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Surface roughness associated with bacterial adhesion on dental resin-based materials. 牙科树脂基材料表面粗糙度与细菌粘附的关系
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-09-28 Epub Date: 2024-08-30 DOI: 10.4012/dmj.2023-234
Oskar Bunz, Max Diekamp, Mozhgan Bizhang, Holger Testrich, Andree Piwowarczyk
{"title":"Surface roughness associated with bacterial adhesion on dental resin-based materials.","authors":"Oskar Bunz, Max Diekamp, Mozhgan Bizhang, Holger Testrich, Andree Piwowarczyk","doi":"10.4012/dmj.2023-234","DOIUrl":"10.4012/dmj.2023-234","url":null,"abstract":"<p><p>This study investigates the surface quality and bacterial adhesion properties of various dental materials, including indirect composites, veneering composites, direct composites, polyether ether ketone (PEEK), and two millable polymethyl methacrylate (PMMA). Material specimens were processed following manufacturer instructions, initially evaluated for surface roughness and Streptococcus sanguinis (S. sanguinis) adhesion. Subsequently, toothbrushing simulation was employed to simulate aging, and changes in material surfaces were assessed via roughness measurements and bacterial adhesion testing. Prior to simulated aging, direct and indirect composites exhibited the lowest roughness values. However, after the simulated toothbrushing, veneering composites displayed the highest roughness levels. Both PMMA materials demonstrated the highest S. sanguinis adhesion levels, both before and after artificial aging. Interestingly, the indirect composite material showed a reduction in bacterial adhesion following toothbrushing simulation. Surprisingly, this study did not reveal a clear correlation between roughness and bacterial adhesion.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of restorative material on fracture behaviors of class II restoration in endodontically treated deciduous molars. 修复材料对经牙髓治疗的脱落磨牙 II 类修复体断裂行为的影响。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-09-28 Epub Date: 2024-08-28 DOI: 10.4012/dmj.2024-067
Kanae Wada, Junichiro Wada, Mine Betul Uctasli, Sadullah Uctasli, Yasemin Yavuz, Tsutomu Iwamoto, Pekka K Vallittu, Sufyan Garoushi, Lippo Lassila
{"title":"Impact of restorative material on fracture behaviors of class II restoration in endodontically treated deciduous molars.","authors":"Kanae Wada, Junichiro Wada, Mine Betul Uctasli, Sadullah Uctasli, Yasemin Yavuz, Tsutomu Iwamoto, Pekka K Vallittu, Sufyan Garoushi, Lippo Lassila","doi":"10.4012/dmj.2024-067","DOIUrl":"10.4012/dmj.2024-067","url":null,"abstract":"<p><p>The purpose of this study was to investigate the fracture behavior of endodontically treated (ET) deciduous molar when directly restored with different restorative materials in Class II (MO) cavities in comparison with permanent teeth. MO cavities were prepared with 2.4-2.5 mm and 1.9-2.0 mm in buccolingual width, and mesiodistal width of each cavity walls, respectively, followed by direct restoration with different materials: resin-modified glass ionomer cement (RMGIC), composite resin (CR), and composite resin containing 25% short glass-fiber (SFRC). All specimens were subjected to mechanical loading tests at a speed of 1 mm/min and evaluated fracture resistance and fracture modes. A one-way ANOVA followed by a Tukey multiple comparisons analysis was used. Deciduous-SFRC (3,310.5±396.2 N) were significantly higher fracture resistance than permanent-RMGIC (1,633.8±346.8 N) (p<0.001), and permanent-CR (1,400.0±381.3 N) (p<0.001). For the direct restoration of MO cavity after endodontic treatment, SFRC demonstrated its promising performance in load-bearing capacity and failure mode, especially in ET deciduous molars.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142092518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in the surface texture of pre-polymerized acrylic resin pediatric crowns following acidulated phosphate fluoride application. 预聚合丙烯酸树脂儿科牙冠在使用酸性磷酸盐氟化物后表面纹理的变化。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-09-28 Epub Date: 2024-08-30 DOI: 10.4012/dmj.2024-083
Keiya Nanri, Hiroyasu Koizumi, Haruto Hiraba, Takashi Kikuiri, Takayuki Yoneyama
{"title":"Changes in the surface texture of pre-polymerized acrylic resin pediatric crowns following acidulated phosphate fluoride application.","authors":"Keiya Nanri, Hiroyasu Koizumi, Haruto Hiraba, Takashi Kikuiri, Takayuki Yoneyama","doi":"10.4012/dmj.2024-083","DOIUrl":"10.4012/dmj.2024-083","url":null,"abstract":"<p><p>This study aimed to investigate the effect of acidulated phosphate fluoride (APF) application on filler-free polymethyl methacrylate (PMMA)-based resin blocks for computer-aided design/computer-aided manufacturing (CAD-CAM), focusing on their use in pediatric crowns. Three types of PMMA-based blocks for CAD-CAM were evaluated, and a composite resin block for CAD-CAM was used as a control. Statistical analysis (p<0.05) of the data revealed that all PMMA-based blocks showed significantly higher gloss levels than the composite resin blocks. Two PMMA-based blocks also demonstrated significantly lower Ra and Sa values. SEM images showed no irregular changes in the surface properties of the PMMA-based blocks compared to those of the composite resin block. These results are significant in meeting the increasing demand for esthetic restorative treatments in pediatrics, where APF is commonly used for caries prevention. PMMA-based resin blocks for CAD-CAM are an effective alternative to prevent esthetic degradation from gloss reduction and plaque accumulation.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Finite element analysis of fatigue life of commercially pure titanium clasps additively manufactured with different building orientations. 对采用不同建筑方向快速制造的商用纯钛扣疲劳寿命进行有限元分析。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-09-28 Epub Date: 2024-08-09 DOI: 10.4012/dmj.2024-023
Kento Odaka, Mikiya Sugano, Taichi Kawamoto, Naoki Takano, Satoru Matsunaga
{"title":"Finite element analysis of fatigue life of commercially pure titanium clasps additively manufactured with different building orientations.","authors":"Kento Odaka, Mikiya Sugano, Taichi Kawamoto, Naoki Takano, Satoru Matsunaga","doi":"10.4012/dmj.2024-023","DOIUrl":"10.4012/dmj.2024-023","url":null,"abstract":"<p><p>The geometrical accuracy of additively manufactured pure titanium clasps depends on the building orientation. The aim of this study is to compare the geometrical accuracy and the fatigue lives predicted by finite element analysis (FEA) among three clasps manufactured with different building orientations. Besides, this paper proposed a calculation method of the moment of inertia of area and cross-sectional area along with the arm as the geometrical parameters. One of the clasps manufactured with a cylindrical chucking part for the fatigue test had almost the same geometrical parameters with the CAD design. Also, the authors' fatigue life prediction method using the CAD based FEA was verified through comparison with micro-CT image-based FEA. The other two clasps had larger geometrical parameters than the CAD design, resulting in longer fatigue lives. The results implied the importance of calculating the moment of inertia of the area in the design of the clasp arm.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141970845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Collagen-binding bone morphogenetic protein-2 designed for use in bone tissue engineering. 胶原结合型骨形态发生蛋白-2，设计用于骨组织工程。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-09-28 Epub Date: 2024-08-30 DOI: 10.4012/dmj.2024-138
Karina Erda Saninggar, Fumika Abe, Ayana Nakano, Koichi Kato
{"title":"Collagen-binding bone morphogenetic protein-2 designed for use in bone tissue engineering.","authors":"Karina Erda Saninggar, Fumika Abe, Ayana Nakano, Koichi Kato","doi":"10.4012/dmj.2024-138","DOIUrl":"10.4012/dmj.2024-138","url":null,"abstract":"<p><p>Bone tissue engineering using biodegradable porous scaffolds is a promising approach for restoring oral and maxillofacial bone defects. Recently, attempts have been made to incorporate proteins such as growth factors to create bioactive scaffolds that can engage cells to promote tissue formation. Collagen-based scaffolds containing bone morphogenetic protein-2 (BMP2) have been studied for bone formation. However, controlling the initial burst of BMP2 remains difficult. Here we designed a functional chimeric protein composed of BMP2 and a collagen-binding domain (CBD), specifically the A3 domain of von Willebrand factor, to sustain BMP2 release from collagen-based scaffolds. Based on the results of computer-based structural prediction, we prepared a chimeric protein consisting of CBD and BMP2 in this order with a peptide tag for affinity purification. The chimeric protein had a collagen-binding capacity and enhanced osteogenic differentiation of human mesenchymal stem cells. These results are consistent with insights from in silico structural prediction.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical and physical properties of radiopaque Portland cement formulation with reduced particle size. 粒径减小的不透射线硅酸盐水泥配方的化学和物理特性。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-09-28 Epub Date: 2024-09-10 DOI: 10.4012/dmj.2024-015
Hoda Mohamed Elnawawy, Muralithran Govindan Kutty, Noor Azlin Yahya, Noor Hayaty Abu Kasim, Paul Roy Cooper, Josette Camilleri, Hany Mohamed Aly Ahmed
{"title":"Chemical and physical properties of radiopaque Portland cement formulation with reduced particle size.","authors":"Hoda Mohamed Elnawawy, Muralithran Govindan Kutty, Noor Azlin Yahya, Noor Hayaty Abu Kasim, Paul Roy Cooper, Josette Camilleri, Hany Mohamed Aly Ahmed","doi":"10.4012/dmj.2024-015","DOIUrl":"10.4012/dmj.2024-015","url":null,"abstract":"<p><p>This study compared the chemical and physical properties of an experimental radiopaque white Portland cement (REPC) with reduced particle size to ProRoot white mineral trioxide aggregate (WMTA). The particle size distribution of experimental Portland cement (EPC) was examined, and then nano-zirconium oxide (nano-ZrO) was added to produce REPC. Chemical analysis, initial setting time, pH values, and push-out bond strength were evaluated. Results showed that REPC had smallest particle size (354.5±26.45 nm), while PC had the largest (1,309.67±60.54 nm) (p<0.05). Differences in chemical composition were observed. REPC exhibited shorter setting time (32.7±0.58 min) compared to WMTA (131.67±2.89 min) and PC (163.33±2.89 min) (p<0.05). All groups showed alkaline pH (p<0.05). REPC demonstrated the highest push-out bond strength (22.24±4.33 MPa) compared with WMTA (15.53±3.26 MPa) and PC (16.8±5.43 MPa) (p<0.05). This cost-effective PC formulation reduced the setting time and increased the push-out bond strength while maintaining the alkaline properties of the original cements.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of polishing methods for two types of monolithic all-ceramic crowns after occlusal adjustments: Polishing paste versus glazed porcelain. 咬合调整后两种整体全瓷冠抛光方法的比较：抛光膏与釉瓷
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-09-28 Epub Date: 2024-08-09 DOI: 10.4012/dmj.2024-058
Syuntaro Nomoto, Mizuho Hirano, Yu Tsuyuki, Takanori Sakai, Mamoru Yotsuya, Hideshi Sekine
{"title":"Comparison of polishing methods for two types of monolithic all-ceramic crowns after occlusal adjustments: Polishing paste versus glazed porcelain.","authors":"Syuntaro Nomoto, Mizuho Hirano, Yu Tsuyuki, Takanori Sakai, Mamoru Yotsuya, Hideshi Sekine","doi":"10.4012/dmj.2024-058","DOIUrl":"10.4012/dmj.2024-058","url":null,"abstract":"<p><p>This study compared the effects of two surface preparation methods on two types of zirconia. Immediately prior to the placement of a monolithic zirconia crown, its morphology may be modified using a rotary cutting instrument for occlusal adjustments. The crown surface is scratched during the grinding process and, thus, requires polishing. Simplified zirconia crowns of 3Y and 5Y were fabricated and used as specimens. The surface roughness and gloss of the occlusal surfaces of specimens were measured and compared when a polishing compound was used after polishing points and when a silica-based coating was sintered. No significant differences were observed in surface roughness between 3Y and 5Y zirconia. The use of polishing compounds was effective because polishing points alone only resulted in a level of surface roughness that may cause wear on antagonist teeth. Although the silica-based coating improved surface properties, the polishing compound more effectively improved surface roughness.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141970843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrosion behavior of Zr-14Nb-5Ta-1Mo alloy in simulated body fluid. Zr-14Nb-5Ta-1Mo 合金在模拟体液中的腐蚀行为。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-09-21 DOI: 10.4012/dmj.2024-158
Tomoyo Manaka, Yusuke Tsutsumi, Maki Ashida, Peng Chen, Takao Hanawa
{"title":"Corrosion behavior of Zr-14Nb-5Ta-1Mo alloy in simulated body fluid.","authors":"Tomoyo Manaka, Yusuke Tsutsumi, Maki Ashida, Peng Chen, Takao Hanawa","doi":"10.4012/dmj.2024-158","DOIUrl":"https://doi.org/10.4012/dmj.2024-158","url":null,"abstract":"<p><p>Metals that are used to reconstruct skeletal structures often interfere with magnetic resonance imaging (MRI) owing to differences in magnetic susceptibility; consequently, metals with lower magnetic susceptibilities need to be developed for use in implant devices. Herein, we investigated the corrosion properties of the Zr-14Nb-5Ta-1Mo alloy, which exhibits low magnetic susceptibility and excellent mechanical properties. The pitting potential of Zr-14Nb-5Ta-1Mo was higher than that of pure Zr. The passive current density of Zr-14Nb-5Ta-1Mo also higher than that of pure Zr, which is ascribable to slow reconstruction of the initial passive film associated with the presence of Nb and Ta. XPS revealed that the passive film is enriched with Nb and Ta. Therefore, while the Zr-14Nb-5Ta-1Mo alloy exhibited a high initial passive current density in simulated body fluid, it formed a stable passive film that suppressed localized corrosion. Zr-14Nb-5Ta-1Mo is therefore a prospective implant-material alloy candidate.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wear characteristics of resin-based luting agents used in the bonded CAD-CAM resin blocks. 粘接 CAD-CAM 树脂块中使用的树脂基胶结剂的磨损特性。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-09-21 DOI: 10.4012/dmj.2024-137
Hiroto Takenaka, Keiichi Yoshida, Takashi Sawase
{"title":"Wear characteristics of resin-based luting agents used in the bonded CAD-CAM resin blocks.","authors":"Hiroto Takenaka, Keiichi Yoshida, Takashi Sawase","doi":"10.4012/dmj.2024-137","DOIUrl":"https://doi.org/10.4012/dmj.2024-137","url":null,"abstract":"<p><p>This study aimed to investigate the wear and microhardness of luting agents and computer-aided design-computer-aided manufacturing (CAD-CAM) resin blocks, and to compare the wear characteristics of resin-based luting agents used in bonded specimens of CAD-CAM resin blocks. After three-body wear test, the amount of wear and Vickers hardness were measured and Pearson's correlation coefficient was calculated. The lowest amount of wear and the highest Vickers hardness values were obtained for Estecem II. Filler loss was observed in five composite resin cements. A strong negative correlation was observed in the luting agents between the amount of wear and Vickers hardness value (r=-0.874, p<0.0001). Additionally, a strong positive correlation was observed between the amount of wear of the bonded specimen and amount of luting agent used alone (r=0.943, p<0.0001). To conclude, the wear resistance of the luting agent used in the bonded specimen was significantly influenced by the bonding between the filler and matrix resin.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental study of the biological properties of nmHA-SiO2 fiber materials prepared by electrospinning technology. 电纺丝技术制备的 nmHA-SiO2 纤维材料生物特性的实验研究。
IF 1.9 4区 医学
Dental materials journal Pub Date : 2024-07-31 Epub Date: 2024-06-07 DOI: 10.4012/dmj.2023-274
Wenyun Zhang, Yuhan Zheng, Cheng Yang, Zhimin Yu, Yuan Zhao, Li Yang, Yanbo Li, Qing Liu, Chongyan Xu, Jun Su, Tingting Yan
{"title":"Experimental study of the biological properties of nmHA-SiO<sub>2</sub> fiber materials prepared by electrospinning technology.","authors":"Wenyun Zhang, Yuhan Zheng, Cheng Yang, Zhimin Yu, Yuan Zhao, Li Yang, Yanbo Li, Qing Liu, Chongyan Xu, Jun Su, Tingting Yan","doi":"10.4012/dmj.2023-274","DOIUrl":"10.4012/dmj.2023-274","url":null,"abstract":"<p><p>To study the biocompatibility of nanohydroxyapatite (nmHA)-SiO<sub>2</sub> fiber material and its efficacy in guided bone regeneration. ① The cytotoxicity of the nmHA-SiO<sub>2</sub> fiber material to MC3T3-E1 cells was determined by CCK-8 assay. The adhesion of cells on the surface of the material was observed. ② Bone defects were prepared in the skull of three groups of New Zealand white rabbits. The following treatments were administered: implantation of nmHA-SiO<sub>2</sub>, implantation of Bio-Oss, and no treatment. The defects were then covered with nmHA-SiO<sub>2</sub> membrane or Hai'ao oral repair membrane. Animal samples were analyzed by gross observation, micro-computed tomography, hematoxylin-eosin staining and Masson staining. The data were statistically analyzed by multivariate analysis of variance to evaluate the repair of bone defects. ① The nmHA-SiO<sub>2</sub> fiber material has suitable biocompatibility. ② The nmHA-SiO<sub>2</sub> fiber material performed more effectively as a barrier membrane than other bone substitute materials in GBR model rabbits.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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