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Scabies mimicking relapsing atopic dermatitis 模仿复发性特应性皮炎的疥疮
IF 2.3
Dermatology Reports Pub Date : 2024-08-09 DOI: 10.4081/dr.2024.10070
F. Pigliacelli, E. Abril, N. Cameli, Paolo Iacovelli, Maria Mariano
{"title":"Scabies mimicking relapsing atopic dermatitis","authors":"F. Pigliacelli, E. Abril, N. Cameli, Paolo Iacovelli, Maria Mariano","doi":"10.4081/dr.2024.10070","DOIUrl":"https://doi.org/10.4081/dr.2024.10070","url":null,"abstract":"Atopic dermatitis (AD) is a chronic inflammatory skin disease clinically characterized by eczematous skin manifestations; sometimes it can manifest with non-specific clinical features, in common with other skin conditions, such as infectious and neoplastic diseases. We would like to underline the importance of accurate dermatologic examination and rigorous anamnesis in patient affected by AD, in order to avoid misdiagnosis and delayed treatments.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141922841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blue diode laser as supportive therapy for the management of vulvar lichen sclerosus 蓝色二极管激光作为治疗外阴硬皮病的辅助疗法
IF 2.3
Dermatology Reports Pub Date : 2024-08-09 DOI: 10.4081/dr.2024.10046
Serena Bergamo, M. Gobbo, Silvia Chimenton, Giorgia D'Angelo, Luca Guarda Nardini, Alessandro Gatti
{"title":"Blue diode laser as supportive therapy for the management of vulvar lichen sclerosus","authors":"Serena Bergamo, M. Gobbo, Silvia Chimenton, Giorgia D'Angelo, Luca Guarda Nardini, Alessandro Gatti","doi":"10.4081/dr.2024.10046","DOIUrl":"https://doi.org/10.4081/dr.2024.10046","url":null,"abstract":"Vulvar lichen sclerosus is a chronic inflammatory condition characterized by the thinning and atrophy of the skin and mucosa surrounding the vulva and anus. This study evaluates the efficacy of a treatment protocol utilizing blue-diode laser photobiomodulation in managing vulval lichen sclerosus symptoms in a cohort of 12 female patients. The treatment protocol consisted of laser sessions for 3 times a week for 2 weeks, and follow-up sessions over a 16-week period. Objective and subjective parameters were assessed before treatment, at the end of treatment, and at 4-month follow-up visits. Results demonstrated significant reductions in subjective symptoms such as itching and pain, as well as improvements in objective signs including erythema and fissures. No side effects were observed, indicating the safety and tolerability of laser treatment. These findings suggest that photobiomodulation can be an effective therapeutic option for patients with vulval lichen sclerosus, with future research aimed at refining treatment protocols and evaluating its long-term benefits.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141923606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of tildrakizumab 200 mg for treating difficult-to-treat patient populations with moderate to severe plaque psoriasis 替雷珠单抗 200 毫克治疗中重度斑块状银屑病难治患者的疗效
IF 2.3
Dermatology Reports Pub Date : 2024-08-09 DOI: 10.4081/dr.2024.9999
P. Dapavo, M. Megna, M. Talamonti
{"title":"Efficacy of tildrakizumab 200 mg for treating difficult-to-treat patient populations with moderate to severe plaque psoriasis","authors":"P. Dapavo, M. Megna, M. Talamonti","doi":"10.4081/dr.2024.9999","DOIUrl":"https://doi.org/10.4081/dr.2024.9999","url":null,"abstract":"Psoriasis is an inflammatory chronic disease of the skin typically located on the extensor surfaces of the body, and the trunk. Patients with psoriasis can often present multiple characteristics, such as lesions located in difficult-to-treat (DTT) areas or a high severity of the disease, which can negatively affect their quality of life. There is a lack of consensus in identifying the best therapy for these complex patient populations, especially after the failure of one or multiple lines of therapy. In this regard, we report a case series describing patients with psoriasis located in different DTT areas or presenting a high Psoriasis Area and Severity Index score at baseline and treated ineffectively with prior lines of therapy. Finally, patients achieved complete remission following therapy with tildrakizumab 200 mg (anti-IL-23p19), highlighting its potential efficacy in these patient populations.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141922673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“Mosaic graft” technique and surgical dermal glue in Mohs micrographic surgery and general dermatologic surgery 莫氏显微摄影手术和普通皮肤外科手术中的 "马赛克移植 "技术和外科真皮胶水
IF 2.3
Dermatology Reports Pub Date : 2024-07-15 DOI: 10.4081/dr.2024.9966
G. Vezzoni, Cristina Ricci
{"title":"“Mosaic graft” technique and surgical dermal glue in Mohs micrographic surgery and general dermatologic surgery","authors":"G. Vezzoni, Cristina Ricci","doi":"10.4081/dr.2024.9966","DOIUrl":"https://doi.org/10.4081/dr.2024.9966","url":null,"abstract":"After Mohs Micrographic Surgery dermsurgeons utilise local flaps, full or partial thickness grafts, with good or acceptable cosmetic results. When we are dealing with older and problematic patients, blood thinner users, and non-collaborative people with large facial neoplasms, using flaps may be very difficult and grafts become the best choice. Our aim was to assess a technique to graft very easily, quickly and safely, full thickness skin grafts in facial wounds and have good cosmetic results in those older and problematic people. Ten elderly patients who underwent Mohs Surgery or other surgical procedures have been grafted with this technique that we called “Mosaic graft”, made possible using a dermal glue in a new way. In some cases, for bigger defects, we also assessed the “Stripes” variant of this technique. Graft survival was almost always complete in all cases and after 6 months the cosmetic outcomes were good. This “Mosaic graft” technique and its “Stripes” variant showed good reliability, fast execution, easy harvesting with tissue saving, good cosmetic outcomes, making this technique a very good choice for older and problematic patients.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141645184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erythrasmoid pityriasis versicolor: three case reports and review of the literature 红斑蝶形花：三份病例报告和文献综述
IF 2.3
Dermatology Reports Pub Date : 2024-07-08 DOI: 10.4081/dr.2024.9976
Stefano Veraldi, I. F. Aromolo, Francesca Germiniasi, G. Nazzaro
{"title":"Erythrasmoid pityriasis versicolor: three case reports and review of the literature","authors":"Stefano Veraldi, I. F. Aromolo, Francesca Germiniasi, G. Nazzaro","doi":"10.4081/dr.2024.9976","DOIUrl":"https://doi.org/10.4081/dr.2024.9976","url":null,"abstract":"Pityriasis versicolor is characterized clinically by slightly scaly, hyper- or hypopigmented macules usually located on the chest, shoulders, back and arms. Rare cases of atypical locations of pityriasis versicolor have been described, such as groins, penis and perineum. We present three cases of pityriasis versicolor located exclusively on the submammary folds, pubis and inguinal folds (the latter in an 11-year-old girl), respectively. In consideration of both location and clinical presentation of pityriasis versicolor in these three patients, we think that the diagnosis of “erythrasmoid” pityriasis versicolor is acceptable. Differential diagnosis with erythrasma must be taken into consideration. Mycological and bacteriological examinations are therefore necessary in order to make a correct diagnosis and specific therapy.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141667572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutaneous larva migrans: is dermoscopy useful for the treatment? 皮肤蚴移行症：皮肤镜对治疗有用吗？
IF 2.3
Dermatology Reports Pub Date : 2024-07-08 DOI: 10.4081/dr.2024.10049
Giulia Bazzacco, Carlotta Nardello, R. D. Caposiena Caro, N. di Meo, I. Zalaudek, Marina Agozzino
{"title":"Cutaneous larva migrans: is dermoscopy useful for the treatment?","authors":"Giulia Bazzacco, Carlotta Nardello, R. D. Caposiena Caro, N. di Meo, I. Zalaudek, Marina Agozzino","doi":"10.4081/dr.2024.10049","DOIUrl":"https://doi.org/10.4081/dr.2024.10049","url":null,"abstract":"Cutaneous larva migrans (CLM) is a zoonotic disease endemic in tropical regions. CLM diagnosis mainly relies on the morphology of the skin lesions, however dermoscopy can improve diagnostic accuracy. In this paper, we report two cases of CLM to highlight the importance of dermoscopic follow-up in early identification of treatment failure, as well as the effectiveness of topical ivermectin as a combined medication.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141666925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dermoscopy of Riehl’s melanosis: a case report and a short review of the literature 皮肤镜下的里氏黑变病：病例报告和文献简评
IF 2.3
Dermatology Reports Pub Date : 2024-07-04 DOI: 10.4081/dr.2024.9983
Benedetta Sonego, Giulia Bazzacco, E. Zelin, C. Conforti, I. Zalaudek, N. di Meo
{"title":"Dermoscopy of Riehl’s melanosis: a case report and a short review of the literature","authors":"Benedetta Sonego, Giulia Bazzacco, E. Zelin, C. Conforti, I. Zalaudek, N. di Meo","doi":"10.4081/dr.2024.9983","DOIUrl":"https://doi.org/10.4081/dr.2024.9983","url":null,"abstract":"Riehl’s melanosis (RM) is a pigmentary disorder, more common in individuals with dark skin phototypes, considered a form of pigmented contact dermatitis. In this paper we present a case of RM due to the rubber component of a work facial mask in which dermoscopy and patch test were the most important tools to help physicians in diagnosis. In addition, we reviewed the main dermoscopic clues that may be useful in differential diagnosis with others facial pigmentary disorders.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141678868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Repair of a medial canthal defect 修复内侧眼眶缺损
IF 2.3
Dermatology Reports Pub Date : 2024-07-03 DOI: 10.4081/dr.2024.10001
Alberto Murtas, Virginia Maffei, Fabrizio Fantini
{"title":"Repair of a medial canthal defect","authors":"Alberto Murtas, Virginia Maffei, Fabrizio Fantini","doi":"10.4081/dr.2024.10001","DOIUrl":"https://doi.org/10.4081/dr.2024.10001","url":null,"abstract":"An 87-year-old man presented for treatment of a histology-proven basal cell carcinoma involving the left medial canthus. The lesion was successfully resected with adequate margins under local anaesthesia and resulted in a defect measuring 2 x 1.5 cm. How would you repair this defect?","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141683759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vitiligo in the 19th-century dermatological works of Vincenzo Chiarugi, Robert Willan, Jean-Louis Alibert, and Ferdinand von Hebra Vincenzo Chiarugi、Robert Willan、Jean-Louis Alibert 和 Ferdinand von Hebra 的 19 世纪皮肤科著作中的白癜风
IF 2.3
Dermatology Reports Pub Date : 2024-07-03 DOI: 10.4081/dr.2024.10042
Flavio Stocco, Mauro Picardo, Viviana Lora
{"title":"Vitiligo in the 19th-century dermatological works of Vincenzo Chiarugi, Robert Willan, Jean-Louis Alibert, and Ferdinand von Hebra","authors":"Flavio Stocco, Mauro Picardo, Viviana Lora","doi":"10.4081/dr.2024.10042","DOIUrl":"https://doi.org/10.4081/dr.2024.10042","url":null,"abstract":"Vitiligo is an iconic dermatological pathology as its clinical manifestations indelibly mark the patient through the appearance of white spots all over the body. The oldest written testimonies referring to vitiligo are: the first texts of Ayurveda, the Ebers Papyrus and the Leviticus of the Old Testament. During the Roman Empire, the doctors Aulus Cornelius Celsus and Galen, respectively in the I and II centuries AD, were the first to describe this skin disease and their statements were used by all subsequent authors. Hieronymus Mercurialis in the XVI century, Joseph Jakob Ritter Plenck in the XVIII century and Vincenzo Chiarugi again in the XIX century based their writings on the references of the two Roman doctors. After centuries of scientific inaction in the XIX century, there was an exponential increase in dermatological studies and the medical-scientific works produced in this period laid the foundations of modern dermatology. The nineteenth-century texts of Robert Willan and Thomas Bateman, Jean-Louis Alibert, Ferdinand von Hebra, and Moriz Kaposi proved fundamental for the study of skin pathologies, including vitiligo. The nineteenth-century medical-scientific vision and approach to vitiligo is shown in this work through the presentation of direct quotes extrapolated from the most important works of the authors mentioned above, this served to historically contextualize the gradual progress of medical study regarding this skin pathology.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survey of the impact of BOLT-trial data on oncologists’ and dermatologists’ decision-making in treating patients with locally advanced basal cell carcinoma 调查 BOLT 试验数据对肿瘤学家和皮肤科医生治疗局部晚期基底细胞癌患者决策的影响
IF 2.3
Dermatology Reports Pub Date : 2024-07-03 DOI: 10.4081/dr.2024.9882
L. Scarpato, M. Palla, S. Strippoli, L. Tagliaferri, Luca Fania, M. Saponara, A. Carbone, F. Spagnolo, Flavia Silvestri, P. Ascierto
{"title":"Survey of the impact of BOLT-trial data on oncologists’ and dermatologists’ decision-making in treating patients with locally advanced basal cell carcinoma","authors":"L. Scarpato, M. Palla, S. Strippoli, L. Tagliaferri, Luca Fania, M. Saponara, A. Carbone, F. Spagnolo, Flavia Silvestri, P. Ascierto","doi":"10.4081/dr.2024.9882","DOIUrl":"https://doi.org/10.4081/dr.2024.9882","url":null,"abstract":"Basal cell carcinoma (BCC) is the most common malignant tumour in white populations. Multiple studies demonstrated that the aberrant activation of Hedgehog signaling is a driver of BCC development, and its blockade represents a potential therapeutic target. In Italy, clinicians can prescribe Hedgehog inhibitors (HhIs) Vismodegib and Sonidegib. To highlight the treatment choice of clinicians, we conducted an online survey between November 1 and November 18, 2020 with 33 Italian clinicians from 27 reference hospitals, in which each participant received an anonymous survey consisting of two multiple-choice questions on clinical efficacy and safety profile of Sonidegib and Vismodegib. Respondents reported their opinions on which efficacy and tolerability data of the pivotal phase-II BOLT trial were more relevant in the treatment choice of patients with locally advanced BCC (laBCC). This survey shows that overall response rate (ORR) and the duration of response (DoR) are the most expected across dermatologists and oncologists. The different pharmacokinetic profile of the two HhIs are behind their diverse toxicity spectrum, dose and schedule modification seem to address the choice between vismodegib and sonidegib among dermato-oncology prescribers.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141681961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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