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Structural and chemical properties of acellular scaffolds made from bovine ribs. 牛肋骨脱细胞支架的结构与化学性质研究。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-09-04 DOI: 10.4012/dmj.2024-390
Reza Al Fessi, Coen Pramono Danudiningrat, Koichi Kato, Anita Yuliati
{"title":"Structural and chemical properties of acellular scaffolds made from bovine ribs.","authors":"Reza Al Fessi, Coen Pramono Danudiningrat, Koichi Kato, Anita Yuliati","doi":"10.4012/dmj.2024-390","DOIUrl":"10.4012/dmj.2024-390","url":null,"abstract":"<p><p>This study was aimed to analyze the structural and chemical properties of scaffolds prepared using the bovine rib bone. The bovine rib bone was extracted and processed by water jet washing, hydrogen peroxide treatment, and freeze drying to obtain porous scaffolds. Scanning electron microscopy analysis revealed that the scaffold was composed of interconnected trabeculae networks with an average pore diameter of 223 µm. The bulk density was determined to be 0.582 g/cm<sup>3</sup>, and the porosity was 70.3%. X-ray diffraction analysis showed that the scaffold consisted of hydroxyapatite at a low crystallinity. It was further observed that the scaffold contained calcium and phosphate at a Ca/P ratio of 1.68, with a trace of proteins. When the scaffold was soaked in the phosphate buffered saline at 37°C, the weight of the scaffold decreased by 5.5% after 28 days. These results will provide a platform for subsequent processing to fabricate decellularized scaffolds.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"572-578"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fluoride release and strength change of self-adhesive filling materials after storage in water. 自粘填料在水中贮存后的氟释放及强度变化。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-07-17 DOI: 10.4012/dmj.2024-217
Feng Gao, Gabe Chadwell, Qing Hong, Maria Cuevas-Nunez, Kaveh Adel, Marcela R Carrilho, John C Mitchell
{"title":"Fluoride release and strength change of self-adhesive filling materials after storage in water.","authors":"Feng Gao, Gabe Chadwell, Qing Hong, Maria Cuevas-Nunez, Kaveh Adel, Marcela R Carrilho, John C Mitchell","doi":"10.4012/dmj.2024-217","DOIUrl":"10.4012/dmj.2024-217","url":null,"abstract":"<p><p>The introduction of self-adhesive filling materials has shown advantage in clinical use due to reduced procedure time. The newly developed self-adhesive Surefil One (SO) was compared to other current self-adhesive materials Vertise Flow (VF) and GC Fuji II LC (FJ). Shear bond strength (SBS) to dentin, flexural strength and water sorption were measured at 24 h and 4 weeks. Fluoride release was measured up to 4 weeks. SO showed intermediate fluoride-release that was higher than VF, but lower than FJ. SO demonstrated lower flexural strength than VF at 24 h but maintained that same strength to 4 weeks. SO had SBS comparable to FJ and VF at 24 h but it decreased at 4 weeks. Caution should be exercised when selecting and using SO, as well as the other two self-adhesive materials. Further studies are necessary to evaluate the efficacy for their clinical use in direct restorations.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"471-478"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Less grams per square meter of woven reinforced fiber improves the flexural properties and color stability of glass fiber-reinforced plastics used for dental CAD-CAM. 减少每平方米编织增强纤维的克数，提高了用于牙科CAD-CAM的玻璃纤维增强塑料的弯曲性能和颜色稳定性。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-08-13 DOI: 10.4012/dmj.2024-308
Shunsuke Nagata, Yukako Kato, Dai Saito, Masato Somemiya, Norio Hirayama, Yasuhiro Tanimoto
{"title":"Less grams per square meter of woven reinforced fiber improves the flexural properties and color stability of glass fiber-reinforced plastics used for dental CAD-CAM.","authors":"Shunsuke Nagata, Yukako Kato, Dai Saito, Masato Somemiya, Norio Hirayama, Yasuhiro Tanimoto","doi":"10.4012/dmj.2024-308","DOIUrl":"10.4012/dmj.2024-308","url":null,"abstract":"<p><p>This study investigates the effect of the grams per square meter (GSM) of glass fiber woven cloth used as reinforcement on the flexural properties and color stability of glass fiber-reinforced plastics (GFRPs) applied in computer-aided design-computer-aided manufacturing (CAD-CAM) restorations. Two types of GFRPs were fabricated using glass fiber woven cloth with different GSM values (215 and 47 g/m²), which were impregnated with thermoplastic acrylic resin. The control group consisted of acrylic resin without reinforcement, as well as two types of commercially available CAD-CAM GFRPs with a thermosetting epoxy resin matrix. As a result, GFRPs impregnated with thermoplastic acrylic resin showed higher flexural properties than commercially available GFRPs, and a lower GSM provided improved flexural properties and color stability compared with specimens using a higher GSM.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"518-524"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144844838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep learning predicts osteogenic differentiation stages of human mesenchymal stem cells from phase-contrast microscopy images. 深度学习从相差显微镜图像预测人间充质干细胞的成骨分化阶段。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-09-04 DOI: 10.4012/dmj.2025-015
Mizuho Sano, Yuichi Mine, Shota Okazaki, Moeka Kasagawa, Taku Nishimura, Eimi Tabata, Tzu-Yu Peng, Ayano Ueda, Ryota Nomura, Takeshi Murayama
{"title":"Deep learning predicts osteogenic differentiation stages of human mesenchymal stem cells from phase-contrast microscopy images.","authors":"Mizuho Sano, Yuichi Mine, Shota Okazaki, Moeka Kasagawa, Taku Nishimura, Eimi Tabata, Tzu-Yu Peng, Ayano Ueda, Ryota Nomura, Takeshi Murayama","doi":"10.4012/dmj.2025-015","DOIUrl":"10.4012/dmj.2025-015","url":null,"abstract":"<p><p>In this study, we constructed and validated deep learning models capable of predicting the osteogenic differentiation stages of mesenchymal stem cells (MSCs) using only phase-contrast microscopy images. UE7T-13, an immortalized human MSC line, was cultured in osteoinductive medium. Phase-contrast microscopy images were acquired at D0, D1, D5, D10, and D14 of differentiation. Two deep learning models, ResNet-50 and DenseNet-121, were trained to perform multi-class classification of osteogenic differentiation stages. Model performance was evaluated using precision, sensitivity, F1 score, and overall accuracy. The overall accuracy of the ResNet-50 model was 0.700 and that of the DenseNet-121 model was 0.684. The highest F1 scores occurred at D5, which may reflect more distinctive morphological features during mid-stage differentiation. Our results suggest that deep learning has the potential to non-invasively identify osteogenic differentiation stages based on morphological features alone.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"557-563"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reynoutria elliptica extract based denture cleansing materials: Antimicrobial efficacy, biocompatibility, and impact on surface properties. 紫红提取物基义齿清洁材料：抗菌效果、生物相容性及对表面特性的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-09-04 DOI: 10.4012/dmj.2024-377
Song-Yi Yang, Myung-Jin Lee, Min-Kyung Kang
{"title":"Reynoutria elliptica extract based denture cleansing materials: Antimicrobial efficacy, biocompatibility, and impact on surface properties.","authors":"Song-Yi Yang, Myung-Jin Lee, Min-Kyung Kang","doi":"10.4012/dmj.2024-377","DOIUrl":"10.4012/dmj.2024-377","url":null,"abstract":"<p><p>This study investigated the antimicrobial efficacy, biocompatibility, and surface effects of a denture cleanser containing Reynoutria elliptica extract. The cleanser was prepared with extract concentrations of 0, 100, and 150 μg/mL combined with 1% coco betaine as a natural surfactant. Antimicrobial efficacy against Candida albicans was tested, along with evaluations of surface microhardness, roughness, color stability, and solubility of acrylic resin after immersion. Biocompatibility was assessed using an agar diffusion assay and cytotoxicity tests. Results showed that the denture cleanser exhibited significant antimicrobial activity without altering surface properties or causing cytotoxic effects. These findings highlight the potential of denture cleansers formulated with R. elliptica extract to preserve the structural integrity and aesthetics of denture base materials while providing effective antimicrobial protection. This study offers valuable insights for developing natural, biocompatible denture cleansers for safe and effective dental care.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"525-534"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carbon nanohorn coating on titanium promotes M2 macrophage polarization. 钛表面碳纳米角涂层促进M2巨噬细胞极化。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-09-12 DOI: 10.4012/dmj.2025-028
Sadahito Kimura, Eri Hirata, Yuta Takano, Miho Ibi, Natsumi Ushijima, Eijiro Miyako, Masako Yudasaka, Yukari Maeda, Daisuke Konishi, Kiwamu Sakaguchi, Atsuro Yokoyama
{"title":"Carbon nanohorn coating on titanium promotes M2 macrophage polarization.","authors":"Sadahito Kimura, Eri Hirata, Yuta Takano, Miho Ibi, Natsumi Ushijima, Eijiro Miyako, Masako Yudasaka, Yukari Maeda, Daisuke Konishi, Kiwamu Sakaguchi, Atsuro Yokoyama","doi":"10.4012/dmj.2025-028","DOIUrl":"10.4012/dmj.2025-028","url":null,"abstract":"<p><p>This study investigated the effects of carbon nanohorns (CNHs) coated on titanium surfaces on macrophage responses. The CNHs were electrodeposited on titanium discs to create a uniform coating with a thickness of 0.2-0.3 µm. Analysis of macrophages cultured on CNH-modified titanium (CNH/Ti) revealed decreased production of pro-inflammatory cytokines (TNFα and IL6) and increased IL10 gene expression compared to unmodified titanium. Immunofluorescence analysis showed higher expression of the M2 marker CD206 and lower expression of the M1 marker CD86 on the CNH/Ti surfaces. Gene expression analysis indicated downregulation of genes involved in DNA transcription, repair, and replication, correlating with controlled cell proliferation on CNH/Ti. These findings demonstrate that CNH modification on titanium surfaces influences macrophage cytokine production and phenotype marker expression, suggesting its potential application in dental implant development.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"564-571"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145074501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of desensitizing and/or anti-erosive toothpastes combined with mouthrinses on enamel structure and dental pulp fibroblasts viability. 脱敏和/或抗腐蚀牙膏联合漱口水对牙釉质结构和牙髓成纤维细胞活力的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-09-05 DOI: 10.4012/dmj.2024-380
Géssica Lopes, Thainá Pinto, Paula Moreira DE Carvalho, Giovanna Sarra, Kelson Faial, Márcia Marques, Rafael Lima, Roberta D'Almeida-Couto
{"title":"Effects of desensitizing and/or anti-erosive toothpastes combined with mouthrinses on enamel structure and dental pulp fibroblasts viability.","authors":"Géssica Lopes, Thainá Pinto, Paula Moreira DE Carvalho, Giovanna Sarra, Kelson Faial, Márcia Marques, Rafael Lima, Roberta D'Almeida-Couto","doi":"10.4012/dmj.2024-380","DOIUrl":"10.4012/dmj.2024-380","url":null,"abstract":"<p><p>This study evaluated the chemical profile of toothpastes (TPs) and mouthrinses (MRs) and their effects on tooth enamel ultrastructure, and the viability of human dental pulp fibroblasts (hDPF). Four TPs and MRs containing different remineralizing agents (arginine, potassium nitrate, pro arginine, and stannous chloride) were analyzed for pH, titratable acidity (TA), and ion concentrations (Ca<sup>+2</sup>, K<sup>+</sup>, Na<sup>+2</sup>). Enamel ultrastructure was evaluated using Fourier-transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM). Cell viability was assessed after treatments exposure. TPs and MRs had pH values ranging from 4.43 to 8.87, with SnCl<sub>2</sub>-MR showing the highest TA. Alterations in enamel surface were observed with decrease of Amide I, carbonate and potassium peaks. Combinations of TP+MR reduced calcium concentration. Cell viability was reduced as response to all TP+MR combinations, except to ProArg-MR. These findings suggest that combining TPs and MRs may not enhance their effectiveness and could harm enamel and dental pulp cells.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"487-496"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145014047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research trends and mapping knowledge for enamel matrix derivatives in dentistry: A bibliometric and scientometric analysis. 牙釉质基质衍生物的研究趋势和测绘知识：文献计量学和科学计量学分析。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-08-05 DOI: 10.4012/dmj.2025-058
Nuray Ercan
{"title":"Research trends and mapping knowledge for enamel matrix derivatives in dentistry: A bibliometric and scientometric analysis.","authors":"Nuray Ercan","doi":"10.4012/dmj.2025-058","DOIUrl":"10.4012/dmj.2025-058","url":null,"abstract":"<p><p>This bibliometric analysis is aimed at identifying and analyzing the articles on the dental applications of enamel matrix derivatives (EMDs). Data were obtained from the Web of Science and analyzed using the Bibliometrix program. Publications indexed in SCI-Expanded and ESCI under 'Dentistry, Oral Surgery, and Medicine' were included, while non-English and non-article/review types were excluded. A total of 854 articles were reviewed, focusing on: article performance, word analysis, co-citation, and thematic analysis. Data analysis showed a growing number of publications in this field over time. Sculean A emerged as the leading researcher, while the Journal of Clinical Periodontology was the most influential journal. Recent research trends primarily focused on periodontal regeneration. Finally, thematic analysis revealed two motor themes, four niche themes, two emerging/declining themes, and three basic theme clusters. This bibliometric analysis highlights the increasing interest and the emergence of new research trends in the field of EMDs in dentistry.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"507-517"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of chitosan as a novel antimicrobial dental material -Effects of form, molecular weight, and deacetylation degree on its antimicrobial activity against Candida albicans. 壳聚糖作为新型口腔抗菌材料的应用——形态、分子量和去乙酰化程度对其抗白色念珠菌活性的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-08-05 DOI: 10.4012/dmj.2024-372
Kouki Miura, Airi Matsumoto, Yuichi Oogai, Masanobu Nakata, Yoshihiro Nishitani
{"title":"Application of chitosan as a novel antimicrobial dental material -Effects of form, molecular weight, and deacetylation degree on its antimicrobial activity against Candida albicans.","authors":"Kouki Miura, Airi Matsumoto, Yuichi Oogai, Masanobu Nakata, Yoshihiro Nishitani","doi":"10.4012/dmj.2024-372","DOIUrl":"10.4012/dmj.2024-372","url":null,"abstract":"<p><p>Oral candidiasis is a significant health concern, especially for elderly individuals. The present study examined chitosan as a potential antimicrobial dental material for Candida albicans treatment. Four types of chitosan products purified from Chionoecetes opilio and Decapodiformes, with varying weight average molecular weight and degree of deacetylation (DAC) were used. Antimicrobial activity was assessed with fungal viability assays, culture turbidity measurements, and live/dead cell staining, while mechanism of action was determined by examining extracellular adenosine triphosphate (ATP) level, reactive oxygen species (ROS) production, and gene expression changes. All examined products exhibited antimicrobial activity, with Decapodiformes-derived chitosan showing better efficacy. Greater molecular weight was correlated with immediate effects and higher DAC with sustained activity. Chitosan treatment increased extracellular ATP and ROS levels, and suppression of genes involved in mitochondrial biosynthesis and drug resistance. These findings suggest potential use of chitosan as an antimicrobial agent in dental materials for oral candidiasis prevention and treatment.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"497-506"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Water and solute permeability of membranes used in guided bone regeneration-An in vitro study. 引导骨再生中膜的水和溶质渗透性的体外研究。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-09-12 DOI: 10.4012/dmj.2024-371
Radu Ioan Neacsu, Horia Nitu, Anca Sipos, Lucian Barbu-Tudoran, Adrian Nicoara, Amelia Bucur, Alina Ormenisan
{"title":"Water and solute permeability of membranes used in guided bone regeneration-An in vitro study.","authors":"Radu Ioan Neacsu, Horia Nitu, Anca Sipos, Lucian Barbu-Tudoran, Adrian Nicoara, Amelia Bucur, Alina Ormenisan","doi":"10.4012/dmj.2024-371","DOIUrl":"10.4012/dmj.2024-371","url":null,"abstract":"<p><p>Nutrients diffusion through barrier membranes used in guided bone regeneration is much theorized but few data are available so far. In this study, direct measurement of the water and solute permeability coefficients of five commercial barrier membranes was performed and the results were correlated with scanning electron microscopy findings. First the hydraulic permeability was addressed in short (3 h) and extended periods (3 weeks) assays, then the membranes were further investigated for diffusion of selected solutes (glucose and NaCl). The collagen membrane had the highest initial water permeability, 10 times greater than the polylactide one, and 500 times greater than the expanded-PTFE one, all of which decreased significantly over the 3-weeks test period, whereas dense-PTFE membranes were both found impermeable, the results being positively correlated with solute permeability coefficients and convergent with the SEM findings.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"535-546"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145074564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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