{"title":"Lucio phenomenon: a case report on an overlooked reaction in lepromatous leprosy.","authors":"Natsuda Sajjachareonpong, Poonnawis Sudtikoonaseth, Kowit Kampirapap, Monton Tanabodee, Sutsarun Prunglumpoo, Chanisa Kiatsurayanon","doi":"10.4081/dr.2025.10173","DOIUrl":"https://doi.org/10.4081/dr.2025.10173","url":null,"abstract":"<p><p>Our patient presented with a 5-year history of chronic, asymptomatic papulonodular lesions on the extremities. The lesions spread to the face and earlobes, with new ulcerative lesions on both legs for the past 8 months. Skin biopsy was compatible with lepromatous leprosy with Lucio phenomenon. Lucio phenomenon is a rare type of leprosy reaction found mostly in neglected lepromatous leprosy cases. Unfortunately, the patient developed pulmonary embolism and passed away. This case report focuses on the clinicopathological characteristics and management of Lucio phenomenon, which is an unusual form of leprosy reaction that often carries a poorer prognosis. Importantly, physicians should be able to differentiate Lucio phenomenon from other types of leprosy reactions for prompt management.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The tongue: a bridge between physiology and disorder.","authors":"Sabrine Nsir, Ghada Bouslama, Fadwa Ghanmi, Hanen Boukhris, Lamia Oualha, Souha Ben Youssef","doi":"10.4081/dr.2025.10262","DOIUrl":"https://doi.org/10.4081/dr.2025.10262","url":null,"abstract":"<p><p>The tongue, as a multifunctional organ, exhibits a variety of physiological characteristics as well as pathological alterations. Identifying and understanding these variations is crucial for ensuring an accurate diagnosis and appropriate management. This article explores the main common physiological variations, such as geographic tongue, fissured tongue, etc., as well as pathological conditions, including elementary lesions such as vesicles, bullae, erosions, ulcers, plaques, as well as surface changes (atrophy), color changes (coatings, pigmentation), or even shape alterations (infiltrations). It discusses current diagnostic tools and therapeutic approaches while emphasizing the importance of regular monitoring to prevent complications and maintain optimal oral health.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dermatology ReportsPub Date : 2025-02-06Epub Date: 2024-10-25DOI: 10.4081/dr.2024.10016
Giulia Bernante, Alessandro Portoghese, Mario Lando, Barbara Ferrari, Camilla Reggiani, Raimondo Feminò, Chiara Fiorentini, Cristina Magnoni
{"title":"Reconstruction of hand surgical wounds after pseudo-syndactyly correction or squamous cell carcinoma resection in patients affected from epidermolysis bullosa: a monocentric experience with a collagen-elastin dermal matrix substitute.","authors":"Giulia Bernante, Alessandro Portoghese, Mario Lando, Barbara Ferrari, Camilla Reggiani, Raimondo Feminò, Chiara Fiorentini, Cristina Magnoni","doi":"10.4081/dr.2024.10016","DOIUrl":"10.4081/dr.2024.10016","url":null,"abstract":"<p><p>In patients with epidermolysis bullosa (EB), surgery may be required to remove squamous cell carcinoma (SCC) of the hands or to correct pseudo-syndactyly. Dermal substitutes may represent a suitable tool to promote the healing of surgical wounds in EB. We review our experience with a collagen-elastin dermal matrix to promote surgical wound healing due to hand surgery to correct pseudo-syndactyly or SCC resection in patients affected by EB. Overall, 12 patients (mean age, 29±11 years, range 13-51; four females) with EB were considered, with a total of 25 different interventions (16 SCC removals; 3 amputations for recurrent infiltrating SCC; 6 pseudo-syndactyly corrections). All patients received a collagen-elastin dermal matrix sheet. Neodermis was achieved in all patients, and no adverse events potentially associated with the graft occurred. No SCC recurrence was reported at sites operated for either SCC resection or amputation. The opening of the first or second commissure appears to be maintained for over 1 year after the procedure, preserving digital function. We believe that the application of a dermal substitute, together with a close dressing protocol, may represent a suitable strategy for obtaining physiological tissue regeneration and maintaining proper hand function in patients with EB.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11956553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scabies clinically diagnosed with eosine 2% magnification dermoscopy.","authors":"Giulio Cortonesi, Emanuele Trovato, Corinne Orsini, Elisa Cinotti, Eugenio Capalbo, Vittoria Cioppa","doi":"10.4081/dr.2024.10099","DOIUrl":"10.4081/dr.2024.10099","url":null,"abstract":"<p><p>Dear Editor, The diagnosis of scabies is primarily clinical; however, the variability in presentation can complicate it. Besides dermoscopy, different non-invasive imaging techniques have been used to assist in scabies diagnosis: 400x magnification, line-field confocal optical coherence tomography (LC-OCT), reflectance confocal microscopy (RCM), and high-frequency ultrasound (HFUS) could be useful for the diagnosis of various diseases such as benign tumors, malignant tumors, and infectious diseases of all types (viral, bacterial, and parasitic). On the other hand, all these techniques are strictly operator- and device-dependent. [...].</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epidemiological and clinical profiles of cutaneous leishmaniasis cases in Amhara National Regional State, Northwest Ethiopia: a multicenter retrospective study.","authors":"Bizuayehu Gashaw, Endalew Yizengaw, Endalkachew Nibret, Addisu Workineh, Adisu Abebe","doi":"10.4081/dr.2024.10089","DOIUrl":"10.4081/dr.2024.10089","url":null,"abstract":"<p><p>Cutaneous leishmaniasis (CL) is caused by Leishmania parasites. Ethiopia is one of the top ten countries with a high CL load, and Amhara National Regional State (ANRS) is one of the CL hotspot areas in the country. This study examined cutaneous leishmaniasis's epidemiology and clinical profiles in the ANRS region. It was conducted from April to October 2023 across eight Leishmaniasis Treatment Centres (LTCs). A data review was done from patients presenting to these centers between June 2018 and July 2023. Chi-square test and logistic regression were performed using SPSS-23. A total of 1729 patients with CL were recorded, resulting in an overall burden of 8.6 cases per 10,000 outpatients. Patients were from 112 districts, and most of them (71.1%) presented with localized cutaneous leishmaniasis (LCL). Approximately 12% of patients lived with the disease for over a year without treatment, while 13.2% of patients were multiple-time comers. Cutaneous leishmaniasis continues to be a significant public health issue in the ANRS region. Approximately onethird of CL patients exhibit the mucocutaneous leishmaniasis (MCL) clinical form. There has been a notable delay among CL patients in seeking diagnosis and treatment. It is essential to conduct large-scale community-based studies and studies focused on both traditional and modern treatment centers to accurately estimate the prevalence of CL in the region. Follow-up and molecular studies are crucial for enhancing our understanding of the clinical features of the disease. Furthermore, raising community awareness about CL prevention and control can help patients obtain early diagnosis and treatment.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A rare case of unilateral nevoid telangiectasia in a Saudi pediatric patient.","authors":"Almuntsrbellah Almudimeegh, Khalid Nabil Nagshabandi, Maee Barakeh, Turky Alsehli","doi":"10.4081/dr.2024.10091","DOIUrl":"10.4081/dr.2024.10091","url":null,"abstract":"<p><p>Unilateral nevoid telangiectasia (UNT) is a rare congenital or acquired benign cutaneous vascular anomaly first identified by Blaschko in 1899. It is characterized by superficial telangiectasias with a reticular or linear pattern on one side of the body, often following a dermatomal distribution. We present the first case of UNT documented in Saudi Arabia in a 12-year-old girl.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11904768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lichen planus pigmentosus inversus: case report and systematic review.","authors":"Fabio Massimo Gavazzoni, Federico Patta, Carla Nobile, Ilaria Girolami","doi":"10.4081/dr.2024.10000","DOIUrl":"10.4081/dr.2024.10000","url":null,"abstract":"<p><p>Lichen planus pigmentosus inversus (LPPI) is a rare variant of lichen planus characterized by well-demarcated, often slight pruritic, dark-gray plaques in intertriginous zones, hence the attribute of \"inversus\". It was originally described by Pock et al. in 2001, and less than 100 cases have been reported to date. Here, we present a case of a 52-year-old male with a two-month duration of gray-brownish plaques in bilateral axillary, submammary, antecubital, and inguinal folds. No triggering agent was present, and the biopsy showed an interface/lichenoid dermatitis with plenty of pigment incontinence. Topical tacrolimus 0.1% ointment was administered with moderate improvement at five weeks. A review of the literature showed no significant differences in involved sites and age distribution among genders, with a slightly longer duration of manifestations in females. The most administered therapeutic agents were topical corticosteroids, alone or in combination with other agents, and tacrolimus.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dermatology ReportsPub Date : 2025-02-06Epub Date: 2024-09-12DOI: 10.4081/dr.2024.10034
Čedomir Vasić
{"title":"Facial wrinkle categorization using convolutional neural network.","authors":"Čedomir Vasić","doi":"10.4081/dr.2024.10034","DOIUrl":"10.4081/dr.2024.10034","url":null,"abstract":"<p><p>A tool for detecting and classifying wrinkles on the facial skin is always welcomed in the pursuit of tight and beautiful skin. If this tool involves using a state-of-the-art neural network and high-quality images, it is highly likely to be practical. Five thousand and ninety-eight images were categorized into four classes by a trained expert and prepared for neural network training. The task was to determine whether such prepared data could serve as good material for learning and whether they could provide sufficiently high accuracy in prediction. It was found that the answer to this question is positive.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11904767/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dermatology ReportsPub Date : 2025-02-06Epub Date: 2024-10-15DOI: 10.4081/dr.2024.10067
Riccardo Cavalli, Nicola Adriano Monzani, Italo Francesco Aromolo
{"title":"Treatment of keloids with pulsed dye laser in a pediatric population.","authors":"Riccardo Cavalli, Nicola Adriano Monzani, Italo Francesco Aromolo","doi":"10.4081/dr.2024.10067","DOIUrl":"10.4081/dr.2024.10067","url":null,"abstract":"<p><p>Several studies confirmed the role of pulsed dye laser (PDL) in successfully treating keloids. To our knowledge, this is the first study conducted entirely in children (<14 years old). Case notes and photographic records of 16 pediatric patients with keloids treated with PDL at our center between 2012 and 2019 were reviewed. The red tone of the lesion before the first treatment, number of sessions, clinical improvement, and the evaluation of the satisfaction of patients have been reported. An excellent clearance has been achieved in 7 out of 16 (43.8%) cases, a good-moderate clearance in 7 patients (43.8%), and a slight clearance in 2 patients (12.4%). No patients detected absent or low results. A total of 13 out of 16 patients (81.2%) were satisfied. Lesions with higher red-tone grades could benefit from multiple treatment sessions. PDL is an effective treatment of keloids in the pediatric population, characterized by a good safety profile and high satisfaction. We observed good results treating the active remodeling lesions with a higher red tone. These data need to be confirmed with further studies in a larger set of pediatric patients.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dermatology ReportsPub Date : 2025-02-06Epub Date: 2024-10-01DOI: 10.4081/dr.2024.10077
Benedetta Sonego, Enrico Zelin, Serena Bonin, Tommaso Pozzebon, Giulia Bazzacco, Andrea Corio, Marina Agozzino, Dante Raffaele Caro Caposiena, Iris Zalaudek, Nicola Di Meo
{"title":"Calcipotriol as a daylight photodynamic therapy enhancer: a case-control study.","authors":"Benedetta Sonego, Enrico Zelin, Serena Bonin, Tommaso Pozzebon, Giulia Bazzacco, Andrea Corio, Marina Agozzino, Dante Raffaele Caro Caposiena, Iris Zalaudek, Nicola Di Meo","doi":"10.4081/dr.2024.10077","DOIUrl":"10.4081/dr.2024.10077","url":null,"abstract":"<p><p>Actinic keratoses (AKs) are common skin lesions found on sun-exposed areas and are considered potential precursors to squamous cell carcinomas (SCCs). This observational case-control study evaluates the efficacy of combining traditional daylight photodynamic therapy (DL-PDT) with pre-treatment using 0.005% calcipotriol (CAL) ointment. Twenty immunocompetent male patients with grade I-II AKs on the scalp and/or face were randomized into two groups: the case group received a 14-day pre-treatment with CAL ointment before DL-PDT, while the control group used a moisturizing cream. Both groups underwent a series of three DL-PDT sessions. The study utilized the Actinic Keratosis Area Severity Index (AKASI) scoring system to measure the actinic damage at baseline, 3 months, and 6 months post-treatment. Results showed a significant reduction in AKASI scores in the CAL group compared to controls, indicating that CAL pretreatment enhances the efficacy of DL-PDT. This combination treatment was well tolerated, with minimal discomfort reported. The findings suggest that incorporating CAL into the treatment regimen can improve the clearance of AKs and potentially prevent their progression to SCCs.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11956547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}