Antimicrobial efficacy of antiplaque agents of common toothpastes against Porphyromonas gingivalis and Streptococcus oralis: An in vitro study

Q2 Dentistry

Dental Research Journal Pub Date : 2024-03-01 DOI:10.4103/drj.drj_497_23

Narges Naghsh, J. Yaghini, T. Narimani, Elahe Khodarahmi

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Abstract

This study was designed to evaluate the antimicrobial activity of common gum protection and antiplaque toothpastes against Porphyromonas gingivalis ( P. gingivalis ) and Streptococcus oralis ( S. oralis ) as important periodontal pathogens. This experimental study investigated the antimicrobial activity of 15 commonly used toothpastes from different companies on the two common types of periopathogens, S. oralis and P. gingivalis . The antimicrobial activity of toothpaste was evaluated at three concentrations of 100%, 50%, and 25% and analyzed by agar well diffusion plate method and zone of inhibition. The obtained data were compared and statistically analyzed by SPSS software using one-way ANOVA and the least significant difference post hoc tests (α = 0.05). One-way ANOVA showed that the mean diameter of the two-bacterial zone of inhibition was significantly different at 100%, 50%, and 25% concentrations of toothpastes ( P < 0.001). In general, the mean diameter of the zone of inhibition was greater at 100% concentration than the other two concentrations in all toothpastes. The highest zone of inhibition of the S. oralis was in the toothpastes containing tin. Further, the highest zone of inhibition of P. gingivalis was found in the triclosan-containing toothpastes. Toothpastes containing triclosan had the most antimicrobial activity against P. gingivalis . Moreover, toothpastes containing tin compounds had the most antimicrobial effect against S. oralis .

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普通牙膏中的抗菌剂对牙龈卟啉单胞菌和口腔链球菌的抗菌功效：体外研究

本研究旨在评估常用牙龈保护和抗牙龈肿痛牙膏对牙龈卟啉单胞菌（P. gingivalis）和口腔链球菌（S. oralis）这两种重要牙周病原体的抗菌活性。本实验研究调查了不同公司生产的 15 种常用牙膏对两种常见牙周病原体--口腔链球菌和牙龈卟啉单胞菌的抗菌活性。牙膏的抗菌活性按 100% 、50% 和 25% 三种浓度进行评估，并采用琼脂井扩散板法和抑菌区法进行分析。所得数据通过 SPSS 软件进行比较和统计分析，采用单因素方差分析和最小显著性差异后检验（α = 0.05）。单因素方差分析表明，牙膏浓度为 100%、50% 和 25%时，双细菌抑菌区的平均直径有显著差异（P < 0.001）。一般来说，在所有牙膏中，100% 浓度的抑制区平均直径都大于其他两个浓度。含锡牙膏对口腔细菌的抑制区最大。此外，含三氯生的牙膏对牙龈脓疱病菌的抑制面积最大。含三氯生的牙膏对牙龈脓疱病的抗菌活性最强。此外，含锡化合物的牙膏对口腔细菌的抗菌效果最好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dental Research Journal Dentistry-Dentistry (all)

CiteScore

1.70

自引率

0.00%

发文量

审稿时长

52 weeks

期刊介绍： Dental Research Journal, a publication of Isfahan University of Medical Sciences, is a peer-reviewed online journal with Bimonthly print on demand compilation of issues published. The journal’s full text is available online at http://www.drjjournal.net. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository. The journal will cover technical and clinical studies related to health, ethical and social issues in field of Dentistry. Articles with clinical interest and implications will be given preference.