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Complications in nail surgery and prevention strategies: a comprehensive review. 甲外科并发症及预防策略综述。
IF 1.3
Dermatology Reports Pub Date : 2025-08-22 Epub Date: 2025-02-04 DOI: 10.4081/dr.2025.10216
Anna Bolzon, Bertrand Richert, Giuseppe Emilio Cannata, Andrea Sechi
{"title":"Complications in nail surgery and prevention strategies: a comprehensive review.","authors":"Anna Bolzon, Bertrand Richert, Giuseppe Emilio Cannata, Andrea Sechi","doi":"10.4081/dr.2025.10216","DOIUrl":"10.4081/dr.2025.10216","url":null,"abstract":"<p><p>Nail surgery, commonly performed to manage a wide range of nail disorders, is associated with potential complications that can affect patients' recovery and outcomes. This review provides a detailed overview of these possible complications and strategies for their prevention. Surgical complications in nail procedures can be classified into specific and non-specific. Specific complications are associated with damage to particular structures of the nail unit, such as the matrix, nail bed, or hyponychium. Non-specific complications, such as hematoma, infection, and necrosis, may be a consequence of any surgical procedure and are not directly related to the anatomical structures involved in the operation. Recognizing factors that can contribute to these complications, such as the choice of surgical techniques, patient comorbidity management, and the implementation of postoperative care practices, is essential to reduce their incidence. This work reports the current evidence and best practices in order to reduce surgical risks and improve patient outcomes. Examining each complication and its prevention strategies in detail, this review is a practical resource for clinicians who manage nail surgery cases.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-life effectiveness of narrowband UVB phototherapy for pityriasis lichenoides. 窄带UVB光疗治疗地衣癣的临床疗效：回顾性研究。
IF 1.3
Dermatology Reports Pub Date : 2025-08-22 Epub Date: 2025-02-27 DOI: 10.4081/dr.2025.10272
Rachele Bardelli, Francesco Bellinato, Andrea Carugno, Nicola Zerbinati, Paolo Gisondi, Giampiero Girolomoni
{"title":"Real-life effectiveness of narrowband UVB phototherapy for pityriasis lichenoides.","authors":"Rachele Bardelli, Francesco Bellinato, Andrea Carugno, Nicola Zerbinati, Paolo Gisondi, Giampiero Girolomoni","doi":"10.4081/dr.2025.10272","DOIUrl":"10.4081/dr.2025.10272","url":null,"abstract":"<p><p>Dear Editor, Pityriasis lichenoides (PL) is an inflammatory skin disease of unknown etiology. The clinical spectrum of pityriasis lichenoides encompasses febrile ulcer-necrotic Mucha-Habermann disease (FUMHD), pityriasis lichenoides et varioliformis acuta (PLEVA), and pityriasis lichenoides chronica (PLC). Phototherapy is an effective and well-tolerated modality that is often successful for persistent PL or resistant to topical treatments. [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Venous thromboembolism in bullous pemphigoid: current evidence from an updated systematic review. 大疱性类天疱疮的静脉血栓栓塞：目前的证据和系统评价的更新。
IF 1.3
Dermatology Reports Pub Date : 2025-08-22 Epub Date: 2025-01-29 DOI: 10.4081/dr.2025.10257
Atheer G Almutairi, Abeer G Almutairi, Rahaf R Almutairi, Asem Shadid, Alhanouf A Bin Dakhil, Lamia Alakrash
{"title":"Venous thromboembolism in bullous pemphigoid: current evidence from an updated systematic review.","authors":"Atheer G Almutairi, Abeer G Almutairi, Rahaf R Almutairi, Asem Shadid, Alhanouf A Bin Dakhil, Lamia Alakrash","doi":"10.4081/dr.2025.10257","DOIUrl":"10.4081/dr.2025.10257","url":null,"abstract":"<p><p>Various studies have shown that individuals with bullous pemphigoid (BP) are more likely to develop venous thromboembolism (VTE). However, it is important to acknowledge that these studies primarily focused on individuals in Western nations, which restricts their generalization to a wider demographic. The present systematic review aims to assess the cumulative risk of VTE in individuals with BP compared to healthy individuals. PubMed, Cochrane, and Scopus databases were searched for evidence-based research papers on BP and VTE. Eligibility criteria were based on the PICOS criteria (population, intervention, comparison, outcome, and study design). The Newcastle-Ottawa scale assessed methodological quality. After database searches, 115 studies meeting the inclusion criteria were identified. A manual inquiry yielded an additional 11 articles. After removing duplicates (n=54), 72 publications underwent title and abstract evaluation, resulting in the exclusion of 44 manuscripts. Consequently, the remaining full-text articles were thoroughly reviewed, and ultimately, 9 publications were included. The studies were conducted in Denmark, the USA, the UK, Taiwan, and Italy. The findings enhanced the generalizability of the correlation between VTE and BP. Individuals with systemic autoimmune diseases were found to have a 1.5 to 4 times higher likelihood of developing VTE. The analysis revealed that patients with pemphigus face a twofold higher risk of VTE, especially within the first few years after diagnosis. These results may enhance the recognition of pulmonary embolism in BP patients and motivate the prevention of secondary risk markers associated with VTE. Given the morbidity, the VTE risk in BP patients warrants greater attention in public healthcare.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The efficacy and safety of microneedling combined with tacrolimus versus tacrolimus monotherapy for vitiligo treatment: a systematic review and meta-analysis. 微针联合他克莫司与他克莫司单药治疗白癜风的疗效和安全性：一项系统评价和荟萃分析。
IF 1.3
Dermatology Reports Pub Date : 2025-08-22 Epub Date: 2025-02-21 DOI: 10.4081/dr.2025.10166
Hadeel A Maaddawi, Abdulaziz A Aljuaid, Awadh M Alamri, Dhaifallah H Alghowairi, Abdullah S Bawazeer
{"title":"The efficacy and safety of microneedling combined with tacrolimus <i>versus</i> tacrolimus monotherapy for vitiligo treatment: a systematic review and meta-analysis.","authors":"Hadeel A Maaddawi, Abdulaziz A Aljuaid, Awadh M Alamri, Dhaifallah H Alghowairi, Abdullah S Bawazeer","doi":"10.4081/dr.2025.10166","DOIUrl":"10.4081/dr.2025.10166","url":null,"abstract":"<p><p>Tacrolimus is a topical immunomodulator that has been used successfully in treating vitiligo; however, recent studies suggested that combining tacrolimus with microneedling (Mn) can increase its efficacy. This systematic review aimed to assess the efficacy and safety of Mn combined with tacrolimus to treat localized and stable nonsegmental vitiligo. We searched Medline, Embase, and Cochrane Central Register of Controlled Trials (CENTRAL). The risk ratio (RR) was used to represent dichotomous outcomes, whereas the odds ratio (OR) was used for adverse events. Three randomized control trials (RCTs) (n=148 participants) were deemed eligible. The pooled effect estimate showed a statistically significant higher re-pigmentation rate in all assessed body areas in favor of treatment with Mn combined with tacrolimus (RR=2.02, 95% confidence interval [CI]: 1.51-2.70). Nonetheless, no significant difference was found between Mn combined with tacrolimus and tacrolimus monotherapy in terms of 5-grade repigmentation scale (RR=0.93, 95% CI: 0.53-1.62), histopathological assessment (RR=0.90, 95% CI: 0.47-1.75), and adverse events (OR=1.72, 95% CI: 0.10-29.36). Mn combined with tacrolimus showed a clinically and statistically substantial improvement in the re-pigmentation of vitiligo sites with acceptable tolerability and safety profile.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutaneous manifestations associated with unknown HIV infection: a case report. 与未知HIV感染相关的皮肤表现：1例报告。
IF 1.3
Dermatology Reports Pub Date : 2025-08-22 Epub Date: 2025-01-27 DOI: 10.4081/dr.2025.10178
Paolo Iacovelli, Flavia Pigliacelli, Maria Mariano, Norma Cameli, Amalia Giglio, Alessia Pacifico, Laura Gianserra, Alessandra Latini, Christof Stingone
{"title":"Cutaneous manifestations associated with unknown HIV infection: a case report.","authors":"Paolo Iacovelli, Flavia Pigliacelli, Maria Mariano, Norma Cameli, Amalia Giglio, Alessia Pacifico, Laura Gianserra, Alessandra Latini, Christof Stingone","doi":"10.4081/dr.2025.10178","DOIUrl":"10.4081/dr.2025.10178","url":null,"abstract":"<p><p>Cutaneous manifestations are extremely common in people living with human immunodeficiency virus (PLHIV), and sometimes, these manifestations can help with the diagnosis. In the advanced stages of the infection, the impairment of the immune system can increase susceptibility to cutaneous infections. We present the case of a patient affected by an unknown advanced human immunodeficiency virus (HIV) infection whose diagnosis was made through skin manifestations.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145032892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The tongue: a bridge between physiology and disorder. 舌头：生理和失调之间的桥梁。
IF 1.3
Dermatology Reports Pub Date : 2025-08-22 Epub Date: 2025-02-07 DOI: 10.4081/dr.2025.10262
Sabrine Nsir, Ghada Bouslama, Fadwa Ghanmi, Hanen Boukhris, Lamia Oualha, Souha Ben Youssef
{"title":"The tongue: a bridge between physiology and disorder.","authors":"Sabrine Nsir, Ghada Bouslama, Fadwa Ghanmi, Hanen Boukhris, Lamia Oualha, Souha Ben Youssef","doi":"10.4081/dr.2025.10262","DOIUrl":"10.4081/dr.2025.10262","url":null,"abstract":"<p><p>The tongue, as a multifunctional organ, exhibits a variety of physiological characteristics and pathological alterations. Identifying and understanding these variations is crucial for ensuring an accurate diagnosis and appropriate management. This article explores the main common physiological variations, such as geographic tongue, fissured tongue, etc., as well as pathological conditions, including elementary lesions such as vesicles, bullae, erosions, ulcers, plaques, along with surface changes (atrophy), color changes (coatings, pigmentation), or even shape alterations (infiltrations). It discusses current diagnostic tools and therapeutic approaches while emphasizing the importance of regular monitoring to prevent complications and maintain optimal oral health.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12448052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Purpuric pityriasis rosea in patients with anorexia nervosa. 紫癜性糠疹多发于神经性厌食症患者。
IF 1.3
Dermatology Reports Pub Date : 2025-08-22 Epub Date: 2025-01-20 DOI: 10.4081/dr.2025.10053
Giulia Ciccarese, Antonio Guadagno, Astrid Herzum, Valentina Amicarelli, Francesco Drago
{"title":"Purpuric pityriasis rosea in patients with anorexia nervosa.","authors":"Giulia Ciccarese, Antonio Guadagno, Astrid Herzum, Valentina Amicarelli, Francesco Drago","doi":"10.4081/dr.2025.10053","DOIUrl":"10.4081/dr.2025.10053","url":null,"abstract":"<p><p>Pityriasis rosea (PR) is an exanthematous disease associated with the endogenous systemic reactivation of human herpesvirus (HHV)-6 and/or HHV-7. Variants of PR characterized by atypical lesion morphology, eruption course, and severe symptoms have already been described, but their prevalence is probably underestimated. We report herein two patients suffering from anorexia nervosa (AN) who developed a very rare form of purpuric PR. So far, no cases of PR in AN patients have been reported in the literature.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Localized variant of junctional epidermolysis bullosa with R795X mutation. 伴有R795X突变的大疱性结缔组织表皮松解的局部变异。
IF 1.3
Dermatology Reports Pub Date : 2025-08-22 Epub Date: 2025-01-08 DOI: 10.4081/dr.2025.10127
Stefano Bighetti, Luca Bettolini, Sara Rovaris, Antonio Novelli, Paolo Incardona, Piergiacomo Calzavara-Pinton, Simone Caravello, Vincenzo Maione
{"title":"Localized variant of junctional epidermolysis bullosa with R795X mutation.","authors":"Stefano Bighetti, Luca Bettolini, Sara Rovaris, Antonio Novelli, Paolo Incardona, Piergiacomo Calzavara-Pinton, Simone Caravello, Vincenzo Maione","doi":"10.4081/dr.2025.10127","DOIUrl":"10.4081/dr.2025.10127","url":null,"abstract":"<p><p>Epidermolysis bullosa (EB) refers to a group of inherited disorders characterized by skin and mucous membrane fragility. This report presents the case of a 61-year-old Italian male with a localized variant of junctional epidermolysis bullosa (JEB) linked to the R795X mutation in the COL17A1 gene. The patient presented with bullous lesions, erosions, scars, and pigmentary changes on the pretibial areas and dystrophic nails. Genetic analysis confirmed the presence of the COL17A1 variant p.Arg795Ter (R795X) mutation, establishing a rare, localized variant of JEB. This case underscores the criticality of early and accurate diagnosis in the management of rare genetic disorders, as misdiagnosis can lead to ineffective treatments.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144946117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel therapeutic approach for loxoscelism: efficacy of cefixime and netilmicin sulfate combination therapy. 头孢克肟与硫酸奈替米星联合治疗斜交症的疗效观察。
IF 1.3
Dermatology Reports Pub Date : 2025-08-22 Epub Date: 2025-02-28 DOI: 10.4081/dr.2025.10215
Caterina Mariarosaria Giorgio, Gaetano Licata, Vittorio Tancredi, Paolino Franzese, Nicola Maria Giorgio, Giuseppe Argenziano, Eugenia Veronica Di Brizzi
{"title":"Novel therapeutic approach for loxoscelism: efficacy of cefixime and netilmicin sulfate combination therapy.","authors":"Caterina Mariarosaria Giorgio, Gaetano Licata, Vittorio Tancredi, Paolino Franzese, Nicola Maria Giorgio, Giuseppe Argenziano, Eugenia Veronica Di Brizzi","doi":"10.4081/dr.2025.10215","DOIUrl":"10.4081/dr.2025.10215","url":null,"abstract":"<p><p>Dear Editor, Loxoscelism, resulting from bites by Loxosceles spiders - particularly Loxosceles reclusa - is characterized by necrotic skin lesions and, in severe cases, systemic symptoms such as hemolysis, acute renal failure, and disseminated intravascular coagulation (DIC). [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Generalized bullous drug eruption triggered by ceftriaxone: a case report and literature overview. 头孢曲松引起全身大疱性药疹1例并文献综述。
IF 1.3
Dermatology Reports Pub Date : 2025-08-22 Epub Date: 2025-02-25 DOI: 10.4081/dr.2025.10208
Khuzama Alfalah, Khalid Nabil Nagshabandi, Hala Abdullah Almusa
{"title":"Generalized bullous drug eruption triggered by ceftriaxone: a case report and literature overview.","authors":"Khuzama Alfalah, Khalid Nabil Nagshabandi, Hala Abdullah Almusa","doi":"10.4081/dr.2025.10208","DOIUrl":"10.4081/dr.2025.10208","url":null,"abstract":"<p><p>Ceftriaxone is a widely used third-generation cephalosporin antibiotic known for its efficacy and safety. However, hypersensitivity reactions, including rare cases of generalized bullous fixed drug eruption (GBFDE), have been reported. We present the case of a 68-year-old female with a history of multiple comorbidities who developed a generalized bullous drug eruption two days after initiating intravenous ceftriaxone for a suspected respiratory infection. Clinical evaluation revealed extensive bullae and erythematous patches sparing mucous membranes, with histopathology confirming drug-induced epidermal changes. Direct immunofluorescence ruled out autoimmune bullous disorders. Prompt discontinuation of ceftriaxone, systemic corticosteroids, and supportive topical treatments led to marked clinical improvement. This case underscores the importance of recognizing rare but severe cutaneous reactions to ceftriaxone. Early diagnosis and intervention are crucial to minimizing complications and ensuring favorable outcomes.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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