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Development of a new self-cleaning denture base material using titanium apatite. 磷灰石钛基托自洁材料的研制。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-05-10 DOI: 10.4012/dmj.2024-100
Satoshi Komasa, Yuichiro Tashiro, Akiko Miyake, Takumi Matsumoto, Xin Wang, Mariko Nakai, Hideaki Sato, Yoshiya Hashimoto
{"title":"Development of a new self-cleaning denture base material using titanium apatite.","authors":"Satoshi Komasa, Yuichiro Tashiro, Akiko Miyake, Takumi Matsumoto, Xin Wang, Mariko Nakai, Hideaki Sato, Yoshiya Hashimoto","doi":"10.4012/dmj.2024-100","DOIUrl":"https://doi.org/10.4012/dmj.2024-100","url":null,"abstract":"<p><p>Appropriate self-cleaning denture base materials should be developed to prevent denture stomatitis and aspiration pneumonia in older patients and improve their quality of life. We aimed to develop a new denture base material by introducing titanium apatite, an antibacterial material, into a conventional denture base resin. We added titanium apatite (TiHA) during polymerization of methyl methacrylate (MMA) to PMMA. The control group was composed of 0% TiHA, and the experimental groups were composed of 3%, 6%, and 9% TiHA. Surface analysis revealed the distribution of the TiHA crystals on the PMMA surface in the experimental group. We found that the higher the TiHA concentration, the more bacterial growth was suppressed. No significant reduction in the compressive strength was observed. In conclusion, TiHA is a useful material in denture base resin since it is resistant to surface contamination and bacterial adhesion.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of 1,500 ppm NaF solution at different pH levels on the mechanical and physicochemical properties of CAD-CAM materials. 不同pH值下1500ppm NaF溶液对CAD-CAM材料力学和物理化学性能的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-04-29 DOI: 10.4012/dmj.2024-339
Misaki Matsuo, Yuya Komagata, Yuki Nagamatsu, Inho Soh, Hiroshi Ikeda
{"title":"Impact of 1,500 ppm NaF solution at different pH levels on the mechanical and physicochemical properties of CAD-CAM materials.","authors":"Misaki Matsuo, Yuya Komagata, Yuki Nagamatsu, Inho Soh, Hiroshi Ikeda","doi":"10.4012/dmj.2024-339","DOIUrl":"https://doi.org/10.4012/dmj.2024-339","url":null,"abstract":"<p><p>Commercial toothpaste contains 1,500 ppm NaF to prevent caries; however, the effect of NaF on tooth restorative materials is not fully understood. This study investigated the impact of a 1,500 ppm NaF solution at different pH levels on the mechanical and physicochemical properties of CAD-CAM materials. Aqueous 1,500 ppm NaF solutions were prepared at pH levels 3, 5, and 7. Four CAD-CAM blocks -lithium disilicate glass, feldspathic porcelain, polymer-infiltrated ceramic network, and resin composite- were immersed in the solutions at 37°C for 10 days. Samples were evaluated for surface roughness, flexural modulus, strength, Vickers hardness, and water sorption/solubility. Results indicated that NaF solutions dissolved silica components, increasing surface roughness and water solubility and reducing hardness, especially at lower pH levels. Flexural properties remained mostly unchanged. These findings suggest that acidic NaF solutions more strongly degrade the surface properties of CAD-CAM materials.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mineral induction and sealing abilities of proprietary bioceramic endodontic sealers. 专有生物陶瓷牙髓封闭器的矿物诱导和封闭能力。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-04-29 DOI: 10.4012/dmj.2024-275
Hefei Li, Haruaki Kitagawa, Yo-Shiuan Fan, Hirohiko Sakai, Ranna Kitagawa, Jun-Ichi Sasaki, Satoshi Yamaguchi, Satoshi Imazato
{"title":"Mineral induction and sealing abilities of proprietary bioceramic endodontic sealers.","authors":"Hefei Li, Haruaki Kitagawa, Yo-Shiuan Fan, Hirohiko Sakai, Ranna Kitagawa, Jun-Ichi Sasaki, Satoshi Yamaguchi, Satoshi Imazato","doi":"10.4012/dmj.2024-275","DOIUrl":"https://doi.org/10.4012/dmj.2024-275","url":null,"abstract":"<p><p>Mineral trioxide aggregate (MTA) cement has excellent properties, such as biocompatibility and mineral induction ability for various dental procedures. To provide these favorable properties, MTA-based sealers, such as MTA Fillapex (MF), Bio-C Sealer (BC), NeoSEALER Flo (NSF), and NeoMTA 2 (NM2), have been developed and introduced into the market. Additionally, an endodontic sealer containing bioactive glass with mineral induction ability was introduced as the Canal Sealer BG (CS-BG). In this study, we evaluated the mineral induction and sealing ability of five bioceramic-based sealers. The results indicated that NSF, NM2, BC, and CS-BG had superior mineral induction capacities compared with MF. Although NSF, NM2, BC, and CS-BG exhibited comparable sealing performances, NSF had a statistically superior sealing capability compared to MF. According to these findings, bioceramic sealers other than MF containing resin components have excellent mineral induction capacity, making them effective for root canal sealing in clinical applications.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of different acid etching protocols on the enhanced osteogenic potential of titanium surfaces: An in vitro study. 不同酸蚀方案对增强钛表面成骨潜能的影响：一项体外研究。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-04-29 DOI: 10.4012/dmj.2024-115
Ting Yang, Wenjie Hu, Kwok-Hung Chung, Fuhua Yang, Hua Yang
{"title":"Effects of different acid etching protocols on the enhanced osteogenic potential of titanium surfaces: An in vitro study.","authors":"Ting Yang, Wenjie Hu, Kwok-Hung Chung, Fuhua Yang, Hua Yang","doi":"10.4012/dmj.2024-115","DOIUrl":"https://doi.org/10.4012/dmj.2024-115","url":null,"abstract":"<p><p>Sandblasted with large grits and acid-etched (SLA) surface topography has been a common method of implant surface modification to promote bone-implant integration in titanium-based dental implant manufacturing. However, the acid etching protocols used are various. The aim of this investigation was to validate the effect of different acid-etched treatments of sandblasted titanium surfaces on enhancing osteogenic potential. Five different titanium surface groups were prepared and tested including: i) smooth (Control), ii) sandblasted (SL), iii) sandblasted and acid-etched with H<sub>2</sub>SO<sub>4</sub>/HCl mixed solution (SLA/SOCl), iv) sandblasted and acid-etched with H<sub>2</sub>SO<sub>4</sub> solution (SLA/SO), and v) sandblasted and acid-etched with HF solution (SLA/HF). The surface characterization, protein adsorption, and cell behavior were examined to determine the osteogenic potential. Compared with the control group, other surface treated groups showed rougher surface, better wettability, more protein absorption, and cell viability, especially in the SLA/SOCl surface group. The results indicated that SLA surfaces prepared with H<sub>2</sub>SO<sub>4</sub>/HCl mixed acid solution provided significant potential to promote osteogenesis.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of adding poloxamer, collagen, and citric acid on mechanical strength, injectability, shape stability, and biocompatibility of mechanochemically modified beta-tricalcium phosphate cement using ball milling. 加入波洛沙姆、胶原蛋白和柠檬酸对球磨机械化学改性磷酸三钙水泥的机械强度、注射性、形状稳定性和生物相容性的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-04-29 DOI: 10.4012/dmj.2024-369
Shigeki Hanawa, Kazumitsu Sekine, Yeeun Kim, Shinya Horiuchi, Keiko Miyoshi, Eiji Tanaka, Kenichi Hamada
{"title":"Effects of adding poloxamer, collagen, and citric acid on mechanical strength, injectability, shape stability, and biocompatibility of mechanochemically modified beta-tricalcium phosphate cement using ball milling.","authors":"Shigeki Hanawa, Kazumitsu Sekine, Yeeun Kim, Shinya Horiuchi, Keiko Miyoshi, Eiji Tanaka, Kenichi Hamada","doi":"10.4012/dmj.2024-369","DOIUrl":"https://doi.org/10.4012/dmj.2024-369","url":null,"abstract":"<p><p>This study focuses on enhancing the mechanical properties and biocompatibility of calcium phosphate cement (CPC), a widely used bone replacement material. CPCs are limited by low mechanical strength and susceptibility to washout in body fluids. Four approaches were employed to improve CPC performance: 1. mechanochemical modification of CPC powder by ball milling to produce modified β-tricalcium phosphate (mβ-TCP) for better strength and injectability; 2. incorporation of poloxamer, a reverse thermosensitive gel, to enhance shape stability at body temperature; 3. addition of type I collagen to promote the cell viability and alkaline phosphatase (ALP) activity of osteoblast-like cells; 4. citric acid inclusion to restore compressive strength and injectability compromised by collagen. The resulting high-performance CPC demonstrated a compressive strength of 50.1 MPa, with significant improvements in injectability, shape stability, cell viability, and ALP activity of osteoblast-like cells.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Osteogenic properties of nano-modified structure titanium surfaces with surface pre-reacted glass eluate solution coatings. 表面预反应玻璃洗脱液涂层纳米修饰结构钛表面的成骨性能。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-04-09 DOI: 10.4012/dmj.2024-236
Sifan Yan, Satoshi Komasa, Min Li, Xin Wang, Lin Ma, Yuanyuan Yang, Yurie Taniguchi, Shihoko Inui, Seiji Takao, Toshiyuki Nakatsuka, Joji Okazaki, Yoshiya Hashimoto
{"title":"Osteogenic properties of nano-modified structure titanium surfaces with surface pre-reacted glass eluate solution coatings.","authors":"Sifan Yan, Satoshi Komasa, Min Li, Xin Wang, Lin Ma, Yuanyuan Yang, Yurie Taniguchi, Shihoko Inui, Seiji Takao, Toshiyuki Nakatsuka, Joji Okazaki, Yoshiya Hashimoto","doi":"10.4012/dmj.2024-236","DOIUrl":"https://doi.org/10.4012/dmj.2024-236","url":null,"abstract":"<p><p>Surface pre-reacted glass (S-PRG) fillers, a new type of bioactive molecule, can release various ions (Al<sup>3+</sup>, BO<sub>3</sub><sup>3-</sup>, Na<sup>+</sup>, SiO<sub>3</sub><sup>2-</sup>, Sr<sup>2+</sup>, and F<sup>-</sup>) and exhibit high biocompatibility, good antibacterial properties, low plaque accumulation, and enhanced osteoblast differentiation. An alkali-treated titanium layer with a porous nanonetwork structure (TNS) promotes cell adhesion and produces a stronger osseointegration effect than that of a non-treated titanium layer. In this study, the osseointegration effect of TNS was enhanced by incorporating an S-PRG eluate solution. The efficiencies of TNS coatings with different S-PRG concentrations were determined by performing surface analysis, cell experiments, and animal experiments. The results revealed that the introduction of the S-PRG eluate solution promoted the osteogenic ability of TNS. The combination of these two materials offers a novel approach to the investigation of oral implant materials.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143978734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dentin bonding performance of the new self-adhesive resin composite. 新型自粘树脂复合材料的牙本质粘接性能。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-04-09 DOI: 10.4012/dmj.2024-148
Shojiro Shimizu, Tomohiro Takagaki, Masaomi Ikeda, Michael F Burrow, Toru Nikaido
{"title":"Dentin bonding performance of the new self-adhesive resin composite.","authors":"Shojiro Shimizu, Tomohiro Takagaki, Masaomi Ikeda, Michael F Burrow, Toru Nikaido","doi":"10.4012/dmj.2024-148","DOIUrl":"https://doi.org/10.4012/dmj.2024-148","url":null,"abstract":"<p><p>This study aimed to evaluate the initial bond strength to dentin with a new self-adhesive resin composite containing a hydrophilic amide monomer using a micro tensile bond strength (μTBS) test. Specimens were ground with #600 SiC. Including a Cleafil Universal Bond Quick ER (UBQ) and resin composite, a new self-adhesive resin composite (SA-100R; SAR), and a commercially self-adhesive resin composite (Constic; CON), were tested. Adhesion procedures were conducted according to each manufacturer's instructions. Specimens were stored for 24 h in water at 37ºC, then cut into a 1.0×1.0 mm beams. μTBS tests were conducted at a cross-head speed of 1.0 mm/min. Data were statistically analyzed using one-way ANOVA and Bonferroni correction. SAR exhibited values significantly higher than CON (p<0.05), probably due to the improved dentin diffusion by the amide monomer. SAR exhibited stronger adhesion than the CON, shows a high potential for use in various clinical applications, e.g., home-visit dental care.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of bonding agents on metal-ceramic bond strengths for Co-Cr alloy. 结合剂对Co-Cr合金金属-陶瓷结合强度的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-04-09 DOI: 10.4012/dmj.2024-300
Tomofumi Sawada, Kenta Yamanaka, Akihiko Chiba, Shinji Takemoto
{"title":"Influence of bonding agents on metal-ceramic bond strengths for Co-Cr alloy.","authors":"Tomofumi Sawada, Kenta Yamanaka, Akihiko Chiba, Shinji Takemoto","doi":"10.4012/dmj.2024-300","DOIUrl":"https://doi.org/10.4012/dmj.2024-300","url":null,"abstract":"<p><p>This study investigated the influence of bonding agents on metal-ceramic bond strengths before porcelain veneering for cobalt-chromium alloy. Three ceramic systems: Initial MC (IMC), Hera Ceram (HC), and ZEO CE LIGHT (ZCL) were tested on wrought substructures. The ZCL system was also tested on cast substructures. Three-point bending test was performed, and fractured surfaces were analyzed using electron-probe microanalysis and X-ray diffraction. The bond strengths of all specimens exceeded the requirements of ISO 9693:2019 (>25 MPa). The ZCL bonding agent significantly improved bond strengths for wrought and cast substructures whereas the IMC and HC bonding agents did not. Wrought-ZCL specimens exhibited significantly higher bond strengths than cast-ZCL specimens. In the specimens exhibiting higher bond strength, silicon and titanium, which originated from the bonding agent, were predominantly detected at the debonded metallic surfaces. Consequently, the bonding agent positively affected the bond strength but depended on the ceramic system and substructure type.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Finishing efficiencies of additive-manufactured Co-Cr alloy and Ti alloy clasps. 增材制造钴铬合金和钛合金卡扣的精加工效率。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-04-09 DOI: 10.4012/dmj.2024-356
Nagame Mizokoshi, Toshitsugu Sakurai, Hidemasa Shimpo, Noboru Kawamura, Chikahiro Ohkubo
{"title":"Finishing efficiencies of additive-manufactured Co-Cr alloy and Ti alloy clasps.","authors":"Nagame Mizokoshi, Toshitsugu Sakurai, Hidemasa Shimpo, Noboru Kawamura, Chikahiro Ohkubo","doi":"10.4012/dmj.2024-356","DOIUrl":"https://doi.org/10.4012/dmj.2024-356","url":null,"abstract":"<p><p>Additive-manufactured (AMed) Co-Cr and Ti alloy clasps were made with five surface treatments. Either one of a conventional freehand finishing or barrel finishing as a medium finishing process or one of a freehand, dry electrolytic, or magnetic polishings was selected as the final polishing process. After each surface treatment, the polishing efficiencies of the AMed clasps were evaluated as to surface roughness, fitness accuracy, and retentive forces. By surface treatments without using magnetic polishing, sufficient surface smoothness was observed for both alloys. Under all five treatment conditions, better fitness accuracies and sufficient retentive forces were obtained in all Co-Cr and Ti alloy clasps for clinically acceptable results. A combination of barrel finishing and dry electro-polishing can be recommended as the automatic finishing technology, replacing the freehand polishing process by dental technicians. The findings of this study will significantly reduce the workload of dental technicians.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhanced infiltration of myoblasts into collagen scaffolds loaded with engineered basic fibroblast growth factor. 加载工程碱性成纤维细胞生长因子的成肌细胞向胶原支架的浸润增强。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2025-04-09 DOI: 10.4012/dmj.2024-314
Tamamo Matsuyama, Shiina Pasanen, Fumino Futami, Ayari Kato, Isao Hirata, Souichi Yanamoto, Koichi Kato
{"title":"Enhanced infiltration of myoblasts into collagen scaffolds loaded with engineered basic fibroblast growth factor.","authors":"Tamamo Matsuyama, Shiina Pasanen, Fumino Futami, Ayari Kato, Isao Hirata, Souichi Yanamoto, Koichi Kato","doi":"10.4012/dmj.2024-314","DOIUrl":"https://doi.org/10.4012/dmj.2024-314","url":null,"abstract":"<p><p>Tongue reconstruction after cancer resection often involves the use of free skin flaps. However, this strategy has limitations. To overcome these issues, tissue engineering approaches using basic fibroblast growth factor (bFGF) have been investigated to promote tongue muscle regeneration. In this study, a chimeric protein consisting of bFGF and a collagen-binding peptide (CBP-bFGF) was evaluated for its ability to promote myoblast infiltration into collagen-based scaffolds. Results showed that CBP-bFGF promoted the migration of C2C12 myoblasts and their infiltration into collagen sponges. Based on these observations, we propose that the binding of CBP-bFGF with a collagen sponge provides one of the options for accelerating tongue muscle regeneration.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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