Dental Research Journal最新文献

{"title":"CD44 and EPCAM expression in pleomorphic adenoma and mucoepidermoid carcinoma: An immunohistochemical method.","authors":"Laleh Maleki, Bahareh Fattahi, Seyed Mohammad Razavi, Mina Shekarian, Shahnaz Eskandari","doi":"10.4103/drj.drj_545_24","DOIUrl":"https://doi.org/10.4103/drj.drj_545_24","url":null,"abstract":"<p><strong>Background: </strong>Recent studies have indicated that assessing the expression levels of cancer stem cell markers is critical in predicting the behavior of these neoplasms. This study aimed to evaluate and compare the expression levels of CD44 and epithelial cell adhesion molecule (EpCAM) markers in pleomorphic adenoma (PA) and mucoepidermoid carcinoma (MEC) using immunohistochemistry.</p><p><strong>Materials and methods: </strong>In this cross-sectional descriptive-analytical study, 20 samples each of PA and MEC were selected from Kashani Hospital, Isfahan, Iran, based on inclusion and exclusion criteria. Specimens were prepared using immunohistochemical methods and analyzed under an optical microscope. Pathologists evaluated microscopic grade, staining intensity and percentage, and the staining intensity distribution (SID) index. Statistical analysis was conducted with SPSS (version 26), employing the Kolmogorov-Smirnov test, <i>t</i>-test, Chi-square, and Fisher's exact test.</p><p><strong>Results: </strong>The mean frequency of stained cells for both CD44 (<i>P</i> = 0.39) and EpCAM (<i>P</i> = 0.40) markers showed no statistically significant differences between the PA and MEC groups. Similarly, the mean intensity of staining did not differ significantly for either CD44 (<i>P</i> = 0.40) or EpCAM (<i>P</i> = 0.18). The average SID index for the EpCAM marker in the MEC group was significantly higher than the PA group (<i>P</i> = 0.03) and for the EpCAM marker, there was a significant difference between the average SID index and all three variables of microscopic grade (<i>P</i> = 0.01), clinical stage (<i>P</i> = 0.00), and 3-year prognosis (<i>P</i> = 0.02).</p><p><strong>Conclusion: </strong>The use of EpCAM immunohistochemical marker may help to predict the behavior of salivary gland tumors and obtain better treatment measures for patients.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"16"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shear bond strength evaluation of new computer-aided design - computer-aided manufacturing chromium-cobalt alloy (Sintron) with two different types of cement: An in vitro study.","authors":"Mohammad Mahdi Khanmohammadi, Ezatollah Jalalian, Azita Mazaheri Tehrani, Nozhan Azimi, Arash Zarbakhsh","doi":"10.4103/drj.drj_238_24","DOIUrl":"https://doi.org/10.4103/drj.drj_238_24","url":null,"abstract":"<p><strong>Background: </strong>Any deficiency or problem in the shear bond strength between restoration and tooth surface can lead to recurrent decay, gingival issues, and associated esthetic concerns. Cement acts as a material to bond restorations to the tooth surface, filling the void space between the tooth and the restoration to establish this bond. This study aims to investigate the bonding strength of two common types of cement - polycarboxylate and zinc phosphate - with Sintron alloy (chromium-cobalt) in dental restorations.</p><p><strong>Materials and methods: </strong>This research is conducted <i>in vitro</i> on 24 Sintron alloy discs cemented with two types of polycarboxylate (Poly-F, Dentsply, US) and zinc phosphate cement (Harvard Cement, Germany) on 24 extracted maxillary central incisors. Teeth were sandblasted with 50-micrometer aluminum oxide (Al₂O₃) particles. Disc-shaped alloy specimens with specific dimensions were prepared. The specimens were then bonded to the teeth surface using each cement and were subjected to shear bond strength testing using a Universal Testing Machine (Instron, 3367, Canton, MA, USA). An independent sample <i>t</i>-test was performed with <i>P</i> value significance of lower than 0.05.</p><p><strong>Results: </strong>The <i>t</i>-test with <i>P</i> = 0.150 showed no significant difference between the zinc phosphate and polycarboxylate cement groups.</p><p><strong>Conclusion: </strong>The study found no statistically significant difference in the bond strength of Sintron alloy when using zinc phosphate and polycarboxylate cement. Therefore, it can be concluded that the bond strength is similar for both cements.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"13"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and radiological outcomes of osseodensification and crestal approach sinus kit for transcrestal sinus elevation - A randomized clinical trial.","authors":"Sathyavalli Veluri, Sruthima N V S Gottumukkala, Satyanarayana Raju Mantena, Gautami S Penmetsa, Ksv Ramesh, Mohan Kumar Pasupuleti, Dinesh Gera","doi":"10.4103/drj.drj_711_23","DOIUrl":"https://doi.org/10.4103/drj.drj_711_23","url":null,"abstract":"<p><strong>Background: </strong>The aim of the present study was to evaluate the clinical and radiological effectiveness of transcrestal sinus elevation and simultaneous implant placement using osseodensification (OD) and crestal approach sinus (CAS) instruments.</p><p><strong>Materials and methods: </strong>This randomized controlled double-blinded clinical trial included 20 participants with edentulous spaces requiring 20 implants having residual bone height >5 mm in the posterior maxilla. Participants were randomly allocated into the CAS group and OD group. Indirect sinus elevation with simultaneous implant placement was performed in both groups. Implant stability (IS) was evaluated at baseline and 3 months. Crestal bone loss (CBL) was measured at 3, 6, and 12 months. Apical bone gain (ABG) was measured at 6 and 12 months. Surgical time and patient comfort using the Visual Analog Scale were assessed during the surgery. Unpaired <i>t</i>-test, ANOVA, and Friedman tests were used for inter- and intragroup comparisons. <i>P</i> ≤ 0.05 was deemed statistically significant.</p><p><strong>Results: </strong>Sinus elevation and simultaneous implant placement showed good clinical and radiological outcomes in both groups. Intergroup comparison showed a significantly greater primary and secondary IS (<i>P</i> = 0.005, 0.008) in the OD group. CBL was less in the OD group (<i>P</i> = 0.02 and 0.03 on mesial and distal sides) than in the CAS group at 6 months of evaluation. ABG was higher in the OD group (4.164 ± 0.293) than the CAS group (2.819 ± 0.415). The average surgical time taken was greater (87.00 ± 15.49 min) in the CAS group than in the OD group (69.00 ± 20.24 min).</p><p><strong>Conclusion: </strong>Both CAS and OD groups showed significant improvement in all parameters. OD group showed greater benefits in terms of enhanced primary stability, less CBL, enhanced ABG, and lesser surgical time compared to the CAS group.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"17"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical composition, antibacterial, and antifungal effects of <i>Citrus medica</i> (citron), <i>Pimpinella anisum</i> (anise), and <i>Artemisia dracunculus</i> (tarragon) on oral pathogens: An <i>in vitro</i> study.","authors":"Sina Mohammadzadeh, Zahra Rezazadeh, Parisa Jafari, Fakhri Haghi Tomatari, Samineh Jafari, Mina Mohebian","doi":"10.4103/drj.drj_390_24","DOIUrl":"https://doi.org/10.4103/drj.drj_390_24","url":null,"abstract":"<p><strong>Background: </strong>Dental caries are caused by acidic by-products from bacterial fermentation of dietary carbohydrates and can lead to oral complications. Oral candidiasis is another disease affecting quality of life, especially in diabetic and immunocompromised patients. Interest in using Persian medicine to manage oral diseases has been growing recently. Persian medicine texts highlight medicinal plants such as <i>Artemisia dracunculus</i>, <i>Citrus medica</i>, and <i>Pimpinella anisum</i> for oral health benefits. The present research explores the antimicrobial effects of these plants against microorganisms causing caries and oral candidiasis.</p><p><strong>Materials and methods: </strong>This is an <i>in vitro</i> study, aimed to evaluate the chemical composition, and antimicrobial effects of <i>C. medica</i>, <i>P. anisum</i>, and <i>A. dracunculus</i> on oral pathogens. Based on criteria such as accessibility, recognizability, and novelty, leaves of <i>A. dracunculus</i>, peels of C<i>. medica</i>, and seeds of <i>P. anisum</i> were chosen. Their chemical compositions were analyzed after procuring the plant samples and preparing their essential oils (EOs). Subsequently, the diameters of the inhibition zones and their minimum inhibitory concentration (MIC) and minimum bactericidal concentration/minimum fungicidal concentration values were measured.</p><p><strong>Results: </strong>The major chemical components of <i>P. anisum</i>'s EO (PAEO), <i>A. dracunculus'</i> EO (ADEO), and <i>C. medica</i>'s EO (CMEO) were estragole (75.77%), anethole (89.03%), and limonene (92.31%), respectively. All pathogens were susceptible to all EOs except <i>Streptococcus salivarius</i>, which was resistant to CMEO and had the highest MIC. Except for this EO, all the other EOs showed inhibition zones with diameters ranging from 6 to 30 mm, ADEO being the most effective. In MICs, <i>Lactobacillus acidophilus</i> was the most sensitive microorganism tested with MIC. In contrast, the most resistant microorganism was <i>S. salivarius</i>.</p><p><strong>Conclusion: </strong>The attained results demonstrated that the examined plants possess notable antimicrobial properties against oral pathogens.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"15"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the accuracy of 3D-printed casts versus plaster casts for tooth-supported and implant-supported restorations.","authors":"Hedie Derakhshi, Mohammad Alihemmati, Seyed Mohammad Reza Hakimaneh, Mohammad Amin Bafandeh, Maryam Jahangiri, Sayed Shojaedin Shayegh","doi":"10.4103/drj.drj_382_24","DOIUrl":"https://doi.org/10.4103/drj.drj_382_24","url":null,"abstract":"<p><strong>Background: </strong>The use of 3D printers in dentistry is expected to increase in the future. However, there is limited information available on the accuracy of dental 3D printers for creating dental and implant models. This study aimed to compare the accuracy of 3D-printed casts and traditional plaster casts for the fabrication of tooth-supported and implant-supported restorations.</p><p><strong>Materials and methods: </strong>This <i>in vitro</i> study involved a dental model with implant analogs placed at the sites of the right first premolar and molar for an implant-supported bridge and the left first premolar and molar that received preparation for a tooth-supported bridge. Addition silicone impressions were made and poured with dental stone to create 10 plaster casts. The model was scanned using an intraoral scanner, and 20 casts were 3D-printed using digital light processing (DLP) and liquid crystal display (LCD) printers (10 casts for each method). All 30 casts, including the reference model, were scanned using a laboratory scanner, and the obtained Standard Triangle Language files were superimposed in Geomagic software. Data analysis revealed violations of normality and homogeneity of variances. As a result, the Kruskal-Wallis <i>H</i> test, a nonparametric method, was employed to compare root mean square (1 RMS = 100 μm) values across three groups. All statistical analyses were performed using SPSS version 27. RMS values were calculated (<i>P</i> < 0.05).</p><p><strong>Results: </strong>The RMS value was significantly lower in the conventional plaster cast group compared to the LCD group (<i>P</i> = 0.002). However, there was no significant difference between the LCD and DLP groups (<i>P</i> = 0.214) or between the conventional and DLP groups (<i>P</i> = 0.345). The interdental distance in the conventional group was significantly lower than that in the 3D-printed groups (<i>P</i> < 0.05), but there was no significant difference between the two printing methods (<i>P</i> = 0.31). The interimplant distance was lower in the 3D-printed groups compared to the conventional group, and this difference was significant between the DLP and conventional groups (<i>P</i> = 0.02).</p><p><strong>Conclusion: </strong>Although plaster casts demonstrated higher accuracy, 3D-printed casts using additive technology yielded accurate results within the clinically acceptable range (<200 μm).</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"14"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative analysis of patient satisfaction with various methods of digital smile design and simulation.","authors":"Mahsa Babaei, Mehrdad Kazemian, Mehrdad Barekatain","doi":"10.4103/drj.drj_254_24","DOIUrl":"10.4103/drj.drj_254_24","url":null,"abstract":"<p><strong>Background: </strong>Digital smile design (DSD) is a technique that utilizes the scientific methods and advanced software to design patients' smiles, presenting the visualized smile map directly to the patient. However, patients may not always find the proposed smile satisfactory or feel a sense of alignment with it. To address this concern, dentists have been integrating the tooth shape with the overall facial shape and other parameters to develop a personalized smile plan for each patient.</p><p><strong>Materials and methods: </strong>This study employed a descriptive-analytical, cross-sectional research design conducted during the summer and fall of 2022. This research sought to evaluate patient satisfaction levels associated with three distinct DSD techniques: Visagism, Proportional, and Stepwise Comprehensive. A sample of 20 participants, evenly split between males and females, was selected, all of whom were seeking smile design treatment and did not present with skeletal, jaw, facial, or periodontal complications. Interviews were conducted to analyze personality and temperament, and smile maps were created utilizing the Visagism, Stepwise Comprehensive, and Proportional methods. Subsequently, patients evaluated the designs produced by all three methods and completed a satisfaction questionnaire. Nonparametric statistical tests, namely the Kruskal-Wallis test and post hoc Bonferroni tests, were used to examine the research hypotheses at a significance level of 0.05.</p><p><strong>Results: </strong>The results indicated a high level of satisfaction with all three DSD methods, with no statistically significant differences observed among them. These results suggest that all three approaches effectively met the patients' expectations and preferences.</p><p><strong>Conclusion: </strong>The outcomes of this study have practical implications for dental professionals engaged in DSD, potentially enhancing patient experiences and treatment outcomes. Further research in this domain may explore the additional factors that could influence patient satisfaction and refine the DSD process.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"10"},"PeriodicalIF":0.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of the gap between the cast post and residual gutta-percha and cement type on microleakage of endodontically treated teeth using the fluid filtration method.","authors":"Ramin Mosharraf, Saeid Farahmand, Sarah Arzani, Hamidreza Hemati, Majid Abolhasani, Behnam Golshirazi, Sharare Jahangiri","doi":"10.4103/drj.drj_418_24","DOIUrl":"10.4103/drj.drj_418_24","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to investigate the impact of the distance between the gutta-percha and the post, as well as the type of cement used, on the incidence of microleakage in endodontically treated teeth.</p><p><strong>Materials and methods: </strong>This experimental-laboratory study involved 72 single-canal, single-rooted teeth, which were randomly sorted into six study groups and two control groups, each containing nine teeth. The six groups were further divided based on the distance between gutta-percha and post (0 mm, 0-2 mm, and >2 mm) and then categorized by cement type into glass ionomers and resins. Microleakage was evaluated using the fluid filtration method at 15 and 30 days. Data were analyzed using SPSS software, employing between-subjects effects and <i>post hoc</i> Tukey tests at a 5% significance level.</p><p><strong>Results: </strong>Cement type did not significantly affect microleakage (<i>P</i> = 0.598). However, microleakage increased significantly with larger gaps between the post and remaining gutta-percha (<i>P</i> = 0.002). No significant difference in microleakage was observed between the gapless and ≤2 mm groups (<i>P</i> = 0.328). Similarly, ≤2 mm and >2 mm groups did not show any notable difference (<i>P</i> = 0.054). However, the difference in microleakage between the gapless group and the ≥2 mm gap group was significant (<i>P</i> = 0.001).</p><p><strong>Conclusion: </strong>This study found no significant difference in microleakage between glass ionomers and resin cements. Only gaps >2 mm significantly affected microleakage.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"11"},"PeriodicalIF":0.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of short implants numbers and prosthesis design on stress in the posterior mandible: FE analysis.","authors":"Hamid Hosseini Naghavi, Reza Amid, Douglas Deporter, Mohammad Ketabi","doi":"10.4103/drj.drj_531_24","DOIUrl":"10.4103/drj.drj_531_24","url":null,"abstract":"<p><strong>Background: </strong>This study assessed the effect of the number of short implants on stress and strain distribution in bone in the posterior mandible using finite element analysis (FEA).</p><p><strong>Materials and methods: </strong>The study design utilized FEA, a computational technique. In FEA models, short implants (4 mm diameter and 6 mm length) were placed at the site of the mandibular first premolar to the second molar in four models: (I) two implants at the sites of teeth #4 and #7 with two pontics at the sites of teeth #5 and #6, (II) three implants at #4, #5, and #7 with one pontic at #6, (III) three implants at #4, #6, and #7 with one pontic at #5, and (IV) four implants at #4, #5, #6, and #7 with no pontic. A 100 N load was applied vertically and at a 30° angle to the occlusal surface of the crowns. Stress and strain distribution patterns in bone were evaluated using ANSYS Workbench.</p><p><strong>Results: </strong>The highest maximum von Mises and shear stress and strain values under vertical and off-axial loadings were observed in the model with two short implants at the sites of teeth #4 and #7 with two pontics at the sites of teeth #5 and #6. In general, the highest stress and strain values were recorded following the application of off-axial loads compared to vertical loads. In all models, the highest stress was noted in the cervical part of the implants, while the maximum strain occurred in the apical part of the implants.</p><p><strong>Conclusion: </strong>Increasing the number of short implants significantly reduces stress and strain values in peri-implant bone.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"12"},"PeriodicalIF":0.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>In vitro</i> comparison of antioxidant, cytotoxic, and antibacterial (against <i>Aggregatibacter actinomycetemcomitans</i>) effects of <i>Citrus reticulata</i>, <i>Olea europaea</i> extracts, and essential oils.","authors":"Surena Vahabi, Maryam Torshabi, Seyedeh Zahra Mirsharif","doi":"10.4103/drj.drj_110_24","DOIUrl":"10.4103/drj.drj_110_24","url":null,"abstract":"<p><strong>Background: </strong>This study compared the antioxidant, cytotoxic, and antibacterial effects of <i>Citrus reticulata (C. reticulata)</i> peel and <i>Olea europaea (O. europaea)</i> leaf hydroalcoholic extracts and essential oils.</p><p><strong>Materials and methods: </strong>In this <i>in vitro</i> study, the antibacterial effect of the <i>C. reticulata</i> and <i>O. europaea</i> extracts and essential oils was evaluated on <i>Aggregatibacter actinomycetemcomitans</i> (<i>A. actinomycetemcomitans</i>) by the agar diffusion test. Their minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined by the broth microdilution method. Their cytotoxicity against human gingival fibroblasts was evaluated by the methyl thiazolyl tetrazolium assay in 24 and 72 h, and their antioxidant effect was assessed by the 2,2-diphenyl-1-picrylhydrazyl assay. Data were analyzed by ANOVA and Tukey's test (<i>P</i> < 0.05).</p><p><strong>Results: </strong>The <i>O. europaea</i> hydroalcoholic extract and <i>C. reticulata</i> essential oils had significant antibacterial effects on <i>A. actinomycetemcomitans</i>. The highest and lowest growth inhibition zones belonged to <i>C. reticulata</i> essential oils (40.0 ± 0.0 mm) and <i>O. europaea</i> extract (32.3 ± 2.2 mm), respectively. The MIC and MBC were 0.78 v/v% for <i>O. europaea</i> extract and 6.25% for <i>C. reticulata</i> essential oils. Unlike the essential oils (1%, 5%, and 10% v/v), none of the extracts showed significant cytotoxicity at low concentrations (1% v/v). All essential oils and extracts, particularly <i>O. europaea</i> and <i>C. reticulata</i> extracts, had significant antioxidant effects.</p><p><strong>Conclusion: </strong>Of the tested materials, <i>O. europaea</i> extract had the highest potential for possible use as an organic mouthwash due to its strong antibacterial and antioxidant effects and absence of cytotoxicity in low concentrations.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"9"},"PeriodicalIF":0.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes of dental implants placed in the augmented maxillary sinus: A 5-year retrospective study.","authors":"Roohollah Naseri, Amin Ghadirian, Mohammadjavad Shirani","doi":"10.4103/drj.drj_96_24","DOIUrl":"https://doi.org/10.4103/drj.drj_96_24","url":null,"abstract":"<p><strong>Background: </strong>Factors influencing the success of an implant placed in augmented maxillary sinus need to be recognized. The aim of this study was to investigate the effect of various oral health conditions and treatment plan details on the clinical and radiographical outcomes of implants placed in the augmented sinus.</p><p><strong>Materials and methods: </strong>In this clinical retrospective study, 39 participants (81 implants) that received dental implants after sinus lifting between January 2005 and July 2016 were evaluated. All the participants were examined by an operator clinically and radiographically in a blinded manner. A checklist including oral health and host condition, implant and prosthesis characteristics, and surgical approach variables was completed for each participant. The effect of these variables on probing depth (PD), marginal bone loss, bone formation in sinus, and patient satisfaction was analyzed using analysis of covariance models. <i>P</i> <0.05 was considered statistically significant.</p><p><strong>Results: </strong>Survival rates after surgery and restoration placement were 93% and 100%, respectively. PD was found to be significantly higher in restorations with infragingival finish lines over 1.5 mm and in implants with score \"2\" for gingival index. Moreover, more bone formation was observed in implants with score \"0\" compared with score \"2\" for gingival index. In addition, the participants with plaque score \"0\" reported significantly more satisfaction than the participants with score \"2\" for plaque index.</p><p><strong>Conclusion: </strong>Inflamed gingiva was associated with more PD and less peri-implant bone formation in maxillary sinus. In addition, more patient satisfaction was reported by participants that had better plaque control.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}