发布求助
文献互助 智能选刊 最新文献

Dental materials journal最新文献

筛选
英文 中文
Marine mollusk shells as natural bone substitutes: Surface characterization and osteogenic activities. 作为天然骨替代物的海洋软体动物壳：表面特性和成骨活性。
IF 1.8 4区 医学
Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-04-29 DOI: 10.4012/dmj.2025-147
Kanokwan Charoonpatrapong, Woraphong Panyayong, Chanya Chuenarrom
{"title":"Marine mollusk shells as natural bone substitutes: Surface characterization and osteogenic activities.","authors":"Kanokwan Charoonpatrapong, Woraphong Panyayong, Chanya Chuenarrom","doi":"10.4012/dmj.2025-147","DOIUrl":"10.4012/dmj.2025-147","url":null,"abstract":"<p><p>Bone substitutes from various sources have been used to facilitate bone regeneration. In this study, we performed a comparative analysis of the effects of marine mollusk shells and their bioactivities on osteoblasts and osteoclasts. The results showed that the surfaces of A. granulosa and C. belcheri shells had higher surface roughness than that of P. viridis. Different surface morphologies but similar elements were found on the surfaces of all shell groups, and additional elements, particularly silicon, were found on the surface of A. granulosa. After growing osteoblasts on the shells for 4-7 days, C. belcheri, P. viridis, and A. granulosa shells had significantly more cells than P. undulata shells. Similar osteoblast differentiation was observed in all shell groups after 7-14 days. All shell groups, particularly C. belcheri and P. viridis, favored osteoclast formation. This study suggests the potential use of mollusk shells to develop alternative biocompatible bone-substitute materials.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"345-353"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147765263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of electron beam melting in pure titanium crown fabrication: An investigation of dimensional accuracy. 电子束熔化在纯钛冠制造中的应用：尺寸精度的研究。
IF 1.8 4区 医学
Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-04-24 DOI: 10.4012/dmj.2025-217
Yoshiki Ishida, Satoru Watanabe, Daisuke Miura, Yasuhiro Hotta, Akikazu Shinya
{"title":"Application of electron beam melting in pure titanium crown fabrication: An investigation of dimensional accuracy.","authors":"Yoshiki Ishida, Satoru Watanabe, Daisuke Miura, Yasuhiro Hotta, Akikazu Shinya","doi":"10.4012/dmj.2025-217","DOIUrl":"10.4012/dmj.2025-217","url":null,"abstract":"<p><p>Titanium crowns were fabricated using two types of powder bed fusion processes, electron beam melting (EBM) and selective laser melting (SLM), to investigate how building orientation affects dimensional accuracy. A cylindrical model, representing a full crown, was manufactured using both methods at three angles on the build platform (0°, 45°, and 90°). The outer and inner margin diameters, as well as the depth, were measured, and the change rates from the designed values were calculated. Additionally, the circularity of the outer and inner margins and the concentricity between them were evaluated. Results indicated larger change rates in the EBM specimens compared to the SLM specimens. The 90° specimens exhibited the highest circularity in both EBM and SLM. These findings confirmed that EBM is inferior to SLM in terms of dimensional accuracy for crown fabrication and demonstrated that the arrangement of the 3D data significantly affects accuracy.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"338-344"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147765328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization and evaluation of properties of a tissue conditioner containing co-polymerizable quaternary ammonium-based antimicrobial monomers. 含有可共聚合季铵盐抗菌单体的组织调理剂的表征和性能评价。
IF 1.8 4区 医学
Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-03-10 DOI: 10.4012/dmj.2025-257
Sowmya Rao, Vidya Pai, Ashwini Prabhu, Kishore Ginjupalli, Nandish Bantarahalli Thopegowda, Ranajit DAS, Runki Saran, Vijeesh Vijayan, Rijesh Malayathodi, Vikesh Kumar, Manojna K M
{"title":"Characterization and evaluation of properties of a tissue conditioner containing co-polymerizable quaternary ammonium-based antimicrobial monomers.","authors":"Sowmya Rao, Vidya Pai, Ashwini Prabhu, Kishore Ginjupalli, Nandish Bantarahalli Thopegowda, Ranajit DAS, Runki Saran, Vijeesh Vijayan, Rijesh Malayathodi, Vikesh Kumar, Manojna K M","doi":"10.4012/dmj.2025-257","DOIUrl":"10.4012/dmj.2025-257","url":null,"abstract":"<p><p>In this study, a commercially available tissue conditioner (TC; Soft-Liner, GC, Tokyo, Japan) was modified by incorporating quaternary ammonium salts (QAS): dimethyl-hexadecyl-methacryloxyethyl-ammonium iodide (DHMAI) and 2-dimethyl-2-dodecyl-1-methacryloxyethyl ammonium iodide (DDMAI) based on their minimum inhibitory and bactericidal concentrations (MIC and MBC). The control group consisted of TC materials without monomers. The modified TC was characterized by Fourier transform infrared spectroscopy, antimicrobial activity (microbial adherence) assessed against Streptococcus mutans (S. mutans), Staphylococcus aureus (S. aureus), and Candida albicans (C. albicans), and cytotoxicity (MTT assay) on L-929 fibroblasts. Additionally, mechanical and physical properties were assessed. Our results suggest that modified TC has effectively reduced microbial adhesion, exhibited good cytocompatibility and no significant changes were observed in the mechanical properties compared to control samples.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"266-273"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147431447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A low-toxicity ammonium hydrogen fluoride-based etchant for bonding pretreatment of silica-based CAD-CAM materials. 一种用于硅基CAD-CAM材料粘接预处理的低毒氟化氢铵基蚀刻剂。
IF 1.8 4区 医学
Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-04-29 DOI: 10.4012/dmj.2025-323
Ayako Miura, Yuya Komagata, Yuki Nagamatsu, Chihiro Masaki, Hiroshi Ikeda
{"title":"A low-toxicity ammonium hydrogen fluoride-based etchant for bonding pretreatment of silica-based CAD-CAM materials.","authors":"Ayako Miura, Yuya Komagata, Yuki Nagamatsu, Chihiro Masaki, Hiroshi Ikeda","doi":"10.4012/dmj.2025-323","DOIUrl":"10.4012/dmj.2025-323","url":null,"abstract":"<p><p>This study aimed to develop a low-toxicity etchant for bonding pretreatment of silica-based CAD-CAM materials. An experimental etchant was prepared by combining ammonium hydrogen fluoride (AHF) with ammonium hydrogen sulfate (AHS) and subsequently optimized. The optimized AHF/AHS etchant was evaluated on lithium disilicate glass, feldspathic porcelain, polymer-infiltrated ceramic network, and resin composite, and compared with hydrofluoric acid (HF), a commercial etchant (Monobond Etch & Prime; MEP), and alumina sandblasting. For lithium disilicate glass, shear bond strength (SBS) obtained with AHF/AHS treatment was higher than that with MEP but lower than that with HF. For feldspathic porcelain and polymer-infiltrated ceramic network, SBS obtained with AHF/AHS was comparable to those obtained with HF. For resin composite, SBS obtained with AHF/AHS was higher than that with untreated control while lower than that with sandblasting. Cytotoxicity evaluated using human gingival fibroblasts showed IC<sub>50</sub> values comparable to those of phosphoric acid and sodium fluoride.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"373-383"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147765294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Borneol-grafted poly(amidoamine) dendrimer with dual antimicrobial and enamel-remineralizing activities against early-stage dental caries. 冰片接枝的聚氨基胺树突状物具有抗早期龋的双重抗菌和牙釉质再矿化活性。
IF 1.8 4区 医学
Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-04-08 DOI: 10.4012/dmj.2025-317
Ziyi Qin, Ying Sha, Siyi Sun, Mengyuan Li, Fei Jiang, Yichen Zong, Jie Li, Guangdong Zhang
{"title":"Borneol-grafted poly(amidoamine) dendrimer with dual antimicrobial and enamel-remineralizing activities against early-stage dental caries.","authors":"Ziyi Qin, Ying Sha, Siyi Sun, Mengyuan Li, Fei Jiang, Yichen Zong, Jie Li, Guangdong Zhang","doi":"10.4012/dmj.2025-317","DOIUrl":"10.4012/dmj.2025-317","url":null,"abstract":"<p><p>Early caries is initiated by bacterial colonization and biofilm maturation, which drive localized demineralization of enamel. This study developed a borneol-grafted poly(amidoamine) dendrimer to inhibit bacterial adhesion, suppress biofilm formation, and enhance enamel remineralization. Borneol-grafted poly(amidoamine) dendrimer was synthesized via imine linkage and evaluated for antibacterial activity against Streptococcus mutans and Streptococcus sanguinis assessed by adhesion inhibition, and biofilm biomass/viability assays. Mechanisms were explored by zeta potential analysis and scanning electron microscopy. Remineralization was assessed by microhardness, lesion depth, mineral density, X-ray diffraction, and surface morphology; in vivo efficacy was tested on human enamel samples in an intra-oral model. Borneol-grafted poly(amidoamine) dendrimer reduced bacterial adhesion and viability, neutralized surface charge, and affected membrane integrity. In vitro, borneol-grafted poly(amidoamine) dendrimer improved hardness, reduced lesion depth, and increased mineral density; in vivo, it promoted mineralized layers without systemic toxicity. These findings indicate it as a single-scaffold preventive-restorative agent for early-stage caries.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"300-312"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147638230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functional evaluation of iPS cell-derived periodontal ligament-like cells. iPS细胞衍生的牙周韧带样细胞的功能评价。
IF 1.8 4区 医学
Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-03-25 DOI: 10.4012/dmj.2025-235
Haoqian Li, Kengo Iwasaki, Yufan Wu, Yoshiya Hashimoto, Aki Nishiura
{"title":"Functional evaluation of iPS cell-derived periodontal ligament-like cells.","authors":"Haoqian Li, Kengo Iwasaki, Yufan Wu, Yoshiya Hashimoto, Aki Nishiura","doi":"10.4012/dmj.2025-235","DOIUrl":"10.4012/dmj.2025-235","url":null,"abstract":"<p><p>Periodontal ligament (PDL) is essential in supporting tooth, remodeling, and regeneration of periodontal tissues; however, donor-derived PDL cells have limited regenerative applications. We previously developed a method to generate PDL-like cells from induced pluripotent stem (iPS) cells using PDL-conditioned medium. In this study, we validated whether iPS-derived PDL cells (iPS-PDL) recapitulate established functions of PDL cells. Morphologically, iPS-PDL resembled primary PDL cells and exhibited a higher proliferative capacity. They expressed PDL-related genes, such as Periostin, Asporin, and Tenascin-C, at levels exceeding those of fibroblasts. Under osteogenic induction, iPS-PDL deposited a mineralized matrix and upregulated the expression of COL1A1, ALPL, OCN, and RUNX2. Ascorbic acid enhanced ALP activity and collagen synthesis, while compressive force induced IL6, IL1β, and COX2 expression, These findings demonstrate that iPS-PDL retain PDL-like functions and are a promising cell source for periodontal regeneration, offering the potential for both therapeutic applications and in vitro modeling of periodontal biology.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"246-253"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147510247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of an MDP-containing cleaner on bonding of a self-adhesive resin composite to salivary-contaminated root dentin. 含mdp清洁剂对唾液污染的牙根质与自粘树脂复合材料粘接的影响。
IF 1.8 4区 医学
Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-04-22 DOI: 10.4012/dmj.2025-246
Shojiro Shimizu, Hanemi Tsuruta, Chiaki Okamoto, Riho Ito, Masaomi Ikeda, Michael F Burrow, Toru Nikaido, Katsushi Okuyama
{"title":"Effect of an MDP-containing cleaner on bonding of a self-adhesive resin composite to salivary-contaminated root dentin.","authors":"Shojiro Shimizu, Hanemi Tsuruta, Chiaki Okamoto, Riho Ito, Masaomi Ikeda, Michael F Burrow, Toru Nikaido, Katsushi Okuyama","doi":"10.4012/dmj.2025-246","DOIUrl":"10.4012/dmj.2025-246","url":null,"abstract":"<p><p>This study evaluated the effect of an MDP-containing cleaner on the bond strength of a self-adhesive resin composite (SAR) to saliva-contaminated bovine root dentin. Dentin surfaces were ground with #600 SiC and contaminated with artificial saliva for 20 s. Specimens were divided into four groups: water rinse (WA), 10% citric acid-3% ferric chloride solution (10-3), MDP-containing cleaner (KC), and non-contaminated (NC). SAR was applied according to the manufacturer's instructions. After 24 h of water storage at 37°C, μTBS was measured (n=10). KC showed no significant difference in μTBS compared with the NC (p>0.05), while no measurable bond strength was obtained for the WA and 10-3. Mixed failures comprising cohesive failure within dentin, cohesive failure within resin, and adhesive failure at the dentin-resin interface were more frequent in the NC. KC effectively removed contaminants and restored bonding performance. This method offers a promising restorative protocol for challenging clinical settings.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"293-299"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147765270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of voltage reduction on changes of shear bond strength and fracture mode of resin-modified glass-ionomer cements after current application. 电压降低对树脂改性玻璃离聚体水泥抗剪粘结强度和断裂方式变化的影响
IF 1.8 4区 医学
Dental materials journal Pub Date : 2026-05-25 Epub Date: 2026-04-14 DOI: 10.4012/dmj.2025-312
Ryouhei Wada, Emi Takegawa-Uyama, Shinya Horiuchi, Kazumitsu Sekine, Eiji Tanaka, Kenichi Hamada
{"title":"Effects of voltage reduction on changes of shear bond strength and fracture mode of resin-modified glass-ionomer cements after current application.","authors":"Ryouhei Wada, Emi Takegawa-Uyama, Shinya Horiuchi, Kazumitsu Sekine, Eiji Tanaka, Kenichi Hamada","doi":"10.4012/dmj.2025-312","DOIUrl":"10.4012/dmj.2025-312","url":null,"abstract":"<p><p>The enhanced bonding performance of dental cements is a clinical challenge, resulting in tooth damage because of excessive adhesion. Consequently, novel smart dental cements capable of on-demand bond strength reduction upon the application of an electrical current (CA) have been developed. Notably, a significant reduction in the shear bond strength (σ<sub>s</sub>) of resin-modified glass-ionomer cements (RMGICs) has been reported after the application of a 19 V CA for 30 s. However, this high voltage can damage the soft tissue and dental pulp. Therefore, we investigated whether comparable debonding performance could be achieved at lower voltages. The results showed a significant reduction in σ<sub>s</sub>. Importantly, debonding effects equivalent to those obtained with the 19 V condition were achieved at substantially lower voltages of 10-12 V. These findings indicate that reducing the applied voltage can maintain debonding performance while minimizing excessive electrical stimulation during current application.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"284-292"},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147688727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the biocompatibility and discoloration potential of a novel radiopaque Portland cement formulation for dental application. 一种新型牙科用不透光硅酸盐水泥配方的生物相容性和变色潜力评价。
IF 1.8 4区 医学
Dental materials journal Pub Date : 2026-03-29 Epub Date: 2026-01-10 DOI: 10.4012/dmj.2025-183
Hoda Mohamed Elnawawy, Muralithran Govindan Kutty, Noor Azlin Yahya, Noor Hayaty Abu Kasim, Paul Roy Cooper, Josette Camilleri, Hany Mohamed Aly Ahmed
{"title":"Evaluation of the biocompatibility and discoloration potential of a novel radiopaque Portland cement formulation for dental application.","authors":"Hoda Mohamed Elnawawy, Muralithran Govindan Kutty, Noor Azlin Yahya, Noor Hayaty Abu Kasim, Paul Roy Cooper, Josette Camilleri, Hany Mohamed Aly Ahmed","doi":"10.4012/dmj.2025-183","DOIUrl":"10.4012/dmj.2025-183","url":null,"abstract":"<p><p>This study compared the biocompatibility and discoloration potential of Malaysian Portland cement (MPC), experimental MPC (EPC), radiopaque nano-zirconium oxide modified EPC (REPC), with ProRoot white mineral trioxide aggregate (WMTA) using human dental pulp stem cells (HDPSCs) with/without lipopolysaccharide (LPS). Cytotoxicity and cell attachment were evaluated using MTT assay and scanning electron microscope (SEM) after 24/72 h. For discoloration, the cements were placed in extracted human permanent maxillary incisors and color was measured spectrophotometrically. Results showed that all extracts except 100 mg/mL were non-cytotoxic. For LPS-treated groups (24 h), WMTA demonstrated higher cell viability than REPC (p<0.008). At 72 h, all groups were comparable. At 24 h, LPS-treated HDPSCs exhibited lower values than untreated HDPSCs (p<0.008). At 72 h, differences were comparable. SEM demonstrated favorable HDPSCs attachment. Tooth discoloration was the highest for WMTA, and lowest for REPC. In conclusion, the biological properties of REPC were comparable with WMTA. REPC did not cause tooth discoloration.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"131-143"},"PeriodicalIF":1.8,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145958918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Remineralization efficacy of nano-hydroxyapatite and potassium nitrate formulations on demineralized enamel and dentin: An in vitro surface hardness and EDX-SEM study. 纳米羟基磷灰石和硝酸钾制剂对脱矿牙釉质和牙本质的再矿化效果：体外表面硬度和EDX-SEM研究。
IF 1.8 4区 医学
Dental materials journal Pub Date : 2026-03-29 Epub Date: 2026-03-05 DOI: 10.4012/dmj.2025-144
İdil Gönüllü, Elif Ercan Devrimci, Hande Kemaloğlu, Cem Peşkersoy, Murat Türkün
{"title":"Remineralization efficacy of nano-hydroxyapatite and potassium nitrate formulations on demineralized enamel and dentin: An in vitro surface hardness and EDX-SEM study.","authors":"İdil Gönüllü, Elif Ercan Devrimci, Hande Kemaloğlu, Cem Peşkersoy, Murat Türkün","doi":"10.4012/dmj.2025-144","DOIUrl":"10.4012/dmj.2025-144","url":null,"abstract":"<p><p>The present in vitro study aims to evaluate both the remineralizing and desensitizing potential of experimental dentifrices combining 2.5% and 5% nano-hydroxyapatite (nHAp) with 5% potassium nitrate. Twenty-four caries-free human teeth were prepared, and surface microhardness was measured before and after 96 h of demineralization. The gels were applied twice daily for 7 days, followed by post-treatment hardness assessment. Elemental composition (Ca, P, K, Ca/P ratio) was analyzed using energy-dispersive X-ray spectroscopy (EDX), and surface morphology was examined via scanning electron microscopy (SEM). Demineralization significantly reduced hardness and mineral ratios (p<0.05). Both formulations improved hardness and partially restored mineral levels. Including tests conducted within this study, dentin exhibited complete recovery, while enamel showed partial recovery. No statistically significant difference was found between the 2.5% and 5% nHAp concentrations. These findings suggest that both concentrations are effective, and increasing nHAp beyond 2.5% does not yield additional benefit, supporting their use as dual-action agents for remineralization and hypersensitivity relief.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":" ","pages":"169-176"},"PeriodicalIF":1.8,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147354165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书