Dermatology Reports最新文献

{"title":"A unilateral linear pattern of lichen planus pigmentosus.","authors":"Amal Aboud Alasmari,&nbsp;Latifah Ibrahim Albrahim,&nbsp;Majed Aleissa","doi":"10.4081/dr.2023.9650","DOIUrl":"10.4081/dr.2023.9650","url":null,"abstract":"<p><p>Lichen planus pigmentosus (LPP) is a rare chronic variant of lichen planus. LPP distribution tends to be symmetrical and is frequently seen on the face, neck, and trunk. Atypical clinical patterns of LPP, including segmental, zosteriform, and linear, were reported in the literature. Herein, we report a rare presentation of LPP in a 16- year-old female with a unilateral linear pattern along the Blascko lines.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 3","pages":"9650"},"PeriodicalIF":1.1,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/26/b8/dr-15-3-9650.PMC10563022.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41194359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atopic dermatitis: a brief review of recent advances in management","authors":"S. Alenazi","doi":"10.4081/dr.2023.9678","DOIUrl":"https://doi.org/10.4081/dr.2023.9678","url":null,"abstract":"Atopic dermatitis (AD) is a common inflammatory skin disorder characterised by recurrent eczematous lesions and intense itch. The disorder affects people of all ages and ethnicities, has a substantial psychosocial impact on patients and relatives, and is the leading cause of the global burden from skin disease. Atopic dermatitis is associated with an increased risk of multiple comorbidities, including food allergy, asthma, allergic rhinitis, and mental health disorders. The pathophysiology is complex and involves a strong genetic predisposition, epidermal dysfunction, and T-cell driven inflammation. Although type-2 mechanisms are dominant, there is increasing evidence that the disorder involves multiple immune pathways. Until recently, the management of AD rested mainly on the judicious use of emollients, topical steroids, and topical calcineurin inhibitors in the majority of patients and systemic immunosuppressants were advocated in severely diseased. However, in the last few years, new therapeutic strategies were designed and developed to target the various steps in the chain of molecular events that lead to the AD phenotype. This review highlights the recent advancements in the management of AD.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47936110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent giant cellulitis-like sweet syndrome induced by SARS-CoV-2 Pfizer-BioNTech mRNA vaccine","authors":"P. Hirt, Lily Park, Carly E. Wallace, F. Kerdel","doi":"10.4081/dr.2023.9668","DOIUrl":"https://doi.org/10.4081/dr.2023.9668","url":null,"abstract":"Primary and booster vaccines for COVID-19 are the most effective method of preventing infection and are generally considered safe. However, many cutaneous adverse events have been reported following vaccination. To date there have been seven reported cases of Sweet syndrome occurring following the first dose of the SARS-CoV-2 vaccine. We describe a rare case of atypical giant-cellulitis like Sweet syndrome reemerging after receiving the SARS-CoV-2 booster vaccine.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46782271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with mask-induced dermatosis and its impact on patients' quality of life.","authors":"Thuy Luong Nguyen Dac,&nbsp;Trang Vu Thi Thuy,&nbsp;Anh Le Dang Mai,&nbsp;Lien Nguyen Thi Bich,&nbsp;Tam Huynh Thi Xuan","doi":"10.4081/dr.2023.9694","DOIUrl":"10.4081/dr.2023.9694","url":null,"abstract":"<p><p>The COVID-19 pandemic continues to have a significant impact on society, both physically and mentally. Mask use in public places has been made mandatory in many countries, as it is one of the most effective methods to prevent transmission of the virus. However, continuous mask usage has been associated with the emergence of various cutaneous diseases in the areas of contact with the mask. This study aimed to evaluate the effect of various cutaneous manifestations resulting from mask use on patients' quality of life through a questionnaire survey. This was a cross-sectional study conducted at a hospital from May to July 2022. Patients who had experienced skin symptoms related to mask use in the past or present were included in the study. Participants completed the questionnaire with informed consent. A total of 165 participants participated in the survey, with the most common complaint being itching (58.18%), followed by acne (52.73%). Itching was found to have the highest dermatology life quality index score. Patients with skin redness had a lower quality of life compared to those without it. Prolonged mask-wearing can result in skin diseases that can seriously impair patients' quality of life.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 3","pages":"9694"},"PeriodicalIF":1.1,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ad/6d/dr-15-3-9694.PMC10563030.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41194363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What is the most accurate naming convention: cutaneous lipofibroma or pedunculated lipofibroma?","authors":"M. Al-Haddab","doi":"10.4081/dr.2023.9675","DOIUrl":"https://doi.org/10.4081/dr.2023.9675","url":null,"abstract":"We report a case of large pedunculated lipofibroma on left axilla in 36 year old woman, the lesion was excised completely with no recurrence after one year follow up. We propose a new name for this rare entity to be more inclusive of all lesions of pedunculated lipofibroma and to differentiate it from the other entity called fibrolipoma.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47906951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pemphigus vulgaris mimicking Steven-Johnson syndrome/toxic epidermal necrolysis: report of an unusual case.","authors":"Latifah Albrahim,&nbsp;Amal Aboud Alasmari,&nbsp;Majed Aleissa","doi":"10.4081/dr.2023.9649","DOIUrl":"10.4081/dr.2023.9649","url":null,"abstract":"<p><p>Pemphigus vulgaris (PV) is an autoimmune blistering disease affecting the skin and mucosa. It clinically presents as painful erosions, mainly in the oral cavity, and flaccid blisters and erosions on the skin. Steven-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a severe mucocutaneous drug hypersensitivity reaction characterized by painful, dusky, erythematous eruptions that often progress to blisters, erosions, and extensive epidermal detachment accompanied by systemic symptoms. Herein, we report the case of a 48-year-old man who presented with extensive skin and mucosal lesions following the ingestion of an unknown medication. The patient's symptoms clinically mimicked SJS, and accordingly, a preliminary diagnosis of SJS/TEN was made. However, clinical investigation of skin biopsy and direct immunofluorescence assay results indicated PV, and a final diagnosis of PV was established.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 3","pages":"9649"},"PeriodicalIF":1.1,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/67/aa/dr-15-3-9649.PMC10563021.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41194366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-interleukin-17 and anti-interleukin-23 biologic drugs for genital psoriasis: a single-center retrospective comparative study.","authors":"Andrea Cortese,&nbsp;Luigi Gargiulo,&nbsp;Luciano Ibba,&nbsp;Giovanni Fiorillo,&nbsp;Francesco Toso,&nbsp;Carlo Alberto Vignoli,&nbsp;Alessandra Narcisi,&nbsp;Antonio Costanzo,&nbsp;Mario Valenti","doi":"10.4081/dr.2023.9692","DOIUrl":"https://doi.org/10.4081/dr.2023.9692","url":null,"abstract":"<p><p>Genital psoriasis affects 3-33% of patients with psoriasis during the course of the disease, usually leading to a severe reduction in the patient's quality of life. This study aims to retrospectively assess the effectiveness of interleukin (IL)-23 and IL-17 inhibitors in a real-life population affected by moderate-to-severe plaque psoriasis with genital involvement coming from our dermatology department. A total of 86 patients with a diagnosis of moderate-tosevere plaque psoriasis with severe genital involvement were enrolled. Patient characteristics, psoriasis area and severity index (PASI), and static physician global assessment of genitalia (sPGAG) at each visit were recorded. During the treatment, the mean PASI decreased from 12.8 to 0.63 at week 52; a PGA of 0/1 was reached by 97.40% at week 52 and by 100% of patients (37/37) at week 104. No significant differences between IL-23 and IL-17 inhibitors were observed; indeed, the bio-naïve group of patients demonstrated a superior response compared to the group of bioexperienced patients.Our findings confirmed that IL-23 and IL-17 inhibitors are safe and effective therapeutic options for the treatment of genital psoriasis.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 3","pages":"9692"},"PeriodicalIF":1.1,"publicationDate":"2023-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/81/9b/dr-15-3-9692.PMC10543193.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41116199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report of Hailey-Hailey disease treated with fractional carbon dioxide laser","authors":"Zivile Gabdrafike, Monika Blazeviciute, Ugne Janonyte, J. Makštienė, S. Valiukevičienė","doi":"10.4081/dr.2023.9658","DOIUrl":"https://doi.org/10.4081/dr.2023.9658","url":null,"abstract":"Hailey-Hailey disease (HHD) or familial benign pemphigus is a rare genetic condition, characterized by recurrent blisters and erosions, with a predilection for intertriginous areas. There is no specific treatment for HHD. Topical and systemic treatment tends to provide temporary remission. Alternative treatment (surgical interventions, such as dermabrasion, excision, and laser) has been shown to prolong remission. Considering the risk of complications associated with surgical modalities, laser is often preferred as an alternative for patients failing to respond to first-line therapies. We report a case of recalcitrant HHD successfully treated with a fractional ablative CO2 laser procedure (wavelength of 10600 nm, power of 7-10 W, 2-3 passes) on a 35-year-old female. The patient has a seven-year history of therapy-resistant HHD. A 2-month follow-up showed substantially resolved lesions, with mild erythema and post-inflammatory hyperpigmentation in treated areas.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44324995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burnout phenomenon in Saudi dermatology residents: a national assessment of prevalence and contributing factors.","authors":"Asem M Shadid,&nbsp;Batal M Aldosari,&nbsp;Sakhr Dawari,&nbsp;Ahmed Baabdullah,&nbsp;Asma AlKheraiji,&nbsp;Abdulatif Majed AlBassam,&nbsp;Saad Altalhab,&nbsp;Ruaa Alharithy","doi":"10.4081/dr.2023.9655","DOIUrl":"10.4081/dr.2023.9655","url":null,"abstract":"<p><p>A cross-sectional study was conducted between March and August 2021; an electronic survey was administered to all dermatology residents (n=79) in all centers with the Saudi Board Dermatology Training Program in the western, eastern and southern regions. Participation was voluntary, and written informed consent was obtained before the study. The survey was completed by 70 dermatology residents, for an 88.61% response rate. All the participants were aware of the study's aims, and their informed consent was obtained. The study design complied with the Declaration of Helsinki ethical standards and was approved by the Institutional Review Board at Imam Muhammad Ibn Saud Islamic University in Saudi Arabia. A total of 70 respondents completed the questionnaire. High emotional exhaustion (EE) was present in 47.1% of respondents, low personal accomplishment (PA) was present in 65.7%, and high depersonalization (DP) was the least prevalent (24.3%) across all burnout dimensions of dermatology residents. Overall burnout was present in 21.4% of the dermatology residents. Multivariate analysis showed that the odds of EE were significantly lower in males than females [odds ratio (OR)=0.2, P=0.016] and the higher number of patients seen per clinic (OR=1.09, P=0.032) was associated with higher odds of having a high risk of EE, while higher satisfaction with work-life balance was associated with lower odds of a high risk of EE (OR=0.47, P=0.005). A higher number of study hours/week was associated with lower odds of low PA (OR=0.95, P=0.02). Similarly, higher satisfaction with career was associated with lower odds of low PA (OR=0.35, P=0.042). Multivariate analysis showed that only exercise (OR=0.21, P=0.05) and satisfaction with work-life balance (OR=0.42, P=0.008) were associated with a lower risk of burnout. Our study adds the burnout rates among dermatology residents in Saudi Arabia, in addition to possible risk factors that can predict burnout, to the literature. These findings can be applied to improve training programs and reduce the burnout rate among residents.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"15 3","pages":"9655"},"PeriodicalIF":1.1,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0c/23/dr-15-3-9655.PMC10563028.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41194361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"XXVIII Italian Melanoma Intergroup National Congress - Florence, Italy | 30 September-2 October 2022","authors":"Italian Melanoma Intergroup (IMI)","doi":"10.4081/dr.2023.9719","DOIUrl":"https://doi.org/10.4081/dr.2023.9719","url":null,"abstract":"Abstracts from the Italian Melanoma Intergroup (IMI) National Congress","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46088951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}