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Comparative analysis of Curcuma longa (curcumin) and fusidic acid on the antimicrobial susceptibility of Staphylococcus aureus and Streptococcus pyogenes in impetigo. 姜黄素与夫西地酸对脓疱疮金黄色葡萄球菌和化脓性链球菌的药敏比较分析。
IF 1.3
Dermatology Reports Pub Date : 2026-05-08 DOI: 10.4081/dr.2026.10339
Fifa Argentina, Nopriyati Nopriyati, Riri Puspa Putri Findrapase, Hasbiallah Yusuf, Monica Trifitriana, Debby Handayati Harahap
{"title":"Comparative analysis of <i>Curcuma longa</i> (curcumin) and fusidic acid on the antimicrobial susceptibility of <i>Staphylococcus aureus</i> and <i>Streptococcus pyogenes</i> in impetigo.","authors":"Fifa Argentina, Nopriyati Nopriyati, Riri Puspa Putri Findrapase, Hasbiallah Yusuf, Monica Trifitriana, Debby Handayati Harahap","doi":"10.4081/dr.2026.10339","DOIUrl":"https://doi.org/10.4081/dr.2026.10339","url":null,"abstract":"<p><p>Impetigo is a bacterial skin infection primarily caused by Staphylococcus aureus or Streptococcus pyogenes. Curcuma longa contains curcumin, known for its antibacterial, anti-inflammatory, and antioxidant properties. Evaluating the susceptibility of these bacteria to C. longa extract can help assess its potential as an antimicrobial agent. This study aimed to determine the susceptibility of S. aureus and S. pyogenes to C. longa extract and fusidic acid in impetigo patients. An in vitro experimental study using a posttest-only control group design was conducted from August to October 2023. Bacterial isolates were obtained from 60 impetigo patients (30 S. aureus and 30 S. pyogenes isolates). The isolates were treated with fusidic acid discs and C. longa extracts at 20%, 40%, and 80%. Inhibition zone diameters were measured and analyzed using the disc diffusion method and SPSS 25.0. The mean inhibition zone for S. aureus was 10.62 mm (20%), 11.78 mm (40%), and 16.21 mm (80%). For S. pyogenes, it was 9.86 mm (20%), 10.99 mm (40%), and 14.91 mm (80%). The Mann-Whitney test found no significant difference in inhibition between fusidic acid 10 μg and C. longa 40% or 80% (p≥0.05). Kruskal-Wallis analysis showed significant differences across treatment groups (p=0.000). C. longa, 40% and 80%, showed comparable antimicrobial activity to fusidic acid, indicating its potential as an alternative treatment for impetigo.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Omalizumab for treatment of refractory urticaria in a patient with metastatic uveal melanoma receiving tebentafusp. 奥玛珠单抗治疗转移性葡萄膜黑色素瘤患者的难治性荨麻疹。
IF 1.3
Dermatology Reports Pub Date : 2026-05-06 DOI: 10.4081/dr.2026.10366
Faith Simmonds, Veronica Kashua, Diana McDonnell, Mariam El-Ashmawy, Alexandra J Coromilas
{"title":"Omalizumab for treatment of refractory urticaria in a patient with metastatic uveal melanoma receiving tebentafusp.","authors":"Faith Simmonds, Veronica Kashua, Diana McDonnell, Mariam El-Ashmawy, Alexandra J Coromilas","doi":"10.4081/dr.2026.10366","DOIUrl":"https://doi.org/10.4081/dr.2026.10366","url":null,"abstract":"<p><p>Tebentafusp is an immune-mobilizing monoclonal T-cell receptor approved for the treatment of metastatic uveal melanoma. While this agent improves outcomes in patients with unresectable or metastatic uveal melanoma, tebentafusp commonly results in dermatologic cutaneous toxicities. Herein, we present a case of a 32-year-old patient diagnosed with juxtapapillary choroidal melanoma of the left eye with metastases to the liver who developed a diffuse urticarial skin reaction to tebentafusp that was successfully treated with omalizumab.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Publication trends in vitiligo research from 1991 to 2024: a comprehensive bibliometric analysis. 1991年至2024年白癜风研究的出版趋势：综合文献计量分析。
IF 1.3
Dermatology Reports Pub Date : 2026-05-04 DOI: 10.4081/dr.2026.10656
Yuh-Shan Ho, Hilla Rosenberg, Jonathan Shapiro, Amir Horev
{"title":"Publication trends in vitiligo research from 1991 to 2024: a comprehensive bibliometric analysis.","authors":"Yuh-Shan Ho, Hilla Rosenberg, Jonathan Shapiro, Amir Horev","doi":"10.4081/dr.2026.10656","DOIUrl":"https://doi.org/10.4081/dr.2026.10656","url":null,"abstract":"<p><p>Over the last three decades, vitiligo research has expanded across clinical, genetic, and therapeutic domains. Accurate literature retrieval and bibliometric analysis are essential for identifying major themes and emerging topics within this field. A bibliometric analysis was conducted to identify vitiligo-related studies published between 1991 and 2024, using the Science Citation Index Expanded (SCIE) database. Using a \"front page\" strategy, articles containing \"vitiligo\" in the title, abstract, or author keywords were included. Extracted data encompassed titles, abstracts, and keywords to identify dominant research themes. Citation indicators, including total and annual citations, were used to assess impact and trends. Analyses were performed using Microsoft Excel 365. A total of 4,925 vitiligo articles were retrieved and divided into three periods: 1991-2010 (1,654); 2011-2018 (1,541); and 2019-2024 (1,730). The most frequent title word was \"patients\" (17%), while abstracts frequently included \"patients\" (63%), \"skin\" (46%), and \"treatment\" (41%). Prominent author keywords were \"melanocytes\", \"autoimmunity\", and a growing focus on \"epidemiology\". Increasing trends appeared for \"immunotherapy\" and \"oxidative stress\", while \"efficacy\", \"prevalence\", and \"polymorphism\" declined. Research is shifting toward molecular mechanisms and innovative therapies, offering guidance for future studies and improved disease understanding and management.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morbihan disease in an Asian patient: diagnostic and therapeutic challenges. 一位亚洲患者的Morbihan病：诊断和治疗的挑战。
IF 1.3
Dermatology Reports Pub Date : 2026-04-28 DOI: 10.4081/dr.2026.10487
Giulia Ciccarese, Riccardo Bortone, Alexandre Raphael Meduri, Benedetta Tirone, Francesco Drago, Caterina Foti, Gloria Hoxhallari, Domenico Bonamonte, Marco Bellino
{"title":"Morbihan disease in an Asian patient: diagnostic and therapeutic challenges.","authors":"Giulia Ciccarese, Riccardo Bortone, Alexandre Raphael Meduri, Benedetta Tirone, Francesco Drago, Caterina Foti, Gloria Hoxhallari, Domenico Bonamonte, Marco Bellino","doi":"10.4081/dr.2026.10487","DOIUrl":"https://doi.org/10.4081/dr.2026.10487","url":null,"abstract":"<p><p>Dear Editor, Morbihan disease (MD) is a rare condition affecting mainly middle-aged Caucasian adults, characterized by persistent swelling of the upper face. First described in 1956, it was named by Gorin et al. in 1991 after a French patient from the Morbihan region. The etiology remains unclear and is likely multifactorial, involving lymphatic drainage impairment and chronic vascular inflammation, supporting its association with rosacea. Histological findings parallel those of rosacea, characterized by perivascular and inflammatory infiltrates, dermal edema, and sebaceous gland hyperplasia. Diagnosis relies on clinical features and ruling out other conditions that look similar. [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147765190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of scleromyxedema Arndt-Gottron with a novel intravenous immunoglobulin preparation. 一种新型静脉注射免疫球蛋白制剂治疗硬黏液水肿。
IF 1.3
Dermatology Reports Pub Date : 2026-04-14 DOI: 10.4081/dr.2026.10557
Niklas Negele, Julia K Winkler, Alexander H Enk
{"title":"Treatment of scleromyxedema Arndt-Gottron with a novel intravenous immunoglobulin preparation.","authors":"Niklas Negele, Julia K Winkler, Alexander H Enk","doi":"10.4081/dr.2026.10557","DOIUrl":"https://doi.org/10.4081/dr.2026.10557","url":null,"abstract":"<p><p>Dear Editor, Scleromyxedema is known as a rare, severe mucinosis with characteristic waxy skin papules along with sclerodermiform induration of the skin and rare systemic manifestations. Monoclonal gammopathy of undetermined significance (MGUS; mostly monoclonal immunoglobulin G [IgG] type lambda) can be detected in up to 90% of patients. [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dermoscopic features of amelanotic cutaneous melanoma metastases: evidence from four cases. 皮肤无色素黑色素瘤转移的皮肤镜特征：来自4例的证据。
IF 1.3
Dermatology Reports Pub Date : 2026-04-07 DOI: 10.4081/dr.2026.10425
Marco Campoli, Chiara Barlusconi, Nicola Zerbinati, Maurizio Lombardo
{"title":"Dermoscopic features of amelanotic cutaneous melanoma metastases: evidence from four cases.","authors":"Marco Campoli, Chiara Barlusconi, Nicola Zerbinati, Maurizio Lombardo","doi":"10.4081/dr.2026.10425","DOIUrl":"https://doi.org/10.4081/dr.2026.10425","url":null,"abstract":"<p><p>Cutaneous metastases of malignant melanoma (MM) are relatively common, occurring in 2-20% of cases. These metastases typically present as pigmented papules or nodules but can occasionally manifest in unusual forms, such as amelanotic cutaneous melanoma metastases (ACMMs). Due to their relative rarity (less than one-third of cutaneous metastases of MM), definitive dermoscopic characterization of ACMMs remains elusive. This case series investigates the dermoscopic features of four ACMM cases, all of which exhibited vascular patterns. Consolidating our findings with existing literature, polymorphic vessels and linear irregular/serpentine vessels emerge as the predominant patterns in ACMMs. Notably, in one case, the primary melanoma was initially unrecognized, with metastases appearing as the initial manifestation of the disease. This series underscores the need to establish precise dermoscopic criteria for ACMMs.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147627460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A young case of digital papillary adenocarcinoma successfully treated by wide local excision. 年轻手指乳头状腺癌经广泛局部切除成功治疗1例。
IF 1.3
Dermatology Reports Pub Date : 2026-04-03 DOI: 10.4081/dr.2026.10646
Hideki Hachiken, Takeshi Fukumoto, Toshihiro Yagita, Makoto Kinusada, Akiharu Kubo
{"title":"A young case of digital papillary adenocarcinoma successfully treated by wide local excision.","authors":"Hideki Hachiken, Takeshi Fukumoto, Toshihiro Yagita, Makoto Kinusada, Akiharu Kubo","doi":"10.4081/dr.2026.10646","DOIUrl":"https://doi.org/10.4081/dr.2026.10646","url":null,"abstract":"<p><p>Dear Editor, Digital papillary adenocarcinoma (DPA) is a rare malignant tumor originating from the sweat glands, predominantly affecting the digits of middle-aged to elderly individuals, with a higher incidence in males. DPA presents as a painless, slow-growing nodule on the fingers or toes, often leading to delayed diagnosis. DPA is characterized by complex papillary and tubular structures, cytologic atypia, and frequent mitotic figures. Due to its propensity for local recurrence and distant metastasis, early detection and local excision with clear margins are crucial for effective management. Regular long-term follow-up is recommended to monitor for recurrence or metastasis. Here, we present a young case of DPA located on the hand successfully treated by wide local excision. [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147608153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mycoplasma pneumoniae-induced rash and mucositis: two case reports and literature review. 肺炎支原体引起的皮疹和粘膜炎：2例报告并文献复习。
IF 1.3
Dermatology Reports Pub Date : 2026-03-31 DOI: 10.4081/dr.2026.10336
Chiara Sabbadini, Irina Mariotti, Leonardo Tei, Walburga Cassar, Carla Nobile
{"title":"<i>Mycoplasma pneumoniae</i>-induced rash and mucositis: two case reports and literature review.","authors":"Chiara Sabbadini, Irina Mariotti, Leonardo Tei, Walburga Cassar, Carla Nobile","doi":"10.4081/dr.2026.10336","DOIUrl":"https://doi.org/10.4081/dr.2026.10336","url":null,"abstract":"<p><p>Mycoplasma pneumoniae is one of the most prevalent pathogens involved in respiratory infections. A new syndrome characterized by prominent mucositis and sparse cutaneous involvement related to the infection has recently been described. We report two clinical cases from our Dermatological Department.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147580769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atypical exanthem associated with human herpesvirus 7 active infection in a 24-year-old man. 1例24岁男性与人类疱疹病毒7型活动性感染相关的非典型外泄。
IF 1.3
Dermatology Reports Pub Date : 2026-03-30 DOI: 10.4081/dr.2026.10441
Francesco Drago, Giorgia Sbarra, Giovanni Liguori, William Andrew Rosato, Aurora De Marco, Lucia Lospalluti, Anna Maria Colacicco, Caterina Foti, Giulia Ciccarese
{"title":"Atypical exanthem associated with human herpesvirus 7 active infection in a 24-year-old man.","authors":"Francesco Drago, Giorgia Sbarra, Giovanni Liguori, William Andrew Rosato, Aurora De Marco, Lucia Lospalluti, Anna Maria Colacicco, Caterina Foti, Giulia Ciccarese","doi":"10.4081/dr.2026.10441","DOIUrl":"https://doi.org/10.4081/dr.2026.10441","url":null,"abstract":"<p><p>Dear Editor, An otherwise healthy 24-year-old male patient presented to us with a three-day history of a diffuse, pruritic skin eruption preceded by low-grade fever and fatigue in the previous two weeks. Physical examination revealed an atypical exanthem with a polymorphic pattern characterized by diffuse erythematous macular lesions on the forehead, erythema, edema, and vesicles on the ears, erythematous papules on the forearms and trunk, and maculo-papular-petechial lesions on the pubic area and buttocks. An erythematous-purpuric enanthem and symmetrical enlargement of the cervical-axillary lymph nodes were also detected. [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147580742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of hereditary hemorrhagic telangiectasia with ACVRL1 gene variant. 遗传性出血性毛细血管扩张伴ACVRL1基因变异1例。
IF 1.3
Dermatology Reports Pub Date : 2026-03-27 DOI: 10.4081/dr.2026.10582
Sawako Ochiai, Reimon Yamaguchi, Kiminobu Takeda, Naoto Oishi, Sumihito Togi, Hiroki Ura, Yo Niida, Akira Shimizu
{"title":"A case of hereditary hemorrhagic telangiectasia with <i>ACVRL1</i> gene variant.","authors":"Sawako Ochiai, Reimon Yamaguchi, Kiminobu Takeda, Naoto Oishi, Sumihito Togi, Hiroki Ura, Yo Niida, Akira Shimizu","doi":"10.4081/dr.2026.10582","DOIUrl":"https://doi.org/10.4081/dr.2026.10582","url":null,"abstract":"<p><p>Dear Editor, Hereditary hemorrhagic telangiectasia (HHT) is an inherited vascular disease characterized by multiple localized abnormal connections between an artery and a vein. The majority (>85%) of HHT patients are heterozygous for loss-of-function variants in the ENG (HHT1) or ACVRL1 (HHT2) genes, while a minority (<5%) carry pathogenic variants in the SMAD4 gene and show a combined juvenile polyposis and HHT phenotype (JP/HHT). In addition, a very rare group of patients with an HHT-like phenotype maps to variants in GDF2 (also known as BMP9, HHT5). [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147527345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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