Feng Gao, Gabe Chadwell, Qing Hong, Maria Cuevas-Nunez, Kaveh Adel, Marcela R Carrilho, John C Mitchell
{"title":"Fluoride release and strength change of self-adhesive filling materials after storage in water.","authors":"Feng Gao, Gabe Chadwell, Qing Hong, Maria Cuevas-Nunez, Kaveh Adel, Marcela R Carrilho, John C Mitchell","doi":"10.4012/dmj.2024-217","DOIUrl":"https://doi.org/10.4012/dmj.2024-217","url":null,"abstract":"<p><p>The introduction of self-adhesive filling materials has shown advantage in clinical use due to reduced procedure time. The newly developed self-adhesive Surefil One (SO) was compared to other current self-adhesive materials Vertise Flow (VF) and GC Fuji II LC (FJ). Shear bond strength (SBS) to dentin, flexural strength and water sorption were measured at 24 h and 4 weeks. Fluoride release was measured up to 4 weeks. SO showed intermediate fluoride-release that was higher than VF, but lower than FJ. SO demonstrated lower flexural strength than VF at 24 h but maintained that same strength to 4 weeks. SO had SBS comparable to FJ and VF at 24 h but it decreased at 4 weeks. Caution should be exercised when selecting and using SO, as well as the other two self-adhesive materials. Further studies are necessary to evaluate the efficacy for their clinical use in direct restorations.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surface modification of titanium for wear resistance through solid-phase diffusion of iron.","authors":"Hirofumi Yamaguchi, Masatoshi Takahashi, Yukyo Takada, Nobuhiro Yoda","doi":"10.4012/dmj.2024-340","DOIUrl":"https://doi.org/10.4012/dmj.2024-340","url":null,"abstract":"<p><p>Low-wear resistance is a considerable problem with titanium. Despite the excellent wear resistance of Ti-Fe alloys, they exhibit brittleness, complicating their bulk usage. We developed a surface modification method for Ti involving the solid-phase diffusion of iron onto its surface. We coated iron onto the titanium surface and applied heat to successfully form a Ti-Fe alloy layer only on the outermost surface of titanium. The alloy layer exhibited a gradient structure characterized by a continuous decrease in iron concentration from the surface inward, without forming a distinct interface with the base material. Under various heat treatment conditions, the outermost alloy phase of the diffusion layer, in the β phase, resulted in surfaces with exceptional wear resistance. The improved wear resistance can be attributed to the potential surface structure of the Ti-Fe alloy, which combines hardness and ductility. This titanium-integrated structure, resulting from the gradient composition, reduces the likelihood of delamination.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cytotoxicity of surface pre-reacted glass-ionomer filler containing composite resin in human periodontal ligament cells.","authors":"Yuriko Mukunoki, Shengjian Jin, Naofumi Tamaki, Yasusei Kudo, Keiichi Hosaka","doi":"10.4012/dmj.2025-003","DOIUrl":"https://doi.org/10.4012/dmj.2025-003","url":null,"abstract":"<p><p>This study evaluated the cytotoxicity of various composite resins (CRs) on human periodontal ligament (PDL) cells, focusing on material composition and ion release. Eight CRs of three sizes were tested: Large (6.5 mm diameter, 1.5 mm thickness), Medium (2.0 mm diameter, 1.5 mm thickness), and Small (1.5 mm diameter, 0.5 mm thickness). Cytotoxicity was assessed by cell counting on immortalized and primary PDL cell lines. CRs containing Surface pre-reacted glass ionomer filler showed significant size-dependent cytotoxicity, with larger specimens exhibiting higher ion release of BO<sub>3</sub><sup>3-</sup>, Sr<sup>2+</sup>, SiO<sub>3</sub><sup>2-</sup>, and F<sup>-</sup>, which correlated with adverse effects. Smaller specimens with reduced ion release had lower cytotoxicity and sometimes promoted cell proliferation. These results emphasize the role of material composition and ion release in the biocompatibility of CR for subgingival restorations. Optimizing specimen size and controlling ion release could mitigate adverse effects, suggesting further research to balance therapeutic benefits and risks in periodontal tissues.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Changes of surface characteristics after toothbrush abrasion on light-cured shade-characterizing agents for CAD-CAM composite-resin block.","authors":"Akikazu Shinya, Yoshiki Ishida, Shoko Miura, Masanori Fujisawa, Junichi Honda, Futoshi Komine, Tomoko Ikawa, Takumi Ogawa","doi":"10.4012/dmj.2025-008","DOIUrl":"https://doi.org/10.4012/dmj.2025-008","url":null,"abstract":"<p><p>Light-cured shade-characterizing agents are used for composite materials to mimic natural tooth color. Tooth-brushing abrasion tests were conducted to investigate the durability of the agents. Computer-aided design/computer-aided manufacturing (CAD-CAM) composite-resin blocks were used, and the surface was polished with #2000 SiC paper before the agent application. Four different shade agents were applied to the blocks, treated the surface no/with sandblasting. Tooth-brush abrasion tests were carried out for 20,000 cycles at a frequency of 2 Hz with 2.0 N of brushing force. Surface roughness, gloss, contact angle, and color differences were obtained. The number of repetitions was set to ten. It was found that a significant increase in surface roughness and decreases in gloss and water contact angle by tooth brushing tests were clarified. However, the color change by brushing was not significantly large. The color difference before and after applying agents and surface roughness differed in the shade differences in the agents.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dental resin composites modified with ultralong hydroxyapatite nanowires: Synthesis and analysis.","authors":"Shuhan Yang, Xinhong Yu, Dong Han, TianQi Wang, Qi Xie, WeiLi Xie","doi":"10.4012/dmj.2024-362","DOIUrl":"https://doi.org/10.4012/dmj.2024-362","url":null,"abstract":"<p><p>This study examined the effects of ultra-long hydroxyapatite nanofibers on bisphenol A-glycidyl methacrylate (Bis-GMA)/ urethane dimethacrylate (TEGDMA) dental resin. Experimental composites incorporating 2 wt% to 8 wt% ultra-long hydroxyapatite nanofibers were assessed for their mechanical properties, ion release behavior, and cytotoxicity. The results indicated that the addition of 2 wt% or 4 wt% nanofibers significantly enhanced the mechanical attributes of the composite materials, whereas higher concentrations led to a deterioration in performance. Moreover, these materials demonstrated the release of Ca<sup>2+</sup> and PO<sub>4</sub><sup>3-</sup> ions in both artificial saliva and lactic acid solutions, evidencing satisfactory cytocompatibility. The acquired data were subjected to statistical analysis via analysis of variance (ANOVA), with differences deemed statistically significant at p<0.05. Therefore, ultra-long hydroxyapatite nanofiber composites emerge as a promising innovative option for dental restoration.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of a modified margin design, material, and loading type on the stress distribution of endocrowns: A 3D finite element analysis.","authors":"Kerem Yilmaz, Hakan Aydin, Erdem Özdemir","doi":"10.4012/dmj.2024-316","DOIUrl":"https://doi.org/10.4012/dmj.2024-316","url":null,"abstract":"<p><p>In this innovative study, the ferrule design for endocrowns was compared with a new preparation design with tetra-corner retention grooves at each corner of the access cavity, and the 3D finite element method was used for analysis. Resin nanoceramic (RNC), lithium disilicate glass-ceramic (LDS), polyetheretherketone (PEEK), and polymer-infiltrated ceramic network (PICN) materials were investigated. The new design significantly reduced the stress for LDS and PICN in axial and oblique loadings. On remaining tooth tissues, the tetra-corner retention groove design increased the stress peak for RNC and PEEK compared to the ferrule, while it decreased the stress for LDS and PICN under both forces. It was concluded that the new, modified preparation design could be used as an alternative design to the ferrule.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Khairul Anuar Shariff, Alexander Patera Nugraha, Ahmed Hafedh Mohammed Mohammed, Ida Bagus Narmada, I Gusti Aju Wahju Ardani, Nastiti Faradilla Ramadhani, Ratri Maya Sitalaksmi, Wibi Riawan, Helen Susilowati, Suryo Kuncorojakti, Bramasta Nugraha, Guang Hong
{"title":"Osteoinductivity performance dicalcium phosphate dihydrate-coated porous β-tricalcium phosphate granules in adipose-derived mesenchymal stem cells.","authors":"Khairul Anuar Shariff, Alexander Patera Nugraha, Ahmed Hafedh Mohammed Mohammed, Ida Bagus Narmada, I Gusti Aju Wahju Ardani, Nastiti Faradilla Ramadhani, Ratri Maya Sitalaksmi, Wibi Riawan, Helen Susilowati, Suryo Kuncorojakti, Bramasta Nugraha, Guang Hong","doi":"10.4012/dmj.2024-310","DOIUrl":"https://doi.org/10.4012/dmj.2024-310","url":null,"abstract":"<p><p>Elucidate the dicalcium phosphate dihydrate (DCPD)-coated-beta-tricalcium phosphate (β-TCP) porous granules osteoinductivity performance in adipose-derived mesenchymal stem cells (ADMSCs). β-TCP porous was made by adding the sodium chloride (NaCl) powders with the dry powder of DCPD and CaCO<sub>3</sub> in the concentrations 40:60 (by wt%). Then, DCPD layer will be formed on porous β-TCP granules by immersing the granules in an acidic calcium phosphate solution. ADMSCs cultured was used to examine the biocompability of 300-600 µm and 600-1,000 µm DCPD-coated-porous β-TCP by means of microculture tetrazolium technique (MTT assay) and scratch assay. Bone morphogenic protein-2 (BMP-2), Osterix, Runt-related transcription factor-2 (Runx2), Alkaline phosphatase (ALP), Osteopontin, Osteonectin expression were investigated. The DCPD-coated porous β-TCP granules were culture together with ADMSCs is biocompatible. BMP-2, Runx2, Osterix, ALP, Osteopontin, Osteonectin expression in ADMSCs after culture together with DCPD-coated-β-TCP significantly enhanced. DCPD-coated-porous-β-TCP granules have good biocompatibility and high osteoconductivity in ADMSCs.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of octacalcium phosphate on the release behavior of osteogenic factors from PLGA/PCL microspheres.","authors":"Tai Kimura, Ryo Hamai, Masahiro Okada, Kaori Tsuchiya, Kensuke Yamauchi, Osamu Suzuki","doi":"10.4012/dmj.2024-366","DOIUrl":"https://doi.org/10.4012/dmj.2024-366","url":null,"abstract":"<p><p>The encapsulation and the release of ascorbate-2-phosphate (AsAP) and β-glycerophosphate (β-GP) in microspheres (MSs) consist of poly(lactide-co-glycolide) (PLGA) and poly(ε-caploractone) (PCL) with octacalcium phosphate (OCP) were studied. AsAP-loaded PLGA/PCL (50:50) MSs (AsAP-MSs) were prepared using a water-in-oil-in-water emulsion evaporation. β-GP-loaded PLGA/PCL MSs (β-GP-MS) were prepared similarly while β-GP was directly added in oil. The oil phase dichloromethane was evaporated producing pores in MSs. MSs were characterized by physical techniques such as Fourier transform infrared spectroscopy (FTIR). The drug encapsulation efficiency (E.E.) was evaluated by spectrophotometer after water-extracting. The drug releases into supernatant were analyzed after incubating in 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid (HEPES)-NaCl buffer at 37°C for 36 days. E.E. was 89% for AsAP and 67% for β-GP, and AsAp was released immediately while β-GP was continuously released. OCP was hydrolyzed to hydroxyapatite, affecting β-GP release. PLGA/PCL MSc with OCP may be effective for the release of osteogenic factors.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"C2C12 myoblast differentiation stimulated by octacalcium phosphate material.","authors":"Howard Tu-Shen Chen, Yukari Shiwaku, Ryo Hamai, Kaori Tsuchiya, Kensuke Yamauchi, Tetsu Takahashi, Osamu Suzuki","doi":"10.4012/dmj.2024-382","DOIUrl":"https://doi.org/10.4012/dmj.2024-382","url":null,"abstract":"<p><p>To know about whether a bone substitute material octacalcium phosphate (OCP) is associated with bone formation by acting on surrounding tissue-derived cells, such as muscle cells, the effect of OCP was investigated on muscle-derived myoblast C2C12 cells in vitro. C2C12 cells were cultured with or without OCP granules. The diameter of the myotube formed from C2C12 cells with OCP was larger than that without OCP. mRNA expressions of myoblast differentiation markers (MyHC, MCK) and myokine (FGF-2) were increased by OCP, while Fndc5 and osteoglycin (myokine) were decreased. The alkaline phosphatase activity of mesenchymal stem cells was increased by adding the extract of media cultured with C2C12 cells and OCP up to 14 days. The chemical and spectroscopic analyses indicated that OCP hydrolysis progressed towards Ca-deficient hydroxyapatite in the media. The results suggest that OCP promotes myoblast differentiation and assists osteoblast differentiation through the myokines secretion under the environment induced by OCP hydrolysis.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryo Hamai, Kenya Tomitsuka, Masahiro Okada, Kaori Tsuchiya, Tai Kimura, Susumu Sakai, Kensuke Yamauchi, Osamu Suzuki
{"title":"Osteoclast formation in the co-presence of octacalcium phosphate and inorganic phosphorus-containing gelatin in vitro.","authors":"Ryo Hamai, Kenya Tomitsuka, Masahiro Okada, Kaori Tsuchiya, Tai Kimura, Susumu Sakai, Kensuke Yamauchi, Osamu Suzuki","doi":"10.4012/dmj.2024-367","DOIUrl":"https://doi.org/10.4012/dmj.2024-367","url":null,"abstract":"<p><p>This study was designed to investigate the effect of biodegradable octacalcium phosphate (OCP) bone substitute on osteoclast formation under the higher inorganic phosphorus concentration in vitro. We developed the gelatin particles releasing inorganic phosphate (Pi) ions as a model to change the local Pi ion concentration around OCP in the OCP/gelatin composite materials. Spectroscopic and chemical analyses indicated that Pi ion released around 2 mmol/L from gelatin particles promoted OCP hydrolysis, although excessive Pi ion release up to around 3 mmol/L suppressed the hydrolysis. The formation of tartrate-resistant acid phosphatase (TRAP)-positive multinuclear cells was increased by the OCP hydrolysis promotion via modulately higher Pi release Pi ion release. However, OCP hydrolysis suppression by excessive Pi ion release decreased the formation of TRAP-positive cells. The present study suggests that the chemical environment induced by OCP hydrolysis under a suitable Pi ion concentration could be associated with promoting osteoclast formation.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}