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Effects of vehicles on the physical properties and biocompatibility of premixed calcium silicate cements. 载体对预混合硅酸钙水泥的物理性质和生物相容性的影响。
IF 2.5 4区 医学
Dental materials journal Pub Date : 2024-03-29 Epub Date: 2024-03-05 DOI: 10.4012/dmj.2023-147
Gitae Son, Gyeung Mi Seon, Sang Hoon Choi, Hyeong-Cheol Yang
{"title":"Effects of vehicles on the physical properties and biocompatibility of premixed calcium silicate cements.","authors":"Gitae Son, Gyeung Mi Seon, Sang Hoon Choi, Hyeong-Cheol Yang","doi":"10.4012/dmj.2023-147","DOIUrl":"10.4012/dmj.2023-147","url":null,"abstract":"<p><p>Premixed calcium silicate cements (pCSCs) contain vehicles which endow fluidity and viscosity to CSCs. This study aimed to investigate the effects of three vehicles, namely, polyethylene glycol (PEG), propylene glycol (PG), and dimethyl sulfoxide (DMSO), on the physicochemical properties and biocompatibility of pCSCs. The setting time, solubility, expansion rate, and mechanical strength of the pCSCs were evaluated, and the formation of calcium phosphate precipitates was assessed in phosphate-buffered saline (PBS). The effects of pCSC extracts on the osteogenic differentiation of mesenchymal stem cells (MSCs) were investigated. Finally, the tissue compatibility of pCSCs in rat femurs was observed. CSC containing PEG (CSC-PEG) exhibited higher solubility and setting time, and CSC-DMSO showed the highest expansion rate and mechanical strength. All pCSCs generated calcium phosphate precipitates. The extract of CSC-PG induced the highest expressions of osteogenic markers along with the greatest calcium deposites. When implanted in rat femurs, CSC-PEG was absorbed considerably, whereas CSC-PG remained relatively unaltered inside the femur.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"276-285"},"PeriodicalIF":2.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140049038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scanning electron microscopy observation of dentin bond interfaces in different types of resin luting cements. 扫描电子显微镜观察不同类型树脂胶结剂中的牙本质粘接界面。
IF 2.5 4区 医学
Dental materials journal Pub Date : 2024-03-29 Epub Date: 2024-01-20 DOI: 10.4012/dmj.2023-219
Toshiki Takamizawa, Ryota Aoki, Kana Hayashi, Mone Shoji, Yuta Kasahara, Wayne W Barkmeier, Mark A Latta, Atsushi Kamimoto, Masashi Miyazaki
{"title":"Scanning electron microscopy observation of dentin bond interfaces in different types of resin luting cements.","authors":"Toshiki Takamizawa, Ryota Aoki, Kana Hayashi, Mone Shoji, Yuta Kasahara, Wayne W Barkmeier, Mark A Latta, Atsushi Kamimoto, Masashi Miyazaki","doi":"10.4012/dmj.2023-219","DOIUrl":"10.4012/dmj.2023-219","url":null,"abstract":"<p><p>This study aimed to observe and compare the resin luting cement (RLC)/dentin interfaces of different types of RLC systems with scanning electron microscopy (SEM). This study evaluated six self-adhesive resin luting cement systems (SARLCs), four systems combining a SARLC with a tooth primer (SARLCPs), and six conventional resin luting cement systems (CVRLCs). Cured resin composite rods were bonded to bovine dentin using RLCs in different etching modes. The morphological features at the interfaces were observed using SEM. Although all RLCs in etch-&-rinse (ER) mode showed a clear hybrid layer, most SARLCs had a thinner and more porous hybrid layer than the SARLCPs and CVRLCs. All SARLCPs with primer and CVRLCs showed a thin high-density layer below the primer layer in both etching modes. CVRLCs and SARLCPs with primer treatment systems may be more versatile and reliable when compared to simplified RLC systems.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"179-190"},"PeriodicalIF":2.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139511871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploration of reference genes for the development of a diagnostic kit on vascular aging in human saliva. 为开发人类唾液血管老化诊断试剂盒探索参考基因。
IF 2.5 4区 医学
Dental materials journal Pub Date : 2024-03-29 Epub Date: 2024-01-20 DOI: 10.4012/dmj.2023-242
Shinsuke Miyoshi, Akiyo Kawamoto, Yuichi Ninomiya, Yoshihiro Hamada, Hideo Shimizu, Yoshitomo Honda, Kazuya Takahashi
{"title":"Exploration of reference genes for the development of a diagnostic kit on vascular aging in human saliva.","authors":"Shinsuke Miyoshi, Akiyo Kawamoto, Yuichi Ninomiya, Yoshihiro Hamada, Hideo Shimizu, Yoshitomo Honda, Kazuya Takahashi","doi":"10.4012/dmj.2023-242","DOIUrl":"10.4012/dmj.2023-242","url":null,"abstract":"<p><p>Identifying reliable biomarkers in saliva can be a promising approach to developing a rapid diagnostic kit for detecting vascular aging. This study investigated the most suitable reference gene for polymerase chain reaction (PCR) in saliva that is not affected by vascular aging variables. Whole saliva samples were collected to assess the expression of reference genes: actin beta (ACTB), 18S ribosomal RNA (18S rRNA), beta-2-microglobulin, and glyceraldehyde-3-phosphate dehydrogenase (GAPDH). The most abundantly expressed gene was 18S rRNA, and the least expressed gene was GAPDH. Four genes were ranked according to their relative stability, as determined by mathematical algorithms, indicating that ACTB and 18S rRNA were stably expressed as reference genes. 18S rRNA was identified as the most promising reference gene for detecting systemic diseases using saliva from patients with vascular aging in these limited experimental conditions.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"172-178"},"PeriodicalIF":2.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139511837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of adhesive components in experimental fluoride varnish on fluoride release within 30 days in vitro study. 实验性氟化物涂膜中的粘合剂成分对 30 天内氟化物释放的影响体外研究。
IF 2.5 4区 医学
Dental materials journal Pub Date : 2024-03-29 Epub Date: 2024-02-22 DOI: 10.4012/dmj.2023-299
Soo-Auk Park, Julee Son, Ah-Jin Kim, Seunghan Oh, Ji-Myung Bae
{"title":"Effect of adhesive components in experimental fluoride varnish on fluoride release within 30 days in vitro study.","authors":"Soo-Auk Park, Julee Son, Ah-Jin Kim, Seunghan Oh, Ji-Myung Bae","doi":"10.4012/dmj.2023-299","DOIUrl":"10.4012/dmj.2023-299","url":null,"abstract":"<p><p>We aimed to determine whether adhesive components could increase the release time of effective fluoride concentration from an experimental fluoride varnish applied to bovine teeth. An experimental fluoride varnish containing 5% sodium fluoride (EX1) was prepared and combined with 35% hydroxyethyl methacrylate (HEMA) (EX2), 5% glutaraldehyde (EX3), or 35% HEMA/5% glutaraldehyde mixture (EX4). Two commercially available fluoride varnishes were used for comparison. Each group was applied to bovine incisors, and the fluoride release and pH were monitored for 30 days. Cell viability analysis, scanning electron microscopy, and energy-dispersive spectroscopy were performed. EX4 released the highest and most effective concentration of fluoride for the longest period and reached neutral pH at the earliest; the release was maintained for up to 30 days without cytotoxicity. In conclusion, EX4 is considered to be the most effective varnish to prevent dental caries.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"320-327"},"PeriodicalIF":2.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139930466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in enamel hardness, wear resistance, surface texture, and surface crystal structure with glass ionomer cement containing BioUnion fillers. 含有 BioUnion 填充物的玻璃离聚物水泥对珐琅质硬度、耐磨性、表面纹理和表面晶体结构的影响。
IF 2.5 4区 医学
Dental materials journal Pub Date : 2024-03-29 Epub Date: 2024-02-22 DOI: 10.4012/dmj.2023-180
Misuzu Sagawa, Yasuhiro Namura, Yasuki Uchida, Wakako Miyama, Shirabe Nishimura, Toshihiro Yoneyama, Toshiki Takamizawa, Mitsuru Motoyoshi
{"title":"Changes in enamel hardness, wear resistance, surface texture, and surface crystal structure with glass ionomer cement containing BioUnion fillers.","authors":"Misuzu Sagawa, Yasuhiro Namura, Yasuki Uchida, Wakako Miyama, Shirabe Nishimura, Toshihiro Yoneyama, Toshiki Takamizawa, Mitsuru Motoyoshi","doi":"10.4012/dmj.2023-180","DOIUrl":"10.4012/dmj.2023-180","url":null,"abstract":"<p><p>This study investigated the potential of BioUnion filler containing glass ionomer cement (GIC) to enhance the properties of enamel surrounding restorations, with a specific focus on the effect on hardness. The hardness of the bovine enamel immersed in the cement was measured using Vickers hardness numbers. Following sliding and impact wear simulations, the enamel facets were examined using confocal-laser-scanning microscopy and scanning-electron microscopy. Surface properties were further analyzed using energy-dispersive X-ray spectroscopy and X-ray diffraction (XRD). A significant increase in Vickers hardness numbers was observed in the BioUnion filler GIC after 2 days. Furthermore, the mean depth of enamel facets treated with BioUnion filler GIC was significantly less than that of untreated facets. Characteristic XRD peaks indicating the presence of hydroxyapatite were also observed. Our findings imply that GIC with BioUnion fillers enhances the mechanical properties of the tooth surface adjacent to the cement.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"247-254"},"PeriodicalIF":2.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139930465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biocompatibility of dental implants coated with hydroxyapatite using pulsed Er:YAG laser deposition. 使用脉冲 Er:YAG 激光沉积羟基磷灰石涂层的牙科植入物的生物相容性。
IF 2.5 4区 医学
Dental materials journal Pub Date : 2024-03-29 Epub Date: 2024-02-29 DOI: 10.4012/dmj.2023-235
Yuri Kuki, Kenzo Morinaga, Naoya Uemura, Tomoharu Okamura, Shigeki Hontsu, Yoshiya Hashimoto, Shunsuke Baba
{"title":"Biocompatibility of dental implants coated with hydroxyapatite using pulsed Er:YAG laser deposition.","authors":"Yuri Kuki, Kenzo Morinaga, Naoya Uemura, Tomoharu Okamura, Shigeki Hontsu, Yoshiya Hashimoto, Shunsuke Baba","doi":"10.4012/dmj.2023-235","DOIUrl":"10.4012/dmj.2023-235","url":null,"abstract":"<p><p>We aimed to improve the biocompatibility and osteoinductive potential of Ti implants using a simulated intraoral hydroxyapatite (HAp) coating. We devised a novel surface treatment for aggressive induction of osteoblast adhesion and bone regeneration on the implant surface. A thin α-tricalcium phosphate (α-TCP) film was deposited on the implant surface using a pulsed Er:YAG laser. The coating was converted to HAp through artificial saliva immersion, which was confirmed using scanning electron microscopy (SEM) and X-ray diffraction (XRD). SEM showed needle-like HAp crystals on the Ti disks and sandblasted implant surfaces after immersion in artificial saliva for 96 h. Microcomputed tomography and histological evaluation 4 and 8 weeks after implantation into beagle dog mandibles showed that the HAp-coated implant was biocompatible and exhibited superior osteoinduction compared to that of sandblasted implants. Coating the implant surface with HAp using an Er:YAG laser has potential as a new method of the implant-surface debridement.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"269-275"},"PeriodicalIF":2.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioactivity of human dental pulp-derived stem cells with boron-controlled S-PRG filler eluate by anion exchange. 通过阴离子交换法，利用硼控制的 S-PRG 填充物洗脱液提高人牙髓干细胞的生物活性。
IF 2.5 4区 医学
Dental materials journal Pub Date : 2024-03-29 Epub Date: 2024-03-01 DOI: 10.4012/dmj.2023-145
Yusuke Tatsumi, Harumi Kawaki, Kohei Shintani, Kyohei Ueno, Masato Hotta, Nobuo Kondoh, Michael F Burrow, Toru Nikaido
{"title":"Bioactivity of human dental pulp-derived stem cells with boron-controlled S-PRG filler eluate by anion exchange.","authors":"Yusuke Tatsumi, Harumi Kawaki, Kohei Shintani, Kyohei Ueno, Masato Hotta, Nobuo Kondoh, Michael F Burrow, Toru Nikaido","doi":"10.4012/dmj.2023-145","DOIUrl":"10.4012/dmj.2023-145","url":null,"abstract":"<p><p>Surface pre-reacted glass-ionomer (S-PRG) filler is a bioactive glass filler capable of releasing various ions. A culture medium to which was added an S-PRG filler eluate rich in boron was reported to enhance alkaline phosphatase (ALP) activity in human dental pulp-derived stem cells (hDPSC). To clarify the role of boron eluted from S-PRG fillers, the modified S-PRG filler eluate with different boron concentrations was prepared by using an anion exchange material. Therefore, elemental mapping analysis of anion exchange material, adsorption ratio, hDPSCs proliferation and ALP activity were evaluated. For statistical analysis, Kruskal-Wallis test was used, with statistical significance determined at p<0.05. ALP activity enhancement was not observed in hDPSC cultured in the medium that contained the S-PRG filler eluate from which boron had been removed. The result suggested the possibility that an S-PRG filler eluate with controlled boron release could be useful for the development of novel dental materials.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"255-262"},"PeriodicalIF":2.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative bonding performance of coronal dentin disks and CAD/CAM resin composite disks for biological restoration: The impact of resin-coating technique. 用于生物修复的冠状牙本质盘和 CAD/CAM 树脂复合材料盘的粘接性能比较：树脂涂层技术的影响
IF 2.5 4区 医学
Dental materials journal Pub Date : 2024-03-29 Epub Date: 2024-03-05 DOI: 10.4012/dmj.2023-229
Hiroki Ishihara, Kazuhide Yonekura, Masaomi Ikeda, Go Inoue, Masatoshi Nakajima, Yasushi Shimada, Keiichi Hosaka
{"title":"Comparative bonding performance of coronal dentin disks and CAD/CAM resin composite disks for biological restoration: The impact of resin-coating technique.","authors":"Hiroki Ishihara, Kazuhide Yonekura, Masaomi Ikeda, Go Inoue, Masatoshi Nakajima, Yasushi Shimada, Keiichi Hosaka","doi":"10.4012/dmj.2023-229","DOIUrl":"10.4012/dmj.2023-229","url":null,"abstract":"<p><p>This study evaluated the bonding performance of coronal dentin disks, designed for biological restoration, and CAD/CAM resin composite disks when bonded to flat dentin surfaces using dual-cure resin cements, with and without a resin-coating (RC) technique. Three distinct groups were established within the non-RC group, each using one of the two types of resin cements in a self-adhesive mode: one-step self-etch adhesive (1-SEA) without light-cure, 1-SEA with light-cure, and a separate group using an alternate cement. Within the RC group, a subgroup was established for each cement. The microtensile bond strength (μTBS) of the disk-dentin beam was tested after 0 and 10,000 thermocycles in a 5°C/55°C. No significant μTBS difference was observed among the non-RC groups. However, when using RC, the μTBSs of coronal dentin disks significantly exceeded those of CAD/CAM resin composite disks. Thermocycle aging did not affect μTBS in any of the bonding methods, except in self-adhesive mode.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"303-311"},"PeriodicalIF":2.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140049037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of low-temperature degradation and sintering protocols on the color of monolithic zirconia crowns with different yttria contents. 低温降解和烧结方案对不同钇含量的整体氧化锆冠颜色的影响。
IF 2.5 4区 医学
Dental materials journal Pub Date : 2024-03-29 Epub Date: 2024-01-31 DOI: 10.4012/dmj.2023-194
Shoko Miura, Akikazu Shinya, Hiroyasu Koizumi, Pekka Vallittu, Lippo Lassila, Masanori Fujisawa
{"title":"Effect of low-temperature degradation and sintering protocols on the color of monolithic zirconia crowns with different yttria contents.","authors":"Shoko Miura, Akikazu Shinya, Hiroyasu Koizumi, Pekka Vallittu, Lippo Lassila, Masanori Fujisawa","doi":"10.4012/dmj.2023-194","DOIUrl":"10.4012/dmj.2023-194","url":null,"abstract":"<p><p>This study investigated the effects of low-temperature degradation (LTD) on the L*, a*, and b* values of highly translucent zirconia crowns. Four types of zirconia disks with different yttria contents (IPS e.max ZirCAD LT, IPS e.max ZirCAD MT, IPS e.max ZirCAD MT Multi, IPS e.max ZirCAD Prime, Ivoclar) and two shades (A2 and BL) were used. A crown was manufactured using four types of zirconia and LTD treated. Color measurements were performed, and the color difference (ΔE<sub>00</sub>) before and after LTD was calculated. The microstructure was determined through X-ray fluorescence and X-ray diffractometry. Highly translucent zirconia crowns showed greater changes in the a* and b* values than in the L* value after LTD, regardless of the shade. The Multi2 crowns exhibited a discernible color change due to the LTD treatment. The X-ray fluorescence results did not reveal any apparent change in the microstructure between sintering programs for all zirconia specimens.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"164-171"},"PeriodicalIF":2.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139722039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of wear and marginal fitness of 3D-printed deciduous molar crowns: An in vitro study. 3D 打印落叶磨牙牙冠的磨损和边缘适应性比较：体外研究
IF 2.5 4区 医学
Dental materials journal Pub Date : 2024-03-29 Epub Date: 2024-02-29 DOI: 10.4012/dmj.2022-143
Bin Lei, Huacui Xiong, Ke Chen
{"title":"Comparison of wear and marginal fitness of 3D-printed deciduous molar crowns: An in vitro study.","authors":"Bin Lei, Huacui Xiong, Ke Chen","doi":"10.4012/dmj.2022-143","DOIUrl":"10.4012/dmj.2022-143","url":null,"abstract":"<p><p>This study aimed to evaluate the wear resistance of primary tooth enamel and 3 kinds of 3D printing materials and to compare the marginal fitness and internal suitability of prefabricated all-ceramic crowns, computer-aided design/manufacturing (CAD/CAM) all-ceramic crowns, and three 3D-printed deciduous molar crowns. Multifunctional friction wear testing machine was used to image the wear surface of the sample and calculate the maximum wear depth and volume loss value of each sample. The internal fit evaluation used the silicon replica method, The four points were measured using scanning electron microscopy (SEM). The obtained data were statistically analyzed using ANOVA and Tukey HSD-test with a fully randomized design (p<0.05). The results showed the wear resistance of E-Dent400 was better than that of PEEK and three different 3D printed materials have good wear resistance compared with the primary tooth enamel. The measured values at M1 and M4 of E-Dent400 were both the smallest.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"227-234"},"PeriodicalIF":2.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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