Dermatology Reports最新文献

{"title":"Teledermatopathology on the ADOI platform and beyond.","authors":"Cesare Massone, Antonio Perasole, Luigi Naldi","doi":"10.4081/dr.2022.9670","DOIUrl":"10.4081/dr.2022.9670","url":null,"abstract":"","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 1","pages":"9670"},"PeriodicalIF":2.3,"publicationDate":"2023-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b0/49/dr-15-1-9670.PMC10080286.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9272327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erosive pustular dermatosis of the scalp: a pathogenetic mystery and therapeutic challenge.","authors":"Georgi Tchernev,&nbsp;Simona Kordeva,&nbsp;Ilia Batashki,&nbsp;Atanas Batashki,&nbsp;Heily Kirilova,&nbsp;Konstantin Stavrov","doi":"10.4081/dr.2022.9556","DOIUrl":"https://doi.org/10.4081/dr.2022.9556","url":null,"abstract":"<p><p>Erosive pustular dermatosis of the scalp (EPD) is a rare condition that affects predominantly the adult population and occurs on a previously photo-damaged bald scalp. The physical examination is presented with large erythematous, erosive and crusted patches with granulation on an atrophic skin. The problem in patients with erosive pustular dermatosis of the scalp arises from the non-specific clinical and histopathological findings, which can be misleading. Biopsy followed by careful histopathological verification is mandatory, although the finding is nonspecific. The histopathology findings are characterized by superficial erosions with mild neutrophil infiltrate, mainly intravascular and focally with neutrophil exocytosis; focal parakeratosis, smoothed rete ridges without pronounced interface changes; pronounced lymphoplasmacytic infiltrate with focal distribution in the dermis and giant cell reaction with the formation of a \"foreign body\" granuloma.. We report a 58-year-old male patient with a 1-year-old lesion, suspected for skin cancer, later diagnosed with EPDS, which was successfully treated with topical clobetasol proprionate after 3-5weeks.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 1","pages":"9556"},"PeriodicalIF":1.1,"publicationDate":"2023-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/39/f0/dr-15-1-9556.PMC10099292.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9316853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agreement on classification of clinical photographs of pigmentary lesions: exercise after a training course with young dermatologists.","authors":"Simone Cazzaniga,&nbsp;Lucia De Ponti,&nbsp;Giorgio Maria Baratelli,&nbsp;Salvatore Francione,&nbsp;Carlo La Vecchia,&nbsp;Anna Di Landro,&nbsp;Andrea Carugno,&nbsp;Marco Di Mercurio,&nbsp;Lerica Germi,&nbsp;Giampaolo Trevisan,&nbsp;Mirko Fenaroli,&nbsp;Claudia Capasso,&nbsp;Michele Pezza,&nbsp;Pietro Dri,&nbsp;Emanuele Castelli,&nbsp;Luigi Naldi","doi":"10.4081/dr.2022.9500","DOIUrl":"https://doi.org/10.4081/dr.2022.9500","url":null,"abstract":"<p><p>Smartphone apps may help promoting the early diagnosis of melanoma. The reliability of specialist judgment on lesions should be assessed. Hereby, we evaluated the agreement of 6 young dermatologists, after a specific training. Clinical judgment was evaluated during 2 online sessions, 1 month apart, on a series of 45 pigmentary lesions. Lesions were classified as highly suspicious, suspicious, non-suspicious or not assessable. Cohen's and Fleiss' kappa were used to calculate intra- and inter-rater agreement. The overall intra-rater agreement was 0.42 (95% confidence interval - CI: 0.33-0.50), varying between 0.12-0.59 on single raters. The inter-rater agreement during the first phase was 0.29 (95% CI: 0.24-0.34). When considering the agreement for each category of judgment, kappa varied from 0.19 for not assessable to 0.48 for highly suspicious lesions. Similar results were obtained in the second exercise. The study showed a less than satisfactory agreement among young dermatologists. Our data point to the need for improving the reliability of the clinical diagnoses of melanoma especially when assessing small lesions and when dealing with thin melanomas at a population level.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 1","pages":"9500"},"PeriodicalIF":1.1,"publicationDate":"2023-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/eb/80/dr-15-1-9500.PMC10099286.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9316854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polymorphic eruption of pregnancy.","authors":"Vjosa A Zejnullahu,&nbsp;Valon A Zejnullahu","doi":"10.4081/dr.2022.9546","DOIUrl":"https://doi.org/10.4081/dr.2022.9546","url":null,"abstract":"<p><p>Polymorphic eruption of pregnancy (PEP) is a benign self-limiting dermatoses that occurs during pregnancy and/or the postpartum period. Etiology is unknown and evidence suggest a relationship between excessive maternal weight gain, cesarean deliveries, skin overdistension, multiple gestation and male fetuses. We present a case of PEP in a 26-year-old woman with twin pregnancy. We recommend prompt evaluation and diagnosis of a pregnant woman with primary skin lesions and pruritus to differentiate between the benign polymorphic eruption of pregnancy and other dermatosis which are associated with increased fetal morbidity.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 1","pages":"9546"},"PeriodicalIF":1.1,"publicationDate":"2023-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fb/b2/dr-15-1-9546.PMC10080288.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9282793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Venous wall graft in the eyelid reconstruction: observations drawn from 64 cases.","authors":"Cesare Barbera,&nbsp;Roberto Manzoni,&nbsp;Lucio Dodaro,&nbsp;Monica Ferraro,&nbsp;Paolo Pella","doi":"10.4081/dr.2022.9499","DOIUrl":"https://doi.org/10.4081/dr.2022.9499","url":null,"abstract":"<p><p>The aim of this report is to illustrate the venous wall graft and to present the observations drawn from a large series of eyelid reconstructions performed with this method. Sixty-four patients underwent venous wall grafts, mostly after resection of invasive carcinomas of the eyelids and, in only one case, after traumatic injury. All patients had good functional and cosmetic results. The average follow-up time was 6.5 years. Few negligible complications were observed. Only two cases (3.1%) needed further surgical treatment. Vein graft is a reliable alternative to traditional procedures in replacing tarsus-conjunctival layer, achieving satisfactory results. A single surgical session is required, usually without complications.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 1","pages":"9499"},"PeriodicalIF":1.1,"publicationDate":"2023-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/50/ca/dr-15-1-9499.PMC10099297.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9371271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Face mask-induced skin changes: a new common phenomenon during the coronavirus disease 2019 pandemic.","authors":"Abrar E Bukhari,&nbsp;Alhanouf A Bin Dakhil,&nbsp;Abdulrhman A Albrkheel,&nbsp;Malak M Almutlq,&nbsp;Omar K Alolayan,&nbsp;Mohammed A Alqahtani,&nbsp;Fahad S Alsubaie,&nbsp;Dana S Alessa,&nbsp;Fajer M Alzamil","doi":"10.4081/dr.2022.9526","DOIUrl":"https://doi.org/10.4081/dr.2022.9526","url":null,"abstract":"<p><p>Coronavirus disease 2019 is a severe acute respiratory syndrome, and wearing a mask is an important preventive measure. However, long-term use can cause <i>maskne</i>, or mask-induced acne. This study evaluated the prevalence, clinical characteristics, and severity of mask-induced acne and its effect on pre-existing dermatosis using an online questionnaire. The questionnaire comprised 15 questions on 6 primary topics: demographic data, type of face mask, dermatological symptoms after using a mask, preexisting dermatological conditions, the duration of use, and the effects of mask use on existing dermatological conditions. We included 1,025 participants; 48.6% had dermatological symptoms after using masks. The most common symptoms were red papules (33.8%) and itching (27.2%). Individuals who wore masks for more than 4 hours daily experienced more dermatological symptoms, for example, healthcare providers, who had a higher risk of maskrelated dermatosis than participants with other occupations. Moreover, masks significantly increased the severity of rosacea, contact dermatitis, and seborrheic dermatitis. These results suggest that board-certified dermatologists should assess patients in larger-scale studies to determine adequate management strategies.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 1","pages":"9526"},"PeriodicalIF":1.1,"publicationDate":"2023-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/32/03/dr-15-1-9526.PMC10099290.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9371269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of sweat-gland carcinoma with neuroendocrine differentiation.","authors":"Shigeru Koizumi,&nbsp;Yaei Togawa,&nbsp;Inozume Takashi,&nbsp;Michiyo Nakano","doi":"10.4081/dr.2022.9513","DOIUrl":"https://doi.org/10.4081/dr.2022.9513","url":null,"abstract":"Low-grade neuroendocrine tumors, also known as carcinoid tumors, are slow-growing cancers derived from neuroendocrine cells, usually found in the digestive tract or lung lining; the primary tumor in the skin is extremely rare and is called sweat-gland carcinoma with neuroendocrine differentiation (SCAND) as a new disease concept.1-4 Herein, we report a case of SCAND on the lower abdomen presenting bilateral inguinal lymph node metastasis. A 73-year-old Japanese male patient presented to our hospital with a 5-year history of a red nodule arising from the lower abdomen to the base of the penis. He has a medical history of hypertension, atrial fibrillation, and cerebral infarction. Physical examination revealed a red mulberryshaped nodule with red papules (Figure 1A) and enlarged, elastic, and complex lymph nodes at the bilateral inguinal region. Dermoscopy showed branched and/or partially reticular vessels on a pale red structureless area (Figure 1B). Contrastenhanced computed tomography revealed two tumors in the left kidney. They were renal cell carcinomas classified as cT1aN0M0 stage I with a low probability of metastasis, and no other visceral malignancies were found. 18F-fluorodeoxyglucose positron emission tomography integrated with computed tomography showed abnormally increased cellular uptake of glucose on the lower abdomen and bilateral inguinal lymph nodes; however, the left renal tumors and other sites showed normal uptake. Skin biopsy revealed various-sized tumor nests diffusely infiltrated from dermis to subcutaneous tissue (Figure 2A-B). Focal pagetoid extension of the tumor cells within the overlying epidermis was observed. The tumor cells were small to medium size, with abundant and pale eosinophilic cytoplasm, round-to-oval nuclei, and coarse granular chromatin pattern. Few nuclear atypia and mitotic figures were observed (Figure 2C). A tumor mass floating in abundant mucus was observed in part of the tumor (&lt;10%) (Figure 2D). Alcian blue staining (pH 2.5) showed extracellular mucin deposition. The metastatic lymph nodes were almost replaced by tumor cells that showed a trabecular growth pattern (Figure 2E). Immunohistochemical staining of the tumor cells was positive for cytokeratin 7, estrogen receptor, progesterone receptor, chromogranin A, synaptophysin, CD56, and GATA3 and negative for cytokeratin 20. Consequently, we diagnosed this tumor as SCAND. However, the scheduled surgery was canceled due to multiple cerebral infarctions. SCAND was a newly proposed entity and sporadic disease in 2022. It commonly occurs on milk-lines on the trunk of middle-aged to elderly males and often causes lymph node metastasis.4 In our case, histopathologically, a tumor mass floating in a large amount of mucus was observed in part, and primary cutaneous mucinous carcinoma (PCMC) with neuroendocrine differentiation was the differential diagnosis. However, since this feature accounts for only a tiny fraction of tumors (&lt;10%) and PCMC occurs primari","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 1","pages":"9513"},"PeriodicalIF":1.1,"publicationDate":"2023-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e7/f7/dr-15-1-9513.PMC10080290.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9641666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pityriasis rosea and pityriasis rosea-like eruption after anti-SARS-CoV-2 vaccination: a report of five cases and review of the literature.","authors":"Stefano Veraldi,&nbsp;Vinicio Boneschi,&nbsp;Marco Cusini,&nbsp;Carlo Alberto Maronese","doi":"10.4081/dr.2022.9503","DOIUrl":"https://doi.org/10.4081/dr.2022.9503","url":null,"abstract":"<p><p>Only a few cases of pityriasis rosea (PR)/pityriasis rosea-like eruption (PRLE) after anti-SARS-CoV-2 vaccination have been reported. In the period May 2021- February 2022 we observed five cases of clinically typical PR that appeared 2 to 3 weeks after anti-SARS-CoV-2 vaccination with BNT162b2 (3 patients) or mRNA- 1273 (2 patients). In 4 patients PR appeared after the first vaccination; in one patient after the second one. In 3 patients a biopsy for histopathological examinations was carried out. Results were typical for PR. In all patients laboratory examinations were within normal ranges. All patients were treated with cetirizine. Complete remission was observed within 14-30 days. Four patients were subjected to the second vaccination, but no skin lesions appeared. All patients are currently in good general health. It is possible that a relationship between anti- Sars-CoV-2 vaccination and PR/PRLE exists; however, it is very rare, in consideration of millions of vaccinated subjects and the low number of reported cases of PR/PRLE. The pathogenesis of this relationship is unknown. However, some hypotheses may be advanced: PR/PRLE following anti-Sars-CoV-2 vaccination may be just a coincidence; anti-Sars-CoV-2 vaccines cause a reactivation of HHV-6 and/or HHV-7; vaccines can induce a delayed hypersensitivity response clinically similar to drug-induced PRLE.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 1","pages":"9503"},"PeriodicalIF":1.1,"publicationDate":"2023-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/72/ff/dr-15-1-9503.PMC10099291.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9371266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eruptive basal cell carcinoma and lenalidomide: rising awareness among dermatologists.","authors":"Calogero Pagliarello,&nbsp;Carlo Renè Girardelli,&nbsp;Ignazio Stanganelli","doi":"10.4081/dr.2022.9534","DOIUrl":"https://doi.org/10.4081/dr.2022.9534","url":null,"abstract":"<p><p>Because of its higher level of safety compared to its parent medicine, thalidomide, lenalidomide (L) is chosen for the treatment of multiple myeloma. We report a patient who, within a month of using L, developed more than 10 basal cell carcinomas.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 1","pages":"9534"},"PeriodicalIF":1.1,"publicationDate":"2023-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d7/f8/dr-15-1-9534.PMC10099294.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9371272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maculopapular sarcoidosis: the importance of skin signs.","authors":"Giovanna Galdo,&nbsp;Gelsomina Luongo,&nbsp;Daniela Capacchione,&nbsp;Damiano Abeni,&nbsp;Marta Grimaldi,&nbsp;Luca Fania","doi":"10.4081/dr.2022.9561","DOIUrl":"https://doi.org/10.4081/dr.2022.9561","url":null,"abstract":"<p><p>Sarcoidosis is a multisystem disease that affects the skin in 20 to 30% of cases. Skin findings are often the initial presenting signs, and cutaneous sarcoidosis may appear with a wide variety of lesions; it is often considered an imitator of many other skin diseases. Clinical appearance and specific dermoscopic criteria, confirmed by a typical pathology, may guide to the correct diagnosis. We report the case of a man affected by maculo-papular sarcoidosis on the back, in which the detection of cutaneous lesions was the initial step to determine the systemic nature of the disease.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 1","pages":"9561"},"PeriodicalIF":1.1,"publicationDate":"2023-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d7/a2/dr-15-1-9561.PMC10086543.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9310691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}