj.2025-186","url":null,"abstract":"<p><p>This study evaluated the effects of atmospheric nitrogen plasma on shear load resistance (SLR), penetration distance, and penetration area of adhesives used in the partial repair of bonded lingual retainers. Bonding gaps of 50, 100, and 150 μm were prepared between bovine enamel and composite resin, followed by plasma irradiation, and the surface free energy of the gaps was assessed. After adhesive application to the gap followed by curing the adhesive, the SLR, adhesive penetration distance, and penetration area of the treated surfaces were measured. In addition, these measurements were statistically compared with those of the untreated group. At 150 μm, plasma treatment significantly increased SLR, particularly with the 4-META/MMA-TBB resin adhesive. For all gap thicknesses, plasma treatment significantly enhanced the penetration distance and penetration area of the adhesives. These results suggest that plasma irradiation is an effective process for the partial repair of bonded retainers.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"214-219"},"PeriodicalIF":1.8,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146164564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biomaterial properties of octacalcium phosphate (OCP) and its collagen composite bone substitute.","authors":"Osamu Suzuki, Tadashi Kawai, Ryo Hamai","doi":"10.4012/dmj.2025-338","DOIUrl":"10.4012/dmj.2025-338","url":null,"abstract":"<p><p>Octacalcium phosphate (OCP), a precursor to hydroxyapatite (HA), has recently garnered significant interest from biomaterial researchers both domestically and internationally because OCP has been confirmed to possess the capacity to activate bone-related cells, such as osteoblasts and osteoclasts, and to exhibit high osteogenic potential and bioresorbability if implanted in bone defects. Since OCP contains a large amount of water molecules in its structure, it cannot be sintered as a single crystal phase. Therefore, efforts have been paid to develop molding OCP through combining polymer materials, such as collagen (Col). OCP/Col has been approved in Japan for clinical application as a bone substitute material for combination uses with dental implants in the oral and maxillofacial surgery fields. The aim of this review is to summarize the process leading to the OCP/Col fabrication, as well as the clinical application of OCP/Col, focusing on these materials from chemical, physical, and biological perspectives as biomaterials.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"113-121"},"PeriodicalIF":1.8,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147354117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antibacterial, mechanical, and bonding properties of self-adhesive resin composites containing surface pre-reacted glass ionomer filler.","authors":"Tuba Çetin, Haruaki Kitagawa, Satoshi Yamaguchi, Mahmut Kusdemir, Jun-Ichi Sasaki, Satoshi Imazato","doi":"10.4012/dmj.2025-287","DOIUrl":"10.4012/dmj.2025-287","url":null,"abstract":"<p><p>Surface pre-reacted glass ionomer (S-PRG) filler is a bioactive material capable of releasing multiple ions, including antibacterial borate ions. A self-adhesive resin composite containing S-PRG filler (Fit Sa; FS) has been reported to release high levels of borate ions. This study investigated the mechanical, bonding, and antibacterial properties of FS compared with other self-adhesive resin composites, conventional resin composites, and universal adhesive systems. The flexural strength of FS was comparable to that of conventional flowable composites and greater than that of several self-adhesive resin composites. The microtensile bond strength of FS was similar to that of a conventional self-etching adhesive system, whereas other self-adhesive resin composites showed lower strength or tended to fail prematurely. FS significantly inhibited Streptococcus mutans, while the other self-adhesive resin composites exhibited no antibacterial effect. These findings indicate that FS exhibits acceptable mechanical properties, bonding ability, and antibacterial potential, supporting its applicability for clinical use.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"186-192"},"PeriodicalIF":1.8,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147275972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ikram Aqel Salim, Thiago Henrique Scarabello Stape, Roda Seseogullari-Dirihan, Mustafa Murat Mutluay, Arzu Tezvergil-Mutluay
{"title":"Effect of solvent pretreatments on trans-dentinal cytotoxicity of bioactive materials.","authors":"Ikram Aqel Salim, Thiago Henrique Scarabello Stape, Roda Seseogullari-Dirihan, Mustafa Murat Mutluay, Arzu Tezvergil-Mutluay","doi":"10.4012/dmj.2025-102","DOIUrl":"10.4012/dmj.2025-102","url":null,"abstract":"<p><p>This study evaluated the effect of solvent-based dentin pretreatments containing dimethyl sulfoxide (DMSO) and/or ethanol on trans-dentinal cell viability of bioactive materials in simulated deep clinical cavities. Dentin discs (300 μm) were prepared, balanced among groups according to dentin permeability and autoclaved. Three-dimensional cultures of odontoblast-like cells were transferred to the pulpal aspect of dentin discs inside perfusion split-chambers designed for trans-dentinal cytotoxicity test following ISO 7405 standards. Dentin pretreatments were composed of ethanol (EtOH), DMSO, their 50% (v/v) aqueous dilutions and 50% (v/v) DMSO/EtOH. Pretreatments (1.5 μL) were applied on cell-seeded dentin discs and a 1-mm increment of one of three bioactive materials: a light-curable methacrylate-based silicate (TheraCal), a mineral trioxide aggregate (MTA) or an experimental pre-reacted glass-ionomer filler (S-PRG). Cell viability was analyzed spectrometrically according to the MTT test and cytotoxicity levels were classified following ISO 7405. TheraCal was considered severely cytotoxic, MTA moderately cytotoxic and S-PRG non-cytotoxic. Assessment of cell damage by solvents was ranked as EtOH=EtOH/H<sub>2</sub>O>DMSO>DMSO/EtOH=DMSO/H<sub>2</sub>O. The light-curable methacrylate-based silicate was the only material with considerable trans-dentinal cytotoxicity. While ethanol was harmful to odontoblast-like cells, DMSO had a minor role in cytotoxic responses used alone or combined to bioactive materials. Solvents must be considered for safe use during vital-pulp therapy.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"144-151"},"PeriodicalIF":1.8,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147431453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Carbon dots as dual-functional nanoprobes: Fluorescent labeling of polycaprolactone porous microspheres and enhancement of osteogenic differentiation in rBMSCs.","authors":"Fan Shi, Wen Lin, Qiao Zhou, Zhu Zhu, Xin Song","doi":"10.4012/dmj.2025-159","DOIUrl":"10.4012/dmj.2025-159","url":null,"abstract":"<p><p>Fluorescent tracer technology has been widely used in real-time visual tracking of materials or cell dynamic processes in vivo. However, the commonly used fluorescent probes have their own disadvantages when used in biological systems, such as intrinsic photobleaching of organic dyes and the potential biotoxicity of rare-earth nano-particles. To address these problems, we employed fluorescent carbon dots (CDs) with low photobleaching, red emission and good biocompatibility as a dual tool for long-term tracing of polycaprolactone (PCL) porous microspheres and regulating cells osteogenic differentiation. In vitro cell experiments suggested that CDs were nontoxic and could promote osteogenic differentiation of rat bone marrow mesenchymal stem cells (rBMSCs). CDs enhanced biological properties of PCL microspheres and were successfully traced for 3 months by fluorescence-related visual imaging methodology. As a dual-functional tool to trace scaffold behavior for a long time and regulating cells osteogenic differentiation, CDs have important research potential in the field of tissue engineering and regenerative medicine.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"203-213"},"PeriodicalIF":1.8,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147303353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}