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Epidemiological and clinical profiles of cutaneous leishmaniasis cases in Amhara National Regional State, Northwest Ethiopia: a multicenter retrospective study.
IF 2.3
Dermatology Reports Pub Date : 2025-02-06 Epub Date: 2024-11-04 DOI: 10.4081/dr.2024.10089
Bizuayehu Gashaw, Endalew Yizengaw, Endalkachew Nibret, Addisu Workineh, Adisu Abebe
{"title":"Epidemiological and clinical profiles of cutaneous leishmaniasis cases in Amhara National Regional State, Northwest Ethiopia: a multicenter retrospective study.","authors":"Bizuayehu Gashaw, Endalew Yizengaw, Endalkachew Nibret, Addisu Workineh, Adisu Abebe","doi":"10.4081/dr.2024.10089","DOIUrl":"10.4081/dr.2024.10089","url":null,"abstract":"<p><p>Cutaneous leishmaniasis (CL) is caused by Leishmania parasites. Ethiopia is one of the top ten countries with a high CL load, and Amhara National Regional State (ANRS) is one of the CL hotspot areas in the country. This study examined cutaneous leishmaniasis's epidemiology and clinical profiles in the ANRS region. It was conducted from April to October 2023 across eight Leishmaniasis Treatment Centres (LTCs). A data review was done from patients presenting to these centers between June 2018 and July 2023. Chi-square test and logistic regression were performed using SPSS-23. A total of 1729 patients with CL were recorded, resulting in an overall burden of 8.6 cases per 10,000 outpatients. Patients were from 112 districts, and most of them (71.1%) presented with localized cutaneous leishmaniasis (LCL). Approximately 12% of patients lived with the disease for over a year without treatment, while 13.2% of patients were multiple-time comers. Cutaneous leishmaniasis continues to be a significant public health issue in the ANRS region. Approximately onethird of CL patients exhibit the mucocutaneous leishmaniasis (MCL) clinical form. There has been a notable delay among CL patients in seeking diagnosis and treatment. It is essential to conduct large-scale community-based studies and studies focused on both traditional and modern treatment centers to accurately estimate the prevalence of CL in the region. Follow-up and molecular studies are crucial for enhancing our understanding of the clinical features of the disease. Furthermore, raising community awareness about CL prevention and control can help patients obtain early diagnosis and treatment.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lichen planus pigmentosus inversus: case report and systematic review.
IF 2.3
Dermatology Reports Pub Date : 2025-02-06 Epub Date: 2024-10-11 DOI: 10.4081/dr.2024.10000
Fabio Massimo Gavazzoni, Federico Patta, Carla Nobile, Ilaria Girolami
{"title":"Lichen planus pigmentosus inversus: case report and systematic review.","authors":"Fabio Massimo Gavazzoni, Federico Patta, Carla Nobile, Ilaria Girolami","doi":"10.4081/dr.2024.10000","DOIUrl":"10.4081/dr.2024.10000","url":null,"abstract":"<p><p>Lichen planus pigmentosus inversus (LPPI) is a rare variant of lichen planus characterized by well-demarcated, often slight pruritic, dark-gray plaques in intertriginous zones, hence the attribute of \"inversus\". It was originally described by Pock et al. in 2001, and less than 100 cases have been reported to date. Here, we present a case of a 52-year-old male with a two-month duration of gray-brownish plaques in bilateral axillary, submammary, antecubital, and inguinal folds. No triggering agent was present, and the biopsy showed an interface/lichenoid dermatitis with plenty of pigment incontinence. Topical tacrolimus 0.1% ointment was administered with moderate improvement at five weeks. A review of the literature showed no significant differences in involved sites and age distribution among genders, with a slightly longer duration of manifestations in females. The most administered therapeutic agents were topical corticosteroids, alone or in combination with other agents, and tacrolimus.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of keloids with pulsed dye laser in a pediatric population.
IF 2.3
Dermatology Reports Pub Date : 2025-02-06 Epub Date: 2024-10-15 DOI: 10.4081/dr.2024.10067
Riccardo Cavalli, Nicola Adriano Monzani, Italo Francesco Aromolo
{"title":"Treatment of keloids with pulsed dye laser in a pediatric population.","authors":"Riccardo Cavalli, Nicola Adriano Monzani, Italo Francesco Aromolo","doi":"10.4081/dr.2024.10067","DOIUrl":"https://doi.org/10.4081/dr.2024.10067","url":null,"abstract":"<p><p>Several studies confirmed the role of pulsed dye laser (PDL) in successfully treating keloids. To our knowledge, this is the first study conducted entirely in children (<14 years old). Case notes and photographic records of 16 pediatric patients with keloids treated with PDL at our center between 2012 and 2019 were reviewed. The red tone of the lesion before the first treatment, number of sessions, clinical improvement, and the evaluation of the satisfaction of patients have been reported. An excellent clearance has been achieved in 7 out of 16 (43.8%) cases, a good-moderate clearance in 7 patients (43.8%), and a slight clearance in 2 patients (12.4%). No patients detected absent or low results. A total of 13 out of 16 patients (81.2%) were satisfied. Lesions with higher red-tone grades could benefit from multiple treatment sessions. PDL is an effective treatment of keloids in the pediatric population, characterized by a good safety profile and high satisfaction. We observed good results treating the active remodeling lesions with a higher red tone. These data need to be confirmed with further studies in a larger set of pediatric patients.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Facial wrinkle categorization using convolutional neural network.
IF 2.3
Dermatology Reports Pub Date : 2025-02-06 Epub Date: 2024-09-12 DOI: 10.4081/dr.2024.10034
Čedomir Vasić
{"title":"Facial wrinkle categorization using convolutional neural network.","authors":"Čedomir Vasić","doi":"10.4081/dr.2024.10034","DOIUrl":"10.4081/dr.2024.10034","url":null,"abstract":"<p><p>A tool for detecting and classifying wrinkles on the facial skin is always welcomed in the pursuit of tight and beautiful skin. If this tool involves using a state-of-the-art neural network and high-quality images, it is highly likely to be practical. Five thousand and ninety-eight images were categorized into four classes by a trained expert and prepared for neural network training. The task was to determine whether such prepared data could serve as good material for learning and whether they could provide sufficiently high accuracy in prediction. It was found that the answer to this question is positive.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11904767/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Calcipotriol as a daylight photodynamic therapy enhancer: a case-control study.
IF 2.3
Dermatology Reports Pub Date : 2025-02-06 Epub Date: 2024-10-01 DOI: 10.4081/dr.2024.10077
Benedetta Sonego, Enrico Zelin, Serena Bonin, Tommaso Pozzebon, Giulia Bazzacco, Andrea Corio, Marina Agozzino, Dante Raffaele Caro Caposiena, Iris Zalaudek, Nicola Di Meo
{"title":"Calcipotriol as a daylight photodynamic therapy enhancer: a case-control study.","authors":"Benedetta Sonego, Enrico Zelin, Serena Bonin, Tommaso Pozzebon, Giulia Bazzacco, Andrea Corio, Marina Agozzino, Dante Raffaele Caro Caposiena, Iris Zalaudek, Nicola Di Meo","doi":"10.4081/dr.2024.10077","DOIUrl":"10.4081/dr.2024.10077","url":null,"abstract":"<p><p>Actinic keratoses (AKs) are common skin lesions found on sun-exposed areas and are considered potential precursors to squamous cell carcinomas (SCCs). This observational case-control study evaluates the efficacy of combining traditional daylight photodynamic therapy (DL-PDT) with pre-treatment using 0.005% calcipotriol (CAL) ointment. Twenty immunocompetent male patients with grade I-II AKs on the scalp and/or face were randomized into two groups: the case group received a 14-day pre-treatment with CAL ointment before DL-PDT, while the control group used a moisturizing cream. Both groups underwent a series of three DL-PDT sessions. The study utilized the Actinic Keratosis Area Severity Index (AKASI) scoring system to measure the actinic damage at baseline, 3 months, and 6 months post-treatment. Results showed a significant reduction in AKASI scores in the CAL group compared to controls, indicating that CAL pretreatment enhances the efficacy of DL-PDT. This combination treatment was well tolerated, with minimal discomfort reported. The findings suggest that incorporating CAL into the treatment regimen can improve the clearance of AKs and potentially prevent their progression to SCCs.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trichoscopy and LC-OCT findings in sonidegib-induced alopecia in patients with advanced basal cell carcinoma.
IF 2.3
Dermatology Reports Pub Date : 2025-02-06 Epub Date: 2024-09-27 DOI: 10.4081/dr.2024.10113
Irina Ciobotariu, Gerardo Palmisano, Giacomo Caldarola, Alfredo Piccerillo, Francesco Tassone, Simone Cappilli, Alessandro Di Stefani, Ketty Peris
{"title":"Trichoscopy and LC-OCT findings in sonidegib-induced alopecia in patients with advanced basal cell carcinoma.","authors":"Irina Ciobotariu, Gerardo Palmisano, Giacomo Caldarola, Alfredo Piccerillo, Francesco Tassone, Simone Cappilli, Alessandro Di Stefani, Ketty Peris","doi":"10.4081/dr.2024.10113","DOIUrl":"10.4081/dr.2024.10113","url":null,"abstract":"<p><p>Sonidegib is a Hedgehog pathway inhibitor (HHI) used as a first-line systemic treatment for patients with advanced basal cell carcinoma (aBCC). Alopecia is reported as a frequent adverse event (AE), occurring in 49% of patients. Forty-five patients with aBCC were treated with sonidegib between December 2022 and December 2023; among them, 11/45 patients developed alopecia. Trichoscopic features included yellow dots, black dots, exclamation mark hairs, and broken hairs. Upon LC-OCT examination, yellow dots were seen as dilated follicular dark spaces containing malted, nonhomogeneous material and outlined by bright collarets. Black dots corresponded to normal-sized follicular ostia filled with bright, homogeneous material and cadaverized hair. Exclamation mark hairs were short, dark dysmorphic hairs with different sizes of proximal and distal ends, and broken hairs were short dysmorphic hairs. LC-OCT may provide additional insights into early signs and clinical evolution of sonidegib-induced alopecia in patients with aBCC.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Teledermatology: Canadian dermatologists' practice patterns, perceived challenges and future recommendations.
IF 2.3
Dermatology Reports Pub Date : 2025-02-06 DOI: 10.4081/dr.2025.10197
Sidra Sarfaraz, Tarek Turk, Samuel A J Lowe, Luvneet Verma, Marlene Dytoc
{"title":"Teledermatology: Canadian dermatologists' practice patterns, perceived challenges and future recommendations.","authors":"Sidra Sarfaraz, Tarek Turk, Samuel A J Lowe, Luvneet Verma, Marlene Dytoc","doi":"10.4081/dr.2025.10197","DOIUrl":"https://doi.org/10.4081/dr.2025.10197","url":null,"abstract":"<p><p>The use of teledermatology has increased significantly in recent years. The objective of this study was to determine Canadian dermatologists' and dermatology residents' perspectives on teledermatology. An online survey was created to determine participants' teledermatology practice patterns and their perception of the challenges, education, training, and research in teledermatology. The survey was distributed through the Canadian Dermatology Association and by administrative staff at Canadian Dermatology departments. There were 33 respondents: 66.7% of respondents started using teledermatology during the COVID-19 pandemic, and 93.8% reported that teledermatology accounted for 0-25% of their practice. Convenience, access, and safety were identified as the primary advantages of teledermatology. Teledermatology was mainly utilized for medication monitoring or refills and to assess, manage, or follow up on dermatitis, other chronic inflammatory conditions, and pre-diagnosed dermatologic conditions. Poor photo quality (32.3%) and the inability to conduct physical examinations or accurately diagnose conditions (74.2%) were reported as significant challenges. Respondents recommended education on the medicolegal considerations of teledermatology and research on how teledermatology compares to in-person consultations. Overall, teledermatology offers convenience, access, and improved safety for patients and healthcare professionals. However, addressing challenges related to physical examinations, accurate diagnoses, and photo quality is essential for optimal care delivery.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New and emerging therapies in cutaneous T-cell lymphoma.
IF 2.3
Dermatology Reports Pub Date : 2025-02-06 Epub Date: 2024-10-02 DOI: 10.4081/dr.2024.10002
Gabriele Roccuzzo, Nicole Macagno, Silvia Giordano, Paolo Fava, Pietro Quaglino
{"title":"New and emerging therapies in cutaneous T-cell lymphoma.","authors":"Gabriele Roccuzzo, Nicole Macagno, Silvia Giordano, Paolo Fava, Pietro Quaglino","doi":"10.4081/dr.2024.10002","DOIUrl":"https://doi.org/10.4081/dr.2024.10002","url":null,"abstract":"<p><p>Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma (CTCL) that typically presents in the early phase as inflammatory erythematous patches or plaques, with epidermotropism as the histopathological hallmark of the disease. Traditionally, in the early stages, non-aggressive options represent the first-line strategy: topical corticosteroids, phototherapy, radiotherapy, and occasionally adopting a \"wait-and-see\" approach for minimally symptomatic patients. In patients with advanced or recurrent disease, good results can be achieved with immune modifiers, chemotherapeutic agents, total skin irradiation, or extracorporeal photochemotherapy, and maintenance therapy is often required. The past decade has seen an expansion of therapies that can be used in this setting by increasing new therapeutic strategies. The key advancements coming from recently published trials are resumed in this article.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Face scabies in the elderly: when dermoscopy can be a game changer.
IF 2.3
Dermatology Reports Pub Date : 2025-02-06 Epub Date: 2024-10-03 DOI: 10.4081/dr.2024.10115
Andrea Corio, Enrico Zelin, Vanessa Mazzoletti, Benedetta Sonego, Camilla Brunello, Nicola Di Meo, Iris Zalaudek
{"title":"Face scabies in the elderly: when dermoscopy can be a game changer.","authors":"Andrea Corio, Enrico Zelin, Vanessa Mazzoletti, Benedetta Sonego, Camilla Brunello, Nicola Di Meo, Iris Zalaudek","doi":"10.4081/dr.2024.10115","DOIUrl":"10.4081/dr.2024.10115","url":null,"abstract":"<p><p>Dear Editor, Scabies is a common pruritic ectoparasitic infestation of the skin caused by the mite Sarcoptes scabiei. It classically presents as an intensely pruritic eruption that usually involves hands and interdigital folds, wrists, axillae, areolae, abdomen, and genitalia. In immunocompetent adults, mite infestation affecting the face is considered exceptional; accordingly, if topical treatment is chosen, clinicians typically instruct patients to apply the product to the body, excluding the head area. [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erythema multiforme following Orf viral infection: a comprehensive review of the literature with a case report highlight.
IF 2.3
Dermatology Reports Pub Date : 2025-02-06 Epub Date: 2024-09-13 DOI: 10.4081/dr.2024.10032
Mona Alkallabi, Khalid Nabil Nagshabandi, Shaden Alobaid, Reem Bin Idris, Amany Fathaddin
{"title":"Erythema multiforme following Orf viral infection: a comprehensive review of the literature with a case report highlight.","authors":"Mona Alkallabi, Khalid Nabil Nagshabandi, Shaden Alobaid, Reem Bin Idris, Amany Fathaddin","doi":"10.4081/dr.2024.10032","DOIUrl":"https://doi.org/10.4081/dr.2024.10032","url":null,"abstract":"<p><p>Orf, also known as ecthyma contagiosum, is a highly contagious zoonotic infection linked to direct contact with infected sheep, goats, or reindeer, posing a significant risk to farmers, veterinarians, shepherds, and butchers. This study presents a case of a 41-year-old female who developed Orf, complicated by the rare occurrence of erythema multiforme (EM), after handling sheep meat. The patient initially presented with a progressive, painful skin eruption on the left dorsum of the little finger, which subsequently worsened and led to the development of generalized painful and itchy skin lesions, including target lesions typical of EM, on the palms, soles, and extremities. The diagnosis was confirmed through clinical examination and skin biopsy. The patient was treated with antihistamines and topical corticosteroids, resulting in a complete resolution of symptoms within three weeks. We underscore the importance of recognizing EM as a potential complication of Orf infection, particularly in individuals with occupational animal exposure.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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