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Effects of canary seed on two patients with disseminated granuloma annulare. 金丝雀籽治疗弥散性肉芽肿2例疗效观察。
IF 1.1
Dermatology Reports Pub Date : 2023-06-07 DOI: 10.4081/dr.2023.9614
Lily Park, Claudia Green, Sergey Arutyunyan, Gabriella Vasile, Christopher Buckley, Eduardo Weiss
{"title":"Effects of canary seed on two patients with disseminated granuloma annulare.","authors":"Lily Park,&nbsp;Claudia Green,&nbsp;Sergey Arutyunyan,&nbsp;Gabriella Vasile,&nbsp;Christopher Buckley,&nbsp;Eduardo Weiss","doi":"10.4081/dr.2023.9614","DOIUrl":"https://doi.org/10.4081/dr.2023.9614","url":null,"abstract":"<p><p>Treatment of disseminated granuloma annulare (GA) can be challenging and there is no gold standard for treatment. We observed two cases of generalized GA that were treated successfully with canary seed milk despite being resistant to other treatments. Canary seed milk has antioxidant (contains vitamin E), anti-diabetic (DPP-4 inhibition), and anti-hypertensive (ACE inhibition) properties. Therefore, dermatologists can consider canary seed milk, also known as alpiste milk, as a sole or supplemental treatment for patients with GA with or without comorbidities such as diabetes and hypertension, who prefer alternative therapy or failed other treatments.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 2","pages":"9614"},"PeriodicalIF":1.1,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/47/9a/dr-15-2-9614.PMC10312104.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10122335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical, dermoscopic, and histopathologic findings of hidroacanthoma simplex: a case report and literature review. 单纯性汗腺瘤的临床、皮肤镜及组织病理学表现:1例报告及文献复习。
IF 1.1
Dermatology Reports Pub Date : 2023-06-07 DOI: 10.4081/dr.2022.9571
Maria Clara Almeida Issa, Carolina Airão Destefani, Alice Guiotti de Alencar, Mayra Carrijo Rochael, Maria Claudia Almeida Issa
{"title":"Clinical, dermoscopic, and histopathologic findings of hidroacanthoma simplex: a case report and literature review.","authors":"Maria Clara Almeida Issa,&nbsp;Carolina Airão Destefani,&nbsp;Alice Guiotti de Alencar,&nbsp;Mayra Carrijo Rochael,&nbsp;Maria Claudia Almeida Issa","doi":"10.4081/dr.2022.9571","DOIUrl":"https://doi.org/10.4081/dr.2022.9571","url":null,"abstract":"<p><p>Hidroacanthoma simplex (HS) is a rare benign intraepidermal tumor that originates in the acrosyringial portion of the eccrine duct. Clinically, they are well-defined lesions, flat or verrucous brownish plaque, and can be misdiagnosed with other types of benign or malignant tumors. Dermoscopy reveals small black globules and fine scales. The histopathology of HS is characterized by typical intraepidermal nests, well-circumscribed, composed of uniform basaloid and poroid cells within the acanthotic epidermis with cystic or ductal structures in the nests. We report a case of HS that changes its clinical appearance, dermoscopy, and histopathologic findings over time. Differential diagnoses included seborrheic keratosis, Bowen disease, melanoma, and malignant HS.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 2","pages":"9571"},"PeriodicalIF":1.1,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b7/68/dr-15-2-9571.PMC10327661.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9866266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rituximab for linear immunoglobulin A bullous dermatosis. 利妥昔单抗治疗线性免疫球蛋白A大疱性皮肤病。
IF 1.1
Dermatology Reports Pub Date : 2023-06-07 DOI: 10.4081/dr.2023.9574
Rummit Dhillon, Lily Park, Sarah Gabros, Tam Nguyen, Stanley Skopit
{"title":"Rituximab for linear immunoglobulin A bullous dermatosis.","authors":"Rummit Dhillon,&nbsp;Lily Park,&nbsp;Sarah Gabros,&nbsp;Tam Nguyen,&nbsp;Stanley Skopit","doi":"10.4081/dr.2023.9574","DOIUrl":"https://doi.org/10.4081/dr.2023.9574","url":null,"abstract":"<p><p>Linear immunoglobulin A bullous dermatosis (LABD) is an idiopathic or drug-induced vesiculobullous disease typically managed with dapsone or colchicine. We report a case of LABD successfully treated with rituximab in a patient who was intolerant to first-line therapies and recalcitrant to typical immunosuppressants. The patient was initially started on prednisone and mycophenolate mofetil which resulted in minimal response and disease progression. Improvement was seen after two infusions of rituximab 1000 mg at 2 weeks apart with planned maintenance therapy.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 2","pages":"9574"},"PeriodicalIF":1.1,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/df/95/dr-15-2-9574.PMC10327659.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9866269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An unusual case of Escherichia coli cellulitis and bacteremia in an immunocompetent patient. 一个不寻常的情况下，大肠杆菌蜂窝织炎和菌血症在免疫正常的病人。
IF 1.1
Dermatology Reports Pub Date : 2023-06-07 DOI: 10.4081/dr.2023.9603
Jacqueline K Nguyen, Eklid Hoxhallari, John Daffy
{"title":"An unusual case of <i>Escherichia coli</i> cellulitis and bacteremia in an immunocompetent patient.","authors":"Jacqueline K Nguyen,&nbsp;Eklid Hoxhallari,&nbsp;John Daffy","doi":"10.4081/dr.2023.9603","DOIUrl":"https://doi.org/10.4081/dr.2023.9603","url":null,"abstract":"<p><p>Cellulitis secondary to <i>Escherichia coli (E. coli)</i> is a rare phenomenon, particularly in an immunocompetent patient. We report an unusual case of an immunocompetent 84-year-old female presenting with <i>E.coli</i> bacteremia and <i>E. coli</i> cellulitis in the right lower leg. We postulate that bacterial translocation from the gastrointestinal tract to the bloodstream is the most likely source of <i>E. coli</i> infection. Whilst a common condition, cellulitis can pose a diagnostic and therapeutic challenge when a causative organism is not identified. Thorough investigation and consideration of atypical organisms such as <i>E.coli</i> are essential to permit targeted antimicrobial therapy and prevent patient deterioration.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 2","pages":"9603"},"PeriodicalIF":1.1,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a4/fe/dr-15-2-9603.PMC10327666.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9866268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment? 慢性肉芽肿病和痤疮一例:异维甲酸是一种安全的治疗方法吗?
IF 1.1
Dermatology Reports Pub Date : 2023-06-07 DOI: 10.4081/dr.2023.9631
Marco Brusasco, Claudio Feliciani, Maria Beatrice de Felici Del Giudice
{"title":"A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?","authors":"Marco Brusasco,&nbsp;Claudio Feliciani,&nbsp;Maria Beatrice de Felici Del Giudice","doi":"10.4081/dr.2023.9631","DOIUrl":"https://doi.org/10.4081/dr.2023.9631","url":null,"abstract":"<p><p>We report the case of a patient with chronic granulomatous disease and acne treated with isotretinoin, who developed a diffuse staphylococcal skin infection during the therapy. Chronic granulomatous disease is a rare genetic disorder characterized by an altered innate immunity with an increased risk of potentially lethal bacterial and fungal infections. Although chronic granulomatous disease is rare, acne is a common manifestation in these patients, but there are no data about the gold standard therapy.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 2","pages":"9631"},"PeriodicalIF":1.1,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b3/a3/dr-15-2-9631.PMC10327657.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9811937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autoinflammatory diseases: what is behind them and what is new? 自身炎症性疾病:背后是什么，有什么新的?
IF 1.1
Dermatology Reports Pub Date : 2023-06-07 DOI: 10.4081/dr.2023.9625
Michele Maalouly, Serena Saade, Mazen Kurban
{"title":"Autoinflammatory diseases: what is behind them and what is new?","authors":"Michele Maalouly,&nbsp;Serena Saade,&nbsp;Mazen Kurban","doi":"10.4081/dr.2023.9625","DOIUrl":"https://doi.org/10.4081/dr.2023.9625","url":null,"abstract":"<p><p>Autoinflammatory diseases are characterized by bouts of systemic or localized inflammation in the absence of an infection. While some autoinflammatory diseases are caused by a single gene mutation, others have been shown to be multifactorial, involving a large array of genes coupled with environmental factors. Previous studies briefly elucidated the molecular mechanisms behind the many autoinflammatory diseases, focusing on the dysregulation of interleukin (IL)-1β or IL-18, nuclear factor- κB activation, and Interferons secretion. In this review, we precisely highlight the autoinflammatory disease-specific signalosomes, and we aim to provide a scaffold of the link between the various affected pathways.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 2","pages":"9625"},"PeriodicalIF":1.1,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f1/12/dr-15-2-9625.PMC10327674.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9811944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lenvatinib-induced severe generalized erythematous rash in a patient with hepatocellular carcinoma. lenvatinib引起的肝细胞癌患者的严重全身性红斑皮疹。
IF 1.1
Dermatology Reports Pub Date : 2023-06-07 DOI: 10.4081/dr.2023.9617
Yukari Matsumoto, Takeshi Fukumoto, Wakako Takahashi, Chikako Nishigori
{"title":"Lenvatinib-induced severe generalized erythematous rash in a patient with hepatocellular carcinoma.","authors":"Yukari Matsumoto,&nbsp;Takeshi Fukumoto,&nbsp;Wakako Takahashi,&nbsp;Chikako Nishigori","doi":"10.4081/dr.2023.9617","DOIUrl":"https://doi.org/10.4081/dr.2023.9617","url":null,"abstract":"Lenvatinib, an oral multikinase inhibitor, is a first-line drug for the treatment of unresectable hepatocellular carcinoma. Here, we report a case of a 72-year-old man who presented with severe generalized erythematous rash (GER) approximately four weeks after the commencement of lenvatinib treatment, which he had been receiving for the treatment of unresectable lung metastases stemming from hepatocellular carcinoma. The patient had suffered from ichthyosis since his childhood, which made the diagnosis difficult. He had been diagnosed with dermatomycosis of the skin of whole body and treated by terbinafine tablets and luliconazole cream at another hospital. After remission of GER, lenvatinib was readministered because the patient’s metastatic lung tumor enlarged, which led to a recurrence of erythema with pruritus on the upper part of patient’s body. We confirmed the diagnosis of Lenvatinib-induced generalized GER based on the positive result of the patch test after the informed consent. To the best of our knowledge, this is the first detailed case of lenvatinibinduced GER. Raising physicians’ awareness of this potentially severe adverse effect is of importance because of lenvatinib’s increasing prominence as the drug of choice in cancer therapy.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 2","pages":"9617"},"PeriodicalIF":1.1,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/15/03/dr-15-2-9617.PMC10327660.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9866267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Use of a rhombic transposition flap in mandibular dermatosurgery. 菱形转位皮瓣在下颌骨皮肤手术中的应用。
IF 1.1
Dermatology Reports Pub Date : 2023-06-07 DOI: 10.4081/dr.2022.9672
Laura Miccio
{"title":"Use of a rhombic transposition flap in mandibular dermatosurgery.","authors":"Laura Miccio","doi":"10.4081/dr.2022.9672","DOIUrl":"https://doi.org/10.4081/dr.2022.9672","url":null,"abstract":"","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 2","pages":"9672"},"PeriodicalIF":1.1,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b2/a6/dr-15-2-9672.PMC10327665.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10168720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
En coup de sabre morphea: an uncommon condition in Africa. 在非洲，一种罕见的疾病。
IF 1.1
Dermatology Reports Pub Date : 2023-06-07 DOI: 10.4081/dr.2022.9537
Lehlohonolo Makhakhe, Ncoza Dlova, Annette Smith, Michelle du Preez
{"title":"<i>En coup de sabre</i> morphea: an uncommon condition in Africa.","authors":"Lehlohonolo Makhakhe,&nbsp;Ncoza Dlova,&nbsp;Annette Smith,&nbsp;Michelle du Preez","doi":"10.4081/dr.2022.9537","DOIUrl":"https://doi.org/10.4081/dr.2022.9537","url":null,"abstract":"<p><p>The term <i>en coup de sabre</i> morphea refers to a lesion of linear morphea typically located in the frontoparietal scalp and/or the paramedian forehead, often resembling a strike with a sword. In literature, <i>en coup de sabre</i> morphea, and <i>en coup de sabre</i> scleroderma are terms used interchangeably and synonymously. Due to the rarity of this condition, treatment is largely based on case report series, leaving much room for speculation in terms of drugs of choice, duration of treatment, and dosages. Although it typically leaves behind notable and often permanent skin pigmentary changes and indentation of the affected areas, this condition usually remits spontaneously, even in the absence of an active form of treatment. The disease severity and prognosis vary according to the subtype: circumscribed morphea has a generally more benign course when compared with linear scleroderma and generalized morphea.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 2","pages":"9537"},"PeriodicalIF":1.1,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6b/24/dr-15-2-9537.PMC10312106.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10122330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Generalized morphea induced by the COVID-19 vaccine in a patient with chronic urticaria. COVID-19疫苗致慢性荨麻疹患者全身性麻痹1例
IF 1.1
Dermatology Reports Pub Date : 2023-06-07 DOI: 10.4081/dr.2023.9632
Hend Alotaibi, Abdulaziz Alsalhi, Turki Albinhar, Yazeed Alshathry, Maha Barakeh
{"title":"Generalized morphea induced by the COVID-19 vaccine in a patient with chronic urticaria.","authors":"Hend Alotaibi,&nbsp;Abdulaziz Alsalhi,&nbsp;Turki Albinhar,&nbsp;Yazeed Alshathry,&nbsp;Maha Barakeh","doi":"10.4081/dr.2023.9632","DOIUrl":"https://doi.org/10.4081/dr.2023.9632","url":null,"abstract":"<p><p>Adverse events following vaccinations have been noted for centuries, but as of recently, discussions concerning these adverse effects have increased due to the COVID-19 pandemic and the consequent delivery of vaccinations. Through presenting new cases of such adverse events and reviewing the literature, we aim to facilitate the recognition of COVID-19 vaccine-induced autoimmune diseases that may occur in the years after the pandemic has been contained. We report on a case of biopsy-proven morphea after the COVID-19 vaccine, in which case the patient developed diffuse skin lesions all over her body. The patient was known to have chronic urticaria and received two doses of the Pfizer-BioNTech COVID-19 vaccines (BioNTech, Fosun Pharma, Pfizer, New York City, USA). The patient started to notice itchy lesions on her arms two months after taking her second dose of the vaccine. This is the first case reported of generalized morphea following COVID-19 vaccination with another autoimmune disease and represents the first case of generalized morphea reported in the Middle East.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 2","pages":"9632"},"PeriodicalIF":1.1,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/10/1b/dr-15-2-9632.PMC10312103.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10122333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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