A low-toxicity ammonium hydrogen fluoride-based etchant for bonding pretreatment of silica-based CAD-CAM materials.

IF 1.9 4区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Dental materials journal Pub Date : 2026-04-29 DOI:10.4012/dmj.2025-323

Ayako Miura, Yuya Komagata, Yuki Nagamatsu, Chihiro Masaki, Hiroshi Ikeda

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引用次数: 0

Abstract

This study aimed to develop a low-toxicity etchant for bonding pretreatment of silica-based CAD-CAM materials. An experimental etchant was prepared by combining ammonium hydrogen fluoride (AHF) with ammonium hydrogen sulfate (AHS) and subsequently optimized. The optimized AHF/AHS etchant was evaluated on lithium disilicate glass, feldspathic porcelain, polymer-infiltrated ceramic network, and resin composite, and compared with hydrofluoric acid (HF), a commercial etchant (Monobond Etch & Prime; MEP), and alumina sandblasting. For lithium disilicate glass, shear bond strength (SBS) obtained with AHF/AHS treatment was higher than that with MEP but lower than that with HF. For feldspathic porcelain and polymer-infiltrated ceramic network, SBS obtained with AHF/AHS was comparable to those obtained with HF. For resin composite, SBS obtained with AHF/AHS was higher than that with untreated control while lower than that with sandblasting. Cytotoxicity evaluated using human gingival fibroblasts showed IC₅₀ values comparable to those of phosphoric acid and sodium fluoride.

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一种用于硅基CAD-CAM材料粘接预处理的低毒氟化氢铵基蚀刻剂。

本研究旨在开发一种低毒性蚀刻剂，用于硅基CAD-CAM材料的粘合预处理。以氟化氢铵（AHF）和硫酸氢铵（AHS）为原料制备了一种实验性蚀刻剂，并对其进行了优化。优化后的AHF/AHS蚀刻剂在二硅酸锂玻璃、长石瓷、聚合物渗透陶瓷网络和树脂复合材料上进行了评价，并与氢氟酸（HF）、商业蚀刻剂（Monobond Etch & Prime； MEP）和氧化铝喷砂进行了比较。对于二硅酸锂玻璃，AHF/AHS处理获得的剪切粘接强度（SBS）高于MEP处理，但低于HF处理。对于长石瓷和聚合物浸润陶瓷网络，AHF/AHS获得的SBS与HF获得的SBS相当。对于树脂复合材料，AHF/AHS处理获得的SBS高于未处理对照，而低于喷砂处理。使用人类牙龈成纤维细胞进行的细胞毒性评估显示IC50值与磷酸和氟化钠相当。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dental materials journal 医学-材料科学：生物材料

CiteScore

4.60

自引率

4.00%

发文量

102

审稿时长

3 months

期刊介绍： Dental Materials Journal is a peer review journal published by the Japanese Society for Dental Materials and Devises aiming to introduce the progress of the basic and applied sciences in dental materials and biomaterials. The dental materials-related clinical science and instrumental technologies are also within the scope of this journal. The materials dealt include synthetic polymers, ceramics, metals and tissue-derived biomaterials. Forefront dental materials and biomaterials used in developing filed, such as tissue engineering, bioengineering and artificial intelligence, are positively considered for the review as well. Recent acceptance rate of the submitted manuscript in the journal is around 30%.