Dental Research Journal最新文献

{"title":"The influence of internally architected voids in the creation of high-strength, low-weight 3D-printed cobalt-chromium prototypes.","authors":"Abdullah Jasim Mohammed, Ahmed Asim Al-Ali","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The additive manufacturing technology made the topology optimization technique feasible. This technique can indefinitely reduce the weight of the printed items with a promising increase in the mechanical properties of that item.</p><p><strong>Materials and methods: </strong>In the current experimental study, 50 samples were fabricated for a 3-point bending test. They were divided into (<i>n</i> = 5) as a control Group 1 free of internal geometries, (<i>n</i> = 15) for each of Groups 2-4, and they were subdivided into (<i>n</i> = 5) for each percentage of reduction per volume (10%, 15%, and 20%). Spherical, ovoid, and diamond shapes were each group's fundamental geometries, respectively. Cylindrical tunnels connected the voids in each group. Radiographic images were performed to validate the created geometries, the weight was measured, and flexural strength and modulus of elasticity were calculated. Data were analyzed by one-way ANOVA and Duncan's <i>post hoc</i> tests at <i>P</i> < 0.05.</p><p><strong>Results: </strong>The weight results showed a significant reduction in mass. The flexural strength of Group 2 at a 10% reduction per volume had the highest mean significantly without compromising the elastic modulus. In comparison, the means of group 4 at 20% reduction showed the lowest level of toughness.</p><p><strong>Conclusion: </strong>The weight was reduced according to the reduction percentage. The flexural strength of Group 2 at a 10% reduction showed the highest degree of toughness among all groups. The void shape and density influenced the mechanical properties tested.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"21"},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11132213/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardization of honey as a tissue fixative for histopathology: A morphometric study.","authors":"B Sabarinath, Shruthi Suresh, G B Protyusha, S Dhanarathna","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Tissue fixation is a crucial step to preserve the tissues in a life-like state with minimal disruption to its cellular and chemical composition for histopathological examination. The search for an effective alternate tissue fixative to the routinely used formaldehyde has gained interest as constant exposure to formaldehyde has proven to be toxic. Honey, an organic substance with high acidity and hygroscopic nature, exhibits tissue fixative properties and has been used in the present study. The present study aimed to standardize honey as a tissue fixative for histopathology by comparing it with formalin.</p><p><strong>Materials and methods: </strong><i>In vitro</i> study Oral tissue samples of goat were fixed in 10% honey and 10% formalin solution, respectively, for 24-48 h, followed by routine tissue processing and microscopic examination of 37 slides per group. 2200 epithelial cells (1100 per group) were selected for the computer-aided morphometric image analysis (Fiji-Image J) by three observers. Cell area (CA), cell perimeter (CP), nuclear area (NA), nuclear perimeter (NP), cytoplasmic area (Cyt A), and nuclear-cytoplasmic ratio were the parameters studied. Mann-Whitney <i>U</i>-test (STATA/IC version 16) for inter-group comparison was done and <i>P</i> < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>The probability of epithelial cells in the honey-fixed group to have greater NA, NP, and N/C ratio was about 50%-60%. The probability of epithelial cells in formalin-fixed tissues to have greater CA, CP, and Cyt A was about 70%.</p><p><strong>Conclusion: </strong>Honey is a better nuclear fixative than formalin. Cytoplasmic shrinkage of epithelial cells should be taken into consideration while fixing tissues with honey.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"24"},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11132230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative finite element analysis of titanium, poly-ether-etherketone, and zirconia abutment on stress distribution around maxillary anterior implants","authors":"Angel Elias, R. F. Banu, A. Vaidyanathan, T. V. Padmanabhan","doi":"10.4103/drj.drj_769_23","DOIUrl":"https://doi.org/10.4103/drj.drj_769_23","url":null,"abstract":"\u0000 \u0000 The aim of this study was to investigate the influence of abutment material, alveolar bone density, and occlusal forces on stress distribution around maxillary anterior implants.\u0000 \u0000 \u0000 \u0000 An in-vitro study was conducted. The maxillary anterior implant was modeled using a three-dimensional finite element model in D2 and D3 bones with three different abutment materials: titanium, zirconia, and poly-ether-ether ketone (PEEK). Von Mises stress was evaluated after the application of vertical and oblique loads of 100 N, 175 N, and 250 N. Statistical analysis was done by Friedman-Wilcoxon signed-rank test, Mann-Whitney U test, and Kruskal-Wallis test. The probability value <0.05 is considered a significant level.\u0000 \u0000 \u0000 \u0000 Stress distribution around D3 bone was higher than D2 bone in all the abutment materials with greater values seen in oblique load than vertical load with insignificant difference ( P > 0.05). Statistically insignificant stress values were seen greater in PEEK than titanium or zirconia abutment ( P > 0.05). A statistically significant difference was observed between 100 N and 175 N of load ( P < 0.05).\u0000 \u0000 \u0000 \u0000 PEEK, zirconia, and titanium as abutment material in the anterior region showed similar properties. The stress on the bone was proportionately increased during the vertical and oblique loads suggesting the influence of mechanical load in crestal bone loss rather than the type of abutment material.\u0000","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"9 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140407763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial efficacy of antiplaque agents of common toothpastes against Porphyromonas gingivalis and Streptococcus oralis: An in vitro study","authors":"Narges Naghsh, J. Yaghini, T. Narimani, Elahe Khodarahmi","doi":"10.4103/drj.drj_497_23","DOIUrl":"https://doi.org/10.4103/drj.drj_497_23","url":null,"abstract":"\u0000 \u0000 This study was designed to evaluate the antimicrobial activity of common gum protection and antiplaque toothpastes against Porphyromonas gingivalis ( P. gingivalis ) and Streptococcus oralis ( S. oralis ) as important periodontal pathogens.\u0000 \u0000 \u0000 \u0000 This experimental study investigated the antimicrobial activity of 15 commonly used toothpastes from different companies on the two common types of periopathogens, S. oralis and P. gingivalis . The antimicrobial activity of toothpaste was evaluated at three concentrations of 100%, 50%, and 25% and analyzed by agar well diffusion plate method and zone of inhibition. The obtained data were compared and statistically analyzed by SPSS software using one-way ANOVA and the least significant difference post hoc tests (α = 0.05).\u0000 \u0000 \u0000 \u0000 One-way ANOVA showed that the mean diameter of the two-bacterial zone of inhibition was significantly different at 100%, 50%, and 25% concentrations of toothpastes ( P < 0.001). In general, the mean diameter of the zone of inhibition was greater at 100% concentration than the other two concentrations in all toothpastes. The highest zone of inhibition of the S. oralis was in the toothpastes containing tin. Further, the highest zone of inhibition of P. gingivalis was found in the triclosan-containing toothpastes.\u0000 \u0000 \u0000 \u0000 Toothpastes containing triclosan had the most antimicrobial activity against P. gingivalis . Moreover, toothpastes containing tin compounds had the most antimicrobial effect against S. oralis .\u0000","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"48 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140399055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of internally architected voids in the creation of high-strength, low-weight 3D-printed cobalt-chromium prototypes","authors":"Abdullah Jasim Mohammed, Ahmed Asim Al-Ali","doi":"10.4103/drj.drj_627_23","DOIUrl":"https://doi.org/10.4103/drj.drj_627_23","url":null,"abstract":"\u0000 \u0000 The additive manufacturing technology made the topology optimization technique feasible. This technique can indefinitely reduce the weight of the printed items with a promising increase in the mechanical properties of that item.\u0000 \u0000 \u0000 \u0000 In the current experimental study, 50 samples were fabricated for a 3-point bending test. They were divided into ( n = 5) as a control Group 1 free of internal geometries, ( n = 15) for each of Groups 2-4, and they were subdivided into ( n = 5) for each percentage of reduction per volume (10%, 15%, and 20%). Spherical, ovoid, and diamond shapes were each group's fundamental geometries, respectively. Cylindrical tunnels connected the voids in each group. Radiographic images were performed to validate the created geometries, the weight was measured, and flexural strength and modulus of elasticity were calculated. Data were analyzed by one-way ANOVA and Duncan's post hoc tests at P <s 0.05.\u0000 \u0000 \u0000 \u0000 The weight results showed a significant reduction in mass. The flexural strength of Group 2 at a 10% reduction per volume had the highest mean significantly without compromising the elastic modulus. In comparison, the means of group 4 at 20% reduction showed the lowest level of toughness.\u0000 \u0000 \u0000 \u0000 The weight was reduced according to the reduction percentage. The flexural strength of Group 2 at a 10% reduction showed the highest degree of toughness among all groups. The void shape and density influenced the mechanical properties tested.\u0000","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140404396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardization of honey as a tissue fixative for histopathology: A morphometric study","authors":"B. Sabarinath, Shruthi Suresh, G. Protyusha, S. Dhanarathna","doi":"10.4103/drj.drj_88_23","DOIUrl":"https://doi.org/10.4103/drj.drj_88_23","url":null,"abstract":"\u0000 \u0000 Tissue fixation is a crucial step to preserve the tissues in a life-like state with minimal disruption to its cellular and chemical composition for histopathological examination. The search for an effective alternate tissue fixative to the routinely used formaldehyde has gained interest as constant exposure to formaldehyde has proven to be toxic. Honey, an organic substance with high acidity and hygroscopic nature, exhibits tissue fixative properties and has been used in the present study. The present study aimed to standardize honey as a tissue fixative for histopathology by comparing it with formalin.\u0000 \u0000 \u0000 \u0000 \u0000 In vitro study Oral tissue samples of goat were fixed in 10% honey and 10% formalin solution, respectively, for 24-48 h, followed by routine tissue processing and microscopic examination of 37 slides per group. 2200 epithelial cells (1100 per group) were selected for the computer-aided morphometric image analysis (Fiji-Image J) by three observers. Cell area (CA), cell perimeter (CP), nuclear area (NA), nuclear perimeter (NP), cytoplasmic area (Cyt A), and nuclear-cytoplasmic ratio were the parameters studied. Mann-Whitney U-test (STATA/IC version 16) for inter-group comparison was done and P < 0.05 was considered statistically significant.\u0000 \u0000 \u0000 \u0000 The probability of epithelial cells in the honey-fixed group to have greater NA, NP, and N/C ratio was about 50%-60%. The probability of epithelial cells in formalin-fixed tissues to have greater CA, CP, and Cyt A was about 70%.\u0000 \u0000 \u0000 \u0000 Honey is a better nuclear fixative than formalin. Cytoplasmic shrinkage of epithelial cells should be taken into consideration while fixing tissues with honey.\u0000","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"26 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140407664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between three methods of diode laser 810 nm, photodynamic therapy with laser 660 nm, and hypochlorite solution for disinfection of pulp canal of primary teeth","authors":"Nima Amini Tehrani, S. Javadinejad, A. Shirani","doi":"10.4103/drj.drj_82_23","DOIUrl":"https://doi.org/10.4103/drj.drj_82_23","url":null,"abstract":"\u0000 \u0000 The presence of treatment-resistant microorganisms is known as the main cause of pulpectomy failure in the endodontic treatment of deciduous teeth. The usage of lasers can contribute to reducing these microorganisms. This study aimed to compare the effect of three disinfection methods for deciduous teeth canals using laser diode 810 nm, photodynamic therapy with laser 660 nm and methylene blue, and sodium hypochlorite.\u0000 \u0000 \u0000 \u0000 In this experimental study, 58 single-root deciduous teeth with no root resorption were investigated in four groups, including one control group of 10 and three intervention groups of 16. Preparation of the samples was done using manual files up to three numbers after the initial file. After sterilizing the samples in an autoclave, Enterococcus faecalis bacteria were cultured in the canals. In the first group, irrigating with hypochlorite 2.5% was done; in the second group, photodynamic therapy was performed using a laser diode and 0.1 mg/mL methylene solution; and in the third group, high-intensity laser 810 nm direct radiation was done into the canal. Next, samples were taken from all canals. The colony formation unit (CFU) of the bacteria was counted in the blood agar culture medium. The data were analyzed using Kruskal-Wallis and negative binomial regression test (α =0.05).\u0000 \u0000 \u0000 \u0000 The mean CFU differed significantly between the four groups. The rate of incidence of E. faecalis colonies showed a reduction in all three intervention groups compared to the negative control. In the high-intensity laser 810 nm group, there was 68.4%; in the photodynamic therapy with diode 660 nm and methylene blue, there was 88%; and in the hypochlorite group, 98.3% reduction was observed compared to the negative control group.\u0000 \u0000 \u0000 \u0000 Based on the results of this study, to compare three disinfection methods of the deciduous teeth canals without preparation of canals, sodium hypochlorite had greater efficiency. All three groups of laser, photodynamic therapy, and sodium hypochlorite showed reductions of E. faecalis bacterial colony compared to the control group. The reductive effects of CFU were greater in the hypochlorite sodium group, followed by photodynamic and direct laser radiation groups.\u0000","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"306 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140402343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of taste score and fungiform papillae quantification using digital image analysis in COVID-19 patients with smell and taste dysfunction.","authors":"Vidya Chikkarahalli Srikantaiah, Anil Somashekara Bilimale, Vidya Gowdappa Doddawad, Srinath Kenkere Marulaiah, Hathur Basavana Gowdappa, Ranjitha Shankaregowda, Basavegowda Madhu, Amulya Manohar Thotambailu, Raghu Ram Achar","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a major global health crisis in recent years. Despite this, there have been few studies that have utilized reliable methods to assess changes in taste and smell perception. Therefore, our study aims at the number of fungiform papillae and objective measures of taste perception relationship among COVID-19 patients with olfactory and gustatory disorders.</p><p><strong>Materials and methods: </strong>This was a cross-sectional analytical study in which 57 COVID-19 patients were recruited who confirmed the dysfunction of taste and smell. Objective assessment of the sense of taste was evaluated using four different standardized solution preparations, and the scores were given according to the patient's statements. Digitalized quantification of fungiform papillae was counted. The data were analyzed with the Pearson's correlation coefficient using the SPSS version. 23 [Licensed JSSAHER, Mysuru, Karnataka, India], and the level of significance was set at <0.001.</p><p><strong>Results: </strong>In terms of altered or reduced taste and smell, male patients exhibited a higher incidence compared to females. Compared to the sour taste, a substantial number of COVID-19 patients have displayed a notable decrease in their ability to taste sweet, salty, and bitter flavors. However, a statistically significant positive correlation was observed between taste scores and fungiform papillae density (<i>r</i> = 0.518, <i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Our Study demonstrated that the quantitative evaluation of taste perception and the count of fungiform papillae can serve as important indicators of SARS-CoV-2 infection, and could potentially help in the early detection and treatment of COVID-19 patients, as reduced taste function is a significant marker of the disease.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"11"},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10929720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140109544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphometric parameters of dental pulp in immature teeth in a sheep model after mechanical pulp exposure and restoration with reinforced zinc oxide-eugenol.","authors":"Eshaghali Saberi, Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb, Mahdieh Narouei, Lida Jafari, Alireza Mahmoudzadeh-Sagheb, Mahmoud Saadatian","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The aim of the study was to investigate the morphometric parameters of dental pulp in open apices immature teeth in a sheep model after mechanical pulp exposure and restoration with reinforced zinc oxide-eugenol.</p><p><strong>Materials and methods: </strong>In this experimental study, a total of 12 immature mandibular central incisors from six adult male sheep, weighing 30-40 kg and with the age of 1 year old with Merino race were examined. After anesthesia, the pulps of the teeth in the case group were mechanically exposed and then were restored with reinforced zinc oxide-eugenol and amalgam. In the control group, the teeth remained intact. The animals were sacrificed at intervals of 2, 4, 6, and 8 weeks (E2, E4, E6, and E8) in the case and 2 and 8 weeks (C2 and C8) in the control groups. Then, their teeth were removed with the surrounding supporting tissues and alveolar bones. Tissue processing and staining were done, and the sections were examined under a light microscope. The Kruskal-Wallis and Mann-Whitney <i>U</i> tests were used to analyze the data and compare the changes between the two groups. <i>P</i> < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>In response to mechanical exposure, reparative or tertiary dentin was formed, and its thickness increased during the time of the study. The thickness of the odontoblastic layer in the E4 group was the highest amount. The pulp chamber diameter in the C2 group was significantly larger than the other groups, and the diameter of the apical foramen in the E8 was decreased significantly compared to the controls (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>In response to mechanical exposure and restoration with reinforced zinc oxide-eugenol, some morphometric parameters of the dental pulp changed significantly in the sheep model compared to the controls.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"17"},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10929729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140109545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between periodontal disease and obstructive sleep apnea in adults: A systematic review.","authors":"Edoardo Bianchi, Marzia Segù, Andrea Toffoli, Geremia Razzini, Guido Maria Macaluso, Edoardo Manfredi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of this systematic review was to evaluate whether there are scientific evidence regarding the association between periodontitis and obstructive sleep apnea (OSA) in adults. An electronic search was performed on MEDLINE/PubMed for prospective and retrospective longitudinal studies, cohort studies, and case-control studies conducted in human adults affected by both OSA and periodontitis. Two reviewers extracted the data using a custom Excel spreadsheet. A methodological assessment of the quality of the studies was performed using the Newcastle-Ottawa Scale. Fourteen studies were included. All studies evaluated the association between periodontitis and OSA. None of the studies evaluated the cause-effect relationship. Eleven studies found a significant positive relationship between periodontitis and OSA, whereas three found no statistically significant association. Several study limitations were observed, such as lack of standardization of study groups, diagnosis of periodontitis and OSA, and differences in study design. Evidence of a plausible association between periodontitis and OSA was found. The possible relationship could be explained by systemic inflammation, oral breathing, and the comorbid relationship attributable to common risk factors. Observational and randomized controlled studies are needed to clarify the mechanism of interaction between the two conditions.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"15"},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10929726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140109546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}