Dermatology Reports最新文献

{"title":"Cross-sectional evaluation of TikTok video quality on alopecia areata.","authors":"Hilla Rosenberg, Chaya Bracha Gordon, Yael Hollander, Reut Rotem, Amir Horev","doi":"10.4081/dr.2026.10952","DOIUrl":"https://doi.org/10.4081/dr.2026.10952","url":null,"abstract":"<p><p>Alopecia areata (AA) is an autoimmune condition that results in hair loss, significantly impacting quality of life. As TikTok emerges as a major platform for health-related information, concerns about the spread of misinformation have arisen. This cross-sectional study aims to evaluate the quality, reliability, and understandability of \"most liked\" AA-related TikTok videos. Videos were categorized as healthcare providers (HP) or non-healthcare providers (NHP). Two reviewers independently assessed the videos, using validated tools - Patient Education Materials Assessment Tool for audiovisual content (PEMAT A/V), modified DISCERN (mDISCERN), Video Information and Quality Index (VIQI), Global Quality Scale (GQS), and AloCheck, a study-specific content-coverage tool. Among 93 included videos, only 26% were created by HPs, who scored significantly higher across all quality metrics: mDISCERN (3.0 vs. 1.5, p<0.01), GQS (3.5 vs. 1.5, p<0.01), VIQI (13.75 vs. 11.0, p<0.01), and PEMAT A/V (≥10: 66.7% vs. 26.1%, p<0.01). HPs focused on clinical aspects (87.5% vs. 40.6%, p<0.01), whereas NHPs emphasized psychological aspects, such as body image (37.5% vs. 63.8%, p=0.02). Findings reveal a gap between quality and user engagement, highlighting the risk that lower-quality information reaches a wide audience. Bridging this gap is essential to support the delivery of high-quality, reliable, and engaging health information to the public.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Why does classic scabies spare the adult scalp? A site-specific barrier hypothesis.","authors":"Caterina Mariarosaria Giorgio, Gaetano Licata, Giuseppe Argenziano","doi":"10.4081/dr.2026.10955","DOIUrl":"https://doi.org/10.4081/dr.2026.10955","url":null,"abstract":"<p><p>Dear Editor, The relative sparing of the scalp and face in immunocompetent adults with classic scabies is clinically familiar, whereas these sites may be involved in infants, older adults, immunocompromised patients, and crusted scabies. This distribution is commonly used as a diagnostic clue, but its biological basis remains incompletely explained. [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The reliability of clinical judgments in dermatology: a descriptive review on their role as a reference standard for technological diagnostic research.","authors":"Nelly Mwageni, Robin Van Wijk, Anne Schoenmarkers, John Elisante Masenga, Christa Kasang, Liesbeth Mieras, Stephen E Mshana","doi":"10.4081/dr.2026.10064","DOIUrl":"https://doi.org/10.4081/dr.2026.10064","url":null,"abstract":"<p><p>The expansion of dermatological mobile health (mHealth) and teledermatology has generated numerous diagnostic support tools, typically validated against traditional face-to-face assessments. Histopathological confirmation through skin biopsy is invasive, resource-intensive and, in many African settings, not readily available as a dermatological research reference standard. Yet, the reliability of clinical diagnoses used as such standards remains uncertain. The study objective was to assess the consistency (inter-rater reliability) of face-to-face clinical judgments among multiple dermatologists evaluating the same patient group. For this descriptive literature review, a comprehensive search of seven databases and information platforms was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guideline. In total, 1,700 studies were found after deduplication and screened using pre-set criteria. Eighteen studies were included: three compared clinical diagnoses directly and 15 assessed the reliability of dermatological scoring systems for disease severity and activity. All studies involved two or more dermatologists assessing the same patients. Reported agreement among raters ranged from 0.15 to 0.98 for studies evaluating clinical diagnosis and from 0.07 to 0.95 for studies assessing disease severity or activity scores, demonstrating wide variability in inter-rater reliability. In conclusion, clinical diagnosis alone, especially if made by one or a limited number of dermatologists, may not provide a sufficiently reliable reference standard for validating teledermatology, dermatological mHealth applications, or artificial intelligence (AI) tools. Strengthening evidence on the reliability of diagnostic reference standards is essential for evaluating emerging digital health innovations, particularly in regions with limited access to dermatologists and histopathology services. Future studies, with similarly experienced dermatological assessors, should have larger sample sizes, assess diagnostic agreement rather than disease severity outcomes, combine inter- and intra-rater assessments, and include diverse geographic contexts such as Africa, Asia and Latin America. The potential influence of assessors' levels of experience on agreement should also be explored. A final recommendation is to come to a consensus about skin color classification.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149191955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary anetoderma as a possible preclinical cutaneous clue of Behçet's disease: evidence suggesting early microvascular-driven dermal elastolysis.","authors":"Pasquale Sorrentino, Maria Maddalena Nicoletti, Margherita Malaspina, Gaetano Licata, Stefano Lucà, Eugenia Veronica Di Brizzi, Giuseppe Argenziano, Caterina Mariarosaria Giorgio","doi":"10.4081/dr.2026.10871","DOIUrl":"https://doi.org/10.4081/dr.2026.10871","url":null,"abstract":"<p><p>Anetoderma is a rare elastolytic dermatosis characterized by focal loss of dermal elastic fibers leading to localized flaccid, atrophic, or herniated skin lesions. Although it may occur as a primary disorder or secondary to inflammatory dermatoses, infections, or trauma, immune-mediated vascular injury and dysregulation of extracellular matrix remodeling are increasingly recognized as key pathogenetic mechanisms. Behçet's disease (BD) is a multisystem inflammatory vasculitis driven by neutrophil hyperactivation and endothelial dysfunction, but elastolytic dermatoses have not been included among its classical cutaneous manifestations. We report a 27-year-old man who developed multiple asymptomatic atrophic lesions on the trunk and upper back. Histopathologic examination revealed preserved epidermal architecture and marked loss of elastic fibers in the papillary and mid dermis on Verhoeff-Van Gieson staining, consistent with primary anetoderma. Approximately 3 years later, the patient developed recurrent oral aphthosis, genital ulcers, papulopustular lesions, and a positive pathergy test, fulfilling the International Criteria for Behçet's Disease. The temporal sequence observed in our patient raises the hypothesis that primary anetoderma may represent a rare early cutaneous manifestation or a preclinical marker of microvascular inflammation in BD. Neutrophil-driven proteolysis and increased matrix metalloproteinase (MMP) activity may contribute to focal dermal elastolysis. Further observations are needed to clarify whether this association reflects a pathogenetic link or a coincidental finding.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of red palm oil (<i>Elaeis guineensis</i> Jacq.) on skin hydration in streptozotocin-induced diabetic white rat models.","authors":"Ariyati Yosi, Putri Chairani Eyanoer, Ramona Dumasari Lubis, Muhammad Rusda, Irma Damayanti Roesyanto Mahadi","doi":"10.4081/dr.2026.10917","DOIUrl":"https://doi.org/10.4081/dr.2026.10917","url":null,"abstract":"<p><p>Diabetes mellitus (DM) is frequently associated with cutaneous complications, including xerosis cutis, due to impaired skin barrier function. Red palm oil (RPO; Elaeis guineensis Jacq.) contains bioactive compounds with antioxidant, anti-inflammatory, and barrier-repair properties that may improve skin hydration. The objective of this study was to evaluate the effect of topical RPO on skin hydration in streptozotocin (STZ)-induced diabetic rat models. Thirty-two male Sprague-Dawley rats were randomly assigned to four groups (n=8 each): normal control (G1), untreated diabetic (G2), diabetic treated with 10% urea cream (G3), and diabetic treated with RPO (G4). Diabetes was induced using STZ and confirmed by blood glucose measurement. Treatments were applied once daily for 28 days to a standardized dorsal skin area. Skin hydration was assessed using a Corneometer®. Data were analyzed using the Shapiro-Wilk test and one-way analysis of variance (ANOVA) followed by the Tukey post hoc test. Skin hydration differed significantly among groups (p<0.001). The highest mean hydration was observed in the normal group (34.13 arbitrary units [AU]), while the lowest was in untreated diabetic rats (14.38 AU). RPO treatment significantly increased skin hydration (29.00 AU) compared to untreated diabetic rats (p<0.001) and urea-treated rats (p<0.001). No significant difference was found between the RPO-treated and normal groups (p=0.082). To conclude, topical RPO significantly improves skin hydration in diabetic rats, with effects comparable to normal skin and superior to 10% urea cream. RPO shows potential as a therapeutic agent for diabetes-associated xerosis.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149126771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stigmatization in patients with chronic skin diseases in the Eastern Region of Saudi Arabia: a cross-sectional study.","authors":"Danah Sami Alali, Marwa Salman Aldehailan, Almaha Abdullah Alhijab, Tala Abdullah Alshamrani, Abdulelah Nabil Alkadi, Ajlan Hashim Alajlani, Sukaina Mohammad Al Haddad","doi":"10.4081/dr.2026.10913","DOIUrl":"https://doi.org/10.4081/dr.2026.10913","url":null,"abstract":"<p><p>Chronic skin diseases such as psoriasis, vitiligo, eczema, and acne can have substantial psychosocial effects beyond physical symptoms. Visible dermatological conditions often lead to stigmatization, which may negatively influence social interactions, emotional well-being, and quality of life. However, limited research has examined perceived stigmatization among patients with chronic skin diseases in the Eastern Province of Saudi Arabia. This study aimed to quantify and compare perceived stigmatization among patients with chronic skin diseases and identify demographic and clinical factors associated with stigma severity. A cross-sectional study was conducted among 446 patients with chronic skin diseases. Data were collected using a structured questionnaire, including sociodemographic characteristics, clinical information, and the 6-Item Stigmatization Scale. Descriptive statistics were used to summarize participant characteristics. Independent t-tests, one-way analysis of variance (ANOVA), and multivariable linear regression analysis were performed to examine associations between stigma scores and demographic and clinical variables. A total of 446 participants were included, with females comprising 264 (59.2%) and most aged 18-40 years (291, 65.2%). Vitiligo (114, 25.6%) and psoriasis (102, 22.9%) were the most common conditions. Many participants reported stigma-related experiences, including feeling unattractive sometimes or very often (326, 73.0%). Stigma scores were significantly higher among males than females (8.12±3.93 vs. 7.03±4.73, p=0.011) and varied by monthly income (p<0.001). Stigma also differed across disease types (p<0.001), with the highest scores among vitiligo patients (8.74±3.98). In regression analysis, gender (B=1.039, p=0.016), age at disease onset (B=0.052, p=0.002), disease duration (B=-1.268, p=0.003), and family history (B=1.825, p<0.001) were significant predictors of stigma. To conclude, stigmatization is a common psychosocial burden among patients with chronic skin diseases. Addressing stigma through patient support, public education, and integrated psychological care may help improve the well-being of affected individuals.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149126731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anxiety, patient satisfaction, and outcomes of intense pulsed light-based treatment for moderate-to-severe acne vulgaris in Southern Vietnam.","authors":"Thi Xuan Tam Huynh, Thi Yen Ba Nguyen, Tuyet Tam Tu","doi":"10.4081/dr.2026.10943","DOIUrl":"https://doi.org/10.4081/dr.2026.10943","url":null,"abstract":"<p><p>Acne vulgaris is a common inflammatory disorder with psychosocial consequences. Data on anxiety and outcomes of intense pulsed light (IPL)-based therapy for moderate-to-severe acne remain limited in Vietnam. This study described clinical characteristics, anxiety burden, satisfaction, and treatment outcomes after IPL-based management. A single-center study was conducted at Can Tho Dermatology Hospital (Vietnam) from May 2023 to May 2024. A total of 220 patients aged ≥12 years with moderate-to-severe acne vulgaris were enrolled. Acne severity was evaluated using the Global Acne Grading System (GAGS), while anxiety was assessed using the anxiety subscale of the Depression Anxiety Stress Scales-21 (DASS-21). Thirty-six patients with anxiety underwent an 8-week IPL-based combination regimen. Clinical response, GAGS score, anxiety change, satisfaction, and tolerability were evaluated. The mean age was 21.8±6.3 years, and 59.5% were female. Papulopustular acne was predominant (98.6%), and all patients had facial involvement. Post-inflammatory hyperpigmentation and atrophic scarring were present in 100.0% and 76.8%, respectively. Baseline anxiety was identified in 48.6% of patients. Severe acne was strongly associated with anxiety compared with moderate acne (odds ratio [OR]=24.64; 95% confidence interval [CI]: 7.32-127.43; p<0.001). In the treatment subgroup, good clinical response increased from 36.1% at week 4 to 66.7% at week 8. Mean GAGS score decreased from 25.3±3.8 to 12.7±5.9 (p<0.001), and treatment success reached 86.1%. Anxiety decreased from 100.0% to 30.6% after treatment (p<0.001). Most patients were satisfied (86.1%), and adverse effects were mild. Moderate-to-severe acne was frequently associated with anxiety. An IPL-based regimen was associated with clinical improvement, reduced anxiety, high satisfaction, and good tolerability.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149105604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When the fat is missing: a fat-free spindle cell lipoma in a young woman.","authors":"Maria Elisabetta Greco, Kiran Javaid, Shaunt Mehdikhani, Izadora Lapenda, Dan Rolando Lopez, Madeline Tchack, Bassem Rafiq, Noah Musolff, Babar Rao","doi":"10.4081/dr.2026.10840","DOIUrl":"https://doi.org/10.4081/dr.2026.10840","url":null,"abstract":"<p><p>Dear Editor, Spindle cell lipoma (SCL) is a benign adipocytic neoplasm first characterized by Enzinger and Harvey, classically arising in the posterior neck, shoulder, and upper back of middle-aged to older men. Histologically, it is defined by a variable admixture of mature adipocytes, bland spindle cells, rope-like collagen, and myxoid matrix. The adipocytic component, however, may be minimal or entirely absent, creating a diagnostically deceptive low-fat or fat-free phenotype. [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149105570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barber-related tinea infections: a hidden public health risk in the era of electric grooming.","authors":"Caterina Mariarosaria Giorgio, Margherita Malaspina, Maria Maddalena Nicoletti, Cesare Ariasi, Mariachiara Arisi, Giuseppe Argenziano, Gaetano Licata","doi":"10.4081/dr.2026.10533","DOIUrl":"https://doi.org/10.4081/dr.2026.10533","url":null,"abstract":"<p><p>Dear Editor, In recent years, dermatologists across multiple countries have observed a resurgence of superficial dermatophytoses, particularly among adolescents and young adults. This epidemiological shift has been attributed to changing grooming habits, including the widespread use of electric razors and trimmers in commercial barbershops. [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149105606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatosurgical rounds: <i>Schwenklappenplastik</i> (nasolabial transposition flap) with transposition from the neighboring area in a patient with high-risk basal cell carcinoma in the ala nasi.","authors":"Georgi Tchernev, Konstantin Georgiev Tchernev, Simona Kordeva","doi":"10.4081/dr.2026.10988","DOIUrl":"https://doi.org/10.4081/dr.2026.10988","url":null,"abstract":"<p><p>A 72-year-old male presented to the dermatology department with a primary complaint of a tumorous formation, measuring 1.2×1.2 cm, protruding above the surrounding skin, with central ulceration and covered by a hemorrhagic crust. The lesion was located across multiple cosmetic subunits of the nasal ala, involving the left alar lobule and the inferior part of the left lateral nasal sidewall. Based on the clinical presentation, nodular basal cell carcinoma was suspected and surgical excision under local anesthesia was recommended. [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149105519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}