{"title":"The landscape of dermatology: the critical role of diversity, equity, and inclusion.","authors":"Emilie A Foltz, Harkirat K Minhas, Joel Bervell","doi":"10.4081/dr.2025.10389","DOIUrl":"https://doi.org/10.4081/dr.2025.10389","url":null,"abstract":"<p><p>The landscape of dermatology is undergoing a significant transformation as the field grapples with the implications of diversity, equity, and inclusion (DEI) initiatives. These efforts are pivotal in addressing and reducing disparities in patient outcomes, particularly for people of color (POC). This summary examines the disparities in dermatology, the importance of DEI initiatives, the impact of a recent Supreme Court decision, and the ongoing debates within the American Academy of Dermatology (AAD) regarding DEI policies. [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Flavio Stocco, Carlo Cota, Maria Concetta Fargnoli, Viviana Lora
{"title":"Psoriasis treatments in Europe during the 19<sup>th</sup> century.","authors":"Flavio Stocco, Carlo Cota, Maria Concetta Fargnoli, Viviana Lora","doi":"10.4081/dr.2025.1028","DOIUrl":"https://doi.org/10.4081/dr.2025.1028","url":null,"abstract":"<p><p>Psoriasis is a dermatological disorder whose clinical manifestations have attracted the interest of physicians since ancient times. Hippocrates of Cos in the 5th century B.C. and later Galen in the 1st century A.D. were the first to refer to skin lesions characterized by scales and itching. In the 19th century, dermatology progressed, gaining scientific autonomy and leading to improvements both in the clinical study of psoriasis and in the search for new treatment methodologies. The dermatological schools established in this century, located in London, Paris, and Vienna, dedicated themselves to studying skin diseases, adopting unique methodological approaches and creating dermatological nomenclature. The English school focused on the objective description of lesions, while the French school was the first to approach the study of evolutionary processes, formulating theories not always based on experimental methods. Finally, the Austrian school based its research entirely on the study of diseases through the use of instruments and laboratory tests. Representatives of all three schools played a crucial role in the scientific progress of dermatology, leading to the subsequent evolution and improvement of therapies, which gradually replaced the use of ancient remedies and archaic administration methods. The treatments promoted by the different 19th-century European dermatologists reflected both their scientific thinking and the medical beliefs of the time. For this reason, the following historical-medical reconstruction of the evolution of psoriasis therapies in the 19th century can contribute to enriching the studies of dermatology.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Carugno, Emanuela Passoni, Giovanna Pogliaghi, Francesca Morgese, Elena Maccaroni, Paola Ghiorzo, Lorenza Pastorino, Bruna Dalmasso, William Bruno, Monica Barile
{"title":"Italian Melanoma Intergroup tele-genetic counseling project for melanoma predisposition syndromes: five-year evaluation of effectiveness and outcomes.","authors":"Andrea Carugno, Emanuela Passoni, Giovanna Pogliaghi, Francesca Morgese, Elena Maccaroni, Paola Ghiorzo, Lorenza Pastorino, Bruna Dalmasso, William Bruno, Monica Barile","doi":"10.4081/dr.2025.10510","DOIUrl":"https://doi.org/10.4081/dr.2025.10510","url":null,"abstract":"<p><p>This study assessed the implementation of a tele-genetic counseling (TGC) pathway for hereditary melanoma risk using the culturally adapted Italian Melanoma Intergroup Tele-Genomics Outcome Scale (IMI-TGOS) questionnaire. Among 278 eligible patients, 177 (64%) completed the survey across three Italian centers. Responses showed high comprehension and perceived utility: 88% of participants reported understanding the information received, 96% recognized familial implications, and over 85% felt confident in managing risk and making decisions. While emotional responses were more varied, most respondents expressed confidence in future planning. These findings confirm the feasibility, acceptability, and informativeness of the IMI-TGOS in a remote counseling setting. The study supports the comparability of tele-genetic and in-person counseling in terms of understanding, retention, and decision-making. Moreover, the IMI-TGOS emerged as a promising tool for evaluating real-world genetic services. Broader adoption may help monitor outcomes and improve quality and equity in the expanding landscape of digital genetic care.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical features, safety, and efficacy of combining Q-switched Nd:YAG laser and FOB<sup>®</sup> Tri-White Serum in melasma treatment.","authors":"Thi Xuan Tam Huynh, Bay Quach Thi","doi":"10.4081/dr.2025.10270","DOIUrl":"https://doi.org/10.4081/dr.2025.10270","url":null,"abstract":"<p><p>Melasma is a benign skin condition characterized by hyperpigmented patches, primarily affecting the face, and significantly reducing patients' quality of life. Treatment is challenging due to its recurrent nature, with no single modality proving universally effective. The combination of Q-switched Nd:YAG laser treatment and FOB® Tri-White Serum (Hong Nhung Cosmetics Co., Ltd., Can Tho, Vietnam) may represent a promising new therapeutic approach. This cross-sectional descriptive study involved 85 female patients with melasma treated at two dermatological centers between July 2023 and June 2024. Patients underwent four Q-switched Nd:YAG laser sessions (1064 nm, 1.5-1.7 J/cm2) at three-week intervals and applied FOB® Tri-White Serum twice or three times daily. Treatment effectiveness was assessed using the Melasma Area Severity Index (MASI) score and the Felix Von Luschan skin color chart. Data were analyzed using Stata 17.0 MP, with p<0.05 considered statistically significant. The mean MASI score improved significantly from 7.5±4.7 to 4.9±3.5 (p<0.05), with a 69.4% response rate. Younger patients (<45 years), individuals with a shorter disease duration (≤36 months), and cases of mild to moderate melasma exhibited more favorable outcomes. Adverse effects from both the laser and serum were mild and transient. The combination of Q-switched Nd:YAG laser and FOB® Tri-White Serum is a safe and effective treatment for melasma, demonstrating significant improvement in pigmentation with minimal side effects. Further research is needed to validate these findings with larger sample sizes and control groups.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144946155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Red tattoo allergies after REACH regulation: a continuing problem.","authors":"Sebastiaan Van der Bent","doi":"10.4081/dr.2025.10462","DOIUrl":"https://doi.org/10.4081/dr.2025.10462","url":null,"abstract":"<p><p>Despite new EU regulations, allergies to red ink tattoos remain an urgent public health problem. Red tattoo pigments continue to occur at a clinically relevant rate. This observation raises critical questions about the effectiveness, scope, and enforcement of the Registration, Evaluation, Authorisation, and Restriction of Chemicals (REACH) regulation. We argue that current tattoo ink restrictions fail to sufficiently protect European consumers from known allergens and that regulatory revisions are urgently needed.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144946101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hamad J Aldhafiri, Hind Alshalhoob, Salma Mohammed Alshreef, Farah Abdullah Alassaf, Albatool Aljofan, Halah Omar Alamawi, Sara AlNowaiser, Hind M Almohanna
{"title":"Hair greying associated with rosemary use: a cross-sectional study in Saudi Arabia.","authors":"Hamad J Aldhafiri, Hind Alshalhoob, Salma Mohammed Alshreef, Farah Abdullah Alassaf, Albatool Aljofan, Halah Omar Alamawi, Sara AlNowaiser, Hind M Almohanna","doi":"10.4081/dr.2025.10126","DOIUrl":"https://doi.org/10.4081/dr.2025.10126","url":null,"abstract":"<p><p>The sociological and psychological consequences of premature hair greying (PHG) are significant. PHG has been linked to various intrinsic and extrinsic factors, including genetic predispositions and environmental influences. The widespread use of hair growth-stimulating products may impact the hair greying process. This cross-sectional study aimed to determine the prevalence of hair greying among rosemary users in the Saudi Arabian population. A self-administered questionnaire was distributed among the sample population in the form of an online survey. This questionnaire included sociodemographic data (e.g., age, gender, and education), the use of several types of rosemary, and the outcomes. A total of 994 participants completed the survey, the majority of whom were female (94.4%). Participants aged between 18 and 24 years represented 64% of the sample. Hair loss was reported by 75.4% of respondents. More than half (58.7%) reported using rosemary, particularly rosemary oil, as a treatment. Among those who used rosemary, 22.8% reported experiencing hair greying. Increasing age emerged as an independent risk factor for PHG. However, multivariate regression analysis showed that the use of rosemary oil was associated with a reduced likelihood of hair greying. Approximately 25% of rosemary users developed PHG, and Individuals in the early to middle-age range with a bachelor's degree or higher had a 1.5 to 3.5 times greater risk of hair greying. Nevertheless, the use of rosemary oil appeared to mitigate this risk. Additional observational studies are needed to validate the high regional prevalence of hair greying, potentially associated with rosemary use.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144946107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Virone, Elena Zappia, Alberto Di Caro, Davide Carlesimo, Nicoletta Bernardini, Giovanni Pellacani, Antonio Giovanni Richetta, Steven Paul Nisticò, Annunziata Dattola
{"title":"Hidradenitis suppurativa: state-of-the-art review and update.","authors":"Marco Virone, Elena Zappia, Alberto Di Caro, Davide Carlesimo, Nicoletta Bernardini, Giovanni Pellacani, Antonio Giovanni Richetta, Steven Paul Nisticò, Annunziata Dattola","doi":"10.4081/dr.2025.10328","DOIUrl":"https://doi.org/10.4081/dr.2025.10328","url":null,"abstract":"<p><p>Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by painful nodules, abscesses, and draining tunnels in areas such as the axillae, groin, and inframammary regions. It typically emerges in early adulthood, with a global prevalence of approximately 1%, though regional variations exist. HS significantly affects patients' quality of life and imposes considerable socioeconomic burdens. It is frequently associated with metabolic syndrome, inflammatory arthritis, and inflammatory bowel disease, reflecting its underlying systemic inflammatory nature. The pathogenesis of HS involves innate immune mechanisms, including macrophages, neutrophils, interleukin (IL)-1β, tumor necrosis factor-alpha (TNF-α), and granulocyte colony-stimulating factor, alongside adaptive immune responses mediated by T cells (IL-17, interferon-gamma [IFN-γ]) and B cells, which contribute to autoantibody formation and tertiary lymphoid structures. Chronic inflammation results in irreversible tissue damage, tunnel formation, and severe scarring. Treatment strategies vary based on disease severity. Early inflammatory stages benefit from pharmacological therapies, while later stages require a combination of medical and surgical interventions, with surgery often necessary for advanced cases. The introduction of targeted biologic therapies, including TNF-α (adalimumab) and IL-17 inhibitors (secukinumab, bimekizumab), has expanded treatment options beyond traditional antibiotic regimens. Effective management focuses on early intervention to prevent irreversible damage, control symptoms such as pain, and address systemic comorbidities. A timely diagnosis, along with a multidisciplinary and personalized approach, is essential for improving patient outcomes and quality of life.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144946135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dermatology ReportsPub Date : 2025-08-22Epub Date: 2025-02-20DOI: 10.4081/dr.2025.10276
Lulwa Alogayell, Sarah Alrashid, Sahar Alruhaimi, Raneem Najjar
{"title":"Nevus of Ota with excellent response to Q-switched Nd:YAG pigmented laser: a case report.","authors":"Lulwa Alogayell, Sarah Alrashid, Sahar Alruhaimi, Raneem Najjar","doi":"10.4081/dr.2025.10276","DOIUrl":"10.4081/dr.2025.10276","url":null,"abstract":"<p><p>Nevus of Ota is a benign pigmentation disorder that commonly affects areas of the skin and eyes innervated by the ophthalmic and maxillary branches of the trigeminal nerve. It typically presents as blue-black or gray macules, mainly in individuals with darker skin tones, and can cause significant cosmetic concerns. Treatment options include cryotherapy, dermabrasion, and laser therapy, with the Q-switched (QS) Nd:YAG (1064 nm) laser emerging as a promising option. This report describes the case of a 25-year-old woman diagnosed with unilateral nevus of Ota. After clinical examination, the patient was treated with the QS Nd:YAG laser, undergoing 12 treatment sessions over three years. A significant reduction in pigmentation was observed with no adverse effects. This case demonstrates the effectiveness of the QS Nd:YAG laser in managing nevus of Ota and highlights the importance of appropriate laser settings, patient selection, and post-treatment care. Laser therapy, particularly with the QS Nd:YAG laser, may offer a reliable and durable solution for reducing pigmentation and improving the cosmetic appearance of patients with this condition.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145032832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dermatology ReportsPub Date : 2025-08-22Epub Date: 2025-01-14DOI: 10.4081/dr.2025.10039
Szymon Mućka, Martyna Miodońska, Magdalena Mróz-Dybowska, Anna Źlik, Alicja Grzanka, Robert Pawłowicz, Andrzej Bożek
{"title":"Multimorbidity in adult patients diagnosed with atopic dermatitis.","authors":"Szymon Mućka, Martyna Miodońska, Magdalena Mróz-Dybowska, Anna Źlik, Alicja Grzanka, Robert Pawłowicz, Andrzej Bożek","doi":"10.4081/dr.2025.10039","DOIUrl":"10.4081/dr.2025.10039","url":null,"abstract":"<p><p>Atopic dermatitis (AD) may be associated with other diseases that could impact the patient's overall health. The aim of this study was to assess the comorbidities observed in patients diagnosed with AD and psoriasis compared to healthy patients. Patients aged 18 and older were recruited using the medical databases of dermatology clinics. Initially, 378 patients were selected via an analysis of the International Classification of Diseases - tenth revision (ICD-10) codes. Ultimately, 231 patients with atopic dermatitis were included in the study group based on their fulfillment of the Hanifin and Rajka criteria. The sample comprised 104 women and 127 men with an age range of 18-62. In patients with AD, selected lifestyle diseases such as obesity and atherosclerosis occurred significantly less frequently than in patients without AD, including those with other dermatoses. In addition, allergic asthma and type 2 diabetes occurred significantly more often in AD patients than in those without AD (p<0.05).</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144946112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lucio phenomenon: a case report on an overlooked reaction in lepromatous leprosy.","authors":"Natsuda Sajjachareonpong, Poonnawis Sudtikoonaseth, Kowit Kampirapap, Monton Tanabodee, Sutsarun Prunglumpoo, Chanisa Kiatsurayanon","doi":"10.4081/dr.2025.10173","DOIUrl":"10.4081/dr.2025.10173","url":null,"abstract":"<p><p>Our patient presented with a 5-year history of chronic, asymptomatic papulonodular lesions on the extremities. Over the past 8 months, the lesions have spread to the face and earlobes, and new ulcerative lesions have appeared on both legs. Skin biopsy was compatible with lepromatous leprosy with Lucio phenomenon. Lucio phenomenon is a rare type of leprosy reaction found mostly in neglected lepromatous leprosy cases. Unfortunately, the patient developed pulmonary embolism and passed away. This case report focuses on the clinicopathological characteristics and management of Lucio phenomenon, which is an unusual form of leprosy reaction that often carries a poorer prognosis. Importantly, physicians should be able to differentiate the Lucio phenomenon from other types of leprosy reactions for prompt management.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}