直线型银屑病还是ILVEN?一个儿科病例解开了拼图。

IF 1.3 Q2 DERMATOLOGY
Nicolò Rivetti, Camilla Vassallo, Stefania Barruscotti, Valeria Brazzelli, Carlo Francesco Tomasini
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引用次数: 0

摘要

线状牛皮癣样皮疹在儿童中具有诊断挑战性,特别是当他们遵循Blaschko线时。主要的鉴别诊断包括炎性线状疣状表皮痣(ILVEN)和线状银屑病(LP),这是一种罕见的马赛克变体。我们描述的情况下,一个5岁的男孩广泛的单侧病变,临床提示这两个实体。组织学显示门罗微脓肿和银屑病样增生。患者在局部应用钙化三醇/倍他米松后病情迅速好转,随后长期缓解。值得注意的是,经过8年的随访,病变仍然严格局限于原始Blaschkoid分布,没有皮外受损伤,只有轻微复发。这一临床过程有力地支持了孤立的线状银屑病(1型镶嵌病)的诊断。文献中很少有儿科病例记录了如此长期而稳定的演变,这使得本报告对LP和ILVEN的区分做出了宝贵的贡献。该病例强调了在评估儿童线性皮肤病时整合临床、组织学和纵向数据的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Linear psoriasis or ILVEN? A pediatric case unraveling the mosaic puzzle.

Linear psoriasiform eruptions in children are diagnostically challenging, particularly when they follow Blaschko's lines. The main differential diagnosis includes inflammatory linear verrucous epidermal nevus (ILVEN) and linear psoriasis (LP), a rare mosaic variant. We describe the case of a 5-year-old boy with extensive unilateral lesions clinically suggestive of both entities. Histology revealed Munro microabscesses and psoriasiform hyperplasia. The patient showed rapid improvement with topical calcipotriol/betamethasone, followed by long-term remission. Notably, after 8 years of follow-up, the lesions remained strictly confined to the original Blaschkoid distribution, with no extracutaneous involvement and only mild recurrences. This clinical course strongly supports the diagnosis of isolated linear psoriasis (type 1 mosaicism). Few pediatric cases in the literature have documented such a long and stable evolution, making this report a valuable contribution to the distinction between LP and ILVEN. The case highlights the importance of integrating clinical, histological, and longitudinal data when evaluating linear dermatoses in children.

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来源期刊
Dermatology Reports
Dermatology Reports DERMATOLOGY-
CiteScore
1.40
自引率
0.00%
发文量
74
审稿时长
10 weeks
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