Dental Research Journal最新文献

{"title":"The effect of sandblasting distances on the shear bond strength of a self-etch and total-etch adhesive system to cervical dentin in the gingival wall of Class II restorations.","authors":"Sima Gholami, Alireza Boruziniat, Hossein Bagheri, Reza Shakiba","doi":"10.4103/drj.drj_398_24","DOIUrl":"10.4103/drj.drj_398_24","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to examine the effect of sandblasting on the shear bond strength (SBS) of two adhesive systems on cervical dentin in the gingival wall of Class II restorations at two different distances.</p><p><strong>Materials and methods: </strong>In this <i>in vitro</i> study, 88 intact premolars were used. After creating a natural smear layer, samples were divided into self-etch (CLEARFIL LINER BOND F) and total-etch (Adper Single Bond 2) groups (<i>n</i> = 44). Each group was subdivided into subgroups (<i>n</i> = 22) for sandblasting at 5 mm or 10 mm, with the contralateral half as control. Following sandblasting (50-μm particles, 2 bar, 2 s), the resin composite was bonded to the dentin surface, with the SBS of the samples measured using a universal testing machine. The samples were examined using a scanning electron microscope (SEM) and analyzed by an energy dispersive X-Ray (EDX). The results were analyzed using three-way repeated measures analysis of variance and Chi-square tests (α = 0.05).</p><p><strong>Results: </strong>Sandblasting significantly reduced the SBS in both adhesive groups (<i>P</i> < 0.001). However, the adhesive system and distance did not significantly affect the bond strength (<i>P</i> > 0.05). The SEM images displayed the formation of irregularities in the smear layer, and EDX analysis revealed the presence of residual alumina particles on the blasted dentin samples.</p><p><strong>Conclusion: </strong>Cervical dentine sandblasting reduced the adhesive SBS regardless of the 5- or 10-mm distance or the adhesive system used. Thus, sandblasting is not recommended as a method of dentin preparation before restoring cervical lesions.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"30"},"PeriodicalIF":0.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334089/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain perception and sEMG of masticatory muscle in clear aligners vs. conventional orthodontics: A systematic review and meta-analysis.","authors":"Simran Neeraj Budhraja, Lalita Girish Nanjannawar, Jiwanasha Manish Agrawal, Shraddha Subhash Shetti, Sangamesh Gurunath Fulari, Harshal Santosh Patil","doi":"10.4103/drj.drj_367_24","DOIUrl":"10.4103/drj.drj_367_24","url":null,"abstract":"<p><strong>Background: </strong>Clear aligner therapy (CAT) has gained popularity as an alternative to Conventional Orthodontic Treatments (COT) for its potential to reduce pain and discomfort. This systematic review and meta-analysis aimed to compare pain perception and surface electromyography (sEMG) in masticatory muscles between CAT and COT groups.</p><p><strong>Materials and methods: </strong>A comprehensive search of multiple electronic databases was conducted to identify relevant studies. The PRISMA guidelines were employed to ensure transparency and completeness in reporting and was registered in PROSPERO (CRD42024556800).</p><p><strong>Results: </strong>Nine studies were considered for inclusion. The meta-analysis revealed a nonsignificant difference in Visual Analog Scale scores between CAT and COT groups, with a mean difference (MD) of -2.77 (95% confidence interval [CI]: -7.25, 1.71), <i>P</i> = 0.23. The heterogeneity test revealed significant heterogeneity among studies (<i>I</i>² = 100%). In contrast, the sEMG activity scores showed a nonsignificant difference between CAT and COT groups (MD = -0.80, <i>P</i> = 0.60). In addition, the odds ratio for patients requiring analgesics was 0.23 (95% CI: 0.08, 0.65), <i>P</i> = 0.005, suggesting a significant difference between CAT and COT groups.</p><p><strong>Conclusion: </strong>The results suggest that CAT may be associated with improved patient outcomes, including reduced pain and discomfort, as well as lower analgesic consumption. However, the evidence is not conclusive, and further research is needed to fully understand the differences between CAT and COT.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"29"},"PeriodicalIF":0.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Root development of immature necrotic permanent teeth following regenerative endodontic process: Case series.","authors":"Abbasali Khademi, Pedram Iranmanesh, Ali Akhavan, Movahed Ghassem Yeganeh, Samira Khalifezade Esfahani","doi":"10.4103/drj.drj_1_25","DOIUrl":"10.4103/drj.drj_1_25","url":null,"abstract":"<p><p>Regenerative endodontics is an expedient therapeutic strategy for necrotic teeth with open apex. The promising result of clinical research in the regenerative endodontic treatment field is published. The main goal of this case series is to present the radiographic and clinical findings of the regenerative endodontic procedure.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"28"},"PeriodicalIF":0.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>In vitro</i> comparison of color stability of resin-modified glass ionomer and Cention N bioactive restorative material.","authors":"Azadeh Khazaei Zadeh, Sahebeh Haghi, Mona Drikvand","doi":"10.4103/drj.drj_416_24","DOIUrl":"10.4103/drj.drj_416_24","url":null,"abstract":"<p><strong>Background: </strong>This study compared the color stability of resin-modified glass ionomer (RMGI) and Cention N bioactive restorative material following exposure to different coloring solutions.</p><p><strong>Materials and methods: </strong>In this <i>in vitro</i> experimental study, 12 specimens were fabricated from Cention N and Fuji II LC RMGI and immersed in Turkish coffee, Nescafe, cola, and distilled water as control (<i>n</i> = 3). The color parameters of the specimens were measured after 1, 7, and 28 days of immersion in the respective solutions, and their color change (ΔE) was calculated. Data were analyzed using repeated measures ANOVA Friedman test and two-way ANOVA (alpha = 0.05).</p><p><strong>Results: </strong>On day 1, the highest and lowest ΔE values were noted in Cention N specimens immersed in Nescafe and Cention N specimens immersed in cola, respectively. On days 7 and 28, the highest and lowest ΔE values were found in RMGI specimens immersed in Nescafe and Cention N specimens immersed in cola, respectively. The effects of the type of material and type of coloring solution and their interaction effect on ΔE of specimens at different time points were statistically significant (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Within the limitations of this <i>in vitro</i> study, the results showed that Fuji II LC RMGI had lower color stability than Cention N in the long term. Nescafe caused the greatest discoloration in Fuji II LC, while Turkish coffee caused the greatest discoloration in Cention N specimens.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"24"},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of herbal products with antifungal drugs in cure of oral candidiasis: A systematic review.","authors":"Faezeh Khozeimeh, Negar Ghadiri, Behzad Zolfaghari, Bahareh Tahani","doi":"10.4103/drj.drj_415_24","DOIUrl":"10.4103/drj.drj_415_24","url":null,"abstract":"<p><strong>Background: </strong>Oral candidiasis is one of the most common fungal infections affecting the oral mucosa. It is usually managed by taking antifungal medication that might result in side effects such as toxicity and drug resistance. Therefore, consumption of herbal medicine with antifungal activity and fewer side effects has become popular. This study is a systematic review to investigate the improvement and reduction of oral candidiasis symptoms by herbal compounds compared to conventional antifungal drugs.</p><p><strong>Materials and methods: </strong>PubMed, Scopus, Web of Science, Cochrane, and Magiran databases were searched from 1995 to 2021 based on the keywords of the question formula - oral candidiasis (P), herbal compounds (I), antifungal drugs (C), and improvement of clinical symptoms and laboratory tests (O) - to find related randomized controlled trials (RCTs) in English and Persian languages. Related articles were extracted based on inclusion and exclusion criteria and critically appraised using the modified-CONSORT checklist. The risk of bias was also assessed using the Cochrane tool.</p><p><strong>Results: </strong>After removing duplicates and checking the title and abstract of the articles, 98 articles from 1995 to November 2021 of 715 were reviewed. 83 RCTs were excluded due to non-relevancy and 15 remained for critical appraisal, of which 5 articles were rejected. Finally, 10 articles were included in the systematic review. Based on the risk of bias assessment, one article had low risk, 6 articles had unclear risk, and 3 articles had a high risk of bias. Herbal compounds were applied in the form of gel in 3 articles, in the form of ointment and mouthwash in 1 and 6 articles, respectively. In terms of clinical improvement and laboratory findings, herbal compound mouthwashes and ointment did not have a significant difference from conventional antifungal drugs, but the articles related to compound gels reported variable effects (better, similar, and weaker). Furthermore, herbal compounds generally had more patient satisfaction than antifungal drugs.</p><p><strong>Conclusion: </strong>It seems that herbal compounds have clinical applications in the treatment of oral candidiasis and gained more patients' satisfaction. To achieve more valid results, it is suggested to conduct more RCTs with a low risk of bias.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"23"},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influencing the accuracy of electronic apex locators: A scoping review.","authors":"Shayan Golkar, Abbasali Khademi, Amin Saatchi, Amir Ghorani, Pedram Iranmanesh","doi":"10.4103/drj.drj_634_23","DOIUrl":"10.4103/drj.drj_634_23","url":null,"abstract":"<p><strong>Background: </strong>The aim of this scoping review (ScR) according to the population, concept, and context question outline was: What factors can affect the accuracy of electronic apex locators (EALs) (concept) when determining the root canal terminus of human permanent teeth (population) in experimental studies (context)?</p><p><strong>Materials and methods: </strong>A ScR was performed and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews checklist using the following databases: PubMed/Medline, Scopus, Web of Science, and ProQuest. Studies that investigated the influence of a factor on the accuracy of the EALs were screened and included according to the inclusion criteria.</p><p><strong>Results: </strong>A total of 1761 records were retrieved, leading to 805 studies after duplicates were removed. Applying inclusion and exclusion criteria resulted in the inclusion of 166 studies. The 20 potential influencing factors include generation/electrical working mechanism, method for application of EALs, root canal curvature, root canal length, tooth type, maxillary sinus proximity, lateral foramen, major apical foramen diameter/file size, file alloy, apical patency, preflaring, apical periodontitis/resorption, internal root resorption, perforation, irrigants, solvents, and medicaments, pulp contents, pulp vitality, orthodontic brackets, endodontic retreatment, and electromagnetic interferences were detected.</p><p><strong>Conclusion: </strong>Although the accuracy of EALs is acceptable in most cases, the use of radiography along with EALs remains advisable to confirm the measurement in clinical scenarios.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"26"},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12252002/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of different methods of saliva decontamination on microshear bond strength of composite to composite: An <i>in vitro</i> study.","authors":"Sara Ordooei Javan, Reza Movahedian, Somayeh Hosseini Tabatabaei","doi":"10.4103/drj.drj_736_23","DOIUrl":"10.4103/drj.drj_736_23","url":null,"abstract":"<p><strong>Background: </strong>During the incremental technique of composite restorations, it is possible to be exposed to contamination of the oral environment. This study aimed to compare the effect of saliva contamination and different methods of saliva decontamination on microshear bond strength within composite surfaces.</p><p><strong>Materials and methods: </strong>This <i>in vitro</i> study created 24 rectangular XT composite blocks using a silicone mold (24 mm × 10 mm × 10 mm). The blocks were divided into eight groups as follows: Group 1: Control group (without contamination); Group 2: Contaminated with saliva; Group 3: saliva + dried; Group 4: saliva + rinsed + dried; Group 5: saliva + rinsed + dried + Clearfil Self Etch Bond; Group 6: saliva + 96% ethanol alcohol; Group 7: saliva + chlorhexidine + rinsed + dried; and Group 8: saliva + rinseddried + All-Bond Universal bond. Fifteen tubes (0.7 mm × 1 mm) were attached to the prepared surfaces in each group, with five tubes allocated to each block. They were filled with composite and light-cured and stored in distilled water for 24 h. They were tested under a microshear test. The data were analyzed using one-way analysis of variance (ANOVA) and Tukey's honest significant difference (HSD) test (<i>P</i> < 0.05).</p><p><strong>Results: </strong>One-way ANOVA test demonstrated significant differences among the groups concerning the mean bond strength (<i>P</i> < 0.001). Tukey's HSD test indicated that the bond strengths in groups 6 and 8 were similar to the control group, showing no significant difference. The lowest bond strength was observed in group 2, which measured 6 MPa.</p><p><strong>Conclusion: </strong>Decontamination with rinsed + dried + All-Bond Universal bond and 96% ethanol alcohol were the most effective methods for improving the contaminated composites' microshear bond strength.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"27"},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of airflow on enamel surface roughness and color change.","authors":"Azam Valian, Zahra Jaberi Ansari, Mohammadmoein Rezaei","doi":"10.4103/drj.drj_604_24","DOIUrl":"10.4103/drj.drj_604_24","url":null,"abstract":"<p><strong>Background: </strong>In dentistry, esthetic restorations are vital. Adequate polishing can minimize color changes of a tooth. The aim of this study was to evaluate the effect of the Prophy-Mate neo device, which uses airflow, on surface roughness and color changes in enamel.</p><p><strong>Materials and methods: </strong>In this <i>in-vitro</i> study included 30 teeth immersed in tea solution for 7 days. The specimens were divided into three groups based on the polishing procedure (airflow with calcium carbonate, airflow with sodium bicarbonate, and diamond paste). The whitening procedure was performed according to the instructions for each powder of airflow (Prophy-Mate neo, NSK, Japan) and paste. After polishing, the specimens were again immersed in a tea solution for another 7 days. Color assessment was carried out at baseline (T1) and after polishing (T2) using the CIELab* system. In addition, the morphology of the enamel surface for each specimen from each group was evaluated by profilometer at T1 and T2, and the paired <i>t</i>-test and Tukey's were used to compare results between groups.</p><p><strong>Results: </strong>The variation in surface roughness (Ra) between calcium carbonate (0.381 μm) and sodium bicarbonate (0.447 μm) powders was not significant, but the performance of diamond paste was significantly better. The difference between the secondary staining after polishing was lower than the pigment absorption in the primary staining (before polishing) in the diamond paste group.</p><p><strong>Conclusion: </strong>Overall, the study did not show any significant reduction in the amount of surface roughness and color changes in airflow compared to traditional polishing methods. The cost and services of the Prophy-Mate neo device make it challenging to introduce airflow as an alternative to conventional techniques (<i>P</i><0.05).</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"25"},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apical debris extrusion with Denco Gold and Blue rotary files: An <i>in vitro</i> study.","authors":"Ali Akhavan, Seyed Mohsen Hasheminia, Azadeh Kheradyar, Hanieh Haghpanah, Melika Sadat Araghbidi Kashani, Pedram Iranmanesh","doi":"10.4103/drj.drj_526_24","DOIUrl":"10.4103/drj.drj_526_24","url":null,"abstract":"<p><strong>Background: </strong>Minimizing apical debris extrusion may help reduce postoperative pain, flare-ups and enhance the patient's comfort. This study aimed to compare the apical debris extrusion weights of two rotary file systems, Denco Gold and Denco Blue, with those of hand files.</p><p><strong>Materials and methods: </strong>In this <i>in vitro</i> study, 69 mandibular first molars with a curvature < 10° and two separate root canals and foramen in the mesial root were selected. The samples were randomly divided into three groups: Denco Blue rotary file, Denco Gold rotary file, and hand files. After instrumentation, the extruded apical debris was gathered in glass containers and dehumidified. The weight of the debris was measured and compared. Data analysis was conducted using SPSS 22 with one-way analysis of variance and Tukey tests.</p><p><strong>Results: </strong>The highest mean (standard deviation) of debris extrusion weight was observed with hand files at 0.21 (0.03), followed by the Denco Gold rotary file at 0.10 (0.31), and the lowest with the Denco Blue rotary file at 0.08 (0.27). There was a significant difference (<i>P</i> < 0.001) between the rotary files and hand files, but no significant difference among the rotary files (<i>P</i> > 0.159).</p><p><strong>Conclusion: </strong>Both Denco Blue and Denco Gold rotary files resulted in less apical debris extrusion compared to hand files, with the two rotary file systems showing similar levels of debris extrusion.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"22"},"PeriodicalIF":0.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12155394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of L-arginine on hydroxyapatite-based ovine bone graft - An <i>in vitro</i> evaluation of surface characteristics and cell viability.","authors":"Maaz Vohra, Subhabrata Maiti, Khushali K Shah, Lokitha Raju, Deepak Nallaswamy, Rajalakshmanan Eswaramoorthy","doi":"10.4103/drj.drj_263_24","DOIUrl":"10.4103/drj.drj_263_24","url":null,"abstract":"<p><strong>Background: </strong>Current challenges in bone grafting revolve around the limited availability of autografts and the complications associated with their use. Promising alternatives include osteoinductive substances stimulating stem cells to mature into bone-forming osteoblasts. However, existing products lack optimal characteristics of a bone graft. The study aimed to evaluate the impact of L-arginine treatment on hydroxyapatite (HA) derived from ovine bone and compare its surface and mechanical properties to that of the commercially available xenograft-Bio-Oss.</p><p><strong>Materials and methods: </strong>The research was structured as an <i>in vitro</i> investigation, wherein HA was formulated from ovine bone. The sintering process involved heating it to 360°C for 3 h and adding the amino acid L-arginine. Different tests were done which included scanning electron microscopy (SEM), X-ray diffractometry, Fourier-transform infrared spectroscopy (FTIR), and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. The goal was to compare these results with a commercially available bone graft called BioOss, especially regarding their physical and chemical characteristics. Data were analyzed in SPSS software using one way ANOVA test, significant level at 0.05.</p><p><strong>Results: </strong>A bone graft made of HA and L-arginine displayed a complex and interconnected pore structure, indicating that the sintering process had a significant impact. SEM confirmed this. FTIR analysis identified peaks at 650-700 cm^-1 and 1000-1100 cm^-1, confirming the presence of HA and L-arginine. X-ray Diffraction assessments also confirmed the existence of both substances in the sintered specimens, supporting their suitability for various biomedical applications.</p><p><strong>Conclusion: </strong>The study presents a novel approach, deproteinizing a bone graft followed by sintering at 360°C with L-arginine. Physicochemical analyses confirmed desired mechanical attributes and surface characteristics. Further investigations are needed to evaluate cellular adherence, immunological response, and osteogenesis in relevant animal models.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"22 ","pages":"19"},"PeriodicalIF":0.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12155389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}