Dental Research Journal最新文献

{"title":"Effect of 4-META on microtensile bond strength of cements to ceramics","authors":"Maliheh Nafisifard, H. Alaghehmand, Laleh Soleimani, Faraneh Mokhtarpour","doi":"10.4103/drj.drj_764_22","DOIUrl":"https://doi.org/10.4103/drj.drj_764_22","url":null,"abstract":"Background: This study assessed the effect of different concentrations of 4-methacryloyloxyethy trimellitate anhydride (4-META) added to silane on microtensile bond strength (µTBS) of light-cure and dual-cure resin cement to hybrid and zirconia-reinforced lithium silicate ceramics. Materials and Methods: This in vitro, experimental study was conducted on 32 Celtra Duo and 32 VITA Enamic ceramics bonded to Allcem Veneer light-cure and Allcem dual-cure resin cements using silane impregnated with 4-META in 0%, 2.5%, 5%, and 10 wt% concentrations in 16 groups (n = 4). The µTBS of specimens was measured by a universal testing machine and analyzed by the Kruskal–Wallis and Mann–Whitney tests, and the mode of failure was determined under a stereomicroscope and analyzed by the Chi-square test (alpha = 0.05). Results: The lowest mean µTBS was recorded in the Enamic ceramic group with 4-META (0%) bonded to dual-cure cement (14.26 MPa), and the highest mean µTBS was recorded in Enamic ceramic with 4-META (10%) bonded to light-cure cement (18.59 MPa) (P < 0.001). The µTBS of Celtra Duo was significantly higher than that of Enamic in bonding to light-cure cement using 4-META (2.5%) (P = 0.003). All failures (100%) were adhesive in most groups. The frequency of adhesive failure was the lowest (90%) in Celtra Duo bonded to dual-cure cement with 4-META (5%). Conclusion: According to the results of this pilot study, the addition of 4-META (10%) to silane caused a significant improvement in µTBS to light-cure cement. The addition of 4-META in all concentrations significantly improved the µTBS to Enamic ceramic in the use of dual-cure cement; however, it had no significant effect on µTBS of Celtra Duo. Nonetheless, the results should be interpreted with caution due to the relatively small sample size.","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"439 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140466205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-cancer effects of green synthesized gold nanoparticles using leaf extract of Annona muricata. L against squamous cell carcinoma cell line 15 through apoptotic pathway","authors":"S. Jeslin, Veeran Veeravarmal, Prasanth Thankappan, Paramasivam Arumugam, Percy Ida Augustine, R. Franklin, Dr. S. Jeslin Mary","doi":"10.4103/drj.drj_521_23","DOIUrl":"https://doi.org/10.4103/drj.drj_521_23","url":null,"abstract":"Background: Oral cancer remains one of the most dreadful diseases in developing nations. Currently, there has been a rise in the prevalence of tongue squamous cell carcinoma (SCC), with a poor prognosis. The use of standard treatment approaches against oral cancer patients brings about several side effects. In recent years, nanomedicine has provided a versatile platform for developing new targeted therapeutic modalities. However, safety remains a concern in the synthesis of nanoparticles (NPs). Therefore, the present study aims to synthesize safer phytoconstituent-mediated gold NPs (AuNPs) utilizing leaf extracts of Annona muricata, where the biochemical components of the plant leaf act as the reducing and capping agents in the synthesis of NPs, and to evaluate its anti-cancer activity against SCC. Materials and Methods: In this in vitro experimental study, AuNPs were synthesized through an effective, simple, and ecologically sound green synthesis method. After characterization of these synthesized AuNPs, in vitro assays such as 3-(4, 5-dimethylthiazole2-yl)-2, 5-biphenyl tetrazolium bromide, wound healing, and clonogenic assays were carried out to investigate the anti-cancer potential of green synthesized AuNPs in the human tongue SCC cell line (SCC-15), and the possible mechanism of action was evaluated through gene and protein expression analysis of Bax, Bcl-2, and p53 genes. The results were expressed as mean ± standard deviation using Statistical Package for Social Sciences (SPSS) 20.0 software and Student's t-test was performed for experimental data. P ≤0.05 were considered statistically significant. Results: The in vitro assays demonstrated that the synthesized AuNPs are exhibiting anti-cancer activity by apoptosis of SCC-15 cells in a dose-dependent manner. Further, it also revealed a highly significant decrease in anti-apoptotic Bcl-2 gene expression, whereas pro-apoptotic genes p53 and Bax revealed a highly significant increase, which is statistically significant compared to the control (P < 0.05). Conclusion: Our findings demonstrated that the AuNPs synthesized from A. muricata leaf extract could act as a novel anticancer agent, particularly against SCC, after further scrutiny.","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"488 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140466031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of polishing versus glazing of CAD-CAM ceramics on wear and surface roughness of opposing composite resin","authors":"Mina Sadat Khoramian Esfahani, Ghazaleh Ahmadi, B. Esmaeili","doi":"10.4103/drj.drj_757_22","DOIUrl":"https://doi.org/10.4103/drj.drj_757_22","url":null,"abstract":"Background: This study aimed to assess the effect of polishing versus glazing of computer-aided design-computer-aided manufacturing (CAD-CAM) ceramics on depth of wear and surface roughness of opposing composite resin. Materials and Methods: This in vitro study was conducted on 40 Z250 composite and 40 CAD-CAM ceramic specimens including Celtra Duo, Vita Mark II, e.max CAD, and Vita Suprinity ceramics. All ceramic specimens were roughened by a fine-grit bur after primary glazing to simulate an adjusted surface in the clinical setting. They were then randomly assigned to two subgroups and underwent reglazing or polishing. All composite and ceramic specimens underwent profilometry after surface treatment and prior to the wear test, and the results were recorded quantitatively. Composite specimens were then subjected to 120,000 wear cycles against ceramic specimens in a chewing simulator, and the depth of wear was measured by a scanner. Data were statistically analyzed by repeated measures two-way analysis of variance (ANOVA) and one-way ANOVA (α = 0.05). Results: Comparison of the surface roughness of composite specimens before and after the wear test revealed significant differences in both glazed Suprinity (P = 0.048) and Vita Mark II (P = 0.026) ceramics groups. The change in surface roughness after the wear test (compared with baseline) was significant in glazed (P = 0.000) and polished (P = 0.013) Vita Mark II and polished Suprinity (P = 0.037) ceramics, but this change was not significant in other ceramics (P > 0.05). The depth of wear after the wear test was not significantly different among the ceramic and composite subgroups (P > 0.05). Conclusion: Assessment of depth of wear and surface roughness of composite specimens showed that the polishing kits of CAD-CAM ceramics can serve as a suitable alternative to reglazing.","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"509 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140466093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of intelligent development (IQ & EQ) of children with cleft lip and palate","authors":"Rasool Esmaeili Maryan, M. Feizbakhsh, Zohreh Esmaeilian, Golnoosh Sedaghati","doi":"10.4103/drj.drj_58_23","DOIUrl":"https://doi.org/10.4103/drj.drj_58_23","url":null,"abstract":"Background: Attention to the issue of intelligence and its promotion in children with cleft lip and cleft palate (CL and CP) is necessary to reduce their injuries in life. This study aimed to determine the intelligence quotient (IQ) and emotional intelligence (EQ) in children with CL and CP in comparison to healthy children. Materials and Methods: In this descriptive study, 140 children, including 70 children with CL and CP, were selected from the Children treated in Craniofacial and Cleft Research Center, Spearman correlation, ANOVA and 70 healthy children were selected from the Pediatric Dentistry Department of Isfahan University, in the age range of 5–9 years. After obtaining the consent of the children's parents, the Raven IQ questionnaire and the Mayer and Salovey EQ questionnaire were given to the children. Data were analyzed by the Pearson correlation coefficient tests (α =0.05). Results: EQ score in healthy children was significantly higher than in children with CL and CP (P < 0.001). The percentage of IQ cognitive intelligence in healthy children and children with CL and CP was not significantly different (P = 0.641). In healthy children, no significant relationship was observed between cognitive intelligence IQ and EQ (r = 0.018, P = 0.882). However, among children with CL and CP, there was a significant inverse relationship between cognitive intelligence IQ and EQ (P < 0.001, r = −0.526). Conclusion: CL and CP have no effect on IQ in children, but it does affect EQ.","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"418 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140464951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphometric parameters of dental pulp in immature teeth in a sheep model after mechanical pulp exposure and restoration with reinforced zinc oxide-eugenol","authors":"Eshaghali Saberi, Z. Heidari, H. Mahmoudzadeh-Sagheb, Mahdieh Narouei, Lida Jafari, Alireza Mahmoudzadeh-Sagheb, Mahmoud Saadatian","doi":"10.4103/drj.drj_682_22","DOIUrl":"https://doi.org/10.4103/drj.drj_682_22","url":null,"abstract":"Background: The aim of the study was to investigate the morphometric parameters of dental pulp in open apices immature teeth in a sheep model after mechanical pulp exposure and restoration with reinforced zinc oxide-eugenol. Materials and Methods: In this experimental study, a total of 12 immature mandibular central incisors from six adult male sheep, weighing 30–40 kg and with the age of 1 year old with Merino race were examined. After anesthesia, the pulps of the teeth in the case group were mechanically exposed and then were restored with reinforced zinc oxide-eugenol and amalgam. In the control group, the teeth remained intact. The animals were sacrificed at intervals of 2, 4, 6, and 8 weeks (E2, E4, E6, and E8) in the case and 2 and 8 weeks (C2 and C8) in the control groups. Then, their teeth were removed with the surrounding supporting tissues and alveolar bones. Tissue processing and staining were done, and the sections were examined under a light microscope. The Kruskal–Wallis and Mann–Whitney U tests were used to analyze the data and compare the changes between the two groups. P < 0.05 was considered statistically significant. Results: In response to mechanical exposure, reparative or tertiary dentin was formed, and its thickness increased during the time of the study. The thickness of the odontoblastic layer in the E4 group was the highest amount. The pulp chamber diameter in the C2 group was significantly larger than the other groups, and the diameter of the apical foramen in the E8 was decreased significantly compared to the controls (P < 0.05). Conclusion: In response to mechanical exposure and restoration with reinforced zinc oxide-eugenol, some morphometric parameters of the dental pulp changed significantly in the sheep model compared to the controls.","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"108 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140469776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of surface energy and surface stability and adherence of <i>Candida albicans</i> to octa fluoro pentyl (meth) acrylate-coated PEEK using plasma spray.","authors":"Majid Jahangir, Alireza Hadi, Zahra Yadegari, Razieh Shahbazi, Parisa Amdjadi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Polyetheretherketone (PEEK) has favorable properties that make it able to be used as a denture base material, but it is also susceptible to the adhesion of microorganisms. In this study, we applied Octafluoropentyl (meth) acrylate (OFPA) coating on the PEEK polymer surface by using plasma spray and investigated the functional groups present on the surface, changes in the surface energy and <i>Candida albicans</i> adhesion.</p><p><strong>Materials and methods: </strong>In this experimental study, the samples were placed in a control group without surface preparation and three experimental groups that were subjected to plasma spray for 10, 30, and 60 s and then impregnated with degassed Octa fluoropentyl (meth) acrylate (Sigma-Aldrich, USA) monomer. Fourier transform infrared spectroscopy (FTIR) was used to identify the functional groups and new chemical bonds between PEEK and OFPA, and Sessile Drop Method was used to evaluate the surface's wettability. The surface morphology was checked using a LEXT OLS4000 (Olympus^®-Japan) microscope, and the inhibition of <i>C. albicans</i> adhesion was also checked by counting the colonies in terms of colony forming unit/mL (CFU/mL). Kurskal-Wallis analysis was conducted to assess <i>Candida</i> adhesion, while wettability was evaluated using analysis of variance and <i>post hoc</i> analyses. The level of statistical significance was set at <i>P</i> < 0.05.</p><p><strong>Results: </strong>FTIR analysis confirmed that a chemical between OFPA and PEEK was established. The samples showed a significant increase in the contact angle after 30 s of plasma application (CA = 88.2 ± 7.3). The contact angle decreased again by increasing the surface modification to 60 s (CA = 64.33 ± 5.5). Examining the surface morphology of the samples shows an increase in surface roughness with increasing plasma time up to 60 s. The number of adherent colonies was the lowest in 30 s group, but it was not statistically significant (<i>P</i> = 0.658).</p><p><strong>Conclusion: </strong>No statistically significant difference in <i>C. albicans</i> CFU/mL count was found between groups. The contact angle of the 30 s group was significantly higher than the control group.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10899159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139995839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the accuracy of apex locator, digital radiography, and cone-beam computed tomography in root canal working length determination in teeth with external root resorption: An <i>in vitro</i> study.","authors":"Seyed Mohsen Hasheminia, Sanaz Jahadi, Farida Ghazanfari Moghaddam, Shervin Bagherieh","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to compare the accuracy of apex locator, digital periapical radiography, and cone-beam computed tomography (CBCT) for determining the root canal working length (WL) in teeth with external root resorption (ERR).</p><p><strong>Materials and methods: </strong>In this <i>in vitro</i> study, the sample consisted of 54 extracted permanent single-rooted human teeth. ERRs were performed at the 3 mm apical root using 65% of nitric acid for 24 h. After determining the actual WL by K-file #10 (gold standard) with the visualization method, the teeth were mounted in alginate and the WL of each tooth was determined using the electronic apex locator (EAL) equipped with a K-file #15. The teeth were mounted with wax in the teeth sockets of a dry human mandible, and the images were obtained by digital phosphor plate receptors and CBCT scans. The mean registered WL of each method was statistically compared with the gold standard WL using one-way ANOVA with <i>P</i> < 0.001.</p><p><strong>Results: </strong>The mean ± standard deviation (SD) of actual WL was 16.00 ± 2.24. The mean ± SD of WLs determined by CBCT, EAL, and digital radiography were 15.38 ± 2.19, 15.52 ± 2.32, and 16.83 ± 2.20, respectively. This study showed that the mean measured WL with ERR in all methods was significantly different from the actual WL (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>This study showed that there was a significant difference between the actual mean WL and the EAL, digital periapical radiography, and CBCT mean WL. Thus, the combination of EAL and CBCT could be a reliable method for determining WL in the presence of ERR.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10899164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139995837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of the combination of myofunctional therapy (lip exercises) and activator high-pull headgear in the closure of interlabial gap in long-face skeletal class II patients with lip incompetence: A 6-8-month longitudinal randomized clinical trial.","authors":"Atyie Safar Alizade, Elmira Asadi, Alireza Jafari-Naeimi, Salmeh Kalbassi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Lip incompetence is an important issue in orthodontics. No study has evaluated the effects of the combination of headgear + lip exercises on lip incompetence. Therefore, this study was conducted.</p><p><strong>Materials and methods: </strong>This was a longitudinal randomized clinical trial on 29 subjects (16 controls and 13 experimental subjects). Both groups were treated with standardized activator high-pull headgear (and followed up monthly) for 6-8 months. In the experimental group, patients were also instructed to practice certain lip exercises 3 sessions a day, 5 times per session. Pre-/post-treatment interlabial gap, upper lip length and vermilion height, lower lip length and vermilion height, nasolabial angle, and profile convexity angle were measured clinically and photographically, immediately before treatment and after it. Data were analyzed using paired/unpaired <i>t</i>-tests (α = 0.025) and partial correlation coefficient controlling for the intervention type (α = 0.05).</p><p><strong>Results: </strong>Lip exercise plus activator headgear significantly changed/improved all parameters (<i>P</i> ≤ 0.006) over the 6-8-month course of treatment. Activator headgear alone changed/improved only 4 parameters: interlabial gap, upper and lower lip lengths, the lower lip vermilion height, and profile convexity (<i>P</i> ≤ 0.008). Compared to the control (activator headgear alone), in the experimental group, the changes observed in the interlabial gap closure (<i>P</i> = 0.011), upper lip lengthening (<i>P</i> = 0.002), and upper lip vermilion lengthening (<i>P</i> = 0.017) were significantly greater. Convexity angle corrections were more successful in cooperative patients (R = 0.469, <i>P</i> = 0.012). Cases with smaller pretreatment nasolabial angles may experience more changes in this angle after treatment (R = 0.581, <i>P</i> = 0.001).</p><p><strong>Conclusion: </strong>The addition of lip exercises to activator high-pull headgear can boost activator headgear's efficacy in treating lip incompetence.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"3"},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10899158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139995838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of middle mesial root canal in mandibular molars in an Iranian population: A micro-computed tomography study.","authors":"Alireza Farhad, Mohsen Hasheminia, Ehsan Hekmatian, Vahid Mojiri","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Knowledge about the anatomic variations of the root canal system and their prevalence is necessary for clinicians to ideally clean the root canal system. The anatomic complexity of the root canal system is one of the reasons for its inadequate debridement, resulting in residual microorganisms and root canal treatment failure. The present study aimed to evaluate the prevalence of middle mesial root canals in mandibular molars in an Iranian population.</p><p><strong>Materials and methods: </strong>The samples in the present descriptive/cross-sectional study consisted of mandibular first and second molars (<i>n</i> = 100, with 50 first and 50 s molars). A convenient sampling method was used to collect samples. The teeth were mounted in gypsum and scanned using a micro-computed tomography unit. The images were reconstructed with software, and the relevant checklist was completed by the observers. The data were analyzed with SPSS v26 using the Chi-squared test at a significance level of <i>P</i> < 0.05.</p><p><strong>Results: </strong>The prevalence of the middle mesial root canal in the present study was 36% for mandibular first molars and 22% for mandibular second molars, with an overall prevalence of 29%. The prevalence of the middle mesial root canal was not significantly different between the first and second mandibular molars (<i>P</i> = 0.12). The mean distance between the mesiobuccal and mesiolingual root canal orifices in the teeth with a middle mesial root canal was significantly higher than in those without the middle mesial root canal (<i>P</i> < 0.001). In addition, there was no significant difference in the prevalence of the middle mesial root canal between the teeth with and without the second distal root canal (<i>P</i> = 0.89).</p><p><strong>Conclusion: </strong>The prevalence of the middle mesial root canal in the studied population was 29%, which is significant clinically. In addition, the mean distance between the mesiobuccal and mesiolingual root canal orifices in teeth with a middle mesial root canal was higher than that in teeth without this root canal.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"9"},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10899162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139995888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of photobiomodulation on postoperative endodontic pain: A systematic review of clinical trials.","authors":"Seyyed Amir Seyyedi, Maryam Baghizadeh Fini, Reza Fekrazad, Selda Abbasian, Amir Ardalan Abdollahi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>This review aims to perform a complete evaluation of the impact of photobiomodulation (PMB) on postoperative endodontic pain.</p><p><strong>Materials and methods: </strong>The PRISMA checklist was used to perform this systematic review. The electronic databases were searched, including Google Scholar, PubMed, and Embase. Sixty-three papers were obtained through a main electronic search and a hand search. Nine trials met the criteria after screening the titles, abstracts, and/or full texts.</p><p><strong>Results: </strong>Seven out of nine studies showed that PMB has a significant impact on relieving postoperative endodontic pain, with no statistically significant difference in the severity of pain between the laser and control groups in the two remaining studies. In addition, eight studies showed no adverse effects, indicating that we can remove the adverse effects of drugs such as nonsteroidal anti-inflammatory drugs. However, one study showed evidence of the consequences of PMB application on teeth with symptomatic irreversible pulpitis. Therefore, it can be concluded that PMB should not be used in teeth with pain because of irreversible pulpitis.</p><p><strong>Conclusion: </strong>Although there is some understanding from a cellular viewpoint of the effects of PMB, there is still some uncertainty about whether these cell-level modifications impact reducing the postendodontic pain.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10899165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}