Dermatology Reports最新文献_第10页

IF 2.3

Dermatology Reports Pub Date : 2025-05-23 Epub Date: 2024-10-16 DOI: 10.4081/dr.2024.10086

Anna Dattolo, Francesca Sampogna, Simona Mastroeni, Luca Fania, Davide Ciccone, Damiano Abeni

{"title":"Health-related quality of life and clinical characteristics of hidradenitis suppurativa in a pediatric population.","authors":"Anna Dattolo, Francesca Sampogna, Simona Mastroeni, Luca Fania, Davide Ciccone, Damiano Abeni","doi":"10.4081/dr.2024.10086","DOIUrl":"10.4081/dr.2024.10086","url":null,"abstract":"Hidradenitis suppurativa (HS) is a chronic, skin-immunemediated inflammatory disease (sIMID), with a high impact on quality of life (QoL). Data on clinical management, comorbidities, psychosocial burden, and psychiatric disorders in pediatric patients with HS are scarce. The aim of our study was to compare clinical characteristics and patient-reported outcome measures (PROMs) for health-related quality of life (HRQoL) in adult and pediatric patients with HS. Data were collected on 601 patients with HS, 60 of whom (10.0%) were pediatric. The psychological and HRQoL impact was generally higher in adults than children, but it was also noteworthy in pediatric patients. Early diagnosis and interventions based on education for the patients and their families and psychological support are the key to optimal disease management and adherence. Our study underlines the need for screening for HS-associated psychiatric disorders and for using age-specific tools to evaluate HRQoL. A multidisciplinary approach involving several specialists is needed, as well as liaison with primary care specialists to improve care and management of comorbidities and psychological issues in patients with HS.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 2","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12172423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stevens-Johnson syndrome/toxic epidermal necrolysis induced by lamotrigine in a patient with a cerebral cavernous malformation: a case report. 拉莫三嗪致脑海绵状血管瘤患者Stevens-Johnson综合征/TEN 1例

IF 2.3

Dermatology Reports Pub Date : 2025-05-23 Epub Date: 2024-12-10 DOI: 10.4081/dr.2024.10007

Chiara Frattini, Alberto Corrà, Elena Biancamaria Mariotti, Cristina Aimo, Valentina Ruffo di Calabria, Alessandro Magnatta, Simone Landini, Lavinia Quintarelli, Alice Verdelli, Marzia Caproni

引用次数: 0

Cutaneous mastocytosis: diagnostic challenges and dietary influences. 皮肤肥大细胞增多症：诊断挑战和饮食影响。

IF 2.3

Dermatology Reports Pub Date : 2025-05-23 Epub Date: 2024-10-23 DOI: 10.4081/dr.2024.10143

Lina Al-Soufi, Aya Marashli, Rahaf Chukri HajBakri, Zuheir Al-Shehabi

引用次数: 0

Call for regulation of social media health content: an initiative of the Italian Association of Hospital Dermatologists (ADOI). 呼吁对社交媒体健康内容进行监管：意大利医院皮肤科医生协会（ADOI）的一项倡议。

IF 2.3

Dermatology Reports Pub Date : 2025-05-23 Epub Date: 2024-11-08 DOI: 10.4081/dr.2024.10169

Fortunato Cassalia, Andrea Danese, Carmine D'Acunto, Antonio Russo, Corrado Zengarini, Ignazio Stanganelli, Francesco Cusano, Fabrizio Fantini, Salvatore Amato, Davide Melandri, Cesare Massone, Anna Belloni Fortina

引用次数: 0

Rilzabrutinib-induced transition from pemphigus vulgaris to pemphigus foliaceous: a case report and literature review. 利扎布替尼诱导的寻常型天疱疮向叶状天疱疮的转变：1例报告并文献复习。

IF 2.3

Dermatology Reports Pub Date : 2025-05-23 Epub Date: 2024-10-23 DOI: 10.4081/dr.2024.10010

Christian Ciolfi, Jacopo Tartaglia, Francesca Pampaloni, Laura Fagotto, Andrea Sechi, Mauro Alaibac

{"title":"Rilzabrutinib-induced transition from pemphigus vulgaris to pemphigus foliaceous: a case report and literature review.","authors":"Christian Ciolfi, Jacopo Tartaglia, Francesca Pampaloni, Laura Fagotto, Andrea Sechi, Mauro Alaibac","doi":"10.4081/dr.2024.10010","DOIUrl":"10.4081/dr.2024.10010","url":null,"abstract":"The discovery of the role of Bruton's Tyrosine Kinase (BTK) in inflammation and autoimmunity has recently led to the development of BTK inhibitors for the treatment of autoimmune diseases, including pemphigus vulgaris. We herein present the case of a patient affected by pemphigus vulgaris, refractory to conventional immunosuppressive therapies and to multiple courses of rituximab, who was treated with rilzabrutinib and achieved disease control, but whose immunological profile switched from pemphigus vulgaris to pemphigus foliaceus after drug discontinuation. Furthermore, we reviewed the literature to better characterize the phenotypic transitions from pemphigus vulgaris to pemphigus foliaceus reported so far. The factors underlying this transition are largely unknown, although it has been postulated that immunosuppressive therapies may be more effective against anti-desmoglein 3 (DSG3) antibodies compared to anti-desmoglein 1 (DSG1). However, further studies are needed to clearly define the effect of rilzabrutinib (and immunosuppressive therapies in general) on anti-DSG1 and anti-DSG3 antibodies.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"17 2","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12264718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A large unilateral basal cell carcinoma treated with Hedgehog inhibitor sonidegib: a case report. 刺猬蛋白抑制剂sonidegib治疗1例单侧基底细胞癌。

IF 2.3

Dermatology Reports Pub Date : 2025-05-23 Epub Date: 2024-11-20 DOI: 10.4081/dr.2024.10152

Maria Alessandra Mattioli, Valentina Benzecry, Giulia Murgia, Nerina Denaro, Angelo Valerio Marzano, Emanuela Passoni, Gianluca Nazzaro

引用次数: 0

Lack of communication between dermatologists and histopathologists in real-life settings: a survey of the Italian Association of Hospital Dermatologists (ADOI). 在现实生活中，皮肤科医生和组织病理学家之间缺乏沟通：意大利医院皮肤科医生协会（ADOI）的一项调查。

IF 2.3

Dermatology Reports Pub Date : 2025-05-23 Epub Date: 2024-12-05 DOI: 10.4081/dr.2024.10084

Francesca Magri, Luca Fania, Tonia Samela, Francesco Ricci, Giovanni Di Lella, Angelo Massimiliano D'Erme, Giovanna Galdo, Francesco Cusano, Antonio Perasole, Damiano Abeni, Luigi Naldi, Cesare Massone

{"title":"Lack of communication between dermatologists and histopathologists in real-life settings: a survey of the Italian Association of Hospital Dermatologists (ADOI).","authors":"Francesca Magri, Luca Fania, Tonia Samela, Francesco Ricci, Giovanni Di Lella, Angelo Massimiliano D'Erme, Giovanna Galdo, Francesco Cusano, Antonio Perasole, Damiano Abeni, Luigi Naldi, Cesare Massone","doi":"10.4081/dr.2024.10084","DOIUrl":"10.4081/dr.2024.10084","url":null,"abstract":"Skin cancer incidence is increasing worldwide. Clear communication between dermatologists and histopathologists, along with the possibility of sharing clinical images, is critically important. This survey aims to depict the level of communication between dermatologists and histopathologists in clinical practice in Italy. A group of histopathologists participating in monthly online meetings was recruited to participate in our survey. We collected information regarding dermatologists' habits in providing or not providing clinical and dermatoscopic images of melanocytic/keratinocytic lesions. A total of 63 histopathologists agreed to participate. Fewer than 15% of histopathologists receive routine clinical or dermatoscopic images from dermatologists after the surgical excision of a melanocytic lesion, while clinical and dermoscopic images of non-melanoma skin cancers (NMSC) are sent in fewer than 10% of cases. Our survey revealed that, in Italy, the communication between dermatologists and pathologists is far from being optimal.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic challenges and importance of early multidisciplinary intervention in acral melanoma: a case report. 肢端黑色素瘤的诊断挑战和早期多学科干预的重要性：一个病例报告。

IF 2.3

Dermatology Reports Pub Date : 2025-05-22 DOI: 10.4081/dr.2025.10332

Fortunato Cassalia, Paolo Del Fiore, Andrea Danese, Michele Soldà, Vincenzo Furfaro, Simone Mocellin

引用次数: 0

Retrospective multicenter study on severely dysplastic melanocytic nevi: evaluating the need for re-excision and the risk of recurrence or progression. 严重发育不良黑素细胞痣的回顾性多中心研究：评估再次切除的必要性和复发或进展的风险。

IF 2.3

Dermatology Reports Pub Date : 2025-05-22 DOI: 10.4081/dr.2025.10349

Cesare Ariasi, Carlo Cota, Cesare Massone, Carmine D'Acunto, Pietro Danese, Maurizio Lombardo, Davide Melandri, Francesca Scarpellini, Rosa Rinaldi, Paola Pasquini, Paolo Incardona, Piergiacomo Calzavara-Pinton, Paola Monari

{"title":"Retrospective multicenter study on severely dysplastic melanocytic nevi: evaluating the need for re-excision and the risk of recurrence or progression.","authors":"Cesare Ariasi, Carlo Cota, Cesare Massone, Carmine D'Acunto, Pietro Danese, Maurizio Lombardo, Davide Melandri, Francesca Scarpellini, Rosa Rinaldi, Paola Pasquini, Paolo Incardona, Piergiacomo Calzavara-Pinton, Paola Monari","doi":"10.4081/dr.2025.10349","DOIUrl":"https://doi.org/10.4081/dr.2025.10349","url":null,"abstract":"Severely dysplastic melanocytic nevi (SMD) are histologically challenging lesions with no consensus on optimal management. While complete excision is widely recommended, the necessity of additional reexcision remains debated. This retrospective, multicenter observational cohort study evaluated the risk of recurrence and disease progression in patients with SMD by comparing those who underwent a single complete excision to those who underwent a secondary widening procedure with 5 mm margins. A total of 226 patients (230 SMD lesions) were included, with diagnoses based on the 2018 World Health Organization (WHO) criteria. Among them, 13.5% underwent re-excision despite clear margins, while 86.5% were followed clinically. Over a minimum 5-year follow-up period, no patient in either group experienced recurrence at the excision site or progression to melanoma. These findings suggest that complete excision with clear margins is sufficient for managing SMD, with no added benefit from routine re-excision. Avoiding unnecessary surgical procedures could reduce patient anxiety, healthcare costs, and surgical morbidity. Given the lack of standardized guidelines, further prospective studies are needed to refine clinical decision-making for SMD management.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urbach-Wiethe syndrome: report of two clinical cases. Urbach-Wiethe综合征：2例临床报告。

IF 2.3

Dermatology Reports Pub Date : 2025-05-20 DOI: 10.4081/dr.2025.10230

Ilaria Demofonte, Emanuele Miraglia, Giovanni Pellacani, Sandra Giustini

{"title":"Urbach-Wiethe syndrome: report of two clinical cases.","authors":"Ilaria Demofonte, Emanuele Miraglia, Giovanni Pellacani, Sandra Giustini","doi":"10.4081/dr.2025.10230","DOIUrl":"https://doi.org/10.4081/dr.2025.10230","url":null,"abstract":"Urbach-Wiethe syndrome, also known as lipoid proteinosis (LP), is a rare genodermatosis clinically characterized by mucocutaneous lesions, dysphonia with onset in early childhood, and, sometimes, neurological complications. Clinical signs, as well as the severity of the disease, are highly variable, while its course is usually slowly progressive. The typical primary sign is hoarse crying, due to laryngeal infiltration, at birth or during early childhood. Alterations of the skin and mucous membranes develop within the first two years of life. The skin lesions initially appear on the face and limbs and usually resolve by healing. Infiltration of the respiratory system can cause upper respiratory tract infections, hoarseness or aphonia, dysphagia, and even airway obstruction. Dystonia, epileptic seizures, and learning disorders may be observed in affected children. Treatment remains a major challenge since no standardized therapies exist, but oral acitretin appears to be effective in improving skin manifestations. We report two clinical cases of young women suffering from LP, presenting with dermatological, otorhinolaryngological, and neurological symptoms, currently referred to our Rare Cutaneous Syndrome Center at the Policlinico Umberto I in Rome (Italy).","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0