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Deep learning predicts osteogenic differentiation stages of human mesenchymal stem cells from phase-contrast microscopy images. 深度学习从相差显微镜图像预测人间充质干细胞的成骨分化阶段。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-09-04 DOI: 10.4012/dmj.2025-015
Mizuho Sano, Yuichi Mine, Shota Okazaki, Moeka Kasagawa, Taku Nishimura, Eimi Tabata, Tzu-Yu Peng, Ayano Ueda, Ryota Nomura, Takeshi Murayama
{"title":"Deep learning predicts osteogenic differentiation stages of human mesenchymal stem cells from phase-contrast microscopy images.","authors":"Mizuho Sano, Yuichi Mine, Shota Okazaki, Moeka Kasagawa, Taku Nishimura, Eimi Tabata, Tzu-Yu Peng, Ayano Ueda, Ryota Nomura, Takeshi Murayama","doi":"10.4012/dmj.2025-015","DOIUrl":"10.4012/dmj.2025-015","url":null,"abstract":"<p><p>In this study, we constructed and validated deep learning models capable of predicting the osteogenic differentiation stages of mesenchymal stem cells (MSCs) using only phase-contrast microscopy images. UE7T-13, an immortalized human MSC line, was cultured in osteoinductive medium. Phase-contrast microscopy images were acquired at D0, D1, D5, D10, and D14 of differentiation. Two deep learning models, ResNet-50 and DenseNet-121, were trained to perform multi-class classification of osteogenic differentiation stages. Model performance was evaluated using precision, sensitivity, F1 score, and overall accuracy. The overall accuracy of the ResNet-50 model was 0.700 and that of the DenseNet-121 model was 0.684. The highest F1 scores occurred at D5, which may reflect more distinctive morphological features during mid-stage differentiation. Our results suggest that deep learning has the potential to non-invasively identify osteogenic differentiation stages based on morphological features alone.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"557-563"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reynoutria elliptica extract based denture cleansing materials: Antimicrobial efficacy, biocompatibility, and impact on surface properties. 紫红提取物基义齿清洁材料：抗菌效果、生物相容性及对表面特性的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-09-04 DOI: 10.4012/dmj.2024-377
Song-Yi Yang, Myung-Jin Lee, Min-Kyung Kang
{"title":"Reynoutria elliptica extract based denture cleansing materials: Antimicrobial efficacy, biocompatibility, and impact on surface properties.","authors":"Song-Yi Yang, Myung-Jin Lee, Min-Kyung Kang","doi":"10.4012/dmj.2024-377","DOIUrl":"10.4012/dmj.2024-377","url":null,"abstract":"<p><p>This study investigated the antimicrobial efficacy, biocompatibility, and surface effects of a denture cleanser containing Reynoutria elliptica extract. The cleanser was prepared with extract concentrations of 0, 100, and 150 μg/mL combined with 1% coco betaine as a natural surfactant. Antimicrobial efficacy against Candida albicans was tested, along with evaluations of surface microhardness, roughness, color stability, and solubility of acrylic resin after immersion. Biocompatibility was assessed using an agar diffusion assay and cytotoxicity tests. Results showed that the denture cleanser exhibited significant antimicrobial activity without altering surface properties or causing cytotoxic effects. These findings highlight the potential of denture cleansers formulated with R. elliptica extract to preserve the structural integrity and aesthetics of denture base materials while providing effective antimicrobial protection. This study offers valuable insights for developing natural, biocompatible denture cleansers for safe and effective dental care.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"525-534"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carbon nanohorn coating on titanium promotes M2 macrophage polarization. 钛表面碳纳米角涂层促进M2巨噬细胞极化。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-09-12 DOI: 10.4012/dmj.2025-028
Sadahito Kimura, Eri Hirata, Yuta Takano, Miho Ibi, Natsumi Ushijima, Eijiro Miyako, Masako Yudasaka, Yukari Maeda, Daisuke Konishi, Kiwamu Sakaguchi, Atsuro Yokoyama
{"title":"Carbon nanohorn coating on titanium promotes M2 macrophage polarization.","authors":"Sadahito Kimura, Eri Hirata, Yuta Takano, Miho Ibi, Natsumi Ushijima, Eijiro Miyako, Masako Yudasaka, Yukari Maeda, Daisuke Konishi, Kiwamu Sakaguchi, Atsuro Yokoyama","doi":"10.4012/dmj.2025-028","DOIUrl":"10.4012/dmj.2025-028","url":null,"abstract":"<p><p>This study investigated the effects of carbon nanohorns (CNHs) coated on titanium surfaces on macrophage responses. The CNHs were electrodeposited on titanium discs to create a uniform coating with a thickness of 0.2-0.3 µm. Analysis of macrophages cultured on CNH-modified titanium (CNH/Ti) revealed decreased production of pro-inflammatory cytokines (TNFα and IL6) and increased IL10 gene expression compared to unmodified titanium. Immunofluorescence analysis showed higher expression of the M2 marker CD206 and lower expression of the M1 marker CD86 on the CNH/Ti surfaces. Gene expression analysis indicated downregulation of genes involved in DNA transcription, repair, and replication, correlating with controlled cell proliferation on CNH/Ti. These findings demonstrate that CNH modification on titanium surfaces influences macrophage cytokine production and phenotype marker expression, suggesting its potential application in dental implant development.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"564-571"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145074501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of desensitizing and/or anti-erosive toothpastes combined with mouthrinses on enamel structure and dental pulp fibroblasts viability. 脱敏和/或抗腐蚀牙膏联合漱口水对牙釉质结构和牙髓成纤维细胞活力的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-09-05 DOI: 10.4012/dmj.2024-380
Géssica Lopes, Thainá Pinto, Paula Moreira DE Carvalho, Giovanna Sarra, Kelson Faial, Márcia Marques, Rafael Lima, Roberta D'Almeida-Couto
{"title":"Effects of desensitizing and/or anti-erosive toothpastes combined with mouthrinses on enamel structure and dental pulp fibroblasts viability.","authors":"Géssica Lopes, Thainá Pinto, Paula Moreira DE Carvalho, Giovanna Sarra, Kelson Faial, Márcia Marques, Rafael Lima, Roberta D'Almeida-Couto","doi":"10.4012/dmj.2024-380","DOIUrl":"10.4012/dmj.2024-380","url":null,"abstract":"<p><p>This study evaluated the chemical profile of toothpastes (TPs) and mouthrinses (MRs) and their effects on tooth enamel ultrastructure, and the viability of human dental pulp fibroblasts (hDPF). Four TPs and MRs containing different remineralizing agents (arginine, potassium nitrate, pro arginine, and stannous chloride) were analyzed for pH, titratable acidity (TA), and ion concentrations (Ca<sup>+2</sup>, K<sup>+</sup>, Na<sup>+2</sup>). Enamel ultrastructure was evaluated using Fourier-transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM). Cell viability was assessed after treatments exposure. TPs and MRs had pH values ranging from 4.43 to 8.87, with SnCl<sub>2</sub>-MR showing the highest TA. Alterations in enamel surface were observed with decrease of Amide I, carbonate and potassium peaks. Combinations of TP+MR reduced calcium concentration. Cell viability was reduced as response to all TP+MR combinations, except to ProArg-MR. These findings suggest that combining TPs and MRs may not enhance their effectiveness and could harm enamel and dental pulp cells.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"487-496"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145014047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research trends and mapping knowledge for enamel matrix derivatives in dentistry: A bibliometric and scientometric analysis. 牙釉质基质衍生物的研究趋势和测绘知识：文献计量学和科学计量学分析。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-08-05 DOI: 10.4012/dmj.2025-058
Nuray Ercan
{"title":"Research trends and mapping knowledge for enamel matrix derivatives in dentistry: A bibliometric and scientometric analysis.","authors":"Nuray Ercan","doi":"10.4012/dmj.2025-058","DOIUrl":"10.4012/dmj.2025-058","url":null,"abstract":"<p><p>This bibliometric analysis is aimed at identifying and analyzing the articles on the dental applications of enamel matrix derivatives (EMDs). Data were obtained from the Web of Science and analyzed using the Bibliometrix program. Publications indexed in SCI-Expanded and ESCI under 'Dentistry, Oral Surgery, and Medicine' were included, while non-English and non-article/review types were excluded. A total of 854 articles were reviewed, focusing on: article performance, word analysis, co-citation, and thematic analysis. Data analysis showed a growing number of publications in this field over time. Sculean A emerged as the leading researcher, while the Journal of Clinical Periodontology was the most influential journal. Recent research trends primarily focused on periodontal regeneration. Finally, thematic analysis revealed two motor themes, four niche themes, two emerging/declining themes, and three basic theme clusters. This bibliometric analysis highlights the increasing interest and the emergence of new research trends in the field of EMDs in dentistry.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"507-517"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of chitosan as a novel antimicrobial dental material -Effects of form, molecular weight, and deacetylation degree on its antimicrobial activity against Candida albicans. 壳聚糖作为新型口腔抗菌材料的应用——形态、分子量和去乙酰化程度对其抗白色念珠菌活性的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-08-05 DOI: 10.4012/dmj.2024-372
Kouki Miura, Airi Matsumoto, Yuichi Oogai, Masanobu Nakata, Yoshihiro Nishitani
{"title":"Application of chitosan as a novel antimicrobial dental material -Effects of form, molecular weight, and deacetylation degree on its antimicrobial activity against Candida albicans.","authors":"Kouki Miura, Airi Matsumoto, Yuichi Oogai, Masanobu Nakata, Yoshihiro Nishitani","doi":"10.4012/dmj.2024-372","DOIUrl":"10.4012/dmj.2024-372","url":null,"abstract":"<p><p>Oral candidiasis is a significant health concern, especially for elderly individuals. The present study examined chitosan as a potential antimicrobial dental material for Candida albicans treatment. Four types of chitosan products purified from Chionoecetes opilio and Decapodiformes, with varying weight average molecular weight and degree of deacetylation (DAC) were used. Antimicrobial activity was assessed with fungal viability assays, culture turbidity measurements, and live/dead cell staining, while mechanism of action was determined by examining extracellular adenosine triphosphate (ATP) level, reactive oxygen species (ROS) production, and gene expression changes. All examined products exhibited antimicrobial activity, with Decapodiformes-derived chitosan showing better efficacy. Greater molecular weight was correlated with immediate effects and higher DAC with sustained activity. Chitosan treatment increased extracellular ATP and ROS levels, and suppression of genes involved in mitochondrial biosynthesis and drug resistance. These findings suggest potential use of chitosan as an antimicrobial agent in dental materials for oral candidiasis prevention and treatment.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"497-506"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Water and solute permeability of membranes used in guided bone regeneration-An in vitro study. 引导骨再生中膜的水和溶质渗透性的体外研究。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-09-12 DOI: 10.4012/dmj.2024-371
Radu Ioan Neacsu, Horia Nitu, Anca Sipos, Lucian Barbu-Tudoran, Adrian Nicoara, Amelia Bucur, Alina Ormenisan
{"title":"Water and solute permeability of membranes used in guided bone regeneration-An in vitro study.","authors":"Radu Ioan Neacsu, Horia Nitu, Anca Sipos, Lucian Barbu-Tudoran, Adrian Nicoara, Amelia Bucur, Alina Ormenisan","doi":"10.4012/dmj.2024-371","DOIUrl":"10.4012/dmj.2024-371","url":null,"abstract":"<p><p>Nutrients diffusion through barrier membranes used in guided bone regeneration is much theorized but few data are available so far. In this study, direct measurement of the water and solute permeability coefficients of five commercial barrier membranes was performed and the results were correlated with scanning electron microscopy findings. First the hydraulic permeability was addressed in short (3 h) and extended periods (3 weeks) assays, then the membranes were further investigated for diffusion of selected solutes (glucose and NaCl). The collagen membrane had the highest initial water permeability, 10 times greater than the polylactide one, and 500 times greater than the expanded-PTFE one, all of which decreased significantly over the 3-weeks test period, whereas dense-PTFE membranes were both found impermeable, the results being positively correlated with solute permeability coefficients and convergent with the SEM findings.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"535-546"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145074564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of postoperative intracoronal bleaching on the microtensile bond strength at the composite-dentin interface. 术后冠内漂白对复合牙本质界面微拉伸结合强度的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-08-27 DOI: 10.4012/dmj.2025-046
Gizem Ayan, Tuğba Misilli, Mehmet Buldur, Ayşe Nur Doğan
{"title":"The impact of postoperative intracoronal bleaching on the microtensile bond strength at the composite-dentin interface.","authors":"Gizem Ayan, Tuğba Misilli, Mehmet Buldur, Ayşe Nur Doğan","doi":"10.4012/dmj.2025-046","DOIUrl":"10.4012/dmj.2025-046","url":null,"abstract":"<p><p>The study evaluated the effects of postoperative bleaching with HP and CP on microtensile bond strength (μTBS) and nanoleakage of composite restorations using total-/self-etch protocols. Sixty incisors with Black V cavities were restored using a multimode adhesive in total-/self-etch mode and resin composite. Samples were divided into five groups: control, CP×2, CP×5, HP×2, HP×5. After bleaching, 1×1×8 mm composite blocks (n=10) were tested for μTBS, and failure types were assessed. Two samples per group were analyzed for nanoleakage via scanning electron microscope (SEM). Two-way analysis of variance, Bonferroni correction, and stepwise linear regression were applied. CP×5 and HP×5 groups exhibited significantly reduced μTBS compared to control, and the self-etch protocol resulted in lower values regardless of bleaching method. Regression analysis confirmed significant effects of adhesive (total-etch) and bleaching (CP×5, HP×5). A significant relationship was found between failure modes and bleaching methods for each adhesive protocol, with adhesive failures being the most frequent. SEM revealed nanoleakage in all groups.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"589-598"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144946149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of air abrasion on the bonding performance of universal adhesives to bovine dentin. 空气磨损对通用胶粘剂与牛牙本质粘合性能的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-09-30 Epub Date: 2025-09-05 DOI: 10.4012/dmj.2025-001
Yoshiharu Kawai, Rei Muto, Tosihiki Takamizawa, Ryo Ishii, Ryota Aoki, Shunichi Suda, Yuta Kasahara, Soshi Suzuki, Masashi Miyazaki
{"title":"Influence of air abrasion on the bonding performance of universal adhesives to bovine dentin.","authors":"Yoshiharu Kawai, Rei Muto, Tosihiki Takamizawa, Ryo Ishii, Ryota Aoki, Shunichi Suda, Yuta Kasahara, Soshi Suzuki, Masashi Miyazaki","doi":"10.4012/dmj.2025-001","DOIUrl":"10.4012/dmj.2025-001","url":null,"abstract":"<p><p>This study aimed to determine the influence of air abrasion on the shear bond strength (SBS) of universal adhesives when using different abrasive powders. The AquaCare Twin served as the injection device. The prepared bovine dentin specimens were air- abraded with alumina particles or bioactive glass before applying the universal adhesive (All Bond Universal, Clearfil Universal Bond Quick ER, or Scotchbond Universal Plus Adhesive). The resin composite-bonded specimens were stored in distilled water at 37°C for 24 h before measuring the SBS. The roughness and free energy of the adherent surfaces were measured, followed by scanning electron microscopy (SEM) and SEM/Energy dispersive X-ray analyses. Dentin pre-treatment and the adhesives used significantly affected the SBS values (p<0.001). Significant interactions were observed between pre-treatment conditions and the adhesive system (p<0.001). The bond strengths of universal adhesive depended on the surface properties of the dentin and the powder used.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"579-588"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145014060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytotoxicity of surface pre-reacted glass-ionomer filler containing composite resin in human periodontal ligament cells. 含复合树脂表面预反应玻璃离聚体填料对人牙周韧带细胞的细胞毒性。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-07-31 Epub Date: 2025-07-05 DOI: 10.4012/dmj.2025-003
Yuriko Mukunoki, Shengjian Jin, Naofumi Tamaki, Yasusei Kudo, Keiichi Hosaka
{"title":"Cytotoxicity of surface pre-reacted glass-ionomer filler containing composite resin in human periodontal ligament cells.","authors":"Yuriko Mukunoki, Shengjian Jin, Naofumi Tamaki, Yasusei Kudo, Keiichi Hosaka","doi":"10.4012/dmj.2025-003","DOIUrl":"10.4012/dmj.2025-003","url":null,"abstract":"<p><p>This study evaluated the cytotoxicity of various composite resins (CRs) on human periodontal ligament (PDL) cells, focusing on material composition and ion release. Eight CRs of three sizes were tested: Large (6.5 mm diameter, 1.5 mm thickness), Medium (2.0 mm diameter, 1.5 mm thickness), and Small (1.5 mm diameter, 0.5 mm thickness). Cytotoxicity was assessed by cell counting on immortalized and primary PDL cell lines. CRs containing Surface pre-reacted glass ionomer filler showed significant size-dependent cytotoxicity, with larger specimens exhibiting higher ion release of BO<sub>3</sub><sup>3-</sup>, Sr<sup>2+</sup>, SiO<sub>3</sub><sup>2-</sup>, and F<sup>-</sup>, which correlated with adverse effects. Smaller specimens with reduced ion release had lower cytotoxicity and sometimes promoted cell proliferation. These results emphasize the role of material composition and ion release in the biocompatibility of CR for subgingival restorations. Optimizing specimen size and controlling ion release could mitigate adverse effects, suggesting further research to balance therapeutic benefits and risks in periodontal tissues.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"456-462"},"PeriodicalIF":1.9,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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