Dental materials journal最新文献_第4页

Ex-vivo study investigating modified pulp-capping glass-ionomers. 研究改性纸浆覆盖玻璃离子的离体研究。

IF 1.8 4区医学

Dental materials journal Pub Date : 2026-07-25 Epub Date: 2026-06-03 DOI: 10.4012/dmj.2025-204

Jirachaya Somudorn, Hathaitip Sritanaudomchai, Puangwan Lapthanasupkul, Parichart Naruphontjirakul, Mariano N Simon Pedano DE Piero, Bart VAN Meerbeek, Pong Pongprueksa

{"title":"Ex-vivo study investigating modified pulp-capping glass-ionomers.","authors":"Jirachaya Somudorn, Hathaitip Sritanaudomchai, Puangwan Lapthanasupkul, Parichart Naruphontjirakul, Mariano N Simon Pedano DE Piero, Bart VAN Meerbeek, Pong Pongprueksa","doi":"10.4012/dmj.2025-204","DOIUrl":"10.4012/dmj.2025-204","url":null,"abstract":"This study aimed to evaluate the influence of incorporating bioactive glass into glass-ionomer cement (GIc) as a pulp-capping material using a human tooth-pulp culture model. Experimental groups included GIc mixed with three bioglasses (45S5, 45S5.5Zn, 45S5.5Sr), β-tricalcium phosphate (TCP), ProRoot MTA, or Biodentine powder. Capping with unmodified GIc and Biodentine served as controls. Pulpal healing was assessed via histology following a 28-day culture period. Fisher's exact tests determined differences in mineral foci formation and pulp-tissue organization (p<0.05). Initiation of pulp mineralization was observed only when pulps were capped with GIc45S5 or Biodentine. While bioactive glass-modified GIcs demonstrated biocompatibility and promoted early pulpal healing (cell-rich eosinophilic zones), their mineralization potential remained lower than that of the calcium-silicate cement, Biodentine. These findings suggest that GIc45S5 offers a potential preclinical alternative for pulp-capping, though its bioactivity requires further optimization.","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"414-422"},"PeriodicalIF":1.8,"publicationDate":"2026-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148155740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Direct powder extrusion 3D printing of poly(ɛ-caprolactone)-carbonate substituted hydroxyapatite powder composites: Influence of powder content and multi-scale spatial organization on scaffold morphology and mechanical properties. 聚-己内酯-碳酸盐取代羟基磷灰石粉末复合材料的直接粉末挤出3D打印：粉末含量和多尺度空间组织对支架形态和力学性能的影响

IF 1.8 4区医学

Dental materials journal Pub Date : 2026-07-25 Epub Date: 2026-06-20 DOI: 10.4012/dmj.2025-270

Hengky Bowo Ardhiyanto, Isao Hirata, Kazuhiro Tsuga, Koichi Kato

{"title":"Direct powder extrusion 3D printing of poly(ɛ-caprolactone)-carbonate substituted hydroxyapatite powder composites: Influence of powder content and multi-scale spatial organization on scaffold morphology and mechanical properties.","authors":"Hengky Bowo Ardhiyanto, Isao Hirata, Kazuhiro Tsuga, Koichi Kato","doi":"10.4012/dmj.2025-270","DOIUrl":"10.4012/dmj.2025-270","url":null,"abstract":"Poly(ɛ-caprolactone) (PCL) is widely used in bone tissue engineering but lacks intrinsic bioactivity. In this study, carbonate substituted hydroxyapatite (CHA) was incorporated into PCL using direct powder extrusion (DPE) three-dimensional (3D) printing to fabricate scaffolds with controlled CHA contents. Structural and thermal analyses confirmed that CHA retained its apatite crystal structure and acted as a mild nucleating agent without significantly altering PCL thermal behavior. Micro-computed tomography (micro-CT) combined with multi-scale spatial statistical analysis revealed scale-dependent particle distribution, with near-random arrangements at the nearest-neighbor scale and increasing mesoscale clustering at higher CHA contents. Mechanical testing showed that compressive and tensile elastic moduli increased with CHA addition up to 10 wt%, followed by a decrease at higher loadings. Annealing enhanced elastic modulus by improving interlayer bonding and internal structural homogeneity. These findings demonstrate that CHA content and spatial particle organization govern the mechanical performance of DPE 3D printed PCL-CHA scaffolds for bone tissue engineering.","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"450-463"},"PeriodicalIF":1.8,"publicationDate":"2026-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148293739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Finite element analysis of bone resorption risk and stress distribution in anterior restorations supported by hybrid abutments produced using CAD-CAM systems. 采用CAD-CAM系统生产的混合基台支持的前牙修复体骨吸收风险和应力分布的有限元分析。

IF 1.8 4区医学

Dental materials journal Pub Date : 2026-07-25 Epub Date: 2026-07-15 DOI: 10.4012/dmj.2026-036

Cihan Akdoğan, Hatice Özdemir

引用次数: 0

CMET renovates conventional glass ionomer cement into a multifunctional pulp-protective restorative material: An in vitro study. CMET将传统的玻璃离子水门合剂改造成一种多功能护髓修复材料：一项体外研究。

IF 1.8 4区医学

Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-04-22 DOI: 10.4012/dmj.2025-283

Kohei Sato, Tomoo Yui, Yusuke Fujita, Takashi Kado, Keiji Nagano, Toshiyuki Nagasawa, Shuichi Ito

{"title":"CMET renovates conventional glass ionomer cement into a multifunctional pulp-protective restorative material: An in vitro study.","authors":"Kohei Sato, Tomoo Yui, Yusuke Fujita, Takashi Kado, Keiji Nagano, Toshiyuki Nagasawa, Shuichi Ito","doi":"10.4012/dmj.2025-283","DOIUrl":"10.4012/dmj.2025-283","url":null,"abstract":"It is essential to minimize dental pulp exposure to external stimuli to maintain pulp vitality. Therefore, pulp-protective materials require sealing ability, antibacterial activity, and biocompatibility. Conventional glass ionomer cement (GIC) possesses some of these properties, while calcium 4-methacryloxyethyl trimellitate (CMET) can induce calcification, suggesting potential utility in pulp protection. This study compared conventional GIC, CMET-modified GIC (C-GIC), and Ca-free 4-methacryloxyethyl trimellitate (4-MET)-modified GIC (4M-GIC). 4M-GIC showed decreased compressive strength and shear bond strength, whereas C-GIC exhibited only a reduction in compressive strength without affecting bond strength. Both C-GIC and 4M-GIC released increased levels of Sr2+, Ca2+, Si2+, F-, and Al3+. Notably, C-GIC demonstrated antibacterial activity comparable to that of GIC and 4M-GIC, along with lower cytotoxicity, greater cell proliferation, and increased alkaline phosphatase (ALP) activity and calcium deposition. These findings indicate that CMET incorporation enhances adhesion, ion release, antibacterial activity, and mineralization, indicating that C-GIC as a multifunctional pulp-protective material.","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"313-324"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147765265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Domain shift analysis of deep learning models for tooth detection in pediatric panoramic radiographs. 儿童全景x线片牙齿检测深度学习模型的域移分析。

IF 1.8 4区医学

Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-05-02 DOI: 10.4012/dmj.2025-301

Taku Nishimura, Yuichi Mine, Yuko Iwamoto, Shota Okazaki, Eimi Tabata, Saori Takeda, Tzu-Yu Peng, Naoya Kakimoto, Ryota Nomura, Takeshi Murayama

{"title":"Domain shift analysis of deep learning models for tooth detection in pediatric panoramic radiographs.","authors":"Taku Nishimura, Yuichi Mine, Yuko Iwamoto, Shota Okazaki, Eimi Tabata, Saori Takeda, Tzu-Yu Peng, Naoya Kakimoto, Ryota Nomura, Takeshi Murayama","doi":"10.4012/dmj.2025-301","DOIUrl":"10.4012/dmj.2025-301","url":null,"abstract":"The aim of this study was to externally validate object detection models for comprehensive tooth detection on pediatric panoramic radiographs, quantify the impact of domain shift across institutions and imaging protocols, and compare YOLOv8 and YOLOv10. Two datasets were used: an internal set of 200 images of early mixed dentition without bite blocks, and an external, open-source set of 192 images acquired with bite blocks. Performance was assessed using mean average precision (mAP), per‑class AP, precision‑recall curves, and confusion matrix. Overall performance was high but domain dependent. mAP was 0.958/0.941 (YOLOv8/v10) in Experiment 1; 0.910/0.906 in Experiment 2; and 0.906/0.901 in Experiment 3. Error analysis revealed domain‑specific failure modes: bite blocks were occasionally mistaken for the primary central incisor. Deep learning enables accurate and comprehensive detection of teeth on pediatric panoramic radiographs. However, domain shift alters error patterns and impairs the detection of rare yet clinically important classes.","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"354-364"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and characterization of natural biocomposite scaffold for bone repair: A study of gelatin-hydroxyapatite from Aceh-sourced bovine bone. 骨修复用天然生物复合支架的合成与表征：亚齐牛骨明胶-羟基磷灰石的研究。

IF 1.8 4区医学

Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-03-25 DOI: 10.4012/dmj.2025-244

Viona Diansari, Rinaldi Idroes, Sunarso, Sri Fitriyani

{"title":"Synthesis and characterization of natural biocomposite scaffold for bone repair: A study of gelatin-hydroxyapatite from Aceh-sourced bovine bone.","authors":"Viona Diansari, Rinaldi Idroes, Sunarso, Sri Fitriyani","doi":"10.4012/dmj.2025-244","DOIUrl":"10.4012/dmj.2025-244","url":null,"abstract":"This study reports the fabrication and characterization of biocomposite scaffolds combining Aceh-sourced bovine hydroxyapatite (BHA) and gelatin (GEL) for bone repair. The scaffolds were evaluated for physicochemical, mechanical, and biological properties. Fourier-transform infrared spectroscopy confirmed functional groups from both BHA and GEL. Energy-dispersive X-ray spectroscopy detected bone-related elements (Ca, P, O) and traces (Na, Mg, Al). Thermogravimetric analysis indicated thermal stability up to 600°C, and highest crystallinity (59.2%) at a 7:3 BHA:GEL ratio. Scanning electron microscopy and porosity analyses revealed an interconnected porous structure (40-295 μm pores, 72-86% porosity) supporting cell infiltration. Scaffolds exhibited favorable degradation (83-87%), swelling (675-836%), density (0.30-0.36g/cm3), compressive strength (0.22-0.44 MPa). MTT assay confirmed high osteoblast viability (78.9%), while in vivo tests demonstrated normal inflammation and accelerated bone regeneration. These findings support BHA-GEL biocomposites as cost-effective, locally sourced, biocompatible scaffolds for bone tissue engineering applications.","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"229-245"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147510187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of 2,2,2-trifluoroethyl methacrylate on the gelation characteristics of light-cured soft denture liners based on 2-ethylhexyl methacrylate and acetyl tributyl citrate. 2,2,2-三氟甲基丙烯酸乙酯对2-乙基己基甲基丙烯酸酯和柠檬酸乙酰三丁酯基光固化软性义齿衬垫凝胶化特性的影响

IF 1.8 4区医学

Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-04-22 DOI: 10.4012/dmj.2025-294

Naoya Nakashima, Sirus Safaee, Tetsurou Torisu, Riho Kanai, Kae Harada, Hiroshi Murata

{"title":"Effect of 2,2,2-trifluoroethyl methacrylate on the gelation characteristics of light-cured soft denture liners based on 2-ethylhexyl methacrylate and acetyl tributyl citrate.","authors":"Naoya Nakashima, Sirus Safaee, Tetsurou Torisu, Riho Kanai, Kae Harada, Hiroshi Murata","doi":"10.4012/dmj.2025-294","DOIUrl":"10.4012/dmj.2025-294","url":null,"abstract":"We evaluated the effects of adding the fluorinated monomer 2,2,2-trifluoroethyl methacrylate (TFEMA) and varying amounts of the plasticizer acetyl tributyl citrate (ATBC) on the gelation of light-cured soft denture liners. The liquids contained 2-ethylhexyl methacrylate (2-EHMA) and ATBC, with traces of a photo initiator and reducing agent, and the powder was poly(ethyl methacrylate/butyl methacrylate). Four 2-EHMA:TFEMA ratios and two monomer:plasticizer ratios were tested with a powder/liquid ratio of 1.0. Gelation time was measured using a controlled stress rheometer. Gelation time decreased exponentially with increasing TFEMA content in the monomer. Conversely, higher proportions of ATBC in the liquid prolonged gelation. The influence of monomer composition (2-EHMA:TFEMA) on gelation was greater than that of ATBC content. These results indicate that gelation kinetics can be widely controlled by the addition of TFEMA, and a formulation of 50 wt% monomer (2-EHMA:TFEMA=60:40)/50 wt% plasticizer (ATBC) represents a suitable liquid composition for soft denture liners.","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"274-283"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147765259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of build orientation and storage duration on the accuracy of fused deposition modeling-fabricated polyetheretherketone removable partial denture frameworks. 构建方位和存放时间对熔融沉积建模制造聚醚醚酮可摘局部义齿框架精度的影响。

IF 1.8 4区医学

Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-03-25 DOI: 10.4012/dmj.2025-280

Roubing Ha, Tamaki Hada, Chun Wei Chang, Yumika Soeda, Masanao Inokoshi, Motohiro Uo, Manabu Kanazawa

引用次数: 0

Influence of pore architecture on bone regeneration in atelocollagen scaffolds. 孔结构对游离胶原支架骨再生的影响。

IF 1.8 4区医学

Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-03-25 DOI: 10.4012/dmj.2025-229

Sara Takasugi, Kenichirou Yasui, Takeryo Adachi, Minoru Kishikawa, Jun-Ichiro Jo, Yoshiya Hashimoto, Aki Nishiura

{"title":"Influence of pore architecture on bone regeneration in atelocollagen scaffolds.","authors":"Sara Takasugi, Kenichirou Yasui, Takeryo Adachi, Minoru Kishikawa, Jun-Ichiro Jo, Yoshiya Hashimoto, Aki Nishiura","doi":"10.4012/dmj.2025-229","DOIUrl":"10.4012/dmj.2025-229","url":null,"abstract":"We aimed to compare the bone regeneration capacity of two atelocollagen sponges with distinct porosity, pore size, and pore morphology: Atelocollagen Sponge MIGHTY® (MIGHTY) and the three-dimensional Honeycomb Boosted® scaffold (Honeycomb). Scanning electron microscopy revealed that Honeycomb exhibited a continuous linear pore structure with a uniform honeycomb-like architecture, higher porosity, and larger pores than MIGHTY. Each sponge was placed in a high-density polytetrafluoroethylene dome and fixed to the rat calvaria. X-ray micro-computed tomography showed that Honeycomb increased bone volume fraction approximately 2.4-fold and 2.3-fold at 4 and 8 weeks post-implantation, respectively, compared with MIGHTY. At 12 weeks post-implantation, bone volume fraction was comparable; however, trabecular number in Honeycomb remained approximately two-fold higher. Histological and immunohistochemical observations confirmed enhanced bone formation, suggesting relatively early angiogenesis and progressive mesenchymal stem cell involvement. Overall, these results indicate that the Honeycomb scaffold supports early bone regeneration.","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"254-265"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147510241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual effects of biomimetic wave-microgrooved polycaprolactone membranes: Enhancement of osteogenesis and suppression of osteoclastogenesis. 仿生波微槽聚己内酯膜的双重作用：促进骨生成和抑制破骨细胞生成。

IF 1.8 4区医学

Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-04-08 DOI: 10.4012/dmj.2025-115

Xin Ze Weng, Xin Guan, Yi Xuan Lei, Yu Xuan Lin, Wei Xin Wang, Lu Zhang, Jing Jing Su, Ying Zhen Lai

{"title":"Dual effects of biomimetic wave-microgrooved polycaprolactone membranes: Enhancement of osteogenesis and suppression of osteoclastogenesis.","authors":"Xin Ze Weng, Xin Guan, Yi Xuan Lei, Yu Xuan Lin, Wei Xin Wang, Lu Zhang, Jing Jing Su, Ying Zhen Lai","doi":"10.4012/dmj.2025-115","DOIUrl":"10.4012/dmj.2025-115","url":null,"abstract":"Tissue engineering scaffolds with precisely engineered surface topographies have emerged as critical tools for the spatiotemporal regulation of cellular behavior in bone regeneration. Here, we propose a biomimetic approach for replicating the curvilinear architecture of native osteons through soft lithography and melt casting to fabricate polycaprolactone (PCL) membranes featuring wave-patterned microgrooves with three geometrically graded dimensions and a uniform depth of 10 μm: L1 (inner radius: 10 μm, outer radius: 20 μm), L2 (30 μm/60 μm), and L3 (60 μm/120 μm). The experimental results revealed that the wave microgrooves enhanced cell proliferation to varying degrees and that the cells utilized contact guidance to grow along the wave microgroove topographies. MC3T3-E1 cells showed more pronounced nuclear deformation in the L2 and L3 groups, while RAW264.7 cells displayed greater deformation in the L1 and L2 groups. Notably, the L3 configuration (60 μm/120 μm) demonstrated optimal dual functionality, synergistically promoting osteogenesis while inhibiting osteoclastogenesis. This unique combination of properties highlights the potential of this PCL-based guided bone regeneration (GBR) membrane for enhanced bone repair applications.","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"325-337"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147638198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0