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Impact of restorative material on fracture behaviors of class II restoration in endodontically treated deciduous molars. 修复材料对经牙髓治疗的脱落磨牙 II 类修复体断裂行为的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-08-28 DOI: 10.4012/dmj.2024-067
Kanae Wada, Junichiro Wada, Mine Betul Uctasli, Sadullah Uctasli, Yasemin Yavuz, Tsutomu Iwamoto, Pekka K Vallittu, Sufyan Garoushi, Lippo Lassila
{"title":"Impact of restorative material on fracture behaviors of class II restoration in endodontically treated deciduous molars.","authors":"Kanae Wada, Junichiro Wada, Mine Betul Uctasli, Sadullah Uctasli, Yasemin Yavuz, Tsutomu Iwamoto, Pekka K Vallittu, Sufyan Garoushi, Lippo Lassila","doi":"10.4012/dmj.2024-067","DOIUrl":"https://doi.org/10.4012/dmj.2024-067","url":null,"abstract":"<p><p>The purpose of this study was to investigate the fracture behavior of endodontically treated (ET) deciduous molar when directly restored with different restorative materials in Class II (MO) cavities in comparison with permanent teeth. MO cavities were prepared with 2.4-2.5 mm and 1.9-2.0 mm in buccolingual width, and mesiodistal width of each cavity walls, respectively, followed by direct restoration with different materials: resin-modified glass ionomer cement (RMGIC), composite resin (CR), and composite resin containing 25% short glass-fiber (SFRC). All specimens were subjected to mechanical loading tests at a speed of 1 mm/min and evaluated fracture resistance and fracture modes. A one-way ANOVA followed by a Tukey multiple comparisons analysis was used. Deciduous-SFRC (3,310.5±396.2 N) were significantly higher fracture resistance than permanent-RMGIC (1,633.8±346.8 N) (p<0.001), and permanent-CR (1,400.0±381.3 N) (p<0.001). For the direct restoration of MO cavity after endodontic treatment, SFRC demonstrated its promising performance in load-bearing capacity and failure mode, especially in ET deciduous molars.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142092518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dimensional reliability in CAD/CAM production of complete denture bases: A comparative study of milling and various 3D printing technologies. 全口义齿基托 CAD/CAM 生产中的尺寸可靠性：铣削和各种三维打印技术的比较研究。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-08-10 DOI: 10.4012/dmj.2023-215
Tobias Graf, Josef Schweiger, Janosch Goob, Michael Stimmelmayr, Isabel Lente, Oliver Schubert
{"title":"Dimensional reliability in CAD/CAM production of complete denture bases: A comparative study of milling and various 3D printing technologies.","authors":"Tobias Graf, Josef Schweiger, Janosch Goob, Michael Stimmelmayr, Isabel Lente, Oliver Schubert","doi":"10.4012/dmj.2023-215","DOIUrl":"https://doi.org/10.4012/dmj.2023-215","url":null,"abstract":"<p><p>This study aims to assess the dimensional accuracy of complete denture bases fabricated from different CAD/CAM technologies and a conventional method, including milling (CNC), PolyJet (PJ), laser sintering (SLS), digital light processing (DLP), and injection molding (IM). It also examines the influence of the removal of technology-specific connectors or support structures when present. Denture base surfaces were digitized using a laboratory scanner, and virtual measurement points were calculated with tetrahedral reference geometries. Defined distances were measured in all spatial directions and compared to design data (p<0.05), revealing significant differences in sagittal (p=0.004), transversal (p<0.001), and vertical (p<0.001) dimensions. Connector removal had no significant impact for CNC but significantly affected DLP. All technologies yielded clinically acceptable results, with CNC milling demonstrating the best overall outcome.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141970844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomimetic concentric microgrooved titanium surfaces influence bone marrow-derived mesenchymal stem cell osteogenic differentiation via H3K4 trimethylation epigenetic regulation. 仿生同心微槽钛表面通过 H3K4 三甲基化表观遗传调控影响骨髓间充质干细胞成骨分化。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-08-10 DOI: 10.4012/dmj.2023-327
Hong Wang, Xinze Weng, Yan Chen, Shunjie Mao, Yuerong Gao, Qinglin Wu, Yanling Huang, Xin Guan, Zhiqiang Xu, Yingzhen Lai
{"title":"Biomimetic concentric microgrooved titanium surfaces influence bone marrow-derived mesenchymal stem cell osteogenic differentiation via H3K4 trimethylation epigenetic regulation.","authors":"Hong Wang, Xinze Weng, Yan Chen, Shunjie Mao, Yuerong Gao, Qinglin Wu, Yanling Huang, Xin Guan, Zhiqiang Xu, Yingzhen Lai","doi":"10.4012/dmj.2023-327","DOIUrl":"https://doi.org/10.4012/dmj.2023-327","url":null,"abstract":"<p><p>Material surface micromorphology can modulate cellular behavior and promote osteogenic differentiation through cytoskeletal rearrangement. Bone reconstruction requires precise regulation of gene expression in cells, a process governed by epigenetic mechanisms such as histone modifications, DNA methylation, and chromatin remodeling. We constructed osteon-mimetic concentric microgrooved titanium surfaces with different groove sizes and cultured bone marrow-derived mesenchymal stem cells (BMSCs) on the material surfaces to study how they regulate cell biological behavior and osteogenic differentiation through epigenetics. We found that the cells arranged in concentric circles along the concentric structure in the experimental group, and the concentric microgrooved surface did not inhibit cell proliferation. The results of a series of osteogenic differentiation experiments showed that the concentric microgrooves facilitated calcium deposition and promoted osteogenic differentiation of the BMSCs. Concentric microgrooved titanium surfaces that were 30 μm wide and 10 μm deep promoted osteogenic differentiation of BMSC by increasing WDR5 expression via H3K4 trimethylation upregulation.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141970842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Finite element analysis of fatigue life of commercially pure titanium clasps additively manufactured with different building orientations. 对采用不同建筑方向快速制造的商用纯钛扣疲劳寿命进行有限元分析。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-08-09 DOI: 10.4012/dmj.2024-023
Kento Odaka, Mikiya Sugano, Taichi Kawamoto, Naoki Takano, Satoru Matsunaga
{"title":"Finite element analysis of fatigue life of commercially pure titanium clasps additively manufactured with different building orientations.","authors":"Kento Odaka, Mikiya Sugano, Taichi Kawamoto, Naoki Takano, Satoru Matsunaga","doi":"10.4012/dmj.2024-023","DOIUrl":"https://doi.org/10.4012/dmj.2024-023","url":null,"abstract":"<p><p>The geometrical accuracy of additively manufactured pure titanium clasps depends on the building orientation. The aim of this study is to compare the geometrical accuracy and the fatigue lives predicted by finite element analysis (FEA) among three clasps manufactured with different building orientations. Besides, this paper proposed a calculation method of the moment of inertia of area and cross-sectional area along with the arm as the geometrical parameters. One of the clasps manufactured with a cylindrical chucking part for the fatigue test had almost the same geometrical parameters with the CAD design. Also, the authors' fatigue life prediction method using the CAD based FEA was verified through comparison with micro-CT image-based FEA. The other two clasps had larger geometrical parameters than the CAD design, resulting in longer fatigue lives. The results implied the importance of calculating the moment of inertia of the area in the design of the clasp arm.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141970845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of polishing methods for two types of monolithic all-ceramic crowns after occlusal adjustments: Polishing paste versus glazed porcelain. 咬合调整后两种整体全瓷冠抛光方法的比较：抛光膏与釉瓷
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-08-09 DOI: 10.4012/dmj.2024-058
Syuntaro Nomoto, Mizuho Hirano, Yu Tsuyuki, Takanori Sakai, Mamoru Yotsuya, Hideshi Sekine
{"title":"Comparison of polishing methods for two types of monolithic all-ceramic crowns after occlusal adjustments: Polishing paste versus glazed porcelain.","authors":"Syuntaro Nomoto, Mizuho Hirano, Yu Tsuyuki, Takanori Sakai, Mamoru Yotsuya, Hideshi Sekine","doi":"10.4012/dmj.2024-058","DOIUrl":"https://doi.org/10.4012/dmj.2024-058","url":null,"abstract":"<p><p>This study compared the effects of two surface preparation methods on two types of zirconia. Immediately prior to the placement of a monolithic zirconia crown, its morphology may be modified using a rotary cutting instrument for occlusal adjustments. The crown surface is scratched during the grinding process and, thus, requires polishing. Simplified zirconia crowns of 3Y and 5Y were fabricated and used as specimens. The surface roughness and gloss of the occlusal surfaces of specimens were measured and compared when a polishing compound was used after polishing points and when a silica-based coating was sintered. No significant differences were observed in surface roughness between 3Y and 5Y zirconia. The use of polishing compounds was effective because polishing points alone only resulted in a level of surface roughness that may cause wear on antagonist teeth. Although the silica-based coating improved surface properties, the polishing compound more effectively improved surface roughness.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141970843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental study of the biological properties of nmHA-SiO2 fiber materials prepared by electrospinning technology. 电纺丝技术制备的 nmHA-SiO2 纤维材料生物特性的实验研究。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-07-31 Epub Date: 2024-06-07 DOI: 10.4012/dmj.2023-274
Wenyun Zhang, Yuhan Zheng, Cheng Yang, Zhimin Yu, Yuan Zhao, Li Yang, Yanbo Li, Qing Liu, Chongyan Xu, Jun Su, Tingting Yan
{"title":"Experimental study of the biological properties of nmHA-SiO<sub>2</sub> fiber materials prepared by electrospinning technology.","authors":"Wenyun Zhang, Yuhan Zheng, Cheng Yang, Zhimin Yu, Yuan Zhao, Li Yang, Yanbo Li, Qing Liu, Chongyan Xu, Jun Su, Tingting Yan","doi":"10.4012/dmj.2023-274","DOIUrl":"10.4012/dmj.2023-274","url":null,"abstract":"<p><p>To study the biocompatibility of nanohydroxyapatite (nmHA)-SiO<sub>2</sub> fiber material and its efficacy in guided bone regeneration. ① The cytotoxicity of the nmHA-SiO<sub>2</sub> fiber material to MC3T3-E1 cells was determined by CCK-8 assay. The adhesion of cells on the surface of the material was observed. ② Bone defects were prepared in the skull of three groups of New Zealand white rabbits. The following treatments were administered: implantation of nmHA-SiO<sub>2</sub>, implantation of Bio-Oss, and no treatment. The defects were then covered with nmHA-SiO<sub>2</sub> membrane or Hai'ao oral repair membrane. Animal samples were analyzed by gross observation, micro-computed tomography, hematoxylin-eosin staining and Masson staining. The data were statistically analyzed by multivariate analysis of variance to evaluate the repair of bone defects. ① The nmHA-SiO<sub>2</sub> fiber material has suitable biocompatibility. ② The nmHA-SiO<sub>2</sub> fiber material performed more effectively as a barrier membrane than other bone substitute materials in GBR model rabbits.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of plasma surface treatment on the bond strength of zirconia with an adhesive resin luting agent. 等离子体表面处理对氧化锆与粘合剂树脂胶合剂粘接强度的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-07-31 Epub Date: 2024-07-04 DOI: 10.4012/dmj.2024-051
Shoko Miura, Masanori Fujisawa, Pekka Vallittu, Lippo Lassila
{"title":"Effects of plasma surface treatment on the bond strength of zirconia with an adhesive resin luting agent.","authors":"Shoko Miura, Masanori Fujisawa, Pekka Vallittu, Lippo Lassila","doi":"10.4012/dmj.2024-051","DOIUrl":"10.4012/dmj.2024-051","url":null,"abstract":"<p><p>The purpose of this study was to evaluate the effect of the atmospheric pressure plasma treatment as a surface treatment method on the contact angle and shear bond strength (SBS) of zirconia ceramics and the failure mode between the self-adhesive resin luting agent and zirconia. The zirconia specimens were divided into eight groups based on the surface treatment method: alumina blasting, air plasma, argon plasma (AP), Katana cleaner, ozonated water, ozonated water+AP, Katana cleaner+AP, and tap water+AP. The contact angles, SBS, and fracture modes were tested. AP treatment significantly reduced the contact angle (p<0.0001). The combination of AP and other cleaning methods showed a higher bond strength and more mixed fractures. Our findings indicate that using atmospheric pressure plasma with argon gas, combined with other cleaning methods, results in a stronger bond than when using alumina blasting alone.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141497379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Depth of cure, water absorption, and solubility of indirect composites polymerized by light-emitting diode laboratory units. 发光二极管实验室装置聚合的间接复合材料的固化深度、吸水性和溶解性。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-07-31 Epub Date: 2024-06-29 DOI: 10.4012/dmj.2023-260
Hideyuki Imai, Hiroyasu Koizumi, Haruto Hiraba, Kaori Kiuchi, Hideo Matsumura, Takayuki Yoneyama
{"title":"Depth of cure, water absorption, and solubility of indirect composites polymerized by light-emitting diode laboratory units.","authors":"Hideyuki Imai, Hiroyasu Koizumi, Haruto Hiraba, Kaori Kiuchi, Hideo Matsumura, Takayuki Yoneyama","doi":"10.4012/dmj.2023-260","DOIUrl":"10.4012/dmj.2023-260","url":null,"abstract":"<p><p>This study investigated the usefulness of a dental laboratory polymerization unit with light-emitting diode (LED) as a light source. The depth of cure (n=15), water absorption and solubility (n=9) of two indirect composite materials (Cesead N and Solidex Hardura) were evaluated by five dental laboratory polymerization units (LED Cure Master, Twinkle LED, α-Light V, α-Light II, and Hyper LII). Statistical analysis was performed by one-way ANOVA and Tukey test or non-parametric tests. Comparison of light sources for curing depth showed that metal halide had the highest value, followed by the LED group with similar values, and halogen lamps with the lowest value. The water absorption and solubility of the composite specimens polymerized with the three LED laboratory polymerization units were within the ISO recommended limit.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141466827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The research status and future direction of polyetheretherketone in dental implant -A comprehensive review. 聚醚醚酮在牙科植入物中的研究现状和未来方向--全面综述。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-07-31 DOI: 10.4012/dmj.2024-076
Yaqi Hao, Changquan Shi, Yuwei Zhang, Rui Zou, Shaojie Dong, Chuncheng Yang, Lin Niu
{"title":"The research status and future direction of polyetheretherketone in dental implant -A comprehensive review.","authors":"Yaqi Hao, Changquan Shi, Yuwei Zhang, Rui Zou, Shaojie Dong, Chuncheng Yang, Lin Niu","doi":"10.4012/dmj.2024-076","DOIUrl":"https://doi.org/10.4012/dmj.2024-076","url":null,"abstract":"<p><p>Currently, dental implants primarily rely on the use of titanium and titanium alloys. However, the extensive utilization of these materials in clinical practice has unveiled various problems including stress shielding, corrosion, allergic reactions, cytotoxicity, and image artifacts. As a result, polyetheretherketone (PEEK) has emerged as a notable alternative due to its favorable mechanical properties, corrosion resistance, wear resistance, biocompatibility, radiation penetrability and MRI compatibility. Meanwhile, the advancement and extensive application of 3D printing technology has expanded the range of medical applications for PEEK, including artificial spines, skulls, ribs, shinbones, hip joints, and temporomandibular joints. In this review, we aim to assess the advantages and disadvantages of PEEK as a dental implant material, summarize the measures taken to address its shortcomings and their effects, and provide insight into the future potential of PEEK in dental implant applications, with the goal of offering guidance and reference for future research endeavors.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of bioceramic sealer residues on the adhesion interface with a universal adhesive in the etch-and-rinse strategy, based on the application protocol and evaluation time. 生物陶瓷密封剂残留物对蚀刻-冲洗策略中通用粘合剂粘合界面的影响，基于应用方案和评估时间。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-07-31 Epub Date: 2024-06-01 DOI: 10.4012/dmj.2024-046
Joatan Lucas de Sousa Gomes Costa, Antonia Patricia Oliveira Barros, Mariana Bena Gelio, Lucas David Galvani, Luis Geraldo Vaz, Milton Carlos Kuga
{"title":"Influence of bioceramic sealer residues on the adhesion interface with a universal adhesive in the etch-and-rinse strategy, based on the application protocol and evaluation time.","authors":"Joatan Lucas de Sousa Gomes Costa, Antonia Patricia Oliveira Barros, Mariana Bena Gelio, Lucas David Galvani, Luis Geraldo Vaz, Milton Carlos Kuga","doi":"10.4012/dmj.2024-046","DOIUrl":"10.4012/dmj.2024-046","url":null,"abstract":"<p><p>The aim of this study was to evaluate the effects of the application of universal adhesive in the etch-and-rinse (ER) strategy with a manual brush (MB) or rotary brush (RB) in adhesion to dentin impregnated (WB) or not (NB) with bioceramic sealer, at 24 h and 1 year. Eighty-eight crowns of bovine incisors were divided into four groups (n=22): WB-MB, WB-RB, NB-MB, NB-RB. After the restorative protocol, dentin penetrability was evaluated by confocal microscopy. Bond strength was evaluated by microtensile test. Data were analyzed using one-way ANOVA/Tukey tests (α=0.05). NB-RB and WB-RB exhibited greater extensions of resin tags in dentin. At 24 h, WB-RB and NB-MB showed the highest and lowest values of bond strength, respectively. At 1 year, WB-MB and WB-RB demonstrated the highest bond strength values. The RB increases the formation of resin tags and residues of bioceramic sealer provides higher bond strength in the ER strategy.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141199319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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