Dental Research Journal最新文献

筛选
英文 中文
Comparison of marginal leakage and retentive strength of implant-supported milled zirconia and cobalt-chromium copings cemented with different temporary cements. 用不同的临时水门汀粘结种植体支撑的磨制氧化锆和钴铬复合体的边缘渗漏和固位强度比较。
Dental Research Journal Pub Date : 2023-11-27 eCollection Date: 2023-01-01
Amirreza Hendi, Mehran Falahchai, Saeid Hasanpour Sigaroodi, Hamid Neshandar Asli
{"title":"Comparison of marginal leakage and retentive strength of implant-supported milled zirconia and cobalt-chromium copings cemented with different temporary cements.","authors":"Amirreza Hendi, Mehran Falahchai, Saeid Hasanpour Sigaroodi, Hamid Neshandar Asli","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Few studies assessed the effect of coping material (particularly milled metal copings) on the retentive strength of cements and reported contradictory results. Thus, this study aims to assess the marginal leakage and retentive strength of implant-supported milled zirconia and cobalt-chromium (Co-Cr) copings cemented with different temporary cements.</p><p><strong>Materials and methods: </strong>In this <i>in vitro</i> study, Zirconia and Co-Cr copings were fabricated on 100 straight titanium abutments. Each group of copings was divided into five subgroups (<i>n</i> = 10) for the use of different cements: permanent zinc-phosphate (ZP) cement, temporary zinc oxide eugenol cement (temp bond [TB]), calcium hydroxide-based temporary cement (Dycal [DC]), polymer-based eugenol-free acrylic-urethane temporary cement (Dentotemp [DT]), and methacrylate-based temporary cement (Implantlink [IL]). The retentive strength and marginal leakage of restorations were assessed. Data were analyzed by one-way ANOVA, Tukey, and Fisher's exact tests (α = 0.05).</p><p><strong>Results: </strong>In the Co-Cr group, the retentive strength values (in Newtons) were as follows: ZP (411.40 ± 5.19) >DC (248.80 ± 5.01) >IL (200.10 ± 5.06) >DT (157.90 ± 5.19) >TB (98.50 ± 6.88). This order was as follows in the zirconia group: ZP (388.70 ± 5.35) >DC (226.60 ± 5.08) >IL (179.00 ± 3.71) >DT (136.00 ± 4.88) >TB (78.60 ± 3.50). All pairwise comparisons were statistically significant (<i>P</i> < 0.001). The difference in marginal leakage was not significant among the groups (<i>P</i> = 0.480).</p><p><strong>Conclusion: </strong>The type of coping material and cement type significantly affected retentive strength, but not marginal leakage, of implant restorations. Milled Co-Cr copings showed higher retentive strength than zirconia copings, and ZP cement followed by DC yielded the highest retention.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"20 ","pages":"117"},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10758385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139086283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of hydroalcoholic extract of whole pomegranate fruit on cariogenic bacteria and its clinical effect on dental plaque formation in 8-10-year-old children. 全石榴果实水醇提取物对致癌细菌的影响及其对 8-10 岁儿童牙菌斑形成的临床效果。
Dental Research Journal Pub Date : 2023-11-27 eCollection Date: 2023-01-01
Mandana Alamdari Mahd, Parisa Aref, Fatemeh Emadi, Farnaz Javadi, Mohammad Javad Kharazi Fard, Sara Tavassoli-Hojjati
{"title":"Effect of hydroalcoholic extract of whole pomegranate fruit on cariogenic bacteria and its clinical effect on dental plaque formation in 8-10-year-old children.","authors":"Mandana Alamdari Mahd, Parisa Aref, Fatemeh Emadi, Farnaz Javadi, Mohammad Javad Kharazi Fard, Sara Tavassoli-Hojjati","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to assess the effect of hydroalcoholic extract of the whole pomegranate fruit on <i>Streptococcus mutans</i> (<i>S. mutans</i>) and <i>Lactobacillus acidophilus</i> (<i>L. acidophilus</i>) and its clinical effect on dental plaque formation in 8-10-year-old children.</p><p><strong>Materials and methods: </strong>This study was conducted in two phases of <i>in vitro</i> and clinical trial. In the <i>in vitro</i> phase, the antibacterial effect of 50%-50% hydroalcoholic extract of whole pomegranate fruit on <i>S. mutans</i> and <i>L. acidophilus</i> was assessed by the disc diffusion test. In the double-blind cross-over clinical trial phase, 14 children between 8 and 10 years were randomly assigned to two groups of 38% pomegranate mouthwash and 0.12% chlorhexidine (CHX) after assessing their baseline dental plaque by oral hygiene index-simplified (OHI-S). The children were asked not to use any other plaque control measure during the study. Their OHI-S score was measured again after 5 and 14 days using disclosing tablets. Data were analyzed by <i>t</i>-test and paired <i>t</i>-test at 0.05 level of significance.</p><p><strong>Results: </strong>The hydroalcoholic extract of pomegranate showed a positive antibacterial effect on <i>S. mutans</i> and <i>L. acidophilus</i>. However, its inhibitory effect was significantly lower than that of 0.12% CHX (<i>P</i> < 0.05). None of the tested mouthwashes inhibited plaque formation, but pomegranate mouthwash and CHX decreased the OHI-S score by 34% and 36%, respectively (<i>P</i> < 0.05), with no significant difference between them (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>The whole pomegranate fruit hydroalcoholic extract showed significant inhibitory effects on <i>S. mutans</i> and <i>L. acidophilus</i>. Furthermore, 38% pomegranate mouthwash had a comparable efficacy to CHX in the reduction of dental plaque.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"20 ","pages":"114"},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10758384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139086286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of local administration of injectable platelet-rich fibrin on root resorption during orthodontic tooth movement in dogs. 局部注射富血小板纤维蛋白对犬牙齿矫正过程中牙根吸收的影响。
Dental Research Journal Pub Date : 2023-11-27 eCollection Date: 2023-01-01
Golnoosh Sedaghati, Masood Feizbakhsh, Nasim Esnaashari, Seyed Mohammad Razavi
{"title":"Effect of local administration of injectable platelet-rich fibrin on root resorption during orthodontic tooth movement in dogs.","authors":"Golnoosh Sedaghati, Masood Feizbakhsh, Nasim Esnaashari, Seyed Mohammad Razavi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to assess the effect of local administration of injectable platelet-rich fibrin (i-PRF) on root resorption during orthodontic tooth movement in dogs.</p><p><strong>Materials and methods: </strong>This animal study was conducted on 4 adult male mongrel dogs. The right and left maxillary first premolars of the dogs were extracted, and a Nickel-Titanium closed coil spring was used to connect the canine to the second premolar with 150 g load. Next, 0.5 cc of i-PRF was injected in one quadrant of the maxilla around the second premolar into the periodontal ligament. The other quadrant of the maxilla served as the control group and received saline injection. Injections were performed at 1, 21, and 42 days, and the dogs were sacrificed after 63 days. Histological sections were prepared and cementum resorption, secondary cementum formation, and number of cementoblasts and cementoclasts were compared between the two groups by the Friedman test, Wilcoxon test, and Mann-Whitney test (α = 0.05).</p><p><strong>Results: </strong>The mean percentage of cementum resorption (17.75% ± 5.56%) and secondary cementum formation (14.50% ± 6.65%), and the mean number of cementoblasts (10.25 ± 2.36) and cementoclasts (9.75 ± 4.71) were insignificantly higher in the i-PRF group than the corresponding values (13.75% ± 4.34%, 8.50% ± 2.88%, 7.75 ± 1.25, and 6.50 ± 3.10, respectively) in the control group (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>Administration of i-PRF insignificantly increased the percentage of cementum resorption, secondary cementum formation, number of cementoblasts, and number of cementoclasts.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"20 ","pages":"118"},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10758388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139086287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep learning for tooth identification and enumeration in panoramic radiographs. 深度学习用于全景 X 光片中的牙齿识别和计数。
Dental Research Journal Pub Date : 2023-11-27 eCollection Date: 2023-01-01
Soroush Sadr, Hossein Mohammad-Rahimi, Mohammad Soroush Ghorbanimehr, Rata Rokhshad, Zahra Abbasi, Parisa Soltani, Amirhossein Moaddabi, Shahriar Shahab, Mohammad Hossein Rohban
{"title":"Deep learning for tooth identification and enumeration in panoramic radiographs.","authors":"Soroush Sadr, Hossein Mohammad-Rahimi, Mohammad Soroush Ghorbanimehr, Rata Rokhshad, Zahra Abbasi, Parisa Soltani, Amirhossein Moaddabi, Shahriar Shahab, Mohammad Hossein Rohban","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Dentists begin the diagnosis by identifying and enumerating teeth. Panoramic radiographs are widely used for tooth identification due to their large field of view and low exposure dose. The automatic numbering of teeth in panoramic radiographs can assist clinicians in avoiding errors. Deep learning has emerged as a promising tool for automating tasks. Our goal is to evaluate the accuracy of a two-step deep learning method for tooth identification and enumeration in panoramic radiographs.</p><p><strong>Materials and methods: </strong>In this retrospective observational study, 1007 panoramic radiographs were labeled by three experienced dentists. It involved drawing bounding boxes in two distinct ways: one for teeth and one for quadrants. All images were preprocessed using the contrast-limited adaptive histogram equalization method. First, panoramic images were allocated to a quadrant detection model, and the outputs of this model were provided to the tooth numbering models. A faster region-based convolutional neural network model was used in each step.</p><p><strong>Results: </strong>Average precision (AP) was calculated in different intersection-over-union thresholds. The AP50 of quadrant detection and tooth enumeration was 100% and 95%, respectively.</p><p><strong>Conclusion: </strong>We have obtained promising results with a high level of AP using our two-step deep learning framework for automatic tooth enumeration on panoramic radiographs. Further research should be conducted on diverse datasets and real-life situations.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"20 ","pages":"116"},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10758389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139086285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of probiotic yogurt, casein phosphopeptide-amorphous calcium phosphate, and xylitol chewing gums on the salivary count of Streptococcus mutans: A single-blinded randomized controlled clinical trial. 益生菌酸奶、酪蛋白磷酸肽-无定形磷酸钙和木糖醇口香糖对唾液中变异链球菌数量的影响:单盲随机对照临床试验。
Dental Research Journal Pub Date : 2023-11-27 eCollection Date: 2023-01-01
Samira Dehghani Tafti, Iman Parisay, Maryam Mehrabkhani, Sedigheh Sabbagh, Sadaf Seddigh, Kiarash Ghazvini, Naeemeh Daghestani
{"title":"Effects of probiotic yogurt, casein phosphopeptide-amorphous calcium phosphate, and xylitol chewing gums on the salivary count of <i>Streptococcus mutans</i>: A single-blinded randomized controlled clinical trial.","authors":"Samira Dehghani Tafti, Iman Parisay, Maryam Mehrabkhani, Sedigheh Sabbagh, Sadaf Seddigh, Kiarash Ghazvini, Naeemeh Daghestani","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Dental caries is a preventable multifactorial disease, with <i>Streptococcus mutans</i> being suggested to be its primary pathogen. Our study aim was to compare the effects of three different low-cost and easy-to-use regimens with that of the gold standard (chlorhexidine [CHX] mouthwash) on the count of salivary <i>S. mutans</i> in dental students over 30 days.</p><p><strong>Materials and methods: </strong>In this single-blinded parallel randomized controlled clinical trial, a total of 120 dental students were included and randomly allocated into four intervention groups: (1) CHX mouthwash (control(, (2) probiotic yogurt, (3) casein phosphopeptide-amorphous calcium phosphate chewing gum, and (4) xylitol chewing gum. Salivary <i>S. mutans</i> counts were evaluated at baseline, 15 days, and 30 days after initiation of the study and compared at different times and among different groups using the repeated measures analysis of variance design analysis and least significant difference test with SPSS software version 20. The level of significance was determined to be 0.05.</p><p><strong>Results: </strong>The microorganism count variable at baseline, first, and second follow-ups was significantly different for all groups except the probiotic yogurt group (<i>P</i> = 0.340). <i>S. mutans</i> count was significantly different when comparing the first follow-up and baseline values in the CHX and xylitol gum groups (<i>P</i> = 0.027, <i>P</i> = 0.037). When comparing the second follow-up with baseline values, a significant difference was observed in the xylitol gum group (<i>P</i> = 0.003).</p><p><strong>Conclusion: </strong>Xylitol chewing gum seems to be a viable alternative to the gold standard (CHX mouthwash) in reducing the salivary count of <i>S. mutans</i>.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"20 ","pages":"115"},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10758387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139086289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cyclin D1 and Ki-67 expression and its correlation with histopathological parameters and cervical lymph node metastasis in oral squamous cell carcinoma. 口腔鳞状细胞癌中细胞周期蛋白D1、Ki-67的表达及其与组织病理参数及颈部淋巴结转移的关系
Dental Research Journal Pub Date : 2023-10-26 eCollection Date: 2023-01-01
Saeedeh Khalesi, Laleh Maleki, Shahnaz Eskandari, Foad Zare Dehabadi, Amirhossein Yousefi Kohpaee
{"title":"Cyclin D1 and Ki-67 expression and its correlation with histopathological parameters and cervical lymph node metastasis in oral squamous cell carcinoma.","authors":"Saeedeh Khalesi, Laleh Maleki, Shahnaz Eskandari, Foad Zare Dehabadi, Amirhossein Yousefi Kohpaee","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Oral squamous cell carcinoma (OSCC) is the most common malignant tumor among oral cancers. Cyclin D1 and Ki-67 have associated with cell division. The aim of this study was to compare the expression of these markers in OSCC with and without cervical lymph node (LN) metastasis.</p><p><strong>Materials and methods: </strong>This cross-sectional study was performed on 40 OSCCs with and without cervical LN metastasis (20 in each group) that was recorded in the pathology archive of Ayatollah Kashani Hospital in Isfahan. Clinical information including age, gender, and location was collected. Some histopathological parameters including depth of invasion, lymphovascular invasion (LVI), perineural invasion (PNI), number of LN metastases, histopathological grade, and stage of disease were evaluated. Immunohistochemical staining was performed for cyclin D1 and Ki-67. All data were entered into SPSS24 software and were analyzed by Mann-Whitney, Kruskal-Wallis, Chi-square, Fisher's exact, and <i>t</i>-tests. <i>P</i> < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>Based on LVI and stage of disease, a significant correlation was found between the two groups (<i>P</i> < 0.001). There was a significant difference between the two groups based on cyclin D1 expression (<i>P</i> = 0.05). The expression of the Ki-67 showed a significant difference based on tumor location (<i>P</i> = 0.026) and PNI (<i>P</i> = 0.033).</p><p><strong>Conclusion: </strong>The use of markers should be considered in determining the prognosis of OSCC, and the cyclin D1 marker is one of the useful markers for predictors of cervical LN metastasis.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"20 ","pages":"112"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138465374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is caries prevalence site-specific in cleft lip and palate patients? A systematic review and meta-analysis. 唇腭裂患者的龋齿患病率是否有部位特异性?系统回顾和荟萃分析。
Dental Research Journal Pub Date : 2023-10-26 eCollection Date: 2023-01-01
Alpa Gupta, Simar Sethi, Jitesh Wadhwa, Puneet Batra, Elizabeth A Shick
{"title":"Is caries prevalence site-specific in cleft lip and palate patients? A systematic review and meta-analysis.","authors":"Alpa Gupta, Simar Sethi, Jitesh Wadhwa, Puneet Batra, Elizabeth A Shick","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Previous systematic reviews indicate that there is an increased prevalence of caries in cleft patients in comparison to their healthy control group. To date, the prevalence of caries between unilateral cleft lip and palate (UCLP) and bilateral cleft lip and palate (BCLP) has not been quantitatively evaluated. This review aims to include published studies that examined caries prevalence in patients with UCLP and BCLP to find out whether a quantitative difference exists in caries experience among them.</p><p><strong>Materials and methods: </strong>Medline/PubMed, Scopus, and EBSCOhost databases were searched from inception to November 2021. The protocol was registered with PROSPERO registration no. CRD2021292425. Prevalence-based studies that evaluated caries experience using the decayed-missing-filled teeth (DMFT) index in the permanent dentition or dmft in case of primary dentition in patients with UCLP or BCLP were included in the analysis with the outcome given in mean and standard deviation. Meta-analysis was performed using a random effect model through a forest plot. An adapted version of the Newcastle-Ottawa Scale for cross-sectional studies was modified to assess the quality of included studies.</p><p><strong>Results: </strong>Three studies were included in the review. The difference in caries prevalence was statistically significant in the permanent and primary dentition which were evaluated using DMFT and dmft scores with <i>P</i> = 0.01 and <i>P</i> = 0.03, respectively. Forest plot values were obtained for permanent dentition (DMFT) and primary dentition (dmft), 0.57 (95% confidence interval [CI]: 1.03-0.11) and 0.36 (95% CI: 0.69-0.03), respectively. The result of the meta-analysis indicates that patients with BCLP have higher caries prevalence.</p><p><strong>Conclusion: </strong>The outcome of the study indicates a higher occurrence of caries in patients with BCLP than UCLP in both permanent and primary dentition.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"20 ","pages":"111"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138458484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of topical curcuma longa in the healing of extraction sockets: A split-mouth clinical trial. 局部姜黄对拔牙槽愈合的疗效:一项裂口临床试验。
Dental Research Journal Pub Date : 2023-10-26 eCollection Date: 2023-01-01
Kalpa Pandya, Devee Abbinayah, Deepshika Selvakumar, Naveen Jayakumar
{"title":"Efficacy of topical <i>curcuma longa</i> in the healing of extraction sockets: A split-mouth clinical trial.","authors":"Kalpa Pandya, Devee Abbinayah, Deepshika Selvakumar, Naveen Jayakumar","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The healing process after dental extraction is influenced by various factors, and finding effective strategies for promoting wound healing and reducing postoperative discomfort remains a challenge. This study aimed to evaluate the effectiveness of topical <i>Curcuma longa</i> gel in reducing pain and promoting wound healing after dental extraction, with the secondary objective of assessing the occurrence of dry sockets. The study was a split-mouth randomized controlled trial conducted at the oral and maxillofacial surgery department over 3 months.</p><p><strong>Materials and methods: </strong>This split-mouth randomized controlled trial consisted of a total of 21 patients undergoing bilateral extractions. One extraction socket was randomly assigned to the test group, where <i>Curcuma</i>. <i>longa</i> gel was applied, while the contralateral socket served as the control group, receiving a placebo. Pain and wound healing were evaluated using standardized scales on the 3<sup>rd</sup> and 7<sup>th</sup> days postextraction. Descriptive statistics, paired <i>t</i>-tests, and unpaired <i>t</i>-tests were performed using the SPSS software version 19. The statistical significance was fixed at <i>P</i> ≤ 0.05.</p><p><strong>Results: </strong>The test group showed significantly higher mean healing scores on the 3<sup>rd</sup> and 7<sup>th</sup> days compared to the control group. On the 7<sup>th</sup> day, the test group had significantly lower mean pain scores than the control group. No cases of dry sockets were observed in either group.</p><p><strong>Conclusion: </strong>Topical Curcuma longa gel demonstrated positive effects in promoting wound healing and reducing pain after dental extraction. Clinicians should consider the use of Curcuma longa gel as a post-extraction medicament, particularly in cases involving multiple or traumatic extractions.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"20 ","pages":"110"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138458482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolation and characterization of human periodontal ligament stem cells under the terms of use in clinical application: A pilot study. 人牙周韧带干细胞在临床应用条件下的分离和表征:一项初步研究。
Dental Research Journal Pub Date : 2023-10-26 eCollection Date: 2023-01-01
Parichehr Behfarnia, Sheida Fazlalizadeh, Mohammad Hossein Nasr-Esfahani, Fatemeh Ejeian, Ahmad Mogharehabed
{"title":"Isolation and characterization of human periodontal ligament stem cells under the terms of use in clinical application: A pilot study.","authors":"Parichehr Behfarnia, Sheida Fazlalizadeh, Mohammad Hossein Nasr-Esfahani, Fatemeh Ejeian, Ahmad Mogharehabed","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The aim of the present study is to determine the possibility of isolation and characterization of the human periodontal ligament stem cells (hPDLSCs) using limited harvested periodontal ligament (PDL) tissue of only one patient's wisdom teeth (2-4 teeth) under the more compatible terms of use in clinical application without using the fetal bovine serum (FBS).</p><p><strong>Materials and methods: </strong>In this pilot study, hPDLSCs were isolated from the impacted third molar, and tissue was scraped from the roots of the impacted third molar of 10 volunteers to enzymatically digest using collagenase. The cells were sub-cultured. The samples of the first seven patients and half of the eighth patient's sample were cultured in alpha modified of Eagle's medium (α-MEM) (-FBS) medium and the other part of the eighth patient's sample was cultured with prior medium supplemented with +FBS 15% as a control of the cultivation protocol. While for the past two patients (9<sup>th</sup> and 10<sup>th</sup> the α-MEM medium was supplemented with L-Glutamine, anti/anti 2X, and 20% knock-out serum replacement (KSR). Two more nutritious supplements (N2 and B27) were added to the medium of the tenth sample. Flow-cytometric analysis for the mesenchymal stem cell surface markers CD105, CD45, CD90, and CD73 was performed. Subsequent polymerase chain reaction was undertaken on three samples cultured with two growth media.</p><p><strong>Results: </strong>Cultivation failed in some of the samples because of the lack of cell adhesion to the culturing dish bottom (floating cells), but it was successful for the 9<sup>th</sup> and 10<sup>th</sup> patients, which were cultured in the α-MEM serum supplemented with KSR 20%. Flow cytometry analysis was positive for CD105, CD90, and CD73 and negative for CD45. The PDL stem cells (PDLSCs) expressed CD105, CD45, and CD90 but were poor for CD73.</p><p><strong>Conclusion: </strong>According to the limited number of sample tests in this study, isolation and characterization of PDLSCs from collected PDL tissue of one patient's wisdom teeth (2-4) may be possible by the proper setup in synthetic FBS-free serum.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"20 ","pages":"105"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138458485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of 940-nm diode laser effectiveness on pocket depth, clinical attachment level, and bleeding on probing in chronic periodontitis: A randomized clinical single-masked split-mouth study. 评价940nm二极管激光对慢性牙周炎患者牙袋深度、临床附着水平和探诊出血的有效性:一项随机临床单掩口研究。
Dental Research Journal Pub Date : 2023-10-26 eCollection Date: 2023-01-01
Ali Seyed-Monir, Ebrahim Seyed-Monir, Sanaz Mihandoust
{"title":"Evaluation of 940-nm diode laser effectiveness on pocket depth, clinical attachment level, and bleeding on probing in chronic periodontitis: A randomized clinical single-masked split-mouth study.","authors":"Ali Seyed-Monir, Ebrahim Seyed-Monir, Sanaz Mihandoust","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Diode lasers can be used in the treatment of periodontal diseases as they have an anti-bactericidal effect, and regulate oral tissue inflammatory responses. This study aimed to evaluate the adjunctive effects of Diode 940 nm laser on mechanical periodontal debridement.</p><p><strong>Materials and methods: </strong>In this split-mouth single-blind randomized clinical trial, 12 patients were selected. Forty-four oral segments were enrolled in the scaling and root planing (SRP) group and SRP + Laser group with a 1:1 allocation ratio following a simple randomization procedure (coin flip). Clinical parameters (pocket depth, clinical attachment loss [CAL], and bleeding on probing [BOP]) were measured at baseline. After the SRP, a 940 nm Diode laser (1 Watt power and continuous wave mode) was used in the SRP + Laser group as an adjunctive treatment. The clinical parameters were remeasured 2 months posttreatment. Statistical analysis was carried out using an unpaired <i>t</i>-test with a 5% significant level by SPSS.</p><p><strong>Results: </strong>Although all clinical parameters had more improvements in the SRP + Laser group, the differences were not significant between the two study groups (<i>P</i> > 0.05). Only in individual tooth evaluations, CAL changes in first and second premolars and BOP changes in second premolars show statistically significant improvement in the SRP + L group compared to the SRP group (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Using diode 940 nm laser as an adjunctive treatment for SRP may be helpful and be suggested for periodontal treatment.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"20 ","pages":"113"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138458483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信