小儿生殖器疣成功治疗光动力疗法。

IF 1.3 Q2 DERMATOLOGY
Dermatology Reports Pub Date : 2025-05-23 Epub Date: 2024-11-04 DOI:10.4081/dr.2024.9979
Federica Li Pomi, Andrea D'Aloja, Antonio Di Tano, Mario Vaccaro, Francesco Borgia
{"title":"小儿生殖器疣成功治疗光动力疗法。","authors":"Federica Li Pomi, Andrea D'Aloja, Antonio Di Tano, Mario Vaccaro, Francesco Borgia","doi":"10.4081/dr.2024.9979","DOIUrl":null,"url":null,"abstract":"<p><p>Genital warts (GWs) are the most common sexually transmitted infections worldwide, caused by the human papillomavirus (HPV). In adults, the primary mode of transmission is through sexual contact, whereas in children, it can occur through skin-to-skin or skin-to-mucosa contact and be sexual or non-sexual. The increasing prevalence of GWs in children has renewed the interest in therapeutic management, which still presents a unique challenge, being influenced by many variables, including size, quantity, and location of warts, as well as the presence of comorbidities. Photodynamic therapy (PDT) has already shown encouraging results in treating viral warts in adult patients, but its use is still not standardized in the pediatric population. On this topic, we report the case of an otherwise healthy 5-year-old child affected by GWs, successfully treated with three sessions of PDT with 10% 5-aminolaevulinic acid (ALA) at one-month intervals. Our case is paradigmatic of the potential of PDT to treat difficult lesions in a pediatric setting.</p>","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12210356/pdf/","citationCount":"0","resultStr":"{\"title\":\"Pediatric genital warts successfully treated with photodynamic therapy.\",\"authors\":\"Federica Li Pomi, Andrea D'Aloja, Antonio Di Tano, Mario Vaccaro, Francesco Borgia\",\"doi\":\"10.4081/dr.2024.9979\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Genital warts (GWs) are the most common sexually transmitted infections worldwide, caused by the human papillomavirus (HPV). In adults, the primary mode of transmission is through sexual contact, whereas in children, it can occur through skin-to-skin or skin-to-mucosa contact and be sexual or non-sexual. The increasing prevalence of GWs in children has renewed the interest in therapeutic management, which still presents a unique challenge, being influenced by many variables, including size, quantity, and location of warts, as well as the presence of comorbidities. Photodynamic therapy (PDT) has already shown encouraging results in treating viral warts in adult patients, but its use is still not standardized in the pediatric population. On this topic, we report the case of an otherwise healthy 5-year-old child affected by GWs, successfully treated with three sessions of PDT with 10% 5-aminolaevulinic acid (ALA) at one-month intervals. Our case is paradigmatic of the potential of PDT to treat difficult lesions in a pediatric setting.</p>\",\"PeriodicalId\":11049,\"journal\":{\"name\":\"Dermatology Reports\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-05-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12210356/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dermatology Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4081/dr.2024.9979\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/11/4 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dermatology Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4081/dr.2024.9979","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/4 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

生殖器疣(GWs)是世界上最常见的性传播感染,由人类乳头瘤病毒(HPV)引起。在成人中,主要传播方式是通过性接触,而在儿童中,它可以通过皮肤对皮肤或皮肤对粘膜接触发生,并且是性或非性接触。儿童GWs患病率的增加重新引起了对治疗管理的兴趣,这仍然是一个独特的挑战,受到许多变量的影响,包括疣的大小、数量和位置,以及合并症的存在。光动力疗法(PDT)在治疗成年患者的病毒性疣方面已经显示出令人鼓舞的结果,但其在儿科人群中的应用仍未标准化。在这个主题上,我们报告了一个其他健康的5岁儿童受GWs影响的病例,成功地治疗了三个疗程的PDT与10%的5-氨基乙酰丙酸(ALA),每隔一个月。我们的病例是典型的潜力的PDT治疗困难的病变在儿科设置。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Pediatric genital warts successfully treated with photodynamic therapy.

Pediatric genital warts successfully treated with photodynamic therapy.

Genital warts (GWs) are the most common sexually transmitted infections worldwide, caused by the human papillomavirus (HPV). In adults, the primary mode of transmission is through sexual contact, whereas in children, it can occur through skin-to-skin or skin-to-mucosa contact and be sexual or non-sexual. The increasing prevalence of GWs in children has renewed the interest in therapeutic management, which still presents a unique challenge, being influenced by many variables, including size, quantity, and location of warts, as well as the presence of comorbidities. Photodynamic therapy (PDT) has already shown encouraging results in treating viral warts in adult patients, but its use is still not standardized in the pediatric population. On this topic, we report the case of an otherwise healthy 5-year-old child affected by GWs, successfully treated with three sessions of PDT with 10% 5-aminolaevulinic acid (ALA) at one-month intervals. Our case is paradigmatic of the potential of PDT to treat difficult lesions in a pediatric setting.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Dermatology Reports
Dermatology Reports DERMATOLOGY-
CiteScore
1.40
自引率
0.00%
发文量
74
审稿时长
10 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信